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Why a TB patient is recommend a regimen of 4 drugs on 1st visit -
Ans. is *a' i.e., To avoid emergence of persistors 6. Two phase chemotheraphyo There are two phase of treatment of tuberculosisIntensive phaseThis is short phase in the early course of treatment and lasts for 1-3 months.Three or more drugs are given to kill as many bacilli as possible, w hich prevents emergence of pers...
1
To avoid emergence of persistors
To avoid side effects
To cure early
null
Social & Preventive Medicine
Communicable Diseases
db97c2d4-0fed-4b4a-82b2-d1bcab9367d5
multi
The agent of choice for controlling heparin induced bleeding is
null
1
Protamine sulphate
Injectable vitamin K
Whole blood
Fresh frozen plasma
Medicine
null
dffcf095-396b-4068-a15f-b652e06c07d4
single
Gallow's traction is used for fracture -
Gallows traction is used for treatment of fracture shaft femur, in infants and children < 2 yrs of age.
1
Shaft femur
Neck femur
Shaft tibia
Tibial tuberosity
Orthopaedics
null
f16dd8e1-dcb4-45bf-84f1-76e40c3181e6
multi
Critical period of development of fixation reflex is
A. i.e. 2-4 months Unilateral cataract in children should be operated early in life because the critical period for development of fixation reflex is between 2" & 4th months of age.Q Age Visual Development At Bih * * * * Eye appear to move randomly & there is no central fixation Fovea is not fully developed & visual ac...
1
2-4 months of age
6-8 months of age
2 years
3 years
Ophthalmology
null
6b12637c-86f0-45d0-ae62-57248494864c
single
Over extension of complete denture for a prolonged period without adjustment may cause.
null
1
Epulis fissuratum
Pyogenic granuloma
Papillary hyperplasia
Giant cell reparative granuloma
Dental
null
1bf3873a-9655-4742-b1cf-b0bf676783ea
single
Which of the following is involved in peristalsis by causing relaxation ?
Ans. is 'c' i.e., VIP In peristlasis :- Acetylcholine & substance P - Causing smooth muscle contraction. VIP, NO & ATP - Producing relaxation ahead of stimulus.
3
Substance P
Acetylcholine
VIP
Norepinephrine
Physiology
null
89bbe76b-71fc-4051-a7e0-04a2c33d8ad4
single
Function of phospholipid in cell membrance is:
B i.e. Transduction of signals
2
Cell to cell variation
Transduction of Signals
Transmembrane preparation of protein
DNA replication
Physiology
null
6549bed4-6f07-41bf-b1ba-4854c7c20573
single
Which of the following is an atypical antidepressant?
Ans. is 'c' i.e., Venlafaxine Antidepressants A. Typical Tricyclic antidepressants NA + 5HT reuptake inhibitors :- Imipramine, Trimipramine, Amitriptyline, Clomipramine. Predominantly NA reuptake inhibitors :- Desipramine, Noriptyline, Amoxapine, Reboxetine. Selective serotonin reuptake inhibitors :- Fluoxetine, Paroxe...
3
Citalopram
Sealine
Venlafaxine
Reboxetin
Psychiatry
null
077ae14b-099b-42da-ad69-9af24d5e4762
single
Surfactant deficiency causes ?
Ans. is 'b' i.e., Respiratory distress syndromeInfant respiratory distress syndrome is due to deficiency of surfactant. Dipalmitoylphosphatidylcholine (Dipalmitoyllecithin) is the major constituent of surfactant.SurfactantSurfactant is a Soap-like substance secreted by the type-II pneumocytes of the alveolar epithelium...
2
Transient tachypnea of newborn
Respiratory distress syndrome
Neonatal jaundice
Hypeensive encephalopathy of newborn
Physiology
null
badd402a-995d-4d1b-9c26-74c12505fb79
single
Which of the following is seen in Churg-Strauss syndrome?
Churg-Strauss syndrome is a small vessel vasculitis. The acute presentation includes skin lesions, eosinophilia and asymmetric mononeuritis multiplex. There can be a prodromal period lasting many years in which the patient can have allergic rhinitis, nasal polyposis and asthma. Treatment is by high dose steroids and cy...
3
Sinusitis
Raynaud's phenomenon
Allergic rhinitis
Epistaxis
Medicine
All India exam
78b2011a-3d61-4594-a04d-1a1b5d831640
multi
Which of the following pontic designs require surgical procedure?
The ovate pontic is the pontic design that is most esthetically appealing. Its convex tissue surface resides in a soft tissue depression or hollow in the residual ridge, which makes it appear that a tooth is literally emerging from the gingiva.  Careful treatment planning is necessary for successful results. Socket-pre...
3
Modified ridge lap
Saddle
Ovate
Sanitary
Dental
null
6a6fc2f7-ba60-4205-bb1e-ac71de21e57b
single
Mild hoarseness with stridor is seen in:
(b) Bilateral abductor palsy(Ref. Current Diagnosis & Treatment Otolaryngology, Lalwani, 3rd ed., 478)Laryngomalacia and tracheal stenosis do not affect the VC hence voice remain normal in these though stridor is present.
2
Unilateral abductor palsy
Bilateral abductor palsy
Laryngomalacia
Tracheal stenosis
ENT
Larynx
e354f9c1-380f-4912-84aa-5a53f89a4a1c
single
Mechanism of action of bromocriptine is:
null
1
Agonism at D2 receptors
Antagonism at D2 receptors
Antagonism at D1 receptors
Antagonism at α receptors
Pharmacology
null
145af935-fb3f-411c-9965-f8d385f39902
single
Bruxism occurs in _______ phase of sleep
Bruxism can occur in any stage of sleep or at arousal from sleep. It is most common in stage N1 and N2 and least common during REM sleep Ref: guyton and hall textbook of medical physiology 12 edition page number: 721,722,723
3
ReM
NREM I
NREM II
NREM III
Physiology
Nervous system
9e4a1a85-feb4-4357-bc60-02e6051ddd7e
single
Which of the following is not a type of teukoplakia:
null
2
Ulcerative
Bullous
Speckled
Homogenous
Pathology
null
b4a6c3e9-30fe-4c5c-9d1f-87e0e43e5dcd
single
An infant presents with hypotonia and hyporeflexia. During his intrauterine period there was polyhydramnios and decreased fetal movements. Most probable diagnosis is -
Ans. is 'a' i.e., Spinal muscular atrophy o Out of the given options only spinal muscular atrophy is able to cause hypotonia and hyporeflexia during infancy. Rest of them either present late in childhood or do not give the symptoms. o Polyhydromnios and decreased fetal movements can occur in any neuromuscular disorder ...
