Datasets:
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Dataset card Data Studio Files
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accession
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name
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Full Name
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147
⌀
taxon
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46
⌀
sequence
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16
2.75k
function
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5.51k
AlphaFoldDB
stringlengths
6
10
Q8S8X4
PSAA_ATRBE
PsaA
Atropa
MIIRSPEPEVKILVDRDPVKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVRGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEYILNRDLLAQLYPSFAEGATPFFTLNWSKYADFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGATAPGATASTSLTWGGGDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPERGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSVSDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIITVG
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
Q8S8X4
P55238
GLGS_HORVU
Alpha-D-glucose-1-phosphate adenyl transferase
Hordeum
MAMAAAASPSKILIPPHRASAVTAAASTSCDSLRLLCAPRGRPGPRGLVARPVPRRPFFFSPRAVSDSKSSQTCLDPDASTSVLGIILGGGAGTRLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVLTQFNSASLNRHLSRAYGSNIGGYKNEGFVEVLAAQQSPDNPDWFQGTADAVRQYLWLFEEHNVMEYLILAGDHLYRMDYEKFIQAHRETDADITVAALPMDEERATAFGLMKIDEEGRIIEFAEKPKGEQLKAMMVDTTILGLEDARAKEMPYIASMGIYVISKHVMLQLLREQFPGANDFGSEVIPGATSTGMRVQAYLYDGYWEDIGTIEAFYNANLGITKKPIPDFSFYDRSAPIYTQPRHLPPSKVLDADVTDSVIGEGCVIKNCKIHHSVVGLRSCISEGAIIEDTLLMGADYYETEADKKLLAEKGGIPIGIGKNSHIKRAIIDKNARIGDNVMIINVDNVQEAARETDGYFIKSGIVTVIKDALLPSGTVI
This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
P55238
Q9LYE5
CID5_ARATH
Protein INCREASED POLYPLOIDY LEVEL IN DARKNESS 1
Arabidopsis
MKPGAFALNPHAASYVPISKRVDYGGGDDGLVFAAKSPTVEVSMPKKSSEMAYKQIRDDDLDLEMDIDMDIEYLLVTFSGLSQESITDVYLANGGDLEATIEMLNQLEIYSTESEENLPETLDIGDISESGPSTSKSTEVAASTSSVIPNAPVSA
Promotes polyploidy in dark-grown seedlings. Regulates the endocycle leading to hypocotyl elongation.
Q9LYE5
Q9RRL7
ACSA_DEIRA
null
Deinococcus
MTHPNDHIDAMLHETRVIHPSAEFQAGTRVSRAEYERRYRQSLDQPDDFWSEVAHDLHWMKDWDRVLDWQEPHAQWFVGGQTNIAYNALDRNVQRGLGDKRAIIWEGEDGEVRTYTYAELLREVCKAANALEELGVVAGDRVTLYMPLIPEAAIAMLACARIGAVHSIVFGGFSVSALADRINNAQSKLLITADAGYRRGKPVTLKINADEAAKLAPCLEHVLVVKRAGIPLEWWTEGRDLWWHDVVDRQSDQHEATALDSEHPLFILYTSGSTGAPKGVQHTTGGYMVGTYLTTQTVFDLRDDDIYWCTADIGWITGHSYSVYGPLLNGATVVMYEGAPNQPDWGRFWDIVQKHRVTILYTAPTAIRSFMQHGDEIPGRYDLASLRLLGSVGEPINPEAWMWYYRVIGGERCPVVDTWWQTETGSIMLTTLPGAFPSKPGSAGLPMFGVEPALMTRDGEEIGDDDGGLLVIKRPWPSMLRTVYGDDERYRKSYWGEIPHVYFAGDGARRDHDGYYTIVGRVDDVLNVSGHRLGTMEIESALVAHPDVSEAAVVGRPDPVKGESVVAYVLLQDGHTADPAALRAHVSSEIGALARPDAIYIADALPKTRSGKIMRRFLRQLAAGQPVQGDTSTLEDPTVLERLQASPAL
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
Q9RRL7
A0A1B0GUS4
UB2L5_HUMAN
Ubiquitin-protein ligase L5
Homo
MAASRRLMKELEEIRKCGMENFRNIQVDEANLLTWQGLIVPDNPPYNKGAFRIEINFPAEYPFKPPRITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSNDRKKFCKNAEEFTKKYGEKRPVD
Catalyzes the covalent attachment of ubiquitin to other proteins.
A0A1B0GUS4
Q47LJ7
RS19_THEFY
30S ribosomal protein S19
Thermobifida
MPRSLKKGPFVDHHLMKKVLEQNEKGTKNVIKTWSRRSMVVPEMIGHTIAVHDGRKHVPVFITEAMIGHKLGEFAPTRTFRSHVKEDRRSRR
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
Q47LJ7
Q59468
HMDH_HALVD
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Haloferax
MTDAASLADRVREGDLRLHELEAHADADTAAEARRLLVESQSGASLDAVGNYGFPAEAAESAIENMVGSIQVPMGVAGPVSVDGGSVAGEKYLPLATTEGALLASVNRGCSVINSAGGATARVLKSGMTRAPVFRVADVAEAEALVSWTRDNFAALKEAAEETTNHGELLDVTPYVVGNSVYLRFRYDTKDAMGMNMATIATEAVCGVVEAETAASLVALSGNLCSDKKPAAINAVEGRGRSVTADVRIPREVVEERLHTTPEAVAELNTRKNLVGSAKAASLGFNAHVANVVAAMFLATGQDEAQVVEGANAITTAEVQDGDLYVSVSIASLEVGTVGGGTKLPTQSEGLDILGVSGGGDPAGSNADALAECIAVGSLAGELSLLSALASRHLSSAHAELGR
Catalyzes the NADPH-dependent reductive deacylation of (S)-3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to (R)-mevalonate. Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. Is also able to catalyze the reduction of mevaldehyde to mevalonate and the oxidative acylation of mevaldehyde to HMG-CoA.
Q59468
Q3MD46
MURI_TRIV2
Glutamate racemase
Trichormus
MYSSSSIEGNLYGFSEQEPQRAPIGVFDSGVGGLTVLRQIYRQLPNESVIYFGDTARLPYGIRSQAEILTFVRDILDWMQQQHVKMVVMACNTSSALALDIVREEYDFPILGVILPGAKAAVQQGKRIGVISTPATAKSNAYRQAIWEIDPNVEVWQVGCPEFVPLIEQNRIQDPYTTEVARAYLEPLIQQDIDTLVYGCTHYPLLAPVLRSLLPPQVKIIDPAVHVVTACTQELDILGLSNTHPPLPTRFAVSGCPQQFSQSGVNWLGYTPLVEAVDFTGIPVSQLQQDLA
Provides the (R)-glutamate required for cell wall biosynthesis.
Q3MD46
A9MWU8
RNB_SALPB
Exoribonuclease II
Salmonella
MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIVAVIHTEKERESAEPEELIEPFLTRFVGKVQGKNDRLSIVPDHPLLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFVPWWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELADGRLQLTVAIADPTAWIAEGSKLDNTAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPALACRMIIAADGTIDDDIAFFAATIESKAKLAYDNVSDWLENNGTWQPDNEGIAQQIRLLHRICLSRSEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFCKLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGEAIARPQEDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTNTRFAAEIIDVSRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPAA
Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
A9MWU8
B7ZS96
TTHY_XENLA
Prealbumin
Xenopus
MASFKSFLLLALLAIVSEAAPPGHASHGEADSKCPLMVKVLDAVRGIPAANLLVNVFRQTESGKWEQITSGKTTELGEIHNLTTDEQFTEGVYKIEFATKAFWGKLGLSPFHEYVDVVFTANDAGHRHYTIAVLLTPYSFSSTAIVSEPHDDL
Thyroid hormone-binding protein, with a much higher binding affinity for triiodothyronine (T3) than for thyroxine (T4). Probably transports triiodothyronine from the bloodstream to the brain.
