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Boltzmann distribution-In mathematics-In more general mathematical settings, the Boltzmann distribution is also known as the Gibbs measure. In statistics and machine learning, it is called a log-linear model. In deep learning, the Boltzmann distribution is used in the sampling distribution of stochastic neural networks...
milkshake721/2.1M-wiki-STEM
Boltzmann distribution-In economics-The Boltzmann distribution can be introduced to allocate permits in emissions trading. The new allocation method using the Boltzmann distribution can describe the most probable, natural, and unbiased distribution of emissions permits among multiple countries. The Boltzmann distributi...
milkshake721/2.1M-wiki-STEM
Sstream-Sstream-In the C++ programming language, <sstream> is a part of the C++ Standard Library. It is a header file that provides templates and types that enable interoperation between stream buffers and string objects.
milkshake721/2.1M-wiki-STEM
Carey Fineman Ziter syndrome-Carey Fineman Ziter syndrome-Carey Fineman Ziter syndrome is a rare genetic condition. Fewer than 10 cases have been reported in the literature.
milkshake721/2.1M-wiki-STEM
Carey Fineman Ziter syndrome-Signs and symptoms-Several features have been described in this syndrome. These include: cleft palate micrognathia laryngostenosis developmental delay small pons scoliosis myopathy intermittent episodes of hypertension Poland sequence Möbius sequence hydronephrosis bilateral clubfeet (talip...
milkshake721/2.1M-wiki-STEM
Carey Fineman Ziter syndrome-Genetics-Mutations in the gene Myomaker (MYMK) have been shown to be responsible for this condition. The gene is located on the long arm of chromosome 9 (9q34.2). Inheritance is autosomal recessive.
milkshake721/2.1M-wiki-STEM
Carey Fineman Ziter syndrome-Pathogenesis-The Myomaker gene encodes a transmembrane protein that is found on the surface of muscle cells. Mutations in this protein result in failure of myoblast fusion.
milkshake721/2.1M-wiki-STEM
Carey Fineman Ziter syndrome-Diagnosis-Diagnosis is made by sequencing the MYMK gene. Previously diagnosis could be made on clinical features, though brain anomalies could only be determined with an MRI. Differential diagnosis Native American myopathy Moebius syndrome
milkshake721/2.1M-wiki-STEM
Carey Fineman Ziter syndrome-Treatment-There is no curative treatment known. Management is supportive.
milkshake721/2.1M-wiki-STEM
Carey Fineman Ziter syndrome-History-The condition was first described in 1982.Jordan River Anderson, born in 1999 in and died in 2005, was diagnosed with Carey Fineman Ziter syndrome and lived his entire life in hospital in Winnipeg, Manitoba, Canada. There were plans for him to live outside hospital with family but f...
milkshake721/2.1M-wiki-STEM
Filters, random fields, and maximum entropy model-Filters, random fields, and maximum entropy model-In the domain of physics and probability, the filters, random fields, and maximum entropy (FRAME) model is a Markov random field model (or a Gibbs distribution) of stationary spatial processes, in which the energy functi...
milkshake721/2.1M-wiki-STEM
Filters, random fields, and maximum entropy model-Filters, random fields, and maximum entropy model-The original FRAME model is homogeneous for texture modeling. Xie et al. proposed the sparse FRAME model, which is an inhomogeneous generalization of the original FRAME model, for the purpose of modeling object patterns,...
milkshake721/2.1M-wiki-STEM
Filters, random fields, and maximum entropy model-Filters, random fields, and maximum entropy model-The deep FRAME model is a deep generalization of the original FRAME model. Instead of using linear filters as in the original FRAME model, Lu et al. uses the filters at a certain convolutional layer of a pre-learned Conv...
milkshake721/2.1M-wiki-STEM
Call-by-push-value-Call-by-push-value-In programming language theory, the call-by-push-value (CBPV) paradigm, inspired by monads, allows writing semantics for lambda-calculus without writing two variants to deal with the difference between call-by-name and call-by-value. To do so, CBPV introduces a term language that d...
milkshake721/2.1M-wiki-STEM
Call-by-push-value-Call-by-push-value-This is especially useful when dealing with the semantics of different side effects, such as nontermination, mutable state or nondeterminism. Instead of giving two variants of the semantics, one for the call-by-name evaluation order and one for the call-by-value one, one can simply...
