accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 16 2.75k | function stringlengths 6 5.51k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q26474 | LACH_SCHAM | Lachesin | Schistocerca | MDLRLYTIFVGFFSVVYAQRTPTISYISQEQIKDIGGTVELECSVQYAQDYPVLWMKVDRNRQVDPLPISTGSSLIIRDSRFALRYDTASSTYTLQIKDIQETDAGFYQCQVIIGLNNKITAEVDLQVRRPPVISDNSTRSLVVSEGQAVRLECYAGGYPAPRVSWRRENNAILPTGGSIYRGNVLKISRIGKEDRGTYYCVAENGVGKGARRNIAVEVEFPPVITVPRPRLGQALQYDMDLECHVEAYPPPAITWLKDETVLSNNQHYSISHFATADEFTDTTRVITIEKRQYGKYQCKAANKLGEAREEVELFETIIP... | May play a role in early neuronal differentiation and axon outgrowth. | Q26474 |
B6JET4 | RL4_AFIC5 | 50S ribosomal protein L4 | Afipia | MELNVTTLEGKAAGSVNLSDTIFGLEPRTDIIQRVVNWQLAKRQAGTHKTKGRAEIARTGKKMYKQKGTGGARHGSARVPQFRGGGRAFGPVVRSHAYDLPKKVRALGLRHALSAKAKDGSLVVLDNAELKDAKTKALIGHFSGLGLTSALIVDGAEVNNGFAQAARNIPHIDVLPIQGINVYDILRRQKLVLTKAAVDALEARFK | Forms part of the polypeptide exit tunnel. | B6JET4 |
C1GB49 | LIS1_PARBD | nudF homolog | Paracoccidioides | MSQLLTARQAEELHKAMIAYLLSANLPKSAAALREELADSVQLDDSTAKKYEGLLEKKWTSVVRLQKKIMDLESRNNALQSELDSATPTSLARRNQDPVSWLPHAPARHILQSHREPVTCVGFHPVFSSLASGSDDTTIKIWDWELGELERTIKGHTKAVLDVDYGGPRGGTLLASCSSDLTIKLWDPSDGYKNIRTLPGHDHSVSAVRFIPSGAAGSPLSGNLLVSASRDKTLRIWDVTTGYCVKTLRGHVDWVRDVAASPDGRFLFSAGNDQVARLWDVSSGETKSTFLGHEHAVECVAFAPPTSYPHLSALAGLKKA... | Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) trans... | C1GB49 |
Q606H8 | RS6_METCA | 30S ribosomal protein S6 | Methylococcus | MRHYEIVFMVHPDQSGQVPAMIERYRSIIEGAAGRIHRLEDWGRRQLAYPIAKLHKAHYVLMNIECDQATLEELESGFRFNDAVLRSLTIRRDEAVTEPSALARSGSDAEADRAPADEGSVEAAGAEPGSEAEAEA | Binds together with S18 to 16S ribosomal RNA. | Q606H8 |
C6HSY8 | ARGJ_AJECH | Arginine biosynthesis bifunctional protein ArgJ beta chain | Histoplasma | MRNPKSFCVVAGFVRLPKSSLGQVRYYSIPNDVSIPASKGKFIPGSGTYPKGFLVAGAHAGVKESNTQFPDVALICSETPCSAAAVFTTNKFQAAPVQVSKQVLEKRQGAGIRGVVINSGCANAVTGKGGLEDAKMMSAKVDECNGTPSTGPQDTSTLVMSTGVIGQRLPIKKILDAIPTAHSNLASTHSTWLATARAICTTDTFPKLLSRTFTLPSSPNRQYCLAGMTKGAGMIHPNMATLLGILCTDVPISPSALKALLTHAVSRSFNAISIDGDTSTNDTIALLANGAAGGEAITTTSSQDYAAMQTILTSFAQSLA... | Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. | C6HSY8 |
Q5P720 | TGT_AROAE | tRNA-guanine transglycosylase | Aromatoleum | MQFELLAQHGAARRGRLTLAHGTVDTPAFMPVGTYGTVKAMTPAALADTGAQICLGNTFHLWLRPGLDVVAAHGGLHRFMNWDRPILTDSGGFQVFSLGALRKISEEGVKFASPIDGAKLFLTPEESMRIQTVLNSDIAMIFDECTPHPATHDEAAKSMQLSLRWARRSRDEFDRLANPNALFGIVQGGMFEDLRDESLAALDAIGFSGYAIGGLSVGEPKEDMARILAHTAPRLPAGRPRYLMGVGTPEDIVAGVAAGIDMFDCVMPTRNARNGWLFTRYGDIKIKNATHKQDTRPLDPSCDCYTCRNFSRAYLHHLHR... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | Q5P720 |
D9U2A6 | KA291_LYCMC | Toxin LmKTx2 | Lychas | MKSVCGVLIILVVLTTMLSISTFSTVGAEGDCPISEAIKCVEKCKEKVEVCEPGVCKCSG | Weakly inhibits the Kv1.3/KCNA3 channel (1 uM of the toxin inhibits currents by 13.2%) and Kv7.1/KCNQ1 channel (10 uM of the toxin inhibits currents by 27.7%). | D9U2A6 |
Q1BS32 | HIS3_BURCA | Phosphoribosyl-AMP cyclohydrolase | Burkholderia cepacia complex | MNTETKSLPAWLDKVRWDDNGLVPVIAQEASTNDVLMFAWMNREALAKTIETQRAVYYSRSRKRLWFKGEESGHVQHVHEVRLDCDEDVVLLKVEQVSGIACHTGRHSCFFQKFEGTVDGGDWVAVEPVLKDPEHIYK | Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Q1BS32 |
Q8TIQ4 | CRCB2_METAC | Putative fluoride ion transporter CrcB 2 | Methanosarcina | MPSQDKEIDKIFLIGAGGFLGAVCRFLLCELVEGQLGILSVNVIGSFMLGMIMYDTEYLGFIGPKGKIAFGTGFMGAFTTFSTFAVQSFSLPFIPALGNISANIFLTLTGVFFGRSVIKALSSREI | Important for reducing fluoride concentration in the cell, thus reducing its toxicity. | Q8TIQ4 |
B2ITP0 | RL18_NOSP7 | 50S ribosomal protein L18 | Nostoc | MKLTRRESKNRRHRRVRGKVVGSPERPRLAVFRSNEHIYAQVIDDSQHQTIVAASTLEPELKSSLASGANRDASVQVGKLIAVRSLEKGITKVVFDRGGNLYHGRVKALADAAREAGLDF | This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | B2ITP0 |
A5WEG6 | CYSG_PSYWF | Sirohydrochlorin ferrochelatase | Psychrobacter | MNTFPLFFKLTNQPVLIVGGGEVAQRKADLLSRAGACITILAPQISQEIHQLLSDERHTLITAHYDKKYIDGKRIVIAGTDDEALNHQVHADCKALNIPVNVVDTPPLCDFIFPAIVDRNPIVIGISSNGKAPVLARLTRARLETLIPQGYGKLAKLAGDMRDEVKSKIPTLTGRRQFWEKAFEGKVSELMFAGRSVEAEQALKQQLEQTHQQLSSNSDVKQADPKSVGEVYIVGAGPGDPELLTFKALRLMQQADIVYYDALVSREVLDLCRRDADKVFVGKKRSNHAVAQQGINQLMIDAASSGKRVVRLKGGDPFVF... | Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yie... | A5WEG6 |
Q57HU2 | ILVC_SALCH | Ketol-acid reductoisomerase type II | Salmonella | MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADW... | Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu... | Q57HU2 |
J7FIP8 | IDTP_CLAPA | Indole-diterpene biosynthesis cluster protein P | Claviceps | MFLLHILAIGACLLWYFVRSDKRKQGSNIPTIRRWPALFPEFLDRLSYNSCAARLVENGYREHKDRPFRLLKMDMDLVVIPLKYAQEMRALTSDELDPLTAVFDDNVGKVTGILLDSQLHTHAIQRRLTPRLPNIIPAMMDELNYAFQQVIPSEAGERLQTSWVPINPYDMVLELSTRAAARLFVGEPICRDEVFLKTSAAYSRNIFDTIHVSRSLGHIITPYLGSLIPSVRQFHQQFEYIQNLVLGEIAHRKQHSEDNKADDFLQWCMELARTKEESTPTALAQRTVGILSMAVVHTSAMATTHLLFDMISNQELREQL... | Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of paspalitrems, indole-diterpene (IDT) mycotoxins that are potent tremorgens in mammals . The geranylgeranyl diphosphate (GGPP) synthase idtG is proposed to catalyze the first step in IDT biosynthesis via catalysis of a series of it... | J7FIP8 |
