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Anti-arrhythmics: Hypokalaemia caused by loop diuretics increases cardiac toxicity with amiodarone, disopyramide, flecainide, and antagonises the action of lidocaine and mexiletine. |
Antibacterials: Avoid the use of diuretics in lymecycline treatment. There is an increased risk of ototoxicity when loop diuretics are given with aminoglycosides, polymyxins or vancomycin. Since this may lead to irreversible damage, these drugs must only be used with furosemide if there are compelling medical reasons. Impairment of renal function may develop in patients receiving concurrent treatment with furosemide and high doses of certain cephalosporins. |
Antidepressants: Possible increase of hypokalaemia when loop diuretics are given with reboxetine. There is an enhanced hypotensive effect when diuretics are given with MAOIs. There is an increased risk of postural hypotension when diuretics are given with tricyclic antidepressants. |
Antiepileptics: There is an increased risk of hyponatraemia when diuretics are given with carbemazepine. The effects of furosemide are antagonised by phenytoin. |
Antifungals: There is an increased risk of hypokalaemia when loop diuretics are given with amphotericin. |
Antipsychotics: Hypokalaemia caused by diuretics increase the risk of ventricular arrhythmias with amisulpiride or sertindole. An enhanced hypotensive effect may be seen when diuretics are given with phenothiazines. Hypokalaemia caused by diuretics increases risk of ventricular arrhythmias with pimozide (avoid concomitant use). |
Antivirals: Plasma concentration of diuretics may be increased by nelfinavir, ritonavir or saquinavir. |
Atomoxetine: Hypokalaemia caused by diuretics increases the risk of ventricular arrhythmias with atomoxetine. |
Barbiturates: Plasma concentrations of diuretics may be decreased. There may be an increased risk of osteomalacia when diuretics are taken in combination with Phenobarbital. |
Beta-blockers: There is an enhanced hypotensive effect when diuretics are given with beta-blockers. Hypokalaemia caused by loop diuretics increases the risk of ventricular arrhythmias with sotalol. |
Cardiac glycosides: Hypokalaemia caused by loop diuretics increases cardiac toxicity with cardiac glycosides. |
Ciclosporin: there is an increased risk of nephrotoxicity and possibly hypermagnesaemia when diuretics are given with ciclosporin. |
Cisplatin: There is a risk of increased ototoxic effects if cisplatin and furosemide are given concomitantly. In addition, nephrotoxicity of cisplatin may be enhanced if furosemide is not given in low doses (e.g. 40mg in patients with normal renal function) and with positive fluid balance when used to achieve forced diuresis during cisplatin treatment. |
Corticosteroids: The diuretic effect of diuretics is antagonized by corticosteroids. There is an increased risk of hypokalaemia when loop diuretics are given with corticosteroids. |
Other Diuretics: There is an increased risk of hypokalaemia when loop diuretics are given with acetazolamide. Profound diuresis is possible when metolazone is given with furosemide. There is an increased risk of hypokalaemia when loop diuretics are given with thiazides and related diuretics. |
Lithium: Loop diuretics reduce the excretion of lithium, which may lead to increased plasma concentrations and a risk of toxicity. Therefore, it is recommended that lithium levels are carefully monitored and where necessary the lithium dosage is adjusted in patients receiving this combination. |
Potassium salts: There is an increased risk of hyperkalaemia when given with potassium salts. |
Sucralfate: Furosemide and sucralfate must not be taken within 2 hours of each other as sucralfate decreases the absorption of furosemide from the intestine and so reduces its effect. |
Sympathomimetics, Beta2: There is an increased risk of hypokalameia when loop diuretics are given with high doses of beta2 synpathomimetics. |
Tacrolimus: There is an increased risk of hypokalaemia when given with tacrolimus. |
Theophylline: There is an increased risk of hypokalaemia when loop diuretics are given with theophylline. |
Carbenoxolone, prolonged use of laxatives, liquorice: May increase the risk of developing hypokalaemia. |
Warfarin and clofibrate: Warfarin and clofibrate compete with furosemide in the binding to serum albumin. This may have clinical significance in patients with low serum albumin levels (e.g. in nephrotic syndrome). Furosemide does not change the pharmacokinetics of warfarin to a significant extent, but a strong diuresis with associated dehydration may weaken the antithrombotic effect of warfarin. |
