sentence1
stringlengths
52
3.87M
sentence2
stringlengths
1
47.2k
label
stringclasses
1 value
def full_data(self): """ Returns all the info available for the user in the following format: name [username] <id> (locale) bot_or_user If any data is not available, it is not added. """ data = [ self.full_name, self._username(), se...
Returns all the info available for the user in the following format: name [username] <id> (locale) bot_or_user If any data is not available, it is not added.
entailment
def full_data(self): """ Returns all the info available for the chat in the following format: title [username] (type) <id> If any data is not available, it is not added. """ data = [ self.chat.title, self._username(), self._type(), ...
Returns all the info available for the chat in the following format: title [username] (type) <id> If any data is not available, it is not added.
entailment
def use_defaults(func): """ Decorator for functions that should automatically fall back to the Cohort-default filter_fn and normalized_per_mb if not specified. """ @wraps(func) def wrapper(row, cohort, filter_fn=None, normalized_per_mb=None, **kwargs): filter_fn = first_not_none_param([f...
Decorator for functions that should automatically fall back to the Cohort-default filter_fn and normalized_per_mb if not specified.
entailment
def count_function(func): """ Decorator for functions that return a collection (technically a dict of collections) that should be counted up. Also automatically falls back to the Cohort-default filter_fn and normalized_per_mb if not specified. """ # Fall back to Cohort-level defaults. @use_d...
Decorator for functions that return a collection (technically a dict of collections) that should be counted up. Also automatically falls back to the Cohort-default filter_fn and normalized_per_mb if not specified.
entailment
def count_variants_function_builder(function_name, filterable_variant_function=None): """ Creates a function that counts variants that are filtered by the provided filterable_variant_function. The filterable_variant_function is a function that takes a filterable_variant and returns True or False. Users...
Creates a function that counts variants that are filtered by the provided filterable_variant_function. The filterable_variant_function is a function that takes a filterable_variant and returns True or False. Users of this builder need not worry about applying e.g. the Cohort's default `filter_fn`. That will be...
entailment
def count_effects_function_builder(function_name, only_nonsynonymous, filterable_effect_function=None): """ Create a function that counts effects that are filtered by the provided filterable_effect_function. The filterable_effect_function is a function that takes a filterable_effect and returns True or Fals...
Create a function that counts effects that are filtered by the provided filterable_effect_function. The filterable_effect_function is a function that takes a filterable_effect and returns True or False. Users of this builder need not worry about applying e.g. the Cohort's default `filter_fn`. That will be appl...
entailment
def median_vaf_purity(row, cohort, **kwargs): """ Estimate purity based on 2 * median VAF. Even if the Cohort has a default filter_fn, ignore it: we want to use all variants for this estimate. """ patient_id = row["patient_id"] patient = cohort.patient_from_id(patient_id) variants = coh...
Estimate purity based on 2 * median VAF. Even if the Cohort has a default filter_fn, ignore it: we want to use all variants for this estimate.
entailment
def bootstrap_auc(df, col, pred_col, n_bootstrap=1000): """ Calculate the boostrapped AUC for a given col trying to predict a pred_col. Parameters ---------- df : pandas.DataFrame col : str column to retrieve the values from pred_col : str the column we're trying to predict ...
Calculate the boostrapped AUC for a given col trying to predict a pred_col. Parameters ---------- df : pandas.DataFrame col : str column to retrieve the values from pred_col : str the column we're trying to predict n_boostrap : int the number of bootstrap samples Re...
entailment
def set_callbacks(self, worker_start_callback: callable, worker_end_callback: callable, are_async: bool = False): """ :param are_async: True if the callbacks execute asynchronously, posting any heavy work to another thread. """ # We are setting self.worker_start_callback and self.worker_...
:param are_async: True if the callbacks execute asynchronously, posting any heavy work to another thread.
entailment
def _start_worker(self, worker: Worker): """ Can be safely called multiple times on the same worker (for workers that support it) to start a new thread for it. """ # This function is called from main thread and from worker pools threads to start their children threads wit...
Can be safely called multiple times on the same worker (for workers that support it) to start a new thread for it.
entailment
def new_worker(self, name: str): """Creates a new Worker and start a new Thread with it. Returns the Worker.""" if not self.running: return self.immediate_worker worker = self._new_worker(name) self._start_worker(worker) return worker
Creates a new Worker and start a new Thread with it. Returns the Worker.
entailment
def new_worker_pool(self, name: str, min_workers: int = 0, max_workers: int = 1, max_seconds_idle: int = DEFAULT_WORKER_POOL_MAX_SECONDS_IDLE): """ Creates a new worker pool and starts it. Returns the Worker that schedules works to the pool. """ if not sel...
Creates a new worker pool and starts it. Returns the Worker that schedules works to the pool.
entailment
def as_dataframe(self, on=None, join_with=None, join_how=None, return_cols=False, rename_cols=False, keep_paren_contents=True, **kwargs): """ Return this Cohort as a DataFrame, and optionally include additional columns using `on`. on : str or fu...