Q46M05 | NDHK_PROMT | NDH-1 subunit K | Prochlorococcus | MELNPLKKSPSSEAVRNLREASCGPVGTPTVTNDLSENIILTSLEDLHNWARLSSLWPLLYGTACCFIEFAALIGSRFDFDRFGLVPRSSPRQADLLIVAGTVTMKMAPALVRLYEQMPDPKYVIAMGACTITGGMFSADSTTAVRGVDKLIPVDLYLPGCPPRPEAIFDAVIKLRKKVANESISERSKITQTHRYLTIPHKMKRVESKVNGQYLKAKTQLIALNPSLSEEFDQSLKEVQKISEELSSN | NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus co... | Q46M05 |
B1JJK2 | THIG_YERPY | Thiazole synthase | Yersinia | MLKIADTTFTSRLFTGTGKFSSPELMLEALRASGSQLITMAMKRVDLQSGNDAILAPLRQLGVRLLPNTSGAKTAEEAIFAARLAREALNTHWVKLEIHPDVRYLLPDPIETLKAAEVLVKEGFVVLPYCGADPVLCKRLEEVGCAAVMPLGSPIGSNLGLRTRDFLQIIIEQSKVPVVVDAGIGAPSHALEALELGADAVLVNTAIAVAHSPVQMAHAFRLAVESGERARLAGLGASPFNPSQPDTLQLRATATSPLTGFLSQLEEQEHV | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | B1JJK2 |
Q8HXY2 | MCAT_MACFA | Solute carrier family 25 member 20 | Macaca | MADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGIRGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGIFTTGIMTPGERIKCLLQIQASSGETKYTGTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYEWVKNIFTPEGKRVSELSVPRVLVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIPDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLNWATPNL | Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism... | Q8HXY2 |
Q03497 | STE20_YEAST | Serine/threonine-protein kinase STE20 | Saccharomyces | MSNDPSAVSELPDKDSLDNGISNDNERAMGGNGDGGDGLRLPRTTGTLNVNALQKGTNAAHEAGGYKSMDPAKNAETTNDDDNNVVSLDDPIQFTRVSSSSVISGMSSSMSPHSNIDETKSLEAVTPNINTSNITPDHSADNTFSTINASESDHQFNDTLLSKLSLTDSTETIENNATVKHQQPVASSTVNSNKSSTDIRRATPVSTPVISKPSMTTTPRQINSASHSLSNPKHKQHKPKVKPSKPEAKSKPVSVKKSFPSKNPLKNSSPPKKQTEKSYYSSSSKKRKSGSNSGTLRMKDVFTSFVQNIKRNSQDDKRAS... | MAP4K component of the MAPK pathway required for the mating pheromone response, haploid invasive growth and diploid pseudohyphal development. Links the pheromone response G-protein beta gamma subunits to downstream signaling components. Needed for mating in haploid cells, induction of a mating-specific gene FUS1, induc... | Q03497 |
P14870 | T2F1_PLAOK | Type-2 restriction enzyme FokI | Planomicrobium | MVSKIRTFGWVQNPGKFENLKRVVQVFDRNSKVHNEVKNIKIPTLVKESKIQKELVAIMNQHDLIYTYKELVGTGTSIRSEAPCDAIIQATIADQGNKKGYIDNWSSDGFLRWAHALGFIEYINKSDSFVITDVGLAYSKSADGSAIEKEILIEAISSYPPAIRILTLLEDGQHLTKFDLGKNLGFSGESGFTSLPEGILLDTLANAMPKDKGEIRNNWEGSSDKYARMIGGWLDKLGLVKQGKKEFIIPTLGKPDNKEFISHAFKITGEGLKVLRRAKGSTKFTRVPKRVYWEMLATNLTDKEYVRTRRALILEILIKA... | An S subtype restriction enzyme that recognizes the asymmetric double-stranded sequence 5'-GGATG-3' and cleaves respectively 14 bases after G-1 (top strand) and 13 bases before C-1 (bottom strand). | P14870 |
Q5E866 | APAH_ALIF1 | Diadenosine tetraphosphatase | Aliivibrio | MATYFVGDIQGCLDELLLLLERVEFNREKDQLWLTGDLVARGPKSLETLRFVKSLGNAAVTILGNHDLHLLAVSQGISRVKEKDKTAPIFTAPDSEELLTWLRHQPLLAVHSEYDIVMTHAGISPQWNMATAIDCAREVESVLLSDKWVLLLENMYENYPDTWDVTLSGIDRYRYIINAFTRMRFCHLDGRLDMECKLPPQDINSDELVPWFELENRLPLSHKVIFGHWAALMGHDGNNVIALDTGCVWGEYMTMYRVDDGKYFTQKAIEQ | Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. | Q5E866 |
O28278 | KAD6_ARCFU | ATP-AMP transphosphorylase | Archaeoglobus | MLIALTGTPGTGKSSVAERLRERGYKVATVVELAEKHGCIIDEEDGEIVIDVESLAARIDFEGIVEGHLSHLLKPDVAIVLRCNPAVLRERLKGRNWSEEKLLENLEAEMLDVILVEALEHASEVYEIDTTEMSLEEVIEAVEAIIRGDREARKRYKPGGIDWLSELEDRIEEFMRKV | Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. | O28278 |
B5FQM6 | ACEK_SALDC | Isocitrate dehydrogenase kinase/phosphatase | Salmonella | MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWETLLMRILSDLPLRLPWQNKSRDIRYIIAHLTETLGEDALPCCHVQVANELFYRNKAAWLVGKLTTPDGTLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRG... | Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully activ... | B5FQM6 |
Q8SPZ5 | RNAS8_AOTTR | Ribonuclease 8 | Aotus | MAPAREGCCPLLLLLLLGLWVAEIPVSAKPEGMTSSQWFNTQHVQPSPQACDSAMRDINKHTKRCKDLNTFLHKPFSSVAATCQTPNITCKNGHKNCHQSHRPVSLTMCGLTSGKYPNCRYKEEHQNKSYVVACEPPQQGDPEHSLVPVHFDKVV | Has a low ribonuclease activity. | Q8SPZ5 |
O67241 | FLIF_AQUAE | Flagellar M-ring protein | Aquifex | MDKLREYLNLLKERFNALTPVQKALAVGIPLLLLSLGAVALIYLSQENYTVLYTGLSPDDLNAVVTELDKEGVKYKISPDGRTIYVPENVARELRLKLAAKGVPRKGIVGYELFDKSGIVLSRFQQLVNFKRAIEGELAKTIMSLDCVEFARVHIVLPEKSLFIREEEEAKASVFLKLKPGCELTPEQVKAIRNLVSGSVENLKPSQVVVVDDKGRDLTAYLDEEFKTNASQLKVKREFEKSLERKLQKTLEEVFGYGKVKVNVSAELDFSSMKKREELYDPDLTAVVSEQKKKERTTSTRAQGIPGTQANIPPATGRQG... | The M ring may be actively involved in energy transduction. | O67241 |
Q9FX32 | SUS6_ARATH | Sucrose-UDP glucosyltransferase 6 | Arabidopsis | MSSSSQAMLQKSDSIAEKMPDALKQSRYHMKRCFASFVGGGKKLMKREHLMNEIEKCIEDSRERSKILEGLFGYILTCTQEAAVVPPFVALAARPNPGFWEYVKVNSGDLTVDEITATDYLKLKESVFDESWSKDENALEIDFGAIDFTSPRLSLSSSIGKGADYISKFISSKLGGKSDKLEPLLNYLLRLNHHGENLMINDDLNTVAKLQKSLMLAVIVVSTYSKHTPYETFAQRLKEMGFEKGWGDTAERVKETMIILSEVLEAPDNGKLDLLFSRLPTVFNVVIFSVHGYFGQQDVLGLPDTGGQVVYILDQVRALE... | Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. | Q9FX32 |
