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2f6be3a1-0736-4ec3-9e42-aa9732e401d6
Kappa agonist and mu antagonist are:Pentazocine, nalbuphine, butarphanol.They are responsible for causing dysphoria as a side effect.Buprenorphine is paial mu agonist and kappa antagonist.Tramadol and fentanyl are synthetic opioids.
Pharmacology
AIIMS 2017
A patient presented with pain in the right lower quadrant of abdomen. He has history of renal stones in right kidney. He was prescribed an opioid which is agonist at kappa receptors and antagonist at mu receptors. The likely drug given was: A. Pentazocine B. Buprenorphine C. Tramadol D. Fentanyl
Pentazocine
53cc935b-3123-4b83-ad62-307b2b736c9e
Ans. C. PVPemphigus vulgaris (PV) is a rare and serious (potentially life-threatening) condition that causes painful blisters to develop on the skin and lining of the mouth, nose, throat and genitals.The blisters are fragile and can easily burst open, leaving areas of raw unhealed skin that are very painful and can put...
Skin
null
After sequential arrangement of blistering disorder staing from superficial to deep blisters, which is the deepest among these? A. IgA pemphigus B. EBD C. PV D. Bullous pemphigoid+
PV
22e57519-9267-43a7-888e-70bc373bc109
Ans: C. -PCR for rabies virusRef: Ananthanarayan 10/e p536, 8/e p529: Harrison 19/e p1302).Detection of rabies virus:-PCR with genetic sequencing:Highly sensitive & specific.Accurately identify rabies genome (viral RNA) in CSF, fresh saliva samples, corneal scrapings or urine.Distinguish among rabies virus variants.Per...
Microbiology
null
A patient presented to the hospital with severe hydrophobia. You suspect rabies, obtained corneal scrapings from the patient. What test should be done on this specimen for a diagnosis of rabies? A. Negri bodies B. Antibodies to rabies virus C. -PCR for rabies virus D. Indirect immunofluorescence
-PCR for rabies virus
739272d2-530b-4885-8178-0d785683b86e
It is not exactly 7.2% but it is the closest choice.
Pediatrics
null
Percentage of lactose in human milk is – A. 7.2gm B. 4.5gm C. 8.0gm D. 6.7gm
7.2gm
72440397-8eda-480d-8d46-67fada73ecdb
Multipennate: Having the fibers arranged at multiple angles in relation to the axis of force generation. E.g., Masseter.
Dental
null
Masseter is a strong muscle due to: A. Multipennate arrangement of fibers B. Bipennate arrangement of fibers C. Random arrangement of fibers D. Circumpennate arrangement of fibers
Multipennate arrangement of fibers
460ac269-4f1c-4305-b286-b5fd124289f8
Down's analysis provides information by which we can determine whether the individual’s pattern shows comparatively harmonious relations or not and whether dysplasia present in a person is in the facial skeleton, the dentition or in both. Steiner concluded that it might not be possible to correct dentition according to...
Dental
null
Which of the following cephalometric analysis does not reveal the severity of anteroposterior jaw dysplasia? A. Down's analysis B. Steiner analysis C. Tweed's analysis D. Wit's analysis
Tweed's analysis
7d01f5ce-d737-4838-bf15-68a4dea15b1a
Echinococcus multilocularis causes malignant hydatid disease in which Tumour are slow-growing And are alveoli like which is ill-defined ,slow-growing and invasive .It causes alveolar hydatidosis. Echinococcus granulosus causes hydatid disease in liver or cystic echinococcosis. Amoebic liver abscess is an extra intensti...
Microbiology
AIIMS 2019
Slow growing alveolar like tumor in liver A. E. granulosus B. E. multilocularis C. Cysticercus cellulosae D. Amoebic liver abscess
E. multilocularis
c67981e0-4b43-491d-b690-a58a5d46fc7f
Biomechanical Considerations The maxilla can be advanced 2-4 mm forward over a period of 8-12 months. The amount of maxillary movement is influenced by a number of factors like: Amount of force: Successful maxillary protraction can be brought about by 300-500 gm of force per side in the primary or mixed dentition. Dir...