Return this Cohort as a DataFrame, and optionally include additional columns using `on`. on : str or function or list or dict, optional - A column name. - Or a function that creates a new column for comparison, e.g. count.snv_count. - Or a list of column-generating f...
entailment
def load_dataframe(self, df_loader_name): """ Instead of joining a DataFrameJoiner with the Cohort in `as_dataframe`, sometimes we may want to just directly load a particular DataFrame. """ logger.debug("loading dataframe: {}".format(df_loader_name)) # Get the DataFrameLo...
Instead of joining a DataFrameJoiner with the Cohort in `as_dataframe`, sometimes we may want to just directly load a particular DataFrame.
entailment
def _get_function_name(self, fn, default="None"): """ Return name of function, using default value if function not defined """ if fn is None: fn_name = default else: fn_name = fn.__name__ return fn_name
Return name of function, using default value if function not defined
entailment
def load_variants(self, patients=None, filter_fn=None, **kwargs): """Load a dictionary of patient_id to varcode.VariantCollection Parameters ---------- patients : str, optional Filter to a subset of patients filter_fn : function Takes a FilterableVariant ...
Load a dictionary of patient_id to varcode.VariantCollection Parameters ---------- patients : str, optional Filter to a subset of patients filter_fn : function Takes a FilterableVariant and returns a boolean. Only variants returning True are preserved. ...
entailment
def _hash_filter_fn(self, filter_fn, **kwargs): """ Construct string representing state of filter_fn Used to cache filtered variants or effects uniquely depending on filter fn values """ filter_fn_name = self._get_function_name(filter_fn, default="filter-none") logger.debug("...
Construct string representing state of filter_fn Used to cache filtered variants or effects uniquely depending on filter fn values
entailment
def _load_single_patient_variants(self, patient, filter_fn, use_cache=True, **kwargs): """ Load filtered, merged variants for a single patient, optionally using cache Note that filtered variants are first merged before filtering, and each step is cached independently. Turn on debug ...
Load filtered, merged variants for a single patient, optionally using cache Note that filtered variants are first merged before filtering, and each step is cached independently. Turn on debug statements for more details about cached files. Use `_load_single_pati...
entailment
def _load_single_patient_merged_variants(self, patient, use_cache=True): """ Load merged variants for a single patient, optionally using cache Note that merged variants are not filtered. Use `_load_single_patient_variants` to get filtered variants """ logger.debug("loadi...
Load merged variants for a single patient, optionally using cache Note that merged variants are not filtered. Use `_load_single_patient_variants` to get filtered variants
entailment
def load_polyphen_annotations(self, as_dataframe=False, filter_fn=None): """Load a dataframe containing polyphen2 annotations for all variants Parameters ---------- database_file : string, sqlite Path to the WHESS/Polyphen2 SQLite database. ...
Load a dataframe containing polyphen2 annotations for all variants Parameters ---------- database_file : string, sqlite Path to the WHESS/Polyphen2 SQLite database. Can be downloaded and bunzip2"ed from http://bit.ly/208mlIU filter_fn : function Takes...
entailment
def load_effects(self, patients=None, only_nonsynonymous=False, all_effects=False, filter_fn=None, **kwargs): """Load a dictionary of patient_id to varcode.EffectCollection Note that this only loads one effect per variant. Parameters ---------- patients : s...
Load a dictionary of patient_id to varcode.EffectCollection Note that this only loads one effect per variant. Parameters ---------- patients : str, optional Filter to a subset of patients only_nonsynonymous : bool, optional If true, load only nonsynonymo...
entailment
def load_kallisto(self): """ Load Kallisto transcript quantification data for a cohort Parameters ---------- Returns ------- kallisto_data : Pandas dataframe Pandas dataframe with Kallisto data for all patients columns include patient_id,...
Load Kallisto transcript quantification data for a cohort Parameters ---------- Returns ------- kallisto_data : Pandas dataframe Pandas dataframe with Kallisto data for all patients columns include patient_id, gene_name, est_counts
entailment
def _load_single_patient_kallisto(self, patient): """ Load Kallisto gene quantification given a patient Parameters ---------- patient : Patient Returns ------- data: Pandas dataframe Pandas dataframe of sample's Kallisto data colu...
Load Kallisto gene quantification given a patient Parameters ---------- patient : Patient Returns ------- data: Pandas dataframe Pandas dataframe of sample's Kallisto data columns include patient_id, target_id, length, eff_length, est_counts, tpm
entailment
def load_cufflinks(self, filter_ok=True): """ Load a Cufflinks gene expression data for a cohort Parameters ---------- filter_ok : bool, optional If true, filter Cufflinks data to row with FPKM_status == "OK" Returns ------- cufflinks_data : ...
Load a Cufflinks gene expression data for a cohort Parameters ---------- filter_ok : bool, optional If true, filter Cufflinks data to row with FPKM_status == "OK" Returns ------- cufflinks_data : Pandas dataframe Pandas dataframe with Cufflinks d...
entailment
def _load_single_patient_cufflinks(self, patient, filter_ok): """ Load Cufflinks gene quantification given a patient Parameters ---------- patient : Patient filter_ok : bool, optional If true, filter Cufflinks data to row with FPKM_status == "OK" Ret...