B7ZS96
Q75K18
SRP54_DICDI
Signal recognition particle 54 kDa protein
Dictyostelium
MVLADLGNQLSSALRSLNETTIVNEDTINQLLKEVGNALSKSDVSMSLIIQMRKNIKDKIKLDQMAAGLNKRKIIKQVVFDELIRLLDPGVPLWKPTKGKSNIVMFVGLQGAGKTTSVTKLAYFYKKKGFSTAIVCADTFRAGAFDQVRHNAAKAKIHYYGSETEKDPVVVARTGVDIFKKDGTEIIIVDTSGRHKQDSELFEEMKQIETAVKPDNCIFVMDSSIGQAAYEQATAFRSSVKVGSIIITKMDGNSMGGGAISAVAATNTPIIFIGTGEHLTDLELFDPSTFVSKLLGYGDMKGMLEKIKEVIPEDSTSLKEIAQGKFTLRSMQQQFQQIMQLGPIDKLVQMIPGMNQLPQLQGNEGGLKLKAYINILDSLSEKELDGKKPITQKRIITIAQGSGRHPNEVVELLEQHKTFEKLIGKGGPGGGLGSLMAGKGGPKNMEQAMKQMNANGGMQGLMNSLKGMGGMGDLAKMFGGGGGGGGGMPSMGDLAKMMGGMGGGGRGGGGMPNMGDLAKMMGGMGGGAGKGGQNGFPNLDLD
Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
Q75K18
Q1AXL7
GLMU_RUBXD
Glucosamine-1-phosphate N-acetyltransferase
Rubrobacter
MAQAGSASPLFAVVLAAGKGTRMKSNRAKVLHTLCGVPMVNYVIGAIRPLVPERLLVVVGHQAEQVRAVLPEDAEPVLQPEQRGTGDAVRVALEAIPEEEGVLLVVNGDGPLISDRTLGELLERHRSAGVGATVLVAELPDPSGLGRVREDAGVVRITEERDATEAERRNRLCNLGLYAFELPELRRAIREISSGAGRGELYLTDVLEIIGRRSRAVTYRLKDLEEANLVNDRSQLARAEEILRRRILDAHMKEGVTVRDPVSTHIEASVEIGRDTVILPGTFLRGRTRIGSDCVIGPSTDLVDTVVEDGATVEHSVGRGARVGRGAAVGPYAYLRPGTVLEEGSKVGAFCEVKNTRVGARSKVPHLSYVGDAEIGEDANLGAGTITANYDGAKKHRTVIEDGAFTGINTNLIAPVTIGQGAYLGAGSVVNKDIPPGKLAVGAPARVIRDAPGARSSSGDRRRARTEG
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
Q1AXL7
B0KBA3
CLPX_THEP3
ATP-dependent Clp protease ATP-binding subunit ClpX
Thermoanaerobacter
MAKYDNQKQLKCSFCGKTQDQVKRLVAGPGVYICDECIELCQEIINEEFEEDMDMGIGELPKPKEIKEFLDQYVIGQEKAKKALAVAVYNHYKRINSRIKPDDVELQKSNILLLGPTGSGKTLLAQTLAKLLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDIEKAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPHQEFIQIDTTNILFICGGAFEGIEKIIESRIGKKSLGFGAEVQSRKEKDLSEILSHIMPQDLLKFGMIPEFIGRVPIVVTLDPLSKDDLVRILTEPKNALTKQYEKLFELDGVKLEFDKKALGLIADMALERKTGARGLRAILEEIMLDVMYEIPSSDNIEKCIITEETVLKKAPPTLVYSDAQKAKKKIKKTESVS
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
B0KBA3
Q8JGS0
RU1C_DANRE
U1 small nuclear ribonucleoprotein C
Danio
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFPGAPPPGGSLLPHPSIGGPPRPGMLPAPPMGGPPMMPMMGPPPHAMMPGGPGPGMRPPMGGPMQMMPGPHMMRPPARPMMPAVRPGMVRPDR
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Q8JGS0
B2IK83
KAD_BEII9
Adenylate monophosphate kinase
Beijerinckia
MRLILLGPPGAGKGTQSERLREQCKIPQLSTGDMLRAAVKAGTPIGLKAKAVMDAGGLVSDDIVVGIVADRIEEPDARNGFILDGFPRTVKQAEALTTMLHEKKMDLDAVIELVVDENALLARIEKRAKETLAAGGTVRADDNPAAFKTRIDTYREQTAPVSAYYASQGVLKTVDGMADIDTVTAAIDKILKA
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
B2IK83
Q29PU2
SAU76_ARATH
Protein SMALL AUXIN UP RNA 76
Arabidopsis
MAKGGNKLMKLKSVLKKLNSFNTKPNQPPAQTNHSRSSAVSAFPSEDLQTVYVGRTRRTYHVSSDVVSHPLFQQLAAVDGGCGSEDGSISVSCEVVLFEHLLWMLENADADESRPESVYELVEFYAC
May be involved in the regulation of ethylene receptor signaling. Promotes cell expansion and plant growth (Probable). Involved in the regulation of cell elongation .
Q29PU2
O66435
RS19_AQUAE
30S ribosomal protein S19
Aquifex
MGFKGAWNKRNRLIENPEEYYRLYKKLQRAYKLVREAIKRYGSFELLKGKNTLPELEALLEERKLVLENLKKQLKEAHKGKPKIEAEGDEKLKELIREVNKAQAEVRALEIIVNRVRKYEELYAQYKQMTEKKAYVDPKLWVRIRKMNETGERKVVRTYSRATTIIPEFVGHTIAVHNGKTFVPVYITQDMVGHKLGEFAPTRTFKGHPEKTAKVVKKK
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
O66435
B9KL95
RS19_CERSK
30S ribosomal protein S19
Cereibacter
MARSTWKGPFVDGYLLKKAEKSRESGKNEVIKIWSRRSTILPQFVGLTFGVYNGKKHVPVNVTEEMIGQKFGEYSPTRTYYGHAADKKAKRK
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
B9KL95
Q06922
TGFA_PIG
TGF type 1
Sus
MVPSAGQFALFALGILLAVCQALENSTSALSADPPIAAAVVSHFNDCPDSHSQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVLIHCCQVRKHCEWCRALICRHEKPSALLKGRTACCHSETVV
TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
Q06922
P0CAQ7
CA16B_CONLE
Alpha-conotoxin-like Lp1.6b
Lithoconus
VVLGPASDGRNAAANNKASDLIRQICCGYGDCGFVPNVCV
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
P0CAQ7
A9EXF3
THIG_SORC5
Thiazole synthase
Sorangium
MTSDALTIGRYTFTSRLFVGTGKYKDLDETRRALEASGAEVVTVALRRVNLKERGEGSMMSLLQQGRVTILPNTAGCYTVEDAVRTCRLARELGLSDLVKLEVIGDERTLFPDNEATLEAARILVKEGFTVLPYCMDDPIVCRKLEDIGCAAVMPLAAPIGSGLGIRNPYNLMIIRETAKVPVIVDAGVGTASDAAVAMELGCDGVLMNTAIAGARDPILMAQAMKDAVRAGRMAYLAGRMPKKLYATASSPEQGKIAAL
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
A9EXF3
Q1AYH3
HUTU_RUBXD
Imidazolonepropionate hydrolase
Rubrobacter
MTDGKTTTVRAPRGTELSCKGWHQEGALRMLMNNLDPEVAERPEELVVYGGTGKAARSWECFWAIVEALRGLDGDETLLVQSGKPVAVFRTHPWAPRVLIANSLLVPEWADWETFRELERAGLTMFGQMTAGSWIYIGTQGILQGTYETFAALAEQRFGGTLRGRVCLTAGLGGMGGAQPLAITMNEGVALCVEVDPRRIDRRLEHRYLDERIDDLDAAVERAEEARREGEPLSIGIPGNAAEVFPALLERGYVPDAVTDQTSAHDPLGGYIPAGYTLEEAAELREADPGRYVREARASMARHCAAMVGFMERGAEVFDYGNNLRGEARLGGFERAFSYPGFVPAYIRPLFCEGKGPFRWAALSGDPDDIAATDEAVLELFPENGRLVRWIRQARERVRFQGLPARICWLGAGERHRAGLRFNELVAGGTISAPIVIGRDHLDSGSVASPYRETEGMRDGSDAIADWPVLNALLNTASGASWVAVHHGGGVGIGKSIHAGAQVVVDGTEEGAARIERVLTNDPSLGVVRHADAGYERAREAARALGIRMPMLGR
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
Q1AYH3
B1WR90
PDXH_CROS5
Pyridoxal 5'-phosphate synthase
Crocosphaera subtropica
MDLTALREEYTRHGLTRDDLEDNPFKQFEKWFQQATEAELSEPNAMSLATASAKGEPSIRTVLLKYFDEKGFVFFTNYESRKAQQIEENPHVALLFLWLPLERQVKIQGTATKVSTAESLNYFTSRPRGSQLGAWCSAQSSVISSRKLLEMKFEELKYKFQHGEIPLPSFWGGYRVKPTRFEFWQGRPNRLHDRFSYTLTETDDTTWGIHRLAP
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
B1WR90
Q96DR5
BPIA2_HUMAN
Short palate, lung and nasal epithelium carcinoma-associated protein 2
Homo
MLQLWKLVLLCGVLTGTSESLLDNLGNDLSNVVDKLEPVLHEGLETVDNTLKGILEKLKVDLGVLQKSSAWQLAKQKAQEAEKLLNNVISKLLPTNTDIFGLKISNSLILDVKAEPIDDGKGLNLSFPVTANVTVAGPIIGQIINLKASLDLLTAVTIETDPQTHQPVAVLGECASDPTSISLSLLDKHSQIINKFVNSVINTLKSTVSSLLQKEICPLIRIFIHSLDVNVIQQVVDNPQHKTQLQTLI
Has strong antibacterial activity against P. aeruginosa.
Q96DR5
O17611
NH100_CAEEL
Nuclear hormone receptor family member nhr-100
Caenorhabditis
MNIPFNSVSKIQWRNPSPVSDTSCLVCGDPHGKRHYGAMSCNGCKGFFRRSIWEKRTYKCSFNNECIIEFKYRNRCRACRLKRCLHVGMDANAVRSERTRKIKTEIDGDVKLEIKEEPADSEDADDECPLDIKPDIAMAWQTKEIIAHMLYEEDRVLNWEEPYNKLRYYTMDSEVLQAIKDPSQVCARTKINWNSHSRPLITIEALRFNWCRTFTLTIDWFETLPEYRALIDDDKELLVKFSLMPVGWLWYAYKSYEYRCDGIVFVDGSWFPRDKTIQQQVCPTCVLYYGRITESFMADVVNSMKELEMDETEMVLLKAICHLQPDYRLTRRGNDVISTGREKYKRALCEYIRMKSNGFMDASFRLCKLMQILPVVDILGKYEDESALLVSLGETEFNGSGGGLPYDIHASDSHFARKNRRKSDNQYHQQHVPLHIQ
Orphan nuclear receptor.
