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2 classes
2009-01-16
19,010,793
Baranzini SE
2008-11-14
Hum Mol Genet
www.ncbi.nlm.nih.gov/pubmed/19010793
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
Brain lesion load
791 European ancestry cases, 883 European ancestry controls
NA
Illumina [551642]
4
multiple sclerosis
http://purl.obolibrary.org/obo/MONDO_0005301
GCST000265
Genome-wide genotyping array
null
false
NA
false
2009-01-16
19,010,793
Baranzini SE
2008-11-14
Hum Mol Genet
www.ncbi.nlm.nih.gov/pubmed/19010793
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
Multiple sclerosis (severity)
794 European ancestry cases, 883 European ancestry controls
NA
Illumina [551642]
11
multiple sclerosis
http://purl.obolibrary.org/obo/MONDO_0005301
GCST000266
Genome-wide genotyping array
null
false
NA
false
2009-01-12
19,079,261
Willer CJ
2008-12-14
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/19079261
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
Body mass index
32,387 European ancestry individuals
59,082 European ancestry individuals
Affymetrix, Illumina [2399588] (imputed)
11
body mass index
http://www.ebi.ac.uk/efo/EFO_0004340
GCST000298
Genome-wide genotyping array
null
false
NA
false
2011-01-16
21,177,295
Panoutsopoulou K
2010-12-21
Ann Rheum Dis
www.ncbi.nlm.nih.gov/pubmed/21177295
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study.
Osteoarthritis
3,177 European ancestry cases, 4,894 European ancestry controls
10,312 European ancestry cases, 45,861 European ancestry controls, 213 cases, 2,531 controls
Illumina [514898]
0
osteoarthritis
http://purl.obolibrary.org/obo/MONDO_0005178
GCST000923
Genome-wide genotyping array
null
false
NA
false
2008-12-09
18,985,386
Pankratz N
2008-11-06
Hum Genet
www.ncbi.nlm.nih.gov/pubmed/18985386
Genomewide association study for susceptibility genes contributing to familial Parkinson disease.
Parkinson's disease (familial)
1,119 European ancestry cases, 1,127 European ancestry controls
NA
Illumina [328189]
1
Parkinson disease
http://purl.obolibrary.org/obo/MONDO_0005180
GCST000261
Genome-wide genotyping array
null
false
NA
false
2009-01-15
19,079,260
Thorleifsson G
2008-12-14
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/19079260
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.
Weight
72,598 European ancestry individuals, 1,160 African American individuals
Up to 11,036 European ancestry individuals, 32,615 individuals
Illumina [305846]
17
body weight
http://www.ebi.ac.uk/efo/EFO_0004338
GCST000299
Genome-wide genotyping array
null
false
NA
false
2009-01-15
19,079,260
Thorleifsson G
2008-12-14
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/19079260
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.
Body mass index
72,598 European ancestry individuals, 1,160 African American individuals
Up to 11,036 European ancestry individuals, 32,615 individuals
Illumina [305846]
14
body mass index
http://www.ebi.ac.uk/efo/EFO_0004340
GCST000296
Genome-wide genotyping array
null
false
NA
false
2015-05-23
21,208,937
Pichler I
2011-01-04
Hum Mol Genet
www.ncbi.nlm.nih.gov/pubmed/21208937
Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels.
Iron status biomarkers
Up to 5,633 European ancestry individuals
Up to 3,457 European ancestry individuals
Affymetrix, Illumina [~ 2500000] (imputed)
5
iron biomarker measurement
http://www.ebi.ac.uk/efo/EFO_0004461
GCST000935
Genome-wide genotyping array
null
false
NA
false
2009-09-28
18,403,759
Ober C
2008-04-09
N Engl J Med
www.ncbi.nlm.nih.gov/pubmed/18403759
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
YKL-40 levels
632 Hutterite individuals
443 European ancestry cases, 491 European ancestry controls, 206 European ancestry individuals
Affymetrix [290325]
1
YKL40 measurement
http://www.ebi.ac.uk/efo/EFO_0004869
GCST000177
Genome-wide genotyping array
null
false
NA
false
2008-07-22
18,332,876
Kirov G
2008-03-11
Mol Psychiatry
www.ncbi.nlm.nih.gov/pubmed/18332876
A genome-wide association study in 574 schizophrenia trios using DNA pooling.
Schizophrenia
574 European ancestry trios, 605 European ancestry controls
NA
Illumina [~ 550000]
1
schizophrenia
http://purl.obolibrary.org/obo/MONDO_0005090
GCST000163
Genome-wide genotyping array
null
false
NA
false
2008-09-15
17,903,295
Lunetta KL
2007-09-19
BMC Med Genet
www.ncbi.nlm.nih.gov/pubmed/17903295
Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.
Aging traits
1,345 individuals from 330 families
NA
Affymetrix [70897]
10
aging, age at menopause, exercise test, age at death
http://www.ebi.ac.uk/efo/EFO_0022597, http://www.ebi.ac.uk/efo/EFO_0004704, http://www.ebi.ac.uk/efo/EFO_0004328, http://www.ebi.ac.uk/efo/EFO_0005056
GCST000096
Genome-wide genotyping array
null
false
NA
false
2008-09-10
17,903,295
Lunetta KL
2007-09-19
BMC Med Genet
www.ncbi.nlm.nih.gov/pubmed/17903295
Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.
Morbidity-free survival
558 individuals
NA
Affymetrix [70897]
5
disease free survival
http://www.ebi.ac.uk/efo/EFO_0000409
GCST000103
Genome-wide genotyping array
null
false
NA
false
2008-06-16
17,603,485
Gudmundsson J
2007-07-01
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/17603485
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes.
Prostate cancer
1,501 European ancestry cases, 11,290 European ancestry controls
1,992 European ancestry cases, 3,058 European ancestry controls
Illumina [310520]
2
prostate carcinoma
http://www.ebi.ac.uk/efo/EFO_0001663
GCST000050
Genome-wide genotyping array
null
false
NA
false
2008-06-16
17,603,472
Gudbjartsson DF
2007-07-01
Nature
www.ncbi.nlm.nih.gov/pubmed/17603472
Variants conferring risk of atrial fibrillation on chromosome 4q25.