Load Cufflinks gene quantification given a patient Parameters ---------- patient : Patient filter_ok : bool, optional If true, filter Cufflinks data to row with FPKM_status == "OK" Returns ------- data: Pandas dataframe Pandas dataframe o...
entailment
def get_filtered_isovar_epitopes(self, epitopes, ic50_cutoff): """ Mostly replicates topiary.build_epitope_collection_from_binding_predictions Note: topiary needs to do fancy stuff like subsequence_protein_offset + binding_prediction.offset in order to figure out whether a variant is in...
Mostly replicates topiary.build_epitope_collection_from_binding_predictions Note: topiary needs to do fancy stuff like subsequence_protein_offset + binding_prediction.offset in order to figure out whether a variant is in the peptide because it only has the variant's offset into the full protein...
entailment
def plot_roc_curve(self, on, bootstrap_samples=100, ax=None, **kwargs): """Plot an ROC curve for benefit and a given variable Parameters ---------- on : str or function or list or dict See `cohort.load.as_dataframe` bootstrap_samples : int, optional Numbe...
Plot an ROC curve for benefit and a given variable Parameters ---------- on : str or function or list or dict See `cohort.load.as_dataframe` bootstrap_samples : int, optional Number of boostrap samples to use to compute the AUC ax : Axes, default None ...
entailment
def plot_benefit(self, on, benefit_col="benefit", label="Response", ax=None, alternative="two-sided", boolean_value_map={}, order=None, **kwargs): """Plot a comparison of benefit/response in the cohort on a given variable """ no_benefit_plot_name = "No %...
Plot a comparison of benefit/response in the cohort on a given variable
entailment
def plot_boolean(self, on, boolean_col, plot_col=None, boolean_label=None, boolean_value_map={}, order=None, ax=None, alternative="two-sided", ...
Plot a comparison of `boolean_col` in the cohort on a given variable via `on` or `col`. If the variable (through `on` or `col`) is binary this will compare odds-ratios and perform a Fisher's exact test. If the variable is numeric, this will compare the distributions through a M...
entailment
def plot_survival(self, on, how="os", survival_units="Days", strata=None, ax=None, ci_show=False, with_condition_color="#B38600", no_condition_c...
Plot a Kaplan Meier survival curve by splitting the cohort into two groups Parameters ---------- on : str or function or list or dict See `cohort.load.as_dataframe` how : {"os", "pfs"}, optional Whether to plot OS (overall survival) or PFS (progression free surviv...
entailment
def plot_correlation(self, on, x_col=None, plot_type="jointplot", stat_func=pearsonr, show_stat_func=True, plot_kwargs={}, **kwargs): """Plot the correlation between two variables. Parameters ---------- on : list or dict of functions or strings See `cohort.load.as_dataframe`...
Plot the correlation between two variables. Parameters ---------- on : list or dict of functions or strings See `cohort.load.as_dataframe` x_col : str, optional If `on` is a dict, this guarantees we have the expected ordering. plot_type : str, optional ...
entailment
def _list_patient_ids(self): """ Utility function to return a list of patient ids in the Cohort """ results = [] for patient in self: results.append(patient.id) return(results)
Utility function to return a list of patient ids in the Cohort
entailment
def summarize_provenance_per_cache(self): """Utility function to summarize provenance files for cached items used by a Cohort, for each cache_dir that exists. Only existing cache_dirs are summarized. This is a summary of provenance files because the function checks to see whether all pa...
Utility function to summarize provenance files for cached items used by a Cohort, for each cache_dir that exists. Only existing cache_dirs are summarized. This is a summary of provenance files because the function checks to see whether all patients data have the same provenance within the cache...
entailment
def summarize_dataframe(self): """Summarize default dataframe for this cohort using a hash function. Useful for confirming the version of data used in various reports, e.g. ipynbs """ if self.dataframe_hash: return(self.dataframe_hash) else: df = self._as_...
Summarize default dataframe for this cohort using a hash function. Useful for confirming the version of data used in various reports, e.g. ipynbs
entailment
def summarize_provenance(self): """Utility function to summarize provenance files for cached items used by a Cohort. At the moment, most PROVENANCE files contain details about packages used to generate files. However, this function is generic & so it summarizes the contents of those fil...
Utility function to summarize provenance files for cached items used by a Cohort. At the moment, most PROVENANCE files contain details about packages used to generate files. However, this function is generic & so it summarizes the contents of those files irrespective of their contents. ...
entailment
def summarize_data_sources(self): """Utility function to summarize data source status for this Cohort, useful for confirming the state of data used for an analysis Returns ---------- Dictionary with summary of data sources Currently contains - dataframe_hash: ha...