1
Spinal muscular atrophy
Congenital myasthenia
Congenital myotonia
Muscular dystrophy
Pediatrics
null
2a25ac10-2bd9-40b7-aa7e-66829da11cec
single
Sterilization control used in membrane filters is
Sterilization control for membrane filters is Brevundimonas diminuta and sarratia marcescens.
4
B pumilis
B stereo thermophilus
C tetani
Brevundimonas diminuta
Microbiology
null
77abd1ce-c704-406e-8a3d-b1687782bac7
single
Halo sign and handkerchief test are positive in-
Ans. is 'a' i.e., CSF Rhinorrhoea Detection of CSF Leak in CSF Rhinorrhoea1) Biochemical testso Concentrations of Glucose are higher in CSF than in nasal discharge. Glucose value > 30-40 mg% protein value <100 mg % (max 200 mg %) support a diagnosis of CSF leako Presence of b2 transferrin is the most definitive test fo...
1
CSF Rhinorrhoea
Deviated nasal septum
Nasal Myiasis
Choanal atresia
ENT
Trauma of Nose and Face
a30f10bf-1c87-487f-ae7d-e719cb8fc2ab
single
A sea snake is -
null
3
Neurotoxic
Hemotoxic
Musculotoxic
All of the above
Forensic Medicine
null
b19f67cd-a8be-482f-b760-2109a43092c2
multi
Rotavirus vaccine- contraindication are all of the following EXCEPT?
ROTAVIRUS VACCINE- - Live oral vaccine - Given at 6,10 & 14 weeks (maximum age- 1 year) - Strain used- 116E strain of Indian origin - Contraindications: SCID Previous history of Intussusception / severe allergic reaction to a previous dose of the vaccine.
4
SCID
Intussusception
Severe allergic reaction
Child on top feeds
Pediatrics
Types of vaccines
b91a8673-4f24-4d83-a9b2-3dea567855f0
multi
Which of the following prostaglandin analogues used in Glaucoma
(Latenoprost): Ref: 88-KDT, 394-Khurana 3rd (147-KDT 6th)* Prostagland analogues used in Peptic ulcer are - Misoprostol Enprostil, Rioprostil (588-KDT)* LATANOPROST (0.0005%) It is synthetic drug which is an ester analogue of prostagland in F2a* It acts by increasing uveoscleral outflow and by causing reduction in epis...
2
Misoprostol
Latanoprost
Enprostil
Rioprostil
Pharmacology
Prostaglandins
109d3ec5-7c75-4181-884f-65ff0741c1b0
single
Which can cause loose body in the joint -
Ans. is 'c' i.e., OA o Causes of loose bodies includei) Osteoarthritisiii) Osteochondral fracture (injury) v) Synovial chondromatosisii) Osteochondritis dessicansiv) Charcot's disease o Among these, osteochondral fracture causes single loose bodies, while all other can cause multiple loose bodies, maximum by synovial c...
3
RA
Ankylosing spondylitis
OA
SLE
Orthopaedics
Arthritis
4409c8da-0b8a-4df2-8b4f-a5cb0f24cd6f
single
Which of the following is an example of disability limitation?
Resting affected limbs in neutral position Repeat from May 06 & 07 Disability limitation is the mode of intervention used if the patient presents in late pathogenic phase. The objective is to prevent the transition of the disease proecess from impairment to handicap. The sequence of events leading to disability and han...
3
Reducing occurrence of polio by immunization
Arranging for schooling of child suffering from PRPP
Resting affected limbs in neutral position
Providing calipers for walking
Social & Preventive Medicine
null
5ecd4ade-4b2d-4563-9161-08d1c41e8029
single
MRI is the investigation of choice in all of the following complications of CSOM except:
MRI gives little information in bone disease and is not useful in coalescent mastoiditis' in which CT scan would be the investigation of choice. It shows bone destruction and coalescence of mastoid air cells. In Bezold abscess, size, extent and location of abscess in soft tissues can be appreciated.Similarly, extradura...
3
Extradural abscess
Bezold abscess
Coalescent mastoiditis
Cerebral abscess
ENT
Ear
b1c1b9bc-4ac2-4775-959e-c2367ca89f96
multi
When launching a study, many respondents are invited, some of whom fail to come, this is called
.
1
Response bias
Volunteer bias
Selection bias
Berkesonian bias
Social & Preventive Medicine
Epidemiology
edf72077-5bc7-4157-aa8a-ff41f348bad1
multi
A patient with salicylic acid poisoning has the following arterial blood gas analysis report: pH = 7.12; PCO2 = 18 mmHg; HCO3 = 12 mmol/L. The resulting acid-base abnormality can be best labeled as:
Ans. is 'a' i.e. Metabolic acidosis with respiratory alkalosisRef. Harrison 17th/e p 288 & 16th/e p 2591, 266 (15th/e page 284, 286,187)Also see June 2000 Q. No. 94.In patients with salicylate poisoning, initially the acidic metabolites of salicylic acid accumulate and cause metabolic acidosis.This causes the following...
1
Metabolic acidosis with respiratory alkalosis
Metabolic acidosis with respiratory acidosis
Respiratory acidosis with metabolic alkalosis
Metabolic acidosis
Medicine
Fluid & Electrolyte
9602a861-4056-4800-9bd2-ea8f1e285434
single
Which of the following drugs is best for reducing pro teinuria in a diabetic patient?
ACE inhibitors like lisinopril, perindopril, ramipril and ARBs like losaan, telmisaan could decrease the incidence of diabetic nephropathy by decreasing protein levels in the urine especially albumin They r DOC for diabetes with HTN. Ref: KD Tripathi 8th ed.
