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Pneumatosis intestinalis is diagnostic of
.Necrotising enterocolitis is an acquired inflammatory disease commonly seen in infants and newborn but occasionally can occur in children and adults. It ismore commonly seen in premature babies. It is more common in formula fed babies than breast bed babies. Reduced gut flora make virulent pathogens to act and cause s...
2
Ileal perforation
Necrotizing enterocolitis
Meconium ileus
Colonic aganglionosis
Surgery
G.I.T
2d38b3e9-574d-4614-90ee-06933b231ae9
single
True about MRI/CT appearance of lateral meningocele:
C i.e. Widened neural foramen - Lateral meningocele is non solid, CSF containing leptomeningeal outpouching through widened neural foramen usually into paraspinal, intrathoracic spaceQ. And it is generally associated with spinal deformities like, posterior (dorsal) scalloping, erosion of pedicles, thinning of neural ar...
3
Solid dural masses
Usually outside the spinal canal
Widened neural foramen
Generally there is no spinal cord compression & deformity
Radiology
null
64d49c57-9496-49bc-a037-20087d2a653f
multi
The sequence in a long chain of protein is identified by
"A major use of RFLPs is in the definition of inherited diseases in which the functional deficit is unknown. RFLPs / SNPs can be used to establish linkage groups, which in turn, by the process of chromosome walking, will eventually define the disease locus. In chromosome walking, a fragment representing one end of a lo...
2
Restriction fragment length polymorphism (RFLP)
Chromosome walking
Leucine Zipper
SSOP
Biochemistry
null
51633482-92ea-4a13-86ba-25dc86f2447d
single
Cyclic GMP is the second messenger of:
C i.e. Insulin
3
Growth Hormone
Follicle Stimulating Hormone (FSH)
Insulin
Thyroxin
Physiology
null
24159036-886b-4c2d-be10-21b40436b621
single
Which of the following does not cause biliary tract obstruction ?
Pathogenesis and clinical features of ankylostoma duodanale Infective agent: filariform larvae Poal of entry: skin The worm causes hookworm disease in man characterized mainly by anaemia. (refer pgno:144 baveja 3 rd edition)
2
Ascaris lumbricoides
Ankylostoma duodenale
Clonorchis sinensis
Fasciola hepatia
Microbiology
parasitology
c2930ca4-0659-482e-95ab-fc34ea0ad6b3
single
IgA-nephropathy is seen in:
Answer is B (Mesangioproliferative glomerulonephritis):
2
Membranous glomerulonephritis
Mesangioproliferative glomerulonephritis
Focal glomerulonephritis
Cresentic glomerulonephritis
Medicine
null
0423d4de-a5f6-4218-aa44-2843ca2a317a
single
Testes completely descend in the scrotum by the: DNB 09
Ans. End of 9th month
3
End of 7th month
End of 8th month
End of 9th month
After bih
Forensic Medicine
null
7a1968e6-6884-4d96-bc46-915ae37661b0
single
Pt with recurrent diarrhoea, pseudopolyp, lead pipe appearance on Ba enema has -
null
1
Ulcerative colitis
Crohn's disease
Irritable bowel syndrome
Short bowel syndrome
Surgery
null
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single
The risk factor association of pancreatic cancer was studied in a case control study. The values of the odds ratio and the confidence interval for various risk factors are as below: Risk factors Odds ratio 95% confidence limit A 2.5 1 - 3 B 1.4 l .1 - 1.7 C 1.6 0.9 -1.7 Which is true:
Risk B has the strongest association [Ref: http://www.thedoctorsdoctorcom/labtests/statistics.htm Odds ratio is a measure of the strength of the association between risk factor and the outcome. It is used to assess the risk of a paicular outcome (or disease) if a ceain factor (or exposure) is present. The odds ratio is...
2
Risk A has strongest association with pancreatic cancer
Risk B has the strongest association
Risk C has the strongest association
All three are equally associated
Social & Preventive Medicine
null
491847e2-7357-4994-8f46-b2cd8798f25d
multi
Drug of choice for status epilepticus is: September 2011, March 2013
Ans. C: Lorazepam Intravenous Lorazepam is now the treatment of choice for controlling seizures in status epilepticus Status epilepticus/SE It is a life-threatening condition in which the brain is in a state of persistent seizure. Definitions vary, but traditionally it is defined as one continuous unremitting seizure l...
3
Valproate
Phenytoin
Lorazepam
Carbamazepine
Pharmacology
null
770b345e-07eb-4a76-9922-f0720dc5b95d
single
Koplik spot true is ?
Ans. is 'a' i.e., Pathognomic of measls Measle Caused by RNA virus. Highly contagious droplet spread from secretion of nose and throat 4 day before and 5 days after rash. Secondary attack rate >90% in contact. Prodromal phase - characterized by fever, rhinorrhea, conjuctival congestion and dry hackig cough. Koplik spot...
1
Pathognomic of measls
Present on buccal mucosa opposite P' molar
Always present
All of above
Pediatrics
null
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multi
Complication of measles are all except -
Ans. is 'd' i.e., Panereatitis
4
Myocarditis
Appendicitis
SSPE
Pancreatitis
Pediatrics
null
b750e6df-7c6f-4d2b-b87e-f2d065d93868
multi
True about histology in infilterating lobular breast carcinoma-
Ans. is 'a' i.e., Single file patterno Histological hallmark of invasive lobular breast carcinoma is pattern of single infilterating tumor cells often only one cell in width or in loose clusters or sheets.