Q3BVL0 | DXR_XANC5 | 2-C-methyl-D-erythritol 4-phosphate synthase | Xanthomonas | MAGSSLRQVAVFGATGSIGASALDVIARHPERLRASLLSAGSKVDELLALCATHRPAHAVIADAALYPALRDGLRALGLATQAHAGAEALDALASGDVCDTVVAAIVGAAGLPSTLAAARAGKRLLLANKESLVLAGELLTRTAAAAGAEIIPIDSEHSAIFQCLRSCDASRGVRRVILTASGGPFRGRDRAALAAVTPAQAVAHPKWSMGPKISVDSATMMNKGLEVIEAHHLFGLPGEQIDVLVHPQSLVHSLVEFVDGSTLAQLGLPDMRTTLAVGLAWPERVDSGVGGLDLLRQGRLDFEAPDTAAFPCLRLAWDA... | Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). | Q3BVL0 |
A2SU08 | DHQS_METLZ | 3-dehydroquinate synthase II | Methanocorpusculum | MTIQLPPILIRADHLQTYDERKAIVASALESGYTHIILRPEDEALRHLGRYTAILADGKNLMYSGERIGVLLNLTGAEEMEEAYSLKNAVPNLIISPENWKVIPLENLISRFQNAETSVYICVKTPEEARLAFQTMEVGCDGIVITPDGPADLAAFSGIRNDEYPIVDLETAVVTKISTLSLGDRVCIDTCSLLERGEGMLIGSQSSCLFLVCSESFESEYVNSRPFRVNAGAVHSYILCPDGTTKYLSEIASGNELLSRMPDGNLRTVNVGRVKIEIRPMLYIEAKAGGKTYSVVLQNAETIRLGTPSGAVSVSDLAIG... | Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis. | A2SU08 |
Q1QDH2 | RS8_PSYCK | 30S ribosomal protein S8 | Psychrobacter | MSMQDTVGDMLTRIRNAQMANKVSVAMPNSKLRKSIADLLVNEGYVASAVVTEENNNKATLTIVLKYFEGKAVIETIQRFSRPGLRQHRGKDAIPTVKQGMGVAIVSTSQGIMTDRAARAAGIGGEVVAFVA | One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit. | Q1QDH2 |
Q8FVV5 | FBPC_BRUSU | Fe(3+) ions import ATP-binding protein FbpC | Brucella | MTAIRPGSVTFENVTKKFGNFTALPNLSLTVEPGTLVTLLGPSGCGKTTTLRLLAGLEHPTSGRILVGGKDVTNLPANERDVSMVFQSYALFPHMTSLENVAYGLESSGFKKNEARERAEEGLKLVGLGGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSNLDARLRRRVRTEIRELQQRLGFTADYVTHDQDEALAVSDTIIVMKEGGIAQKGSPRDLYEAPASAFIADFMGEANVVPCEVISAENGEAVIRVAGLTHRVPARNAQPRPAQLAIRPNAVTLQPQAGGGFSGTVAHSAYLGDHIEYEIETEHG... | Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. | Q8FVV5 |
A7FR60 | PANB_CLOB1 | Ketopantoate hydroxymethyltransferase | Clostridium | MRNTVSTFQELKNKGEKITMLTAYDYSMAKLIDSSGINGILVGDSLGMVCLGYENTLSVTMEDMLHHTKAVVRGTSNALVVGDMPFMSYQTSIYDAVYNAGRFIKEAGAHAVKLEGGATVAEEIKAIVKAQIPVMGHIGLTPQSVNMFGGFKVQGKNEKVAKKLIEDAKILEEAGAFSIVLECIPEKLSKIISESISIPTIGIGAGKYCDGQILVYQDMLSMFSDFKPKFVKSFGNIGESIKDGVSQYIKEVKEVKFPEEKHAFKIDDDVINKLY | Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate. | A7FR60 |
Q9HIS1 | RS14Z_THEAC | 30S ribosomal protein S14 type Z | Thermoplasma | MSQVKLKPKKKYGHIDGCVRCGRKRGIVRRYGLHLCRQCFRETARQLGFEKYS | Binds 16S rRNA, required for the assembly of 30S particles. | Q9HIS1 |
Q4Z4D2 | PF36P_PLABA | Sporozoite surface protein Pbs36p | Plasmodium (Vinckeia) | MKRRRIFMYYCFCFLLKYVAFSNVTNPNTTLGHFEICKINIYSGDAEECVLENEFGKMFLFICDIDYNEMSKNIVLPSECAKKTYIDHVNPNGTSPEVNTYDIFPDLIGANESKFRDKFYFYGTPYSSKDIDFICLCFSEVKPDIKHIIKMSFKKMTKKIKGCDFGDNVPTKKDLTNGKALYENSSCHIYAYPGDVIGINCYKKDINNIYNNNLELSPNNCFHNVYYENDILLSSKNLIPNSRVIPDPSNDVKLSKMHSYMSYIILPDEINENVKISCSCKRNEYVGTMFLYVNTSKNILTYTGNNSIISNHANKKYYEH... | Involved in sporozoite infection of hepatocytes and replication therein. | Q4Z4D2 |
B4QS37 | EI3G2_DROSI | Eukaryotic translation initiation factor 3 subunit 4-2 | Sophophora | MKSFITSWADEVDADYVDGLPPSNEYIKGDYKYVTEYKFNDDGKKVKVVRTFKIEKQIVPKAVARRRNWVKFGDSRSDKPGPNSQTTMASEEILMQFIGSKEFDQTHETQLDPGKNIAKCRICNGEHWSVNCPYKGTSMDSKTMMETKANAAAAAAISDPSKTGKYVPPFMKDGGGISGSKNWGRGRDRDDSSAVRISNLSESMTETDLEELVKKIGPHTKMYLAREKNSGLCKGFAYVHFKFRQDAAAAIEVLNGHGYDHLILCVEWSKPQP | RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and... | B4QS37 |
Q6LRA1 | ZAPC_PHOPR | Cell division protein ZapC | Photobacterium | MLKPNNSWMWYFDLKDNSLMLDLGSDMVFRVGIPAKHLIPSASEQCEFTVDDASIFQNYKENVSHLEISEPRKAELALNAVAASRFHKPMMPKSWFFDTQSVSCDPENSDIVTLQTPLGMAKFIVIENSGCASLCMMVDVEPLALSSTKEIRFCDTIKVMNNRITAYEEDAILNLALVG | Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | Q6LRA1 |
B2JIA0 | GUAA_PARP8 | Glutamine amidotransferase | Paraburkholderia | MHDKILILDFGSQVTQLIARRIREAHVLSEIHPHDVSDEFIRDFKPTGIILSGGPNSVTETDTPRAPQAVFEAGVPVLGICYGMQTMAEQLGGKVDSGHLREFGYAEVRARNHTSFLDGIQDFATPEGHGMLKVWMSHGDKVLEMPQGFQLMASTESCPIAAMADETRHFYGVQWHPEVTHTVQGRAMLERFVLKICGAKPDWEMGNYIDEAVENIRKQVGDEHVILGLSGGVDSSVAAALLHRAIGDQLTCVFVDHGLLRLNEAEQVMSMFADNLGVKVIHVDASEAFMSKLKGVTDPEAKRKIIGAEFVEVFQTEAGK... | Catalyzes the synthesis of GMP from XMP. | B2JIA0 |
Q4J9D4 | TREH2_SULAC | SaTreH2 | Sulfolobus | MNYALLSNGITTALEKEGSIEWFPVPKFDSPSVFTKILDEDKGGYFLITPEKFNKVKQQYVEYSLILRTEFDDGNLILIDFLPLSLPAIIRLYEAKVPFNVEVKPLFNYGLVNAGTETRKDGIIYKNPESKEGLELLINGDYKIISPYRITVNSGKGYLYLLYSRDLRYGLFSQKGFVYSEPYEAYSKLLYYSRKELERARKPSIYENAFYRSLSVILGLIYKPSGGIIASPTTSIPEIVGDERNWDYRYVWVRDSSYAIEALVKANLLTHARRALDFLTNLLDPSSKSFDHPFYSVDGTPPPAEENLDWLSGFMNSKPV... | Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose. | Q4J9D4 |
Q5XI97 | AASD1_RAT | Alanyl-tRNA synthetase domain-containing protein 1 | Rattus | MAFLCQRDSYAREFTTTVVSCCPAELQTDGNGSKKEVLSGFQVVLEDTLLFPEGGGQPDDRGTINDISVLRVTRRGAQADHFTQTPLSPGSQVQVRVDWERRFDHMQQHSGQHLITAVADLLFGLKTTSWELGKLRCVIELDSPSVTAEQVAAIEQSVNQKIRDRLPVSVRELSLDDPEVEQVRGRGLPDDHAGPIRVVTIEGVDSNMCCGTHVNNLSDLQVIKILGTEKGKKNKSNLIFLAGNRVLKWMERSHGSEKALTSLLKCGAEDHVEAVKKLQNATKLLQKNNLNLLRDLAVHTAHTLRSSPAWGGVVTLHRKE... | Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). | Q5XI97 |
P83915 | TX21_PHOKE | Neurotoxin PKTx21C2 variant Ala-1 Del | Phoneutria | AFCKYNGEQCTSDGQCCNGRCRTAFMGKICMG | May act as a neurotoxin. | P83915 |
Q9S2X2 | SEPF2_STRCO | Cell division protein SepF 2 | Streptomyces albidoflavus group | MAGAMRKMAVYLGLVEDDGYDGRGFDPDDDFEPELDPEPERDHRRHEPAHQSHGAHQSQRDEEVRVVQPPAQREPMPRAASLAAESSRPARIAPVASITQERASLEKSAPVIMPKVVSEREPYRITTLHPRTYNEARTIGEHFREGTPVIMNLTEMDDTDAKRLVDFAAGLVFGLHGSIERVTQKVFLLSPANVDVTAEDKARIAEGGFFNQS | Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Q9S2X2 |
