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<|newrecord|> nctId: NCT06298656 id: ILBS-ACLF-17 briefTitle: Acute hemodynamiC Response To Carvedilol Predicts Survival in ACLF Patients overallStatus: NOT_YET_RECRUITING date: 2024-03-10 date: 2026-02-28 date: 2026-02-28 date: 2024-03-07 date: 2024-03-07 name: Institute of Liver and Biliary Sciences, India class: OTH... |
<|newrecord|> nctId: NCT06298643 id: CA056-1094 briefTitle: Real-World Practice Patterns and Outcomes of Lower-Risk Myelodysplastic Syndrome Patients in Japan overallStatus: ACTIVE_NOT_RECRUITING date: 2023-12-22 date: 2024-12-31 date: 2024-12-31 date: 2024-03-07 date: 2024-03-07 name: Bristol-Myers Squibb class: INDUS... |
<|newrecord|> nctId: NCT06298630 id: 2022-LTF-BRL-101 briefTitle: Long-term Follow-up Study of BRL-101 for TDT overallStatus: NOT_YET_RECRUITING date: 2024-12-08 date: 2038-08-20 date: 2038-10-15 date: 2024-03-07 date: 2024-03-22 name: Bioray Laboratories class: INDUSTRY name: First Affiliated Hospital of Guangxi Medic... |
<|newrecord|> nctId: NCT06298617 id: RC 27.1.2024 briefTitle: Systemic Inflammatory Indices as a Non-invasive Grading Modality for Endometriosis overallStatus: COMPLETED date: 2023-01-01 date: 2023-07-30 date: 2023-12-25 date: 2024-03-07 date: 2024-03-12 name: Benha University class: OTHER briefSummary: Endometriosis (... |
<|newrecord|> nctId: NCT06298604 id: IECED-12112023 briefTitle: Motorized Fine Needle Biopsy vs Standard Needles overallStatus: RECRUITING date: 2023-12-09 date: 2024-10-09 date: 2024-12-09 date: 2024-03-07 date: 2024-03-22 name: Instituto Ecuatoriano de Enfermedades Digestivas class: OTHER briefSummary: Recent improve... |
Given the advancement mentioned, the investigators aim to compare the performance of the mFNB with the standard needle during the acquisition of endoscopic ultrasound (EUS)-guided pancreatic and liver specimens through a prospective, interventional, single-center trial. The study will consist of two groups of patients:... |
<|newrecord|> nctId: NCT06298591 id: atrophic scar treatment briefTitle: The Efficacy of Combination Therapy in Atrophic Scars overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2027-03-15 date: 2027-03-15 date: 2024-03-07 date: 2024-03-07 name: Assiut University class: OTHER briefSummary: There are more than 100... |
Atrophic scars are dermal depressions, which are commonly caused by the destruction of collagen following inflammatory process. This permanent disfiguring sequelae correlates with the duration of pathology, severity of lesion, and delay in therapy (3). |
Treatment of atrophic acne scars remains a therapeutic challenge, yet there is no standard option as the most effective treatment (4). A range of possible options has been investigated including surgical techniques (subcision, non-ablative laser treatment, resurfacing techniques (ablative laser treatment, dermabrasion)... |
Ultrasound is a unique non-invasive and non-radiating medical imaging tool in the investigation of dermatological diseases by providing detailed anatomic and physiologic data of skin lesions and deeper soft tissue changes. Lesion size in three dimensions-lengths, width, and depth, morphology, the detailed anatomic info... |
<|newrecord|> nctId: NCT06298578 id: Mobile Based Application briefTitle: The Utility of Mobile Based Application for Patient Reported Outcome Measures In Patients With Acetabular Fractures : A Randomized Clinical Trial overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-12-01 date: 2026-01-01 date: 2024-03-0... |
The secondary objective is to Improve quality of life and early prediction of the complications. conditions: Acetabular Fracture studyType: OBSERVATIONAL observationalModel: ECOLOGIC_OR_COMMUNITY timePerspective: PROSPECTIVE count: 126 type: ESTIMATED measure: percentage of missed follow up data in both groups postoper... |