milkshake721/2.1M-wiki-STEM
Encirclement-Encirclement-Encirclement is a military term for the situation when a force or target is isolated and surrounded by enemy forces. The situation is highly dangerous for the encircled force. At the strategic level, it cannot receive supplies or reinforcements, and on the tactical level, the units in the forc...
milkshake721/2.1M-wiki-STEM
Encirclement-History-Encirclement has been used throughout the centuries by military leaders, including generals such as Spartacus, Alexander the Great, Julius Caesar, Genghis Khan, Khalid bin Waleed, Hannibal, Sun Tzu, Yi Sun Shin, Shaka Zulu, von Wallenstein, Nader Shah, Napoleon, von Moltke, Heinz Guderian, von Rund...
milkshake721/2.1M-wiki-STEM
Encirclement-History-Sun Tzu and other military thinkers suggest that an army should be not completely encircled but instead given some room for escape. Otherwise, the "encircled" army's men will lift their morale and fight to the death. It is better to have them consider the possibility of a retreat. Once the enemy re...
milkshake721/2.1M-wiki-STEM
Encirclement-Types of encirclement-The main form of encircling, the "double pincer", is executed by attacks on the flanks of a battle whose mobile forces of the era, such as light infantry, cavalry, tanks, or armoured personnel carriers attempt to force a breakthrough to utilize their speed to join behind the back of t...
milkshake721/2.1M-wiki-STEM
Encirclement-Types of encirclement-A third and rare type of encirclement can ensue from a breakthrough in an area of the enemy front, and exploiting that with mobile forces, diverging in two or more directions behind the enemy line. Full encirclement rarely follows, but the threat of it severely hampers the defender's ...
milkshake721/2.1M-wiki-STEM
Encirclement-Types of encirclement-The danger to the encircling force is that it is, itself, cut off from its logistical base; if the encircled force is able to stand firm, or maintain a supply route, the encircling force can be thrown into confusion (for example, Rommel's "Dash to the Wire" in 1941 and the Demyansk Po...
milkshake721/2.1M-wiki-STEM
Encirclement-Notable encirclement battles-Some examples of battles of encirclement are listed below.
milkshake721/2.1M-wiki-STEM
Encirclement-Notable encirclement battles-Battle of Thermopylae (480 BC) Battle of Cannae (216 BC) Battle of the Abas (65 BC) Battle of Walaja (633 AD) Battle of Ekeren (1703) Battle of Fraustadt (1706) Battle of Kirkuk (1733) Battle of Kars (1745) Battle of Maymyo (1768) Ulm Campaign (1805) Battle of Ocaña (1809) Batt...
milkshake721/2.1M-wiki-STEM
Cyanoacetylene-Cyanoacetylene-Cyanoacetylene is an organic compound with formula C3HN or H−C≡C−C≡N. It is the simplest cyanopolyyne. Cyanoacetylene has been detected by spectroscopic methods in interstellar clouds, in the coma of comet Hale–Bopp and in the atmosphere of Saturn's moon Titan, where it sometimes forms exp...
milkshake721/2.1M-wiki-STEM
Nabkha-Nabkha-A nabkha, nebkha or nebka is a type of sand dune. Other terms used include coppice dune and dune hummock or hummocky dune, but these more accurately refer to similar, but different, sand dune types. Authors have also used the terms phytogenic hillock, bush-mound, shrub-coppice dune, knob dune, dune tumulu...
milkshake721/2.1M-wiki-STEM
Nabkha-Structure-Many species of sand-dwelling plants form nabkhas. In the Chihuahuan Desert they include soaptree (Yucca elata), creosote (Larrea tridentata), and atriplex (Atriplex spp.). In China nabkhas form quite often around Caragana microphylla, as well as Cleistogenes squarrosa, Leymus chinensis, Caragana steno...
milkshake721/2.1M-wiki-STEM
Nabkha-Ecology-Nabkhas are common features in landscapes that are undergoing desertification. In North America, a characteristic sign of desertification is the spread of mesquites (Prosopis spp.) into the habitat. Mesquites rapidly accumulate windblown sand, forming nabkhas. In northern China, nabkhas were present on g...
milkshake721/2.1M-wiki-STEM
Nabkha-Etymology-Nabkha is an Arabic word that has been in use for at least 14 centuries. It translates roughly to "small, sandy hillock".
