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<|newrecord|> nctId: NCT06292598 id: AOI2022/2023/CDR-01 briefTitle: Bacterial Translocation and Gut Microbiota in Type 1 Narcolepsy Patients Versus a Control Population acronym: NARCOBIOTE overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-05 date: 2027-05 date: 2024-03-05 date: 2024-03-05 name: Centre Hospitalier Universitaire de Nīmes class: OTHER briefSummary: Narcolepsy type 1 (NT1) is a rare disease characterized by severe drowsiness, cataplexy, hypnagogic hallucinations, sleep paralysis, poor night sleep, and often obesity. NT1 is caused by irreversible loss of orexin (ORX)/hypocretin neurons in the lateral hypothalamus with decreased ORX levels in the cerebrospinal fluid (CSF). Although the underlying process leading to this destruction remains unclear; an autoimmune origin is suspected.
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The study authors recently compared the bacterial communities of the fecal microbiota of NT1 patients and control subjects. Initial results demonstrated a difference in overall bacterial community structure in NT1 compared to controls, as assessed by beta diversity, even after adjusting for body mass index (BMI). The Shannon biodiversity index was also correlated with the duration of NT1 disease. However, no association was found between the structure of the microbial community and the clinical characteristics of NT1 patients.
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In 2022, a second study from the SOMNOBANK cohort on a larger population confirmed these results, showing dysbiosis between NT1 patients and the control population. The altered intestinal microbial diversity supports the important role of the environment in the development and pathogenesis of NT1. Other studies have established a link between dysbiosis, intestinal permeability and inflammation in other neuroimmune pathologies. Currently, no study has focused on these phenomena of bacterial translocation, intestinal permeability and immune activation linked to the microbiota in type 1 narcolepsy patients.
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The study hypothesis is that NT1 patients with dysbiosis in their intestinal microbiota also present a bacterial translocation with an intestinal origin, leading to a systemic inflammatory syndrome favoring an autoimmune damage destroying hypocretin neurons in the hypothalamus. The study authors suspect that microbial elements (DNA) involved in the autoimmune process could be detected in the CSF. This bacterial translocation could vary over time depending on: i) the progression of the disease and its management; ii) changing dysbiosis and: iii) the increase in intestinal permeability and inflammation. conditions: Narcolepsy Type 1 conditions: Bacterial Translocation studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 120 type: ESTIMATED name: Blood sample name: Stool sample name: CSF sample measure: Plasma bacterial translocation profiles between groups measure: Plasma bacterial translocation profiles in NT1 patients measure: Taxonomic characteristics of DNA in the CSF of NT1 patients according to narcolepsy severity measure: Taxonomic characteristics of plasma bacterial DNA in patients with high bacterial translocation measure: Taxonomic characteristics of plasma bacterial DNA in patients with high bacterial translocation measure: Beta diversity of the intestinal microbiota between groups measure: Beta diversity of the intestinal microbiota in NT1 patients measure: Alpha diversity of the intestinal microbiota between groups measure: Alpha diversity of the intestinal microbiota in NT1 patients measure: Composition of the intestinal microbiota between groups measure: Composition of the intestinal microbiota between groups measure: Plasma Intestinal Fatty Acid Binding Protein (i-FABP) profile between groups measure: Plasma Intestinal Fatty Acid Binding Protein (i-FABP) profile in NT1 patients measure: Plasma LPS-binding Protein (LBP) profile between groups measure: Plasma LPS-binding Protein (LBP) profile in NT1 patients measure: Plasma Soluble CD14 profile between groups measure: Plasma Soluble CD14 profile in NT1 patients measure: Age of onset of symptoms in NT1 patients measure: Duration of disease progression in NT1 patients measure: Severity of sleep-related symptoms in NT1 patients measure: Severity of narcolepsy symptoms in NT1 patients measure: Description of comorbidities in NT1 patients measure: Sleep onset latency in NT1 patients measure: Number of rapid eye movement sleep episodes in NT1 patients measure: Orexin levels in CSF in NT1 patients sex: ALL minimumAge: 10 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Nîmes University Hospital city: Nîmes state: Gard zip: 30029 country: France name: Anissa MEGZARI role: CONTACT phone: +33 4 66 68 42 36 email: drc@chu-nimes.fr name: Catherine DUNYACH-REMY role: PRINCIPAL_INVESTIGATOR name: Jean-Philippe LAVIGNE role: SUB_INVESTIGATOR name: Béatrix ABRIL role: SUB_INVESTIGATOR lat: 43.83333 lon: 4.35 facility: Centre Hospitalier Universitaire de Montpellier city: Montpellier country: France name: Yves DAUVILLIERS role: CONTACT email: y-dauvilliers@chu-montpellier.fr name: Yves DAUVILLIERS role: PRINCIPAL_INVESTIGATOR name: Lucie BARATEAU role: SUB_INVESTIGATOR lat: 43.61092 lon: 3.87723 hasResults: False
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<|newrecord|> nctId: NCT06292585 id: AEDH-MT briefTitle: Acute EpiDural Hematoma Treated With Middle Meningeal Artery Embolization: a Randomized Trial (AEDH-MT) overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-08 date: 2026-12 date: 2024-03-05 date: 2024-03-05 name: Changhai Hospital class: OTHER briefSummary: A prospective, multicenter, randomized controlled, open-label, blinded endpoint evaluation study. conditions: EpiDural Hematoma conditions: Traumatic Brain Injury studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 168 type: ESTIMATED name: MMA embolization plus medical therapy name: Medical therapy alone measure: The proportion of patients who die within 72 hours after injury or progress to require craniotomy due to epidural hematoma. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Changhai hospital city: Shanghai state: Shanghai zip: 200433 country: China lat: 31.22222 lon: 121.45806 hasResults: False
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<|newrecord|> nctId: NCT06292572 id: 2024PI029 briefTitle: Clinical Characteristics and Surgical Outcomes of the Fellow Eye in Bilateral Retinal Detachments overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-11-01 date: 2024-11-01 date: 2024-03-05 date: 2024-03-05 name: Central Hospital, Nancy, France class: OTHER briefSummary: To assess the clinical features and the surgical outcomes of RD repair surgery of the fellow eye in bilateral retinal detachments conditions: Retinal Detachment studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 25 type: ESTIMATED name: Retinal Detachment Surgery measure: Rate of surgical success measure: Visual Acuity sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CHRU de Nancy city: Vandoeuvre les nancy state: Meurthe-et-Moselle zip: 54511 country: France lat: 48.65 lon: 6.18333 hasResults: False
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<|newrecord|> nctId: NCT06292559 id: STN or GPi in Meige Syndrom briefTitle: A Comparison Between STN-DBS and GPi-DBS in Meige Syndrome Evaluated by Flexible Electrodes overallStatus: RECRUITING date: 2023-11-30 date: 2024-11-30 date: 2025-11-30 date: 2024-03-05 date: 2024-03-05 name: Qilu Hospital of Shandong University class: OTHER briefSummary: Deep-brain stimulation (DBS) is an effective treatment for patients with Meige syndrome. The globus pallidus interna (GPi) and the subthalamic nucleus (STN) are both accepted targets for this treatment. Researchers designed this study to compare the 12-month outcomes for patients who undergo bilateral stimulation of the GPi or STN. conditions: Meige Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: Bilateral STN deep brain stimulation name: Bilateral GPi deep brain stimulation measure: Change in motor function measure: health-related quality of life measure: sleep quality status measure: Mental syndrome measure: Mental syndrome sex: ALL minimumAge: 30 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chao Zhang status: RECRUITING city: Jinan state: Sichuan zip: 250100 country: China name: chao zhang role: CONTACT phone: +8613969007232 email: chao_zhang@sdu.edu.cn lat: 36.66833 lon: 116.99722 hasResults: False
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<|newrecord|> nctId: NCT06292546 id: ZYC-Hp2024 briefTitle: Effect of Intestinal Microecology After HDDT Combined With Probiotics for Helicobacter Pylori Eradication overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-09-01 date: 2024-09-01 date: 2024-03-05 date: 2024-03-07 name: Zhongshan Hospital (Xiamen), Fudan University class: OTHER briefSummary: The aim of this study was to evaluate the effect of Intestinal microecology after high dose dual therapy combined with probiotics for Helicobacter pylori eradication conditions: H Pylori Infection Eradication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 80 type: ESTIMATED name: Vonorason name: Amoxicillin name: Bacillus subtilis enteric-coated capsules measure: Gut Microbiota measure: Fecal metabolites measure: Eradication rate measure: Frequency of the adverse events measure: Compliance rate of the drugs sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
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<|newrecord|> nctId: NCT06292533 id: UTAR-30-2024 briefTitle: Effectiveness of Ultrapulse for the Treatment of Androgenic Alopecia Among Malaysian: A Quasi-experimental Study overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-10 date: 2024-10 date: 2024-03-05 date: 2024-03-05 name: Universiti Tunku Abdul Rahman class: OTHER briefSummary: The goal of this study is to to evaluate the effectiveness of Ultrapulse for the treatment of androgenic alopecia among Malaysian. The main questions it aims to answer are:
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* the efficacy of Ultrapulse in treatment of androgenic alopecia among Malaysian
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* the safety and adverse effect of Ultrapulse treatment.
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* the quality of life of androgenic alopecia among Malaysian. conditions: Androgenic Alopecia conditions: Alopecia studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 92 type: ESTIMATED name: Er:YAG laser measure: Global assessment of hair growth measure: Patient satisfaction measure: Quality of Life of Patient measure: Adverse effects sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
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<|newrecord|> nctId: NCT06292520 id: 4847 briefTitle: Comparison of ABLLS-R and Portage Guide in the Development of Receptive Language Skills Autism Spectrum Disorder. overallStatus: COMPLETED date: 2023-06-10 date: 2023-08-20 date: 2023-12-10 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: Language is the system someone uses to communicate with another person. This covers the origins and construction of words, their definitions, and the use of language in various contexts. In normally developing children, receptive language skills are typically much more advanced than expressive language skills. However, some studies found that toddlers and kids with ASD had a relatively greater impairment in receptive language skills than in expressive language skills. The study will evaluate the ABLLS-R (Assessment of Basic Language and Learning Skills test) and Portage guidance and compare their effectiveness in developing the Receptive Language Skills in children with Autism Spectrum Disorder (N=12).
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The study will follow the Randomized control trial study design and a purposive sampling technique will be used. Data will be collected from a special education centre BASES (Behaviour and special education services), Lahore. Children with autism spectrum disorder with mild to moderate severity level will be included in the study. The age range of the children will be from three years to seven years. Children with other neurological disorders or any comorbid conditions will be excluded from the study. The consent form will be filled out by parents of children who meet the inclusion criteria. The autism screening tool will apply by the speech and language pathologist. Half of the total number of children will receive therapeutic intervention under ABLLS-R protocol and other will receive Interventions under portage guide protocol. The data will be analysed by using SPSS 22 statistical software. The results of the study of both the groups will be compared and conclusion will be made on the basis of results. Receptive language skills are crucial for communication and social interaction. Research comparing these assessment tools can contribute to the development of more effective early intervention programs for children with ASD. By identifying the most appropriate assessment tool and intervention strategies, these programs can be better designed to support early language development and promote better long-term outcomes. By understanding the strengths and limitations of each assessment tool, professionals can create more individualized treatment plans for children with ASD conditions: Autism Spectrum Disorders conditions: Non-verbal Learning Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: SINGLE whoMasked: PARTICIPANT count: 12 type: ACTUAL name: Portage Guide Protocol name: ABLLS-R protocol measure: ABLLS-R for the development of receptive language in children with Autism measure: Portage Guide for the development of receptive language in children with Autism sex: ALL minimumAge: 3 Years maximumAge: 7 Years stdAges: CHILD facility: Bases Institute city: Lahore state: Punjab zip: 05309 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
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<|newrecord|> nctId: NCT06292507 id: REC/RCR&AHS/23/0734 briefTitle: Comparative Effects of Myofascial Stretch and Contract-relax in Children With Spastic cp overallStatus: RECRUITING date: 2023-12-01 date: 2024-03-16 date: 2024-03-25 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: Cerebral palsy (CP) is primarily a neuromotor disorder that affects the development of movement, muscle tone and posture.It is one of the three most common lifelong developmental disabilities, the other two being autism and mental retardation causing considerable hardship to affected individuals and their families. CP is a common problem, the worldwide incidence being 2 to 2.5 per 1000 live births. Myofascial therapy is definable by "the facilitation of mechanical, neural and psycho physiological adaptive potential as interfaced by the myofascial system". The PNF contract-relax technique consists of stretching the target muscle, keeping it in position while the patient isometrically contracts it and relaxes in sequence, producing effects such as maintenance and gain in joint mobility, increased muscle strength, and better motor control whereas The modified Ashworth scale is the most universally accepted clinical tool used to measure the increase of muscle tone This study will be randomized clinical trial and will be conducted in Rasool medical centre Gujrat and City hospital Gujrat. This study will be completed within duration of 6 months after the approval of synopsis.Convenience sampling technique will be used to collect the data. A sample size of total 20 patientswill be taken in the study. 20participants will be equally divided into two group's myofascial stretch and contract-relax stretching techniques having 10participants in each group. Informed consent will be sought from them and they will be clearly explained about the purpose of study.Myofascial Stretching will be applied to Group A and Contract-Relax stretching will be applied to Group B.