Atrial fibrillation/atrial flutter
550 European ancestry cases, 4,476 European ancestry controls
3,030 European ancestry cases, 14,780 European ancestry controls, 333 Han Chinese ancestry cases, 2,836 Han Chinese ancestry controls
Illumina [316515]
2
atrial fibrillation
http://www.ebi.ac.uk/efo/EFO_0000275
GCST000051
Genome-wide genotyping array
null
false
NA
false
2011-03-02
21,273,288
Del Greco M F
2011-01-27
Hum Mol Genet
www.ncbi.nlm.nih.gov/pubmed/21273288
Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster.
Natriuretic peptide levels
1,325 European ancestry individuals
1,746 European ancestry individuals
Illumina [~ 2500000] (imputed)
3
NT-proBNP measurement
http://www.ebi.ac.uk/efo/EFO_0004745
GCST000957
Genome-wide genotyping array
null
false
NA
false
2011-03-28
21,270,382
Baik I
2011-01-26
Am J Clin Nutr
www.ncbi.nlm.nih.gov/pubmed/21270382
Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men.
Alcohol consumption
1,721 Korean ancestry male individuals
1,113 Korean ancestry male individuals
Affymetrix [315914]
4
alcohol drinking
http://www.ebi.ac.uk/efo/EFO_0004329
GCST000954
Genome-wide genotyping array
null
false
NA
false
2011-05-02
21,460,840
Hollingworth P
2011-04-03
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/21460840
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
Alzheimer's disease
6,688 European ancestry cases, 13,685 European ancestry controls
13,182 European ancestry cases, 26,161 European ancestry controls
Affymetrix, Illumina [496763]
4
Alzheimer disease
http://purl.obolibrary.org/obo/MONDO_0004975
GCST001025
Genome-wide genotyping array
null
false
NA
false
2015-04-22
21,305,692
Belmonte Mahon P
2011-02-08
Am J Med Genet B Neuropsychiatr Genet
www.ncbi.nlm.nih.gov/pubmed/21305692
Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder.
Bipolar disorder (age of onset and psychotic symptoms)
2,836 European ancestry cases, 2,744 European ancestry controls
3,916 European cases, 5,112 controls
Affymetrix, Illumina [2373895] (imputed)
2
psychotic symptoms, age of onset of bipolar disorder
http://www.ebi.ac.uk/efo/EFO_0005940, http://purl.obolibrary.org/obo/OBA_2001019
GCST000969
Genome-wide genotyping array
null
false
NA
false
2010-02-05
20,070,850
Edwards TL
2010-01-13
Ann Hum Genet
www.ncbi.nlm.nih.gov/pubmed/20070850
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.
Parkinson's disease
1,752 European ancestry cases, 1,745 European ancestry controls
NA
Illumina [495715] (imputed)
6
Parkinson disease
http://purl.obolibrary.org/obo/MONDO_0005180
GCST000567
Genome-wide genotyping array
null
false
NA
false
2010-02-04
20,068,591
Van Laer L
2010-01-13
Eur J Hum Genet
www.ncbi.nlm.nih.gov/pubmed/20068591
A genome-wide association study for age-related hearing impairment in the Saami.
Hearing impairment
347 Finnish Saami individuals
NA
Affymetrix [83381]
2
hearing loss
http://www.ebi.ac.uk/efo/EFO_0004238
GCST000566
Genome-wide genotyping array
null
false
NA
false
2010-06-18
20,520,587
Nielsen DA
2010-06-01
Psychiatr Genet
www.ncbi.nlm.nih.gov/pubmed/20520587
Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction.
Heroin addiction
200 European ancestry cases, 150 European ancestry controls, 125 African American cases, 100 African American controls
NA
Affymetrix [up to 113174]
0
heroin dependence
http://www.ebi.ac.uk/efo/EFO_0004240
GCST000690
Genome-wide genotyping array
null
false
NA
false
2011-04-06
21,383,967
Zhernakova A
2011-02-24
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/21383967
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
Celiac disease or Rheumatoid arthritis
4,533 European ancestry celiac disease cases, 5,539 European ancestry rheumatoid arthritis cases, 27,981 European ancestry controls
2,169 European ancestry celiac disease cases, 2,845 European ancestry rheumatoid arthritis cases, 7,199 European ancestry controls
Illumina [472854]
15
immune system disease
http://www.ebi.ac.uk/efo/EFO_0000540
GCST000987
Genome-wide genotyping array
null
false
NA
false
2010-01-19
20,009,918
Shrestha S
2010-01-01
AIDS
www.ncbi.nlm.nih.gov/pubmed/20009918
A genome-wide association study of carotid atherosclerosis in HIV-infected men.
Carotid atherosclerosis in HIV infection
177 European ancestry individuals
NA
Illumina [311194]
7
internal carotid artery thickness, carotid artery disease, carotid artery thickness
http://purl.obolibrary.org/obo/OBA_2050107, http://www.ebi.ac.uk/efo/EFO_0003781, http://purl.obolibrary.org/obo/OBA_2050108
GCST000555
Genome-wide genotyping array
null
false
NA
false
2010-03-17
20,174,558
Tsai FJ
2010-02-19
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/20174558
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.
Type 2 diabetes
995 Han Chinese ancestry cases, 894 Han Chinese ancestry controls
1,803 Han Chinese ancestry cases, 1,473 Han Chinese ancestry controls
Illumina [516737]
3
type 2 diabetes mellitus
http://purl.obolibrary.org/obo/MONDO_0005148
GCST000601
Genome-wide genotyping array
null
false
NA
false
2010-01-28
20,072,603
Guo Y
2010-01-08
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/20072603
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.
Osteoporosis
350 Han Chinese ancestry cases, 350 Han Chinese ancestry controls
390 Han Chinese ancestry cases, 516 Han Chinese ancestry controls
Affymetrix [281533]
1
osteoporosis
http://www.ebi.ac.uk/efo/EFO_0003882
GCST000560
Genome-wide genotyping array
null
false
NA
false
2010-06-23
20,528,957
Oedegaard KJ
2010-06-07
Genes Brain Behav
www.ncbi.nlm.nih.gov/pubmed/20528957
A genome-wide association study of bipolar disorder and comorbid migraine.
