gomesgroup/prism-reactor

PRISM Reactor - 3D Printing Files

📄 [Paper] | 💻 Code

This repository contains all 3D printing files, CAD designs, and G-code files needed to fabricate the PRISM reactor system for automated chemical reaction monitoring and kinetic analysis.

Overview

The PRISM reactor is a custom-built 96-well plate reaction monitoring system designed for high-throughput kinetic studies of amide formation reactions. The system integrates camera-based monitoring, controlled lighting, and automated data collection capabilities.

Repository Structure

The repository contains a single archive file:

3D print files for reactor.tar (~175 MB)

Contains all files needed to 3D print and assemble the PRISM reactor system, organized into three main directories:

1. Solidworks Parts/ (Source CAD Files)

Original Solidworks part files (.SLDPRT) for all reactor components:

• CameraMountBottom.SLDPRT - Bottom camera mount component
• CameraMountTop.SLDPRT - Top camera mount component
• Legs.SLDPRT - Support legs for the reactor
• LightCap.SLDPRT - Light cap assembly
• LightCurtain.SLDPRT - Light curtain component
• LightFilter & Funnel.SLDPRT - Light filter and funnel assembly
• ReactorLid.SLDPRT - Main reactor lid
• v1-96wellplate.SLDPRT - Original 96-well plate design
• v2-96wellLightGradient.SLDPRT - Version 2 with light gradient features

2. STL Files/ (Ready-to-Print)

STL files exported from Solidworks, ready for 3D printing:

• LightCap.STL - Light cap
• ReactorLid.STL - Main reactor lid (also available as "LaprasLid")
• v1-96wellplate.STL - Original 96-well plate
• v1.2-Legs.STL - Support legs (version 1.2)
• v2-96wellLightGradient.STL - Version 2 96-well plate with light gradient
• v2-CameraMountBottom.STL - Camera mount bottom (version 2)
• v2-LightCurtain.STL - Light curtain (version 2)
• v2.1CameraMountTop.STL - Camera mount top (version 2.1)
• v3LightFilter & Funnel.STL - Light filter and funnel (version 3)

3. gcode files (for full reactor printing)/ (Pre-sliced G-code)

Ready-to-print G-code files for direct use with 3D printers:

• 2legs,camTop,camBottom.gcode - Combined print for legs, camera top, and camera bottom
• 96wellPlate and Light Funnel.gcode - Combined print for 96-well plate and light funnel
• LaprasLid.gcode - Reactor lid G-code

Component Descriptions

Main Components

1. 96-Well Plate (v1 and v2)

   • Standard 96-well format for parallel reaction screening
   • Version 2 includes light gradient features for enhanced imaging

2. Reactor Lid (LaprasLid)

   • Main sealing lid for the reactor system
   • Designed to interface with camera and lighting systems

3. Camera Mount (Top and Bottom)

   • Mounting system for camera positioning
   • Version 2.1 top mount with improved design

4. Lighting System

   • Light Cap: Top lighting assembly
   • Light Curtain: Side lighting component
   • Light Filter & Funnel: Light filtering and distribution system (v3)

5. Support Structure

   • Legs: Support legs for reactor stability (v1.2)

Usage

Extracting Files

# Extract the archive
tar -xzf "3D print files for reactor.tar"

3D Printing Options

Option 1: Use Pre-sliced G-code Files

1. Extract the archive
2. Navigate to gcode files (for full reactor printing)/
3. Load the appropriate G-code file directly into your 3D printer
4. Print according to your printer's specifications

Option 2: Use STL Files (Recommended)

1. Extract the archive
2. Navigate to STL Files/
3. Import the STL files into your preferred slicing software (Cura, PrusaSlicer, etc.)
4. Adjust print settings as needed for your printer and material
5. Generate G-code and print

Option 3: Modify CAD Files

1. Extract the archive
2. Open Solidworks part files in Solidworks
3. Modify designs as needed
4. Export to STL format
5. Slice and print

Printing Recommendations

Material

• Recommended: PLA for general use

Print Settings

• Layer Height: 0.2 mm (depending on required resolution)
• Infill: 20-30% gyroid recommended
• Supports: Required for overhanging features (camera mounts, light funnel)
• Bed Temperature: According to filament specifications
• Print Temperature: According to filament specifications

Post-Processing

• Remove support material carefully
• Sand surfaces that need to interface with other components
• Consider chemical-resistant coatings for parts in contact with reagents

Version History

• v1: Original 96-well plate design
• v1.2: Updated leg design
• v2: 96-well plate with light gradient features, updated camera mounts and light curtain
• v2.1: Refined camera mount top
• v3: Updated light filter and funnel design

Assembly Notes

1. Print all required components according to the version you're using
2. Ensure proper fit between components (may require minor sanding/fitting)
3. Assemble camera mount system
4. Install lighting components
5. Attach legs for stability
6. Test fit with 96-well plate before use

Integration with PRISM System

This reactor is designed to work with:

• Camera systems for time-series image capture
• Lighting systems (white and yellow light) for reaction monitoring
• Automated data collection and analysis pipelines
• See the associated Amide Formation Kinetics Dataset for experimental data collected using this reactor

File Formats

• .SLDPRT: Solidworks part files (requires Solidworks to open)
• .STL: Standard 3D printing format (compatible with all slicers)
• .gcode: Pre-sliced G-code files (printer-specific, may need adjustment)

Compatibility

The G-code files are provided as-is and may require adjustment for:

• Different 3D printer models
• Different nozzle sizes
• Different bed sizes
• Different material properties They are set for a bed temp of 60 C and a nozzle temp of 205 C. Speed can be adjusted on the fly on most printers.

It is recommended to use the STL files with your own slicing settings for best results.

Citation

If you use this reactor design in your research, please cite:

@dataset{PRISM_reactor_2025,
  title={PRISM Reactor - 3D Printing Files},
  author={Baumer, Mitchell and Kubaney, Andrew and Bernhard, Stefan},
  year={2025},
  institution={Carnegie Mellon University},
  publisher={Hugging Face},
  url={[gomesgroup/prism-reactor]}
}

License

Copyright 2025 Bernhard Group (Mitchell Baumer, Andrew Kubaney, Stefan Bernhard), Carnegie Mellon University

This work is licensed under the Apache License 2.0 with Commons Clause License Condition v1.0.

Commons Clause Condition: The grant of rights under the License does not include, and the License does not grant to you, the right to Sell the Software. "Sell" means practicing any or all of the rights granted to you under the License to provide to third parties, for a fee or other consideration (including without limitation fees for hosting or consulting/support services related to the Software), a product or service whose value derives, entirely or substantially, from the functionality of the Software.

Full License: Apache License, Version 2.0

See the LICENSE file for the full license text.

Contact

For questions or issues regarding the reactor design, please contact mbaumer@andrew.cmu.edu.

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Note: This repository contains design files for a custom reactor system. Users should verify compatibility with their specific 3D printer and adjust settings accordingly. The designs are provided as-is for research and educational purposes.