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Results will be analyzed on SPSS. conditions: Cerebral Palsy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 22 type: ESTIMATED name: MYOFASCIAL STRETCH name: CONTRACT-RELAX TECHNIQUE measure: Manual Ability Classification system sex: ALL minimumAge: 6 Years maximumAge: 12 Years stdAges: CHILD facility: Mirza Muhammad Farooq status: RECRUITING city: Gujrāt state: Punjab zip: 50700 country: Pakistan name: imran Amjad, PhD role: CONTACT phone: 033224390125 email: imran.amjad@ripha.edu.pk name: Muhammad asif Javed, MS role: CONTACT phone: 03224209422 email: a.javed@ripha.edu.pk lat: 32.5742 lon: 74.07542 hasResults: False
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<|newrecord|> nctId: NCT06292494 id: 1129052082 briefTitle: Focused Ultrasound for Drug-resistant Epilepsy overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2027-12-31 date: 2024-03-05 date: 2024-03-05 name: Taipei Veterans General Hospital, Taiwan class: OTHER_GOV name: InSightec briefSummary: Focused ultrasound (FUS) has been shown to differentially lesion or modulate (excite and inhibit) brain circuit and neural activity across a broad range of acoustic stimulus parameters (intensity, duty cycle, pulse repetition frequency and pulse duration) for decades. From our previous study, FUS sonication may suppress the number of epileptic signal bursts observed in EEG recordings after the induction of acute epilepsy. The presence of the suppressive effect was found in terms of the number of epileptic EEG spikes from the analysis of the unfiltered and theta-band EEG activity, and further discontinue the seizure attacks. EEG activity has also been consistently reported to have a positive correlation with the level of epilepsy, and FUS-mediated reduction of epileptic EEG activity was most notably observed, no matter lesioning or modulating effects. The aims of this study are to demonstrate the safety and efficacy of FUS technology in epilepsy patients and to estimate the optimal parameters of focused ultrasound exposure that will be used in the case of epilepsy. conditions: Focused Ultrasound conditions: MR-guided FUS conditions: Drug Refractory Epilepsy conditions: Drug Resistant Epilepsy conditions: Medication Resistant Epilepsy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Exablate 4000 Transcranial MRgfUS System measure: pulse rate [Safety] measure: blood oxygen saturation level [Safety] measure: MRI [Safety] measure: Incidence of Treatment-Emergent Adverse Events [Tolerability] measure: seizure frequency [efficacy] measure: scalp EEG [efficacy] measure: No. of seizure-free days [efficacy] sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Taipei Veterans General Hospital status: RECRUITING city: Taipei country: Taiwan name: Cheng-Chia Lee, MD. PhD. role: CONTACT email: cclee12@vghtpe.gov.tw lat: 25.04776 lon: 121.53185 hasResults: False
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<|newrecord|> nctId: NCT06292481 id: REC/RCR&AHS/23/0240 briefTitle: Combine Effects of Brunnstorm Movement Therapy and LLLT in Chronic Stroke Patient overallStatus: COMPLETED date: 2023-08-01 date: 2023-09-30 date: 2023-10-10 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: The primary objective of this study is to determine the combined effects of Brunnstorm movement therapy and low level laser therapy on upper limb function in chronic stroke patient. conditions: Chronic Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 48 type: ACTUAL name: Brunnstorm movement therapy name: Combined Brunnstorm Movement therapy and low level laser therapy measure: Fugle meyer Assessment test measure: Box and block test measure: Nine peg hole test measure: to check Muscle tone measure: to measure grip Strength sex: ALL minimumAge: 40 Years maximumAge: 60 Years stdAges: ADULT facility: Govt. Mian Munshi DHQ Teaching hospital city: Lahore state: Punjab zip: 54000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
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<|newrecord|> nctId: NCT06292468 id: REC/RCR&AHS/23/0238 briefTitle: Plantar Cutaneous Sensory Stimulation in Patients With Diabetic Neuropathy overallStatus: COMPLETED date: 2023-07-07 date: 2023-08-18 date: 2023-09-18 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: To determine the effects of plantar cutaneous sensory stimulation on foot tactile sensitivity, postural control, and spatiotemporal gait parameters in patients with diabetic neuropathy. conditions: Diabetic Neuropathies studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 50 type: ACTUAL name: Traditional physical therapy name: Plantar cutaneous sensory stimulation measure: Foot tactile sensitivity measure: Postural control measure: Spatiotemporal gait parameters sex: ALL minimumAge: 45 Years maximumAge: 67 Years stdAges: ADULT stdAges: OLDER_ADULT facility: PhysioFit city: Faisalabad state: Punjab zip: 38000 country: Pakistan lat: 31.41554 lon: 73.08969 facility: Allied Hospital Faisalabad. city: Faisalābad state: Punjab zip: 38000 country: Pakistan lat: 31.41554 lon: 73.08969 hasResults: False
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<|newrecord|> nctId: NCT06292455 id: RIPHAH/RCRS/REC/00713 briefTitle: Association of Anthropometrics With Grip Strength and Smash Quality Post Six Week Elastic Resistance Training overallStatus: COMPLETED date: 2020-07-10 date: 2020-11-30 date: 2020-12-15 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: To determine the association of hand and forearm anthropometrics on grip strength and forehand smash quality of badminton players after six-weeks of elastic resistance training. conditions: Anthropometric Measurements and Elastic Resistance Training conditions: Sports Physical Therapy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: NONE count: 20 type: ACTUAL name: Elastic resistance training name: Conventional Resistance Training measure: Smash quality (Power) measure: Smash quality (Speed) measure: Smash quality (Distance) sex: ALL minimumAge: 16 Years maximumAge: 25 Years stdAges: CHILD stdAges: ADULT facility: Riphah international University city: Islamabad state: ICT zip: 44000 country: Pakistan lat: 33.72148 lon: 73.04329 hasResults: False
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<|newrecord|> nctId: NCT06292442 id: REC/RCR&AHS/23/0237 briefTitle: Effects of HIIT on Muscle Strength, Atrophy and Aerobic Capacity in Stroke Patients. overallStatus: COMPLETED date: 2023-09-01 date: 2023-10-01 date: 2023-11-01 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: To determine the effects of High-Intensity Interval Training on muscle strength, atrophy, and aerobic capacity in stroke patients. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 34 type: ACTUAL name: traditional physical therapy name: High intensity interval training measure: Muscle strength measure: Muscle Atrophy measure: 6-Minute Walk Test (6MWT) measure: Aerobic Capacity measure: Fastest Gait Speed sex: ALL minimumAge: 40 Years maximumAge: 60 Years stdAges: ADULT facility: Jinnah Hospital, Lahore city: Lahore state: Punjab zip: 54000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
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<|newrecord|> nctId: NCT06292429 id: REC/RCR & AHS/23/1104 briefTitle: Effects of Complex Training in Cricket Fast Bowlers overallStatus: RECRUITING date: 2023-06-16 date: 2024-06 date: 2024-06 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: This study will be a randomized controlled trial and the data will be collected from National Cricket Academy and domestic cricket clubs. The sample size will be calculated by conducting a pilot study. There will be three groups. Group-A will be receiving Complex training, Group-B will be receiving Conventional training and Group C as a Control Group. Athletes with same physical fitness level will be recruited. There will be parallel assignment of the participants. Assessor will be kept blinded. All the parameters would be assessed at Baseline, 6 Weeks, 12 Weeks. Physical fitness will be assessed through Field Testing. Bowling performance will be assessed through speed machine and Kinovea Software. Work capacity will be assessed through step testing. Muscle strength will be assessed through Dynamometer. Lastly, BMD will be assessed though Bone Densitometer. conditions: Resistance Training conditions: Plyometric Exercise conditions: Sports Physical Therapy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomized controlled trial primaryPurpose: OTHER masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Complex Training name: Conventional Training name: Control Group measure: Physical fitness (linear speed capability) measure: Physical fitness (lower limb explosive power) measure: Physical fitness (upper body strength test) measure: Physical fitness (lower body strength test) measure: Physical fitness (upper body muscular endurance) measure: Physical fitness (aerobic capacity) measure: Bowling performance (Ball speed) measure: Bowling performance (run-up time) measure: Bowling performance (accuracy) measure: Bowling performance (RPE) measure: Work capacity measure: Muscle Strength measure: Bone Density sex: MALE minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT facility: Pakistan Sports Board Coaching Center status: RECRUITING city: Lahore state: Punjab zip: 54000 country: Pakistan name: Nasrullah Rana role: CONTACT phone: +92 334 5492964 name: Muhammad Atif Javed, PP-DPT role: PRINCIPAL_INVESTIGATOR name: Syed Asadullah Arslan, Ph.D. role: SUB_INVESTIGATOR lat: 31.558 lon: 74.35071 hasResults: False
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<|newrecord|> nctId: NCT06292416 id: REC/0257Huma Saleem briefTitle: Mirror Therapy With Sensory Motor Training in Children With CP overallStatus: RECRUITING date: 2023-12-30 date: 2024-05-14 date: 2024-05-14 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: The study compares two interventions in CP children: mirror therapy with sensory motor training versus mirror therapy with motor training. Mirror therapy works by manipulating the brain out of pain, ultimately improving movement in patients with one-sided paralysis. It can be used in combination with other therapies to assist patients with cerebral palsy in retraining the brains, restoring function, and enhancing the overall quality of life. The purpose of this study is to use a combination of Mirror therapy with sensory motor training and motor training and observe which one of these combinations has the most desirable effects in improving movement and quality of life in CP Children conditions: Cerebral Palsy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Assignment primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: participants and outcome assessors will be kept blind about the intervention which the patients will be receiving. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 54 type: ESTIMATED name: Experimental: Mirror therapy with sensory motor training. name: Experimental: Mirror Therapy with motor training name: Experimental: Motor Training measure: The Melbourne Assessment of Unilateral Upper Limb Function (Melbourne Assessment) measure: Jebsen Taylor Hand dysfunction test sex: ALL minimumAge: 6 Years maximumAge: 12 Years stdAges: CHILD facility: Eliya care Centre Faisalabad status: RECRUITING city: Lahore state: Punjab country: Pakistan name: Ammara Abbas, tDPT role: CONTACT phone: 03214932464 email: ammara.musvi@gmail.com name: Huma Saleem, MS NMPT* role: PRINCIPAL_INVESTIGATOR lat: 31.558 lon: 74.35071 hasResults: False
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<|newrecord|> nctId: NCT06292403 id: Farwa Akhtar briefTitle: Effects of Strength Training of Non-paretic Upper and Lower Limb With or Without Mirror Therapy overallStatus: NOT_YET_RECRUITING date: 2024-03-10 date: 2024-12-30 date: 2025-01-01 date: 2024-03-05 date: 2024-03-05 name: Riphah International University class: OTHER briefSummary: The aim of this study is to find the effects of strength training with or without mirror therapy of non-paralytic upper limb for functional activities and in lower limb for gait pattern, balance and stability, and ADLs of paralytic side in patients with acute and sub-acute stroke. A randomized controlled trial that will include total 44 participants .The control group will undergo usual rehabilitation training along with strength training. The trial group will undergo strength training and mirror therapy of NHS on the basis of usual rehabilitation training. For the control group, training time will be 30 minutes, once a day, 3 days a week for 8 weeks. IN trial group, training time will be 30 minutes therapy, once a day, 3 days a week for 8 weeks. were allowed to rest for 3-5 min during each training. Data collected will be analyzed through SPSS 25. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 2 groups
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1. Strength training only group
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2. strength training and mirror therapy group primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 44 type: ESTIMATED name: Strength Training name: Mirror therapy measure: Modified Barthel Index measure: Dynamic Gait Index measure: Berg Balance Scale sex: FEMALE minimumAge: 18 Years maximumAge: 24 Years stdAges: ADULT facility: Fatima Hospital city: Rawalpindi state: Punjab country: Pakistan name: Sara Aabroo, NMPT role: CONTACT phone: 03155185508 email: sara.aabroo@riphah.edu.pk name: Farwa Akhtar, NMPT role: CONTACT lat: 33.6007 lon: 73.0679 hasResults: False
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<|newrecord|> nctId: NCT06292390 id: AIBU-SBF-CY-09 briefTitle: The Effect Of Pet Therapy Applıed To Elders's Sleep And Qualıty Of Lıfe overallStatus: COMPLETED date: 2021-11-15 date: 2022-05-12 date: 2023-06-22 date: 2024-03-05 date: 2024-03-15 name: Tokat Gaziosmanpasa University class: OTHER briefSummary: Quality of life is defined as functional abilities that include the ability to fulfill an individual social role, the degree and quality of social interaction, mental health, physical competence, somatic senses such as pain, and satisfaction with life. The World Health Organization (WHO) defined quality of life in 1947 as a decrease not only in disease, disorder or disability, but also in physical, mental and social well-being. Old age is one of the situations in which the quality of life decreases. It is reported that the poor social and financial situation of individuals, low educational level, gender, lack of physical movement, decreased daily life activity level, decreased mobility ability, fall anxiety, sleep problems and other conditions that cause disability are determinants of the quality of life. According to the results of Bloom et al.'s study, elderly people wake up at night due to health problems.
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According to the literature, the sleep and life of pet therapy applied to elderly individuals living in a nursing home there have not been any studies examining the effect on quality. For this reason, it was aimed to conduct this study in order to determine the effect of pet therapy applied to elderly individuals living in a nursing home on sleep and quality of life.
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The study was planned to be conducted in a randomized controlled manner in order to determine the effect of pet therapy applied for one hour twice a week for 6 weeks to elderly people living in a nursing home in Tokat province on sleep pattern and quality of life. In the study, gender, age group and the presence of chronic diseases were taken as equivalence criteria. Since conducting the study single-blind will increase the reliability of the study, the application of the scales was applied by another researcher/surveyor other than the main researcher. conditions: Pet Therapy Effect of Sleep and Quality of Life studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized controlled trial (Two groups with intervention and control group) primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: A pollster who did not know the people in the control and intervention group was selected and collected the data. The SPSS data were entered by someone selected other than the surveyor and the researcher. Thus, the study was conducted as a double-blind. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 59 type: ACTUAL name: Pet Therapy measure: PUKI measure: CASP-19 QUALITY OF LIFE sex: ALL minimumAge: 55 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Nursing Home city: Tokat state: Center zip: 60000 country: Turkey lat: 40.31389 lon: 36.55444 hasResults: False
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<|newrecord|> nctId: NCT06292377 id: BRUFAST briefTitle: Better Understanding of Fatigue After STroke overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-03-01 date: 2026-03-01 date: 2024-03-05 date: 2024-03-05 name: Brugmann University Hospital class: OTHER briefSummary: Stroke is worldwide the second most common cause of death following heart attack and the leading cause of disability. Post-stroke fatigue (PSF) is a common complication after stroke and can be defined as 'an overwhelming exhaustion or tiredness, not related to exertion, which does not typically improve with rest'. Fatigue following stroke can be divided into early (\< 3 months) and late (\> 3 months) fatigue. PSF can have a considerable impact on a person's everyday activities and quality of life, participation in the rehabilitation process and levels of caregiver burden. Yet no efficient treatment exists to prevent or cure PSF because the pathophysiology remains unclear and seems to be multifaceted.