B5QZ36 | HLDE_SALEP | D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase | Salmonella | MKVNLPAFERAGVMVVGDVMLDRYWYGPTCRISPEAPVPVVKVNTVEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKTLAEVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALGSIGALVLSDYAKGALTSVQTMISLARQAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKSEDELVERGMKLIADYDLSALLVTRSEQGMTLLQPNKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNTLEEACYFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGF... | Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | B5QZ36 |
A4G738 | PYRG_HERAR | UTP--ammonia ligase | Herminiimonas | MTKFVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFITAKMRKVNNFTTGQIYESVIRKERRGEYLGKTVQVIPHITNEIQDYIYRGAEGFDVALVEIGGTVGDIESLPFLEAARQLSLRAGRNAAAFVHLTLVPYLVSAGELKTKPTQHSVQKLREIGISPDALLCRADRPIPDDERAKISLFSNVPEDAVISVWDADTIYKIPQMLYDQGLDRIVCEKLALSPKPADLSVWTKLVHALENPKHSVTIGMVGKYVDLTESYKSLTEALRHAGIHTES... | Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | A4G738 |
P9WNV3 | LIGD_MYCTU | Polydeoxyribonucleotide synthase [ATP] | Mycobacterium tuberculosis complex | MGSASEQRVTLTNADKVLYPATGTTKSDIFDYYAGVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHRSGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPGSGELNPGPATRLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHLYTPLDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWSQNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIARDGDLLERLDADAPVADRLTRYRRMRDASKTPEPIPTAKPVT... | In conjunction with endogenous or Mycobacterium phage Omega Ku (AC Q853W0) can reconstitute NHEJ in Saccharomyces cerevisiae. | P9WNV3 |
Q61212 | NPY6R_MOUSE | Pancreatic polypeptide receptor 2 | Mus | MEVLTNQPTPNKTSGKSNNSAFFYFESCQPPFLAILLLLIAYTVILIMGIFGNLSLIIIIFKKQREAQNVTNILIANLSLSDILVCVMCIPFTVIYTLMDHWVFGNTMCKLTSYVQSVSVSVSIFSLVLIAIERYQLIVNPRGWKPRVAHAYWGIILIWLISLTLSIPLFLSYHLTNEPFHNLSLPTDIYTHQVACVEIWPSKLNQLLFSTSLFMLQYFVPLGFILICYLKIVLCLRKRTRQVDRRKENKSRLNENKRVNVMLISIVVTFGACWLPLNIFNVIFDWYHEMLMSCHHDLVFVVCHLIAMVSTCINPLFYGF... | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY = PYY >= NPY (2-36) = [Leu-31, Pro-34] NPY > NPY (13-36) > PP. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity. | Q61212 |
P36266 | NUSG_STRCO | Transcription termination/antitermination protein NusG | Streptomyces albidoflavus group | MSDPNVNDAIEPVESVEDELGTVEGADNEDTEASAEAEAADDTVVAETDEDATDAEADETAEATDAEATEAEADADADAAEAEESEEEPEAEEPELDPIEKLRQELRVLPGEWYVIHTYAGYENRVKTNLEQRAVSLNVEDYIFQAEVPQEEVVQIKNGDRKTIRQNKLPGYVLVRMDLTNESWGVVRNTPGVTGFVGNAYDPYPLTLDEIVKMLAPEAEEKAAREAAEAEGKPAPQRKVEVQVLDFEVGDSVTVTDGPFATLQATINEINADSKKVKGLVEIFGRETPVELSFDQIQKN | Participates in transcription elongation, termination and antitermination. | P36266 |
P31430 | DPEP1_RAT | null | Rattus | MLIIWWFWSLLAICASDSFRNQAENIMRTTPVIDGHNDLPWQMLTLFNNQLRKSEANLSALAETHTNIPKLRAGFVGGQFWSAYMPCDTQNKDAVKRILEQIDVIHRMCQLYPETFECVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDKGDDEAESQGLSPFGKLVLNEMNRLGVMIDLSHVSVATMKDALQLSKAPVIFSHSSAYSVCPHRRNVPDDVLQLVKSTNSLVMVNFYNQFVSCSDSATLSQVADHLDHIKKVAGAGAVGLGGDYDGVTNLPVGLEDVSK... | Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver. | P31430 |
A1SZY2 | HLDE_PSYIN | D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase | Psychromonas | MKITLPEYDKAQVLVVGDVMLDRYWHGPTARISPEAPVPVVKVEQIEERPGGAANVALNVAALGGKVNLIGLVGDDEAANVLVKNLKSVHVNTDFVSVPNFPTITKLRVLSRHQQLLRLDFEEGFEGIDSTDILEKMHASLTRQPSVVILSDYNKGSLADVQKMIQLAKKFNSVVLVDPKGSEFEKYRGATLLTPNLAEFEAVVGKCHSEKELVERGLALIKELDLDALLVTRSEHGMTLLREGQEPLHLPTQAQEVYDVTGAGDTVISVLASSLAAGSSFEQACTLANAAAGVVVGKIGTSTVNTIELANAVYSQQEIG... | Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | A1SZY2 |
D4GYH2 | AGLI_HALVD | Archaeal glycosylation protein I | Haloferax | MADSPFPCVSVIVPVYNDPTGIRDTLTALTKQTYPTERVNILPIDNGSTDETRDVIRQFEREHENVTLVVEDEIQGSYAARNTGIEQATGEIFAFVDADMYMDESWLETAVDAMDEAAYVGCDIELVTNGEDTLPARFDAQTAFPIAQYIRQQQYAPTCGLLVSREVVDDVGPFDERLVSGGDSEFGSRVANAGYRQAFAPAATLYHPVRDSFSSLVKKELRVGRGLCQRQEYYADRFGRPGIPPRPSGVKSPDEESSGLDFERLLFGVLSVVMTGVRALGYYREYVRYVRGNTR | Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Catalyzes the addition to the dolichol phosphate carrier of the hexuronic acid found at position 3 of the pentasaccharide. | D4GYH2 |
A6U9C1 | GLMU_SINMW | Glucosamine-1-phosphate N-acetyltransferase | Sinorhizobium | MERTCLAIILAAGESTRMKSAMSKVLHPVAGRAMISHVVDALASASISDVALVVGRDAEAVAAAANTGDVAVTALLQKERLGTAHAVLAAREAIAKGYDDILVVFGDTPLITAAPLEAARDGLAAGNDVVVIGFQAADPTGYGRLIVEGDALVAIREHRDASEEERRITYCNGGLMAIDGRKALDLLDRVGNTNAKGEYYLTDLVEIVRSLGGRAIAVEAPEEELTGCNTRAELAYIERLWQQRRRHELMLAGVSMVAPETVFLSWDTALAQDVLVEPNVVFGPGVRVESGAIIHAFSHLEGAHVRAGAAVGPFARLRTG... | Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ... | A6U9C1 |
Q9V0N5 | DHYS_PYRAB | Probable deoxyhypusine synthase | Pyrococcus | MKAKDIVLKKSEEIEGLAIEGPWLDEVESLEGVISYYEKIGFQATHLGKAVKIWRKVEEKRKGGEEVRVFLGYTSNIVSSGLREIIAWLVKERKVDVIVTTAGGIEEDFIKTLKPFILGDWEVNDAELREKGINRIGNIFVPNDRYIEFEKYMVPFFERILDIERKLKRPLTASEFIYEMGRYMDEVLGKEKEKSIIYWAYKRDVPIFCPAITDGSIGDMLYFFKEERHDSKLVIDIANDIVKLNNLAITAKETASIILGGSLPKHAIINANLFRGGTDYAIYISTAVPWDGSLSGAPPSEGVSWGKIKAKADYVEIWAD... | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Q9V0N5 |
