slug stringlengths 3 55 | topic stringlengths 22 84 | url stringlengths 23 75 | canonical_name stringlengths 3 53 | category stringclasses 29
values | alternate_names listlengths 0 12 | datePublished timestamp[s]date 2026-06-15 00:00:00 2026-07-18 00:00:00 | dateModified timestamp[s]date 2026-06-15 00:00:00 2026-07-18 00:00:00 | lastReviewed timestamp[s]date 2026-06-15 00:00:00 2026-07-18 00:00:00 | conclusion stringlengths 1.17k 1.77k | citation listlengths 0 21 | markdown stringlengths 33k 55.9k |
|---|---|---|---|---|---|---|---|---|---|---|---|
3haa | 3HAA for Health & Longevity | https://evipedia.ai/3haa | 3HAA | compound | [
"3-Hydroxyanthranilic Acid",
"3-HAA",
"3HANA",
"2-Amino-3-hydroxybenzoic acid"
] | 2026-06-25T00:00:00 | 2026-06-25T00:00:00 | 2026-06-25T00:00:00 | 3HAA is a small molecule the body naturally makes when it breaks down a dietary protein building block. Long dismissed as a throwaway step, it has drawn fresh attention because raising its levels made laboratory worms and mice live longer and stay healthier, and because the same molecule rises in people's blood after m... | [
{
"name": "On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging",
"url": "https://pubmed.ncbi.nlm.nih.gov/38097593/",
"pmid": "38097593"
},
{
"name": "3-Hydroxyanthranilic Acid Delays Paralysis in Caenorhabditis elegans Models of Amyloi... | ---
canonical_name: 3HAA
alternate_names: 3-Hydroxyanthranilic Acid, 3-HAA, 3HANA, 2-Amino-3-hydroxybenzoic acid
canonical_topic: 3HAA for Health & Longevity
short_topic_lc: 3haa
creation_date: 2026-0625-1328
creator_ai_fullname: Opus 4.8
ep_keywords: Kynurenine Pathway Metabolites, Tryptophan Catabolites, Tryptophan M... |
40_hz_ultrasound | 40 Hz Ultrasound for Health & Longevity | https://evipedia.ai/40_hz_ultrasound | 40 Hz Ultrasound | brain | [
"40 Hz Transcranial Ultrasound Stimulation",
"40 Hz Pulsed Ultrasound",
"Gamma-Frequency Ultrasound",
"40 Hz Transcranial Focused Ultrasound",
"40 Hz TUS",
"Gamma-Entrainment Ultrasound"
] | 2026-07-04T00:00:00 | 2026-07-04T00:00:00 | 2026-07-04T00:00:00 | 40 Hz ultrasound is an early-stage, non-invasive idea: gentle sound-wave energy aimed through the skull and pulsed forty times a second to nudge the brain's fast "gamma" rhythm, with the hope of clearing sticky plaques, calming inflammation, and supporting memory as the brain ages. Its distinctive promise is reaching d... | [
{
"name": "Gamma oscillations and application of 40-Hz audiovisual stimulation to improve brain function",
"url": "https://pubmed.ncbi.nlm.nih.gov/36374520/",
"pmid": "36374520"
},
{
"name": "Effects of transcranial ultrasound stimulation pulsed at 40 Hz on Aβ plaques and brain rhythms in 5×FAD ... | ---
canonical_name: 40 Hz Ultrasound
alternate_names: 40 Hz Transcranial Ultrasound Stimulation, 40 Hz Pulsed Ultrasound, Gamma-Frequency Ultrasound, 40 Hz Transcranial Focused Ultrasound, 40 Hz TUS, Gamma-Entrainment Ultrasound
canonical_topic: 40 Hz Ultrasound for Health & Longevity
short_topic_lc: 40_hz_ultrasound
c... |
5_amino_1mq | 5-Amino-1MQ for Health & Longevity | https://evipedia.ai/5_amino_1mq | 5-Amino-1MQ | compound | [
"5-Amino-1-methylquinolinium",
"5-AMQ",
"5A1MQ",
"5-Amino-1-methylquinoline"
] | 2026-07-15T00:00:00 | 2026-07-15T00:00:00 | 2026-07-15T00:00:00 | 5-Amino-1MQ is a purpose-built small molecule that blocks an enzyme, NNMT, which becomes overactive in fat tissue and aging muscle. By doing so, it helps cells hold onto more of the fuel-and-repair molecule NAD⁺ and the body's main methyl donor, nudging cells to burn fat rather than store it. In obese mice it reduced f... | [
{
"name": "Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice",
"url": "https://pubmed.ncbi.nlm.nih.gov/29155147/",
"pmid": "29155147"
},
{
"name": "Nicotinamide N-methyltransferase (NNMT): a novel therapeu... | ---