O17611
Q55G32
EXPL6_DICDI
Expansin-like protein 6
Dictyostelium
MIKIIYLIVLLVLLFKNNHIIIKADDCPFPQIPIKTLSGTWYDDPDHASCGFEKLTGPLGPGNRLVVALGSKLFDKGANCGQCYDVTSPFNNKTITVMATDSCHDAGYCQADNHFDFYKEAFDLLGSPSGVISGNSGLSYIKVPCPTYGNVKIMMKDGSNEFWTSFLIFNSRILIKQVSIKLSNSQQFIDLNRQPQGNYWPSTNMVSGEFEVRIESIGGEFIYVKIPSIESRKIYDTGNQFSADGCVGNKYDPYAPFQITSNSNNILPPSLYIIFLISILFLIINNIFSNKY
May serve to lubricate the movement of the cellulose microfibrils during cell growth and wall extension and/or may serve to maintain the fluid state of the slug cell wall.
Q55G32
Q8DST6
UPP_STRMU
UPRTase
Streptococcus
MGKFQIISHPLIQHKLSILRRKDTSTKHFRELVNEIAMLMGYEVSRELPLEEVEIETPITKTVQKQLTGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRDEETLEPVEYLVKLPEDIDQRQIFVVDPMLATGGSAVLAIDSLKKRGAANIKFVCLVSAPEGLKKLQEAHPDIDIYTAALDEKLNEKGYIVPGLGDAGDRLFGTK
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
Q8DST6
A0Q3H1
KHSE_CLONN
Homoserine kinase
Clostridium
MIKVKVPGTTANMGPGFDSFGMALDIYNEITVEEIESGFEMLQEGELSEIPLAENLIYTTFLNTLNKHNYKYKGFRINLSKCDVPMSRGLGSSATCIVGGIFAANSIMGNVMSFDEIIKEAVSIEGHPDNVVPAIVGGMTVSIMDKDNVIYSNVTVPDRLRAFVMIPNYKLGTEEARGVLPDSYTREECVFNISRAAMLVNVMNNGEIEKLRLCMQDKIHQKYRGALIRNIDDIFKKAYEFGSLAEFISGSGSTLIAFIDKDNNEFYDRMKNFLDTLEDEWTVHLLKPNFTGAEIIKNR
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
A0Q3H1
A8FSF3
HCP_SHESH
Prismane protein
Shewanella
MFCIQCEQTIRTPAGNGCSYSQGMCGKLAETSDLQDLLIYVLQGVSAYAVKAREFDIIDHEIDTFVPKAFFATLTNVNFDDARLVEYVEQANAYRGRLQDAYETACTAKGVTPEQMSAPAQLILATSKPEMITQAAQAAPNRGDVHEDILGLRLLCLYGLKGAAAYMEHARVLSQTNDEVAGQFHEIMAFLGEDSVDVDKLFATSMEIGQLNYKVMAMLDEGETESFGHPEPTQVNTVAVKGKAILVSGHDMVDLELILKQTEGKGINVFTHGEMLPALAYPEFKKYPHLVGNYGSAWQNQQKEFANFPGAVVMTSNCIIDPNVGSYADRIFTRSIVGWPGVTHLVGDDFTPVIEKALALDGFIYDEIPHLITIGFARNALMAAAPAVIDNVKNGSIKHFFLVGGCDGDKAERSYFTDIATQAPDDSVILTLGCGKYKFNKLEFGDINGIPRLLDIGQCNDSYSAIQLAIALSEAFECEINELPLSIVLSWFEQKAIVVLLTLLSLGVKNIRTGPTPPAFLTPNLLKILEDKFGLRNTTTVEEDLKTILNVA
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
A8FSF3
Q02780
NFIA_MOUSE
TGGCA-binding protein
Mus
MKLADSVMAGKASDGSIKWQLCYDISARTWWMDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPSQPSEADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGLPSPSTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPMPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Q02780
A8AMR3
CUTA_CITK8
Divalent-cation tolerance protein CutA
Citrobacter
MLDDNSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
Involved in resistance toward heavy metals.
A8AMR3
A7H2Z6
THIG_CAMJD
Thiazole synthase
Campylobacter
MQENLKNDKLKIGKYEFDSRFILGSGKYSLELIKSSIEEAKAQIITLALRRANTGEIANILDYIPKNITLLPNTSGARNADEALRIARLSRELGCGELIKIEVISDSRYLLPDNYETIKACELLAKEGFTPLPYMHADLYAARAMRDVGAAAIMPLAAPIGSNKGLCAKEFIQILLNEIDLPIIVDAGIGTPAQACEAMQMGVSAVMVNTAIAEAKDIALMARAFSLAVNAGRAAFLAGLASVSEAKASSPLTGFLRD
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
A7H2Z6
Q7MGZ2
GPMI_VIBVY
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Vibrio
MSAKKPLALVILDGYGYREDTASNAIANAKTPVMDALIANQPNTLISASGMDVGLPDGQMGNSEVGHTNIGAGRVVYQDLTRITKSILDGEFQQTAALVEAIDTAVKAEKAVHIMGLMSPGGVHSHEDHILAAVEMAAERGAEKIYLHCFLDGRDTPPRSAEGSLQRFQDLFAKLGKGRVASLVGRYYAMDRDNNWDRVQVAYDLLTQAKADFTYDSAVAGLAAAYERGENDEFVKATEIKAEGQESAAMQDGDAVIFMNYRADRARQITRTFVADFAGFERAAFPAVNFVMLTQYAADIPLAIAFPPASLENTYGEWLSKQGQTQLRISETEKYAHVTFFFNGGVETEFAGEERQLVASPKVATYDLQPEMSSTELTEKMVAAIKSGKYDTIICNYPNADMVGHTGVYEAAEKAIEALDASVGQVVEAIKEVGGQLLITADHGNAEMMVDPETGGIHTAHTSLPVPLIYVGDKAVEFKEGGKLSDLAPTMLSLAGLEIPAEMTGQVLVK
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Q7MGZ2
A8AJ37
GAL1_CITK8
Galactose kinase
Citrobacter
MSLKEKTQSLFAEIFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCATRDDRKVRVIAADYDNQVDEFSLDAPIVTHDSQQWSNYVRGVVKHLQKRNNAFGGADLVISGNVPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLGTKAVSMPEGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVSLAAFNAVASELDPIVAKRVRHVLTENARTVEAASALEKGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKATIGDKGGVRMTGGGFGGCVVALLPEALVPAVQQAVATQYEAKTGIKETFYVCKPSQGAGQC
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
A8AJ37
P42444
RECA_ENTFA
Recombinase A
Enterococcus
MADDRKVALDAALKKIEKNFGKGSIMKLGEKADQKISTIPSGSLALDVALGVGGYPRGRIIEVYGPESSGKTTVSLHAIAEVQRNGGTAAFIDAEHALDPQYAEKLGVNIDELLLSQPDTGEQGLEIADALVSSGAIDIVVIDSVAALVPRAEIDGEMGASHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPETTPGGRALKFYATVRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKVAEVDIMYGQGISQEGELLDMAVEKDLISKSGAWYGYKEERIGQGRENAKQYMADHPEMMAEVSKLVRDAYGIGDGSTITEEAEGQEELPLDE
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
P42444
Q5ASK9
TRM44_EMENI
tRNA (uracil-O(2)-)-methyltransferase
Aspergillus subgen. Nidulantes
MARALALSRSVQVCKSRLFTVASKSAITKRCLSNPIQYRSVSLFATTYAPSKDLNSRLHSEHIGDTALYLLLNPGLTSSVLFRADILAQSGKCPTLAALEAQKQQETEEASTATAMTMAQNVIEEEKEVKEPVVEIPAREVPGFELHKTLIRRLIPRNQQLDMPVDQTCHLYSHAGAVEQIEKEKELGIPHSRAPKERFMVIYTPHVSSKEELPYYHPLVRSMAFVYEFGYTGEFEGPENSIPRIAENPKGTMSIHFLPYENDVDSISARLERSLTKLIEVQIRTTKGRLDPCRPSTSSPYALIKDNVIPRNRVQDTYSRLKNKYAANLNERWIESTEPSKHVFEDLSIAAFLIELWRDLYGAVPGDEREQQKQQSSTSKVGSGQFPGFVDIACGNGVLVYILISEGYSGWGFDARRRKTWSIFPTDVQERLKEEIYIPKPFMDVLAAQNQGPIQNKNQDASMQSPLSEPQSGQSNGPNSGTSTSTSLSNLPKDTFIISNHADELTLWTPILSTLLNPANPPPFLAIPCCSHSLSGARHRFRPQSARPSATQNPQKQQGENGTHSQDEEGSSEDMKERKGEEKEKNPETGDLEQMRKDKLAAQNPH
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
Q5ASK9
B9MDP9
LEPA_ACIET
Ribosomal back-translocase LepA
Diaphorobacter
MNHIRNFSIIAHIDHGKSTLADRIIQRCGGLADREMEAQVLDSMDIEKERGITIKAQTAALQYKARDGKVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTALDLGVEVLPVLNKMDLPQADPDTAKAEIEDVIGIDASEAIAISAKTGMGIDDVLEQIVAKVPAPRGKPDAPLRAMIIDSWFDSYVGVVMLVRVVDGRLQKGERFKMMASGAAYEANNLGVFTPAQQSRDALEAGEVGYIIAGIKELKAAKVGDTITLEKKLPNNLGPATEALPGFKEIQPQVFAGLYPTEANQYDALRDALEKLQLNDASLHFEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDQDLITTAPSVVYEVVKGDGEVIMVENPSKMPDQGKIQEIREPIVTVHLYMPQDYVGPVMTLANQKRGVQMNMQYHGRQVMLTYELPLGEIVLDFFDKLKSVSRGYASMDYEFKEYRPSDVVKVDILLNGEKVDALSIIVHRSQSQYRGRAVAAKMREIISRQMFDVAIQAAIGANIIARETIKALRKNVLAKCYGGDITRKRKLLEKQKAGKKRMKQIGSVEVPQEAFLAILQVED
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.