Migraine in psychiatric disorder
56 European ancestry bipolar disorder cases, 699 European ancestry bipolar disorder controls
131 European ancestry attention deficit hyperactivity disorder cases, 324 European ancestry attention deficit hyperactivity disorder controls
Affymetrix [724067]
0
migraine disorder
http://purl.obolibrary.org/obo/MONDO_0005277
GCST000695
Genome-wide genotyping array
null
false
NA
false
2015-05-13
21,347,282
Lettre G
2011-02-10
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/21347282
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
Coronary heart disease
260 African American cases, 5,053 African American controls
621 African American cases, 1,629 African American controls
Affymetrix [~ 2740000] (imputed)
3
coronary artery disease
http://www.ebi.ac.uk/efo/EFO_0001645
GCST000972
Genome-wide genotyping array
null
false
NA
false
2015-05-13
21,347,282
Lettre G
2011-02-10
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/21347282
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
Type 2 diabetes
1,264 African American cases, 5,678 African American controls
503 African American cases, 1,656 African American controls
Affymetrix [~ 2740000] (imputed)
2
type 2 diabetes mellitus
http://purl.obolibrary.org/obo/MONDO_0005148
GCST000976
Genome-wide genotyping array
null
false
NA
false
2015-05-13
21,347,282
Lettre G
2011-02-10
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/21347282
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
LDL cholesterol
7,565 African American individuals
3,789 African American and Afro-Caribbean individuals
Affymetrix [~ 2740000] (imputed)
17
low density lipoprotein cholesterol measurement
http://www.ebi.ac.uk/efo/EFO_0004611
GCST000975
Genome-wide genotyping array
null
false
NA
false
2015-05-13
21,347,282
Lettre G
2011-02-10
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/21347282
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
HDL cholesterol
7,813 African American individuals
4,323 African American and Afro-Caribbean individuals
Affymetrix [~ 2740000] (imputed)
18
high density lipoprotein cholesterol measurement
http://www.ebi.ac.uk/efo/EFO_0004612
GCST000974
Genome-wide genotyping array
null
false
NA
false
2015-05-13
21,347,282
Lettre G
2011-02-10
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/21347282
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
Hypertension
4,069 African American cases, 3,848 African American controls
1,372 African American cases, 1,482 African American controls
Affymetrix [~ 2740000] (imputed)
8
hypertension
http://www.ebi.ac.uk/efo/EFO_0000537
GCST000973
Genome-wide genotyping array
null
false
NA
false
2010-09-07
20,639,881
Conde L
2010-07-18
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/20639881
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.
Follicular lymphoma
681 European ancestry cases, 750 European ancestry controls
up to 3,164 European ancestry cases, 6,208 European ancestry controls
Illumina [312768]
3
neoplasm of mature B-cells
http://www.ebi.ac.uk/efo/EFO_0000096
GCST000734
Genome-wide genotyping array
null
false
NA
false
2013-04-24
23,354,978
Rinella ES
2013-01-25
Hum Genet
www.ncbi.nlm.nih.gov/pubmed/23354978
Genetic variants associated with breast cancer risk for Ashkenazi Jewish women with strong family histories but no identifiable BRCA1/2 mutation.
Breast cancer
477 Ashkenazi Jewish cases, 524 Ashkenazi Jewish controls
203 Ashkenazi Jewish cases, 263 Ashkenazi Jewish contols
Affymetrix [435632]
3
breast carcinoma
http://www.ebi.ac.uk/efo/EFO_0000305
GCST001831
Genome-wide genotyping array
null
false
NA
false
2010-07-04
20,487,506
Joubert BR
2010-03-01
Genome Med
www.ncbi.nlm.nih.gov/pubmed/20487506
A whole genome association study of mother-to-child transmission of HIV in Malawi.
HIV (mother-to-child transmission)
100 Malawian ancestry infant cases, 126 Malawian ancestry infant controls
NA
Illumina [586681]
0
HIV mother to child transmission
http://www.ebi.ac.uk/efo/EFO_0004595
GCST000613
Genome-wide genotyping array
null
false
NA
false
2012-01-07
22,137,330
Sanchez-Juan P
2011-11-30
Neurobiol Aging
www.ncbi.nlm.nih.gov/pubmed/22137330
Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk.
Creutzfeldt-Jakob disease (variant)
93 European ancestry cases, 1,504 European ancestry controls
42 European ancestry cases
Affymetrix [287554]
6
Creutzfeldt Jacob Disease
http://www.ebi.ac.uk/efo/EFO_0004226
GCST001334
Genome-wide genotyping array
null
false
NA
false
2010-09-02
20,639,880
Liu X
2010-07-18
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/20639880
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis.
Primary biliary cholangitis
453 European ancestry cases, 945 European ancestry controls,
481 European ancestry cases, 3,706 European ancestry controls
Illumina [276459]
6
biliary liver cirrhosis
http://www.ebi.ac.uk/efo/EFO_0004267
GCST000733
Genome-wide genotyping array
null
false
NA
false
2010-01-29
20,062,061
Chambers JC
2010-01-10
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/20062061
Genetic variation in SCN10A influences cardiac conduction.
Electrocardiographic traits
6,543 Indian Asian ancestry individuals
6,243 Indian Asian ancestry individuals, 5,370 European ancestry individuals
Illumina [303309]
3
electrocardiography
http://www.ebi.ac.uk/efo/EFO_0004327
GCST000564
Genome-wide genotyping array
null
false
NA
false
2013-04-04
23,328,707
Tin A
2013-01-16
Nephrol Dial Transplant
www.ncbi.nlm.nih.gov/pubmed/23328707
Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans.
Beta-trace protein levels
6,720 European ancestry individuals
1,734 African American individuals
Affymetrix [~ 2500000] (imputed)
1
urinary system trait
http://purl.obolibrary.org/obo/OBA_VT1000777
GCST001825
Genome-wide genotyping array
null
false
NA
false
2010-09-27
20,802,204
Baranzini SE
2010-09-01
Brain
www.ncbi.nlm.nih.gov/pubmed/20802204
Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.