Q6FKP2 | PAN3_CANGA | Poly(A)-nuclease deadenylation complex subunit 3 | Nakaseomyces/Candida clade | MDKINPDWARDVPCRNVIIYGFCKKKTEGCPFKHDDDDIATPTSTPKVADTVPAPSGVIQQPSKISVSSLPSLNSQPSSTAPTSAPNATAHTGSKSQVPKFNAKASASFTPMSKAADGTQETQAPYLESPVAGSPGPILKAGTPVSFMQPNIYSTTPVPSPASMAMPNVVMPPNDMGSPDLGLQQQSHMVNLDGSIQQNYQERPNVLMRDSSMPLTMGTSGSRPMLDQQIHSISGLSNTSGPQPPGLLQSMNGASMDMGLPMNLRYPTIYPPTHSILQYHLYAPDPPPQLEIALKENERTPRMLFIPNDLREELVKRNLA... | Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened m... | Q6FKP2 |
P22705 | RPOC2_NOSS1 | Transcriptase subunit beta' | Nostoc | MTNEKMIFRNRVVDKGQLRNLISWAFTHYGTARTAVMADKLKDLGFRYATRAGVSISVDDLMVPPSKRSLLEAAEEEIRATEVRYQRGEITEVERFQKVIDTWNGTSEALKDEVVTHFKQTNPLNSVYMMAFSGARGNISQVRQLVGMRGLMADPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIIREIDCGTTRGIPVRPMTEGSKTLIKLSTRLLGRVVGEDVIHPKTKEVIAPRNTPISDDLAKEIEKAGVAEVVVRSPLTCEAARSVCQHCYGWSLAHAKMVDLGEAV... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | P22705 |
B3EK98 | NUOD_CHLPB | NDH-1 subunit D | Chlorobium | MQELGKAEHTSIRVTPQGENRVIVEKDLSSEEMILNMGPQHPSTHGVLRLECKTDGEVVIEAEPYLGYLHRCFEKHAEMVDYPGIVPFVDRMDYLASMNNDFAYCIAVEKLLDIEIPRRVEFMRVIVSEINRIASHLVAIGTYAIDLGAFTPFLFCFRDREHMLNLLEWTSGARMLYNYILIGGVAYDFPKDFARRTLEFVKYFRPKALELQKLLTENEIFVKRTKGVGMMPADVAINYGWSGPMLRGSGVEWDLRRVDGYSVYPELDFKVCVPDGKFSDIGDSLSRHVVRALEIEESLNIIEQCLDKMPEEEGFDPRSA... | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions ar... | B3EK98 |
A5GPF9 | SYA_SYNPW | Alanyl-tRNA synthetase | unclassified Synechococcus | MAVARSSRTDAARPRTGAEIRDAFLAFFEERGHKRMPSASLVPEDPTVLLTIAGMLPFKPIFLGQQERPAPCATSSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKQQAIEWAWELSTGVFGLDPKNLVVSVFRDDDEAEQIWREVVGVNPKRIIRMDEEDNFWASGPTGPCGPCSEIYYDFKPELGDDGIDLEDDDRFIEFYNLVFMQSNRDAEGTLTPLANRNIDTGMGLERMAQILQKVPNNYETDLIFPLIQAAAERAGVDYHQLDEKGKTSLKVIGDHSRAVTQLISDGVTASNLGRGYILRRLLRRVVR... | Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | A5GPF9 |
Q60948 | MAD4_MOUSE | Max-interacting transcriptional repressor MAD4 | Mus | MELNSLLLLLEAAEYLERRDREAEHGYASMLPFDGDFARKKTKTAGLVRKGPNNRSSHNELEKHRRAKLRLYLEQLKQLGPLGPDSTRHTTLSLLKRAKMHIKKLEEQDRRALSIKEQLQREHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSAGSSSDADDHYSLQSSGCSDSSYGHPCRRPGCPGLS | Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. | Q60948 |
B8E4W4 | LIPA_SHEB2 | Sulfur insertion protein LipA | Shewanella | MNRPERLQPGVKLRDADKVSRIPVKIVPSERDTMLRKPDWLRVKLPASNQRILEIKQALRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLKPDAEEPVKLAQTIRDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRKLNPDIKIETLVPDFRGRIDAALDILSTEPPDVFNHNLETAPMHYRKARPGANYQWSLDLLKRFKERHPNVPTKSGLMMGLGETNEEIAQVLRDLRAHNVEMLTLGQYLQPSKFHLPVERYVPPAEFDELKALADELGFTHAACGPLVRSSYHADLQAQGKEV... | Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | B8E4W4 |
Q0AK66 | RBFA_MARMM | Ribosome-binding factor A | Maricaulis | MARRQTHTSKGPSQRQLRAGELVRHALVGIIAREEFRDPDLEGQMISVTEVRPSPDLRVAKVYVAPLGRGDSAKLAAGLNRCAAFLRGRLGREIEMKFTPELHFHADNSFDTASHVDDLLNRPTVRKDLDATRGSEADAED | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli... | Q0AK66 |
P66920 | THIE2_STRPN | Thiamine-phosphate pyrophosphorylase 2 | Streptococcus | MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNLTTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGPEKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPVVAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLKKLHNILS | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | P66920 |
B0TF85 | DTD_HELMI | Gly-tRNA(Ala) deacylase | Heliomicrobium | MRALIQRVLRGRVTVEGSEVGAIGPGLVVLVGAGQGDGEADARYVAEKIAHLRIFEDEQGKMNRSVSDVGGEVLVVSQFTLYGDCRKGRRPSFTQAAPPDEARRLVEAVVAELRKFGLTVATGQFQAHMVVEIINDGPVTLMVEGRGGES | An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By rec... | B0TF85 |
A3PEY3 | IF2_PROM0 | Translation initiation factor IF-2 | Prochlorococcus | MTISDKIRIYELSRDLNLENKDILDAAQKLSISVKSHSSSISAEEAKKIKNLINKKNSDKKILSINKPSIKKDNFKQNKSPSISSKKETPLKDNSNKKPLLIKPLNKPESVKIISNQLQNSNKPNIVNTSQSRANLTNTNINSKTSQNLNQDKKTFENNITPPIKSPAKPPIQLIAKPKNINNNVKSNESSQNISSAGDNRRLSNKPDQNTNKPKTKNYDSKIKTPELVGAPIRREDPKINPNKQNNKQNIAFKQTGSNRIGSPNRPGMPNNRPGLRNKPSDQGRPGSFNRQGNPNRPGMPNNRPGLRNKPSDQGRHGSF... | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. | A3PEY3 |
B0USH2 | PROA_HISS2 | Glutamyl-gamma-semialdehyde dehydrogenase | Histophilus | MSLKEMGKNAKQAATILAQLSQQQKNTALQIIAEQLELQSDKILVENAKDIQLAKENGLSDAIIDRLLLTKERINSIAKDVRHIISLSDPIGQIIDGGILESGTKLERVRVPLGVIGVIYEARPNVTVDVATLCLKTSNAVILRGGKETNYSNKILVKVIQDALEQTGLPKNAVQAITDPDRNFVLELLKLDKYVDMIIPRGGAGLHEFCKQNSTIPVIIGGVGVCHVFVEESAEQDKALAVIDNAKTQRPSTCNTLETLLVQESIATEFLPKLVAHLKHKNVKYHADPTALSILEKQNAEVSIVQEQQLRQEWGSLDLN... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. | B0USH2 |
A5VNW2 | ATP6_BRUO2 | F-ATPase subunit 6 | Brucella | MANDPIHQFQVSRWIPIDVGGVDLSFTNVSAFMVATVVLASGFLYLTSSGRGLIPTRLQSVSEMAYEFVATSLRDSAGSKGMKFFPFVFSLFMFVLVANFIGLFPYFYTVTSQIIVTFALSLLVIGTVIFYGFFKHGFGFLKLFVPSGVPGIIVPLVVLIEIISFLSRPISLSVRLFANMLAGHITLKVFAGFVVSLSSLGALGIGGTVLPLLMTVAITALEFLVAFLQAYVFTVLTCMYINDAVHPGH | Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | A5VNW2 |