B9MDP9
Q493T7
IF2_BLOPB
Translation initiation factor IF-2
Candidatus Blochmannia
MTDTTIQSFAAEMKMSVDQLIQWFSYIGILKTEIGIVTQREKEILFKYMNDNKSDISKKLILQRKTRSILSVSSVGGKNKKVQIEIRKKLTYVQSTLQETEFIDVKNKMVLDANREASSLIVRNNRLVNKKISNTLGPSSLTKISKKNHRYSELIEHKEKVIGKISRKFEDKSLQDSDETQLLKKKTKNCWDIELNNTNAISSNLGDSSSNSKLYCMPELLEKNNNQKLENERRNRSRVRTRYRNGGKLTKQHKRGNHHRLYEATSDEFGMEEELYIPNRVNKSKRKQSALVQVFNKPVQTITRDIIIGQTISVAELANKMSIKSSRVIKTMMQLGIIATINQIIDQDTAQLVAEEMGHNVILRRENELEELIMNDRDIDITSSDTTLANRAPIVTIMGHVDHGKTSLLDRIRSTKIASSEVGGITQSIGAYHVSTDNGMITFLDTPGHAAFTAMRARGVQITDIVVLVVAADDGVMPQTIEAIEHIKAANVPVVVAINKIDKSEANPERIKNDLNNHGLIPEEWGGDTQFIHVSATSGNGIDNLLDAILLQSDMLELKVVHHGMARAIVIESFLDKGRGPVVAVLVREGTLKCGDIILCGTEYGRVRAMRNEFGHEITSAGPSIPVELLGLSGSPASGESVIVVRNEKKAREVALYRQGKSREIKLARQKEPNIENIFSSIKNTSVVSELNLIVKSDTKGSSEAIRESLENLSTGGDVTIKILSSSIGGITETDVALAAASNAVIVGFNVRADPTARRIIEADQLDVRYYSVIYDLIDEVKQAVHGMLAPRYKHEIIGLAKVRNVFRSPKYGNVAGCMVVEGMIKRYKKIRVIRDNIVVHEGELESLRRFKDDVNEVRSGIECGIGIKNYKNIHSGDMIEVFDMVKISHV
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Q493T7
P84570
PLS2_PITOR
Phylloseptin-5
Pithecopus
FLSLIPHAINAVSAIAKHS
Has antiprotozoal activity against T.cruzi.
P84570
B7NNT8
ARNF_ECO7I
Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF
Escherichia
MGLMWGLFSVIIASAAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLQGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
B7NNT8
Q1IWP0
VATE_DEIGD
V-ATPase subunit E
Deinococcus
MALDKLLEHEAQAEIERIRAEARDRAQQILASARERADALLESRRRLLETQRQAALVRARSAADLELSAARLTASEQGMAEVYRLVEGHLREITGLPEYREILARLIAEARQAIPEAEAVEVNPADLALARELVTDLSVRENPAIQGGVRVVARGGKSGITNTLAGRLDRLRGELAPQVSRLLAE
Produces ATP from ADP in the presence of a proton gradient across the membrane.
Q1IWP0
Q1LTT8
RL31_BAUCH
50S ribosomal protein L31
Candidatus Baumannia
MQKNIHPKYFEIRAICSCGNIIPTYSTLDQHLNLDVCSACHPFYTGKQRRVNTRGRVERFNKRFSLSIMNSKKKE
Binds the 23S rRNA.
Q1LTT8
Q96W72
XYNB_TALPU
1,4-beta-D-xylan xylanohydrolase B
Talaromyces sect. Talaromyces
MKVTAAFAGLLATTLAAPATELVTRSINYVQNYNGNLGAFSYNEGAGTFSMYWQQGVSNDFVVGLGRSTGSSNPITYSASYSASGGSYLAVYGWVNSPQAEYHVVEAYGNYNPCSSGSATNLGTVSSDGGTYQVCTDTRVNQPSITGTSTFTQFFSVRQGSRTSGTVTIANHFNFWAKHGFGNSNFNYQVVAVEAWSGTGTASVTVSA
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
Q96W72
A8MEA3
RECF_ALKOO
DNA replication and repair protein RecF
Alkaliphilus
MIVEELKLINYRNYEQMNLKFHPRLNVFIGDNAQGKTNLIESIYLCSAGKSFRTNHDQELINMNKKQAYIHVKVKKVHSDVHIEVRLNSERKKDLKVNQIPLVKMGELLGNLNVVLFSPEDLKLVKEGPSERRRFMDREISQISTKFYYTLSQYNKILQHRNKLLKYNKGKEIDIEVWDEQLAAAGAWLIVYRRNFIKKISILAKLMHRKITESIENLEVIYEPNVKVKENDEVDVIKEKILQNLKENFNVDKQRGLTTCGPHRDDMILKINGLDVKTYGSQGQQRTAVLSLKLAELELVKGEVGEYPILLLDDVMSELDSKRQHYLIHNLKSVQTFITTTMMETLKDLKPEDRAVFYVNKGQID
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
A8MEA3
C5Y210
NNRD_SORBI
ATP-dependent NAD(P)HX dehydratase
Sorghum
MSRPTGACPHAWRHQQQPLRGRMWAASPAFRRQLVLLRSLLPSPPAPSSVAGFPPSCPSCSSFLRVRTNHAMAASAGTVYEADAEAVVRRITPPLDRARHKGQAGKIAVIGGCREYTGAPYFAAISALKVGADLSHVFCTKDAATVIKSYSPELIVHPILEESYSVRDDERASVSSKILTEVGKWMERFDCIVVGPGLGRDSFLLDCVSNIMRHARQANIPTVVDGDGLFLVTNNLSLVEGNPLAILTPNVYEYKRLVQKVLNCDVDEETASEQLITLCQKIGDVTIMQKGKADVISDGKTVTQVSTFGSPRRCGGQGDILSGSVAVFASWARHFVLTNEQPTEKRKAASHAFEKNKRSTVTSDIIEFLGKSLEDICPAEH
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
C5Y210
A9B426
RL6_HERA2
50S ribosomal protein L6
Herpetosiphon
MSRIGRKPIEVPAGVTVNVDSNNLVTVKGPKGTLSESIRPEVTVNINGATVEITRVNDSRQARAFHGLSRTLVANMVDGVTKGFEKTLEMNGTGYRATLDGKTLVLSLGFSHPVRVEPYEGNSFEVAERRVVIKGPNKQKVGDQAANIRKLRPPEPYLGKGIKYSDEVIRRKAGKAGKK
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
A9B426
A0A286YFG1
SCGR8_HUMAN
Keratin-associated protein 28-8
Homo
MGCCGCGGCGGGCGGCSGGCGGGCGGGCGGGGCGGGCGSCTTCRCYRVGCCSSCCPCCRGCCGGCCSTPVICCCRRTCSSCGCGYGKGCCQQKGCCQQKCCCQKQCCC
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
A0A286YFG1
Q6YXN2
CYB6_PHYPA
Cytochrome b6
Physcomitrium
MGRVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEVNFGWLIRSVHRWSASMMVLMMILHIFRVYLTGGFKKPRELTWVTGVILAVLTVSFGVTGYSLPWDQIGYWAVKIVTGVPEAIPVIGSPLVEILRGSVSVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
Q6YXN2
P01353
GAST_CANLF
Gastrin
Canis
MQRLCVYVLILALALATFSEASWKPRSRLQDAPSGPGANRGLEPHGLDQLGPASHHRRQLGLQGPPQLVADLSKKQGPWMEEEEAAYGWMDFGRRSAEEGDQRP
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
P01353
C4LD55
NQRE_TOLAT
NQR-1 subunit E
Tolumonas
MEHYLSLFVKSIFIENLALSFFLGMCTFLAVSKKVKTAMGLGIAVVVVQAIAVPANNLVFTYVLKENALVQGMDLTFLGFITYIGVIAALVQILEMFLDRYVPSLYSALGIFLPLITVNCAIFGGVSFMVQREYNFPESVVYGVGSGISWALAIVLMAAIREKMKYSDVPPGLRGLGITFITAGLMALGFMSFSGISL
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
C4LD55
A4XES9
CARDI_NOVAD
NACOX1
Novosphingobium
MVTKGVVVVSSFRRSRQDANRPHAFLTGIHAPVKEERTIEDLAVTGTIPAELSGRYVRIGPNPFRADPRGHHWFVGDGMVHGVCMKGGKALWYRNRYVRSRNLQDAGGPAAAPGPRRSTFDTVNTNVIQHAGRTFALVEAGSFPVELTHDLESFAYSDLGGTLKGPFSAHPHLDPLTGELHAVTYDGQTLDTVWHVVVDREGRVRREEPVPVAHGPSIHDCAITAKYVLILDLPVTFSMAALVGGARFPYRWNPAHRARVGLLPREGTAADVIWCDVDAAYVFHVANAFDNPDGTVTVDLAAYETMFAHGPDGPNGKSLGMERWTVDPAARKVARKTLDAAPQEFHRPDERFFGQPYRFAWSMGLPAENAEDFLGHAPIYGYDLATGQRSAHDFGPGKIPGEFVFIPRRADAEEGDGWLMGYVIDLASETTDLAILDARNLAAPPLALIHIPCRIPPGFHGNWLPDAAD
Catalyzes the conversion of 8'-apo-beta-carotenal to 13-apo-beta-carotenone and C12-dialdehyde. Has also weak activity with 4'-apo-beta-carotenal and gamma-carotene.