Multiple sclerosis--Brain Glutamate Levels
382 cases
NA
Illumina [~ 500000]
5
multiple sclerosis
http://purl.obolibrary.org/obo/MONDO_0005301
GCST000783
Genome-wide genotyping array
null
false
NA
false
2010-06-14
20,512,145
Bei JX
2010-05-30
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/20512145
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
Nasopharyngeal carcinoma
1,583 Chinese ancestry cases, 1,894 Chinese ancestry controls
3,507 Chinese ancestry cases, 3,063 Chinese ancestry controls, 284 Chinese ancestry trios
Illumina [464328]
7
nasopharyngeal neoplasm
http://www.ebi.ac.uk/efo/EFO_0004252
GCST000687
Genome-wide genotyping array
null
false
NA
false
2010-09-23
20,801,718
Laaksovirta H
2010-08-27
Lancet Neurol
www.ncbi.nlm.nih.gov/pubmed/20801718
Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study.
Amyotrophic lateral sclerosis
405 European ancestry cases, 497 European ancestry controls
NA
Illumina [318167]
2
amyotrophic lateral sclerosis
http://purl.obolibrary.org/obo/MONDO_0004976
GCST000781
Genome-wide genotyping array
null
false
NA
false
2009-05-07
19,389,651
Smith JG
2009-02-15
Heart Rhythm
www.ncbi.nlm.nih.gov/pubmed/19389651
Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae.
Electrocardiographic conduction measures
1,262 Kosraen individuals
NA
Affymetrix [338049]
7
electrocardiography
http://www.ebi.ac.uk/efo/EFO_0004327
GCST000344
Genome-wide genotyping array
null
false
NA
false
2009-09-09
19,714,205
Hancock DB
2009-08-28
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/19714205
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children.
Asthma (childhood onset)
492 Mexican ancestry trios
177 Mexican ancestry trios
Illumina [520767]
1
childhood onset asthma
http://purl.obolibrary.org/obo/MONDO_0005405
GCST000468
Genome-wide genotyping array
null
false
NA
false
2009-05-07
18,839,057
Lesch KP
2008-10-07
J Neural Transm (Vienna)
www.ncbi.nlm.nih.gov/pubmed/18839057
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.
Attention deficit hyperactivity disorder
343 European ancestry cases, 250 European ancestry controls, 54 controls
NA
Affymetrix [504219]
26
attention deficit hyperactivity disorder
http://www.ebi.ac.uk/efo/EFO_0003888
GCST000246
Genome-wide genotyping array
null
false
NA
false
2009-11-18
19,851,299
Johansson A
2009-10-22
Obesity (Silver Spring)
www.ncbi.nlm.nih.gov/pubmed/19851299
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
Weight
Up to 3,925 European individuals
NA
Illumina [318237]
9
body weight
http://www.ebi.ac.uk/efo/EFO_0004338
GCST000511
Genome-wide genotyping array
null
false
NA
false
2009-11-18
19,851,299
Johansson A
2009-10-22
Obesity (Silver Spring)
www.ncbi.nlm.nih.gov/pubmed/19851299
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
Body mass index
1,079 South Tyrolean individuals, 790 Dutch founder individuals, 2,060 European ancestry individuals
NA
Illumina [318237]
10
body mass index
http://www.ebi.ac.uk/efo/EFO_0004340
GCST000512
Genome-wide genotyping array
null
false
NA
false
2009-12-04
19,897,590
Schaefer AS
2009-11-06
Hum Mol Genet
www.ncbi.nlm.nih.gov/pubmed/19897590
A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.
Periodontitis
283 European ancestry cases, 972 European ancestry controls
155 European ancestry cases, 341 European ancestry controls
Affymetrix [345646]
1
periodontitis
http://www.ebi.ac.uk/efo/EFO_0000649
GCST000521
Genome-wide genotyping array
null
false
NA
false
2009-08-21
19,620,980
Skibola CF
2009-07-20
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/19620980
Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.
Follicular lymphoma
189 European ancestry cases, 592 European controls
456 European ancestry cases, 2,785 European ancestry controls
Illumina [~ 500000]
1
neoplasm of mature B-cells
http://www.ebi.ac.uk/efo/EFO_0000096
GCST000448
Genome-wide genotyping array
null
false
NA
false
2010-09-28
20,838,585
Smith EN
2010-09-09
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/20838585
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.
Cardiovascular risk factors (age interaction)
525 European ancestry individuals
2,442 Finnish ancestry individuals
Illumina [2173391] (imputed)
4
triglyceride measurement, low density lipoprotein cholesterol measurement, waist circumference, cardiovascular disease, high density lipoprotein cholesterol measurement, age at assessment
http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://purl.obolibrary.org/obo/OBA_1001085, http://www.ebi.ac.uk/efo/EFO_0000319, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0008007
GCST000789
Genome-wide genotyping array
null
false
NA
true
2017-09-12
20,838,585
Smith EN
2010-09-09
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/20838585
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.
Cardiovascular risk factors
525 European ancestry individuals
2,442 Finnish ancestry individuals
Illumina [2173391] (imputed)
2
triglyceride measurement, low density lipoprotein cholesterol measurement, waist circumference, cardiovascular disease, high density lipoprotein cholesterol measurement
http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://purl.obolibrary.org/obo/OBA_1001085, http://www.ebi.ac.uk/efo/EFO_0000319, http://www.ebi.ac.uk/efo/EFO_0004612
GCST004704
Genome-wide genotyping array
null
false
NA
false
2012-01-27
22,199,011
Murabito JM
2011-12-23
Circ Cardiovasc Genet
www.ncbi.nlm.nih.gov/pubmed/22199011
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.