A3PF25 | RPOA_PROM0 | Transcriptase subunit alpha | Prochlorococcus | MLQYQIERIDHQIADDRSQTGTFLIGPLERGQATTLGNSLRRVLMGGLEGSAVTAVRIAGINHEYATIPGVREDVLDILLNCKQLSINSTNPELEIGRLVASGPMEVKANDIQFSSQVEIVDGEKPIATIQEGHNLELEIHVERGVGYRPVDRKSEETTAIDLLQIDAVFMPVKRVNFTIDETAVAEGGTGRERLKMEVVTDGSTSPDDAIAEAANQLIELFQPLATVTMVEEIPEEPEPSPEAQIPLEELNLSVRAYNCLKRAQVNSVSDLMGFSYEDLLEIKNFGSKSADEVIEALERIGISIPQSRTSV | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | A3PF25 |
B0TQP2 | LPXC_SHEHH | UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase | Shewanella | MIFQRTVKEMVKTTGVGLHSGNKVTLTIKPAPVNTGIKLVRTDLSPAVEIPAVADQVRETTMCTALVNDDGVRISTIEHLFAALAGLGIDNAVIEVDAPEIPIMDGSASPFVFLLQSVGIQEQSAAKKYIKITKPIRVEDGDKWAELKPFKGFRVDFAIDFNHPEIARSQQHMVMDFSSSAFIKDISRARTFGFMRDIEYLRANNLALGGSMENAVVLDEYRVLNPDGLRYEDEFVKHKILDAFGDLYVAGHAIVGEFCAFKTGHALNNQLVRAMLAQQDAWEIVSFEKEADAPVSFSVPAGAVFA | Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | B0TQP2 |
B4U0X9 | RS14_STREM | 30S ribosomal protein S14 | Streptococcus | MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSNPNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW | Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | B4U0X9 |
A7ZNW5 | CDD_ECO24 | Cytidine aminohydrolase | Escherichia | MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAENADAPLIQWDATSATLKALGCHSIDRVLLA | This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | A7ZNW5 |
P15925 | FPGS_LACCA | Tetrahydrofolylpolyglutamate synthase | Lacticaseibacillus | MNYTETVAYIHSFPRLAKTGDHRRILTLLHALGNPQQQGRYIHVTGTNGKGSAANAIAHVLEASGLTVGLYTSPFIMRFNERIMIDHEPIPDAALVNAVAFVRAALERLQQQQADFNVTEFEFITALGYWYFRQRQVDVAVIEVGIGGDTDSTNVITPVVSVLTEVALDHQKLLGHTITAIAKHKAGIIKRGIPVVTGNLVPDAAAVVAAKVATTGSQWLRFDRDFSVPKAKLHGWGQRFTYEDQDGRISDLEVPLVGDYQQRNMAIAIQTAKVYAKQTEWPLTPQNIRQGLAASHWPARLEKISDTPLIVIDGAHNPDG... | Involved in the conversion of folates to polyglutamate derivatives, and likely functions in the retention of cellular folate pools. Catalyzes successive MgATP-dependent additions of glutamate to a pteroylmonoglutamate substrate, with a high preference for 5,10-methylenetetrahydrofolate (mTHF). Thus, metabolizes mTHF to... | P15925 |
A1ASB3 | PYRDB_PELPD | Orotate reductase (NADH) | Pelobacter | MKPDMTVNLAGLELRNPVMTASGTFGYGREFADYVDLEKIGAFVTKGLSLKPRPGNPTPRIVETPGGMLNAIGLQNVGIEAFIAEKVPFLARVNTPAIVNFFGSTPEEYAELAGRLDEIPQVAGLEVNISCPNVKQGGIVFGTDPACAGQVVAACRRATKKPLIVKLSPNVTDVVVMAQACADAGADALSLINTLTGMAIDLKSRKPVLANITGGLSGPAIKPVALRMVWQVSRAVQVPLIGIGGITSATDALEFILAGASAVQVGTASFITPSASQEIAQGMERWLEEHGVARVSDLVGALEC | Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor. | A1ASB3 |
Q2L1H6 | UBIC_BORA1 | Probable chorismate pyruvate-lyase | Bordetella | MTTKYQAPLAAGWLIRAPSLLSPTQRHWLFRPGALTAGLRQLGKVQLRVVSEHAEGASLDEARAMLIAPGSPVWVREVLMSVDGIDSVPARSLTPLAASHGSWQGMRRLLTRPLADMLYHDRGVTRSPFVCRRLSSPLPFYRMALPPNHDGSAIWARRSVFWRHGQPLLVAECFLPDFWRKVTLGRAIPPLKAHDRRA | Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. | Q2L1H6 |
P10054 | RL1_PROVU | 50S ribosomal protein L1 | Proteus | MAKLTKRMRNIREKVEVTKQYEIAEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFAQGANAEAAKEAGAELVGMDDLAAKVKAGEMDFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVVSTKHKLKENLEALLVALKKAKPSAAKGVYIKKVSLSTTMGAGVAIDQASLSATV | Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. | P10054 |
Q8M893 | NU1M_EMBAL | NADH dehydrogenase subunit 1 | Emballonura | MFLVNLLLMIIPILLAVAFLTLLERKTLGYMQLRKGPNIVGPHGLLQPIADAIKLFTKEPLRPLTSSTSMFIMAPILALSLALTMWTPLPMPYPLINMNLGVLFILAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFSLPNLSTTQENLWLIIPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAGGSFALFFLAEYANIIMMNAITTTLFLGLYQNPSLPEFYTTSFMIKTLLMTITFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVSIPILTASIPPQT | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I. | Q8M893 |
Q0UQV6 | BST1_PHANO | GPI inositol-deacylase | Parastagonospora | MVREKAQVTMGSTTMDMLEDEVVKAQDRRWRLRLRNPWACSAYTLVTTALGFAAFFLMLQSFLTKQLDTKGCEMVYMRPMYSKFDDFDTEHTRFASKYSLYLYREWGIDEEFTVKGAPVLFIPGNAGSYKQVRSLAAESAYHYHNSVQHESNAGKGERRPLDFFAVDFNEDFTAFHGQTVLDQAEYLNDAITFILSLYHTPGRSRRDPHLPDPTSVIIVGHSMGGVVARTLFTMPNYQANSINTIVTIAAPHARPPVSFDGDIVRTQNAVNSYWRSAYAQDSAKDNPLQHVTLVSIAGGGLDNIVSSDYASIASIVPETH... | Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. | Q0UQV6 |
A5IJ44 | COAD_THEP1 | Pantetheine-phosphate adenylyltransferase | Thermotoga | MKAVYPGSFDPITLGHVDIIKRALSIFDELVVLVTENPRKKCMFTLEERKKLIEEVLSDLSGVKVDVHHGLLVDYLKKHGIKVLVRGLRAVTDYEYELQMALANKKLYSDLETVFLIASEKFSFISSSLVKEVALYGGDVTEWVPPEVARALNEKLKEGKR | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. | A5IJ44 |
A0PZH1 | MINE_CLONN | Cell division topological specificity factor | Clostridium | MDLFKLFSGKPSSKEVAKDRLKLILIHDRSSIAPELLEVMKSDILKVISKYVIIDDDEVEVRLTKTEEVDASSPALIASIPIKKMKQR | Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | A0PZH1 |
Q889E3 | LSPA_PSESM | Signal peptidase II | Pseudomonas | MPDATLSNTSLGRLAWLWLTVLIVAVDQVSKYYFENALSLYQQIIVIPDYFSWTLAYNTGAAFSFLADGAGWQRWLFALIAVVVSAVLVVWLKRLGRDDTWLAIALALVLGGALGNLYDRVVLGHVIDFILVHWQNRWYFPAFNVADSAITVGAIMLALDMFKSKKTGETVND | This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | Q889E3 |