2
Metoprolol
Perindopril
chlohiazide
Clonidine
Pharmacology
Cardiovascular system
da1479d3-dc75-4a01-b255-b11fe5d9fbf1
single
Drug of choice for precocious pubey:
Treatment of precocious pubey: Rx the underlying cause Long acting GnRH analogues (Leuprolide)
4
Cyproterone acetate
Danazol
Medroxyprogesterone
GnRH agonists
Pediatrics
Disorders of Pubey
b2e65332-8691-44d0-819c-91eb2c26a32f
single
Awareness of having a disease is
Ans. a (Insight). (Ref. Psychiatry by Niraj Ahuja, 5th ed., 14, 41, 57, 72, 85, 95, 171)Term DefinitionPerseverationis persistent repetition of words beyond their relevance.Verbigerationis senseless repetition of same words or phrases.Delusionsare false unshakable belief in something that is not true.Insightis awarenes...
1
Insight
Perseveration
Delusion
Incoherence
Psychiatry
Miscellaneous
172853cc-506a-4da4-bef0-9295fa1fa79d
single
Carbohydrate-related to blood grouping?
The major blood groups of this system are A, B, AB, and O.O type RBCs lack A or B antigens. These antigens are carbohydrates attached to a precursor backbone, may be found on the cellular membrane either as glycosphingolipids or glycoproteins, and are secreted into plasma and body fluids as glycoproteins. H substance i...
4
Arabinose
Xylulose
Xylose
Fucose
Surgery
General surgery
ec8ce4a8-a881-4e63-a1a9-24b3c710d034
single
All of the following factors decrease the minimum alveolar concentration (MAC) of an inhalational anaesthetic agent except
MINIMUM ALVEOLAR CONCENTRATION: The MAC of an inhaled anesthetic is the alveolar concentration that prevents movement in 50% of patients in response to a standardized stimulus (eg, surgical incision). MAC is a useful measure because it mirrors brain paial pressure, allows comparisons of potency between agents, and prov...
3
Hypothermia
Hyponatremia
Hypocalcemia
Anemia
Anaesthesia
Fundamental concepts
d4a2c9b1-018d-4a49-bd7a-f173c5ad9dae
multi
A 27-year-old patient with a chief complaint of mild veigo of 3-months duration is seen by a neurologist. Examination reveals a positional (horizontal and veical) nystagmus that is bidirectional. The patient repos the absence of tinnitus. Which of the following is the most likely etiology of veigo?
Pathologic veigo is generally classified as peripheral (labyrinthine) or central (brainstem or cerebellum).The clinical presentation, in this case, is most consistent with central veigo. Positional (especially horizontal) nystagmus (to-and-fro oscillation of the eyes) is common in the veigo of central origin, but absen...
3
Labyrinthitis
Meniere's syndrome
Lesion of the flocculonodular lobe of the cerebellum
Lesion of the spinocerebellum
Microbiology
All India exam
29dc1dd9-b79a-408a-a2b8-89544613b6ce
single
Cephalosporin that does not require dose reduction in patient with any degree of renal impairment is:
CEPHALOSPORINS These are a group of semisynthetic antibiotics derived from &;cephalosporin-C&; obtained from a fungus Cephalosporium. They are chemically related to penicillins; the nucleus consists of a P-lactam ring fused to a dihydrothiazine ring, (7-aminocephalosporanic acid). By addition of different side chains a...
2
Cefuroxime
Cefoperazone
Ceftazidime
Cefotaxime
Pharmacology
Chemotherapy
bfdd8469-050c-4a06-b4bd-e7047e590ff7
single
Germ cell tumor(s) of paediatric includes all except?
Ans. is 'b' i.e., Leydig cell tumor Germ cell tumors o Germ cell tumors, as the name suggests, arise from Primordial germ cells (Precursor germ cells or gametocytes), o Germ cells develops early in life. In growing fetus, germ cells migrate from their point of origin to the gondal area. o Germ cells that still have to ...
2
Pure yolk sac tumor
Leydig cell tumor
Choriocarcinoma
Embryonal cell carcinoma
Pediatrics
null
a302a433-875d-446f-855b-2f8dfc39d874
multi
Regarding the action of Anti Diuretic Hormone (ADH) all are true, except:
ADH/Vasopressin is stored in the posterior hypothalamus and is released into the blood stream when the effective osmotic pressure of plasma is increased above 285mOsm/kg. Its secretion is regulated by osmoreceptors located in the anterior hypothalamus. Vasopressin secretion is increased in: Increased effective osmotic ...
2
Post operative secretion is more
ADH secretion occurs when plasma osmolality is low
Acts on DCT
Neurosecretion
Physiology
null
598e0602-1fc3-4364-91ff-d6f5a4be0754
multi
The medium of choice culturing yeast form of dimorphic fungi is:
Ans. is 'c' i.e., SDA with antibioticsSDA with antibiotics (Chloramphenicol) is always preferred over plain SDA to avoid bacterial contamination and make it more selective.
3
BHI
SDA
SDA with antibiotics
Any medium incubated at 35-37deg C
Microbiology
Mycology
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single
True statements regarding DMPA includes all the following except :
Risk of endometrial cancer is substantially reduced by past use of DMPA Noncontraceptive benefits of DMPA:Anemia, PID, Ectopic pregnancy, and Endometrial cancer are repoedDMPA benefits women with sickle cell diseaseRef: Novak and Bereks Gynecology; 15th Edition; Chapter 10
2
3% failure rate
Protects against ovarian cancer
Can be given in women with seizures
Useful in treatment of menorrhagia
Gynaecology & Obstetrics
Contraception
6dcb3757-04e2-4e4d-82ad-a4a093ddd3ab
multi
Which of the following does not come in contact with anterolateral surface of left kidney?
A small medial area of the superior pole is related to the left suprarenal gland. Approximately the upper two-thirds of the lateral half of the anterior surface is related to the spleen. A central quadrilateral area lies in contact with the pancreas and the splenic vessels. Above this a small variable triangular region...