1
Single file pattern
Pleomorphic cells in sheets
Cribriform pattern
Pin wheel pattern
Pathology
null
1646f988-14a8-4aec-b83d-f62255a4730e
multi
According to AHA/ACC all the surgeries are associated with low risk requiring no preoperative cardiac testing in patients with known coronary aery disease except-
Risk stratification Procedure examples Vascular (repoed cardiac risk >5%) Aoic and other major vascular surgery Peripheral vascular surgery Intermediate risk (repoed cardiac risk 1%-5%) Intraperitoneal and intrathoracic surgery Carotid endaerectomy Head and neck surgery Ohopedic Surgery Prostate surgery Low risk (repoe...
3
Cataract surgery
Endoscopic procedure
Prostate Sx
Breast Sx
Anaesthesia
Pre Anesthetic Evaluation
198bc3c2-5bc0-4de7-a43f-718119ae4a4a
multi
Estimation of the degradation products of the cross- linked fibrin fibers in DIC can best, specifically, and accurately be done by which of the following tests?
Ans. b (D-dimer assay) (Ref. H - 18th/ch. 116)The quantitative plasma D-dimer ELISA level is elevated (>500 ng/mL) in more than 90% of patients with Pulmonary Embolism, reflecting plasmin's breakdown of fibrin and indicating endogenous (though clinically ineffective) thrombolysis. However, the D-dimer assay is not spec...
2
Fibrinopeptide assay
D-dimer assay
Euglobin lysis test
Coombs test
Pathology
Blood
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multi
A 25 Yr old lady presents with spontaneous nipple discharge of 3 months duration. On examination the discharge is bloody and from a single duct. The following statements about management of this patient are true except
Treatment Treatment must firstly be to exclude a carcinoma by occult blood test and cytology. Simple reassurance may then be sufficient but, if the discharge is proving intolerable, an operation to remove the affected duct or ducts can be performed (micro-dochectomy). Ref: Bailey and love 27th edition Pg no : 865
2
Ultrasound can be useful investigation
Radical duct excision is the operation of choice
Galactogram, though useful is not essential
Majority of blood stained nipple discharges are due to papilloma or other benign condition
Anatomy
Endocrinology and breast
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multi
A 32 years old lactating mother presented with a painful, palpable lump in her left breast. The most appropriate investigation to diagnose her condition would be:
Ans is 'b' i.e. USG The presentation of a lactating female with painful palpable breast lump is highly suggestive of breast abscess. Ultrasound would be the most useful investigation to diagnose the condition and in delineating the required extent of the drainage procedure. Mammography would be non specific for breast ...
2
Mammography
USG
MRI
SPECT
Surgery
null
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single
Deformity most commonly seen in primary osteoahritis of knee joint
In knee joint osteoahritis, medial joint space is affected earliest and causes assymetrical joint space narrowing This results in varus deformity Refer: maheswari 9th/e p 420
3
Genu valgum
Genu recurratum
Genu varus
Procurvatum
Anatomy
Joint disorders
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single
The level of alpha fetoprotein is raised in all of the following except.
Ans. is 'd' i.e. Dysgerminoma Elevation of a feto protein is not seen in dysgerminoma. It may sometimes show elevation of bHCG.Raised a fetoprotein is seen in:Neoplastic conditions:Liver cancerGerm cell tumours of testis (non seminomatous)Yolk sac tumours*Embryonal carcinoma*Non neoplastic conditions:Cirrhosis*Pregnanc...
4
Cirrohosis of liver.
Hepatocellur carcinoma
Yolk sac tumor
Dysgerminoma
Medicine
Liver
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multi
Hemagglutinin and neuraminidase are found in:
Ans. C. Influenza virusHemagglutinin is for attachment to sialic acid/mucin receptors and neuraminidase/mucinase is for release/elution.
3
Norovirus
Hantavirus
Influenza virus
Rubella virus
Microbiology
Virology
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single
A 3-year-old boy is admitted to the hospital with signs of acute renal failure. Radiologic studies reveal that the boy has bilateral masses involving both kidneys. Examination of biopsy material confirms the diagnosis of Wilms tumor. Which of the following gene mutations is the most common in Wilms tumor?
Wilms tumor is a kidney malignancy that usually occurs in children. It has recently been shown that it can be caused by mutations in the WT1 gene, behaving according to Knudson's two-hit model for tumor suppressor genes.
1
The gene responsible for WT1
The gene responsible for HGF
The gene responsible for VEGF
The gene responsible for GDNF
Anatomy
Abdomen & Pelvis
4386592b-58f8-48f6-b34a-384a2d30054d
multi
Glyconeogenesis is
Glyconeogenesis Synthesis of glycogen from non-carbohydrate precursors This pathway is the same as gluconeogenesis, but the last step is different i.e. In glyconeogenesis, glucose-6-Phosphate directly enters glycogen synthesis. So glucose-6-phosphatase step is not required. Glycogenesis -Synthesis of glycogen from gluc...
4
Synthesis of glucose from non-carbohydrate sources
Synthesis of glycogen from glucose
Synthesis of glucose from glycerol
Synthesis of glycogen from non-carbohydrate sources
Biochemistry
Glycogen
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single
ECT is contraindicated in
Raised intracranial pressure is the only absolute contraindication for ECT
4
Pregnancy
Seizure disorder
Mania
Raised Intracranial pressure
Anatomy
All India exam
3495fa94-06e0-4c85-91c6-a383611a4e1e
single
Which of the following is used for treatment of myopia:
Ans. Excimer laser
2
Nd: YAG laser
Excimer laser
Argon laser
Holmium laser
Ophthalmology
null
00b83087-9e98-45e8-9bae-4f7b4e5b1bfb
single
Which of the following is the preformed toxin involved in mechanism of allergic rhinitis ?
Ans. is 'a' i.e., Histamine
1
Histamine
Leukotriene
TXA2
PGD2
Pathology
null
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multi
Term gestation patient with critical aortic stenosis presents to the labor, and her cervix is 6cm dilated. Your approach in treatment of patient includes all except
Pregnant woman with critical aortic stenosis needs intensive monitoring during labor. So pulmonary artery catheterization is helpful. Maintaining intravascular volume and cardiac output is important to decrease chances of hypotension and hemorrhage.