<|newrecord|> nctId: NCT06298565 id: ARGX-113-PASS-2208 briefTitle: A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2034-06 date: 2034-06 date: 2024-03-07 date: 2024-03-07 name: argenx class: INDUSTRY briefSummary: Th... |
<|newrecord|> nctId: NCT06298552 id: ARGX-113-2308 id: 2024-511796-15-00 type: OTHER domain: CTIS number briefTitle: A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis acronym: ADAPT SERON overallStat... |
Study will consist of: |
* Screening |
* Part A: participants will be randomized to receive either efgartigimod IV or placebo |
* Part B: participants completing part A will receive open-label efgartigimod IV conditions: Generalized Myasthenia Gravis studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 110 type:... |
<|newrecord|> nctId: NCT06298539 id: 21C308 briefTitle: Auditory Sensory Attenuation in Obesity acronym: Ud_SA_OB overallStatus: ACTIVE_NOT_RECRUITING date: 2023-03-01 date: 2024-12-31 date: 2024-12-31 date: 2024-03-07 date: 2024-03-12 name: Istituto Auxologico Italiano class: OTHER name: University of Turin, Italy bri... |
i) is observed in obesity ii) it can be modulated in interactive action contexts, as was previously observed in healthy participants. |
Participants will compare the loudness of target sound with a comparison tone, which can be prompt by the participant by pressing a button on their own will (i.e., individual context) or upon the experimenter\'s signal (i.e., interactive context); externally-generated sounds are produced in the opposite way. condit... |
<|newrecord|> nctId: NCT06298526 id: 21C307 briefTitle: Auditory Sensory Attenuation in Anorexia Nervosa acronym: UdSA_AN overallStatus: ACTIVE_NOT_RECRUITING date: 2023-03-01 date: 2024-02-29 date: 2024-12-31 date: 2024-03-07 date: 2024-03-12 name: Istituto Auxologico Italiano class: OTHER briefSummary: The goal of th... |
i) is observed in anorexia nervosa ii) it can be modulated in interactive action contexts, as was previously observed in healthy participants. |
Participants will compare the loudness of target sound with a comparison tone, which can be prompt by the participant by pressing a button on their own will (i.e., individual context) or upon the experimenter\'s signal (i.e., interactive context); externally-generated sounds are produced in the opposite way. condit... |
<|newrecord|> nctId: NCT06298513 id: 09C338 briefTitle: Autonomic and Metabolic Response to Cardiac Rehabilitation After Acute MI acronym: RIABILITOMICA overallStatus: RECRUITING date: 2023-05-02 date: 2025-04 date: 2025-12 date: 2024-03-07 date: 2024-03-07 name: Istituto Auxologico Italiano class: OTHER briefSummary: ... |
<|newrecord|> nctId: NCT06298500 id: AAG-O-H-2115 briefTitle: Clinical Performance of HISTOACRYL® LAPFIX - CANNULA for Laparoscopic Inguinal Hernia Repair acronym: HISTOLAP overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-06 date: 2024-09 date: 2024-03-07 date: 2024-03-08 name: Aesculap AG class: INDUSTRY nam... |
<|newrecord|> nctId: NCT06298487 id: CHRD 1023 briefTitle: Evaluation of the Impact of Therapeutic Education Workshops for COPD Patients in the North-West Val d'Oise Area acronym: MPSAT-ETP overallStatus: RECRUITING date: 2024-03-11 date: 2024-09 date: 2024-09 date: 2024-03-07 date: 2024-04-04 name: Hôpital NOVO class:... |
<|newrecord|> nctId: NCT06298474 id: 2R44AG071105-03 type: NIH link: https://reporter.nih.gov/quickSearch/2R44AG071105-03 briefTitle: The BRAIN App (Phase 2 SBIR) overallStatus: NOT_YET_RECRUITING date: 2025-02-15 date: 2025-11-15 date: 2025-11-30 date: 2024-03-07 date: 2024-03-26 name: Hopeful Aging class: INDUSTRY br... |
The proposed Phase II study will involve the continued development and evaluation of a multi-faceted software platform called "Building Relationships using Artificial Intelligence and Nostalgia" or BRAIN. The BRAIN Platform will be the first-ever Artificial Intelligence (AI) powered CST digital therapy platform for PLW... |