milkshake721/2.1M-wiki-STEM
Papulonecrotic tuberculid-Papulonecrotic tuberculid-Papulonecrotic tuberculid is usually an asymptomatic, chronic skin disorder, presenting in successive crops, skin lesions symmetrically distributed on the extensor extremities.: 337
milkshake721/2.1M-wiki-STEM
Shades of magenta-Shades of magenta-The color magenta has notable tints and shades. These various colors are shown below.
milkshake721/2.1M-wiki-STEM
Shades of magenta-Definition of magenta-Magenta is a color made up of equal parts of red and blue light. This would be the precise definition of the color as defined for computer display (the color #FF00FF shown in the color swatch above). It is a pure chroma on the RGB color wheel (Image of RGB color wheel:) midway be...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Definition of magenta-In a color proximity sense, a primary color has a color range of 120° (60° on each side of the color's hue) and any color has to be within that range to be considered a variation of that color. Secondary colors have a color range of 60° (30°), tertiary colors have a color range o...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Definition of magenta-Magenta is not a spectral but an extraspectral color: it cannot be generated by light of a single wavelength. Humans, being trichromats, can only see as far as 380 nanometers into the spectrum, i.e., as far as violet. The hue magenta is the complement of green: magenta pigments a...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Three major historical variations of magenta-Magenta dye (original variation) (1860) Before printer's magenta was invented in the 1890s for CMYK printing, and electric magenta was invented in the 1980s for computer displays, these two artificially engineered colors were preceded by the color displayed...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Three major historical variations of magenta-Process magenta (pigment magenta) (printer's magenta) (1890s) In color printing, the color called process magenta or pigment magenta is one of the three primary pigment colors which, along with yellow and cyan, constitute the three subtractive primary color...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Three major historical variations of magenta-Process magenta is not an RGB color, and there is no fixed conversion from CMYK primaries to RGB. Different formulations are used for printer's ink, so there can be variations in the printed color that is pure magenta ink. A typical formulation of process m...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Three major historical variations of magenta-Web colors magenta and fuchsia (1990s) Magenta, shown at the right, is one of the three secondary colors in the RGB color model, used to make all the colors on computer and television displays. It is made by a mixture of red and blue light at equal intensit...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Additional variations of magenta-Magenta (Pantone) Displayed at right is the color magenta (Pantone), i.e., the color that is called magenta in the Pantone color system. The source of this color is the "Pantone Textile Paper eXtended (TPX)" color list, color #17-2036 TPX—Magenta. Magenta (Crayola) At ...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Additional variations of magenta-Sky magenta Displayed at right is the color sky magenta. The color sky magenta is a representation of the color of the sky near the Sun during the brief period during twilight when the pink of sunset transitions into the blue of early evening. This color was one of the...
milkshake721/2.1M-wiki-STEM
Shades of magenta-Additional variations of magenta-This color is also called medium lavender pink. A photograph of the sky displaying the color sky magenta in its natural context by photographer Dave Horne [3] is displayed here: [4] Telemagenta Displayed at right is the color telemagenta. This is one of the colors in t...
milkshake721/2.1M-wiki-STEM
Pitting resistance equivalent number-Pitting resistance equivalent number-Pitting resistance equivalent number (PREN) is a predictive measurement of a stainless steel's resistance to localized pitting corrosion based on its chemical composition. In general: the higher PREN-value, the more resistant is the stainless ste...
milkshake721/2.1M-wiki-STEM
Pitting resistance equivalent number-PREN formulas (w/w)-There are several PREN formulas. They commonly range from: PREN = %Cr + 3.3 × %Mo + 16 × %Nto: PREN = %Cr + 3.3 × %Mo + 30 × %N.There are a few stainless steels which add tungsten (W), for those the following formula is used: PREN = %Cr + 3.3 × (%Mo + 0.5 × %W ...
milkshake721/2.1M-wiki-STEM
Pitting resistance equivalent number-Pitting resistance measurement-Exact pitting test procedures are specified in the ASTM G48 standard.
milkshake721/2.1M-wiki-STEM
Fitocracy-Fitocracy-Fitocracy is an online game and social network that aims to use gamification to help users improve their fitness. It has received coverage from mainstream media sources.
milkshake721/2.1M-wiki-STEM
Fitocracy-History-Fitocracy was founded by Dick Talens and Brian Wang. Both were self-described computer nerds who had succeeded in improving their own fitness and decided that game mechanics could help others to do the same.Fitocracy launched in February 2011, using an invite system to control new user signups. Invite...