4
Provide opiod epidural analgesia.
Limit activity.
Do pulmonary artery catheterization.
Restrict i.v fluids to decrease cardiac preload.
Gynaecology & Obstetrics
null
38f552e6-10d6-4ddb-99c6-95c9e4fb91d6
multi
Kiel bone is: Xenograft Allograft Treated by detergent, sterilized and freeze dried. Ox or calf bone denatured with 20% H2O2, acetone and sterilized.
null
3
1&3
2&3
1&4
2&4
Dental
null
eb6ab973-bed5-4977-acd7-8bf94f9e4571
multi
A screening test has 90% sensitivity and 90% specificity. Diseased population is 10% What is PPV ?
Sensitivity = 90% Specificity = 90% Prevalence = 10% (i) Formula for PPV according to Bayes Theorem,
3
PPV 80%
PPV 85%
PPV 90%
PPV 95%
Social & Preventive Medicine
null
38dc9281-526f-44bc-b66f-4a05932b119c
single
Which stage of syphilis is most contagious ?
null
2
Primary
Secondary
Early latent
Later latent
Dental
null
81f56b93-bfb6-41c8-8a1a-b7fa784375ae
single
Di collar is seen in:
Fire arm entry wound
1
Fire arm entry wound
Fire arm exit wound
Both of the above
None of the above
Forensic Medicine
null
ced38f0d-2b14-4400-ae1c-9fbdf80d5b85
multi
Which of the following have been implicated in the pathogenesis of ovarian hyperstimulation syndrome?
Ovarian Hyperstimulation SyndromeOHSS is a medical complication that is both completely iatrogenic and unique to stimulatory infeility treatment.Its symptoms are the result of ovarian enlargement and fragility, extravascular fluid accumulation, and intravascular volume depletion.Proposed mechanisms for the characterist...
1
VEGF
hCG
EGF
FGF
Gynaecology & Obstetrics
Infertility
f7369091-1cf3-4e1b-bac5-05f3532d8351
single
'Arrest of labour' is defined as Failure of the head of the fetus to descend within___________.
Ans- B Note- 'Arrest of labor' is defined as Failure of the head of the fetus to descend for 3hours among primiparas and 2 hours among multiparas without an epidural analgesia +1 hour each if epidural analgesia is administered.
2
1 hour
2 hours
3 hours
4 hours
Unknown
null
ea7c8a9f-ebbf-48d4-9753-a62e681126c3
single
Which of the following is true about viral antibodies?
Ans. c. Formed against viral surface proteins (Ref: Harrison 19/e 214e-8, 18/e p1439)Viral antibodies are formed later than interferon and significant levels are seen after one week and are directed against the viral surface proteins.'Resistance to viral infections is initially provided by factors that are not virus-sp...
3
Appear before interferon
Formed against viral nuclear acid
Formed against viral surface proteins
Maximum levels are seen writhin one week
Microbiology
Properties of Virus
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multi
Saliva dribbling from mouth is characteristic of:
B i.e. Antemoal hanging Ligature mark is a type of pressure/ pressure/ imprinted/ contact/ patterned - abrasionQ. In cheese cutter method, a narrow wire is used. The cause of death in judicial hanging is fracture - dislocation usually at C2 - C3 or C3 - C4 veebraeQ. Dribbling of saliva is a sure sign of hanging having ...
2
Postmoem hanging
Antemoem hanging
Suicidal hanging
Homicidal strangulation
Forensic Medicine
null
2bb622fc-4279-4c98-8ef1-32954e4841b9
single
The best mental attitude for denture acceptance:
Mental attitude Dr. M.M. House (1950) classified patients as philosophical, exacting, indifferent and hysterical. This is the most widely used classification. Class I: Philososphical patients They are rational and composed in difficult situations. They desire treatment for maintenance of health and appearance and acce...
2
Exacting
Philosophical
Hysterical
All of the Above
Dental
null
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multi
A 43 year-old executive presents to a physician with chronic symmetric polyarthritis involving the knees. The man gives a history of having developed an extensive rash after a deer-hunting trip several years earlier. He recalls that he felt 'sick' at that time and developed knee pain that prevented him from climbing st...
A ns. D. SpirocheteLyme's disease: Caused by Borrelia burgdorferi, a spirochete.a. Transmitted by bite of Ixodid ticksb. Natural reservoir: Deer, rodents & other animalsc. IP: 3-30 daysd. 3 stages, stage of local infection, stage of disseminated infection & stage of persistent infection in the form of oligoarthritis, e...
4
Fungus
GN cocci
GP cocci
Spirochete
Microbiology
Virology
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multi
Codman's triangle is feature of?
Ans. A. Osteosarcoma. (Ref. Pathology Robbings 8th/Table 21-2).a large, destructive, mixed lytic and blastic mass with indistinct infiltrating margins. The tumor frequently breaks through the cortex and lifts the periosteum, resulting in reactive periosteal bone formation ("Sun-burst" or 'Sunray' periosteal reaction). ...
1
Osteosarcoma
Osteochondroma
Osteoid osteoma
Chondrosarcoma
Radiology
Skeletal System
47a3c3b1-1db4-40e8-a7bf-cd202f9a2d00
single
Drug used to perform stress ECHO -
Stress echo has the same technique used to acces the hea function at rest with a stressor as exercise or dobutamine infusion. It can cause emergence of regions of akinesis or dyskinesis not present at rest.IT Is primarily indicated to confirm the suspicion of ischaemic hea disease and to estmate its severity. Response ...
2
Thallium
Dobutamine
Adrenaline
Adenosine
Radiology
Cardiovascular system
008c09d6-d56b-49df-82e6-ae9f70b1ddf4
multi
Thiopentone is C/I in –
Thiopentone is contraindicated in acute intermittent porphyria. It is contraindicated in status asthmaticus but not in simple asthma.