Utility function to summarize data source status for this Cohort, useful for confirming the state of data used for an analysis Returns ---------- Dictionary with summary of data sources Currently contains - dataframe_hash: hash of the dataframe (see `?cohorts.Cohort.sum...
entailment
def strelka_somatic_variant_stats(variant, variant_metadata): """Parse out the variant calling statistics for a given variant from a Strelka VCF Parameters ---------- variant : varcode.Variant sample_info : dict Dictionary of sample to variant calling statistics, corresponds to the sample c...
Parse out the variant calling statistics for a given variant from a Strelka VCF Parameters ---------- variant : varcode.Variant sample_info : dict Dictionary of sample to variant calling statistics, corresponds to the sample columns in a Strelka VCF Returns ------- SomaticV...
entailment
def _strelka_variant_stats(variant, sample_info): """Parse a single sample"s variant calling statistics based on Strelka VCF output Parameters ---------- variant : varcode.Variant sample_info : dict Dictionary of Strelka-specific variant calling fields Returns ------- VariantSt...
Parse a single sample"s variant calling statistics based on Strelka VCF output Parameters ---------- variant : varcode.Variant sample_info : dict Dictionary of Strelka-specific variant calling fields Returns ------- VariantStats
entailment
def mutect_somatic_variant_stats(variant, variant_metadata): """Parse out the variant calling statistics for a given variant from a Mutect VCF Parameters ---------- variant : varcode.Variant sample_info : dict Dictionary of sample to variant calling statistics, corresponds to the sample col...
Parse out the variant calling statistics for a given variant from a Mutect VCF Parameters ---------- variant : varcode.Variant sample_info : dict Dictionary of sample to variant calling statistics, corresponds to the sample columns in a Mutect VCF Returns ------- SomaticVar...
entailment
def _mutect_variant_stats(variant, sample_info): """Parse a single sample"s variant calling statistics based on Mutect"s (v1) VCF output Parameters ---------- variant : varcode.Variant sample_info : dict Dictionary of Mutect-specific variant calling fields Returns ------- Varia...
Parse a single sample"s variant calling statistics based on Mutect"s (v1) VCF output Parameters ---------- variant : varcode.Variant sample_info : dict Dictionary of Mutect-specific variant calling fields Returns ------- VariantStats
entailment
def maf_somatic_variant_stats(variant, variant_metadata): """ Parse out the variant calling statistics for a given variant from a MAF file Assumes the MAF format described here: https://www.biostars.org/p/161298/#161777 Parameters ---------- variant : varcode.Variant variant_metadata : dic...
Parse out the variant calling statistics for a given variant from a MAF file Assumes the MAF format described here: https://www.biostars.org/p/161298/#161777 Parameters ---------- variant : varcode.Variant variant_metadata : dict Dictionary of metadata for this variant Returns ---...
entailment
def _vcf_is_strelka(variant_file, variant_metadata): """Return True if variant_file given is in strelka format """ if "strelka" in variant_file.lower(): return True elif "NORMAL" in variant_metadata["sample_info"].keys(): return True else: vcf_reader = vcf.Reader(open(variant...
Return True if variant_file given is in strelka format
entailment
def variant_stats_from_variant(variant, metadata, merge_fn=(lambda all_stats: \ max(all_stats, key=(lambda stats: stats.tumor_stats.depth)))): """Parse the variant calling stats from a variant called from multiple variant ...
Parse the variant calling stats from a variant called from multiple variant files. The stats are merged based on `merge_fn` Parameters ---------- variant : varcode.Variant metadata : dict Dictionary of variant file to variant calling metadata from that file merge_fn : function F...
entailment
def _get_and_execute(self): """ :return: True if it should continue running, False if it should end its execution. """ try: work = self.queue.get(timeout=self.max_seconds_idle) except queue.Empty: # max_seconds_idle has been exhausted, exiting ...
:return: True if it should continue running, False if it should end its execution.
entailment
def format(self, full_info: bool = False): """ :param full_info: If True, adds more info about the chat. Please, note that this additional info requires to make up to THREE synchronous api calls. """ chat = self.api_object if full_info: self.__format_full(...
:param full_info: If True, adds more info about the chat. Please, note that this additional info requires to make up to THREE synchronous api calls.
entailment
def list(self): """ :rtype: list(setting_name, value, default_value, is_set, is_supported) """ settings = [] for setting in _SETTINGS: value = self.get(setting) is_set = self.is_set(setting) default_value = self.get_default_value(setting) ...
:rtype: list(setting_name, value, default_value, is_set, is_supported)
entailment
def load_ensembl_coverage(cohort, coverage_path, min_tumor_depth, min_normal_depth=0, pageant_dir_fn=None): """ Load in Pageant CoverageDepth results with Ensembl loci. coverage_path is a path to Pageant CoverageDepth output directory, with one subdirectory per patient and a `...