Dental
null
Direction of force by class III elastic in face mask? A. 15-20 degree downward from occlusion B. 15-20 degree upward from occlusion C. 35-40 deg downward from occlusion D. 5-10 deg downword from occlusion
15-20 degree downward from occlusion
89954831-6a35-49a3-811d-95cd7edc2c7c
HbS mobility on gel electrophoresis:Decreased mobility - Compared to normal hemoglobin.Electrophoresis of hemoglobin:Obtained from lysed red blood cells.Used in sickle cell trait & disease diagnosis.Sequence of Movement: HbA2 < HbC < HhS < HbF < HbA
Biochemistry
null
After a point mutation, glutamic acid is replaced by valine, which leads to formation of sickle cell hemoglobin. The mobility of HbS as compared with normal hemoglobin on gel electrophoresis will be: A. Decreased B. Increased C. Dependent on HbS concentration D. Unchanged.
Decreased
83b776f2-ae9a-42ec-8262-931b29af2d9f
Answer- C. 2bThe severity, radiology and management of Necrotizing enterocolitis is best exemplified by the 'Modified Bell's stagingcrileria'- According to 'Modified Bell's staging criteria'pneumatosis poalis (Presinie of gas in pofiai vein) is suggestiveof stage 2b.
Pediatrics
null
A 3 days old baby is admitted with intraventricular hemorrhage. Baby develops abdominal distention. The X-ray abdomen showed pneumatosis poalis. Stage the necrotizing enterocolitis: A. lb B. 2a C. 2b D. 3a
2b
87fab9d2-9419-49c1-93bf-59d0a311e8de
Answer- A. Linagliptinlinagliptin has the ability to be safely dosed in chronic kidney disease patients. Chronic kidney disease is a major complication in type 2 diabetesLinagliptin .No dose required linagliptin for patients with renal impairment
Pharmacology
null
A 70 years old hypeensive patient with stage 5 chronic kidney disease was diagnosed recently with Type 2 diabetes mellitus. He doesn't want to take injectable insulin. Which of the following oral hypoglycemic agents will be preferred in this patient, which won't require any renal dose modification? A. Linagliptin B. Re...
Linagliptin
234d826f-4a7b-4fd1-9799-b1a3602355fe
Ans: D. Opioid poisoning(Ref: Harrison 19/e p 1774, 2583, 18/e p3295)Findings in question represents hallmark sign of opiate overdose.Opioid overdose triad:Decreased level of consciousness + Pinpoint pupils + Respiratory depression. .Other Signs & symptoms:Hypotension, Seizures & muscle spasms.All secretions are suspen...
Medicine
null
A 25 years old unidentified male from roadside was brought by police to emergency room with disorientation, altered sensorium and vomiting. He had a BP of 90/70 mm Hg, hea rate of 110/min, temperature -36.4degC and respiratory rate of 11/min. On examination, he had bilateral pin-point pupils. What is the most probable ...
Opioid poisoning
69f1a181-5580-4146-ba87-bbd3980f948c
Answer- C. Internal carotid aerySurgical ligation of vessels or embolization is the last reso to control epistaxis when all other methods fail. Internal carotid aery is not ligated in case of epistaxis control, as it is the msinvessel supplying the central nervous system."Endoscopy identifies the source of posterior ep...