1
Acute intermittent porphyria
Bronchial asthma
Both
null
Anaesthesia
null
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multi
Koebner's phenomenon is seen in all EXCEPT:
Ans. B. Pemphigoida. Koebner's phenomenon is seen in:i. Psoriasisii. Wartsiii. Lichen planusb. Koebner's phenomenon is also called isomorphic response.
2
Psoriasis
Pemphigoid
Warts
Lichen planus
Skin
Papulosquamous Disorders
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multi
During surgical exploration for hydatid cyst of the liver, any of the following agents can be used as a scolicidal agent except
.
2
Hypeonic sodium chloride
Formalin
Cetrimide
Povidone iodine
Anatomy
G.I.T
1e25b69e-6425-4e0c-a5c5-574677947aba
multi
Which of the following is used as an indicator for plasma sterilization?
For determining the efficacy of moist heat sterilization, spores of Bacillus stearothermophilus are used as the test organism. This is a thermophilic organism with an optimum growth temperature of 55-60oC and its spores require an exposure of 12 minutes at 121oC to be killed. Ref: Textbook of Microbiology by Ananthanar...
2
Bacillus subtilis
Bacillus stearothermophilus
Bacillus pumilus
Clostridium tetani
Microbiology
null
d615b39d-33b0-4cdb-94f8-174290db1440
single
Sadism is?
Ans is 'a' i.e. Painful sexSadism:o Sexual gratification is obtained or increased from acts ofphysical cruelty or infliction ofpain on one's partner.o It is seen more commonly in men. To obtain sexual gratification, the sadist may bite, beat, whip, produce cuts on the victim, etc.Other options:o Having intercourse with...
1
Painful sex
Having intercourse with an animal
Anal intercourse
Sexual intercourse with dead bodies
Forensic Medicine
Sexual Offenses and Dowry Death
57d44360-c7be-410b-a8df-3d4eb4c55029
single
The preferred treatment option for primary syphilis is -
Ans. is 'a' i.e.,Injection benzathine pencillin 2.4 million units IM single dose
1
Injection benzathine pencillin 2.4 million units IM single dose
Injection benzathine pencillin 2.4 million units IM once a week for 3 weeks
Cap. doxycycline 100 mg orally twice a day for 2 weeks
Tab. azithromycin 2 gm single dose
Pharmacology
null
43d3d05e-f694-4e9f-bf3f-44c2b60ad818
multi
The only excitatory neuron in the cerebellar coex is
Granular cells are the only excitatory cells of cerebral coex, use glutamate as neurotransmitter, their axons from parallel fibres Ref: Ganong 25th ed/page 248
4
Purkinje cell
Basket cell
Golgi cell
Granular cell
Physiology
Nervous system
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single
What is the 02 content of saturated aerial blood?
One gram of hemoglobin can bind with a maximum of 1.34ml of oxygen. Thus 100ml of blood with hemoglobin level of 15 gm% can carry 1.34 x 15 = 20.1ml of oxygen. However due to the presence of various physiological shunts only 95% of Haemoglobin is available for carrying oxygen. Therefore practically 100 ml of aerial blo...
3
11.2 ml/100 ml
14.5 ml/100 ml
19.4 ml/100 ml
21.3 ml/100 ml
Physiology
null
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single
Medial wall of Orbit is formed by all except
Medial wall of the Orbit is formed by:From before backwards1. Frontal process of maxilla2. Lacrimal bone3. Orbital plate of ethmoid4. Body of sphenoidReference: Chourasia; 6th edition; 29th page
1
Lesser wing of Sphenoid
Frontal process of Maxilla
Lacrimal bone
Orbital plate of Ethmoid
Anatomy
General anatomy
07976c1a-fad5-4c60-b462-25fa98b76f40
multi
Intermediate filaments (IFs) help link adjacent sarcomeres together in skeletal muscle. Which of the following proteins is an intermediate protein used diagnostically in pathologic cases to indicate muscle origin?
Desmin is the intermediate filament (IF) protein that polymerizes to form the desniin IF of skeletal muscle. It is found in smooth, skeletal, and cardiac muscle. The desmin IF links desmosomes of cardiac muscle, thus serving to stabilize cell junctions. Actin is the protein of microfilaments-the smallest diameter filam...
2
Actin
Desmin
Actinin
Clathrin
Physiology
null
a5c22aca-7200-446e-bc0c-9d5b4e1668ca
multi
What is the marker for endodermal sinus tumor?
Ans. is 'c' i.e., AFP * Endodermal sinus tumor (yolk sac tumor) is positive for AFP and a 1-antitrypsin. * The effects of biological changes caused by radiation can be categorized into 1) Stochastic effects # A stochastic effect is one where the probability of the effect occurring is governed by the law of chance. Thus...
3
CA-125
HCG
AFP
Inhibin
Unknown
null
79ab08ce-8724-4c58-91cf-10c81fc8487c
single
All of the following are clinical features of Cushing's syndrome EXCEPT:March 2004
Ans. B i.e. MenorrhagiaMenstrual irregularities may be seen in 80% of patients of Cushing syndrome
2
Insulin resistance
Menorrhagia
Violaceous striae
Centripetal obesity
Pathology
null
a028c8c6-dd6d-4619-bdf5-fce9c262dcfb
multi
Crown formation of all permenent teeth except third molars is completed between
null
1
Birth to 8 years
Birth to 12 years
Birth to 6 years
6 years to 12 years
Dental
null
f146b765-6515-40fd-bbab-07552acccedb
multi
Paton's lines are peripapillary folds which result due to
Papilledema leads to CIRCUMFERENTIAL PERIPAPILLARY RETINAL FOLDS known as Paton's Lines.