canonical_name: 5-Amino-1MQ
alternate_names: 5-Amino-1-methylquinolinium, 5-AMQ, 5A1MQ, 5-Amino-1-methylquinoline
canonical_topic: 5-Amino-1MQ for Health & Longevity
short_topic_lc: 5_amino_1mq
creation_date: 2026-0715-0250
creator_ai_fullname: Opus 4.8
---
# 5-Amino-1MQ for Health & Longevity
<section id="top" ma... |
5_htp | 5-HTP for Health & Longevity | https://evipedia.ai/5_htp | 5-HTP | compound | [
"5-Hydroxytryptophan",
"Oxitriptan",
"L-5-Hydroxytryptophan",
"L-5-HTP",
"Griffonia simplicifolia Extract"
] | 2026-06-18T00:00:00 | 2026-06-18T00:00:00 | 2026-06-18T00:00:00 | 5-HTP is a serotonin-building compound, taken from an African seed and sold over the counter, that is widely used to support calm mood, better sleep, and reduced appetite. The most credible evidence points to modest help with sleep in people who already sleep poorly, and a plausible but unsettled effect on low mood; si... | [
{
"name": "Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan",
"url": "https://pubmed.ncbi.nlm.nih.gov/16023217/",
"pmid": "16023217"
},
{
"name": "5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects",
"url": "https://pubmed.n... | ---
canonical_name: 5-HTP
alternate_names: 5-Hydroxytryptophan, Oxitriptan, L-5-Hydroxytryptophan, L-5-HTP, Griffonia simplicifolia Extract
canonical_topic: 5-HTP for Health & Longevity
short_topic_lc: 5_htp
creation_date: 2026-0618-0340
creator_ai_fullname: Opus 4.8
ep_keywords: Serotonin Precursors, Amino Acid Deriva... |
78_dihydroxyflavone | 7,8-Dihydroxyflavone for Health & Longevity | https://evipedia.ai/78_dihydroxyflavone | 7,8-Dihydroxyflavone | compound | [
"7,8-DHF",
"Tropoflavin"
] | 2026-06-20T00:00:00 | 2026-06-20T00:00:00 | 2026-06-20T00:00:00 | "7,8-Dihydroxyflavone is a small plant-derived molecule designed to switch on the same brain recepto(...TRUNCATED) | [{"name":"7,8-Dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-(...TRUNCATED) | "---\ncanonical_name: 7,8-Dihydroxyflavone\nalternate_names: 7,8-DHF, Tropoflavin\ncanonical_topic: (...TRUNCATED) |
9_methyl_carboline | 9-Methyl-β-Carboline for Health & Longevity | https://evipedia.ai/9_methyl_carboline | 9-Methyl-β-Carboline | compound | [
"9-Me-BC",
"9-MBC",
"9-Methylnorharman",
"9-Methyl-9H-pyrido[3,4-b]indole"
] | 2026-07-16T00:00:00 | 2026-07-16T00:00:00 | 2026-07-16T00:00:00 | "9-Methyl-β-Carboline is an experimental compound from a chemical family better known for harming b(...TRUNCATED) | [{"name":"Stimulation, protection and regeneration of dopaminergic neurons by 9-methyl-β-carboline:(...TRUNCATED) | "---\ncanonical_name: 9-Methyl-β-Carboline\nalternate_names: \"9-Me-BC, 9-MBC, 9-Methylnorharman, 9(...TRUNCATED) |
acarbose | Acarbose for Health & Longevity | https://evipedia.ai/acarbose | Acarbose | medication | [
"Precose",
"Glucobay",
"Prandase",
"Acarbosum",
"BAY g 5421"
] | 2026-07-03T00:00:00 | 2026-07-03T00:00:00 | 2026-07-03T00:00:00 | "Acarbose is a long-approved diabetes medication that works entirely in the gut, slowing the digesti(...TRUNCATED) | [{"name":"A systematic review, meta-analysis, dose-response, and meta-regression of the effects of a(...TRUNCATED) | "---\ncanonical_name: Acarbose\nalternate_names: Precose, Glucobay, Prandase, Acarbosum, BAY g 5421\(...TRUNCATED) |
acetate | Acetate for Health & Longevity | https://evipedia.ai/acetate | Acetate | compound | [
"Acetic Acid",
"Acetate Anion",
"Ethanoate",
"Sodium Acetate",
"SCFA Acetate"
] | 2026-06-20T00:00:00 | 2026-06-20T00:00:00 | 2026-06-20T00:00:00 | "Acetate is the most common of the short-chain fats that gut bacteria make from fiber, and it is als(...TRUNCATED) | [{"name":"Health Benefits and Side Effects of Short-Chain Fatty Acids","url":"https://pubmed.ncbi.nl(...TRUNCATED) | "---\ncanonical_name: Acetate\nalternate_names: Acetic Acid, Acetate Anion, Ethanoate, Sodium Acetat(...TRUNCATED) |