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Autonomic dysfunction is a common complication after stroke, associated with higher morbidity and mortality. An easy tool to measure the function of the autonomic nervous system (ANS) is heart rate variability (HRV), which is defined as the beat-to-beat variation of the heart rate (= interbeat interval (IBI)). It is the result of alterations in the sympathetic and parasympathetic nervous system. In recent systematic reviews, authors stipulate that HRV can be regarded as a prognostic factor for short- and long-term stroke outcomes. HRV can be derived from 24 hours, 5 minutes (short-term) and \< 5 minutes (ultra-short-term) measurements by applying time-domain and frequency-domain indices.
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Autonomic dysfunction has been related to chronic fatigue syndrome, in addition to fatigue in multiple sclerosis, Parkinson's disease and myasthenia gravis. However, to the best of our knowledge, the relationship between autonomic dysfunction and PSF has not yet been fully investigated.
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Fatigue is also common in cardiovascular diseases, especially in patients with heart failure (HF). HF can contribute to fatigue after stroke, independently of stroke.
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Cardiac complications after acute ischemic stroke (AIS), such as arrhythmias, cardiac dysfunction and myocardial injury, are frequent. The so-called 'stroke-heart syndrome', a concept introduced in 2018, describes a broad spectrum of cardiac changes observed in 10-20% of patients with AIS within the first month after stroke onset, with a peak in the first 72 hours. A dysregulation in the neural-cardiac control after stroke is suspected to be the cause of the cascade leading to cardiac complications, in which autonomic dysfunction and inflammation seem to be part of the underlying mechanism.
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Based on previous studies and by analogy with other neurological diseases, the investigators hypothesize that autonomic dysfunction following AIS contributes to PSF and that patients presenting heart failure as a complication following AIS have an increased risk of PSF.
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To confirm this hypothesis, the investigators will conduct a prospective, interventional study where patients who are hospitalized at the Stroke Unit, within 72 hours after stroke symptom onset, will be included. Evaluation will take place of (a) the relationship between autonomic dysfunction (HRV) and early and late PSF, and of (b) the relationship between cardiac dysfunction and early PSF and late PSF.
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There will also be an investigation into following elements:
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* the association between early and late PSF and (a) certain inflammatory markers at admission (CRP, NLR), (b) stroke localization and (c) baseline imaging markers of brain frailty.
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* the role of pre-existing fatigue + pre-existing or post-stroke newly diagnosed cognitive impairment, depression and sleep disturbances on the course of PSF. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: BASIC_SCIENCE masking: NONE count: 250 type: ESTIMATED name: ECG name: Transthoracic echography (TTE) name: Blood sampling measure: Heart rate variability (HRV) measure: Heart rate variability (HRV) measure: Heart rate variability (HRV) measure: Transthoracic echography (TTE) measure: Transthoracic echography (TTE) measure: Transthoracic echography (TTE) measure: Fatigue Severity Scale measure: Fatigue Severity Scale measure: Fatigue Severity Scale measure: N-terminal pro-brain natriuretic peptide (NT-proBNP) measure: N-terminal pro-brain natriuretic peptide (NT-proBNP) measure: N-terminal pro-brain natriuretic peptide (NT-proBNP) measure: cardiac troponin (cTnT) measure: Blood CRP level measure: Blood neutrophil-to-lymphocyte ratio (NLR) measure: Stroke localization in the brain measure: Fazekas scale measure: Global cortical atrophy scale measure: Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) measure: Presence for pre-existing fatigue (yes/no) measure: Duration of pre-existing fatigue measure: Patient Health Questionnaire-2 (PHQ-2) measure: Patient Health Questionnaire-2 (PHQ-2) measure: Patient Health Questionnaire-2 (PHQ-2) measure: Montreal Cognitive Assessment (MoCA) questionnaire measure: Montreal Cognitive Assessment (MoCA) score measure: Insomnia Severity Index (ISI) measure: Insomnia Severity Index (ISI) measure: Insomnia Severity Index (ISI) measure: Complete blood count abnormalities: yes/no measure: Renal insufficiency: yes/no measure: Electrolyte imbalance: yes/no measure: Abnormal liver enzymes: yes/no measure: Dyslipidemia: yes/no measure: Diabetes: yes/no measure: Thyroid disorder: yes/no measure: Iron deficiency: yes/no sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CHU Brugmann city: Brussels zip: 1020 country: Belgium name: Anissa OURTANI, MD role: CONTACT phone: 024754819 email: Anissa.OURTANI@chu-brugmann.be name: Anissa OURTANI role: PRINCIPAL_INVESTIGATOR lat: 50.85045 lon: 4.34878 facility: UZ Brussel city: Brussel zip: 1090 country: Belgium name: Sylvie De Raedt, MD role: CONTACT email: Sylvie.DeRaedt@uzbrussel.be name: Sylvie De Raedt role: PRINCIPAL_INVESTIGATOR lat: 50.85045 lon: 4.34878 hasResults: False
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<|newrecord|> nctId: NCT06292364 id: PGIDS/BHRC/23/106 briefTitle: Comparison of Retention Characteristics of Immediate vs Delayed Retainer Delivery Using 3D Digital Model Analysis overallStatus: RECRUITING date: 2023-11-05 date: 2024-11-05 date: 2024-12-05 date: 2024-03-05 date: 2024-03-05 name: Postgraduate Institute of Dental Sciences Rohtak class: OTHER briefSummary: Retention has been defined as "the holding of teeth following orthodontic treatment in the treated position for the period of time necessary for the maintenance of the result". Controversies regarding retention regime exist due to lack of high quality evidence regarding duration, type and timing of different type retainer.The present randomised controlled trial will be undertaken to assess the changes and compare if there is any difference in movement of teeth in post orthodontic treatment cases with immediate and delayed (post 7 days) delivery using beggs retainer and change in level of bone biomarker over 6 months period of retention . conditions: Relapse studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: immediate orthodontic retainer delivery name: delayed orthodontic retainer delivery measure: overjet measure: overjet measure: overjet measure: Overjet measure: contact point displacement measure: contact point displacement measure: contact point displacement measure: contact point displacement measure: overbite measure: overbite measure: overbite measure: overbite measure: intermolar width measure: intermolar width measure: intermolar width measure: intermolar width measure: intercanine width measure: intercanine width measure: intercanine width measure: intercanine width measure: GCF - elisa measure: GCF - elisa measure: GCF - elisa measure: GCF - elisa sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Pgids Rohtak status: RECRUITING city: Rohtak state: Haryana zip: 124001 country: India name: Dr. Rekha Sharma, MDS role: CONTACT phone: 8076190296 email: rajsringari@gmail.com lat: 28.89447 lon: 76.58917 hasResults: False
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<|newrecord|> nctId: NCT06292351 id: DMBN_ALZH-2022-II briefTitle: DMB-I in the Treatment of Alzheimer Type Dementia overallStatus: RECRUITING date: 2023-12-27 date: 2024-12-21 date: 2024-12-21 date: 2024-03-05 date: 2024-03-20 name: Bigespas LTD class: INDUSTRY briefSummary: The purpose of this study is to assess the efficacy and safety of DMB-I for the treatment of patients with Alzheimer type dementia. conditions: Alzheimer Disease conditions: Dementia of Alzheimer Type studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 135 type: ESTIMATED name: DMB-I (Dimebon) name: Placebo measure: Mean change in Alzheimer's Disease Assessment Scale score after 26 weeks of therapy (Visit 6) compared to baseline (Visit 0) in patients receiving the study drug or placebo measure: Mean change in cognitive impairment score on the Alzheimer's Disease Assessment Scale after 12 weeks of therapy compared to baseline measure: Mean change in Mini-Mental State Examination score after 12 weeks of therapy (Visit 4) and after 26 weeks of therapy (Visit 6) compared to baseline (Visit 0) measure: Change in the quality of life of patients according to the Quality of Life - Alzheimer's Disease questionnaire after 12 weeks of therapy (Visit 4) and after 26 weeks of therapy (Visit 6) compared to baseline (Visit 1) measure: Change in the general clinical impression in accordance with the Clinical Global Impressions Scale after 12 weeks of therapy (Visit 4) and after 26 weeks of therapy (Visit 6) compared to baseline (Visit 1) measure: Dynamics on the Lawton's Instrumental activities of daily living scale after 12 weeks of therapy (Visit 4) and after 26 weeks of therapy (Visit 6) compared to baseline (Visit 1) sex: ALL minimumAge: 60 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: State autonomous healthcare institution "Transregional Clinical Diagnostic Center" status: RECRUITING city: Kazan zip: 420101 country: Russian Federation name: Dina Khasanova role: CONTACT email: Icdc@icdc.ru lat: 55.78874 lon: 49.12214 facility: Federal State Budgetary Institution "Federal center for brain and neurotechnologies" of the Federal Medical and Biological Agency (FSBI "FCBN" of Russia's FMBA) status: RECRUITING city: Moscow zip: 117997 country: Russian Federation name: Anna N. Bogolepova role: CONTACT email: annabogolepova@yandex.ru lat: 55.75222 lon: 37.61556 facility: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) status: RECRUITING city: Moscow zip: 119991 country: Russian Federation name: Marina A. Kinkulkina role: CONTACT email: Kinkulkina_m_a@staff.sechenov.ru lat: 55.75222 lon: 37.61556 facility: State public healthcare institution Leningrad regional psychoneurologic dispensary status: RECRUITING city: Roshchino zip: 188820 country: Russian Federation name: Natalia A. Penchul role: CONTACT email: penchul@inbox.ru lat: 60.25191 lon: 29.6085 facility: "Medical Center Nova Vita" status: RECRUITING city: Rostov-on-Don zip: 344082 country: Russian Federation name: Dhaval Mavani role: CONTACT email: mavani_dhaval@yahoo.com lat: 47.23135 lon: 39.72328 facility: Saint Petersburg State budgetary healthcare institution "City Hospital № 40 of Kurortniy district" status: RECRUITING city: Saint Petersburg zip: 197706 country: Russian Federation name: Alina S Agaf'yina role: CONTACT email: a.agafina@mail.ru lat: 59.93863 lon: 30.31413 facility: "Centre of evidence-based medicine" LLC status: RECRUITING city: Yaroslavl zip: 150000 country: Russian Federation name: Stanislav O. Pozdnyakov role: CONTACT email: sopozdnyakov@yandex.ru lat: 57.62987 lon: 39.87368 hasResults: False
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<|newrecord|> nctId: NCT06292338 id: AUCHAU briefTitle: Lung Sonar in Neonatal Respiratory Disorders overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-05-01 date: 2024-03-05 date: 2024-03-05 name: Gehad Adel Mohammed Hussein class: OTHER briefSummary: This study aimed to determine the value of chest ultrasonography in comparison to other tools as chest x-ray and ABG in diagnosis and follow up of neonates with respiratory disorders. conditions: Neonatal Respiratory Distress studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 1 type: ESTIMATED measure: Comparing between LUS and Chest xRay in neonatal respiratory disorders assessment sex: ALL minimumAge: 1 Day maximumAge: 28 Days stdAges: CHILD hasResults: False
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<|newrecord|> nctId: NCT06292325 id: FDG_88-17 briefTitle: Psychological Aspects in OSA acronym: PSICOSA overallStatus: ENROLLING_BY_INVITATION date: 2023-05-08 date: 2023-05-08 date: 2024-05-31 date: 2024-03-05 date: 2024-03-07 name: Fondazione Don Carlo Gnocchi Onlus class: OTHER name: Catholic University of the Sacred Heart briefSummary: The research project consists of an observational study. Obstructive Sleep Apnea (OSA) is a condition characterized by recurrent episodes of upper airway collapse during sleep, leading to decreased blood oxygen levels and disruptions of normal sleep patterns. Estimates of its prevalence vary, but its impact on patients' quality of life is evident.
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The research aims to explore the perception and awareness of the disease and its impact on the individual and couple's lives of patients with OSA and their bed partners, to assess patients' perceptions of the disease and symptoms, as well as their bed partners' perceptions. Moreover, psychological aspects of living with OSA, such as perceived stress, depression, anxiety, sleep quality, daily sleepiness will be studied to observe the association with Continuous Positive Airway Pressure (CPAP) adherence. conditions: Osa Syndrome studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 246 type: ESTIMATED name: Continuous Positive Airway Pressure (CPAP) measure: Brief Illness Perception Questionnaire (Brief IPQ) measure: CPAP therapy adherence (hours/night) measure: Dyadic Adjustment Scale (DAS) measure: The experience in close relationships-revised (ECR-R) Scale measure: The Psychological General Well-Being Index (PGWB-S) measure: The Patient Health Questionnaire - 9 (PHQ-9) measure: The Generalized Anxiety Scale -7 (GAD-7) measure: The Mannheim Dream Questionnaire (MADRE) measure: The EP worth scale (ESS) measure: Pittsburgh Sleep Quality Index (PSQI) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Fondazione Don Carlo Gnocchi city: Milan state: MI zip: 20148 country: Italy lat: 45.46427 lon: 9.18951 hasResults: False
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<|newrecord|> nctId: NCT06292312 id: 19.12.2023/10-483 briefTitle: Investigation of the Effectiveness of Craniosacral Therapy in Patients With Multiple Sclerosis. overallStatus: RECRUITING date: 2024-02-27 date: 2025-04-15 date: 2025-05-15 date: 2024-03-05 date: 2024-03-05 name: Ankara Yildirim Beyazıt University class: OTHER name: Lokman Hekim Üniversitesi briefSummary: Although the cause of Multiple Sclerosis (MS), one of the common demyelinating diseases of the central nervous system, has not yet been fully elucidated, autonomic nervous system dysfunction has been suggested in its etiology. Symptoms such as fatigue, problems with bladder, bowel, cardiovascular, sleep, sexual and sweating functions, abnormal sympathetic skin response or decreased heart rate variation support this hypothesis.
