Datasets:

everycure
/

indications-list

ec_id stringlengths 8 8	translator_id stringlengths 10 29	drugbank_id stringlengths 7 12 ⌀	drug_name stringlengths 5 40	target stringlengths 13 13	disease_name stringlengths 4 144	on_label bool 2 classes	off_label bool 2 classes	__index_level_0__ int64 10 4.21k
EC:00003	UNII:7D0YB67S97	DB01281	Abatacept	MONDO:0011429	Juvenile idiopathic arthritis	true	false	10
EC:00003	UNII:7D0YB67S97	DB01281	Abatacept	MONDO:0020546	acute graft versus host disease	true	false	11
EC:00003	UNII:7D0YB67S97	DB01281	Abatacept	MONDO:0011849	psoriatic arthritis	true	false	12
EC:00003	UNII:7D0YB67S97	DB01281	Abatacept	MONDO:0008383	rheumatoid arthritis	true	false	13
EC:00006	UNII:73SM5SF3OR	DB14973	Abrocitinib	MONDO:0004980	atopic eczema	true	false	14
EC:00007	CHEBI:167707	DB11703	Acalabrutinib	MONDO:0100280	Waldenstrom macroglobulinemia	false	true	16
EC:00008	CHEBI:51041	DB00659	Acamprosate	MONDO:0007079	Alcohol dependence	true	false	17
EC:00008	CHEBI:51041	DB00659	Acamprosate	MONDO:0002046	Alcohol abuse	true	false	18
EC:00010	CHEBI:2379	DB01193	Acebutolol	MONDO:0001134	Essential hypertension	true	false	19
EC:00010	CHEBI:2379	DB01193	Acebutolol	MONDO:0004425	hyperthyroidism	false	true	20
EC:00010	CHEBI:2379	DB01193	Acebutolol	MONDO:0010138	thyrotoxicosis	false	true	23
EC:00011	CHEBI:31159	DB06736	Aceclofenac	MONDO:0005306	ankylosing spondylitis	true	false	24
EC:00011	CHEBI:31159	DB06736	Aceclofenac	MONDO:0005178	osteoarthritis	true	false	25
EC:00011	CHEBI:31159	DB06736	Aceclofenac	MONDO:0008383	rheumatoid arthritis	true	false	27
EC:00011	CHEBI:31159	DB06736	Aceclofenac	MONDO:0006898	periarthritis	true	false	28
EC:00014	CHEBI:27690	DB00819	Acetazolamide	MONDO:0021811	Acute mountain sickness	true	false	29
EC:00014	CHEBI:27690	DB00819	Acetazolamide	MONDO:0008223	hypokalemic periodic paralysis	false	true	30
EC:00014	CHEBI:27690	DB00819	Acetazolamide	MONDO:0001817	acute closed-angle glaucoma	true	false	31
EC:00014	CHEBI:27690	DB00819	Acetazolamide	MONDO:0009468	pseudotumor cerebri	false	true	32
EC:00016	CHEBI:94688	DB09055	Acipimox	MONDO:0011470	hyperlipidemia, combined, 2	true	false	33
EC:00016	CHEBI:94688	DB09055	Acipimox	MONDO:0007788	hypertriglyceridemia 1	true	false	35
EC:00017	CHEBI:50173	DB00459	Acitretin	MONDO:0007417	Darier disease	false	true	37
EC:00017	CHEBI:50173	DB00459	Acitretin	MONDO:0100017	pityriasis rubra pilaris	true	false	38
EC:00021	CHEBI:83168	DB09488	Acrivastine	MONDO:0044212	chronic idiopathic urticaria	true	false	39
EC:00021	CHEBI:83168	DB09488	Acrivastine	MONDO:0005324	seasonal allergic rhinitis	true	false	40
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0005306	ankylosing spondylitis	true	false	41
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0007191	Behcet disease	false	true	42
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0005011	Crohn disease	true	false	43
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0005532	Crohn's colitis	true	false	44
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0000709	Crohn ileitis	true	false	45
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0006559	hidradenitis suppurativa	true	false	46
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0011429	juvenile idiopathic arthritis	true	false	47
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0011849	psoriatic arthritis	true	false	49
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0018824	pyoderma gangrenosum	false	true	53
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0008383	rheumatoid arthritis	true	false	54