Load in Pageant CoverageDepth results with Ensembl loci. coverage_path is a path to Pageant CoverageDepth output directory, with one subdirectory per patient and a `cdf.csv` file inside each patient subdir. If min_normal_depth is 0, calculate tumor coverage. Otherwise, calculate join tumor/normal cove...
entailment
def vertical_percent(plot, percent=0.1): """ Using the size of the y axis, return a fraction of that size. """ plot_bottom, plot_top = plot.get_ylim() return percent * (plot_top - plot_bottom)
Using the size of the y axis, return a fraction of that size.
entailment
def hide_ticks(plot, min_tick_value=None, max_tick_value=None): """Hide tick values that are outside of [min_tick_value, max_tick_value]""" for tick, tick_value in zip(plot.get_yticklabels(), plot.get_yticks()): tick_label = as_numeric(tick_value) if tick_label: if (min_tick_value is...
Hide tick values that are outside of [min_tick_value, max_tick_value]
entailment
def add_significance_indicator(plot, col_a=0, col_b=1, significant=False): """ Add a p-value significance indicator. """ plot_bottom, plot_top = plot.get_ylim() # Give the plot a little room for the significance indicator line_height = vertical_percent(plot, 0.1) # Add some extra spacing bel...
Add a p-value significance indicator.
entailment
def stripboxplot(x, y, data, ax=None, significant=None, **kwargs): """ Overlay a stripplot on top of a boxplot. """ ax = sb.boxplot( x=x, y=y, data=data, ax=ax, fliersize=0, **kwargs ) plot = sb.stripplot( x=x, y=y, data=da...
Overlay a stripplot on top of a boxplot.
entailment
def fishers_exact_plot(data, condition1, condition2, ax=None, condition1_value=None, alternative="two-sided", **kwargs): """ Perform a Fisher's exact test to compare to binary columns Parameters ---------- data: Pandas dataframe Dataframe to ret...
Perform a Fisher's exact test to compare to binary columns Parameters ---------- data: Pandas dataframe Dataframe to retrieve information from condition1: str First binary column to compare (and used for test sidedness) condition2: str Second binary column to compare ...
entailment
def mann_whitney_plot(data, condition, distribution, ax=None, condition_value=None, alternative="two-sided", skip_plot=False, **kwargs): """ Create a box plot...
Create a box plot comparing a condition and perform a Mann Whitney test to compare the distribution in condition A v B Parameters ---------- data: Pandas dataframe Dataframe to retrieve information from condition: str Column to use as the splitting criteria distribution: str ...
entailment
def roc_curve_plot(data, value_column, outcome_column, bootstrap_samples=100, ax=None): """Create a ROC curve and compute the bootstrap AUC for the given variable and outcome Parameters ---------- data : Pandas dataframe Dataframe to retrieve information from value_column : str Colu...
Create a ROC curve and compute the bootstrap AUC for the given variable and outcome Parameters ---------- data : Pandas dataframe Dataframe to retrieve information from value_column : str Column to retrieve the values from outcome_column : str Column to use as the outcome va...
entailment
def get_cache_dir(cache_dir, cache_root_dir=None, *args, **kwargs): """ Return full cache_dir, according to following logic: - if cache_dir is a full path (per path.isabs), return that value - if not and if cache_root_dir is not None, join two paths - otherwise, log warnings and return N...
Return full cache_dir, according to following logic: - if cache_dir is a full path (per path.isabs), return that value - if not and if cache_root_dir is not None, join two paths - otherwise, log warnings and return None Separately, if args or kwargs are given, format cache_dir using kwargs
entailment
def _strip_column_name(col_name, keep_paren_contents=True): """ Utility script applying several regexs to a string. Intended to be used by `strip_column_names`. This function will: 1. replace informative punctuation components with text 2. (optionally) remove text within parentheses ...
Utility script applying several regexs to a string. Intended to be used by `strip_column_names`. This function will: 1. replace informative punctuation components with text 2. (optionally) remove text within parentheses 3. replace remaining punctuation/whitespace with _ 4. strip...
entailment
def strip_column_names(cols, keep_paren_contents=True): """ Utility script for renaming pandas columns to patsy-friendly names. Revised names have been: - stripped of all punctuation and whitespace (converted to text or `_`) - converted to lower case Takes a list of column names, retur...
Utility script for renaming pandas columns to patsy-friendly names. Revised names have been: - stripped of all punctuation and whitespace (converted to text or `_`) - converted to lower case Takes a list of column names, returns a dict mapping names to revised names. If there are any ...
entailment
def set_attributes(obj, additional_data): """ Given an object and a dictionary, give the object new attributes from that dictionary. Uses _strip_column_name to git rid of whitespace/uppercase/special characters. """ for key, value in additional_data.items(): if hasattr(obj, key): ...
Given an object and a dictionary, give the object new attributes from that dictionary. Uses _strip_column_name to git rid of whitespace/uppercase/special characters.
entailment
def return_obj(cols, df, return_cols=False): """Construct a DataFrameHolder and then return either that or the DataFrame.""" df_holder = DataFrameHolder(cols=cols, df=df) return df_holder.return_self(return_cols=return_cols)
Construct a DataFrameHolder and then return either that or the DataFrame.
entailment
def compare_provenance( this_provenance, other_provenance, left_outer_diff = "In current but not comparison", right_outer_diff = "In comparison but not current"): """Utility function to compare two abritrary provenance dicts returns number of discrepancies. Parameters ----------...