<|newrecord|> nctId: NCT06298461 id: BowelPrep briefTitle: Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease. overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2025-06 date: 2024-03-07 date: 2024-03-07 name: University of Manitoba class: OTHER name: Canadi... |
<|newrecord|> nctId: NCT06298448 id: NL83176.042.23 briefTitle: eGPA and Local Inflammation Within the Ear, Nose and Throat Area overallStatus: RECRUITING date: 2024-02-14 date: 2027-12 date: 2028-12 date: 2024-03-07 date: 2024-03-07 name: University Medical Center Groningen class: OTHER name: GlaxoSmithKline briefSumm... |
<|newrecord|> nctId: NCT06298435 id: 17536 briefTitle: Optimising Ventilatory Strategies by Using Positive Respiratory Integer Measurements acronym: OPTIMVSPRIME overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-04-01 date: 2025-04-01 date: 2024-03-07 date: 2024-03-07 name: University Medical Center Groning... |
Main research question |
* To determine the relationship between the use of mathematically identifiable integer ventilator parameter sets and patient outcomes |
* Design (including population, confounders/outcomes) Retrospective database study of all cases of adult patients undergoing procedures in the UMCG under general anesthesia with IPPV between 01-01-2018 and 01-04-2023. Multivariate and mixed-model analyses, where appropriate, will be corrections for patient specific cha... |
* Expected results Using mathematically identifiable integer ventilatory parameter sets improves respiratory and/or hemodynamic patient outcomes. conditions: Hypoxemia conditions: Hypercapnia conditions: Ventilator Associated Pneumonia conditions: Complication of Anesthesia conditions: Postoperative Complications study... |
<|newrecord|> nctId: NCT06298422 id: 806433 briefTitle: Oxygen Saturations Across Tones of Skin acronym: O2SATS overallStatus: RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-06-30 date: 2024-03-07 date: 2024-03-07 name: University of California, San Diego class: OTHER briefSummary: Pulse oximetry, or SpO2, is ... |
<|newrecord|> nctId: NCT06298409 id: EB04 briefTitle: Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan® overallStatus: RECRUITING date: 2024-02-15 date: 2024-09-15 date: 2024-12-15 date: 2024-03-07 date: 2024-03-07 name: Envivo Bio Inc class: INDUSTRY briefSummary: We will s... |
<|newrecord|> nctId: NCT06298396 id: CLTD5853 briefTitle: Investigating Stimulation Parameter and Electrode Mode Changes on Speech Perception in Experienced Adult Cochlear Implant Recipients acronym: DUAL overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2025-04 date: 2024-03-07 date: 2024-03-07 name:... |
<|newrecord|> nctId: NCT06298383 id: ERU1 briefTitle: The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-07-15 date: 2024-09-15 date: 2024-03-07 date: 2024-03-07 name: Cairo University class: OTHER name: Egyptian Russian U... |
<|newrecord|> nctId: NCT06298370 id: PENG study briefTitle: The Efficacy of Combined Intrathecal Morphine and PENG Block on Postoperative Pain in Hip Arthroplasty acronym: PENG overallStatus: RECRUITING date: 2024-03-18 date: 2024-06-08 date: 2024-07-08 date: 2024-03-07 date: 2024-03-07 name: Bezmialem Vakif University... |
<|newrecord|> nctId: NCT06298357 id: 300012601 id: LAIKPRI02012024 type: OTHER_GRANT domain: Kaul Pediatric Research Institute Pilot Grant briefTitle: Virtual Reality Gaming for Exercise and Mindfulness Among Pediatric Cancer Rehabilitation overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-12-31 date: 2026-... |
<|newrecord|> nctId: NCT06298344 id: 002 briefTitle: The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-12-31 date: 2025-01-01 date: 2024-03-07 date: 2024-03-07 name: Universitas Sumatera Utara clas... |
<|newrecord|> nctId: NCT06298331 id: KA-23073 briefTitle: Investigation of the Additional Effects of Aerobic Exercise Training to Abdominal Massage in Functional Constipation overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2026-03-15 date: 2026-03-15 date: 2024-03-07 date: 2024-03-07 name: Hacettepe University... |