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0019338	sarcoidosis	false	true	61
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0005095	spondyloarthropathy	true	false	62
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0005101	ulcerative colitis	true	false	63
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0006918	posterior uveitis	true	false	64
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0017255	panuveitis	true	false	65
EC:00024	UNII:FYS6T7F842	DB00051	Adalimumab	MONDO:0006806	intermediate uveitis	true	false	66
EC:00025	CHEBI:31174	DB00210	Adapalene	MONDO:0006604	rosacea	false	true	68
EC:00029	CHEBI:136034	DB04931	Afamelanotide	MONDO:0001676	erythropoietic protoporphyria	true	false	69
EC:00033	UNII:2HLC17MX9G	DB15874	Agalsidase beta	MONDO:0010526	Fabry disease	true	false	70
EC:00034	CHEBI:134990	DB06594	Agomelatine	MONDO:0002009	major depressive disorder	true	false	71
EC:00036	CHEBI:2549	DB01001	Albuterol	MONDO:0004979	asthma	true	false	72
EC:00036	CHEBI:2549	DB01001	Albuterol	MONDO:0850286	exercise-induced bronchoconstriction	true	false	73
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0020546	acute graft versus host disease	false	true	74
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0015909	aplastic anemia	false	true	75
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0004948	B-cell chronic lymphocytic leukemia	true	false	76
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0015544	acquired hemophagocytic lymphohistiocytosis associated with malignant disease	false	true	77
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0015542	secondary hemophagocytic lymphohistiocytosis	false	true	79
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0015541	hereditary hemophagocytic lymphohistiocytosis	false	true	80
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0000452	Progressive, relasping multiple sclerosis	true	false	81
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0005314	relapsing-remitting multiple sclerosis	true	false	82
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0005301	multiple sclerosis	true	false	83
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0009691	mycosis fungoides	false	true	84
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0019469	T-cell large granular lymphocyte leukemia	false	true	86
EC:00041	UNII:3A189DH42V	DB00087	Alemtuzumab	MONDO:0019468	T-cell prolymphocytic leukemia	false	true	87
EC:00042	CHEBI:2567	DB00630	Alendronate	MONDO:0024651	corticosteroid-induced osteoporosis	false	true	88
EC:00042	CHEBI:2567	DB00630	Alendronate	MONDO:0005298	osteoporosis	true	false	89
EC:00042	CHEBI:2567	DB00630	Alendronate	MONDO:0008159	postmenopausal osteoporosis	true	false	90
EC:00042	CHEBI:2567	DB00630	Alendronate	MONDO:0005382	bone Paget disease	true	false	91
EC:00044	CHEBI:51141	DB00346	Alfuzosin	MONDO:0010811	benign prostatic hyperplasia	true	false	92
EC:00044	CHEBI:51141	DB00346	Alfuzosin	MONDO:0024647	urolithiasis	false	true	93
EC:00046	UNII:PP0SHH6V16	DB09302	Alirocumab	MONDO:0018328	homozygous familial hypercholesterolemia	true	false	94
EC:00046	UNII:PP0SHH6V16	DB09302	Alirocumab	MONDO:0001336	familial hyperlipidemia	true	false	95
EC:00046	UNII:PP0SHH6V16	DB09302	Alirocumab	MONDO:0021187	hyperlipidemia	true	false	97
EC:00049	CHEBI:40279	DB00437	Allopurinol	MONDO:0005393	gout	true	false	98
EC:00049	CHEBI:40279	DB00437	Allopurinol	MONDO:0957318	nephrolithiasis, calcium oxalate	true	false	99
EC:00049	CHEBI:40279	DB00437	Allopurinol	MONDO:0008171	nephrolithiasis	false	true	101