Probenecid, methotrexate and other drugs which, like furosemide, undergo significant renal tubular secretion may reduce the effect of furosemide. Conversely, furosemide may decrease renal elimination of these drugs. In case of high-dose treatment (in particular, of both furosemide and the other drugs), this may lead to increased serum levels and an increased risk of adverse effects due to furosemide or the concomitant medication. |
Risperidone: When administering risperidone, caution should be exercised and the risks and benefits of the combination or co-treatment with furosemide or with other potent diuretics should be considered prior to the decision to use. See section 4.4 Special warnings and precautions for use regarding increased mortality in elderly patients with dementia concomitantly receiving risperidone. |
Results of animal work, in general, show no hazardous effect of furosemide in pregnancy. There is clinical evidence of safety of the drug in the third trimester of human pregnancy; however, furosemide crosses the placental barrier. It must not be given during pregnancy unless there are compelling medical reasons. Treatment during pregnancy requires monitoring of fetal growth. |
Furosemide passes into breast milk and may inhibit lactation. Breastfeeding must be avoided during treatment with furosemide. |
No human data on the effect of furosemide on fertility are available. In rats, there was no effect on mating or fertility with furosemide treatment. |
Mental alertness may be reduced and the ability to drive or operate machinery may be impaired. |
In general, if furosemide is administered to premature infants during the first weeks of life, it may increase the risk of persistence of patent ductus arteriosus. Risk of nephrocalcinosis/ nephroliathisis. |
The clinical picture in acute or chronic overdose depends primarily on the extent and consequences of electrolyte and fluid loss, e.g. hypovolaemia, dehydration, haemoconcentration, cardiac arrhythmias – including A-V block and ventricular fibrillation. Symptoms of these disturbances include severe hypotension (progressing to shock), acute renal failure, thrombosis, delirious states, flaccid paralysis, apathy and confusion. |
There are no specific antidotes to furosemide. If the ingestion is recent, attempts to limit further systemic absorption may be performed, through gastric lavage or others measures that may minimize absorption (i.e. activated charcoal). |
The clinically relevant fluid and electrolyte balance changes must be corrected. Along with the prevention and treatment of serious complications resulting from such imbalances and other effects in the body, this corrective action may require general and specific intensive medical monitoring and therapeutic measures. |
Furosemide is a potent loop diuretic which inhibits sodium and chloride reabsorption at the Loop of Henlé. The drug eliminates both positive and negative free water production. Furosemide acts at the luminal face of the epithelial cells by inhibiting co-transport mechanisms for the entry of sodium and chloride. Furosemide gains access to its site of action by being transported through the secretory pathway for organic acids in the proximal tubule. It reduces the renal excretion of uric acid. Furosemide causes an increased loss of potassium in the urine and also increases the excretion of ammonia by the kidney. |
Furosemide is a weak carboxylic acid which exists mainly in the dissociated form in the gastro-intestinal tract. Furosemide is rapidly but incompletely absorbed (60-70%) on oral administration and its effect is largely over within four hours. The optimal absorption site is the upper duodenum at pH 5.0. Regardless of route of administration, 69-97% of activity from a radio-labelled dose is excreted in the first 4 hours after the drug is given. Furosemide is mainly eliminated via the kidneys (80-90%); a small fraction of the dose undergoes biliary elimination and 10-15% of the activity can be recovered from the faeces. |
When oral doses of Furosemide are given to normal subjects the mean bioavailability of the drug is approximately 52% but the range is wide. In plasma, Furosemide is extensively bound to proteins mainly to albumin. The unbound fraction in plasma averages 2 - 4% at therapeutic concentrations. The volume of distribution ranges between 170 - 270ml/Kg. The half life of the ß phase ranges from 45 - 60 min. The total plasma clearance is about 200ml/min. Renal excretion of unchanged drug and elimination by metabolism plus faecal excretion contribute almost equally to the total plasma clearance. Furosemide is in part cleared by the kidneys in the form of the glucuronide conjugate. |