<|newrecord|> nctId: NCT06298318 id: Acute Binge Drink briefTitle: Metabolic Changes in Healthy Subjects With Acute Binge Drink acronym: MeABD overallStatus: ENROLLING_BY_INVITATION date: 2024-04-18 date: 2024-07-19 date: 2026-07-18 date: 2024-03-07 date: 2024-04-17 name: Zhejiang Chinese Medical University class: OTHE... |
1. if acute binge drink could alleviate liver injury and hepatic steatosis. conditions: Binge Drinking conditions: Liver Injury conditions: Hepatic Steatosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: QUADRUPLE whoMasked: PAR... |
<|newrecord|> nctId: NCT06298305 id: QUANTIB briefTitle: Artificial Intelligence & Prostate Cancer acronym: QUANTIB overallStatus: ACTIVE_NOT_RECRUITING date: 2022-09-01 date: 2023-10-10 date: 2024-12 date: 2024-03-07 date: 2024-03-07 name: IRCCS San Raffaele class: OTHER briefSummary: This is a single center, blinded ... |
<|newrecord|> nctId: NCT06298292 id: ZerominisCT01 briefTitle: Acceptability/Tolerance of Protein Substitutes in Tablet Form for the Dietary Management of Rare Aminoacidopathies acronym: ZeroMinisMR overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-03-31 date: 2026-06-30 date: 2024-03-07 date: 2024-03-07 na... |
<|newrecord|> nctId: NCT06298279 id: 2023-436 briefTitle: Assessing Social Learning and Course Delivery Timing in Internet-delivered Cognitive Behaviour Therapy for Public Safety Personnel overallStatus: NOT_YET_RECRUITING date: 2024-03-12 date: 2025-04-30 date: 2025-04-30 date: 2024-03-07 date: 2024-03-07 name: Univer... |
<|newrecord|> nctId: NCT06298266 id: GD2H-XYK-001 briefTitle: To Assess Safety, Tolerability, and Efficacy of Anti-GPRC5D-CD19-CAR-T in Relapsed/Refractory Multiple Myeloma overallStatus: NOT_YET_RECRUITING date: 2024-03-29 date: 2026-05-31 date: 2026-12-31 date: 2024-03-07 date: 2024-03-07 name: Guangdong Second Provi... |
<|newrecord|> nctId: NCT06298253 id: 2024P000832 briefTitle: Behavioral Economics to Implement a Traffic Light Nutrition Ranking System: Study 2 acronym: BeWell overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2027-06 date: 2028-06 date: 2024-03-07 date: 2024-04-09 name: Massachusetts General Hospital class: OTHER... |
<|newrecord|> nctId: NCT06298240 id: 4R22/074 briefTitle: Implementation of Nursing Demand Management as a Factor for Improvement in a Primary Care Emergency Center. overallStatus: ACTIVE_NOT_RECRUITING date: 2022-10-01 date: 2024-01-05 date: 2024-09-01 date: 2024-03-07 date: 2024-04-15 name: Fundacio d'Investigacio en... |
The promotion of the autonomous role of nursing through the implementation of nurse demand management in the urgent spontaneous demand of low complexity can be transcendent, both in the optimisation of health resources in primary care and in the management of the demand for care. |
Hypothesis: The implementation of nurse demand management is a factor of improvement in the efficiency and quality of care in the Primary Care Emergency Centre of the city of Mataró (Barcelona, Spain). Objectives: The main objective of this study was to determine whether the implementation of nurse demand management is... |
<|newrecord|> nctId: NCT06298227 id: Medipol Hospital 1 briefTitle: Erector Spinae Plane Block vs Quadratus Lumborum Block for Laparoscopic Nephrectomy overallStatus: RECRUITING date: 2024-03-11 date: 2024-07-20 date: 2024-07-30 date: 2024-03-07 date: 2024-03-15 name: Istanbul Medipol University Hospital class: OTHER b... |
US-guided erector spinae plane block (ESPB) is performed at the level of the T11 transverse process. After visualization of the erector spinae (ES) muscle and the transverse process, local anesthetic is injected under the ES muscle. ESPB provides a sensory block of the anterior, posterior, and lateral thoracic and abdo... |