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In the treatment of many neurological diseases such as Multiple Sclerosis, complementary medicine practices and non-traditional therapies have recently been shown to be effective in addition to conventional practices. One of these practices, craniosacral therapy (CST), uses manual palpation and manipulation of the craniosacral system to influence sensory, motor, cognitive and emotional processes in the nervous system. In addition, it is thought that applying external force to certain bone elements can have a positive effect on various symptoms in patients with MS, based on the knowledge that it can be transmitted within the system. conditions: Multiple Sclerosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: dual parallel group design primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Single (outcomes assesor) The evaluation of the patients will be carried out by a blinded investigator. whoMasked: OUTCOMES_ASSESSOR count: 32 type: ESTIMATED name: Craniosacral therapy name: Conventional physiotherapy measure: Dynamic posturography measure: Heart rate variability measure: Pain level measure: Central sensitization measure: Fatigue measure: Sleep quality measure: Life quality sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ankara Yıldırım Beyazıt University status: RECRUITING city: Ankara zip: 06010 country: Turkey name: Hilal Aslan role: CONTACT phone: 05372565397 email: hilalaslan@aybu.edu.tr lat: 39.91987 lon: 32.85427 hasResults: False
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<|newrecord|> nctId: NCT06292299 id: INGN22RM471P id: 10072600 type: OTHER_GRANT domain: PneumoWave Ltd & Innovate UK briefTitle: The PARS Study: Paediatric Advanced Respiratory Service Study - An Observational Diagnostic Feasibility Study acronym: PARS overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-12 date: 2025-12 date: 2024-03-05 date: 2024-03-05 name: NHS Greater Clyde and Glasgow class: OTHER name: INNOVATEUK briefSummary: Diagnostic investigations in paediatric respiratory and sleep medicine are often challenging due to patient size (due to prematurity), tolerability, and compliance with "gold standard equipment". Children with sensory/behavioural issues, at increased risk of sleep disordered breathing (SDB), often find tolerating standard diagnostic equipment difficult. There is a need to develop non-invasive, wireless, devices designed for the paediatric population. Devices must address health in-equalities as high-risk children, with low birth weights, genetic syndromes, or complex neuro-disabilities, are often unable to undergo current investigations, particularly in sleep medicine. Prompt and accurate diagnosis of SDB is important to facilitate early intervention and improve outcomes
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Infants in the neonatal period can have immature breathing control which manifests as excessive central breathing pauses, apnoea's, whilst asleep requiring oxygen therapy. There is also a risk to newborn term infants of sudden unexpected neonatal collapse, even in "low risk" babies. Diagnosis of breathing issues in babies can be challenging since babies are often too small for standard monitoring equipment. Effective monitoring and appropriate treatment of apnoea's has been shown to improve prognosis in terms of 5-year mortality and neurodevelopmental outcomes.
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This observational study is part of a phased clinical program of research that aims to validate a small wearable biosensor developed by PneumoWave Ltd in a paediatric clinical setting with the overall primary endpoints of monitoring and assessing respiratory pattern as an aid to sleep diagnostics, and as a device to monitor apnoea in neonatal patients. conditions: Sleep Disordered Breathing conditions: Apnea of Prematurity conditions: Respiratory Rate studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 150 type: ESTIMATED name: Pneumowave measure: Assess the feasibility of collecting respiratory waveform data using Pneumowave device in patients who have (1) attended the sleep laboratory for CR- polysomnography and (2) are inpatient in neonatal unit measure: Collate respiratory data in patients who have attended the sleep laboratory for CR- poly or inpatient in neonatal unit. Respiratory data will observe: (1) Normal respiratory effort (2) Response to treatments measure: Collate waveform and motion artefact data in patients who have attended overnight CR-polysomnography measure: Collate waveform and motion artefact data in neonatal patients at risk of central apnoea measure: Assess the useability of Pneumowave in the opinion of the clinician, nurse and patient sex: ALL minimumAge: 1 Minute maximumAge: 16 Years stdAges: CHILD facility: Royal Hospital for Children, Glasgow city: Glasgow state: Glasgow City zip: G51 4TF country: United Kingdom name: Ross J Langley, MBChB BSc PhD MRCPCH role: CONTACT phone: 0141 451 6582 email: ross.langley@ggc.scot.nhs.uk name: Hannah Vennard, MBChB BMSc role: CONTACT phone: 0141 451 6582 email: hannah.vennard@ggc.scot.nhs.uk lat: 55.86515 lon: -4.25763 facility: Royal Hospital for Children, Glasgow city: Glasgow zip: G51 4TF country: United Kingdom lat: 55.86515 lon: -4.25763 hasResults: False
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<|newrecord|> nctId: NCT06292286 id: UW 22-704 briefTitle: Secondary Interval Cytoreductive Surgery in Platinum-sensitive Recurrent Epithelial Ovarian Cancer acronym: SCENIC overallStatus: RECRUITING date: 2023-11-01 date: 2025-12-31 date: 2026-07-01 date: 2024-03-05 date: 2024-03-05 name: The University of Hong Kong class: OTHER briefSummary: About 80% of advanced ovarian cancer patients recurred in 2-3 years. Secondary cytoreduction benefits selected patients who have high chance of complete resection. Whether secondary interval surgery can be used at recurrence is not known. conditions: Recurrent Ovarian Carcinoma studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Neoadjuvant carboplatin and paclitaxel followed by cytoreductive surgery primaryPurpose: TREATMENT masking: NONE count: 18 type: ESTIMATED name: Carboplatin or cisplatin name: Paclitaxel, gemcitabine or liposomal doxorubicin with or without bevacizumab or biosimilar name: Bevacizumab or biosimilar name: Cytoreductive surgery measure: Complete resection rate measure: 12-month progression-free survival rate measure: 12-month overall survival rate measure: Surgical complication rate measure: Quality of life scale sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The University of Hong Kong status: RECRUITING city: Hong Kong country: Hong Kong name: Lesley Lau role: CONTACT phone: 852-22554518 name: Ka Yu Tse role: CONTACT phone: 852-22554265 email: tseky@hku.hk name: Ka Yu Tse, MBBS, PhD role: PRINCIPAL_INVESTIGATOR lat: 22.27832 lon: 114.17469 hasResults: False
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<|newrecord|> nctId: NCT06292273 id: ANET19 briefTitle: Bupivacaine With Dexmedetomidine Versus Bupivacaine Alone for Transversus Abdominis Plane Block in Caesarean Section overallStatus: COMPLETED date: 2023-10-10 date: 2024-02-01 date: 2024-02-20 date: 2024-03-05 date: 2024-03-05 name: Menoufia University class: OTHER briefSummary: Transversus Abdominis plane (TAP) block is a regional technique for providing analgesia of the anterolateral abdominal wall. TAP block are commonly given in patients who have undergone various abdominal as well as pelvic surgeries such as caesarean section, hysterectomy, appendicectomy and various laparoscopic surgeries. this study is conducted to analyse the effect of addition of dexmedetomidine to bupivacaine in Transversus Abdominis Plane (TAP) block. conditions: Post Operative Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomized, double blind case control primaryPurpose: PREVENTION masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ACTUAL name: Transversus Abdominis Plane Block with bupivacain Plus dexamethasone name: Transversus Abdominis Plane Block with bupivacain measure: Post operative pain measure: Sedation measure: Heart rate measure: Total analgesic consumption measure: Side effects sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Faculty of Medicine Menoufia University city: Cairo state: Governorate zip: 32511 country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
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<|newrecord|> nctId: NCT06292260 id: 2020-2054-2 briefTitle: Digital Toolkit for Skin Diseases in LMICs: Part 2 acronym: MIND-the-SKIN2 overallStatus: RECRUITING date: 2024-03-18 date: 2026-05-31 date: 2026-05-31 date: 2024-03-05 date: 2024-04-17 name: Tulane University class: OTHER name: Hope Commission International name: Institut Pasteur of Cote d'Ivoire name: Institut Raoul Follereau name: Centre Suisse de Recherches Scientifiques en Cote d'Ivoire name: Tokyo Medical and Dental University briefSummary: Impact evaluation of eSkinHealth in improving case detection of skin NTDs and treatment outcomes in rural and urban settings conditions: Skin Diseases studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 1000 type: ESTIMATED name: mHealth app measure: Number of cases of each skin NTD (neglected tropical disease) and other skin conditions as compared to the pre-intervention measure: Case confirmation rate for each skin NTD (neglected tropical disease) and other skin conditions by dermatologists measure: Number of days from registry to confirmatory diagnosis measure: Feasibility, usability, and effectiveness of the surveillance approach using eSkinHealth app measure: Capacity building and effectiveness of training sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hope Commission International status: RECRUITING city: Abidjan country: Côte D'Ivoire name: Aubin Yao, MS role: CONTACT email: aubin@hopecommission.org name: Eric-Herman N'da Kouakou role: CONTACT email: ekouakou@hopecommission.org name: Bamba Vagamon, MD, PhD role: PRINCIPAL_INVESTIGATOR lat: 5.30966 lon: -4.01266 hasResults: False
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<|newrecord|> nctId: NCT06292247 id: A0503023 briefTitle: Effectiveness of CBT and APT on Managing Child Anxiety in Dental Office overallStatus: ACTIVE_NOT_RECRUITING date: 2023-06-01 date: 2023-10-23 date: 2024-05-01 date: 2024-03-05 date: 2024-03-07 name: Mansoura University class: OTHER briefSummary: This study was conducted to the Effectiveness of Cognitive Behavioral Therapy and Auricular Plaster Therapy on Managing Child Anxiety in Dental Office. conditions: Dental Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Group 1 (CBT) Group 2 (APT) Group3 (control TSD) primaryPurpose: OTHER masking: NONE count: 60 type: ESTIMATED name: Cognitive behavioral therapy name: Auricular plaster therapy name: Tell Show Do measure: Venham Clinical Anxiety Scale measure: Heart Rate to detect the anxiety. measure: RMS-Self Pictorial scale to detect the anxiety. measure: Parental acceptance of the behavior management technique sex: ALL minimumAge: 4 Years maximumAge: 7 Years stdAges: CHILD facility: Faculty of dentistry city: Mansoura state: Dakahlia zip: 35511 country: Egypt lat: 31.03637 lon: 31.38069 hasResults: False
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<|newrecord|> nctId: NCT06292234 id: OMFS briefTitle: Patient Specific Implant Versus Miniplates for Advancement of Hypoplastic Maxilla overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-02-01 date: 2025-03-01 date: 2024-03-05 date: 2024-04-19 name: Cairo University class: OTHER briefSummary: Distraction osteogenesis is the treatment of choice in management of severe maxillary anteroposterior deficiency allowing for a progressive bone generation and simultaneous expansion of the surrounding scarred soft tissue \& better long-term stability \& less relapse rate. conditions: Cleft Lip and Palate studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Parallel randomized controlled trial with 1:1 allocation ratio and superiority framework primaryPurpose: TREATMENT masking: SINGLE maskingDescription: single blinded clinical trial whoMasked: PARTICIPANT count: 20 type: ESTIMATED name: PSI name: Conventional miniplates measure: Distraction effectiveness measure: Velopharyngeal insufficiency measure: Speech measure: Operative time measure: Wound dehiscence measure: Infection measure: Nerve affection measure: Screw loosening measure: Overall complications sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT hasResults: False
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<|newrecord|> nctId: NCT06292221 id: H19-078 id: R01MH119678 type: NIH link: https://reporter.nih.gov/quickSearch/R01MH119678 briefTitle: Personalized Depression Treatment Supported by Mobile Sensor Analytics acronym: DepWatch overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-04 date: 2025-06 date: 2024-03-05 date: 2024-03-05 name: UConn Health class: OTHER name: National Institute of Mental Health (NIMH) briefSummary: The current best practice guidelines for treating depression call for close monitoring of patients, and periodically adjusting treatment as needed. This present study seeks to develop and investigate an innovative digital system, DepWatch, that leverages mobile health technologies and machine learning tools to provide clinicians objective, accurate, and timely assessment of depression symptoms to assist with their clinical decision making process. Specifically, DepWatch collects sensory data passively from smartphones and wristbands, without any user interaction, and uses simple user-friendly interfaces to collect ecological momentary assessments (EMA), medication adherence and safety related data from patients. The collected data will be fed to machine learning models to be developed in the project to provide weekly assessment of patient symptom levels and predict the trajectory of treatment response over time. The assessment and prediction results are then presented using a graphic interface to clinicians to help them make critical treatment decisions. The main question the present clinical trial aims to answer are as follows:
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1. Feasibility of the digital tool, DepWatch, to assist clinicians in depression treatment and inform their clinical decision process
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2. Effectiveness of the digital tool, DepWatch, to improve depression treatment outcomes All study participants will carry the DepWatch app on their smartphones and wear a Fitbit provided by the study team during the study period. They will also complete brief questionnaires via the app at specific time intervals throughout the study period. conditions: Depression studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Two groups of participants (64 per group) will be enrolled and will participate in the study over a 3 month period . Both will receive standard of care depression treatment with their respective providers in the clinic. Both groups will undergo standard depression assessment using depression questionnaires as well as behavioral assessments using a mobile health (mHealth) tool 'DepWatch' developed by the study team in the phase I of the study. Study clinicians will receive weekly behavioral assessment reports for participants enrolled in the first 'experimental' group and will not receive such reports for the second 'control' group primaryPurpose: DIAGNOSTIC masking: NONE maskingDescription: There is no masking count: 128 type: ESTIMATED name: A mobile Health (mHealth) tool called 'DepWatch' measure: Feasibility and Usability measure: Depression outcomes sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
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<|newrecord|> nctId: NCT06292208 id: IBD0333-101 briefTitle: A Clinical Trial to Evaluate Effect of IBD0333 in Patients With Advanced Malignant Tumors overallStatus: NOT_YET_RECRUITING date: 2024-03-02 date: 2029-12-31 date: 2030-12-31 date: 2024-03-05 date: 2024-03-05 name: SUNHO(China)BioPharmaceutical CO., Ltd. class: INDUSTRY briefSummary: Primary Objectives Dose escalation phase To evaluate the safety and tolerability of IBD0333 in patients with locally advanced/metastatic solid tumor or non-Hodgkin lymphoma and to determine the maximum tolerated dose (MTD), extended recommended dose (DRDE), and/or dose limiting toxicity (DLT).