Utility function to compare two abritrary provenance dicts returns number of discrepancies. Parameters ---------- this_provenance: provenance dict (to be compared to "other_provenance") other_provenance: comparison provenance dict (optional) left_outer_diff: description/prefix used when pr...
entailment
def _plot_kmf_single(df, condition_col, survival_col, censor_col, threshold, title, xlabel, ylabel, ax, with_condition_color, ...
Helper function to produce a single KM survival plot, among observations in df by groups defined by condition_col. All inputs are required - this function is intended to be called by `plot_kmf`.
entailment
def plot_kmf(df, condition_col, censor_col, survival_col, strata_col=None, threshold=None, title=None, xlabel=None, ylabel=None, ax=None, with_condition_color="#B38600", no_cond...
Plot survival curves by splitting the dataset into two groups based on condition_col. Report results for a log-rank test (if two groups are plotted) or CoxPH survival analysis (if >2 groups) for association with survival. Regarding definition of groups: If condition_col is numeric, values are split...
entailment
def concat(self, formatted_text): """:type formatted_text: FormattedText""" assert self._is_compatible(formatted_text), "Cannot concat text with different modes" self.text += formatted_text.text return self
:type formatted_text: FormattedText
entailment
def join(self, formatted_texts): """:type formatted_texts: list[FormattedText]""" formatted_texts = list(formatted_texts) # so that after the first iteration elements are not lost if generator for formatted_text in formatted_texts: assert self._is_compatible(formatted_text), "Cannot...
:type formatted_texts: list[FormattedText]
entailment
def concat(self, *args, **kwargs): """ :type args: FormattedText :type kwargs: FormattedText """ for arg in args: assert self.formatted_text._is_compatible(arg), "Cannot concat text with different modes" self.format_args.append(arg.text) for kwarg ...
:type args: FormattedText :type kwargs: FormattedText
entailment
def random_cohort(size, cache_dir, data_dir=None, min_random_variants=None, max_random_variants=None, seed_val=1234): """ Parameters ---------- min_random_variants: optional, int Minimum number of random variants to be generated per patient. ...
Parameters ---------- min_random_variants: optional, int Minimum number of random variants to be generated per patient. max_random_variants: optional, int Maximum number of random variants to be generated per patient.
entailment
def generate_random_missense_variants(num_variants=10, max_search=100000, reference="GRCh37"): """ Generate a random collection of missense variants by trying random variants repeatedly. """ variants = [] for i in range(max_search): bases = ["A", "C", "T", "G"] random_ref = choice(ba...
Generate a random collection of missense variants by trying random variants repeatedly.
entailment
def generate_simple_vcf(filename, variant_collection): """ Output a very simple metadata-free VCF for each variant in a variant_collection. """ contigs = [] positions = [] refs = [] alts = [] for variant in variant_collection: contigs.append("chr" + variant.contig) positi...
Output a very simple metadata-free VCF for each variant in a variant_collection.
entailment
def list_folder(self, path): """Looks up folder contents of `path.`""" # Inspired by https://github.com/rspivak/sftpserver/blob/0.3/src/sftpserver/stub_sftp.py#L70 try: folder_contents = [] for f in os.listdir(path): attr = paramiko.SFTPAttributes.from_sta...
Looks up folder contents of `path.`
entailment
def filter_variants(variant_collection, patient, filter_fn, **kwargs): """Filter variants from the Variant Collection Parameters ---------- variant_collection : varcode.VariantCollection patient : cohorts.Patient filter_fn: function Takes a FilterableVariant and returns a boolean. Only ...
Filter variants from the Variant Collection Parameters ---------- variant_collection : varcode.VariantCollection patient : cohorts.Patient filter_fn: function Takes a FilterableVariant and returns a boolean. Only variants returning True are preserved. Returns ------- varcode.Va...
entailment
def filter_effects(effect_collection, variant_collection, patient, filter_fn, all_effects, **kwargs): """Filter variants from the Effect Collection Parameters ---------- effect_collection : varcode.EffectCollection variant_collection : varcode.VariantCollection patient : cohorts.Patient fil...
Filter variants from the Effect Collection Parameters ---------- effect_collection : varcode.EffectCollection variant_collection : varcode.VariantCollection patient : cohorts.Patient filter_fn : function Takes a FilterableEffect and returns a boolean. Only effects returning True are pre...
entailment
def count_lines_in(filename): "Count lines in a file" f = open(filename) lines = 0 buf_size = 1024 * 1024 read_f = f.read # loop optimization buf = read_f(buf_size) while buf: lines += buf.count('\n') buf = read_f(buf_size) return lines
Count lines in a file
entailment
def view_name_from(path): "Resolve a path to the full python module name of the related view function" try: return CACHED_VIEWS[path] except KeyError: view = resolve(path) module = path name = '' if hasattr(view.func, '__module__'): module = resol...