2
Optic neuritis
Papilledema
Anterior ischemic optic neuropathy
CRAO
Ophthalmology
Neuro Ophthalmology
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single
True about secondary immune response is -
if an individual who is actively immunized against an antigen experiences the same antigen subsequently, the immune response occurs more quickly and abundantly than during the first encounter. This is known as a secondary response. Reference : Anathanarayan & paniker's 9th edition, pg no:81,82 <\p>
3
Long latent period
Usually of low titire
Antibodies appear in sho time
Persist for long
Microbiology
Immunology
f9107c82-a050-4bc0-9b43-46ebe08433b2
multi
All are features of Alagille syndrome, EXCEPT:
Syndromic paucity of interlobular bile ducts (Alagille syndrome) is the most common form of familial intrahepatic cholestasis. Chronic cholestasis affects 95% of patients. Peripheral pulmonic stenosis is observed in approximately 90%. Veebral arch defects are seen (e.g., butterfly veebrae, hemiveebrae, and a decrease i...
2
Posterior embryotoxon
Hepatocellular jaundice
Peripheral pulmonary stenosis
Butterfly veebrae
Medicine
null
27dae80c-765d-4dcc-9875-7c05b4325a24
multi
Idiosyncracy is known as to have
null
1
Genetic component
Psychological component
Physiological component
Nutritional component
Pharmacology
null
604d35ec-4818-4b71-8e0c-15f88b38c381
single
All are true about Menetrier disease except:
Ans. (b) Decreased mucus productionRef: Sabiston 19th Edition, Page 1222* Acquired premalignant disease showing brain like cerebriform mucosa on gross examination.* Pathological examination shows: Foveolar hyperplasia and absent parietal cell* Massive gastric folds appearing like brain is most common in fundus and body...
2
Excessive protein loss
Decreased mucus production
Acquired, premalignant condition
H. pylori is a predisposing factor in adults
Surgery
Stomach & Duodenum
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multi
Hydrogenation of fatty acid is ?
Ans. is 'c' i.e., Addition of hydrogen to unsaturated fatty acidAddition of hydrogen atoms to unsaturated fatty acid refers to hydrogenation. It reduces the number of double bonds in the unsaturated fats.Hydrogenation of unsaturated fats in the presence of a catalyst (nickle) in known as "hardening", because it conves ...
3
Hydrolysis by Alkali
Auto-oxidation of PUFA
Addition of hydrogen to unsaturated fatty acid
Addition of hydrogen to saturated fatty acid
Biochemistry
null
a04e727b-e6ed-41a0-8b76-e6f70991b1cb
single
Hormonal stimulation of the formation of second messenger inositol 1, 4, 5-triphosphate (IP3) quickly leads to the release of which other intracellular messenger?
Ans. is 'c' i.e., Calcium o 1P3 mobilizes Ca'from intracellular organelles and increases cytosolic Ca' and then Ca" acts as third messenger.
3
Cyclic AMP
Prastaglandin
Calcium
Leukotriene
Pharmacology
null
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single
Plasma retinol value which is considered as marginal in children is
The plasma retinol value of 0.7 to 1.05 mmol/L is considered to be marginal. Values more than 1.05 mmol/L are considered to be adequate for children. Values between 0.35 to 0.7 mmol/L are considered to be deficient. If the value is less than 0.35 mmol/L, it is considered to be very deficient. Reference: GHAI Essential ...
3
0.25 to 0.35 mmol/L
0.35 to 0.7 mmol/L
0.7 to 1.05 mmol/L
1.05 to 1.45 mmol/L
Pediatrics
All India exam
3c180835-06cc-416a-9cae-ae862bbfb93e
single
Following features may be seen in cold injury of neonates except -
Ans. is 'b' i.e., Uncontrolled Shivering "Neonates Respond by Non-shivering thrmogenesis".
2
Bradycardia
Uncontrolled shivering
Scleroma
Metabolic acidosis
Pediatrics
null
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multi
WHICH STATEMENT IS TRUE ABOUT CAFFEY&;S DISEASE IS ?
CAFEYS DISEASE : Infantile Coical Hyperostosis is a rare disease of infants and children. Usually stas during the first few months of life with painful swelling over the tubular bones and mandible Child may be feverish and irritable,refusing to move the affected limb X-rays characterically show periosteal new-bone form...
2
Renal osteodystrophy
Infantile coical hyperostosis
Osteomyelitis of jaw in children
Chronic osteomyelitis in children
Orthopaedics
Pediatric orthopedics
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multi
All the following are true regarding blood supply to the kidney, except:
Ans. (b) It is a type of portal-circulationRef: Snell's 7th Edition, Page 283Renal artery/ Venous system:* Right renal artery longer than left* Renal artery divides into 5 near hilum.* They are end arteries.* Left renal vein longer than Right* Stellate veins drain superficial zone of kidney cortex.* Left kidney is pref...
2
Stellate veins drain superficial zone
It is a type of portal-circulation
The renal artery divides into five segmental arteries before entering the hilum
Its segmental arteries are end-arteries
Surgery
Kidney & Ureturs
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multi
Fogay's catheter is used for
Fogay catheter is like a ureteric catheter, with a balloon tip and is introduced until it is deemed to have passed the limit of the thrombus.The balloon is inflated and the catheter is withdrawn slowly with the clot.Ref: Bailey and love 27e pg- 955
3
Drainage of urinary bladder
Parenteral hyperalimentation
Removal of embolus from blood vessels
Ureteric catheterization
Microbiology
All India exam
4e567c0b-80a2-40aa-b6f0-b52c69489137
single
Maternal to child transmission of HIV is prevented by
HIV infected mother can transmit the virus to fetus''infant during pregnancy, during delivery or by breastfeeding, Early diagnosis and antiretroviral therapy to mother and infant significantly decrease the rate of intrapartum and perinatal transmission (Vertical transmission) of HIV infection. Zidovudine treatment of H...