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Dose expansion phase To evaluate the safety and tolerability of IBD0333 in patients with locally advanced/metastatic solid tumor or non-Hodgkin lymphoma and to determine the recommended Phase 2 dose (RP2D).
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Clinical exploration phase To evaluate the preliminary efficacy of IBD0333 in patients with specific tumor.
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Secondary objectives Dose escalation phase \& Dose expansion phase To evaluate the pharmacokinetic (PK) of IBD0333 in patients with locally advanced/metastatic solid tumor or non-Hodgkin lymphoma; To evaluate the immunogenicity of IBD0333 in patients with locally advanced/metastatic solid tumor or non-Hodgkin lymphoma; To evaluate the preliminary efficacy of IBD0333 in patients with locally advanced/metastatic solid tumor or non-Hodgkin lymphoma.
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Clinical exploration Phase To evaluate the safety and tolerability of IBD0333 in patients with specific tumor; To evaluate the immunogenicity of IBD0333 in patients with specific tumor. Exploratory Objectives To explore biomarkers in blood and tissue that predict potential efficacy of IBD0333. conditions: MTD studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 48 type: ESTIMATED name: IBD0333 measure: MTD measure: DRDE measure: Dose limiting toxicity (DLT) measure: RP2D measure: ORR measure: pharmacokinetic parameters measure: pharmacokinetic parameters measure: pharmacokinetic parameters measure: pharmacokinetic parameters measure: ADA measure: ORR measure: DCR measure: DoR measure: PFS measure: Frequency of adverse events (AEs) and SAEs sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
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<|newrecord|> nctId: NCT06292195 id: VitDTracking briefTitle: Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome acronym: VitDTracking overallStatus: RECRUITING date: 2023-11-03 date: 2024-12-31 date: 2025-12-31 date: 2024-03-05 date: 2024-03-05 name: University of Évora class: OTHER name: Comprehensive Health Research Centre name: Unidade Local De Saúde Do Norte Alentejano name: Unidade local de Saúde do Baixo Alentejano name: Unidade Local de Saúde do Alentejo Central name: Universidade Nova de Lisboa name: Instituto de Engenharia de Sistemas e Computadores - Inovação e Desenvolvimento de Lisboa (INESC-ID) briefSummary: The VitDTracking study focuses on the relevance of maternal vitamin D levels and their association with prematurity, aiming to improve maternal and child health outcomes, particularly by reducing avoidable preterm births. In Portugal, vitamin D levels during pregnancy have never been studied. Epidemiological data from other countries reveal a high prevalence of vitamin D deficiency/insufficiency, especially in pregnant women.
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The hypovitaminoses prevalence remains high even with a supplementation dosage of 400 to 600 IU/day during pregnancy (dosage used in Portugal), which is considered as a suboptimal dose. This phenomenon is associated with adverse maternal and child outcomes, such as intrauterine growth restriction, preeclampsia, cholestasis, hypertension, and gestational diabetes as major causes of prematurity.
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Additionally, the Portuguese population has a higher prevalence of genome alterations that confer a lower capacity to produce vitamin D from sunlight exposure. These genetic characteristics are present in about 19% of the population, representing a prevalence four times higher than the European average (19% versus 4.75%), leading to a higher predisposition to vitamin D deficiency. conditions: Vitamin D Deficiency conditions: Pregnancy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1000 type: ESTIMATED name: Exposure measure: Differences in the rate of Prematurity with different maternal Vitamin D levels measure: Differences in Birth Weight with different maternal Vitamin D levels measure: Differences in Apgar Scores with different maternal Vitamin D levels measure: Differences in the number of admissions to the Neonatal Intensive Care Unit with different maternal Vitamin D levels measure: Differences in the Neonatal Morbidity rate with different maternal Vitamin D levels measure: Differences in the Neonatal Mortality rate with different maternal Vitamin D levels measure: Differences in the number of Neonatal Infections with different maternal Vitamin D levels measure: Differences in the Number of Congenital Malformation diagnoses with different maternal vitamin D levels measure: Differences in the presence of vitamin D-related polymorphisms with different maternal levels of vitamin D measure: Differences in maternal vitamin D levels between the three groups/cohorts related to prematurity measure: Differences in maternal vitamin D levels between the three groups/cohorts related to birth weight measure: Differences in maternal vitamin D levels between the three groups/cohorts related to Apgar scores measure: Differences in maternal vitamin D levels between the three groups/cohorts related to admission to the Neonatal Intensive Care Unit measure: Differences in maternal vitamin D levels between the three groups/cohorts related to neonatal morbidity measure: Differences in maternal vitamin D levels between the three groups/cohorts related to neonatal mortality measure: Differences in maternal vitamin D levels between the three groups/cohorts related to neonatal infections. measure: Differences in maternal vitamin D levels between the three groups/cohorts related to the diagnosis of congenital malformations measure: Differences in the presence of vitamin D-related polymorphisms between the three groups/cohorts associated with prematurity measure: Differences in the presence of vitamin D-related polymorphisms between the three groups/cohorts associated with birth weight measure: Differences in the presence of vitamin D-related polymorphisms between the three groups/cohorts associated with Apgar scores measure: Differences in the presence of vitamin D-related polymorphisms between the three groups/cohorts associated with admission to the Neonatal Intensive Care Unit. measure: Differences in the presence of vitamin D-related polymorphisms between the three groups/cohorts associated with neonatal morbidity measure: Differences in the presence of vitamin D-related polymorphisms between the three groups/cohorts associated with neonatal mortality measure: Differences in the presence of vitamin D-related polymorphisms between the three groups/cohorts associated with neonatal infections measure: Differences in the presence of vitamin D-related polymorphisms between the three groups/cohorts associated with the diagnosis of congenital malformations sex: FEMALE minimumAge: 16 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Unidade Local de Saúde do Baixo Alentejo status: RECRUITING city: Beja zip: 7801-849 country: Portugal name: Inês Gornilho, MD role: CONTACT email: ines.gornilho@ulsba.min-saude.pt lat: 38.01506 lon: -7.86323 facility: Unidade Local de Saúde do Norte Alentejano status: RECRUITING city: Portalegre zip: 7301-853 country: Portugal name: Vera Escoto, MD role: CONTACT email: veraescoto.ca@ulsaale.min-saude.pt lat: 39.29379 lon: -7.43122 facility: Unidade Local de Saúde do Alentejo Central - Hospital Espirito Santo de Évora status: RECRUITING city: Évora zip: 7000-811 country: Portugal name: Maria OP Barbosa, MSc; PhD Student role: CONTACT phone: 00351966056178 email: mobarbosa@hevora.min-saude.pt name: Fernando Fernandes, MD role: CONTACT phone: 00351965753123 email: ffernandes@hevora.min-saude.pt lat: 38.56667 lon: -7.9 hasResults: False
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<|newrecord|> nctId: NCT06292182 id: 160802 id: 332942 type: OTHER domain: IRAS id: 58964 type: OTHER domain: CPMS briefTitle: Red Light Ptosis Proof-of-Concept overallStatus: RECRUITING date: 2024-02-08 date: 2025-11-30 date: 2025-11-30 date: 2024-03-05 date: 2024-03-05 name: University College, London class: OTHER name: Moorfields Eye Hospital NHS Foundation Trust briefSummary: This study tests a new treatment to help with droopy eyelids (ptosis) and eye movement problems (squint) in children and young people with genetically confirmed mitochondrial conditions - using red-light.
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We use a torch to shine a red light through the closed eyelid for 3 minutes a day. The study will run for 18 months.
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We believe that this treatment could help strengthen the muscle in the eyelid to make it easier to open the eyes, and could also help some children with squint. conditions: Mitochondrial Diseases conditions: Blepharoptosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 10 type: ESTIMATED name: Near-infrared light measure: Palpebral fissure width sex: ALL minimumAge: 3 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Moorfields Eye Hospital NHS Foundation Trust status: RECRUITING city: London zip: EC1V 2PD country: United Kingdom name: Annegret H Dahlmann-Noor, PhD role: CONTACT phone: 020 7253 3411 email: annegret.dahlmann-noor@nhs.net lat: 51.50853 lon: -0.12574 hasResults: False
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<|newrecord|> nctId: NCT06292169 id: STUDY00007201 briefTitle: Pectoralis Minor Release Versus Non-release in RSA overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-01 date: 2026-01 date: 2024-03-05 date: 2024-04-09 name: Emory University class: OTHER briefSummary: The goal of this clinical trial is to assess if concomitant open pectoralis minor release would improve pain and outcomes after Reverse Shoulder Arthroplasty (RSA). The main questions it aims to answer are:
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* whether releasing the pectoralis minor prophylactically could have better pain relief
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* whether releasing the pectoralis minor prophylactically could have increased Range of motion (ROM) outcomes
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* whether releasing the pectoralis minor prophylactically could have higher final Patient Reported Outcome Measurements (PROMs) Participants will be randomized to either undergo RSA with pectoralis minor release or RSA without pectoralis minor release. conditions: Reverse Total Shoulder Arthroplasty conditions: Rotator Cuff Tear Arthropathy conditions: Advanced Glenohumeral Osteoarthritis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Electronic random number generator Single-blinded (concealed to the study participant only, Investigator blinded not feasible) whoMasked: PARTICIPANT count: 30 type: ESTIMATED name: Pectoralis Minor Release name: RSA measure: Visual analog Scale (VAS) pain scores measure: Visual analog Scale (VAS) pain scores measure: American Shoulder and Elbow Score (ASES) measure: Subjective Shoulder Value (SSV) measure: Change in Range of motion (ROM) measure: Change in Scapulohumeral Rhythm (SHR) on Digital Dynamic Radiography (DDR) measure: Number of complications measure: Number of reoperations sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Emory Clinic city: Atlanta state: Georgia zip: 30322 country: United States name: Eric Wagner, MD role: CONTACT phone: 404-778-7249 email: eric.r.wagner@emory.edu name: Musab Gulzar role: CONTACT phone: 201-344-0298 email: mgulzar@emory.edu name: Michael Gottschalk, MD role: SUB_INVESTIGATOR lat: 33.749 lon: -84.38798 facility: Emory Healthcare Orthopaedics and Spine Center city: Atlanta state: Georgia zip: 30329 country: United States name: Eric Wagner, MD role: CONTACT phone: 404-778-7249 email: Eric.r.wagner@emory.edu name: Musab Gulzar role: CONTACT phone: 201-344-0298 email: mgulzar@emory.edu lat: 33.749 lon: -84.38798 hasResults: False
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<|newrecord|> nctId: NCT06292156 id: CASPsy7 briefTitle: tACS Treatment for Cognitive Impairments in Methamphetamine Addicts overallStatus: RECRUITING date: 2023-02-20 date: 2024-08 date: 2024-08 date: 2024-03-04 date: 2024-03-04 name: Beijing HuiLongGuan Hospital class: OTHER briefSummary: 1. To evaluate the cognitive function of methamphetamine Patients.
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2. Investigate the pathological mechanism of methamphetamine patients from the aspects of EEG and biology;
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3. The investigators investigated the effects of transcranial alternating current stimulation (tACS) on cognitive impairments in methamphetamine patients conditions: Methamphetamine Abuse studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 300 type: ESTIMATED name: Theta treatment group name: Alpha active control group name: Sham control group measure: The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) measure: ERP components associated with cognitive function measure: Condition stop signal task measure: Neural oscillations associated with cognitive function measure: Functional connection of brain region associated with cognitive function measure: Microstate associated with cognitive function measure: The effect of oxidative stress system on cognitive function measure: The effect of immune system on cognitive function measure: The effect of brain derived neurotrophic factor(BDNF) on cognitive function measure: Genetic mechanism of cognitive function measure: Reverse learning task measure: Beck Depression Scale measure: Barrett impulse Scale measure: Degree of insomnia measure: The Sensitivity to Punishment and Reward Questionnaire measure: Visual analog scale measure: The Desires for Drug Questionnaire measure: Obsessive compulsive drug use scale measure: Obsessive-compulsive inventory measure: Thought Control Ability Questionnaire measure: Thought Suppression Questionnaire measure: Rumination Questionnaire measure: Anger Rumination Questionnaire measure: Beck Anxiety Scale measure: Emotional Regulation Difficulty Scale measure: Aggressive questionnair sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Xin Hua Drug Rehabilitation Center status: RECRUITING city: Mianyang country: China name: China role: CONTACT lat: 31.46784 lon: 104.68168 hasResults: False
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<|newrecord|> nctId: NCT06292143 id: EU101136769-CLIN2 briefTitle: AI4HOPE Dementia Care Planning Pilot Study 2 ( AI4HOPE2) acronym: AI4HOPE-P2 overallStatus: NOT_YET_RECRUITING date: 2025-07 date: 2026-12 date: 2026-12 date: 2024-03-04 date: 2024-03-04 name: University of Bonn class: OTHER name: University College Cork name: University of Leeds name: Fundacion Intras name: Universidade do Porto name: University Medical Centre Maribor briefSummary: This pilot study will test a digital care planning decision support system for patients with dementia. conditions: Dementia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Feasibility study primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 150 type: ESTIMATED name: Advance Care Planning Toolkit measure: Ease of use of digital platform measure: Effect of digital platform on documentation of advance care planning sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Bonn city: Bonn zip: 53127 country: Germany lat: 50.73438 lon: 7.09549 hasResults: False
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<|newrecord|> nctId: NCT06292130 id: 156588-01 briefTitle: Health-Kit Enabled Mobile App for Tobacco Cessation overallStatus: COMPLETED date: 2022-03-21 date: 2023-09-21 date: 2023-09-21 date: 2024-03-04 date: 2024-03-04 name: Pro-Change Behavior Systems class: OTHER briefSummary: Tobacco use remains the leading preventable cause of death in the US, contributing to more than 480,000 premature deaths each year. The Tobacco Treatment Guidelines underscore the need to offer patients who use tobacco products brief interventions that include prescriptions for proven pharmacological smoking cessation aids and proactive connections to evidence-based behavioral support. The rapid expansion of smart phone capabilities enhances the potential for tobacco cessation apps to personalize behavior change guidance and to send contextually relevant tailored behavior change nudges based on readiness to quit and electronic heath record (EHR) data. Rich data from EHRs are now available to third-party apps from the Health app (iOS) via Fast Healthcare Interoperability Resources standard Application Programming Interface (API).