Resolve a path to the full python module name of the related view function
entailment
def generate_table_from(data): "Output a nicely formatted ascii table" table = Texttable(max_width=120) table.add_row(["view", "method", "status", "count", "minimum", "maximum", "mean", "stdev", "queries", "querytime"]) table.set_cols_align(["l", "l", "l", "r", "r", "r", "r", "r", "r", "r"]) for i...
Output a nicely formatted ascii table
entailment
def analyze_log_file(logfile, pattern, reverse_paths=True, progress=True): "Given a log file and regex group and extract the performance data" if progress: lines = count_lines_in(logfile) pbar = ProgressBar(widgets=[Percentage(), Bar()], maxval=lines+1).start() counter = 0 data ...
Given a log file and regex group and extract the performance data
entailment
def to_string(self, limit=None): """ Create a string representation of this collection, showing up to `limit` items. """ header = self.short_string() if len(self) == 0: return header contents = "" element_lines = [ " -- %s" % (elem...
Create a string representation of this collection, showing up to `limit` items.
entailment
def get_instance(cls, state): """:rtype: UserStorageHandler""" if cls.instance is None: cls.instance = UserStorageHandler(state) return cls.instance
:rtype: UserStorageHandler
entailment
def _get_active_threads_names(): """May contain sensitive info (like user ids). Use with care.""" active_threads = threading.enumerate() return FormattedText().join( [ FormattedText().newline().normal(" - {name}").start_format().bold(name=thread.name).end_format() ...
May contain sensitive info (like user ids). Use with care.
entailment
def _get_running_workers_names(running_workers: list): """May contain sensitive info (like user ids). Use with care.""" return FormattedText().join( [ FormattedText().newline().normal(" - {name}").start_format().bold(name=worker.name).end_format() for worker i...
May contain sensitive info (like user ids). Use with care.
entailment
def _get_worker_pools_names(worker_pools: list): """May contain sensitive info (like user ids). Use with care.""" return FormattedText().join( [ FormattedText().newline().normal(" - {name}").start_format().bold(name=worker.name).end_format() for worker in work...
May contain sensitive info (like user ids). Use with care.
entailment
def format(self, member_info: bool = False): """ :param member_info: If True, adds also chat member info. Please, note that this additional info requires to make ONE api call. """ user = self.api_object self.__format_user(user) if member_info and self.chat.typ...
:param member_info: If True, adds also chat member info. Please, note that this additional info requires to make ONE api call.
entailment
def safe_log_error(self, error: Exception, *info: str): """Log error failing silently on error""" self.__do_safe(lambda: self.logger.error(error, *info))
Log error failing silently on error
entailment
def safe_log_info(self, *info: str): """Log info failing silently on error""" self.__do_safe(lambda: self.logger.info(*info))
Log info failing silently on error
entailment
def wald_wolfowitz(sequence): """ implements the wald-wolfowitz runs test: http://en.wikipedia.org/wiki/Wald-Wolfowitz_runs_test http://support.sas.com/kb/33/092.html :param sequence: any iterable with at most 2 values. e.g. '1001001' [1, 0, 1, 0, 1] ...
implements the wald-wolfowitz runs test: http://en.wikipedia.org/wiki/Wald-Wolfowitz_runs_test http://support.sas.com/kb/33/092.html :param sequence: any iterable with at most 2 values. e.g. '1001001' [1, 0, 1, 0, 1] 'abaaabbba' :rtype: a ...
entailment
def auto_correlation(sequence): """ test for the autocorrelation of a sequence between t and t - 1 as the 'auto_correlation' it is less likely that the sequence is generated randomly. :param sequence: any iterable with at most 2 values that can be turned into a float via np.floa...
test for the autocorrelation of a sequence between t and t - 1 as the 'auto_correlation' it is less likely that the sequence is generated randomly. :param sequence: any iterable with at most 2 values that can be turned into a float via np.float . e.g. '1001001' ...
entailment
def _parse_header_links(response): """ Parse the links from a Link: header field. .. todo:: Links with the same relation collide at the moment. :param bytes value: The header value. :rtype: `dict` :return: A dictionary of parsed links, keyed by ``rel`` or ``url``. """ values = respon...
Parse the links from a Link: header field. .. todo:: Links with the same relation collide at the moment. :param bytes value: The header value. :rtype: `dict` :return: A dictionary of parsed links, keyed by ``rel`` or ``url``.
entailment
def _default_client(jws_client, reactor, key, alg): """ Make a client if we didn't get one. """ if jws_client is None: pool = HTTPConnectionPool(reactor) agent = Agent(reactor, pool=pool) jws_client = JWSClient(HTTPClient(agent=agent), key, alg) return jws_client
Make a client if we didn't get one.
entailment
def _find_supported_challenge(authzr, responders): """ Find a challenge combination that consists of a single challenge that the responder can satisfy. :param ~acme.messages.AuthorizationResource auth: The authorization to examine. :type responder: List[`~txacme.interfaces.IResponder`] ...