2
Spleen
Liver
Stomach
Pancreas
Anatomy
null
063bcfd8-17ce-4ff2-9640-d5f11871b53a
single
Which of the following is TRUE regarding classical spontaneous bacterial peritonitis ?
Spontaneous bacterial peritonitis (SBP) is one of the potentially lethal complications of cirrhosis and is defined as infected ascites in the absence of any recognizable secondary cause of infection. .UGI bleeding and abdominal pain were the most common presenting symptoms of SBP SBP is an acute ascites infection an as...
1
Ascitic fluid neutrophil count is > 250/mm'
Bowel perforation should be present
Multiple organisms are isolated from ascitic fluid
Board-like rigidity is present in abodmen
Medicine
G.I.T
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multi
Non specific esterase is positive in all the categories of AML except
Non specific esterase on cytochemistry is strongly positive in M5(acute monocytic leukemia- Schilling type) and M4(acute myelomonocytic leukemia -Naegeli type) which have monocytic component.It is also positive in M3(acute promyelocytic leukemia).But non specific esterase is negative in M6(acute erythroleukemia-Di Gugl...
4
M3
M4
M5
M6
Pediatrics
Childhood tumors
52e42883-d6cb-4ad2-a34c-20900948ffcb
multi
A young patient presents with enlargement of costocondral junction and with the white line of fraenkel at the metaphysis. The diagnosis is-
*Enlargement of costochondral junction and white line of Frankel are seen both in scurvy and rickets. *However, best answer here is scurvy as white line frankel is seen in healing rickets, not in active rickets. And rickets refers to active disease. ref : maheswari 9th ed
1
Scurvy
Rickets
Hyperparathyroidism
Osteomalacia
Anatomy
Metabolic and endocrine disorders
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single
A 54-year-old woman presents with prominent scattered erythematous papules on the right side of her forehead. She had "burning" pain and hypersensitivity in that area for the past 2 days. Her pain is localized to the right supraorbital area and the right aspect of the dorsum of her nose. She denies headaches, mental st...
Woman is suffering from herpes zoster, or "shingles" - a late complication of prior infection with varicella zoster virus. The virus remains latent in the ganglia of sensory nerves after the primary infection. The characteristic shingles rash is always confined to a dermatome and does not cross the midline. Specificall...
2
Early Cellulitis
Varicella zoster
Giant cell aeritis with ulceration
Erysepalas
Dental
Viral infections
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single
Atropine is used in organophosphate poisoning because of its
Refer kDT 6/e p 106 atropine acts as antagonist in muscarinic receptors. It has no activity on nicotinic receptors and do not interfere with the release of acetylcholine
4
Reactivate acetylcholinesterase
Compete with acetylcholine release
Binds with both nicotinic and muscarinic acetylcholine receptors
It is competitive antagonist of acetylcholine
Anatomy
General anatomy
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multi
The major functional difference between DNA and RNA is
null
2
RNA contains ribose
DNA carries the information in all living organisms
DNA is localized in nucleus
RNA does not contain thymine
Physiology
null
72d08e62-576f-4568-af0d-b08d3dfc59a5
multi
Most "Radiosensitive" Tissue is:
Bone-marrow
2
Gonads
Bone-marrow
RBC
GIT epithelium
Radiology
null
06ac2735-96b1-4ef2-b0c2-cd7b39749e8f
single
Which of the following drugs is associated with the untoward side effect of renal tubular damage?
Cisplatin is a highly emetic and nephrotoxic agent. Streptozocin causes the destruction of β-cells of the pancreas and may result in hyperglycemia. Methysergide can cause retroperitoneal fibrosis on long-term use. Cyclophosphamide can result in hemorrhagic cystitis.
1
Cisplatin
Streptozocin
Methysergide
Cyclophosphamide
Pharmacology
null
f4d29428-7d26-4ac0-8d6e-106e91127de1
single
If urine sample darkens on standing, the most likely condition is :
Alkaptonuria a condition d/t defective homogentisate 1, 2- dioxygenase (1/t defective tyrosine degradation) usually presents after age of 40 with characteristic triad of Homogentisic aciduria (which blacken/darkens on exposure to air /standing and is strongly Benedict's positive), Ochronosis (i.e black pigmentation of ...
2
Phenylketonuria
Alkaptonuria
Maple syrup disease
Tyrosinemia
Biochemistry
null
5d3dcce3-bc5c-4014-a53e-7d5c5faaf805
single
The different semen in case of gang rape is identified by:-
Single photon fluorimetry has been used to differentiate between different semen in a gang rape case TESTS FOR SEMINAL STAINS Creatine phosphokinase test Acid phosphatase testQ Florence testQ (Choline iodide crystals) Barberio's test (crystals of spermin picrate)
4
Acid phosphatase test
Christmas tree stain
PSA
Single photon flourimetry
Forensic Medicine
Trace evidences
d588dcab-db70-4a04-bd1c-20228f28da86
single
Submucosal fibroid is detected by :
Ans. is a, b and c i.e. Hysteroscopy; Hysterosalpingography; and USG (Transabdominal) USG * Ultrasound is the main diagnostic tool in case of fibroid.deg It checks the numberdeg, locationdeg and sizedeg of fibroids and helps to reduce overlooking small fibroids during surgery (which might lead to persistence or recurre...
4
Hysteroscopy
Hysterosalpingography
USG (Transabdominal)
All
Gynaecology & Obstetrics
null
794f3bf4-844d-438f-930b-fcfaa1b35201
multi
The tumor causing polycythemia due to erythropoietin production is -
<p>The tumors causing inappropriate rise in erythropoietin are renal cell caarcinoma,hepatocellular carcinoma ,cerebellar hemangioblastoma.</p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 359.</p>
1
Cerebellar hemangioma
Medulloblastoma
Ependymoma
Ougodendroglioma
Medicine
Haematology
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single
A female with IUCD develops pelvic inflammatory disease. which of the following should be done:
Ans. is 'a' i.e., Keep the IUCD, give antibiotic, follow up for antibiotic response & then take decision regarding IUCDremoval If an IUD user receives a diagnosis of PID, the IUD does not need to be removed. However, the woman should receive treatment according to these recommendations and should have close clinical fo...