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This Phase I SBIR will explore the acceptability and effects of one such innovative health IT solution. Refresh is a highly individualized tobacco cessation HealthKit enabled app that will 1) implement a full range of best practices in tailored health behavior change communications based on readiness to change; 2) individualize behavior change guidance based on Health app data; and 3) concisely provide data and documentation of key actionable insights in the EHR on the patient's smoking status, app usage, and brief micro-message clinicians can deliver to reinforce and accelerate a patient's behavior change progress. This interoperability will provide value to both patients and clinicians; empower and support successful and lasting behavior change; and enable the implementation and evaluation of a best-in-class approach to tobacco and nicotine treatment.
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Extensive end user and stakeholder input will ensure refresh is designed for rapid dissemination. Patients of an integrated delivery system with an upcoming appointment (n=100) will be recruited to participate in a 30-day pilot test. Pilot participants will provide quantitative and qualitative data, and utilization and acceptability data will be examined. Pre-post comparisons of PROMIS measure for tobacco (psychosocial expectancies) will provide preliminary data on the effects of the program. Acceptability data from participating clinicians (n=10) who receive and deliver EHR prompts will also be gathered. The hypothesis is that the patients who utilize refresh will have significantly higher psychosocial expectancies regarding tobacco at follow-up. Secondary outcomes will be examined. conditions: Cigarette Smoking studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single group, repeated measures (2 timepoints) primaryPurpose: TREATMENT masking: NONE count: 51 type: ACTUAL name: refresh measure: Psychosocial Expectancies (PROMIS Smoking Initiative) Patient Reported Outcome measure: Confidence sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Pro-Change Behavior Systems, Inc city: South Kingstown state: Rhode Island zip: 02879 country: United States lat: 41.44718 lon: -71.52494 hasResults: False
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<|newrecord|> nctId: NCT06292117 id: 230247 briefTitle: Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke acronym: ORCA-AIS overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-06 date: 2026-06 date: 2024-03-04 date: 2024-03-04 name: University of Virginia class: OTHER name: American Heart Association briefSummary: The goal of this observational study is to use a genetic test to help doctors prescribe the most effective medications after a patient has a stroke. One type of stroke is caused by a blood clot in brain vessels. After a patient has this kind of stroke, they are often given a combination of two blood thinners to prevent it from happening again. One of these blood thinners, called clopidogrel, is less effective in some people due to differences in their DNA. Clopidogrel needs to be activated by a specific enzyme in the body known as CYP2C19. This enzyme does not work as well if there are variations in the section of DNA that tells the body how to make CYP2C19. It can be predicted who has less CYP2C19 enzyme activity with a genetic test. If these patients are given a different blood thinner, it can reduce their risk of another stroke compared to if they are given clopidogrel.
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The main questions this study aims to answer are:
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* What are the best strategies to implement this genetic test in the hospital?
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* Does implementation of this genetic test change providers' decisions on which medication to prescribe after a participant has a stroke?
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Participants in this study will have a genetic test done onsite looking for variations in the section of DNA that tells the body how to make CYP2C19. This genetic test will only look for 11 known variations; the genome will not be sequenced. The investigators will alert the doctor of the patient's test results so they can prescribe the appropriate blood thinner. Through this, the investigators will learn the best practices for successful implementation of this genetic test. conditions: Ischemic Stroke conditions: CYP2C19 Polymorphism studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 350 type: ESTIMATED name: CYP2C19 Genotype measure: Percentage of patients discharged from University of Virginia (UVA) Health on dual antiplatelet therapy with a diagnosis of AIS/TIA meeting eligibility criteria upon presentation that are successfully genotyped measure: Average turnaround time of genotype result from time of collection of blood sample to time result is entered into the electronic health record measure: Number of CYP2C19 LOF carriers for whom a genotype-guided modification to DAPT is made measure: Number needed to genotype (NNG): number of patients who would need to undergo genotyping to have a recommended change in DAPT based on genotype measure: Stroke-free status via the Questionnaire to Verify Stroke-Free Status (QVSFS) of participants at 90 days in participants who received DAPT measure: Major adverse cardiovascular events at 90 days in participants who received DAPT measure: Correlation between P2Y12 reaction units (PRUs) measured via P2Y12 assay and CYP2C19 genotype in patients who received DAPT measure: Acceptability of deferred consent process in participants approached for full informed consent measure: Cost-effectiveness of CYP2C19-guided dual antiplatelet therapy after acute ischemic stroke sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
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<|newrecord|> nctId: NCT06292104 id: STU-2023-0589 id: 1R01HL166272-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/1R01HL166272-01A1 briefTitle: Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS) overallStatus: RECRUITING date: 2024-03-05 date: 2028-12 date: 2029-01 date: 2024-03-04 date: 2024-04-26 name: University of Texas Southwestern Medical Center class: OTHER name: National Heart, Lung, and Blood Institute (NHLBI) briefSummary: This is an observational study to deeply phenotype the disorder of POTS using multiple testing modalities. conditions: Postural Orthostatic Tachycardia Syndrome studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 350 type: ESTIMATED name: multimodal diagnostic testing measure: Phenotyping POTS measure: Natural history measure: Natural history sex: ALL minimumAge: 14 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: UT Southwestern Medical Center status: RECRUITING city: Dallas state: Texas zip: 75208 country: United States name: Steven Hopkins role: CONTACT phone: 214-648-9275 email: steve.hopkins@utsouthwestern.edu name: Steven Hopkins role: CONTACT phone: 2146489275 email: steve.hopkins@utsouthwestern.edu name: Steven Vernino, MD, PhD role: PRINCIPAL_INVESTIGATOR lat: 32.78306 lon: -96.80667 hasResults: False
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<|newrecord|> nctId: NCT06292091 id: Ur_ABD_PK briefTitle: A Study to Investigate the Effect of Urine Acid-base Disequilibrium on the Pharmacokinetics of Captopril overallStatus: COMPLETED date: 2024-02-28 date: 2024-03-27 date: 2024-04-01 date: 2024-03-04 date: 2024-04-17 name: Seoul National University Hospital class: OTHER briefSummary: The aim of this study is to evaluate the effect of urine acid-base disequilibrium on the pharmacokinetics of captopril in healthy male volunteers. conditions: Hypertension studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: OTHER masking: NONE count: 12 type: ACTUAL name: Captopril 12.5 Mg name: Sodium bicarbonate 4 G name: Torsemide 20 MG measure: AUClast of captopril measure: Cmax of captopril measure: AUCinf of captopril measure: Tmax of captopril measure: t1/2 of captopril measure: CL/F of captopril measure: Vd/F of captopril measure: fe of captopril measure: urine pH measure: Safety parameters sex: MALE minimumAge: 19 Years maximumAge: 50 Years stdAges: ADULT facility: Seoul National University Hospital city: Seoul zip: 03080 country: Korea, Republic of lat: 37.566 lon: 126.9784 hasResults: False
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<|newrecord|> nctId: NCT06292078 id: 1R01DA059401-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01DA059401-01 id: 1R01DA059401-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01DA059401-01 briefTitle: Preventing School Exclusion and Opioid Misuse: Effectiveness of the Inclusive Skill-building Learning Approach (ISLA) acronym: ISLA overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2028-08 date: 2028-08 date: 2024-03-04 date: 2024-03-04 name: University of Oregon class: OTHER name: National Institute on Drug Abuse (NIDA) briefSummary: This project will test the effectiveness of the Inclusive Skill-building Learning Approach (ISLA) in reducing the use of exclusionary discipline, improving teacher practice and student outcomes, and decreasing substance misuse using a randomized controlled trial in 60 middle schools across six states. conditions: Opioid Misuse studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 5076 type: ESTIMATED name: Instructional Skill-Building Learning Approach (ISLA) measure: Frequency and Duration of Use of Office Discipline Referrals, In-School Suspension, and Out-of-School Suspension measure: Engagement vs. Disaffection with Learning Student-report measure: Inclusive Teaching Practices measure: School Climate Survey- Student measure: School Climate- Teacher measure: Student-Teacher Relationships measure: Opioid and Other Substance Misuse measure: Student Internalizing Behaviors measure: Student Externalizing Behaviors measure: ISLA Acceptability measure: ISLA Implementation Fidelity sex: ALL minimumAge: 8 Years maximumAge: 15 Years stdAges: CHILD hasResults: False
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<|newrecord|> nctId: NCT06292065 id: Project ID 6171 briefTitle: Gastric Ultrasound To Assess Gastric Contents In Patients On Semaglutide Therapy acronym: GUST overallStatus: RECRUITING date: 2024-04-14 date: 2024-12-31 date: 2024-12-31 date: 2024-03-04 date: 2024-04-05 name: Nils Vlaeminck class: OTHER briefSummary: Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1-RA) such as semaglutide (Ozempic™, Rybelsus™, Wegovy™) were first introduced as a therapeutic agent for type 2 diabetes mellitus but they are being increasingly used to target weight loss in obesity.
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One of the mechanisms by which weight loss is achieved, is increased satiety and significantly delayed gastric emptying. Tachyphylaxis for this effect has been reported with chronic use of long acting GLP-1-RA (e.g. semaglutide) but this was based on the paracetamol absorption technique or 13C breath test. Recent clinical data suggests semaglutide use does increase perioperative gastric content.This creates uncertainty for anaesthetists who are, anecdotally, more frequently faced with patients who may or may not have full stomachs despite adhering to conventional fasting guidelines.
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To address this issue the American Society of Anesthesiologists (ASA) has recently released guidelines in which it advises to hold GLP-1-RA for one day (if administered daily) or one week (if administered weekly).
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However, these recommendations are based on sparse empirical evidence and they do not necessarily follow from the known pharmacokinetic properties of these drugs. Typically, GLP-1-RA are administered in increasing doses over several weeks until a therapeutic steady state is achieved. Meanwhile the elimination half-life of e.g. semaglutide is 7 days. This means that holding semaglutide for one day or even one week might not be enough to attenuate its therapeutic effect of delayed gastric emptying. On the other hand if semaglutide were to be held for e.g. 5 terminal half-lifes, this would mean an unpractical 5 weeks during which glycemic control may be worsened and after which semaglutide doses would have to be incrementally increased again. Besides, hyperglycaemia secondary to semaglutide cessation can also delay gastric emptying.
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Further confounding the assessment of these patients there can be 'background' delayed gastric emptying in diabetic patients and more pronounced delayed gastric emptying in patients recently started on GLP-1-RA. The presence of gastro-intestinal symptoms (nausea, vomiting, dyspepsia, abdominal distension) might offer clinical information regarding increased gastric residue in this population.
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Gastric ultrasound is a point-of-care clinical and research tool that has steadily gained popularity to assess gastric content in patients not compliant with fasting rules or with certain comorbidities. Clinical decisions can be made based on the visualised content (e.g. solids, fluids or nothing) or through calculation of gastric volume by measuring antral circumference. In this study the investigators will examine gastric contents in patients who are taking semaglutide and in patients who are not. The investigators will then evaluate whether there is a difference in the incidence of full stomachs and whether gastric ultrasound influenced the anaesthetic plan of the treating anaesthetist. conditions: Gastroparesis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: 45 patients on semaglutide therapy will be included together with 45 age, BMI and diabetes status matched controls. primaryPurpose: DIAGNOSTIC masking: NONE count: 90 type: ESTIMATED name: Point-of-care gastric ultrasound measure: Prevalence of full stomach measure: Frequency of changes to the anaesthetic plan measure: Calculated gastric content measure: Prevalence of solid gastric content measure: Association between fasting time for solids and 'full stomach' measure: Association between fasting time for liquids and 'full stomach' measure: Frequency of perioperative aspiration measure: Prevalence of gastric symptoms measure: Association between nausea and 'full stomach' measure: Association between vomiting and 'full stomach' measure: Association between dyspepsia and 'full stomach' measure: Association between abdominal distension and 'full stomach' measure: association between semaglutide dose and calculated gastric content measure: association between semaglutide dose and 'full stomach' measure: Association between frequency of semaglutide administration and calculated gastric content measure: Association between frequency of semaglutide administration and 'full stomach' measure: Association between duration of semaglutide therapy and calculated gastric content measure: Association between duration of semaglutide therapy at current dose and calculated gastric content measure: Association between duration of semaglutide therapy and 'full stomach' measure: Association between duration of semaglutide therapy at current dose and 'full stomach' measure: Association between duration of cessation of semaglutide and calculated gastric content measure: Association between duration of cessation of semaglutide and 'full stomach' measure: Association between preoperative blood glucose levels and calculated gastric content measure: Association between preoperative blood glucose levels and 'full stomach' measure: Association between HbA1c levels and calculated gastric content measure: Association between HbA1c levels and 'full stomach' measure: Association between time since onset of diabetes mellitus and calculated gastric content measure: Association between time since onset of diabetes mellitus and 'full stomach' sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Antwerp University Hospital status: RECRUITING city: Edegem state: Antwerp zip: 2650 country: Belgium name: Nils Vlaeminck role: CONTACT phone: 038215865 email: nils.vlaeminck@uza.be name: Vera Saldien role: CONTACT phone: 038214788 email: vera.saldien@uza.be lat: 51.15662 lon: 4.44504 hasResults: False
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<|newrecord|> nctId: NCT06292052 id: NSCLC-TDLN-001 briefTitle: Relation Between Tumor-draining Lymph Nodes Metastasis Pattern and Non-small Cell Lung Cancer Neoadjuvant Immunotherapy Effectiveness overallStatus: RECRUITING date: 2017-01-01 date: 2024-03-01 date: 2024-04-01 date: 2024-03-04 date: 2024-03-04 name: Sun Yat-sen University class: OTHER name: Jiangmen Central Hospital name: Henan Cancer Hospital briefSummary: The goal of this retrospective cohort analysis is to discover the impact of the involvement extent of tumor-draining lymph nodes (TDLNs) in patients who received neoadjuvant immunochemotherapy. The main question it aims to answer is the role of TDLN in the prediction of treatment effectiveness. Researches will compare tumor-draining lymph nodes metastasis (mTDLNs) group and non-draining lymph nodes metastasis (mNDLNs) group to see whether different metastatic patterns of mediastinal lymph nodes can indicate the treatment effectiveness. conditions: Lung Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 350 type: ESTIMATED name: Immunotherapy measure: Complete pathologic response measure: Major pathologic response measure: Complete pathologic response in lymph nodes sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sun Yat-sen University Cancer Center status: RECRUITING city: Guangzhou state: Guangdong zip: 510060 country: China name: Hao Long, MD role: CONTACT phone: +86-13802770989 email: longhao@sysucc.org.cn lat: 23.11667 lon: 113.25 hasResults: False
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<|newrecord|> nctId: NCT06292039 id: P0555788 id: 2KL2TR001870 type: NIH link: https://reporter.nih.gov/quickSearch/2KL2TR001870 briefTitle: Human-centered Injury Thrivorship Pathway for Survivors of Physical Trauma overallStatus: NOT_YET_RECRUITING date: 2025-07 date: 2026-04 date: 2026-06 date: 2024-03-04 date: 2024-03-06 name: University of California, San Francisco class: OTHER name: National Center for Advancing Translational Sciences (NCATS) briefSummary: The goal of this clinical trial is to pilot and evaluate a human-centered injury thrivorship pathway in injury survivors. The main question it aims to answer is:
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• Is the pathway appropriate, acceptable, and feasible to meet the medical and social needs of injury survivors?