A4XES9
C3KE92
YACG_PSEFS
DNA gyrase inhibitor YacG
Pseudomonas
MSQPLTVDCPTCGAPVEWTAANLNRPFCSDRCKLIDLGAWAAEEHKIPVAPDAEDELFSEDLPPRH
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
C3KE92
P0A316
PHEA2_PARMW
C-phycoerythrin class II alpha chain
Parasynechococcus marenigrum
MKSVITTVVGAADSASRFPSASDMESVQGSIQRAAARLEAAEKLAGNYDQVAQEAVDAVYNQYPNGATGRQPRKCATEGKEKCKRDFVHYLRLINYCLVTGGTGPLDELAINGQKEVYKALSIDAGTYVAGFSHLRSRGCAPRDMSAQALTAYNQLLDYVINSLG
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
P0A316
Q9FMP0
MD19A_ARATH
Mediator of RNA polymerase II transcription subunit 19a
Arabidopsis
MEPERLKFGGPRELCGAADLISQFKLVQHHEFFCKKSLPVSLSDSHYLHNVVGDTEIRKGEGMQLDQLIESISQSRETNIRIQPFDIDELQESFQLNDMTPVELPPAEKGAPTIPSKSKSESKDRDRKHKKHKDRDKDKDREHKKHKHKHKDRSKDKDKDKDRDRKKDKNGHHDSGDHSKKHHDKKRKHDGDEDLNDVQRHKKNKHKSSKLDEVGAIRVAG
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Q9FMP0
Q9MIY1
NU4M_DANRE
NADH dehydrogenase subunit 4
Danio
MLKVLIPTIMLFPTIWLSSSKWLWTTTTMNSFLIAFISLTWLKWTSDTGWNASNSYMAADPLSTPLLVLTCWLLPLMILASQNHINSEPVNRQRMYITLLASLQTFMIMAFGATKIIMFYIMFEATLIPTLIIITRWGNQAERLNAGTYFLFYTLAGSLPLLVALLLLQQSTGTLSMLVLQYSDPLLLNSWGHKIWWAGCLIAFLVKMPLYGMHLWLPKAHVEAPVAGSMILAAVLLKLGGYGMMRMMVMLDPLSKQLAYPFIILALWGVIMTGLVCLRQTDLKSLIAYSSVGHMGLVAGGILIQTPWGFTGAIILMIAHGLTSSALFCLANTSYERTHSRTMILARGLQMVLPLATVWWFIANLANLALPPLPNLMGELMIITALFNWSPWTIIITGMGTLITANYSLYMFLTSQRGSIPEHITNLSPSHTREHLLMTLHLIPIILLMLKPELMWGWCN
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Q9MIY1
Q5NVI3
RED_PONAB
IK factor
Pongo
MPERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPIDVDKGPGSAKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGVEVKRPKY
Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1.
Q5NVI3
Q750W3
RKM5_ASHGO
Ribosomal lysine N-methyltransferase 5
Eremothecium
MLQLCPLDEDTLYTHVYERYVELDRHAETLAQDLGIHASDAETLVVDIAPAQPTKSSDTYSLTVSQSLASLRSSTVNNNSTTGYVLWSGTPFFLCWLLYAPSAAPLRDGGRVPVTDSAAQFLQLPPLFSAPARPVCVVELGSGAAGVAAIVLANYVDRYLVSDQKAILKPLRANLLANISEVSRRTVCSKQTPELSSNRRTPARCELELIALDWERIATVPAALRPTDAAHVHVLALDVVYNDFLIPPLLTAIKRLLRWYADEHAVKATAYVLVHLRAQDILQTFLEHAIIDLRLRCYYMDEERLRSSRFALYYVTL
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates 60S ribosomal protein L1.
Q750W3
Q7AP31
FLOA_LISIN
Flotillin-like protein FloA
Listeria
MTMIGPIIIAVLIIIFLIVFFTLVPVGLWISALSARVPVGLGTLIGMRLRRVVPSRVVKPLIKAVKAGLDLEVNQLESHYLAGGDVDNTVDALIAAHRANIELDFSRAAAIDLAGRDVLEAVQTSVTPKVIRTPEFTGVAQNGVEVKVITQITVQSNIERIVGGAGEDTVIARVGEAVVSTVGETREHTDVLENPNSISKKVQEQGLGDGTAYTILSIDIAEMRIGDNIKAKLDIEKANADMEVAQAAASKRKAEAIALEQENRAAVVAAEAEVPRALSRALEEGNLGVMDYYKMENVQSDTAMRESIAHEDEK
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
Q7AP31
A7INJ8
LEXA_XANP2
LexA repressor
Xanthobacter
MLTRKQYDLLRFIHERLKETGVPPSFDEMKEALDLRSKSGIHRLITALEERGFIRRLPNRARALEVVRLPDSVAPGLATPRSASRGFSPSVIEGSLGKVRPAADDDEGAGQVVTVPVMGRIAAGSPISAIQTRSHTLNIPPEMLGSGEHFALEVRGDSMIEAGILDGDTVLIRKCDTADTGDIIVALVDDEEATLKRLRKKGASIALEAANPAYETRIFGPDRVRIQGRLIGLMRRY
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
A7INJ8
B2U9W0
PURA_RALPJ
IMP--aspartate ligase
Ralstonia
MSAPAVSQGRNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLIIGGKKTILRLIPSGIMRDGVACYIGNGVVLSPEALFKEIDELESAGVQVQNRLRISEATNLILPYHVAIDKAREAKRGAAKIGTTGRGIGPAYEDKVARRGLRVQDLFDPAYFAERLRENLDFHNFVLTQYLNHPALDFQQTLDEMLSYAGRLAPMVTDVSAELFAANAAGKNLMFEGAQGTLLDIDHGTYPFVTSSNCVAGNAAAGAGVGPGQLHYILGITKAYCTRVGSGPFPSELYDADNPARQDPIGVRLANVGKEFGSVTGRPRRTGWLDAAALRRAIQINGVSGLCMTKLDVLDGLETLKLCVGYMLDGKQIDILPRGSDAVARCQPIYEEFPGWNTSTFGLKEWDALPQTAQAYLKRVEEVAGIPIAMISTGPDRDETILLRHPYKD
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
B2U9W0
P22314
UBA1_HUMAN
Ubiquitin-activating enzyme E1
Homo
MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR
Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system . Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP . Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites .
P22314
B9K884
EFTU_THENN
Elongation factor Tu
Thermotoga
MAKEKFVRTKPHVNVGTIGHIDHGKSTLTAAITKYLSLKGLAQYVPYDQIDKAPEEKARGITINITHVEYETEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVEVPYMIVFINKTDMVDDPELIELVEMEVRDLLSQYEYPGDEVPVIKGSALKALEAPDDPNHEAYKPIQELLDAMDNYIPDPQRDVDKPFLMPIEDVFSITGRGTVVTGRIERGRIRPGDEVEIIGLSYEIRKTVVTSVEMFRKELDEGIAGDNVGCLLRGIDKDEVERGQVLAAPGSIKPHKRFKAEVYVLKKEEGGRHTPFTKGYKPQFYIRTADVTGEIVGLPEGVEMVMPGDHVEMEIELIYPVAIEKGQRFAIREGGRTVGAGVVTEVIE
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
B9K884
P96095
HCP_ACIFI
Prismane protein
Acidithiobacillus
MMFCYQCEQTTRSPAGIGCTSEPGTCGKDEATAVLQDILTHLMKGIASMRAGRAMGVADRRTDDFIFYGLFTTLTNVNFTATRFVHLIQEASKRRERIKLLYEEAAREQGKTPEILSGPALFQPADSLEQLLRQAPSVAINADVEHLGSDVIGARALILYGMKGVALIAQHARVLGYQSDEVMPQAEEILDYLASNPTDLDEMLEESLEVGRLNLKVMELLDVANTDSFGAQEITSVRISPIQGKAILVSGHDLHDLKQILEQTKDQGINVYTHGEMLPANAYPLLKAYPHLAGNLGGAWQDQQREFADFPGPIVMTSNCIIEPGRSYKNRIFTLGPVGWPGVRHIDNGDFTPVIQAAKALPGFTADAKEQRITIGFGHHTLLGVADKIVDAVKHGDIRHFFLVGGCDGVSPARNYFTEVADNAPADSVVMTLGCGKYRFNKHEFGDIGGIPRLLDIGQCNDAHSAIRVAGALAEAFNCGVNDLPLSIMLSWFEQKATAIHLSLLALGIKGIKLGPTLPAYLTPTLVQKLQSRFDLDLDLIGEAQADLQAALAHTA
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
P96095
B7KHC2
TRMD_GLOC7
tRNA [GM37] methyltransferase
Gloeothece citriformis
MRFDIITLFPDFFTSPLQSGLLGKALDKQIAQVNLVNPRDFALDKHHRVDDEPYGGGVGMLLKPEPIFAAVESLEILPRREVVLMTPQGQPLSQPILRELATDFDQLVLICGHYEGVDERVTQYLVTREISLGDFVLTCGEIPALTVLNGVIRLLPGTVGKEESLKLESFEADLLDYPQYTRPALFRDWEVPAVLRSGNHQAIEQWRKQQQIERTKERRPDLWEKWTINNG
Specifically methylates guanosine-37 in various tRNAs.