Ankle-brachial index
38,376 European ancestry individuals, 2,133 Erasmus Rucphen individuals, 1,183 Old Order Amish individuals
16,717 European ancestry individuals
Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)
2
ankle brachial index
http://www.ebi.ac.uk/efo/EFO_0003912
GCST001361
Genome-wide genotyping array
null
false
NA
false
2009-08-07
19,584,346
Vasan RS
2009-07-08
JAMA
www.ncbi.nlm.nih.gov/pubmed/19584346
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
Aortic root size
12,612 European ancestry individuals
4,094 European ancestry individuals
Affymetrix, Illumina [~ 2500000] (imputed)
6
bulb of aorta size
http://purl.obolibrary.org/obo/OBA_0005483
GCST000442
Genome-wide genotyping array
null
false
NA
false
2009-08-07
19,584,346
Vasan RS
2009-07-08
JAMA
www.ncbi.nlm.nih.gov/pubmed/19584346
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
Cardiac structure and function
12,612 European ancestry individuals
4,094 European ancestry individuals
Affymetrix, Illumina [~ 2500000] (imputed)
4
cardiovascular measurement
http://www.ebi.ac.uk/efo/EFO_0004298
GCST000441
Genome-wide genotyping array
null
false
NA
false
2010-09-23
20,729,853
Wang LD
2010-08-22
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/20729853
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54.
Esophageal cancer
1,077 Han Chinese ancestry cases, 1,733 Han Chinese ancestry controls
7,673 Han Chinese ancestry cases, 11,013 Han Chinese ancestry controls, 303 Uygur-Kazakh Chinese ancestry cases, 537 Uygur-Kazakh Chinese ancestry controls
Illumina [506666]
0
esophageal carcinoma
http://www.ebi.ac.uk/efo/EFO_0002916
GCST000776
Genome-wide genotyping array
null
false
NA
false
2009-12-01
19,874,204
Guo Y
2009-10-29
J Bone Miner Res
www.ncbi.nlm.nih.gov/pubmed/19874204
IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study.
Bone mineral density
983 European ancestry individuals
2,557 European ancestry individuals from 750 families
Affymetrix [342854]
2
bone tissue density
http://purl.obolibrary.org/obo/OBA_1000110
GCST000515
Genome-wide genotyping array
null
false
NA
false
2009-11-12
19,850,125
Kim HJ
2009-10-19
Neurobiol Dis
www.ncbi.nlm.nih.gov/pubmed/19850125
Common CYP7A1 promoter polymorphism associated with risk of neuromyelitis optica.
Neuromyelitis optica
53 Korean ancestry cases, 240 Korean ancestry controls
37 Korean ancestry cases
Illumina [288025]
0
neuromyelitis optica
http://www.ebi.ac.uk/efo/EFO_0004256
GCST000508
Genome-wide genotyping array
null
false
NA
false
2008-06-16
18,311,140
Hunt KA
2008-03-02
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/18311140
Newly identified genetic risk variants for celiac disease related to the immune response.
Celiac disease
767 European ancestry cases, 1,422 European ancestry controls
1,643 European ancestry cases, 3,406 European ancestry controls
Illumina [310605]
8
celiac disease
http://www.ebi.ac.uk/efo/EFO_0001060
GCST000157
Genome-wide genotyping array
null
false
NA
false
2008-06-16
18,264,096
Thomas G
2008-02-10
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/18264096
Multiple loci identified in a genome-wide association study of prostate cancer.
Prostate cancer
1,172 European ancestry cases, 1,157 European ancestry controls
3,941 European ancestry cases, 3,964 European ancestry controls
Illumina [527869]
7
prostate carcinoma
http://www.ebi.ac.uk/efo/EFO_0001663
GCST000154
Genome-wide genotyping array
null
false
NA
false
2009-12-18
19,944,697
Karlsen TH
2009-11-25
Gastroenterology
www.ncbi.nlm.nih.gov/pubmed/19944697
Genome-wide association analysis in primary sclerosing cholangitis.
Primary sclerosing cholangitis
285 European ancestry cases, 298 European ancestry controls
766 European ancestry cases, 2,935 European ancestry controls
Affymetrix [375487]
0
sclerosing cholangitis
http://www.ebi.ac.uk/efo/EFO_0004268
GCST000534
Genome-wide genotyping array
null
false
NA
false
2015-04-23
19,875,614
Paterson AD
2009-10-29
Diabetes
www.ncbi.nlm.nih.gov/pubmed/19875614
A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose.
Glycemic control in type 1 diabetes (HbA1c)
667 European ancestry conventional treatment cases, 637 European ancestry intensive treatment cases
1,382 European ancestry cases
Affymetrix, Illumina [2518578] (imputed)
0
HbA1c measurement
http://www.ebi.ac.uk/efo/EFO_0004541
GCST000516
Genome-wide genotyping array
null
false
NA
false
2008-09-17
18,325,910
Liu YJ
2008-03-05
Hum Mol Genet
www.ncbi.nlm.nih.gov/pubmed/18325910
Genome-wide association scans identified CTNNBL1 as a novel gene for obesity.
Obesity
1,000 European ancestry individuals
896 European ancestry cases, 2,916 European ancestry controls
Affymetrix [379319]
0
obesity
http://www.ebi.ac.uk/efo/EFO_0001073
GCST000159
Genome-wide genotyping array
null
false
NA
false
2008-09-17
18,327,256
Doring A
2008-03-09
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/18327256
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.
Urate levels
1,644 European ancestry individuals
9,947 European ancestry individuals
Affymetrix [335152]
1
urate measurement
http://www.ebi.ac.uk/efo/EFO_0004531
GCST000161
Genome-wide genotyping array
null
false
NA
false
2009-09-04
19,648,919
Song H
2009-08-02
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/19648919
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.
Ovarian cancer
1,817 European ancestry cases, 2,353 European ancestry controls
6,944 European ancestry cases, 9,477 European ancestry controls
Illumina [up to 2000000] (imputed)
1
ovarian carcinoma
http://www.ebi.ac.uk/efo/EFO_0001075
GCST000455
Genome-wide genotyping array
null
false
NA
false
2009-09-28
19,729,612
Paterson AD
2009-09-03
Arterioscler Thromb Vasc Biol
www.ncbi.nlm.nih.gov/pubmed/19729612
Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin.
Soluble E-selectin levels
685 European ancestry individuals with type 1 diabetes
477 European ancestry individuals
Illumina [~ 841000]
1
E-selectin amount
http://purl.obolibrary.org/obo/OBA_2050324
GCST000476
Genome-wide genotyping array
null
false
NA
false
2008-09-17
18,327,257
Vitart V
2008-03-09
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/18327257
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.