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Injury survivors will be purposively sampled to enroll in the pathway and asked to participate in in-depth interviews and their use of pathway resources will be tracked. conditions: Injury Traumatic conditions: Survivorship conditions: Trauma Injury studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 25 type: ESTIMATED name: Human-Centered Injury Thrivorship Pathway measure: Early Implementation Outcomes - Acceptability, Appropriateness, Feasibility measure: Participant pathway resource utilization - type measure: Participant pathway resource utilization - frequency measure: Participant pathway resource utilization - duration measure: Participant pathway resource utilization - % utilized sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Zuckerberg San Francisco General Hospital city: San Francisco state: California zip: 94110 country: United States name: Marissa A Boeck, MD, MPH role: CONTACT phone: 415-502-4745 email: marissa.boeck@ucsf.edu lat: 37.77493 lon: -122.41942 hasResults: False
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<|newrecord|> nctId: NCT06292026 id: DFU/1 briefTitle: Efficacy of ProgenaMatrix™ in the Management of DFUs overallStatus: ACTIVE_NOT_RECRUITING date: 2022-03-14 date: 2026-03 date: 2026-09 date: 2024-03-04 date: 2024-03-04 name: ProgenaCare Global, LLC class: INDUSTRY briefSummary: This multicenter study will collect data to determine closure time for diabetic ulcers when following protocol parameters and treatment with ProgenaMatrix™. conditions: Diabetic Foot Ulcer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: The objective of this data collection is to look at outcomes and time points for ProgenaMatrix™ in the treatment of diabetic foot ulcers. Additionally, use the collected data to develop predictive wound closure models. There is a 1-week lead in period after initial debridement. If the wound is rapidly moving to closure after initial debridement and standard moist dressings, the withdrawal of these patients will prevent corruption of the true closure rate of ProgenaMatrix™. The objective of the treatment with ProgenaMatrix™ is to evaluate the closure rate in patients not responding to traditional moist therapy. primaryPurpose: TREATMENT masking: NONE count: 100 type: ACTUAL name: ProgenaMatrix Keratin graft name: standard of care measure: time to wound closure sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: United Wound Healing city: Puyallup state: Washington zip: 98371 country: United States lat: 47.18538 lon: -122.2929 hasResults: False
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<|newrecord|> nctId: NCT06292013 id: 18812 id: J3L-MC-EZEF type: OTHER domain: Eli Lilly and Company id: 2023-509190-23 type: EUDRACT_NUMBER briefTitle: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a) overallStatus: RECRUITING date: 2024-03-05 date: 2029-03 date: 2029-03 date: 2024-03-04 date: 2024-04-29 name: Eli Lilly and Company class: INDUSTRY briefSummary: The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovascular disease or are at risk of a heart attack or stroke. The study drug will be administered subcutaneously (SC) (under the skin). conditions: Atherosclerotic Cardiovascular Disease (ASCVD) conditions: Elevated Lp(a) studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 12500 type: ESTIMATED name: Lepodisiran Sodium name: Placebo measure: Time to First Occurrence of Any Component of the Major Adverse Cardiac Event (MACE)-4 Composite Endpoint measure: Change from Baseline in Lipoprotein(a) [Lp(a)] at Week 4 measure: Time to First Occurrence of Any of the Component of MACE-3 Composite Endpoint measure: Time to First Occurrence of Fatal or Non-Fatal Myocardial Infarction measure: Time to Cardiovascular Death measure: Time to Occurrence of All-Cause Death measure: Time to First Occurrence of Any Component of the MACE-4 Composite Endpoint (In the Population with Established ASCVD and CV Event, or Revascularization) measure: Time to First Occurrence of any Component of the MACE-4 Composite Endpoint (In the Population At Risk for First CV event) measure: Time to First Occurrence of any Component of the MACE-4 Composite Endpoint (In the Population with Lp(a) ≥ 200 nmol/L) measure: Time to First Occurrence of Any Component of MACE-3 + MALE Composite Endpoint measure: Time to First Occurrence of Any Component of Coronary MACE-3 Composite Endpoint sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Birmingham Clinical Research status: RECRUITING city: Birmingham state: Alabama zip: 35209 country: United States name: Nova Law role: PRINCIPAL_INVESTIGATOR lat: 33.52066 lon: -86.80249 facility: Alliance for Multispecialty Research, LLC status: RECRUITING city: Daphne state: Alabama zip: 36526 country: United States name: Michael T. Ledet role: PRINCIPAL_INVESTIGATOR lat: 30.60353 lon: -87.9036 facility: SEC Clinical Research status: RECRUITING city: Dothan state: Alabama zip: 36305 country: United States name: Andreas Muench role: PRINCIPAL_INVESTIGATOR lat: 31.22323 lon: -85.39049 facility: Alliance for Multispecialty Research, LLC status: RECRUITING city: Mobile state: Alabama zip: 36608 country: United States name: Harry E Studdard role: PRINCIPAL_INVESTIGATOR lat: 30.69436 lon: -88.04305 facility: Mobile Heart Specialists status: RECRUITING city: Mobile state: Alabama zip: 36608 country: United States name: Christopher S. Brown role: PRINCIPAL_INVESTIGATOR lat: 30.69436 lon: -88.04305 facility: Alaska Heart and Vascular Institute status: NOT_YET_RECRUITING city: Anchorage state: Alaska zip: 99508 country: United States name: Jacob Kelly role: PRINCIPAL_INVESTIGATOR lat: 61.21806 lon: -149.90028 facility: Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC status: RECRUITING city: Gilbert state: Arizona zip: 85296 country: United States name: Sunildat Maheshwari role: PRINCIPAL_INVESTIGATOR lat: 33.35283 lon: -111.78903 facility: Mercy Gilbert Medical Center status: NOT_YET_RECRUITING city: Gilbert state: Arizona zip: 85297 country: United States name: Nabil Dib role: PRINCIPAL_INVESTIGATOR lat: 33.35283 lon: -111.78903 facility: AMZERN Clinical Trial Organization status: RECRUITING city: Peoria state: Arizona zip: 85381 country: United States name: Kishlay Anand role: PRINCIPAL_INVESTIGATOR lat: 33.5806 lon: -112.23738 facility: Elite Clinical Studies status: RECRUITING city: Phoenix state: Arizona zip: 85018 country: United States name: Joseph Lillo, DO role: PRINCIPAL_INVESTIGATOR lat: 33.44838 lon: -112.07404 facility: Helios Clinical Research - Phoenix status: RECRUITING city: Phoenix state: Arizona zip: 85028 country: United States name: David Francyk role: PRINCIPAL_INVESTIGATOR lat: 33.44838 lon: -112.07404 facility: Absolute Clinical Research status: RECRUITING city: Phoenix state: Arizona zip: 85051 country: United States name: James Beach role: PRINCIPAL_INVESTIGATOR lat: 33.44838 lon: -112.07404 facility: Clinical Research Institute of Arizona (CRI) - Sun City West status: RECRUITING city: Sun City West state: Arizona zip: 85375 country: United States name: Jalal Abbas role: PRINCIPAL_INVESTIGATOR lat: 33.66198 lon: -112.34127 facility: Synexus Clinical Research US, Inc./Orange Grove Family Practice status: RECRUITING city: Tucson state: Arizona zip: 85741 country: United States name: Kevin Lee Pounds role: PRINCIPAL_INVESTIGATOR lat: 32.22174 lon: -110.92648 facility: Eclipse Clinical Research status: NOT_YET_RECRUITING city: Tucson state: Arizona zip: 85745 country: United States name: Eve C Shapiro role: PRINCIPAL_INVESTIGATOR lat: 32.22174 lon: -110.92648 facility: Cardiology and Medicine Clinic status: NOT_YET_RECRUITING city: Little Rock state: Arkansas zip: 72204 country: United States name: Joe Louis Hargrove role: PRINCIPAL_INVESTIGATOR lat: 34.74648 lon: -92.28959 facility: Westside Medical Associates of Los Angeles status: NOT_YET_RECRUITING city: Beverly Hills state: California zip: 90211 country: United States name: Norman ELLIOTT Lepor role: PRINCIPAL_INVESTIGATOR lat: 34.07362 lon: -118.40036 facility: Valley Clinical Trials, Inc. status: RECRUITING city: Covina state: California zip: 91723 country: United States name: Fahed G Bitar role: PRINCIPAL_INVESTIGATOR lat: 34.09001 lon: -117.89034 facility: Neighborhood Healthcare Institute of Health status: RECRUITING city: Escondido state: California zip: 92025 country: United States name: James H Schultz role: PRINCIPAL_INVESTIGATOR lat: 33.11921 lon: -117.08642 facility: HB Clinical Trials - Fountain Valley status: RECRUITING city: Fountain Valley state: California zip: 92708 country: United States name: Vinod Malhotra role: PRINCIPAL_INVESTIGATOR lat: 33.70918 lon: -117.95367 facility: Care Access Research - Huntington Beach status: RECRUITING city: Huntington Beach state: California zip: 92648 country: United States name: Christine Thai role: PRINCIPAL_INVESTIGATOR lat: 33.6603 lon: -117.99923 facility: 310 Clinical Research status: RECRUITING city: Inglewood state: California zip: 90301 country: United States name: Soheil Hekmat role: PRINCIPAL_INVESTIGATOR lat: 33.96168 lon: -118.35313 facility: UCSD - Altman Clinical and Translational Research Institute (ACTRI) status: NOT_YET_RECRUITING city: La Jolla state: California zip: 92037-7410 country: United States name: Michael Wilkinson role: PRINCIPAL_INVESTIGATOR lat: 32.84727 lon: -117.2742 facility: Scripps Whittier Diabetes Institute status: NOT_YET_RECRUITING city: La Jolla state: California zip: 92037 country: United States name: James David McCallum role: PRINCIPAL_INVESTIGATOR lat: 32.84727 lon: -117.2742 facility: First Valley Medical Group status: NOT_YET_RECRUITING city: Lancaster state: California zip: 93534 country: United States name: Kanagaratnam Sivalingam role: PRINCIPAL_INVESTIGATOR lat: 34.69804 lon: -118.13674 facility: MemorialCare Health System - Long Beach Medical Center status: NOT_YET_RECRUITING city: Long Beach state: California zip: 90806 country: United States name: Mark Lee role: PRINCIPAL_INVESTIGATOR lat: 33.76696 lon: -118.18923 facility: Ark Clinical Research status: RECRUITING city: Long Beach state: California zip: 90815 country: United States name: Apinya Vutikullird role: PRINCIPAL_INVESTIGATOR lat: 33.76696 lon: -118.18923 facility: Keck School of Medicine of USC status: NOT_YET_RECRUITING city: Los Angeles state: California zip: 90033 country: United States name: Parveen Garg role: PRINCIPAL_INVESTIGATOR lat: 34.05223 lon: -118.24368 facility: Cardiovascular Research Foundation of Southern California status: NOT_YET_RECRUITING city: Los Angeles state: California zip: 90210 country: United States name: Ronald P Karlsberg role: PRINCIPAL_INVESTIGATOR lat: 34.05223 lon: -118.24368 facility: Desert Oasis Healthcare Medical Group status: RECRUITING city: Palm Springs state: California zip: 92262 country: United States name: Michael Jardula role: PRINCIPAL_INVESTIGATOR lat: 33.8303 lon: -116.54529 facility: Artemis Institute for Clinical Research status: NOT_YET_RECRUITING city: San Diego state: California zip: 92103 country: United States name: Stacey Layle role: PRINCIPAL_INVESTIGATOR lat: 32.71533 lon: -117.15726 facility: Care Access - Santa Clarita status: RECRUITING city: Santa Clarita state: California zip: 91321 country: United States name: Sina Tebi role: PRINCIPAL_INVESTIGATOR lat: 34.39166 lon: -118.54259 facility: Millennium Clinical Trials status: RECRUITING city: Simi Valley state: California zip: 93065 country: United States name: Edward Portnoy role: PRINCIPAL_INVESTIGATOR lat: 34.26945 lon: -118.78148 facility: Stanford University Medical Center status: NOT_YET_RECRUITING city: Stanford state: California zip: 94305 country: United States name: Abha Khandelwal role: PRINCIPAL_INVESTIGATOR lat: 37.42411 lon: -122.16608 facility: Olive View-UCLA Medical Center status: NOT_YET_RECRUITING city: Sylmar state: California zip: 91342 country: United States name: Jonathan