B7KHC2
P31353
PMM_CANAL
Phosphomannomutase
Candida
MSFANKQDPKTLVLFDVDGTLTPARLTISEEMKKTLEKLREKVVIGFVGGSDLSKQVEQLGPNVLNDFDYCFSENGLTAYKLGKELASQSFINWIGNEKYNKLVKFILRYLSDIDLPIRRGTFIEFRNGMINVSPIGRNASTQERNDYEKFDKQHHIRETMVEALKKEFPDFGLTYSIGGQISFDVFPTGWDKTYCLQHVEDEHFENIHFFGDKSYKGGNDYEIYNDPRTIGHAVNSPDDTIRILNETFKLQ
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
P31353
B7KHD0
FMT_GLOC7
Methionyl-tRNA formyltransferase
Gloeothece citriformis
MKVVFFGTPQFAVPSLERLLEHSDIDVVAVVTQPDKPRGRGKQLIPSPIKKVALDHQIPIWQPKRVKKNAQTLTKLRETNADAFAVVAYGQILSAEILQMPKLACINVHGSILPKYRGAAPIQWSIYHGETQTGITTMLMDEGMDTGAMLLKAYTPIQLLDNADKIATTLANQGADLLIETLLKLEQGELNPESQNSELATYAPLIQKEDYLINWTRHALQIHNQVRGFYPNCFTTFREQPLKILATAPLGEAYWEHLPSNIAQKIQPQWTTLSSLTSSPGEVVNLIKNLGPIVQTGEGLLLLLQVQLSGKRPQSGWDFVNGTRLSVGEKFLMV
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
B7KHD0
A5FLE3
HEM11_FLAJ1
Glutamyl-tRNA reductase 1
Flavobacterium
MENNNVPKHLYFYSVGLSYKKADAEVRGQFSLDAVAKTRLLEQAKNDGIESLLVTSTCNRTEIYGFAEHPFQLIKLICDNSNGSVDAFQKVGFVYKNQEAINHMFRVGTGLDSQILGDFEIISQIKTSFTHSKSMGLANAFMERLVNAVIQASKRIKTETEISSGATSVSFASVQYILKNVEDISNKNILLFGTGKIGRNTCENLVKHTKNEHITLINRTKDKAEKLAGKLNLIVKDYSELHLELQKADVVVVATGAQNPTVDKAILNLKKPLLILDLSIPKNVNENVEELEGVTLIHMDYLSQLTDETLENRKLHIPAAEAIIEEIKEEFVTWMKGRKFAPTINALKEKLNAIKASELDFQSKKIADFNEEQAEIISNRIIQKITTHFANHLKDDDTMVDESIEWIEKVFKIKAS
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
A5FLE3
A1AU58
DDL_PELPD
D-alanylalanine synthetase
Pelobacter
MNDIRSRKIAVLMGGLSAEREVSLASGAAVCQALVARGFDALSVDVARDLPLVLSREGIGAAFIALHGRYGEDGCVQGLLELMAIPYTGSGVLASALAMHKLYSKQAFVSAGILTAPFHHFRRGERVSLSHLSFGLPLVVKPVQEGSSVGISIVKEESQLAAAVKLAFRHDDEILVEQFIKGQEVQVGILDDRPMGAIEIVSRNEFYDFEAKYTDGMAEHFFPARLEKGLYEEALRVGLAAHHALGCRCYSRVDLLVTPAGECYVLEVNTLPGMTALSLLPEIAAKGADLPFEELVERIILSADLSVKTG
Cell wall formation.
A1AU58
Q85FW3
RK3_CYAM1
50S ribosomal protein L3, chloroplastic
Cyanidioschyzon
MSLLMSLLATKIGMSQLFDEKGNALPVTWVKSGVHEVIDHRTPEKHGYTALVVRYQHWIREFRVKHLSAYPIGRRLDLSTCFQIGQKVSVKAKTIGKGFAGYQKRHHFARGPMSHGSKNHRQPGSIGAGTFPGRVFPGTRMAGRLGGNFCTIKGLEILQIQNDQMALKGAVPGKVGNLLRIE
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Q85FW3
Q91V13
LEAP2_MOUSE
Liver-expressed antimicrobial peptide 2
Mus
MLQLKLFAVLLTCLLLLGQVNSSPVPEVSSAKRSRRMTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE
Has an antimicrobial activity.
Q91V13
Q8P1C8
ENGB_STRP8
Probable GTP-binding protein EngB
Streptococcus
MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSFINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAEWGKMIEEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV
Necessary for normal cell division and for the maintenance of normal septation.
Q8P1C8
A4FYA5
PSB_METM5
Proteasome core protein PsmB
Methanococcus
MISNSEYHKEYMKGTTTVGLLCKDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIAGSVGDAQSLIRIISAEAKIHKMRTGNNMTPLSCTTLISNVLHGNRHYPLLTQLILGGYDLINGAKLFSLDPVGGINEESSFTATGSGSPTAYGVLEAEYRSDVTIDKGLLVAVKALSSAMQRDAYSGNGISLAHINKDGVKLYSDAEIEGFLKKINKKR
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
A4FYA5
P26223
XYNB_BUTFI
1,4-beta-D-xylan xylanohydrolase B
Butyrivibrio
MNLKTAYEPYFKIGAAISRWNLHTPAHTKLLAEQFNSFTCENDMKPMYYLDREANKKDPEKYNLSPALTFENAIPYLEFAKDNKIAMRGHTLVWHNQTPKWFFCERYNENFPMADRETILARLESYIHGVLDFVQTNYPGIIYAWDVVNEIVDEGAFRKSIWTETVGEDFFIKAFEFARKYAAPEVSLFYNDYETAQPWKRDFILEKVLGPLIDKKLIDGMGMQSHLLMDHPDISEYRTALEMYGSTGLQIHITELDMHNADPSEESMHALATRYQEFFQTYLDAKKSGKANITSVTFWNLLDENSWLSGFRRETSYPLVFKGKCEAKEAYYAVLKAAVSDDSIDKWVPDYSEEDYKLQGMPTPDIKRFRENIWQENEYNYEASYGFIPNLFAYLHNDDVKRDCMLVIPGGGYCMCCSHEGELAAMEFYNRGMNAFVLSYTTDITMSVPLHKQPLEDISRAVRFIRKNASKYNIDGKKLVIMGFSAGSHVCGSLAVHFDDVKDNNPEYADISGRPDGVILSYPVITTGRYTHADSVRTLLGANPTDEELTYFSLEKQVKDNTPPCFIWQTEEDSVVPVENSYLFANALREKKIPFAHYVFPRGFHGLTVANDEFFSGWSGGEYSMEQTMRARFAV
B.fibrisolvens is located in the rumen of ruminant animals, where it contributes to the animal's digestion of plant material by hydrolyzing hemicellulose with its xylanases.
P26223
Q5LNP2
ATPE_RUEPO
F-ATPase epsilon subunit
Ruegeria
MANTMQFDLVSPERLLASLQVSAVQIPGADGDMTAMPDHAPTITTLRPGVLKVEGPEGTSEYLVTGGFAQIGADSLSVLAEKAIPVTEVTRAHLDELIAEARSSHEAAKGQEHTSVVDDAAKLLADMEALGTHMGL
Produces ATP from ADP in the presence of a proton gradient across the membrane.
Q5LNP2
Q9LE63
MY106_ARATH
Transcription factor NOEK
Arabidopsis
MGRSPCCDKAGLKKGPWTPEEDQKLLAYIEEHGHGSWRSLPEKAGLQRCGKSCRLRWTNYLRPDIKRGKFTVQEEQTIIQLHALLGNRWSAIATHLPKRTDNEIKNYWNTHLKKRLIKMGIDPVTHKHKNETLSSSTGQSKNAATLSHMAQWESARLEAEARLARESKLLHLQHYQNNNNLNKSAAPQQHCFTQKTSTNWTKPNQGNGDQQLESPTSTVTFSENLLMPLGIPTDSSRNRNNNNNESSAMIELAVSSSTSSDVSLVKEHEHDWIRQINCGSGGIGEGFTSLLIGDSVGRGLPTGKNEATAGVGNESEYNYYEDNKNYWNSILNLVDSSPSDSATMF
Functions as a repressor of epidermal cell outgrowth and negatively regulate trichome branch formation . Acts as both a positive and negative regulator of cellular outgrowth. Promotes both trichome expansion and branch formation . Coordinately with WIN1/SHN1, participates in the regulation of cuticle biosynthesis and wax accumulation in reproductive organs and trichomes. Functions in cuticle nanoridge formation in petals and stamens, and in morphogenesis of petal conical cells and trichomes . May play a role in the regulation of cuticle formation in vegetative organs .