ENT
null
Which of the following vessel is not ligated in case of epistaxis control? A. Maxillary aery B. Anterior ethmoidal aery C. Internal carotid aery D. External carotid aery
Internal carotid aery
20929b62-1d50-4e64-9370-8d4966ccb2ae
Ans. d. Carotico-cavernous fistula (Ref KANSKI7/E PG94; PARSON 20/E P455,462)The most likely diagnosis in a young adult with history of trauma to the eye with proptosis and pain in the right eye and bruise on the right eye and forehead is Carotico-cavernous fistula
Ophthalmology
null
A young adult presents 2 days after trauma to the eye with proptosis and pain in the right eye. On examination, hi is found to have a bruise on the right eye and forehead. The most likely diagnosis is: A. Fracture sphenoid bone B. Cavernous sinus thrombosis C. Internal carotid aery aneurysm D. Carotico-cavernous fistul...
Carotico-cavernous fistula
4566acfa-b637-4b16-9602-b7b88e4012d2
Ans: A. GnRH analogues(Ref- .Shaw 16/e p59).Precocious pubey - Treatment:Depends on cause.Primary treatment goal:Enable child to grow to a normal adult height.GnRH & Medroxy progesterone acetate.GnRH agonists:Doc regardless of cause.DOC for halting premature sexual development.Effective in children with organic brain l...
Gynaecology & Obstetrics
null
What is the drug of choice for precocious pubey in girls? A. GnRH analogues B. Cyproterone acetate C. Danazol D. Medroxyprogesterone acetate
GnRH analogues
edd2f617-40bb-4a40-9598-059172c2618f
Morphine (an opioid) is a strong analgesic. It is used in treatment of all types of pain like Crush injury, Fracture, MI, cancer pain, post-operative pain etc. However in Biliary colic (e.g. due to any stone blocking bile duct), morphine constricts sphincter of Oddi and increase the intrabiliary pressure. This increase...
Pharmacology
AIIMS 2018
Morphine should not be used in the treatment of:- A. Ischemic pain B. Biliary colic C. Cancer pain D. Post operative pain
Biliary colic
51234bc7-9170-45cc-8494-837fe23af441
Ans. A. Since there is a comparison between fat content of EBM in preterm vs term infant the best study design will be, Case control. Prospective Coho study will be appropriate if we want to see the change in the fat content of EBM in preterm infants.
Social & Preventive Medicine
null
A study is to be conducted with regards to the fat content in the expressed breast milk of pre-term infants as compared to term infants. Which study design is best suited? A. Case control B. Prospective coho C. Longitudinal study D. Ambispective
Case control
b0a05a95-cb2d-4ec4-9e19-c25742e18221
0 (Points) 1 2 Appearance Blue or pale all over Blue extremities, but torso pink Pink all over Pulse None <100 >100 Grimace No response Weak grimace when stimulated Cries or pulls away when stimulated Activity None Some flexion of arms Arms flexed, legs resist extension Respirations None Weak, irregular or gasping Stro...
Pediatrics
AIIMS 2017
APGAR acronym stands for? A. Activity, pulse pressure, grimace, appearance, rate of respiration B. Appearance, pressure, grimace, MAP, hea rate C. Appearance, pressure, grimace, appearance, rate of hea beat D. Appearance, pulse, grimace, activity, respiration
Appearance, pulse, grimace, activity, respiration
f07a7a11-ae84-4843-a8a2-9f77447fb954
Ans. A. Paracetamol Acute liver failure after administration of paracetamol at the maximum recommended daily dose in adults.Paracetamol is the most commonly used analgesic and antipyretic in the world; it can be bought without prescription in most countries despite being the commonest cause of acute liver failure in we...
Pharmacology
null
Most commonly implicated drug for acute liver failure is - A. Paracetamol B. Valproate C. Warfarin D. Tetracyclines
Paracetamol
0c49a620-48a0-4240-9754-acf9310cd53c
Answer- A (B- cell)MC type of cancer of the orbit in adultsUsually a form of B-cell non-Hodgkin's lymphomaIt may show up as a nodule in the eyelid or around the eye, or it may cause the eye to be pushed out.This type of eye cancer usually does not cause pain.
Pathology
null
Most common type of Non-Hodgkin's lymphoma in the orbit: A. B-cell B. T-cell C. NK-cell D. Plasma cell
B-cell