acetyl_hexapeptide_8_skin | Acetyl Hexapeptide-8 for Skin Rejuvenation | https://evipedia.ai/acetyl_hexapeptide_8_skin | Acetyl Hexapeptide-8 | skin_compound | [
"Acetyl Hexapeptide-3",
"Argireline",
"AH-8",
"AH-3",
"Acetyl Glutamyl Heptapeptide-1",
"Ac-EEMQRR-NH2"
] | 2026-06-26T00:00:00 | 2026-06-26T00:00:00 | 2026-06-26T00:00:00 | "Acetyl hexapeptide-8, marketed as Argireline, is a small lab-made chain of amino acids sold in crea(...TRUNCATED) | [{"name":"Acetyl Hexapeptide-8 in Cosmeceuticals — A Review of Skin Permeability and Efficacy","ur(...TRUNCATED) | "---\ncanonical_name: Acetyl Hexapeptide-8\nalternate_names: Acetyl Hexapeptide-3, Argireline, AH-8,(...TRUNCATED) |
acetyl_tetrapeptide_2_skin | Acetyl Tetrapeptide-2 for Skin Rejuvenation | https://evipedia.ai/acetyl_tetrapeptide_2_skin | Acetyl Tetrapeptide-2 | skin_compound | [
"Thymulen-4",
"Peptigravity",
"Ac-KDVY",
"Acetyl-Lys-Asp-Val-Tyr"
] | 2026-06-23T00:00:00 | 2026-06-23T00:00:00 | 2026-06-23T00:00:00 | "Acetyl Tetrapeptide-2 is a lab-made four-part peptide, applied to the skin and modeled on a youth-a(...TRUNCATED) | [{"name":"PMID 41924746","url":"https://pubmed.ncbi.nlm.nih.gov/41924746/","pmid":"41924746"},{"name(...TRUNCATED) | "---\ncanonical_name: Acetyl Tetrapeptide-2\nalternate_names: Thymulen-4, Peptigravity, Ac-KDVY, Ace(...TRUNCATED) |
End of preview. Expand in Data Studio
Evipedia Evidence Reviews
The full public catalogue of evipedia.ai — a continuously-updated encyclopedia of evidence reviews on health & longevity interventions — as one record per review. Each record carries the review's metadata plus its complete Markdown body.
- Homepage / source: https://evipedia.ai
- Live file: https://evipedia.ai/evipedia-corpus.jsonl (this dataset mirrors it)
- Publisher: Forever Healthy
- License: CC BY 4.0
What's inside
One JSON object per line (JSON Lines). One line per live review.
| Field | Type | Description |
|---|---|---|
slug |
string | Short id / last path segment of the permalink (e.g. rapamycin). |
topic |
string | Review title (e.g. "Rapamycin for Health & Longevity"). |
url |
string | Canonical review URL on evipedia.ai. |
canonical_name |
string | Intervention name (e.g. "Rapamycin"). |
category |
string | Evipedia category (e.g. medication, compound, diet). |
alternate_names |
string[] | Synonyms / brand names. |
datePublished / dateModified / lastReviewed |
string (ISO date) | Review dates. |
conclusion |
string | Plain-text conclusion of the review. |
citation |
object[] | Primary-source references — {name, url, pmid?} (PMID for PubMed sources). |
markdown |
string | The complete evidence review as Markdown (the review body). |
How it's produced
Generated at site build time from the live evidence reviews and served at
/evipedia-corpus.jsonl; this dataset mirrors that file. It contains only the
public catalogue (the same reviews listed on the site, in /reviews.json, and in
the search index).
Uses
Retrieval-augmented generation, semantic search over health-intervention evidence, summarization, and fine-tuning / evaluation on evidence-grounded medical text. Every record links back to its canonical review and its primary sources.
Updates
The source reviews are refreshed on average every 4–6 weeks; this dataset is re-synced from the live file (see the repo's refresh job).
Attribution
Reuse freely under CC BY 4.0, including for AI training and generation, provided
you credit evipedia.ai and, where practical, link back to the review's
permalink (the url field).
Limitations
Evipedia's reviews are AI-generated and audited; see the limitations & disclaimer. This is educational evidence synthesis, not medical advice.
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