Q9LE63
Q09504
YQI2_CAEEL
Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2
Caenorhabditis
MVRYSKLAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDPFVLSEAAEMVYKCSTGVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPDPDFSVSLKIRINHDIEKTVDLCRKAEAAGVTHLTVHGRTPSQRAEPIDIQALRIVKDSVSVPIIANGGITTREEALFLAEQTGVDGIMAANGLLDNPALFAGHEHTPSDCVENFMRLSREYGLDWLLYHQHLQYMLRPVFSAQQRRVFNELNGRLAIDHFLNNLLDI
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Q09504
A9MCK4
DADA_BRUC2
D-amino acid dehydrogenase
Brucella
MQITILGSGVIGVTTAYYLAKLGHEVTVIDREEGPAPETSFANAGQVSPGYASPWAAPSIPLKAAKWLFQKHAPLILRLTTDPVQYRWLLQMLANCTDSRYKINKTRMVRVAEYSRDCLIELRKDTGIEYDQRSQGTLQLFREQYQLDGIGKDIEVLRQDGVPFEVLDRDGCVNVEPALAHAKDKFVGGLRLPNDETGDCFKFTNALAKIAEGLGVKFRFGVNIKSLLMSGGKISGVETSEGIVTAERYVVALGSYTPALIKALGLNAPIYPVKGYSITAPIVDESRAPVSTVLDESYKIAITRLGDRIRVGGMAEVSGFTDDLPAARRATLDLSVTDLFPGGDLKAATFWSGLRPMTPDSTPIIGGTRYDNLFINAGHGTLGWTMACGSGRLLADLISGNKADIRADDLGIARYN
Oxidative deamination of D-amino acids.
A9MCK4
Q97SQ2
DPO3_STRPN
DNA polymerase III PolC-type
Streptococcus
MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFHFVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGPCASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQVEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKAAAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSMQKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPEGERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKAGIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKMYKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVAHNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEHHHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKNQVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVDAAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGNVHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFLGEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPLPDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGITEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLGFDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERDYGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIEAMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLDLYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSSTLVEKMDEMGILGNMPEDNQLSLFDELF
Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
Q97SQ2
P96065
PHNV_SALTY
Putative 2-aminoethylphosphonate transport system permease protein PhnV
Salmonella
MLIWSPKGRAAAGVVASVLFIVFFFLPLAVILMSSLSQQWNGILPSGFTLNHFVNALHGAAWDALLASLTIGFCASLFALLCGVWAALALRQYGVKTQKWLSMVFYLPSAIPSVSVGLGILVAFSQGPLQMNGTLWIVLTAHFVLISAFTFSNVSTGLARISADIENVASSLGASPWYRLRHVTLPLLMPWMMSALALSLSLSMGELGATMMIYPPGWTTLPVAIFSLTDRGNIADGAALTIVLVAITLLLMMKLERIAKRLGQK
Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane.
P96065
O46427
CATH_PIG
Cathepsin H light chain
Sus
MWAVLSLLCAGAWLLGPPACGASNLAVSSFEKLHFKSWMVQHQKKYSLEEYHHRLQVFVSNWRKINAHNAGNHTFKLGLNQFSDMSFDEIRHKYLWSEPQNCSATKGNYLRGTGPYPPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDEEAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
Important for the overall degradation of proteins in lysosomes.
O46427
A8I3B5
RNC_AZOC5
Ribonuclease III
Azorhizobium
MSETQDFAALEARLGHSFADRSHLVLALTHISSVKGQAVRVRSYQRLEFLGDHVLGSVVSHMLYAAFPKAEEGELSRRLAELVREEACAEVAQDMGLGPYLRLGPGEAQSGARQRRAILADVAEAVVAAVYLDGGYEAASALVERFWRGRLEAPRRPLRDPKTVLQEWAQARGLPPPVYRDVERSGPDHAPRFRVAVDLPGLECAEAEGGSKQTAQKAAASAFLAREGVVTESGE
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
A8I3B5
P46161
DEFB3_BOVIN
BNDB-3
Bos
LALLFLVLSAGSGFTQGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
Has bactericidal activity. Active against E.coli ML35 and S.aureus 502A.
P46161
Q6GFY8
RS4_STAAR
30S ribosomal protein S4
Staphylococcus
MARFRGSNWKKSRRLGISLSGTGKELEKRPYAPGQHGPNQRKKLSEYGLQLREKQKLRYLYGMTERQFRNTFDIAGKKFGVHGENFMILLASRLDAVVYSLGLARTRRQARQLVNHGHILVDGKRVDIPSYSVKPSQTISVREKSQKLNVIVESVEINNFVPEYLNFDADSLTGTFVRLPERSELPAEINEQLIVEYYSR
With S5 and S12 plays an important role in translational accuracy.
Q6GFY8
Q9UPY8
MARE3_HUMAN
RP3
Homo
MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGGHETDAQILELNQQLVDLKLTVDGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY
Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton . Promotes microtubule growth . May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes . Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement . Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules .
Q9UPY8
Q7SHZ2
GATA_NEUCR
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
Neurospora
MSARIGRLRGLCLRHVSSTRQTSPIQRRSLNQFISRVQQHDQPALEQRQFRLAVKDNIATVSPNSEEETPLTTTCGSNFLANYRSPFEATIVSQLRSRGALLVGKTNLDEFGMGSHSVHTAFGAVAQEGEHEQQAVKHSAGGSSGGSAVAVATGEADIALGTDTGGSVRLPAGYTGVVGFKPSYGMLSRYGVVPYANSLDTVGLLAKEVRPIAELILGGADKVTRGLWAEHDPLDPTSLSHGARRRCASQRDCYTGPLPKDPYPLKNLKFGLPLEYNITELSPSIRHSWSAAAAKLQSLGARLVPVSLPSTRHALSAYYVIAPAEASSNLAKYDGIRYGTRFTSPTESDAAISEGPEGREEEEEGILYARARTAGFGDEVKRRILLGAYTLSSAAMDNYFLKAQKVRRLVRRDFNRVFALPNPLLDKPERFELSELPETVGLEDKWGPTEVDFLLCPTAPTTAPRLDEVLSEEEKDPVSAYMNDVFTVPASLAGLPAISVPMRVEDKEGAGMAGLQLIGQYWDDARLLAVAETVADVVREEL
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Q7SHZ2
C5CJH0
THIG_VARPS
Thiazole synthase
Variovorax
MTTASAIPDNDPLVLYGQTFHSRLLLGTARYPSPDLLEAAVKRAKPAMLTASLRRQSASPGASDSGNGFWELLRRLAVPVLPNTAGCHSVQEVIATAQMARELFDTPWIKLELIGDDYTLQPDTLNLVDAASQLIRDGFQVLPYCTEDLVLCQRLVDVGCQAVMPWAAPIGTGRGPVNPYALQLLRERLSVPMLVDAGLGLPSHACQVMEWGYDGVLLNTAVALAQDPVSMAGAFADAVQAGRAAHRAGAMAAQDSAQPSTPVLGTPFWHHAP
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
C5CJH0
P63085
MK01_MOUSE
Mitogen-activated protein kinase 2
Mus
MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
P63085
Q0ID34
RF1_SYNS3
Peptide chain release factor 1
unclassified Synechococcus
MDTTTLISRLEAASSSFHNLERQLADPDVAADPQRLETIARERSRLEPLVLDYTSLQKVEAEQVQAKSLLKESRGDAAMEELAQQELQELDRHHADLIQRITLALLPKDPRDERSVMLEIRAGAGGDEACLWAGDLARMYERFSSRRGWSVTPVSANEADLGGYKELILSVKGDAVFSELKFEAGVHRVQRVPSTESQGRVHTSTATVAVMPEADPVEVQIDPRDLDISTARSGGAGGQNVNKVETAVDLMHKPTGIRVFCTQERSQMQNRERALEILRAKLYERQLAEANASERSARRSQVGTGDRSEKIRTYNAKDNRMTDHRLGRNFSLDPVLEGQMDDVIDACIAEEQRGKLADLSEQAD
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
Q0ID34
B3EK39
PYRG_CHLPB
UTP--ammonia ligase
Chlorobium
MARPKNVKHIFVTGGVVSSLGKGILSASLGLLLKSRGLRVAIQKYDPYINVDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFLDEPTSQASNLTMGRVYKAVIDKERQGEYLGGTVQVVPHVIDEIKAKMNELAKNANLDVLITEIGGTIGDIESLPFLEAMRQLKLDLGTKNLLNIHLTLVPYIKAACEMKTKPTQHSVKMLLETGIQPDILVCRSEKPLSREIKNKVGHFCNLHEADVIGLSDCETIYGVPIMLLDEQLDKRVLKKLGIKKFQDPELSYWTEFCDKVKHPEDGEVTIAVCGKYTEYPDAYKSILESFVHAGAVNNVKVTVRFIRSEDAEESGCDIATAMKDVHGLLVAPGFGDRGIEGKISFIRYARENNIPFLGICLGMQCATIEFARNVCGLSEANSTEFSKRCRQPVIDLMEHQKKVKEKGGTMRLGSYPCILKEDTIANKAYGKFLINERHRHRYEFNNEYRELLEQNGMLFSGTSPNGDLVEIIEISGHPWFVGVQFHPEYKSRVRSAHPLFVGFVAAAKAFAFGDRQLSFEPDTLPLGEPERTLEG
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
B3EK39
B2S679
RL3_BRUA1
50S ribosomal protein L3
Brucella
MRSGVIAQKLGMTRVYNDAGEHVPVTVLRMENCHVVAQRTVEKNGYTAVQLGVGMAKVKNTSKAMRGHFAKAEVEPKAKLAEFRVSPDNLLEVGVEITAEHFVAGQKVDVTGTSIGKGFAGVMKRHNFGGHRASHGNSITHRSHGSTGQRQDPGKVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRGLILVRGAVPGSKGAWILVRDAVKASLPENAPKPAGLRAGAKAEAAATEGGE
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
B2S679
B3PK52
RL6_CELJU
50S ribosomal protein L6
Cellvibrio
MSRVAKSPVEVPAAVTVTLNGQSLSVKGGKGTLALEVHANVEVKHEGNVLTFTPRDGAKQSDALAGTTRALVNNMVVGVSQGFEKKLTLVGVGYRVKAEGNTVNLSLGYSHPVNYVLPQGVSVETPSQTEIVLKSADKQLLGQVAAEIRAFREPEPYKGKGVRYSDEVVLRKEAKKK
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
B3PK52
B6I9D2
TRHO_ECOSE
tRNA hydroxylation protein O
Escherichia
MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKVTRDALYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYDFDPALEGLRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNKSRGRLNTTLGIPDPTE
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-carboxymethoxyuridine (cmo5U) biosynthesis. May be part of an alternate pathway, which is able to bypass cmo5U biogenesis in a subset of tRNAs under aerobic conditions.