Dosing Device: 10ml oral syringe with 0.5ml graduation mark supplied with an LDPE syringe adaptor. |
MACON, Ill. – Griz FM 98.1 Fan Appreciation Night features the State Street Stocks Championship and the Big Ten Series Street Stocks Championship, but the fun doesn’t stop here at legendary Macon Speedway Saturday. With general admission for ladies only $6 on Bud Light Ladies Night and the gals racing from Pop’s Place plus racing in six classes on the fifth-mile high banked oval, it’s a great night to head to the famed speedway on the holiday weekend. |
As of 1 p.m. Saturday, preparations were underway for racing at Macon Speedway. Check Maconracing.com for further updates throughout the day. |
The Midwest Big Ten Series Street Stocks will bring some fireworks to an already competitive class. With the $1,000 prize for the season championship up for grabs, the $500 to win feature race, a dash for cash, some trophies on the line and qualifying for the dirt stock cars, it’s the biggest Street stocks event in the state this season. Terry Reed of Decatur and Bobby Beiler of Blue Mound battle for the championship, and the points fund payout extends through the top 10. There’s plenty of places up for grabs with a driver’s top eight finishes counting toward his Big Ten Series points total. |
Bud Light Ladies Night presented by Y103 features the ladies from Pop’s Place as they hop into 4-cylinder Hornets in an effort to advance to the Bud Light Ladies Night finals in September. Michelle Perry, Karey Keller, Genny Hinton, Christine Vogel and Stephanie Keenan will attempt to join Jenny Cramer and Dana Damery of Rocco’s, Dawn Reynolds and Holly Vinson of Starship Billiards and Laurel Phipps and Brianna Livingston of Woody’s in the Bud Light Ladies Night Championship on Sept. 13. So with that many women heading to Macon Speedway, it’s a great time for the guys to make sure they get here and grab some Buds. |
Sentiments/Non-Humans: Mostly indifferent, sees most human-like D-bees as just another human, still can't help but stare at D-bees that are very different/alien. |
Sentiments/Coalition: Thinks of them as stuck up at best, no matter what his superiors and the government say. |
Disposition: Generally friendly sort of fellow, hangs out with the rest of the squad when off duty. On-duty he takes his job seriously, though he is not the by-the-book sort and will bend or out-right break the rules if the situation calls for it. |
Description: Athletic, wiry build, green eyes, black hair that is long on the top and pulled back into a warriors knot and shaved on the sides, also has a fair number of tattoos across his back, chest, & arms. These tattoos are a collage of power armor suits and robot vehicles from every manufacturer that sells these types of units in North America with steam-punk designs tying the individual pieces together. |
Max. Carrying Weight: 250 lbs. |
Max. Lifting Weight: 500 lbs. |
Triple Damage against Robots when a "natural," unmodified 18, 19 or 20 is rolled on an Aimed Shot. This applies only to robots and not power armor exoskeletons. |
armor, vehicles and robot vehicles by 5%. |
Spiritual and Determined: +2d4 to M.E. |
Spiritual and Determined: Inner Strength; has additional P.P.E. and can use TW items. |
Agile and Dexterous: +2d4 to P.P. |
Agile and Dexterous: Ambidextrous trait; Can use both the right and left hand with equal skill and dexterity; Paired Weapons skill is automatic. +1 APM, +10% to Climbing skills, +5% to Pick Locks, Pick Pockets, Palming, and Concealment skills. |
Cannot be surprised, even from behind. |
W.P. - Sharpshooting: Handgun; +1 attack per melee, Aimed: +3 strike, Called: +5 strike, Quick Draw: +4 initiative, Trick Shooting: Dodge, roll, or somersault and come up shooting, these are in addition to W.P. - Handgun bonuses. |
Last edited by Victor Singer on Mon Oct 22, 2018 3:16 pm, edited 66 times in total. |
NG-X67 "Prophet" Infantry Power Armor - "Milashka" |
* -4 to strike on a called shot, and must be a Called shot. |
** Depleting the Main Body of MDC will shut the suit down. |
*** Force field regenerates at a rate of 1 MDC/melee round. |
Cat-like landings from heights: up to 200' without damage. |
Criminal I.D. Recognition System; Is programmed with 250,000 known criminals, wanted fugitives, Black Marketeers, terrorists, enemies of the state, bounties, identifying markings, known gang emblems, symbols, emblems, patches, & colors. |
Advanced Camera; this is mounted in the helmet has and has superior telescopic zoom (Range: 2 miles) and a macro-lens (x12 magnification), it can take stills & video (96 hours & 8,000 images), and it can be transmitted live (Range: 5 miles). |