EC:00049	CHEBI:40279	DB00437	Allopurinol	MONDO:0043875	Tumor lysis syndrome	true	false	102
EC:00055	CHEBI:2611	DB00404	Alprazolam	MONDO:0001942	generalized anxiety disorder	true	false	104
EC:00055	CHEBI:2611	DB00404	Alprazolam	MONDO:0005383	panic disorder	true	false	106
EC:00055	CHEBI:2611	DB00404	Alprazolam	MONDO:0002317	central nervous system origin vertigo	false	true	107
EC:00056	CHEBI:15544	DB00770	Alprostadil	MONDO:0005362	Erectile Dysfunction	true	false	108
EC:00056	CHEBI:15544	DB00770	Alprostadil	MONDO:0011827	patent ductus arteriosus	true	false	109
EC:00056	CHEBI:15544	DB00770	Alprostadil	MONDO:0008364	Raynaud disease	false	true	110
EC:00057	UNII:1RXS4UE564	DB00009	Alteplase	MONDO:0005279	pulmonary embolism	true	false	111
EC:00057	UNII:1RXS4UE564	DB00009	Alteplase	MONDO:0041656	ST-elevation myocardial infarction	true	false	114
EC:00058	CHEBI:33130	DB06723	Aluminium hydroxide	MONDO:0002268	dyspepsia	true	false	115
EC:00058	CHEBI:33130	DB06723	Aluminium hydroxide	MONDO:0000328	hyperphosphatemia	true	false	116
EC:00059	CHEBI:135686	DB06274	Alvimopan	MONDO:0004567	Ileus	true	false	117
EC:00060	CHEBI:2618	DB00915	Amantadine	MONDO:0006966	secondary Parkinson disease	true	false	118
EC:00060	CHEBI:2618	DB00915	Amantadine	MONDO:0019790	neuroleptic malignant syndrome	false	true	119
EC:00060	CHEBI:2618	DB00915	Amantadine	MONDO:0005180	Parkinson disease	true	false	120
EC:00060	CHEBI:2618	DB00915	Amantadine	MONDO:0005391	restless legs syndrome	false	true	121
EC:00060	CHEBI:2618	DB00915	Amantadine	MONDO:0010096	tardive dyskinesia	false	true	123
EC:00060	CHEBI:2618	DB00915	Amantadine	MONDO:0858950	traumatic brain injury	false	true	124
EC:00061	CHEBI:135949	DB06403	Ambrisentan	MONDO:0015924	pulmonary arterial hypertension	true	false	126
EC:00063	CHEBI:135948	DB11640	Amifampridine	MONDO:0018556	Lambert-Eaton myasthenic syndrome	true	false	127
EC:00064	CHEBI:2636	DB01143	Amifostine	MONDO:0019084	radiation proctitis	false	true	128
EC:00066	CHEBI:2639	DB00594	Amiloride	MONDO:0005578	arthritis	false	true	129
EC:00066	CHEBI:2639	DB00594	Amiloride	MONDO:0001134	essential hypertension	true	false	130
EC:00066	CHEBI:2639	DB00594	Amiloride	MONDO:0005377	nephrotic syndrome	false	true	132
EC:00067	UNII:41KZS5432U	DBSALT002730	Aminobenzoate potassium	MONDO:0016367	dermatomyositis	true	false	133
EC:00069	CHEBI:17549	DB00855	Aminolevulinic acid	MONDO:0043300	Actinic cheilitis	false	true	134
EC:00069	CHEBI:17549	DB00855	Aminolevulinic acid	MONDO:0005173	Actinic keratosis	true	false	135
EC:00069	CHEBI:17549	DB00855	Aminolevulinic acid	MONDO:0005341	skin basal cell carcinoma	false	true	136
EC:00069	CHEBI:17549	DB00855	Aminolevulinic acid	MONDO:0020761	Bowen disease of the skin	false	true	138

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Dataset Card for Every Cure Indications list

Dataset Summary

The Every Cure Indications List is a manually curated list of on-label and off-label indications used by the MATRIX project for drug repurposing predictions.

The indications collected in the list focus on interventional treatments therefore indications used for preventative treatment or symptomatic relief are not included in the list.

For reference, the list contains ~2,700 drug-disease pairs out of which approximately 700 are off label indications. The list is compatible with datasets available in the HF dataset repository

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Homepage:

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