B6I9D2
A0A2K1J5A5
SOK3_PHYPA
Protein SOSEKI 3
Physcomitrium
MARGEDSSSVQVLYQLSWDGKLEHPHMIEVHYPPNQGGLRLRDVKKRLTTLRGHGINDSFSWSSKRNYKNEFIWNDLCDDDVIQPLRGSGEYVLRASELFDTFTNKPWEHPSKHSNERMQSSRTMSVDNVTLQQGLINVKLHSGALAREDDQPSGEKLCCSGRRSCINLEDCSSKGVAIDIPKNLQNLSVDQETIDVEKSDFCLSSSDNEVSPRLKTAADCITPVKDVGLVVMTRSTTVHGLHTPAPRSLTSPTEPPFSPGSAKRMWKKEIRKSLFRTSRNSSNVNPVLSGENAALDVDVPPITLSTQEDVSFWRDGRSKSASPSSLNELREVQNEKEKEAEQSTSQLIRLLWARWTGGSSKGKRTPQSTCEDPLPKSPEAKQMPRSRTKTPCKEIRSTNHIAGSLPVTCPSPAVDNKAHSSLDRQEIPPQEECKNRPSPMTLQSCEEITSPVTEIEQDVEIGDIKAIVEEQASNKFPEPEFQQNLRTEQIVLSVQIPDLHIDALDSPTSDTQGSPAEADIPKSATARVKTSNSLPRVKTTTSPKPLPPGFHKGTNDTKPVQIITPRRTPRTSIPLASPPPLVRTFNRVSVRSLSSIAAITLSPENDSAASNLSPENPIVKKRINFRERDEMPLIPGLTTLDWEKALQEAVTDCLPPPNFREILQECSTCGRTFKPDSLQVHMRGCHPPQYARAFSARASPHVVRSRAS
SOSEKI proteins locally interpret global polarity cues and can influence cell division orientation to coordinate cell polarization relative to body axes.
A0A2K1J5A5
Q13UB5
ANMK_PARXL
AnhMurNAc kinase
Paraburkholderia
MAQDPADGVYFGLMSGTSMDGVDGVAVRFAQGKPSVVLAEAFVGFAAGLRDALFALQQPGDNEIEREALAANALATRYAVCCHDLLHNSRVPAAEVRAIGVHGQTVRHRPEKGYTRQINNPALLAEMMHIDVIADFRSRDVAAGGQGAPLVPAFHATVFGAKNETRVVCNLGGISNITILNATGSVRGFDCGPANALLDEWAQRHLGKPFDENGHFAAGGQVDRTLLNALLDEPFFGQQPPKSTGRDLFNADWLDAKLPPFAALDHADVQATLVALTAVTVAREIERHASDAKAVYVCGGGARNPEILKALQQALEDSGVSGVPVMTTDALGVPPSQVEPLAFAWLAMRCVARLPGNLPAVTGASAERVLGAIYPR
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
Q13UB5
Q0C0Y0
RF2_HYPNA
Peptide chain release factor 2
Hyphomonas
MSAEIRSLIEKIESSAALLRRRLDWDTATKRLDELTALSERPNFWDDPQEAQAMMRERQKLADGIALVQTLEKDVADAPELMELAEGDASMLADLEATLRRAAARAAEAELAALLSGEADGNDCYLQINAGEGGTESQDWASILRRMYVRWAEKRGYGVELLDERDGEEAGIKSATLQIKGENAYGWLKSEQGVHRLVRISPFDSSARRHTSFSSVAVSPVIDDKIDVEINPSDVRTDTYRASGAGGQHVNRTDSAVRLTHIPTNTVVQCQAGRSQHQNRDEAWKMLRSKLYELELQKRRAVADAQYADKSAIGFGHQIRSYVLQPYQMVKDLRTEVETSDTSGVLDGDIDRFLSAALAASVSKDQDA
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
Q0C0Y0
B8DCW3
RHAD_LISMH
Rhamnulose-1-phosphate aldolase
Listeria
MTKDIMDAVFIKEMAKTTSNLYRLGWDERNGGNITYLLDEKEVVEYLDVKQIIRTIPMDFDGEKLAGKYFLVTGSGKYFKNVEEAPAVNLGVIQVSEDGKAVHLLWGYTDGGLPTSELPAHFMSHIARLSVDPENRVVMHCHATHLLAMTFTHELTEREFTRTLWQMCTECLVVFPEGVGIIPWLVPGTNEIGEATSEKMKENRLIVWPHHGIYGAGKSMDETFGLIETAEKAAEVYTIVMSQGGIKQAITDEQLKALGERFSVEAKAGYLNN
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
B8DCW3
Q21MH7
RSMH_SACD2
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Saccharophagus
MNESPHFSVLLQESVESLVVDPAGTYVDGTFGRGGHSRAILAKLGPEGKLFGIDKDPEAVAVGKALEAEDSRFRIVHGSFADLKHIDLLQADFAAGGLSGVLVDLGVSSPQLDVAERGFSFMNDGPLDMRMNTEAGMTAAEWINTAKQEDIAQVLWEYGEERFSRHMAKAIVERREIKPFTRTHDFAEVVKAANRKWEKGKHPATRAFQAVRIFINRELEDLRQLLDDSVSVLAPGGRFVVISFHSLEDRMVKRFFRDQSMGKQFPKGLPVTEEMKKQNLKIIGKALKAGDTELTQNIRSRSAVMRVGERLG
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
Q21MH7
Q17VC7
CH10_HELAH
Chaperonin-10
Helicobacter
MKFQPLGERVLVERLEEENKTSSGIIIPDNAKEKPLMGVVKAVSHKISEGCKCVKEGDVIAFGKYKGTEIVLDGTEYMVLELEDILGIVNAGSCCHANSHDHKDHKHAEACCHDHKKH
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
Q17VC7
P44466
DACA_HAEIN
Penicillin-binding protein 5
Haemophilus
MLKRTTKIAFLSSFVALSAFSVSAEDMQFGVTPPQITAQTYVLMDYNSGAILTALNPDQRQYPASLTKMMTSYVVGVALKQGKIHNTDMVTIGESAWGRNFPDSSKMFLDLNTQVSVADLNRGVIVVSGNDATVALAEHISGNVPNFVETMNKYVQQFGLKNTNFTTPHGLDDPNQYSSARDMAIIGAHIIRDLPEEYKIYSEKNFTFNKIKQANRNGLLWDKTINVDGMKTGHTSQAGYNLVASATTSNNMRLISVVMGVPTYKGREVESKKLLQWGFANFETFKTLEAGKEISEQRVYYGDKNSVKLGALMDHFITIPKGKQSEVKARYELADKNLQAPLVKGQVIGKVVYQLDGKDIASANLQVMNDVGEAGIFGKLWDWLVLTVKGLFS
Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
P44466
Q3KKS6
MIAA_CHLTA
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Chlamydia
MSSSSSSGAATGFAVCSDPQKSFSKMFKRTVILLAGPTGSGKTAVSLKLAPLVDGEIISVDSMQVYQGMDIGTAKVSLADRKEVPHHLIDVCHVQESFNAVDFYYHAVQACQDILSRNKVPILVGGTGFYFHTFLSGPPSGPSPDFVLREQLTLEAQERGISALYQELELLDPVYAATITKHDKNKIIRALEIIRKTGSKVSSYAWQSTVNESKEYHCRGWLLSPDPELLRHNILERCDQMLEEGLLDEVQALLAAGIKGNSSASRAIGYREWIEFLDLGSPPDLFEITKQKFITNTWRYTKKQRTWFKRCSLFRELRPMGMTLDDMAKKIAQDYFLCG
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
Q3KKS6