This study aims to compare the effectiveness of US-guided ESPB and QLB on postoperative pain control after laparoscopic nephrectomy. conditions: Kidney Diseases conditions: Kidney Failure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Sixty patients... |
<|newrecord|> nctId: NCT06298214 id: RP-23-019 briefTitle: Testing the Effectiveness of the Her Health Program to Add Healthcare Value in the Fourth Trimester acronym: Her Health overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-01-01 date: 2026-06-01 date: 2024-03-07 date: 2024-03-07 name: Elizabeth F Sutt... |
The main question\[s\] the study aims to answer are: |
* Can the Her Health program increase access to healthcare in the first year postpartum? |
* Can the Her Health program increase knowledge about healthcare and change feelings toward the healthcare system? |
Participants will complete one research visit in which they will be enrolled and told which group they will be in- "Her Health Program" group or "Usual Care" group. If they are placed in the "Her Health Program" group, they will receive their usual care + the addition of an extra healthcare team member(called a communi... |
Researchers will compare those who receive the Her Health Program and those who do not receive the program to see if the Her Health Program can help women get healthcare in the first year after having a baby. conditions: Postpartum conditions: Pregnancy Related studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZE... |
<|newrecord|> nctId: NCT06298201 id: IMAGINE2024 briefTitle: E-Based Physical Exercise in Patients With Multiple Sclerosis and Comorbidity acronym: COMPACT overallStatus: RECRUITING date: 2024-04 date: 2024-11 date: 2025-07 date: 2024-03-07 date: 2024-03-07 name: University of Southern Denmark class: OTHER briefSummary... |
Aims: To assess the effect of e-based PE in addition to usual care in pwMS on clinical outcome and the levels of inflammatory, metabolic, and neurodegenerative mediators. Furthermore, to determine whether PE plays a role in the modification of comorbidities with a focus on vascular comorbidity and related risk factors,... |
Method: This study will be prospective with longitudinal follow-up of pwMS with and without comorbidities. The physical activity of pwMS will be measured at baseline and after six months by accelerometers. In a randomized controlled trial (RCT) patients will be randomly assigned in a 1:1 ratio to receive either usual c... |
Conclusion: This study will contribute to the rehabilitation and improved quality of life of pwMS particularly of patients with comorbidities. The potential for e-based PE at home to encourage sustained exercise engagement among pwMS will be evaluated, offering a significant contribution to the field of digital healthc... |
<|newrecord|> nctId: NCT06298188 id: RisaKids briefTitle: Risankizumab in Children With Crohn's Disease (RisaKids) overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-10 date: 2026-10 date: 2024-03-07 date: 2024-03-07 name: Shaare Zedek Medical Center class: OTHER briefSummary: The goal of this observational stu... |
This is a 1-year prospective multi-center cohort study of children commencing on risankizumab for pediatric CD with 2 years extension for long-term follow-up. The investigators will record clinical manifestations, blood markers and fecal calprotectin, with monitoring for safety signals including infusion and injection ... |
<|newrecord|> nctId: NCT06298175 id: 2021-157 briefTitle: Self-Management Training With Online Intervention Process for Young Adults With Chronic Conditions overallStatus: COMPLETED date: 2021-04-15 date: 2021-04-15 date: 2021-08-15 date: 2024-03-07 date: 2024-03-07 name: Saglik Bilimleri Universitesi class: OTHER brie... |
<|newrecord|> nctId: NCT06298162 id: 2018-1279 briefTitle: Assessment of Pouch Emptying With MRI After Roux-en-Y Gastric Bypass acronym: MRI pouch overallStatus: COMPLETED date: 2019-07-25 date: 2020-02-01 date: 2020-02-01 date: 2024-03-07 date: 2024-03-07 name: Rijnstate Hospital class: OTHER briefSummary: A cross-sec... |