Q8WML3 | KAT6B_MACFA | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4 | Macaca | MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKSTKESRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPK... | Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. | Q8WML3 |
C1DCY1 | PLSY_LARHH | Lysophosphatidic acid synthase | Laribacter | MTTIASLVLAYLLGSVPFAVLVSLGMGLADPRSYGSGNPGATNVLRSGNKLAALLTLLGDAAKGWLAVWLAQTYGASFGLAAPEIAMVGLAVFIGHLWPVFLAFRGGKGVATALGVLLAVNPWLALIAAAVWLAVALLTRYSSLAAMVSAVATAVAAWFIEPGVYAGLTIVIALLLVRRHKQNILNLVSGTESRIGGKKKS | Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | C1DCY1 |
A8GB06 | CRCB_SERP5 | Putative fluoride ion transporter CrcB | Serratia | MLSSLLAVFIGGGMGSVLRWAISMKMNPLNAHIPLGTLAVNLLGGFIIGLAIAIFSRLTHLDPTWKLLITTGFCGGLTTFSTFSLEVVYLLQDGRFMWALANMLLNLAGSLVMTLLAFMLVVWINGQ | Important for reducing fluoride concentration in the cell, thus reducing its toxicity. | A8GB06 |
B8HA70 | MSRA_PSECP | Peptide-methionine (S)-S-oxide reductase | Pseudarthrobacter | MKTFVLGGGCFWCLDAVYQKTKGVTAVVSGYTGGHDPYPDYYSVCSGTTGHAEVVAVTFDEEIIPAEVILDMFFALHDPTTLNRQGYDVGTQYRSSMFYETTEEKILFEEAIDRNQALWSHPIVTEVSRLPRFHVAEEFHQDYYAKHPEQGYCQVIINPKLAKARKYYSAWLNA | Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | B8HA70 |
B2TQ14 | THIM_CLOBB | 4-methyl-5-beta-hydroxyethylthiazole kinase | Clostridium | MINEILDKVVRLLEEVRAKKPLVHSITNYITATDCANVILAVGGSPTMADYVKEVEEIASISSAVVLNMGVISDGMVESMILAGKSANKNNVPVIFDPVGAGVANFRNESAEKILSEVKIDIIRGNISEIKFICGLSSETKGVDASESDMNMGNDKKAIVAQELAKKLNCVVAITGVDDIISDGKRNVILSNGHKMLANVTGTGCMSSALCGAFAGASNDYFIAAICAILTMGISGEIAYEKSKGIGMGTFHTSLIDAISMMNENIIKEKAKVTTINR | Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). | B2TQ14 |
P28072 | PSB6_HUMAN | Proteasome subunit Y | Homo | MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA | Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participate... | P28072 |
Q5XE09 | G6PI_STRP6 | Phosphohexose isomerase | Streptococcus | MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKEEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYLGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQE... | Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate. | Q5XE09 |
Q6AC71 | DCDB_LEIXX | DCD-DUT | Leifsonia | MLLSDRDIKAELTAGRLGLEPFEQGMIQPSSVDVRLDRFFRLFDNHKYPFIDPAEDQPDLTRFVEVVADQPFILHPGEFVLGSTFELVSLPDDVAARLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNVATLPIKLWPGMKIGQMCFFRLSSAAEKPYGSAEYSSRYQGQRGPTASRSFLNFHRTDVSGTEAGRSSS | Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Q6AC71 |
A4F804 | ENO_SACEN | 2-phosphoglycerate dehydratase | Saccharopolyspora | MAIIEQVGAREILDSRGNPTVEVEVALEDGTLTRAAVPSGASTGEHEAVELRDGDAERYGGKGVEKAVEAVLDEIGPELAGVDAIEQRVVDQKLVDLDGTPDKSRLGANAILGVSLAVAKAAAESVGLELFRYVGGPNAHVLPVPMMNILNGGAHADTGVDVQEFMIAPIGADSFSEAVRWGAETYHSLKSVLKAKGLATGLGDEGGFAPDLPSNREALDLIASAIEKAGYKLGRDIVLALDVAATEFYRDGAYHFEGSKRSAEQMAGYYGELLDAYPLVSIEDPLSEDDWDGWVRLTSEIGERVQLVGDDLFVTNPERL... | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | A4F804 |
Q9Z7E9 | FOLB_CHLPN | 7,8-dihydroneopterin aldolase | Chlamydia | MIAIERYQLIISKFRMWLFLGCSVEERHFKQPVLISVTFSYNEVPSACLSDKLSDACCYLEVTSLIEEIANTKPYALIEHLANELFDSLVISFGDKASKIDLEVEKERPPVPNLLNPIKFTISKELCPSPVLSA | Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. | Q9Z7E9 |
A9BHV0 | ENGB_PETMO | Probable GTP-binding protein EngB | Petrotoga | MKVYKAQLIKTVYKIEDLPPPDKKEIAFAGRSNVGKSSFLNAILGIKIAKVSSTPGKTRSINYYLVNDKYYFVDLPGYGFASVSKQEKERWNVLMNEYFKTRFSLSAVSLLIDHRHMPQKLDYAMVEWLKDLGTPFLFILTKSDKLTKSEKAKLFEDIKRSFSTYGEYIYMPFSSKTKEGLKEVLKTIGEILGDND | Necessary for normal cell division and for the maintenance of normal septation. | A9BHV0 |
B5FTI4 | RSMF_SALDC | rRNA (cytosine-C(5)-)-methyltransferase RsmF | Salmonella | MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRINTLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEASSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGAILANEFSASRVKVLHANISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNLDIAATQRELLNSAFHALRPGGTLVYSTCTLNRQENEEVCLWLKETYADAVEFLPLGDLFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKMSSLPAMPAP... | Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | B5FTI4 |
B0S2F7 | KTHY_FINM2 | dTMP kinase | Finegoldia | MFITFEGPDGSGKSTIIQKVYDYLIENNYDVIKTREPGGSPIAEKIRNLILDTENIKMGYRTEALLYAASRAQHVEETILPALNENKIVLCDRFLISSLAYQGVGRGLGIENVRNINEFAINGVFPDFVLFFDVDPITTLKRKSSLDTADRLEKEGNNFHERVYNGYKEILNSEKNIEIIDATQSVEDVFSQCIEVLKRRNVL | Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. | B0S2F7 |
Q21179 | NAS18_CAEEL | Nematode astacin 18 | Caenorhabditis | MCASCLHNANAASFLMETFSRHRLNFICIGKMNIFYNVTSLDNKYSFHNPSAPVPHSSHALSSRQAHFTSFRAPVAPPSRPRRSQLPSSAKLLYCFDSSFSTEKRELMLFSMNFISSQTCVTFEENCSIPNRVQLVNGKGCSSYIGMNNIVQHLTFNDTCIDFGTAVHELMHALGVIHTHSRLDRDNFLNINLTNVSKEMMHNYAIFNQSTNVVPYEYGSTMHYYANISTMFPKKSEYSATLGIGRVTFYDMVILNTAYNCKCPNELLCGNGGYTNPSKCSECICPLGYGGVLCDRPSLIGKDTGLPLEVKDKIIEVKVV... | Metalloprotease. | Q21179 |