milkshake721/2.1M-wiki-STEM
Fitocracy-History-In March 2013, Fitocracy reached one million users and announced a collaboration with Arnold Schwarzenegger, which challenges users to exercise for 15 minutes per day.In August 2014, Fitocracy was listed as one of Time's Best Websites of 2014.Fitocracy was acquired in 2016 by an unnamed buyer.In Octob...
milkshake721/2.1M-wiki-STEM
Fitocracy-Game-Fitocracy users log their exercise activity by selecting from a collection of activities such as weight lifting or running and entering details such as weight lifted or distance run. Points are awarded based on the estimated fitness benefit of each activity. Users must reach points thresholds in order to...
milkshake721/2.1M-wiki-STEM
Fitocracy-Reception-Fitocracy was initially covered by technology and gaming focused media, such as TechCrunch, Slate, Lifehacker, Kotaku, and Destructoid. As it grew, it was covered by more mainstream media, including Popular Mechanics, The New York Observer, CNN, The New York Times and The Globe and Mail. 2012 Shorty...
milkshake721/2.1M-wiki-STEM
Rumble (noise)-Rumble (noise)-A rumble is a continuous deep, resonant sound, such as the sound made by heavy vehicles or thunder. In the context of audio reproduction rumble refers to a low frequency sound from the bearings inside a turntable. This is most noticeable in low quality turntables with ball bearings. Higher...
milkshake721/2.1M-wiki-STEM
Rumble (noise)-Turntable design-One way to reduce rumble is to make the turntable very heavy, so that it acts as mechanical damper or low-pass filter, but even with the best turntables a lot of rumble tends to be generated by warped records or pressing irregularities sometimes visible as ‘bobbles’ in the surface. An im...
milkshake721/2.1M-wiki-STEM
Rumble (noise)-Rumble filters-Because these effects generate a mostly vertical component at the stylus, which corresponds to a difference signal in stereo reproduction, the incorporation of a high-pass filter operating only on the channel difference can be very effective in reducing rumble without loss of bass. Such a ...
milkshake721/2.1M-wiki-STEM
Rumble (noise)-Rumble filters-Though several standards exist that define how rumble should be measured, they all have a common basis, and use the weighting curves shown here. DIN 45539 (1971) and IEC98-1964 both cover rumble measurement. BS4852: Part 1 (1972) is specific in requiring that a slow rectifier be used, whic...
milkshake721/2.1M-wiki-STEM
CLOUD experiment-CLOUD experiment-Cosmics Leaving Outdoor Droplets (CLOUD) is an experiment being run at CERN by a group of researchers led by Jasper Kirkby to investigate the microphysics between galactic cosmic rays (GCRs) and aerosols under controlled conditions. This is a fixed-target experiment that began operatio...
milkshake721/2.1M-wiki-STEM
CLOUD experiment-Setup-The core of the experiment is a stainless steel chamber of 26m³ volume filled with synthetic air made from liquid nitrogen and liquid oxygen. The chamber atmosphere and pressure is being measured and regulated by various instrumentations. The aerosol chamber can be exposed to an adjustable partic...
milkshake721/2.1M-wiki-STEM
CLOUD experiment-Results-CERN posted a 2009 progress report on the CLOUD project. J. Kirkby (2009) reviews developments in the CERN CLOUD project and planned tests. He describes cloud nucleation mechanisms which appear energetically favourable and depend on GCRs.On 24 August 2011, preliminary research published in the ...
milkshake721/2.1M-wiki-STEM
Novikov's condition-Novikov's condition-In probability theory, Novikov's condition is the sufficient condition for a stochastic process which takes the form of the Radon–Nikodym derivative in Girsanov's theorem to be a martingale. If satisfied together with other conditions, Girsanov's theorem may be applied to a Brown...
milkshake721/2.1M-wiki-STEM
Novikov's condition-Novikov's condition-This condition was suggested and proved by Alexander Novikov. There are other results which may be used to show that the Radon–Nikodym derivative is a martingale, such as the more general criterion Kazamaki's condition, however Novikov's condition is the most well-known result. A...
milkshake721/2.1M-wiki-STEM
Bucherer carbazole synthesis-Bucherer carbazole synthesis-The Bucherer carbazole synthesis is a chemical reaction used to synthesize carbazoles from naphthols and aryl hydrazines using sodium bisulfite. The reaction is named after Hans Theodor Bucherer.