<|newrecord|> nctId: NCT06298149 id: 2023-650-EXEMPT id: 1U54CA280812-01 type: NIH link: https://reporter.nih.gov/quickSearch/1U54CA280812-01 briefTitle: Reach Through Equitable Implementation of Turtle Island Tales overallStatus: ENROLLING_BY_INVITATION date: 2023-11-01 date: 2028-04-30 date: 2028-04-30 date: 2024-03-... |
<|newrecord|> nctId: NCT06298136 id: 15610923 briefTitle: The Effects of an Online Mindfulness-based Intervention for Children With Attention-Deficit/Hyperactivity Disorder acronym: MindADHD overallStatus: RECRUITING date: 2024-02-01 date: 2026-12-31 date: 2026-12-31 date: 2024-03-07 date: 2024-03-07 name: The Hong Kon... |
<|newrecord|> nctId: NCT06298123 id: adjuvant-03 briefTitle: Postoperative Adjuvant Immunotherapy for Hepatocellular Carcinoma: Risk Factor Analysis and Prognostic Modelling overallStatus: COMPLETED date: 2019-02-01 date: 2023-02-01 date: 2023-02-01 date: 2024-03-07 date: 2024-03-07 name: Chen Xiaoping class: OTHER bri... |
<|newrecord|> nctId: NCT06298110 id: PRP in Abdominal hysterectomy briefTitle: The Effect of PRP on Wound Healing in High Risk Patients Undergoing Abdominal Hysterectomy overallStatus: NOT_YET_RECRUITING date: 2024-03-10 date: 2024-08-25 date: 2024-09-25 date: 2024-03-07 date: 2024-03-08 name: Helwan University class: ... |
<|newrecord|> nctId: NCT06298097 id: 2019.11 briefTitle: Brain Connectivity Measured With High-density Electroencephalography acronym: NEUROCONN overallStatus: RECRUITING date: 2020-06-11 date: 2025-02-02 date: 2025-02-02 date: 2024-03-07 date: 2024-03-07 name: IRCCS San Camillo, Venezia, Italy class: OTHER briefSummar... |
<|newrecord|> nctId: NCT06298084 id: 2023-505925-15-00 id: 2023/3668 type: OTHER domain: CSET number briefTitle: Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression ... |
The first 2 modules will evaluate: i. safety and efficacy of HER3-DXd with olaparib in patients with HER2-low and HER2-positive ABC progressed on T-DXd (Module 1) and HER3-DXd monotherapy in patients with HER2-low ABC progressed on T-DXd (Module 0). |
The main objective of Part 1 is to assess the safety and tolerability of HER3-DXd monotherapy and combination and to determine the recommended phase 2 dose (RP2D) of the combination containing HER3-DXd. |
The main objective of Part 2 is to assess the efficacy of study therapies in each module based on investigator assessment as evaluated by the objective response rate (ORR) at 6 months. conditions: Breast Cancer Metastatic conditions: HER2-positive Metastatic Breast Cancer conditions: HER2 Low Breast Carcinoma condition... |
<|newrecord|> nctId: NCT06298071 id: SIBP-R002-Ib briefTitle: A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout. overallStatus: RECRUITING date: 2023-03-03 date: 2024-12-30 date: 2025-12-30 date: 2024-03-07 date: 2024-03-07 name: Shanghai Institute Of Biological ... |
<|newrecord|> nctId: NCT06298058 id: SIBP-A13-I briefTitle: A Clinical Trial of SIBP-A13 Injection in the Treatment of Advanced Malignant Solid Tumor Patients. overallStatus: NOT_YET_RECRUITING date: 2024-03-12 date: 2026-04-30 date: 2026-06-30 date: 2024-03-07 date: 2024-03-07 name: Shanghai Institute Of Biological Pr... |
<|newrecord|> nctId: NCT06298045 id: DIM-06790-002 briefTitle: Effectiveness of a Combination of Trimetazidine With One Hemodynamic Agent in Patients Recently Diagnosed With Stable Angina and Still Symptomatic Despite First Line Hemodynamic Therapy overallStatus: RECRUITING date: 2023-07-15 date: 2025-03-31 date: 2025-... |
<|newrecord|> nctId: NCT06298032 id: 000414 briefTitle: A Study Investigating the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Olamkicept in Healthy Persons overallStatus: RECRUITING date: 2024-02-20 date: 2024-11-12 date: 2024-11-12 date: 2024-03-07 date: 2024-03-07 name: Ferring Pharmaceuticals class:... |