1
Keep the IUCD, give antibiotic, follow up for antibiotic response & then take decision regarding IUCD removal
Sta antibiotic & remove IUCD
Remove IUCD & sta antibiotic
Wait for next menstrual cycle for any intervention
Gynaecology & Obstetrics
null
0960aa1f-42fc-48db-bf36-94d098a4807e
single
Which of the following culture medium is made by adding Agar:
Ans. (a) Solid mediumRef: Microbiology by Ananthanarayan and Paniker 8th ed. / 39-40GROWING BACTERIAL CULTURES IN LIQUIDNUTRIENT BROTH* Nutrient broth is a liquid bacterial growth medium made of powdered beef extract and short chains of amino acids that have been dissolved in water.* Liquid medium is convenient to use ...
1
Solid medium
Liquid medium
Selective medium
Transport medium
Microbiology
Culture media and method
ed9da13f-c9c0-401d-87db-696fc9e09ff7
single
Amphiphatic helices are
Many α helices have predominantly hydrophobic R-groups projecting from one side of the axis of the helix and predominantly hydrophilic R-groups projecting from the other side. These amphipathic helices are well adapted to the formation of interfaces between polar and nonpolar regions such as the hydrophobic interior of...
1
α helices having predominantly hydrophobic R-groups projecting from one side and predominantly hydrophilic R-groups projecting from the other side of the axis of the helix
Clusters of twisted strands of β sheet
Short segments of amino acids that join two units of the secondary structure
Supersecondary structures
Biochemistry
null
1d17bad7-792e-4122-a4f1-ff9f32fa1307
single
In Duke's classification of cancer rectum, B2 denotes -
null
3
Growth extends to perirectal fat
Regional nodes involved
Limited to thickness of bowel wall
Hepatic metastasis
Pathology
null
3ded4e6d-f5b6-4ff1-a91d-7d00e8c6bb7f
multi
Maximum density of goblet cells is seen in
Goblet cells form the mucus layer of the tear film They are maximum nasally and least superiorly REF:Refer Khurana 6th edition page number 59
4
Superior conjunctiva
Inferior conjunctiva
Temporal conjunctiva
Nasal conjunctiva
Ophthalmology
Conjunctiva
6576cf14-bd25-4d13-bf8c-cf1e634d918d
single
Which is the most common cytogenetic abnormality in myelodysplastic syndrome (MDS)?
Monosomy 7 is most common cytogenetic abnormality in children whereas 5q - is seen frequently in adults and is very rare in children. Although 5q may be commoner than monosomy 7 in some settings, overall monosomy 7 appears more common. Myelodysplastic syndromes are a group of stem cell disorders with altered hematopoes...
4
Trisomy 8
20q-
5q-
Monosmy 7
Pathology
null
f4cca320-2458-488e-b44c-868116f03d10
single
Appendicitis-like syndrome is caused by
Yersinia enterocolitica: Type 1- Enterocolitis and gastroenteritis; Type 2- mesenteric adenitis and inflammatory terminal ileitis that may mimic appendicitisYersinia pseudotuberculosis: also mimics appendicitisRef: Ananthanarayan 9th edition, p324
2
Y. pestis
Y. pseudotuberculosis
Pasturella septica
Brucella abois
Microbiology
Bacteriology
d7eae1cb-dfc2-4e82-b300-166ee4e8709e
single
Which of the following parameters adds predictive information regarding cardiovascular risk stratification and the measurement of serum cholesterol?
Recent studies have demonstrated that markers of inflammation correlate with coronary risk and that inflammation plays a role in atheromatous plaque instability. Elevations of C-reactive protein, (CRP) identify patients at increased risk of myocardial infarction (MI) and poor outcome of acute coronary syndromes. Measur...
2
Anti-chlamydia pneumoniae antibodies
C-reactive protein
Homocysteine
Plasminogen activator inhibitor 1
Medicine
null
62d24ba7-2223-4392-a811-8065c7838246
single
Side effects of oxygen therapy are all except:
B i.e., Increased pulmonary compliance Hyperoxia (oxygen toxicity) may lead to hypoventilation, hypercapnia (but not necessarily hypoxia), absorption atelectasis, decreaed vital capacity, deterioration of pulmonary compliance & blood gasesQ, interstitial edema, pulmonary fibrosis, tonic clonic seizure & retinopathy of ...
2
Absorption atelactasis
Increased pulmonary compliance
Decreased vital capacity
Endothelial damage
Anaesthesia
null
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multi
Irresistible urge to do a thing repeatedly is seen in
An obsession is defined as an idea, impulse or image which intrudes into the conscious awareness repeatedly, patient tries to resist against it but is unable to . an obsession is usually associated with compulsion and a compulsion is defined as a form of behaviour which usually follows obsessions,the behaviour is not r...
1
Obsessive - compulsive disorder
Schizophrenia
Schizoaffective disorder
Depression
Psychiatry
Anxiety disorders stress disorders and grief
5e4d2fdd-8412-49dc-804a-7207fded32c8
single
Duret haemorrhage is/are seen in:
D i.e. Brain Whiplash injury results from acute hyperextension of cervical spineQ in the region of C4 - C6 veebrae. Coup & Count-re coup lesions are most commonly seen in brainQ. Lucid interval is seen in insanity & epidural haemorrhageQ Fracture - ala - signature / signature fracture is also known as depressed fractur...
4
Conjunctiva
Middle ear
Endocardium of hea
Brain
Forensic Medicine
null
472c9c79-3263-4324-bbb8-8254948cfd0c
single
CD 19 positive, CD22 positive, CD103 positive monoclonal B-cells with bright kappa positivity were found to comprise 60% of the peripheral blood lymphoid cells on flow cytometric analysis in a 55 year old man with massive splenomegaly and a total leucocyte count of 3.3 x 109/L. Which one of the following is the most li...
Answer is D (Hairy cell leukemia) Presence of massive splenomegaly, and granulocytopenia, alongwith characteristic immunophenotypic features (specially CD103) suggests the diagnosis of Hairy cell leukemia. CD103 is exclusively positive in Hairy cell leukemia and thus leaves no doubt as regards the correct diagnosis.