milkshake721/2.1M-wiki-STEM
Isolichenan-Isolichenan-Isolichenan, also known as isolichenin, is a cold-water-soluble α-glucan occurring in certain species of lichens. This lichen product was first isolated as a component of an extract of Iceland moss in 1813, along with lichenin. After further analysis and characterization of the individual compon...
milkshake721/2.1M-wiki-STEM
Isolichenan-Early studies-Isolichenan was first isolated from Cetraria islandica in 1813 by Swedish chemist Jöns Jacob Berzelius, who also at the same time isolated the cellulose-like hot-water-soluble glucan lichenan. Because in these experiments the isolichenan component of the lichen extract had a positive reaction ...
milkshake721/2.1M-wiki-STEM
Isolichenan-Structure-Isolichenan is a polymer of glucose units joined by a mixture of α-(1→3) and α-(1→4) linkages. Using the technique of partial acid hydrolysis, Stanley Peat and colleagues determined that the linkages are of the α-configuration. The ratio of these linkages has been reported differently by various a...
milkshake721/2.1M-wiki-STEM
Isolichenan-Occurrence-Since its discovery in Cetraria islandica, isolichenan has been isolated from many other lichen species. It is predominant in the Parmeliaceae, a large and diverse family of the class Lecanoromycetes. Parmeliaceae genera and species containing isolichenan include: Alectoria (A. sulcata, A. sarmen...
milkshake721/2.1M-wiki-STEM
Isolichenan-Uses-Although isolichenan is not nearly as constant at the genus level as lichenan, the presence of isolichenan in the cell walls is a defining character in several genera of the lichen family Parmeliaceae, including Asahinea, Cetrelia, Flavoparmelia, and Psiloparmelia. In contrast, the absence of isolichen...
milkshake721/2.1M-wiki-STEM
Isolichenan-Research-Isolichenan was shown to enhance hippocampal plasticity and behavioural performance in rats. When administered orally, isolichenan was also shown to improve memory acquisition in mice impaired by ethanol, as well as in rats in which memory impairment had been induced by beta-amyloid peptide. In mor...
milkshake721/2.1M-wiki-STEM
The Enchanter Completed-The Enchanter Completed-The Enchanter Completed (or a variant thereof) is a title that has been given to two separate books relating to the fiction of science fiction and fantasy writer L. Sprague de Camp: The Enchanter Compleated, a 1980 edition of the collection originally and more usually tit...
milkshake721/2.1M-wiki-STEM
Sexual arousal disorder-Sexual arousal disorder-Sexual arousal disorder is characterized by a lack or absence of sexual fantasies and desire for sexual activity in a situation that would normally produce sexual arousal, or the inability to attain or maintain typical responses to sexual arousal. The disorder is found in...
milkshake721/2.1M-wiki-STEM
Sexual arousal disorder-Signs and symptoms-In women, the symptoms of the disorder include: Lack of vaginal lubrication Lack of vaginal dilation or lengthening Decreased genital tumescence or swelling Decreased genital or nipple sensationHowever, whether lack of physiological arousal is a reliable symptom of the disorde...
milkshake721/2.1M-wiki-STEM
Sexual arousal disorder-Causes-Contrary to popular belief, the disorder is not always caused from a lack of sexual arousal. Possible causes of the disorder include psychological and emotional factors, such as depression, anger, and stress; relationship factors, such as conflict or lack of trust; medical factors, such a...
milkshake721/2.1M-wiki-STEM
Sexual arousal disorder-Causes-Certain medications like SSRIs may contribute to a loss of sexual arousal, either while taking the medication or during withdrawal. In seemingly rare cases, SSRIs have been reported to cause an reduction in sexual arousal that last months or years after discontinuation, a condition termed...
milkshake721/2.1M-wiki-STEM
Sexual arousal disorder-Diagnosis-A psychologist will first consider any psychological or emotional problems; while a sex therapist will examine relationship issues; after which a medical doctor will investigate medical causes for the disorder. In order to receive this diagnosis, a woman must, for at least 6 months, re...
milkshake721/2.1M-wiki-STEM
Sexual arousal disorder-Treatment-Depending on the cause of the disorder, hormone therapy or a blood-flow enhancing medication, like Viagra, may be appropriate.
milkshake721/2.1M-wiki-STEM
Sexual arousal disorder-Treatment-Bremelanotide (formerly PT-141) is being studied in clinical tests to increase sexual desire in women. In 2014, Palatin, the company developing the drug, announced the beginning of a Phase 3 clinical trial to determine its effectiveness.Vibrators have also been found to be effective at...