1
Nevirapine
Lamivudine
Didanosine
Abacavir
Microbiology
null
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single
Superficial corneal vascularization is caused by-
The clinical picture of interstitial keratitis can bedivided into three stages: initial progressive stage,florid stage and stage of regression. Florid stage. In this stage eye remains acutelyinflamed. Deep vascularization of cornea, consistingof radial bundle of brush-like vessels develops. Sincethese vessels are cover...
4
Contact lens
Graft rejection
Chemical burn
Interstitial keratitis
Ophthalmology
Cornea and sclera
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single
Annexin V is a marker of -
Ans. is 'a' i.e., Apoptosis
1
Apoptosis
Necrosis
Aherosclerosis
Inflammation
Pathology
null
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single
All have antioxidant propey except
Although numerous biologically active molecules exist as glycosides in nature, information on the activity, stability, and solubility of glycosylated antioxidants is rather limited to date. In this work, a wide variety of antioxidants were glycosylated using different phosphorylase enzymes. The resulting antioxidant li...
3
Catalase
Glutathione peroxidase
Phosphorylase
Superoxide dismutase
Biochemistry
Enzymes
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multi
Gyromagnetic propey of proton is seen in -
MRI is based on gyromagnetic propey on protons. Defined as the ability of protons in the body to absorb and emit radio waves, when the body is placed in strong magnetic field.
1
MRI
CT
PET scan
USG
Radiology
Fundamentals in Radiology
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single
Which of the following factors determines whether a patient develops acromegaly or gigantism?
null
2
Sex
Age at onset of the tumor
Amount of available calcium
Degree of function of the tumor
Medicine
null
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single
True about adenocarcinoma of lung -a) More common in femaleb) Smoking is not associated withc) Central cavitationsd) Upper lobe involvement is most commone) Peripheral involvement
Adenocarcinoma of lung Adenocarcinoma is the most common lung cancer, overall. Also the most common type of lung cancer in women and nonsmokers. This is a malignant epithelial tumor with glandular differentiation or mucin production by tumor cells. Growth pattern may be any of the following Acinar       Bronchioalve...
3
abc
bcd
abe
acd
Pathology
null
1b4a5d33-ee54-445f-8d23-9253ab3e2a5b
multi
In case of PSGN complication commonly seen are all except :
PSGN complications are – Acute renal failure Chronic glomerulonephritis Chronic renal disease Congestive heart failure or pulmonary edema End-stage renal disease Hyperkalemia High blood pressure (hypertension) Nephritic syndrome
4
LVF
Hypertensive encephalopathy
Hyperkalemia
Bleeding diathesis
Unknown
null
137b098b-cea8-455b-8637-0f13d8a441cd
multi
Which of the following is a T-cell marker?
Important cells with their CD marker are:-
2
CD45
CD8
IL3
CD19
Pathology
null
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single
Site of bleeding after cataract surgery is:
Posterior ciliary vessels REF: Phacoemulsification in difficult and challenging cases by Luis W. Lu, I. Howard Fine- Page 173 Expulsive choroidal haemorrhage is a rare and dreadful complication of cataract surgery that usually results in either loss of vision or loss of the eye. It is most frequently associated with ca...
4
Anterior choroidal vessels
Posterior choroidal vessels
Anterior ciliary vessels
Posterior ciliary vessels
Ophthalmology
null
ff753052-a770-4c67-a738-e8cc43977b09
single
Fulminant Hepatitis E is typically seen in:
Answer is A (Pregnant women): Fuhninant Hepatitis E is typically seen in pregnant women especially in the last trimester. 'A unique feature of Hepatitis E virus is the clinical severity and high case fatality rate (20-40%) in pregnant women, especially in the last trimester ofpregnancy'. - Park 'Hepatitis E can lead to...
1
Pregnant women
Infants
Adolescents
Malnourished males
Medicine
null
ff744e21-61fd-47d3-8f7d-aaba0eefa047
multi
IPC for dowry death is?
Ans. is 'b' i.e., 304 Bo 304-BIPC: Dowry death : 10 years of imprisonment which can extend to life.o 498-A IPC: Punishment for cruelty by husband or his relatives.Dowry deatho In some cases newly married girls are abused, harassed, cruelly treated and tortured by the husband, in-laws and their relatives for or in conne...
2
304 A
304 B
375
376
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
785b9faa-8a13-47a8-b7c7-d6c3e14699a4
single
Bronchopneumonia complication in measles is due to -
null
4
Aspiration
Sinusitis
Bronchiolar obsturction
Immuno-modualtion
Medicine
null
8f68a3e7-d0e6-4b46-8927-5c5f0134ac81
single
All are true about N2O except
Stored in cylinder as gas It is stored as a liquid in the cylinder.
3
Colour of cylinder is blue
Priestly was the first to prepare it
Stored in cylinder as gas
It is prepared by heating ammonium nitrate
Physiology
All India exam
b28e3bf5-b6de-419b-a998-71601bcfdebb
multi
A 48-years-old female suffering from severe menorrhagia (DUB) underwent hysterectomy. She wishes to take hormone replacement therapy. Physical examination and breast are normal but X-ray shows osteoporosis. The treatment of choice is:
null
3
Progesterone
Estrogen and progesterone
Estrogen
null
Gynaecology & Obstetrics
null
06826076-19fc-4b33-b2a6-8cb384364fe3
multi
Centromere near the end of chromosome
Acrocentric REF: Precid & Strachan Molecular genetics, page 49, 153, http://en.wikipedia.org/wiki/ CentromereCentromere positionsEach chromosome has two arms, labeled p (the shoer of the two) and q (the longer). The p arm is named for "petit" meaning `small'; the q arm is named q simply because it follows p in the alph...