Urate levels
794 European ancestry individuals
706 European ancestry individuals
Illumina [308140]
1
urate measurement
http://www.ebi.ac.uk/efo/EFO_0004531
GCST000160
Genome-wide genotyping array
null
false
NA
false
2009-07-24
19,587,794
Nolte IM
2009-07-09
PLoS One
www.ncbi.nlm.nih.gov/pubmed/19587794
Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies.
QT interval
3,558 European ancestry individuals
29,527 European ancestry individuals
Affymetrix, Illumina [~ 2399142] (imputed)
2
QT interval
http://www.ebi.ac.uk/efo/EFO_0004682
GCST000444
Genome-wide genotyping array
null
false
NA
false
2013-11-29
23,727,862
Savage SA
2013-06-02
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/23727862
Genome-wide association study identifies two susceptibility loci for osteosarcoma.
Osteosarcoma
694 European ancestry cases, 2,703 European ancestry controls
247 European ancestry cases, 550 European ancestry controls
Illumina [698968]
6
osteosarcoma
http://www.ebi.ac.uk/efo/EFO_0000637
GCST002056
Genome-wide genotyping array
null
false
NA
false
2010-03-29
20,304,703
Li Y
2010-03-19
Lancet Oncol
www.ncbi.nlm.nih.gov/pubmed/20304703
Genetic variants and risk of lung cancer in never smokers: a genome-wide association study.
Lung cancer
364 European ancestry cases, 364 European ancestry controls, 13 cases, 13 controls
446 European ancestry cases, 853 European ancestry controls, 65 cases, 154 controls
Illumina [331918]
1
lung carcinoma
http://www.ebi.ac.uk/efo/EFO_0001071
GCST000633
Genome-wide genotyping array
null
false
NA
false
2013-11-15
23,698,163
Gong J
2013-05-21
Nutrients
www.ncbi.nlm.nih.gov/pubmed/23698163
Genome-wide association study of serum selenium concentrations.
Serum selenium levels
582 European ancestry individuals
621 European ancestry individuals
Illumina [2474333]
4
serum selenium amount
http://purl.obolibrary.org/obo/OBA_2050059
GCST002028
Genome-wide genotyping array
null
false
NA
false
2013-02-27
23,284,291
Hancock DB
2012-12-20
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/23284291
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Pulmonary function (smoking interaction)
50,047 European ancestry individuals
NA
NR [~ 2500000] (imputed)
53
pulmonary function measurement, smoking behavior trait
http://www.ebi.ac.uk/efo/EFO_0003892, http://purl.obolibrary.org/obo/OBA_2050116
GCST001784
Genome-wide genotyping array
null
false
NA
true
2008-09-25
18,794,855
Kiemeney LA
2008-09-14
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/18794855
Sequence variant on 8q24 confers susceptibility to urinary bladder cancer.
Urinary bladder cancer
1,803 European ancestry cases, 34,336 European ancestry controls
2,165 European ancestry cases, 3,800 European ancestry controls
Illumina [302140]
2
urinary bladder carcinoma
http://purl.obolibrary.org/obo/MONDO_0004986
GCST000231
Genome-wide genotyping array
null
false
NA
false
2010-05-24
20,418,889
Liu JZ
2010-04-25
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/20418889
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
Smoking behavior
41,150 European ancestry individuals
120,516 European ancestry individuals
Affymetrix, Illumina [NR] (imputed)
1
smoking behavior
http://www.ebi.ac.uk/efo/EFO_0004318
GCST000668
Genome-wide genotyping array
null
false
NA
false
2009-10-06
19,779,542
Nakanishi H
2009-09-25
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/19779542
A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.
Myopia (pathological)
297 Japanese ancestry cases, 934 Japanese ancestry controls
533 Japanese ancestry cases, 977 Japanese ancestry controls
Illumina [411777]
1
pathological myopia
http://www.ebi.ac.uk/efo/EFO_0004207
GCST000491
Genome-wide genotyping array
null
false
NA
false
2009-12-03
19,902,172
Palmer ND
2009-11-10
Diabetologia
www.ncbi.nlm.nih.gov/pubmed/19902172
Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study.
Insulin-related traits
229 Hispanic individuals from 34 families
814 Hispanic family members
Illumina [309200]
0
insulin measurement
http://www.ebi.ac.uk/efo/EFO_0004467
GCST000526
Genome-wide genotyping array
null
false
NA
false
2010-03-22
20,175,129
Zhao LJ
2009-12-11
J Bone Miner Res
www.ncbi.nlm.nih.gov/pubmed/20175129
Genome-wide association study for femoral neck bone geometry.
Femoral neck bone geometry
987 European ancestry individuals
1,488 European ancestry individuals, 2,118 Chinese ancestry individuals
Affymetrix [379319]
0
femoral neck bone geometry
http://www.ebi.ac.uk/efo/EFO_0004511
GCST000541
Genome-wide genotyping array
null
false
NA
false
2011-04-11
21,378,988
Coronary Artery Disease (C4D) Genetics Consortium
2011-03-06
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/21378988
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
Coronary heart disease
8,424 European ancestry cases, 7,268 European ancestry controls, 6,996 South Asian ancestry cases, 7,794 South Asian ancestry controls
18,049 European ancestry cases, 16,357 European ancestry controls, 3,359 South Asian ancestry cases, 2,828 South Asian ancestry controls
Illumina [574919]
19
coronary artery disease
http://www.ebi.ac.uk/efo/EFO_0001645
GCST000999
Genome-wide genotyping array
null
false
NA
false
2010-05-06
20,385,826
Neale BM
2010-04-12
Proc Natl Acad Sci U S A
www.ncbi.nlm.nih.gov/pubmed/20385826
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).
Age-related macular degeneration
979 cases, 1,709 controls
868 European ancestry cases, 410 European ancestry controls, 4,921 cases, 3,824 controls
Affymetrix [632932]
11
age-related macular degeneration
http://www.ebi.ac.uk/efo/EFO_0001365
GCST000653
Genome-wide genotyping array
null
false
NA
false
2010-07-04
20,548,944
Hsu YH
2010-06-10
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/20548944
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.