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Furuta pendulum-The Furuta pendulum, or rotational inverted pendulum, consists of a driven arm which rotates in the horizontal plane and a pendulum attached to that arm which is free to rotate in the vertical plane. It was invented in 1992 at Tokyo Institute of Technology by Katsuhisa Furuta and his col...
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Equations of motion-Despite the great deal of attention the system has received, very few publications successfully derive (or use) the full dynamics. Many authors have only considered the rotational inertia of the pendulum for a single principal axis (or neglected it altogether). In other words, the in...
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Equations of motion-A few authors have considered slender symmetric pendulums where the moments of inertia for two of the principal axes are equal and the remaining moment of inertia is zero. Of the dozens of publications surveyed for this wiki only a single conference paper and journal paper were found...
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Equations of motion-The equations of motion presented here are an extract from a paper on the Furuta pendulum dynamics derived at the University of Adelaide.
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Equations of motion-Definitions Consider the rotational inverted pendulum mounted to a DC motor as shown in Fig. 1. The DC motor is used to apply a torque τ1 to Arm 1. The link between Arm 1 and Arm 2 is not actuated but free to rotate. The two arms have lengths L1 and L2 . The arms have masses m1 a...
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Equations of motion-A right hand coordinate system has been used to define the inputs, states and the Cartesian coordinate systems 1 and 2. The coordinate axes of Arm 1 and Arm 2 are the principal axes such that the inertia tensors are diagonal.
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Equations of motion-The angular rotation of Arm 1, θ1 , is measured in the horizontal plane where a counter-clockwise direction (when viewed from above) is positive. The angular rotation of Arm 2, θ2 , is measured in the vertical plane where a counter-clockwise direction (when viewed from the front) i...
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Equations of motion-Assumptions Before deriving the dynamics of the system a number of assumptions must be made. These are: The motor shaft and Arm 1 are assumed to be rigidly coupled and infinitely stiff. Arm 2 is assumed to be infinitely stiff. The coordinate axes of Arm1 and Arm 2 are the principal a...
milkshake721/2.1M-wiki-STEM
Furuta pendulum-Equations of motion-Non-linear Equations of Motion The non-linear equations of motion are given by sin cos cos sin sin ⁡(2θ2)(m2l22+J2yy−J2xx)+b1θ˙1=τ1 and cos sin sin ⁡(θ2)=τ2 Simplifications Most Furuta pendulums tend to have long slender arms, such that the moment of inertia along the axis of the arm...
milkshake721/2.1M-wiki-STEM
Autoimmune polyendocrine syndrome type 1-Autoimmune polyendocrine syndrome type 1-Autoimmune polyendocrine syndrome type 1 (APS-1), is a subtype of autoimmune polyendocrine syndrome (autoimmune polyglandular syndrome). It causes the dysfunction of multiple endocrine glands due to autoimmunity. It is a genetic disorder,...
milkshake721/2.1M-wiki-STEM
Autoimmune polyendocrine syndrome type 1-Signs and symptoms-APS-1 tends to cause severe symptoms. These are present from early in life, usually around 3.5 years of age. Common symptoms of APS-1 include: Chronic mucocutaneous candidiasis. Hypoparathyroidism. Addison's disease. Ectodermal dystrophy (skin, dental enamel, ...
milkshake721/2.1M-wiki-STEM
Autoimmune polyendocrine syndrome type 1-Cause-APS-1 is caused by a mutation in the AIRE gene, encoding a protein called autoimmune regulator. This is found on the 21q22.3 chromosome location, hence chromosome 21. The AIRE gene may be affected by any of at least 90 mutations. Mutations may be inherited in an autosomal ...
milkshake721/2.1M-wiki-STEM
Autoimmune polyendocrine syndrome type 1-Pathophysiology-APS-1 is due to problems with immune tolerance. APS-1 causes considerable reactions with both interferon omega and interferon alpha. There may also be a reaction against interleukin 22. This leads to damage to endocrine organs. Common problems include hypercalcae...
milkshake721/2.1M-wiki-STEM
Autoimmune polyendocrine syndrome type 1-Diagnosis-Diagnosis of APS-1 is based on a number of tests, including endoscopy, a CT scan, a biopsy (with histological testing), and serum endocrine autoantibody screening.