1
Acrocentric
Metacentric
Submetacentric
Telocentric
Anatomy
null
c3ea38df-cfc7-4263-853f-368070ec02d8
single
During bilateral adrenalectomy, intra-operative dose of hydrocoisone should be given after
Steroids are not given pre-operatively because these patients are already hypercoisolemic. Instead hydrocoisone 100 mg IV is given after the removal of second hyperplastic adrenal gland
4
Opening the abdomen
Ligation of left adrenal vein
Ligation of right adrenal vein
Excision of both adrenal glands
Physiology
All India exam
1f5d87f2-269c-4ee0-96fb-012637dd29b7
multi
Karyotype of a patient shows the following, what is the clinical abnormality that is expected?
a. Gynecomastia with long thin limbs(Ref: Nelson's 20/e p 618, Ghai 8/e p 640)Given Karyotype is 47 XXY - Kilnefelters syndrome with Gynecomastia with long thin limbs as expected findings.
1
Gynecomastia with long thin limbs
Short stature with polydactyly
Webbed neck with widely spaced nipples
Rocker bottom feet
Pediatrics
Genetics And Genetic Disorders
072dc2dc-45f8-4731-8cf6-f3b3f1e9d6a1
single
Below is the chest Xray of a young male with cough. There is no known cardiac abnormality. With of the following is most likely to be true about the patient?
Ans. B. Patient is likely to be immunocompromised* Its typical bilateral perihilar consolidation and Reticulo nodular interstitial involvement, typical of PCP.* Mycoplasma infection not likely as mycoplasma radiographically produces fluffy opacities and those infiltrations of mycoplasma are not Perihilar. It is not lik...
2
Raised ACE levels likely
Patient is likely to be immunocompromised
Cold agglutinins will be positive
Occupational history of patient will give an important clue to the diagnosis
Radiology
Miscellaneous
5e0c27d1-b59b-4607-9044-172944b00761
multi
Factors which reduce breast milk production are all of the following EXCEPT?
Factors which | breast milk production: the thought, sight or sound of baby Factors which | breast milk production: Use of dummies, pacifiers Feeding bottles, formula feeding Sore or cracked nipples Lack of night feeding & inadequate emptying of breast.
1
Sound of baby
Use of pacifiers
Formula feeding
Lack of night feeding
Pediatrics
Breast Milk & Breast Feeding
5071f8de-11b9-459e-9733-865277a044c4
multi
Elevated AFP levels are seen in all of the following except-
TEXT BOOK OF PATHOLOGY HARSHMOHAN 6THEDITION PG NO 637,711,709 Two tumour markers widely used in the diagnosis, staging and monitoring the follow-up of patients with testicular tumours are: human chorionic gonadotropin (hCG) and alpha-foetoprotein (AFP). In addition, carcinoembryonic antigen (CEA), human placental lact...
4
Hepatoblastoma
Seminoma
Teratoma
None of the above
Pathology
General pathology
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multi
Lysogenic conversion is
Ref: PubMed* Lysogenic conversion is characterized by integration of the bacteriophage nucleic acid into the host bacterium's genome.* Once the genetic material of phage bacteria is introduced, the host bacterium continues to live and reproduce normally.* The genetic material of the bacteriophage, called a prophage, ca...
2
Integration of host bacterial nucleic acid to phage
Integration of phage nucleic acid to host bacteria genome
Bacterial mechanism to cause antigenic shift
Bacterial method to acquire resistance
Microbiology
General
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single
Position of fetus definition
(C) Oreientation of foetus in relation to pelvis before delivary# In obstetrics, position is the orientation of the fetus in the womb, identified by the location of the presenting part of the fetus relative to the pelvis of the mother. It is the position assumed by the fetus before the process of birth.
3
Vertex presentation before delivery
Breech presentation before delivery
Orientation of foetus in relation to pelvis before delivery
Orientation of womb in relation to pelvis before delivery
Gynaecology & Obstetrics
Miscellaneous (Obs)
8a0ad558-2313-44b3-9f73-448b274445c8
single
THUMB PRINT APPEARANCE in culture film smear is seen in
null
3
bacillus anthrax
brucella
Bordetella
clostridium welchii
Microbiology
null
3ca4ce0e-e640-448e-ad14-720cf3c9fff0
single
Variceal bleeding is best treated with
Bleeding esophageal varices Octreotide is often given as an infusion for management of acute hemorrhage from esophageal varices in liver cirrhosis on the basis that it reduces poal venous pressure, though current evidence suggests that this effect is transient and does not improve survival Ref Davidson edition23rd pg 7...
3
Vasopressin
Nitroglycerine
Octreotide
Desmopressin
Medicine
G.I.T
e2be079e-ed76-4450-b15a-3a9506baeae4
single
Rate of activation with slow expansion is
null
4
1 mm per day
1 mm for 3 days
1 mm for a month
1 mm per week
Dental
null
cd65d4a2-cab8-4714-b938-9647dabb27cd
single
A 3-year-old boy presented to the pediatrics ER with significant dehydration along with irritability, weakness and severe lethargy. His mother says he suffered from bloody diarrhea along with fever and abdominal pain 8 days ago. Lab findings, Anemia Deranged RFTs Thrombocytopenia Severe hyponatremia Leukocytosis. PT an...
This is a case of typical HUS. If history of diarrhoea would had been absent, the diagnosis would had been atypical HU for which FDA has approved eculizumab. Peripheral blood smear shows the presence of burr cells and schistocytes - suggestive of microangiopathic hemolytic anemia. Eculizumab Anti-C5 antibody Inhibits c...
2
Omalizumab
Eculizumab
Caplacizumab
Mepolizumab
Unknown
Integrated QBank
6f174bb3-190d-46d6-a690-7c398d654237
multi
Which of the following opioid should not be used with MAO inhibitors?