<|newrecord|> nctId: NCT06298019 id: 73464 briefTitle: Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-04 date: 2039-04 date: 2024-03-07 date: 2024-03-07 name: Stanford University class: OTHER briefSummary: The goal of this clinical trial is t... |
The main questions the study intends to answer are: |
* Understanding how well patients tolerate undergoing this therapy in terms of side effects; |
* Getting an early idea if this therapy can help certain aspects of the autoimmune disease, including inflammation in the skin, muscles, and lungs; conditions: Dermatomyositis studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SEQUENTIAL interventionModelDescription: Patients will be enrolled in... |
<|newrecord|> nctId: NCT06298006 id: 275025 briefTitle: A Two Year Longitudinal Clinical Study of Neurocognitive and Psychiatric Symptoms in Post COVID-19 Patients acronym: PASC24 overallStatus: RECRUITING date: 2022-02-22 date: 2026-12-31 date: 2027-06-30 date: 2024-03-07 date: 2024-03-07 name: Region Örebro County cl... |
<|newrecord|> nctId: NCT06297993 id: WIND-PSC-01 briefTitle: Adult Patients With Primary Sclerosing Cholangitis acronym: WIND-PSC overallStatus: RECRUITING date: 2024-04 date: 2029-01 date: 2031-01 date: 2024-03-07 date: 2024-04-09 name: Arbor Research Collaborative for Health class: OTHER briefSummary: Develop an appr... |
<|newrecord|> nctId: NCT06297980 id: 23-1513 briefTitle: Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes acronym: MERIT overallStatus: RECRUITING date: 2024-03-15 date: 2026-10-31 date: 2026-10-31 date: 2024-03-07 date: 2024-03-07 name: University of Colorado, Denver class: OTHE... |
<|newrecord|> nctId: NCT06297967 id: CSAPG-33 briefTitle: Acetic Acid 2% Solution for Skin Ulcers acronym: ECA-AA overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-04 date: 2026-06 date: 2024-03-07 date: 2024-03-12 name: Consorci Sanitari de l'Alt Penedès i Garraf class: OTHER briefSummary: The objective of th... |
Participants will be randomly assigned to receive either the acetic acid solution treatment or the standard current treatment. conditions: Ulcer, Skin studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count:... |
<|newrecord|> nctId: NCT06297954 id: GA22-00011 briefTitle: Usefulness of Metoclopramide to Improve Endoscopic Visualization in Upper Gastrointestinal Bleeding overallStatus: RECRUITING date: 2023-03-16 date: 2024-06 date: 2024-06 date: 2024-03-07 date: 2024-03-07 name: Universidad Autonoma de Nuevo Leon class: OTHER b... |
<|newrecord|> nctId: NCT06297941 id: REM-422-102 briefTitle: Study of REM-422 in Patients With AML or Higher Risk MDS overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2026-03-15 date: 2027-06-15 date: 2024-03-07 date: 2024-04-23 name: Remix Therapeutics class: INDUSTRY briefSummary: The goal of this study is to... |
<|newrecord|> nctId: NCT06297928 id: 2023/11238/I briefTitle: Metabolomics and Bariatric Surgery in Patients With Metabolically Unhealthy Obesity overallStatus: RECRUITING date: 2024-01-01 date: 2025-06-01 date: 2026-12-31 date: 2024-03-07 date: 2024-03-07 name: Parc de Salut Mar class: OTHER briefSummary: The goal of ... |
* Can metabolic markers predict the transition from metabolically unhealthy obesity to metabolically healthy obesity after bariatric surgery? |
* How do metabolic profiles change in individuals with metabolically healthy obesity after bariatric surgery? |
* What are the metabolic differences between individuals with metabolically healthy and unhealthy obesity before and after bariatric surgery? |
Participants will undergo routine evaluations and blood tests before and after bariatric surgery. These tests will include assessments of metabolic health markers and sampling of blood plasma for metabolomic analysis. The study will study changes in metabolic profiles between individuals who transition to metabolically... |
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