Find a challenge combination that consists of a single challenge that the responder can satisfy. :param ~acme.messages.AuthorizationResource auth: The authorization to examine. :type responder: List[`~txacme.interfaces.IResponder`] :param responder: The possible responders to use. :raises...
entailment
def answer_challenge(authzr, client, responders): """ Complete an authorization using a responder. :param ~acme.messages.AuthorizationResource auth: The authorization to complete. :param .Client client: The ACME client. :type responders: List[`~txacme.interfaces.IResponder`] :param res...
Complete an authorization using a responder. :param ~acme.messages.AuthorizationResource auth: The authorization to complete. :param .Client client: The ACME client. :type responders: List[`~txacme.interfaces.IResponder`] :param responders: A list of responders that can be used to complete the...
entailment
def poll_until_valid(authzr, clock, client, timeout=300.0): """ Poll an authorization until it is in a state other than pending or processing. :param ~acme.messages.AuthorizationResource auth: The authorization to complete. :param clock: The ``IReactorTime`` implementation to use; usually t...
Poll an authorization until it is in a state other than pending or processing. :param ~acme.messages.AuthorizationResource auth: The authorization to complete. :param clock: The ``IReactorTime`` implementation to use; usually the reactor, when not testing. :param .Client client: The ACM...
entailment
def from_url(cls, reactor, url, key, alg=RS256, jws_client=None): """ Construct a client from an ACME directory at a given URL. :param url: The ``twisted.python.url.URL`` to fetch the directory from. See `txacme.urls` for constants for various well-known public directori...
Construct a client from an ACME directory at a given URL. :param url: The ``twisted.python.url.URL`` to fetch the directory from. See `txacme.urls` for constants for various well-known public directories. :param reactor: The Twisted reactor to use. :param ~josepy.jwk.JWK...
entailment
def register(self, new_reg=None): """ Create a new registration with the ACME server. :param ~acme.messages.NewRegistration new_reg: The registration message to use, or ``None`` to construct one. :return: The registration resource. :rtype: Deferred[`~acme.messages.R...
Create a new registration with the ACME server. :param ~acme.messages.NewRegistration new_reg: The registration message to use, or ``None`` to construct one. :return: The registration resource. :rtype: Deferred[`~acme.messages.RegistrationResource`]
entailment
def _maybe_location(cls, response, uri=None): """ Get the Location: if there is one. """ location = response.headers.getRawHeaders(b'location', [None])[0] if location is not None: return location.decode('ascii') return uri
Get the Location: if there is one.
entailment
def _maybe_registered(self, failure, new_reg): """ If the registration already exists, we should just load it. """ failure.trap(ServerError) response = failure.value.response if response.code == http.CONFLICT: reg = new_reg.update( resource=mes...
If the registration already exists, we should just load it.
entailment
def agree_to_tos(self, regr): """ Accept the terms-of-service for a registration. :param ~acme.messages.RegistrationResource regr: The registration to update. :return: The updated registration resource. :rtype: Deferred[`~acme.messages.RegistrationResource`] ...
Accept the terms-of-service for a registration. :param ~acme.messages.RegistrationResource regr: The registration to update. :return: The updated registration resource. :rtype: Deferred[`~acme.messages.RegistrationResource`]
entailment
def update_registration(self, regr, uri=None): """ Submit a registration to the server to update it. :param ~acme.messages.RegistrationResource regr: The registration to update. Can be a :class:`~acme.messages.NewRegistration` instead, in order to create a new registrat...
Submit a registration to the server to update it. :param ~acme.messages.RegistrationResource regr: The registration to update. Can be a :class:`~acme.messages.NewRegistration` instead, in order to create a new registration. :param str uri: The url to submit to. Must be ...
entailment
def _parse_regr_response(self, response, uri=None, new_authzr_uri=None, terms_of_service=None): """ Parse a registration response from the server. """ links = _parse_header_links(response) if u'terms-of-service' in links: terms_of_service ...
Parse a registration response from the server.
entailment
def _check_regr(self, regr, new_reg): """ Check that a registration response contains the registration we were expecting. """ body = getattr(new_reg, 'body', new_reg) for k, v in body.items(): if k == 'resource' or not v: continue i...
Check that a registration response contains the registration we were expecting.
entailment
def request_challenges(self, identifier): """ Create a new authorization. :param ~acme.messages.Identifier identifier: The identifier to authorize. :return: The new authorization resource. :rtype: Deferred[`~acme.messages.AuthorizationResource`] """ ...
Create a new authorization. :param ~acme.messages.Identifier identifier: The identifier to authorize. :return: The new authorization resource. :rtype: Deferred[`~acme.messages.AuthorizationResource`]
entailment
def _expect_response(cls, response, code): """ Ensure we got the expected response code. """ if response.code != code: raise errors.ClientError( 'Expected {!r} response but got {!r}'.format( code, response.code)) return response
Ensure we got the expected response code.
entailment