milkshake721/2.1M-wiki-STEM
Autoimmune polyendocrine syndrome type 1-Treatment-Autoimmune polyendocrine syndrome type 1 treatment is based on the symptoms that are presented by the affected individual. Treatments may involve hormone therapy, systemic antifungal treatments, and immunosuppression.
milkshake721/2.1M-wiki-STEM
Autoimmune polyendocrine syndrome type 1-History-APS-1 may also be known as autoimmunity endocrinopathy candidiasis ectodermal dystrophy / dysplasia (APECED), autoimmune polyglandular syndrome type 1, Whitaker syndrome, or candidiasis-hypoparathyroidism-Addison's disease syndrome.
milkshake721/2.1M-wiki-STEM
Pedro Portugal-Pedro Portugal-Pedro Portugal (Castelo Branco, 12 August 1963) is a Portuguese artist, with a wide production.
milkshake721/2.1M-wiki-STEM
Pedro Portugal-Life-Early Years His first individual exhibition was in 1985, the year he finished his painting course. At this exhibition he presented small pastel and oil paintings, already pregnant with a figurative stylizing code or, more generically, a signal system that is reportable to comics and cartoons. Coming...
milkshake721/2.1M-wiki-STEM
Pedro Portugal-Life-'90s Pedro Portugal is, in fact, not just a painter, he is a cultural "agitator". By the end of the 80s his work became more ample and explicit in as far as its critical commentary was concerned. It focused on the artistic, cultural, social and political state of affairs. As a prime example of the ...
milkshake721/2.1M-wiki-STEM
Pedro Portugal-Life-Throughout the 90s, the artist's horizon became more diversified in terms of workable materials. One could witness an emphasis on installations that were created for very specific purposes. In terms of social intentions, it funneled down to ecological concerns and political criticism. And, finally, ...
milkshake721/2.1M-wiki-STEM
Pedro Portugal-Life-Explainism and later years In 2007 he began the theoretical and artistic movement "Explainism" in collaboration with Pedro Proença. Thus, the artist dedicates himself in a multifaceted way to the ever-present question of the end of painting and of its aesthetic cultural tradition.
milkshake721/2.1M-wiki-STEM
Bracht–Wachter bodies-Bracht–Wachter bodies-Bracht–Wachter bodies are a finding in infective endocarditis consisting of yellow-white miliary spots in the myocardium. Histologically, these are collections of chronic inflammatory cells, mainly lymphocytes and histiocytes.
milkshake721/2.1M-wiki-STEM
Bracht–Wachter bodies-History-They were described by two Germans, Erich Franz Eugen Bracht, a pathologist and obstetrician-gynecologist, and Hermann Julius Gustav Wächter, a physician.
milkshake721/2.1M-wiki-STEM
Bracht–Wachter bodies-Related findings-Other findings in infective endocarditis are: Osler's nodes Janeway lesions Roth's spots Flea-bitten kidneys- pyemic spots
milkshake721/2.1M-wiki-STEM
Horse opera-Horse opera-A horse opera, hoss opera, oat opera or oater is a Western film or television series that is clichéd or formulaic, in the manner of a (later) soap opera or space opera.The term, which was originally coined by silent film-era Western star William S. Hart, is used variously to convey either dispar...
milkshake721/2.1M-wiki-STEM
Latent autoimmune diabetes in adults-Latent autoimmune diabetes in adults-Slowly evolving immune-mediated diabetes, or latent autoimmune diabetes in adults (LADA), is a form of diabetes that exhibits clinical features similar to both type 1 diabetes (T1D) and type 2 diabetes (T2D), and is sometimes referred to as type ...
milkshake721/2.1M-wiki-STEM
Latent autoimmune diabetes in adults-Latent autoimmune diabetes in adults-The concept of LADA was first introduced in 1993, though The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus does not recognize the term, instead including it under the standard definition of diabetes mellitus type 1.
milkshake721/2.1M-wiki-STEM
Latent autoimmune diabetes in adults-Symptoms-The symptoms of latent autoimmune diabetes in adults are similar to those of other forms of diabetes: polydipsia (excessive thirst and drinking), polyuria (excessive urination), and often blurred vision. Compared to juvenile type 1 diabetes, the symptoms develop comparative...
milkshake721/2.1M-wiki-STEM