Ref: KD Tripathi 6/e p440 Most of Pethidine is metabolized by MAO-A and is inactivated. Small amount is conveed to nor-Pethidine, which has CNS stimulant propeies. Therefore if combined with MAO inhibitors, most of Pethidine will form nor-Pethidine and the risk of seizures will increase.
4
Morphine
Pentazocine
Buprenorphine
Pethidine
Pharmacology
Central Nervous system
93b8f356-4231-41b3-abd3-e65bd931be3c
single
A premature infant, when born, had low Apgar scores and was having difficulty breathing. The NICU physician injected a small amount of a lipid mixture into the child's lungs, which greatly reduced the respiratory distress the child was experiencing. In addition to proteins, a key component of the mixture was which one ...
The premature infant is experiencing respiratory distress syndrome, which is caused by a deficiency of lung surfactant. The lung cells do not begin to produce surfactant until near birth, and premature infants frequently are not producing sufficient surfactant to allow the lungs to expand and contract as needed. The su...
4
Sphingomyelin
A mixture of gangliosides
Triacylglycerol
Phosphatidylcholine
Biochemistry
Lipids
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multi
Apatient who is at risk of estrogen dependent carcinoma and hence estrogen is contraindicated. So in order to prevent vasomotor symptoms, which drug is given?
Clonidine REF: Novak's gynecology 13th edition page 455 In women for whom hormone replacement is contraindicated, multiple alternative treatments for hot flashes have been developed. Somewhat effective alternatives may be progestins such as medroxyprogesterone (10 to 30 mg daily orally) or megestrol acetate (20 to 40 m...
3
Tamoxifen
Conjugated estrogen
Clonidine
Yombinine
Gynaecology & Obstetrics
null
7022dc33-53a8-48de-8ba5-75bb9b6c44f6
single
In a patient with unerupted and impacted maxillary canine, the following radiographic techniques will be ideal for localization:
Typically, the occlusal radiograph is especially useful in the following cases:​ To locate precisely roots and supernumerary, unerupted, and impacted teeth (this technique is especially useful for impacted ​canines and third molars)​. To localize foreign bodies in the jaws and stones in the ducts of sublingual and sub...
2
IOPA and PNS view
Maxillary anterior occlusal view and IOPA
Bitewing and occlusal view
IOPA and occlusal view
Radiology
null
93c43c4c-29c8-470d-9981-0e3a9ebc445e
single
Which of the following does not exert an analgesic effect?
null
1
Cholinergic antagonists
Adrenergic antagonists
Morphine
Substance P antagonists
Pharmacology
null
807c4301-8817-413b-9df2-6d3fcda56f1a
single
Which one of the following statements best describes the mechanism of action of insulin on target cells?
Ans. (C) Insulin binds to a transmembrane receptor at the outer surface of the plasma membrane, which activates the tyrosine kinase that is the cytosolic domain of the receptor.(KDT 8th/e p58)Enzymatic Receptors have two sites, the drug binds on the extracellular site and the intracellular site has enzymatic activity (...
3
Insulin binds to cytoplasmic receptor molecule and is transferred as a hormone receptor complex to the nucleus where it acts to modulate gene expression.
Insulin binds to a receptor molecule on the outer surface of the plasma membrane and the hormone receptor complex activates adenylate cyclase through the Gs protein.
Insulin binds to a transmembrane receptor at the outer surface of the plasma membrane, which activates the tyrosine kinase that is the cytosolic domain of the receptor.
Insulin enters the cell and causes the release of calcium ions from intracellular stores.
Pharmacology
General Pharmacology
6009d4c6-2f58-4cc2-940e-9168dfd9b596
multi
Which of the following is not associated with the disorder characterized by the peripheral blood smear?
Sickle cell anemia is the most common familial hemolytic anemia. In parts of Africa, where malaria is endemic, the gene frequency approaches 30% as a result of a protective effect against Plasmodium falciparum malaria. Much more serious are vaso-occlusive crises, which are characteristically associated with pain and of...
3
Hand-foot syndrome
Acute chest syndrome
Predisposition to malaria
Predisposition to Salmonella osteomyelitis
Pathology
null
c477b0eb-9cd8-4305-91f2-cfd69611d2d9
single
The following condition is not associated with an Anti-phopholipid syndrome :
Answer is C (Thrombocytosis): A ntiphospholipid silirdrome is associated with thrombocopenia and not thrombocytosis. Common obstetric complications associated with antiphospholipid syndrome are: Recurrent fetal lossQ IUGRQ Pregnancy associated hypeensionQ Placental abruptionQ Recurrent thrombotic eventsQ Thrombocytopen...
3
Venous thrombosis
Recurrent foetal loss
Thrombocytosis
Neurological manifestations
Medicine
null
6b751507-2fff-49db-975f-a63662843c9f
single
Agranular cytoplasmic reticulum is involved in the synthesis of
Ans. is 'b' i.e. lipid [Ref: Guyton 11/e, p 20, 21; Chatterjee Shinde 6/e, p 6, 71There are two kinds of endoplasmic reticulum :Rough or granular ER or ergastoplasmThey are coated with ribosomesFunction of rough ERprotein synthesisSmooth or agranular ERThey do not have attached ribosomesFunctions of smooth ERlipid synt...
2
Protein
Lipid
Vitamin
Carbohydrate
Biochemistry
Miscellaneous (Structure & Function of Proteins)
95f71a4c-2e8c-4c57-b7d7-c35628fa2b19
single
All are seen in metachromatic leukedystrophy except?
Ans. is 'd' i.e., Exaggerated tendon reflexes
4
Mental retardation
Optic atrophy
Decerebrate posture
Exaggerated tendon reflexes
Pediatrics
null
254b2418-6416-4d69-8366-5175dc10d51b
multi