Osteoporosis-related phenotypes
2,038 European ancestry female individuals, 1,531 European ancestry male individuals
5,595 European ancestry female individuals, 2,126 European ancestry male individuals
Affymetrix [433510]
7
osteoporosis
http://www.ebi.ac.uk/efo/EFO_0003882
GCST000698
Genome-wide genotyping array
null
false
NA
false
2010-04-12
20,304,771
Newman AB
2010-03-18
J Gerontol A Biol Sci Med Sci
www.ncbi.nlm.nih.gov/pubmed/20304771
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.
Longevity
1,836 European ancestry long-lived individuals, 1,955 European ancestry controls
2,594 European ancestry long-lived individuals, 3,431 European ancestry controls
Affymetrix, Illumina [2287520] (imputed)
1
life span determination trait
http://purl.obolibrary.org/obo/OBA_VT0005372
GCST000632
Genome-wide genotyping array
null
false
NA
false
2009-11-04
19,798,445
Hicks AA
2009-10-02
PLoS Genet
www.ncbi.nlm.nih.gov/pubmed/19798445
Genetic determinants of circulating sphingolipid concentrations in European populations.
Sphingolipid levels
4,110 European ancestry individuals
NA
Illumina [318237]
5
sphingolipid level
http://purl.obolibrary.org/obo/OBA_1000965
GCST000493
Genome-wide genotyping array
null
false
NA
false
2010-06-22
20,526,339
Quan C
2010-06-06
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/20526339
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.
Vitiligo
1,117 Han Chinese ancestry cases, 1,429 Han Chinese ancestry controls
6,623 East Asian ancestry cases, 10,740 East Asian ancestry controls
Illumina [493909]
4
Vitiligo
http://www.ebi.ac.uk/efo/EFO_0004208
GCST000692
Genome-wide genotyping array
null
false
NA
false
2011-05-11
21,483,023
Wu X
2011-04-11
J Natl Cancer Inst
www.ncbi.nlm.nih.gov/pubmed/21483023
Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy.
Response to platinum-based chemotherapy in non-small-cell lung cancer
327 European ancestry individuals
735 European ancestry individuals
Illumina [307260]
1
trait in response to platinum
http://purl.obolibrary.org/obo/OBA_2040037
GCST001035
Genome-wide genotyping array
null
false
NA
false
2011-01-11
21,150,878
Ferreira MA
2010-12-08
Eur J Hum Genet
www.ncbi.nlm.nih.gov/pubmed/21150878
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.
Asthma
986 European ancestry cases, 1,846 European ancestry controls
391 European ancestry cases, 213 European ancestry controls
Illumina [~ 2380000] (imputed)
1
asthma
http://purl.obolibrary.org/obo/MONDO_0004979
GCST000910
Genome-wide genotyping array
null
false
NA
false
2013-05-02
18,514,160
Arnaud-Lopez L
2008-06-01
Am J Hum Genet
www.ncbi.nlm.nih.gov/pubmed/18514160
Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.
Thyroid stimulating hormone levels
4,300 Sardinian indivduals
1,164 European ancestry individuals, 1,136 Old Order Amish individuals, 1,858 Sardinian individuals
Affymetrix [362129]
1
thyroid function
http://www.ebi.ac.uk/efo/EFO_0004296
GCST000199
Genome-wide genotyping array
null
false
NA
false
2011-04-11
21,378,990
Schunkert H
2011-03-06
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/21378990
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
Coronary heart disease
22,233 European ancestry cases, 64,762 European ancestry controls
56,682 European ancestry cases and controls
Affymetrix, Illumina [~ 2300000] (imputed)
30
coronary artery disease
http://www.ebi.ac.uk/efo/EFO_0001645
GCST000998
Genome-wide genotyping array
null
true
http://ftp.ebi.ac.uk/pub/databases/gwas/summary_statistics/GCST000001-GCST001000/GCST000998
false
2009-03-31
19,260,141
Zemunik T
2009-02-01
Croat Med J
www.ncbi.nlm.nih.gov/pubmed/19260141
Genome-wide association study of biochemical traits in Korcula Island, Croatia.
Biochemical measures
898 Korculan (founder/genetic isolate) individuals
NA
Illumina [316730]
17
total cholesterol measurement, serum albumin amount, triglyceride measurement, low density lipoprotein cholesterol measurement, circulating fibrinogen levels, uric acid measurement, high density lipoprotein cholesterol measurement
http://www.ebi.ac.uk/efo/EFO_0004574, http://purl.obolibrary.org/obo/OBA_2050068, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://purl.obolibrary.org/obo/OBA_0000061, http://www.ebi.ac.uk/efo/EFO_0004761, http://www.ebi.ac.uk/efo/EFO_0004612
GCST000328
Genome-wide genotyping array
null
false
NA
false
2010-11-15
20,932,654
Kerns SL
2010-10-05
Int J Radiat Oncol Biol Phys
www.ncbi.nlm.nih.gov/pubmed/20932654
Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.
Erectile dysfunction and prostate cancer treatment
27 African American cases, 52 African American controls
NA
Affymetrix [512497]
23
response to radiation, prostate carcinoma, erectile dysfunction
http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0001663, http://www.ebi.ac.uk/efo/EFO_0004234
GCST000824
Genome-wide genotyping array
null
false
NA
false
2010-06-21
20,516,156
Lewis CM
2010-06-01
Am J Psychiatry
www.ncbi.nlm.nih.gov/pubmed/20516156
Genome-wide association study of major recurrent depression in the U.K. population.
Major depressive disorder
1,636 European ancestry cases, 1,594 European ancestry controls
1,418 European ancestry cases, 1,918 European ancestry controls
Illumina [471747]
4
major depressive disorder
http://purl.obolibrary.org/obo/MONDO_0002009
GCST000689
Genome-wide genotyping array
null
false
NA
false
2009-05-11
19,403,135
Yamada Y
2009-04-05
Atherosclerosis
www.ncbi.nlm.nih.gov/pubmed/19403135
Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study.