4
Splenic lymphoma with villous lymphocytes
Mantle cell lymphoma
B-cell prolymphocytic leukemia
Hairy cell leukemia
Medicine
null
39130a40-67a1-4dd9-a494-cc1dbfb14eef
single
Most specific marker for myeloid series is
The markers for myeloid series are CD13, CD33, CD 11b, CD15, CD117 and cMPO. c MPO is the most lineage specific marker amongst these. Regarding other options, CD 34 - Myeloid and lymphoid blasts, stem cells, CD 45 - Leukocyte common antigen (nonerythroid hematopoietic cells), CD 99 - Ewing's sarcoma/primitive neuroecto...
4
CD 34
CD 45
CD 99
CD 117
Pathology
Diagnostic procedures
83965e8c-d334-49ad-a40a-ff226ba11e09
single
Which surgical procedure has the highest incidence of ureteric injury?
The Weheim type of radical hysterectomy for cancer of the cervix is notorious for ureteric injury for which over-dissection of the ureter or accidental injury is most often responsible. Ref: Shaw's Gynaecology, 13th Edition, Pages 180-81; Dutta Gynecology, 4th Edition, Pages 391-92; Management of Common Problems in Obs...
3
Vaginal hysterectomy
Abdominal hysterectomy
Weheim's hysterectomy
Anterior colporraphy
Gynaecology & Obstetrics
null
07822661-2aca-4f91-a6b9-3406e2d6b956
single
An 18 year old student complains of lack of interest in studies for last 6 months. He has frequent quarrels with his parents and has frequent headaches. The most appropriate clinical approach would be:
B i.e. Rule out depressionLet us consider the options one by one. This can be a normal behaviour but use definitely need to rule out of few disorders before reaching this conclusion. Recent studies have suggested a possible correlation b/w migraine and behavioural problems. There is nothing in the question to point out...
2
Leave him as normal adolescent problem
Rule out depression.
Rule out migraine.
Rule out an oppositional defiant disorder.
Psychiatry
null
328dc4a1-e76f-4e5a-b0a2-22cd463dcb00
single
Which of the following is FALSE regarding Kishori Shakti Yojana?
It is a scheme for adolescent girls and is being implemented using the ICDS infrastructure. It targets girls between 11 - 18 years of age. It addresses their needs of self development, nutrition and health state's, literacy and numerical skills, vocational skills etc. Ref: Park, Edition 21, Page - 545.
1
Targets pregnant woman
Targets girls in the age group 11 - 18 year
It addresses the needs of literacy and numerical skills
It addresses the nutritional needs
Social & Preventive Medicine
null
403f2990-e071-45f6-a054-0695a148a5e5
multi
All of the following statements about synovial fluid are true. Except-
synovial fluid is plasma transudate from synovial capillaries, modified by secretory activities of type-B synovial lining cells.
2
Follows Non - Newtonian fluid kinetics
Secreted primarily by type A synovial cells
Contains hyaluronic acid
Viscosity is variable
Orthopaedics
null
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multi
A 25 year old male was hospitalized with liver cyst due to Echinococcus granulosus. He refused to undergo surgery for removal of cyst. Therefore, albendazole was used at high dose for 3 months. This patient should be monitored for the toxicity to :
null
3
Gonads
Kidney
Liver
Peripheral nerves
Pharmacology
null
79f45476-3669-45d1-8f9f-226e20d829e4
single
ln which of the following transmission, meiosis occurs :
Primary to secondary spermatocyte
1
Primary to secondary spermatocyte
Secondary spermatocyte to globular spermatid
Germ cells to spermatogonium
Spermatogonium to primary spermatocyte
Anatomy
null
efd08e7f-c8a3-4ec4-92e1-8fa9b0479bf6
single
Copper-T is preferably inseed postnatal, after:
Timings of IUD inseion During menstruation or within 10 days of begining of menstrual period: Best time for IUD inseion Cervical canal diameter greatest, lesser expulsive, least risk of pregnancy. Immediate post-paum inseion: During 1st week after delivery before woman leaves hospital. High chance of perforation High c...
4
2 weeks
4 weeks
5 weeks
8 weeks
Social & Preventive Medicine
Demography and family planning
8e4f61b0-cd26-4647-913d-136f0d3e6e16
single
Consider the following statements regarding thyroid hormones-
Thyroid Hormones physiology The thyroid secretes predominantly thyroxine (T4) and only a small amount of triiodothyronine (T3); approximately 85% of T3 in blood is produced from T4 by a family of monodeiodinase enzymes that are active in many tissues, including liver, muscle, hea and kidney. Selenium is an integral com...
1
Majority of the circulating T3 remains in bound form
Only 50% of the circulating T3 is secreted by Thyroid
TSH estimation is not a sensitive test for diagnosis of primary hypothyroidism
Fatel pituitary-thyroid axis is dependent to a large extent on maternal pituitary-thyroid axis
Medicine
Endocrinology
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multi
who gave the concept of la belle indiffernce
CONTRIBUTIONS OF FREUD o Father of psychoanalysis He founded a type of psychotherapy called psychoanalysis. It is nothing but analyzing the psych(MIND) o Interpretation of dreams According to Freud dreams are royal road to unconscious In dreams several conflicts that are present in the unconscious comes to the consciou...
3
seligman
lorenz
freud
bleuler
Anatomy
Treatment in psychiatry
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single
Vitamin A is stored in:-
HSCs (Hepatic Stellate Cells) are: Pericytes which exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule. Also called Vitamin A-storing cells, Lipocytes, Interstitial cells, Fat-storing cells or Ito cells, Perisinusoidal cells Store 50-80% of vitamin A in the whole bo...
3
Kupfer cells
Hepatocytes
Ito cells
Endothelial cells of liver
Biochemistry
NEET 2019
b5988495-d56c-42ab-a01d-3a769711b7cf
single
The best bone graft which can be utilized for reconstruction is:
null
3
Costo chondral graft
Calvarial graft
lilac crest graft
Metatarsal bone graft
Dental
null
80004ad9-1a07-4bf4-ab19-852425e0b1f6
single
The best parameter for assessment of chronic malnutrition is -
parks textbook of preventive and social medicine 23rd edition * height is a stable measurement of growth as opposed to body weight .whereas the weight reflects only the present health status of the child,height indicate the events in the past also. *low height for age also knownn as nutritional stunting or drawfting.it...