Digital Dash-Cams (8); two in the helmet, 2 in the chest, 1 in each forearm, 2 in the back w 48 hours of record time & can take 4,000 stills. |
Peekaboo Cameras (2); located behind the left & right shoulders, can be used to peak around corners or through foliage without exposing oneself. |
Special & Standard Helmet Optics; Passive night-vision, Thermal imaging, IR, UV, black-light, laser distancer, IR light, & voice modulation (20 variations). |
Warning System & Multi-Cameras; Tied into the cameras & sensor array is a motion detection warning system that gives an audible voice warning/notification when the system picks up or spots something notable within 100'. This includes not only incoming fire or danger, direction, distance, but also subjects picked up by the Criminal I.D. System meaning it will give information about said subject as well, at least info it has in its files. This is basic info like name, race, friendly/hostile, or gang/group affiliation. |
Note: Used, has only 65 MDC, -5% Prowl (only to prowl, other movement is fine). A skilled operator could repair the suit to bring it to full MDC, but it would take double normal time. The Prowl penalty can be removed by redoing the fabric lining of the suit. What Victor didn't notice is that the legs have some bad repair to the fabric lining, it crinkles and cracks as the wearer moves. What he did notice is that the suit has been outfitted with four concealed pockets. One on the back is useful for a medium or smaller handgun. Two are on the inside of thighs are are suitable for hiding papers or the like (such as maps). The third is on the inside of the chest, it's only accessible when the suit is off. It can hold a larger volume of flat stuff compared to the thighs. |
• Mega-Damage: 2d4 M.D. or 4d6 M.D. |
• Mega-Damage: 3d6 M.D. or 1d4x10 M.D. |
• Weapons: None built in. |
• Note: May overheat if used continuously for more than four hours (01-40%). Overheating will destroy the machine; should be allowed to cool for two hours after every two or three hours of continuous use. |
Note: Used, has only 28 MDC, gets only 750 miles per charge, 12 years old. Otherwise in great working order. It would take rebuilding the housing almost completely to get the MDC back. Installing a new battery would restore the range to 800 miles. |
The brain child of the KLS corporation, this rail gun design is a miniaturized version of the RG-14 Electromagnetic Mass Driver. It's flexibility, efficiency, and relatively light weight make it the most potent man-portable, anti-armor & anti-demon weapon system ever produced. The only drawback is the delay in discharge as the capacitors spool up to release the hypersonic sabot payload. Several cases of these rifles have been released for field testing. |
Helical magazines must be custom made by highly skilled weapons shops and have a base cost of 1000 credits each. |
APDS rounds must be custom made by highly skilled weapons shops and have a base cost of 250 credits each. |
two sets of street clothes, pocket flashlight, tinted goggles, small digital photo album that has pictures of his family & friends, box of disposable plastic gloves (100 per box), three weeks of freeze-dried combat rations, duffle bag, air filter, 2-person tent, hunting & fishing kit, 30' of lightweight climbing rope, survival knife, small hatchet, short range radio, Hard-shell backpack from NG-X67. |
Damage: 5d6+3 or 3d4x10 M.D. |
Payload: 240 shots using a portable generator, which regenerates 8 shots per hour. Can also be directly linked to a vehicles power supply (Nuclear or Solid-Ox) giving it a virtually unlimited payload. |
Weight: Laser cannon - 40 lbs., Portable generator - 30 lbs. |
Last edited by Victor Singer on Mon Oct 22, 2018 3:40 pm, edited 47 times in total. |
Victor Calvin Singer was born to Robert and Karen Singer, he also has a sister named Christine who is just a year younger. His family lives in the Manistique Imperium where Victor was raised. His father works in a Northern Gun assembly plant that just so happens to turn out final assemblies of robot vehicles and power armor suits, interestingly enough his sister also works at the plant these days, though she began there after Victor left for the Army. From an early age he was fascinated by the robot vehicles and power armor that has dad built. Mainly it was the smaller power armor suits that caught his attention, how a soldier could go into combat in such a suit and take out a much larger, more heavily armored robot or a 20’ tall supernatural monster was exciting to him. So, when he turned 18 it seemed only natural that he join the Army and apply to be a PA pilot. With his reflexes plus his almost obsessive knowledge of power armor, he became an excellent soldier…at least on paper and tests. |