Stroke (ischemic)
131 Japanese ancestry cases, 135 Japanese ancestry controls
776 Japanese ancestry cases, 5,205 Japanese ancestry controls
Affymetrix [~ 520000]
0
stroke
http://www.ebi.ac.uk/efo/EFO_0000712
GCST000373
Genome-wide genotyping array
null
false
NA
false
2010-03-15
20,167,578
Barbalic M
2010-02-18
Hum Mol Genet
www.ncbi.nlm.nih.gov/pubmed/20167578
Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels.
Soluble levels of adhesion molecules
Up to 9,813 European ancestry individuals
NA
Affymetrix, Illumina [~ 2500000] (imputed)
5
adhesion molecule measurement
http://www.ebi.ac.uk/efo/EFO_0004522
GCST000599
Genome-wide genotyping array
null
false
NA
false
2009-04-01
19,303,062
Tanaka T
2009-03-18
Am J Hum Genet
www.ncbi.nlm.nih.gov/pubmed/19303062
Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.
Folate pathway vitamin levels
2,934 European ancestry individuals
686 European ancestry individuals
Affymetrix, Illumina [~ 2500000] (imputed)
5
vitamin B measurement, vitamin B12 measurement, vitamin B6 measurement
http://www.ebi.ac.uk/efo/EFO_0004843, http://www.ebi.ac.uk/efo/EFO_0004620, http://www.ebi.ac.uk/efo/EFO_0004621
GCST000358
Genome-wide genotyping array
null
false
NA
false
2011-04-13
21,423,239
Willour VL
2011-03-25
Mol Psychiatry
www.ncbi.nlm.nih.gov/pubmed/21423239
A genome-wide association study of attempted suicide.
Suicide attempts in bipolar disorder
1,201 European and unknown ancestry attempters, 1,497 European and unknown ancestry non-attempters
1,295 attempters, 1,822 non-attempters
Affymetrix, Illumina [2408051] (imputed)
3
attempted suicide
http://www.ebi.ac.uk/efo/EFO_0004321
GCST001015
Genome-wide genotyping array
null
false
NA
false
2011-01-03
21,041,692
Denny JC
2010-11-01
Circulation
www.ncbi.nlm.nih.gov/pubmed/21041692
Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science.
Atrioventricular conduction
2,334 European ancestry individuals
NA
Illumina [514999]
5
heart function attribute
http://purl.obolibrary.org/obo/OBA_2045275
GCST000852
Genome-wide genotyping array
null
false
NA
false
2011-01-14
21,130,836
Luciano M
2010-12-03
Biol Psychol
www.ncbi.nlm.nih.gov/pubmed/21130836
Whole genome association scan for genetic polymorphisms influencing information processing speed.
Information processing speed
Up to 4,039 European ancestry individuals
NA
Illumina [~ 610000]
25
information processing speed
http://www.ebi.ac.uk/efo/EFO_0004363
GCST000905
Genome-wide genotyping array
null
false
NA
false
2011-01-11
21,057,379
Curtis D
2010-11-04
Psychiatr Genet
www.ncbi.nlm.nih.gov/pubmed/21057379
Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.
Bipolar disorder and schizophrenia
506 European ancestry bipolar 1 disorder cases, 523 European ancestry schizophrenia cases, 505 European ancestry controls
NA
Affymetrix [302482]
6
mental or behavioural disorder
http://www.ebi.ac.uk/efo/EFO_0000677
GCST000862
Genome-wide genotyping array
null
false
NA
false
2011-04-13
21,441,570
Grassi MA
2011-03-26
Hum Mol Genet
www.ncbi.nlm.nih.gov/pubmed/21441570
Genome-wide meta-analysis for severe diabetic retinopathy.
Diabetic retinopathy
973 European ancestry cases, 1,856 European ancestry controls
NA
Affymetrix, Illumina [2543887] (imputed)
19
diabetic retinopathy
http://www.ebi.ac.uk/efo/EFO_0003770
GCST001017
Genome-wide genotyping array
null
false
NA
false
2011-01-03
21,184,583
Zlojutro M
2010-11-02
Am J Med Genet B Neuropsychiatr Genet
www.ncbi.nlm.nih.gov/pubmed/21184583
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.
Event-related brain oscillations
431 European ancestry alcohol dependence cases, 340 European ancestry controls, 209 African American alcohol dependence cases, 84 African American controls
683 alcohol dependence cases and 412 controls from multiplex families
Illumina [951071]
3
event-related brain oscillation
http://www.ebi.ac.uk/efo/EFO_0004358
GCST000857
Genome-wide genotyping array
null
false
NA
false
2012-02-25
22,290,723
Ryu J
2012-01-30
Hum Mutat
www.ncbi.nlm.nih.gov/pubmed/22290723
Association of glycosylated hemoglobin with the gene encoding CDKAL1 in the Korean Association Resource (KARE) study.
Glycated hemoglobin levels
4,275 Korean ancestry individuals
3,782 Korean ancestry individuals
Affymetrix [1693116] (imputed)
1
HbA1c measurement
http://www.ebi.ac.uk/efo/EFO_0004541
GCST001393
Genome-wide genotyping array
null
false
NA
false
2013-10-24
23,563,609
Wheeler E
2013-04-07
Nat Genet
www.ncbi.nlm.nih.gov/pubmed/23563609
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.
Obesity (early onset extreme)
1,509 European ancestry cases, 5,380 European ancestry controls
971 European ancestry cases, 1,990 European ancestry controls
Affymetrix [~ 2000000] (imputed)
18
obesity
http://www.ebi.ac.uk/efo/EFO_0001073
GCST001957
Genome-wide genotyping array
null
false
NA
false
2009-01-21
19,118,814
Beecham GW
2009-01-03
Am J Hum Genet
www.ncbi.nlm.nih.gov/pubmed/19118814
Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.
Alzheimer's disease
492 European ancestry cases, 496 European ancestry controls
238 European ancestry cases, 220 European ancestry controls
Illumina [~ 2500000] (imputed)
3
Alzheimer disease
http://purl.obolibrary.org/obo/MONDO_0004975
GCST000310
Genome-wide genotyping array
null
false
NA
false