3
Weight of age
Weight for height
Height for age
Any of the above
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
54648451-e155-4f8f-87ba-1584183aeb4e
multi
True about the basic structure of atherosclerosis plaque is ?
Ans. is 'c' i.e., Convex pa formed by fibrous cap
3
Concave pa formed by fibrous cap
Convex pa formed by tunica media of the vessel
Convex pa formed by fibrous cap
Necrotic core contains collagen, elastin and proteoglycans
Pathology
null
1d772eff-6181-49b2-baee-8ed7c6574d1e
multi
Right border of heart is formed by all except -
Ans. is 'b' i.e., Right ventricle o Dont get confused with above question. Most probably this question has been framed by a radiologist. Read following factsi) Right border of heart is formed by (anatomically) - Right atrium.ii) Right border of heart is formed by (on X-ray PA view) - Right atrium (majority), SVC, I VC....
2
Right atrium
Rightventricle
SVC
IVC
Anatomy
Pericardium & Heart
31af59cc-67d0-4056-8338-8f028f26eb5d
multi
Rao and Singh's index is?
RAO & SINGH'S INDEX: - It is calculated as Weight (in kg) x 100/height2 (in cm) - Normal value: 0.14 - In children with malnutrition: 0.12 - 0.14
2
Age-dependent index
Age-independent index
Age and sex-dependent index
Independent of wt and ht
Pediatrics
Growth
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single
Adult scabies is characterized by?
A i.e. Involve palm & soles
1
Involve palm & soles
Involve face
Involve anterior abdomen
All
Skin
null
f0ba3c8f-0f3b-47d4-a3c4-15f6a495f26f
multi
All are elevators of the larynx except -
Elevators : Primary elevators act directly as they are attached to the thyroid cartilage and include stylopharyngeus, salpingopharyngeus, palatopharyngeus and thyrohyoid. Secondary elevators act indirectly as they are attached to the hyoid bone and include mylohyoid (main), digastric, stylohyoid, geniohyoid. Depressors...
4
Thyrohyoid
Digastric
Stylohyoid
Sternohyoid
ENT
null
e69da445-8863-4ac0-9d9e-a27d5b9fd260
multi
Leukemia associated with Disseminated Intravascular Coagulation is:
Major Disorders Associated With Disseminated Intravascular Coagulation (DIC) Obstetric Complications Abruptio placentae Retained dead fetus Septic Abortion Amniotic fluid embolism Toxemia Infections Sepsis (gram-negative and gram-positive) Meningococcemia Rocky Mountain spotted fever Histoplasmosis Aspergillosis  ...
2
Acute lymphocytic leukemia
Acute promyelocytic leukemia
Chronic myeloid leukemia
Chronic lymphoid leukemia
Pathology
null
538ef57b-9b58-4be3-b70e-49f492885264
single
The effect of morphine which has least tolerance is?
ANSWER: (C) ConstipationREF: KDT 6th edition page 457Tolerance is exhibited to all actions except meiosis and constipation
3
Analgesia
Respiratory depression
Constipation
Bradycardia
Pharmacology
Opioids
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single
Stability of denture can be increased by
V-Y plasty procedure or Z plasty procedure is used for frenectomy procedure to increase the stability of denture.
3
V-Y plasty procedure
Z plasty procedure
Both
null
Surgery
null
7f3d49bb-f723-436b-9c34-de28dfb5e911
multi
'Meralgia paresthetica' is due to the compression of which off the follwoing nerves?
Meralgia Paraesthetica results from compression neuropathy of the lateral cutaneous nerve of thigh. It is also called Bernhardt-Roth syndrome. This nerve can be compressed as it runs through the inguinal ligament, just medial to the Anterior superior Iliac spine. Pain, numbness, tingling and paresthesia localised to an...
2
Medial cutaneous nerve of thigh
Lateral cutaneous nerve of thigh
Sural nerve
Femoral nerve
Surgery
null
ae711017-66be-45f1-87f0-293e670c88b1
single
Example of secondary active transport-
Ans. is 'd' i.e., Na+-amino acid transport Transport mechanismExamplesSimple diffusionMovement of fats, oxygen, CO2 through lipid portion of membraneFacilitated diffusionMovement of glucose and some amino-acidsOsmosisMovement of water into and out of the cellPrimary active transportIons K+, Na+, Ca++, H+Secondary activ...
4
K+ transport
Water Transport
Transport of oxygen
Na+-amino acid transport
Physiology
Transport Across Cell Membrane
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single
Microscopic examination of a specimen shows 'Schiller-Duval bodies'. This most probably will have:
Yolk sac tumor only occurs as a pure tumor in young males (at about 3 years of age). In adults, yolk sac tumors are pa of mixed germ cell tumors. One characteristic feature of yolk sac tumor is Schiller-Duval bodies, which resemble endodermal sinuses. Schiller-Duval bodies have a capillary at the core and are surrounde...
3
Seminoma
Choriocarcinoma
Yolk sac tumor
Embryonal carcinoma
Gynaecology & Obstetrics
null
4a7e2645-fa04-4e3a-9527-db58296dee3d
single
Pre-anaesthetic medication is given to ?
Ans. is 'd' i.e., All of the above Preanaesthetic medication Premedication (Preanaesthetic medication) refers to the use of drugs before anaesthesia to make it more pleasant and safe. The aims are : Relief of anxiety and apprehension preoperatively and to facilitate smooth induction. Amnesia for preoperative and postop...
4
Reduce anxiety and fear
Reduction of secretion of saliva
To prevent undesirable reflexes
All of the above
Anaesthesia
null
a84f80bb-febe-49d3-8290-4ecda820da87
multi
Rate limiting step in facilitated diffusion?
Ans. is'b'i.e., Conformational change in transpoer(Ref: Essentials of membrane Biophysics p. 25I).The relative slowness of the rate constant for conformational change reorienting the Solute-unoccupied transpoer (Step-4) makes it the rate-limiting step in the process of facilitated diffusion.