Somehow, during his 4 years of service, Victor was always assigned or re-assigned to a unit that was in the single most boring and inactive post. He has been in only 4 minor fire fights and even than his squad was either on mop-up duty or just on standby in case things went sideways. So, once his 4 years of enlistment was up, Victor applied for private military contractor status, purchased a Blue Boy power suit and moved on. He has done half a dozen solo jobs, but he’s found it is much more difficult to carry out a mission when you don’t have a squad at your back. This lead him to contact some old friends back home about any work they might know of. One friend in particular responded, Mindy Corsair. She in turn suggested he get hold of Emerald Ecks and after a long conversation about her brother Royal and his...life lessons...Emerald convinced Victor to reach out to Royal. Apparently her brother had for some time now been running a mercenary unit out of MercTown and she thought they might be hiring. Victor has misgivings about Royal, as he wasn't the nicest guy when they were kids, but Victor knows and trusts both Emerald and Mindy. In particular Mindy's word means most to him since she was not a fan of Royal when they were younger...now she seems to be genuinely proud of the guy. Victor figures it couldn't hurt to go and meet up with Royal and see what is what. So, he contacted Royal and the two set up a meet in MercTown. Now, looking at the city of MercTown from a nearby hilltop, Victor hopes his trek here means work...preferably paying work. |
Last edited by Victor Singer on Sat Jun 04, 2016 10:36 am, edited 6 times in total. |
Used T-42 Commando = 38,000 (pg. 38 of Triax & NGR) Note: Has only 45 MDC, -5% Prowl (only to prowl, other movement is fine). What Victor didn't notice is that the legs have some bad repair to the fabric lining, it crinkles and cracks as the wearer moves. What he did notice is that the suit has been outfitted with four concealed pockets. One on the back is useful for a medium or smaller handgun. Two are on the inside of thighs are are suitable for hiding papers or the like (such as maps). The third is on the inside of the chest, it's only accessible when the suit is off. It can hold a larger volume of flat stuff compared to the thighs. |
Used NG-WJ10 Speedpack (electric) = 28,000 (pg. 193 of Northern Gun 2) Note: Has only 28 MDC, gets only 750 miles per charge, 12 years old. Otherwise in great working order. It would take rebuilding the housing almost completely to get the MDC back. Installing a new battery would restore the range to 800 miles. |
Victor will look over several junkyards for this and will ask each of the owners to keep an eye out for the launcher or see if any of them will place an order for one, so to speak. |
None are available. Most of the dealers in Merctown are unfamiliar with the NGR military hardware. The Super Trooper is rare outside the military even in Europe. By the third junkyard the dealer tells Victor he got a call from Kraus telling him to not deal with Victor. |
1d8 = 4: Receive a +2D6 Attribute Boost to P.S. |
(1) Receive a +2D4 Attribute Boost to M.E. |
+2d4 = 4 to M.E. |
+1d4 = 3x10=30 to P.P.E. |
NOTE: No point in rolling the sub table on the next two, since both are on the same sub-table and Victor already has 2 of the 4 on said sub-table. |
(1) Receive a +2D4 Attribute Boost to P.P. |
HomeLight runs the stats on each of the 134 agents in Redding so that you can select the top performing real estate agents. The top 3% Redding agents work with 487 homes and get them sold in 53 days. |
Redding, CA has 134 active real estate agents. The average real estate agent in Redding sells about 365 homes and each home spends about 80 days on Redding's housing market. Let's see how the top 3% perform in comparison. |
In contrast with the average Redding real estate agent, the top seller's agents sell 310.17 more homes, close deals 26.39 days faster, and earn sellers an extra 9.1% on each home sale. |
When compared against the average real estate agent, the top Redding buyer's agents move about 277 properties and save buyers $24,823 on their home purchases. |
When is the right time to hire a real estate agent in Redding? |
It's going to depend on the temperature of the Redding housing market but we generally recommend that you hire a real estate agent as soon as you're thinking of selling your home. Generally speaking, that's anywhere from 3 to 6 months prior to your desired move date. |
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