Q98KL7 | KUP2_RHILO | Probable potassium transport system protein kup 2 | Mesorhizobium | MDLASRDSEAETVEQSSHSGAEQHSTKVLMLGALGVVYGDIGTSPIYAFREALHASPGIDTRAQVLGVLSLIVWALTIIVTIKYVAFVLRADNKGEGGTLSLMSLARTAYPKGARLILAIGLCGAALFFGDSIITPAISVLSAVEGLRVVTPTLDPYVVPITLLILAILFSVQRFGTGKVAAVFGPVTALWFLAIGVAGLYHLLDDPSILLAINPYYAVTYLASTPTAAFVTVGAVFLAVTGAEALYVDLGHFGRKPIVLAWFSVVFPCLLLNYFGQGAFVLANGGRPTNPFFQMLPDWALMPMVGLATAATVIASQAVI... | Transport of potassium into the cell. | Q98KL7 |
C5CP50 | RL2_VARPS | 50S ribosomal protein L2 | Variovorax | MAVIKMKPTSPGQRGAVKISRDHLFKGAPHAPLLEPQFQKAGRNNNGHITIRHRGGGAKHHYRVVDFVRNKDGIPAKVERIEYDPNRTAHIALVCYADGERRYIIAPRGLEAGATLLSGSEAPIRAGNTLPIRNIPVGSTIHCIELQPGKGAQIARSAGTSATLLAREGVYAQVRMRSGEVRRIHIECRATIGEVANEEHSLRQLGKAGVKRHMGIRPTVRGVVMNPVDHPHGGGEGKTGEGRHPVDPWGNLTKGYRTRNNKRTQVFIVSRRKK | One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. | C5CP50 |
A6V0K2 | RF3_PSEA7 | Peptide chain release factor 3 | Pseudomonas | MTTQAAEVAKRRTFAIISHPDAGKTTITEKLLLMGKAIAVAGTVKSRKSDRHATSDWMEMEKQRGISITTSVMQFPYREHMINLLDTPGHEDFSEDTYRTLTAVDSALMVLDGGKGVEPRTIALMEVCRLRDTPIVSFINKLDRDIRDPIELLDEIEAVLKIKAAPITWPIGCYKDFKGVYHLADDKIIVYVPGHGHERIETKIIDKLDSDEARAHLGDLYDNFVEQLELVQGACHTFDKDAFLKGEMTPVFFGTALGNFGVDQVLDCIVDWAPQPLSRATHERNVEPTEEKFSGFVFKIQANMDPKHRDRIAFMRICSG... | Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. | A6V0K2 |
A0KN93 | RLMH_AERHH | rRNA (pseudouridine-N3-)-methyltransferase RlmH | Aeromonas | MKIQLIAVGTKMPAWVEHGFEEYRRRFPKDMPFELVEIGAGKRGKNADIPRILQKEGEAMLAAAGRSRIVTLDIPGKPWTTEQLAVQLEAWKLDGRDVALLVGGPEGLSPECKAAAEQSWSLSPLTLPHPLVRVLVAESLYRAWSITTNHPYHRE | Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. | A0KN93 |
Q7MYH5 | RPOA_PHOLL | Transcriptase subunit alpha | Photorhabdus | MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADIIHDGDVEIVKPQHVICHLTDETASISMRIKVQRGRGYVPASARIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLEN... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Q7MYH5 |
Q8YDB0 | DAPE_BRUME | N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase | Brucella | MTLPVNPVDNLAALIRCPSVTPAEGGALTALEKMLKLMGFSANRPVFSDDNTPDIENLYARKSGNGPHLMFAGHTDVVPPGDEKDWKHPPFAAAIEDGVMYGRGAVDMKGGIACFVAAVARHIEKHGNIKGSISFLITGDEEGPAVNGTVKLLEWAKQRGESWDASIVGEPTNPNALGDMIKIGRRGSLSGTITVHGVQGHAAYPHLAENPVRGIVTLVDSLLCPAFDEGTANFQASNLEVTTIDVGNKATNVIPNKATASFNIRFNDTWTAESLQAEIISRLERAARDNRLRQGRETPIKYELTWRERPSHVFLTHDEK... | Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | Q8YDB0 |
A6TD39 | ISPD_KLEP7 | MEP cytidylyltransferase | Klebsiella | MAATFPGVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHAVAALLADARVQRVVIAVSPGDRRFSQLPLAQHPQITVVDGGAERADSVLAGLQALPEAQWVLVHDAARPCLHQDDLSRLLSLCETSRVGGILAAPVRDTMKRAEPGKTAIAHTVDRNDLWHALTPQFFPRELLVDCLTRALNEGATITDEASALEYCGFHPQLVAGRADNIKVTRPEDLALAEFYLTRSRHQEKA | Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | A6TD39 |
Q3AHM2 | ATPB_SYNSC | F-ATPase subunit beta | unclassified Synechococcus | MVASAPASAGTKGVIRQVIGPVLDVEFPAGKLPKIYNALRIEGKNPAGDDVALTAEVQQLLGDHRVRAVAMSGTDGLVRGMEAVDTGAPISVPVGEGTLGRIFNVLGEPVDEQGPVNTTATAPIHRDAPNITELETKPKVFETGIKVIDLLAPYRQGGKVGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYEEFKESGVINADDLSKSKVALCYGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFVDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGALQERVASTVEGSITSIQAVY... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Q3AHM2 |
P0AFY7 | SBMA_ECO57 | Peptide antibiotic transporter SbmA | Escherichia | MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQIPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLVEVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVSHYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIAFLPVLVTLSAHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFN... | Uptake of antimicrobial peptides. | P0AFY7 |
Q2G8W3 | RS5_NOVAD | 30S ribosomal protein S5 | Novosphingobium | MADETNLEGVAAVEATGGEPQREGRGRGRGRGGNDRGGERGGRGRRDDRRGRGNNDEEGGEELIEKLVHINRVSKTVKGGKRFGFAALVVVGDGKGRAGFGKGKAREVPEAITKATAAAKRAMVRVPLKEGRTLHHDGKGRFGAGKVNVRSAPAGTGIIAGGPMRAVFESLGVSDVVTKSVGTSNPYNMIRATFDALTDQTSPKSVAQRRGKKVADLLGRGGASQVEAEAAAEAIAE | Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. | Q2G8W3 |
Q7M8F5 | RS11_WOLSU | 30S ribosomal protein S11 | Wolinella | MAKRKVTNKKRVVKKNIARGIIHIAATFNNTSVTITDEMGNVICWSTAGALGFKGSKKSTPYAAQQAVEDAVVKAKEHGIKELGIKVQGPGSGRETAVKSLGSIEGIKVLWFKDVTPLPHNGCRPPKRRRV | Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome. | Q7M8F5 |
A1K5T8 | SSRP_AZOSB | Small protein B | Azoarcus | MSIIDNRKAYHDYFIEEKYEAGLVLEGWEVKAIRAGRANIKEAYIIVRGEEIFILGMHITPLASASTHIRTDPTRTRKLLLHGAEIARLIGKVERAGFTLVPLDLHYAKGRVKAEIGLAKGKKQYDKREDEKKRDWEREKQRLMRVKA | Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb... | A1K5T8 |
Q8NJQ5 | CHI37_TRIHA | Chitinase 37 | Trichoderma | MTRLLDASFLLLPVIASTLFGTASAQSTCATKGKPAGKVLQGYWENWDGSANGVHPGFGWTPIENPVIAQNGYNVINAAFPVILSDGTALWEDGMDATVKVATPAEMCQAKAAGATILMSIGGATAGIDLSSSTVADKFISTIVPILKQYNFDGIDIDIETGLVGSGSIGTLSTSQANLIRIIDGVLAQMPANFGLTMAPETAYVTGGSVVYGSIWGSYLPIIKKYVDNGRLWWLNMQYYNGDMYGCSGDSYAAGTVQGFTAQTDCLNNGITIQGTTIKVPYNMQVPGLPAQSGAGGGYMTPALVGQAWDHYNGALKGLM... | Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Plays a morphogenetic role during apical growth, cell division and differentiation (cell wall morphogenesis). May be involved in the degradation and... | Q8NJQ5 |
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