2
Availability of contranspo
Conformational change in transpoer
Synthesis of carrier protein
Polarization of solute
Physiology
null
65c4d2d3-b886-48c3-b65f-bd9098894659
multi
Fixed performance device is –
Ventimask (venturi mask) is a fixed performance (high flow) oxygen delivery device. Nasal cannula, non-rebreathing mask (Hudson mask) and simple mask are variable performance (low flow) devices.
1
Ventury mask
Nasal cannula
Simple mask
Non rebreathing mask
Anaesthesia
null
e11e0a84-54e0-4678-9060-26a198f5bce8
single
Hemivertebra is a defect of:
Ans. A. Bodya. Vertebral bodies mainly develop from ventral sclerotome (VS) and thus hemivertebra is a defect of VS.b. Hemivertebra can lead to defects in the vertebral column - scoliosis.c. Posterior vertebral arches (PVA) contribute mainly to the lamina & spines. PVA are contributed by the dorsal sclerotome.
1
Body
Transverse process
Spine
Posterior vertebral arches
Anatomy
Thorax
8a0b0d9a-79c0-4f79-9880-e590026bad08
single
Not a metabolic product of urea cycle-
Biosynthesis of urea occurs in five steps. 1) Carbamoyl phosphate synthase-I (CPS-I), a mitochondrial enzyme, catalyzes the formation of carbamoyl phosphate by condensation of CO2 and ammonia. Two molecules of ATP are required for the reaction. CPS-I is the rate-limiting enzyme of the urea cycle. It is an allosteric e...
3
Citrulline
Ornithine
Alanine
Arginine
Biochemistry
null
d518d93d-6d27-499d-bdd9-68814eeef581
single
A patient was operated for forearm fracture under general anesthesia under tourniquet. Following surgery, he was unable to move his fingers and there was sensory loss over the whole hand. Most common type of injury is:
Ans. A. NeuropraxiaTourniquet paralysis is usually Neuropraxia. Application of tourniquet may press on all the nerves passing beneath it, resulting in mostly neuropraxia.
1
Neuropraxia
Axonotmesis
Neurotmesis
None of the above
Orthopaedics
Peripheral Nerve Injuries
2b7b3a5f-af45-4cb8-a84f-72959bb9bdf1
multi
Most common source of error in a false positive finding of dental caries is:
Although this can be caused by a variation in the morphology of the tooth, the most common source of error is the misinterpretation of cervical burnout as dental caries. Cervical burnout produces an artifact that mimics a carious lesion near the cementoenamel junction (CEJ) area of the tooth. As the X-ray beam meets th...
1
Cervical burnout
Fluorosis
Dental pigmentation
All of the above
Radiology
null
feccd93c-1c40-4e26-84af-a0e4849eb878
multi
Tophi in gout found in all regions except
Ans. is 'b' i.e., Muscle Location of Tophi They are classically located along the helix of the ear. Can also be seen in :- Fingers Toes Prepattelar bursa Olecranon Although gout typically cuases joint inflammation, it can also cause inflammation in other synol-based structures, such as bursae and tendons. Tophi are col...
2
Prepatellar bursae
Muscle
Helix of ear
Synol membrane
Medicine
null
2efc4520-cef6-49ab-8eac-ff9557b543b8
multi
A mother comes with her 3 year old female child with complain of that child is not eating anything. Her weight is 11 kg (50th percentile) and height is 88 cm. (75th percentile). What should be done next –
"Allowable normal range of variation in observation, is conventionally taken between 3'd and 97th percentile curves"  -Ghai This female child has weight (50 th percentile) and height (75th percentile) in normal range of variation (3rd-97th percentile). So, nothing should be done actively and the parent should be assur...
3
Vitamin rich tonic to be given
Forceful eating
Nothing should be done actively and assure the parent
Complete investigation for UTI
Pediatrics
null
74cebd18-4025-4732-b117-fde9b4d81453
single
Fornication and delusion of persecution, both are together seen in -
This question is tricky one as tactile hallucination (fornication) and delusion of persecution are seen both in cocaine as well as amphetamine abuse. Read the question carefully, examiner has asked about the presence of fornication and delusion of persecution together. In amphetamine abuse these two do not occur togeth...
3
LSD psychosis
Amphetamine psychosis
Cocaine psychosis
Cannabis psychosis
Forensic Medicine
null
3f70d001-441a-4b6e-8499-b4120fb5f56d
multi
Lingual tonsils arise:
null
1
As developmental anomalies
From carcinomatous transformation
As a result of hyperplasia
Due to repeated trauma in the area
Pathology
null
52cb9242-2bc1-4e8f-9a9f-6651a0674322
single
IUCD must not be used in a woman with-
Pelvic tuberculosis is an absolute contraindication for IUD inseion. Absolute contraindications for IUD Relative contraindications for IUD Suspected Pregnancy PID Vaginal Bleeding of undiagnosed etiology Ca Cervix,Uterus or Adnexa and other pelvic tumours Previous Ectopic Pregnancy Anaemia Menorrhagia History of PID si...
2
Genital herpes with severe non-purulent discharge
Pelvic tuberculosis
AIDS on ARV therapy
Recto-vaginal fistula
Social & Preventive Medicine
Natural Methods, Barrier Methods, IUDs, OCPs
ddcf5f2f-c9a2-4c2e-ba72-904e1c5e2b78
single
All enveloped helical RNA viruses belong to one large group, which includes all of the following except:
Ans. d. Herpes
4
Influenza
Parainfluenza
Mumps
Herpes
Microbiology
null
2af68c98-1f39-4900-b275-515bebed135f
multi
Which toll like receptors are involved in action of bacterial endotoxins -
Ans. is 'b' i.e., II o Ten different mammalian Toll like receptors (TRRs) have been identified --> TLR 1 to 10. o TLRs are involved in responses to widely divergent types of molecules that are commonly expressed by microbial but not mammalian cells. TLR Microbial ligand molecules Peptidoglycan of Gram (+)ve bacteria zy...
2
I
II
III
V
Pathology
null
92e6d38b-7f7b-480d-b81e-07533d8f24d8
single