Soverow role: PRINCIPAL_INVESTIGATOR lat: 34.30778 lon: -118.44925 facility: Care Access - Thousand Oaks status: RECRUITING city: Thousand Oaks state: California zip: 91360 country: United States name: Irving Loh role: PRINCIPAL_INVESTIGATOR lat: 34.17056 lon: -118.83759 facility: Med Partners, Inc. dba Premiere Medical Center of Burbank, Inc. status: RECRUITING city: Toluca Lake state: California zip: 91602 country: United States name: Michael Marsh role: PRINCIPAL_INVESTIGATOR lat: 34.15262 lon: -118.35731 facility: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center status: NOT_YET_RECRUITING city: Torrance state: California zip: 90502 country: United States name: William French role: PRINCIPAL_INVESTIGATOR lat: 33.83585 lon: -118.34063 facility: UCLA South Bay Endocrinology status: NOT_YET_RECRUITING city: Torrance state: California zip: 90505 country: United States name: Dianne Cheung role: PRINCIPAL_INVESTIGATOR lat: 33.83585 lon: -118.34063 facility: InvivoCure status: RECRUITING city: Van Nuys state: California zip: 91405 country: United States name: Rodney Samaan role: PRINCIPAL_INVESTIGATOR lat: 34.18667 lon: -118.44897 facility: Synexus Clinical Research US - Vista status: RECRUITING city: Vista state: California zip: 92083 country: United States name: Isabel J. Pereira role: PRINCIPAL_INVESTIGATOR lat: 33.20004 lon: -117.24254 facility: Interventional Cardiology Medical Group status: RECRUITING city: West Hills state: California zip: 91307 country: United States name: Farhad Rafii role: PRINCIPAL_INVESTIGATOR lat: 34.19731 lon: -118.64398 facility: University of Colorado Anschutz Medical Campus status: RECRUITING city: Aurora state: Colorado zip: 80045 country: United States name: Neda Rasouli role: PRINCIPAL_INVESTIGATOR lat: 39.72943 lon: -104.83192 facility: Bridgeport Hospital status: RECRUITING city: Bridgeport state: Connecticut zip: 06610 country: United States name: Adam Schussheim role: PRINCIPAL_INVESTIGATOR lat: 41.16704 lon: -73.20483 facility: Hartford Hospital (HH) status: NOT_YET_RECRUITING city: Hartford state: Connecticut zip: 06102 country: United States name: Antonio Fernandez role: PRINCIPAL_INVESTIGATOR lat: 41.76371 lon: -72.68509 facility: Cardiology Associates of Fairfield County, P.C. status: RECRUITING city: Stamford state: Connecticut zip: 06905 country: United States name: Thomas Nero role: PRINCIPAL_INVESTIGATOR lat: 41.05343 lon: -73.53873 facility: Chase Medical Research, LLC status: RECRUITING city: Waterbury state: Connecticut zip: 06708 country: United States name: Joseph Soufer role: PRINCIPAL_INVESTIGATOR lat: 41.55815 lon: -73.0515 facility: MedStar Washington Hospital Center status: NOT_YET_RECRUITING city: Washington state: District of Columbia zip: 20010 country: United States name: Ron Waksman role: PRINCIPAL_INVESTIGATOR lat: 38.89511 lon: -77.03637 facility: Excel Medical Clinical Trials status: RECRUITING city: Boca Raton state: Florida zip: 33434 country: United States name: DAVID FUNT role: PRINCIPAL_INVESTIGATOR lat: 26.3669 lon: -80.13033 facility: Clearwater Cardiovascular & Interventional Consultants M.D., P.A. status: NOT_YET_RECRUITING city: Clearwater state: Florida zip: 33756 country: United States name: Douglas J Spriggs role: PRINCIPAL_INVESTIGATOR lat: 27.96585 lon: -82.8001 facility: Clinical Research of West Florida, Inc. (Clearwater) status: NOT_YET_RECRUITING city: Clearwater state: Florida zip: 33765 country: United States name: Leonard Jay Dunn role: PRINCIPAL_INVESTIGATOR lat: 27.96585 lon: -82.8001 facility: Elite Cardiac Research Center status: NOT_YET_RECRUITING city: Hialeah state: Florida zip: 33013 country: United States name: Manuel Bouza role: PRINCIPAL_INVESTIGATOR lat: 25.8576 lon: -80.27811 facility: Westside Center for Clinical Research status: RECRUITING city: Jacksonville state: Florida zip: 32205 country: United States name: Albert Lopez role: PRINCIPAL_INVESTIGATOR lat: 30.33218 lon: -81.65565 facility: Encore Research Group- Jacksonville Center for Clinical Research status: RECRUITING city: Jacksonville state: Florida zip: 32216 country: United States name: Michael Koren role: PRINCIPAL_INVESTIGATOR lat: 30.33218 lon: -81.65565 facility: Clearwater Cardiovascular & Interventional Consultants M.D., P.A. status: NOT_YET_RECRUITING city: Largo state: Florida zip: 33777 country: United States name: Syed Masood Gilani role: PRINCIPAL_INVESTIGATOR lat: 27.90979 lon: -82.78842 facility: K2 Medical Research - Maitland status: RECRUITING city: Maitland state: Florida zip: 32751 country: United States name: Neel Patel role: PRINCIPAL_INVESTIGATOR lat: 28.62778 lon: -81.36312 facility: South Florida Clinical Research Institute status: RECRUITING city: Margate state: Florida zip: 33063 country: United States name: Juan Loy role: PRINCIPAL_INVESTIGATOR lat: 26.24453 lon: -80.20644 facility: Inpatient Research Clinic status: RECRUITING city: Miami Lakes state: Florida zip: 33014 country: United States name: Alexis Gutierrez role: PRINCIPAL_INVESTIGATOR lat: 25.90871 lon: -80.30866 facility: Suncoast Research Group status: RECRUITING city: Miami state: Florida zip: 33135 country: United States name: Mark Kutner role: PRINCIPAL_INVESTIGATOR lat: 25.77427 lon: -80.19366 facility: Advanced Research for Health Improvement, LLC status: RECRUITING city: Naples state: Florida zip: 34102 country: United States name: Julian J. Javier role: PRINCIPAL_INVESTIGATOR lat: 26.14234 lon: -81.79596 facility: Renstar Medical Research status: RECRUITING city: Ocala state: Florida zip: 34470 country: United States name: David Lucius Oliver role: PRINCIPAL_INVESTIGATOR lat: 29.1872 lon: -82.14009 facility: Elixia Central Florida status: RECRUITING city: Orlando state: Florida zip: 32806 country: United States name: Arvind Madan role: PRINCIPAL_INVESTIGATOR lat: 28.53834 lon: -81.37924 facility: Florida Institute For Clinical Research, LLC status: RECRUITING city: Orlando state: Florida zip: 32825 country: United States name: Humberto Cruz role: PRINCIPAL_INVESTIGATOR lat: 28.53834 lon: -81.37924 facility: Innovative Research Institute - Port Charlotte status: RECRUITING city: Port Charlotte state: Florida zip: 33952 country: United States name: Joseph Ravid role: PRINCIPAL_INVESTIGATOR lat: 26.97617 lon: -82.09064 facility: Peace River Cardiovascular Center status: RECRUITING city: Port Charlotte state: Florida zip: 33952 country: United States name: David Hotchkiss role: PRINCIPAL_INVESTIGATOR lat: 26.97617 lon: -82.09064 facility: Progressive Medical Research status: NOT_YET_RECRUITING city: Port Orange state: Florida zip: 32127 country: United States name: Richard Mohammed role: PRINCIPAL_INVESTIGATOR lat: 29.13832 lon: -80.99561 facility: Clearwater Cardiovascular & Interventional Consultants M.D., P.A. status: NOT_YET_RECRUITING city: Safety Harbor state: Florida zip: 34695 country: United States name: Kenneth C. Sabatino role: PRINCIPAL_INVESTIGATOR lat: 27.99085 lon: -82.69316 facility: Clinical Research of West Florida status: NOT_YET_RECRUITING city: Tampa state: Florida zip: 33606 country: United States name: Lon D. 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L. 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Laura Maffei- Investigacion Clinica Aplicada status: RECRUITING city: Ciudad Autonoma de Buenos Aires state: Ciudad Autónoma De Buenos Aires zip: C1425AGC country: Argentina name: Emilio Daniel Alaguibe role: PRINCIPAL_INVESTIGATOR lat: -34.61315 lon: -58.37723 facility: Clínica Privada del Prado SRL status: NOT_YET_RECRUITING city: Alberdi state: Córdoba zip: 5000 country: Argentina name: Maria Alejandra Gutierrez role: PRINCIPAL_INVESTIGATOR lat: -32.88987 lon: -60.69058 facility: Instituto Médico Río Cuarto status: NOT_YET_RECRUITING city: Río Cuarto state: Córdoba zip: X5800AEV country: Argentina name: Osvaldo Magri role: PRINCIPAL_INVESTIGATOR lat: -33.13067 lon: -64.34992 facility: Centro Privado de Medicina Respiratoria status: RECRUITING city: Paraná state: Entre Ríos zip: 3100 country: Argentina name: Luis Darío Larrateguy role: PRINCIPAL_INVESTIGATOR lat: -31.73197 lon: -60.5238 facility: CIPADI - Centro Integral de Prevencion y Atencion en Diabetes status: RECRUITING city: 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Buenos Aires Macula S.A status: NOT_YET_RECRUITING city: Buenos Aires zip: 1061 country: Argentina name: Augusto Lavalle Cobo role: PRINCIPAL_INVESTIGATOR lat: -34.61315 lon: -58.37723 facility: Instituto Médico Especializado (IME) status: NOT_YET_RECRUITING city: Buenos Aires zip: 1405 country: Argentina name: Gabriela Laura Rossi role: PRINCIPAL_INVESTIGATOR lat: -34.61315 lon: -58.37723 facility: Consultorio Medico Investigador Principal Dr Besada status: NOT_YET_RECRUITING city: Buenos Aires zip: 1426 country: Argentina name: Diego Alejandro Besada role: PRINCIPAL_INVESTIGATOR lat: -34.61315 lon: -58.37723 facility: Instituto Cardiovascular de Buenos Aires status: NOT_YET_RECRUITING city: Buenos Aires zip: 1428 country: Argentina name: Fernando Osvaldo Botto role: PRINCIPAL_INVESTIGATOR lat: -34.61315 lon: -58.37723 facility: CEMEDIC status: RECRUITING city: Buenos Aires zip: C1407GTN country: Argentina name: Claudio Majul role: PRINCIPAL_INVESTIGATOR lat: -34.61315 lon: -58.37723 facility: Fundación Respirar status: RECRUITING city: Buenos Aires zip: C1426ABP country: Argentina name: Marina Uhrig role: PRINCIPAL_INVESTIGATOR lat: -34.61315 lon: -58.37723 facility: Instituto de Cardiología "Juana F. 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lat: -33.90011 lon: 150.93328 facility: The AIM Centre / Hunter Diabetes Centre status: RECRUITING city: Merewether state: New South Wales zip: 2291 country: Australia name: Claire Morbey role: PRINCIPAL_INVESTIGATOR lat: -32.94801 lon: 151.74325 facility: AusTrials - St. Leonards status: RECRUITING city: Sydney state: New South Wales zip: 2065 country: Australia name: (Alexander) Munro Neville role: PRINCIPAL_INVESTIGATOR lat: -33.86785 lon: 151.20732 facility: Royal Brisbane and Women's Hospital status: NOT_YET_RECRUITING city: Brisbane state: Queensland zip: 4029 country: Australia name: CHRISTOPHER HAMMETT role: PRINCIPAL_INVESTIGATOR lat: -27.46794 lon: 153.02809 facility: Core Research Group status: RECRUITING city: Brisbane state: Queensland zip: 4064 country: Australia name: David Martin Colquhoun role: PRINCIPAL_INVESTIGATOR lat: -27.46794 lon: 153.02809 facility: Heart of Australia status: RECRUITING city: Brisbane state: Queensland zip: 4068 country: Australia name: Rolf 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facility: Care Access - Cape Breton status: RECRUITING city: Sydney state: Nova Scotia zip: B1M 0A1 country: Canada name: Paul MacDonald role: PRINCIPAL_INVESTIGATOR lat: 46.13511 lon: -60.1831 facility: Cardio Health Clinical Trial - Brampton status: RECRUITING city: Brampton state: Ontario zip: L6Y 6H4 country: Canada name: Gary Maur role: PRINCIPAL_INVESTIGATOR lat: 43.68341 lon: -79.76633 facility: Hamilton Medical Research Group status: RECRUITING city: Hamilton state: Ontario zip: L8M 1K7 country: Canada name: Richard Tytus role: PRINCIPAL_INVESTIGATOR lat: 43.25011 lon: -79.84963 facility: Cardio Health Clinical Trial - London status: RECRUITING city: London state: Ontario zip: N6H 5L4 country: Canada name: Zahid Sardar role: PRINCIPAL_INVESTIGATOR lat: 42.98339 lon: -81.23304 facility: North York Diagnostic and Cardiac Centre status: RECRUITING city: North York state: Ontario zip: M6B 3H7 country: Canada name: Subodh Verma role: PRINCIPAL_INVESTIGATOR lat: 43.76681 lon: -79.4163 facility: Oakville Cardiovascular Research LP status: RECRUITING city: Oakville state: Ontario zip: L6K 3W7 country: Canada name: Sean Jedrzkiewicz role: PRINCIPAL_INVESTIGATOR lat: 43.45011 lon: -79.68292 facility: Cardio Health Clinical Trial - St. Thomas status: RECRUITING city: St. Thomas state: Ontario zip: N5R 2R4 country: Canada name: Zahid Sardar role: PRINCIPAL_INVESTIGATOR lat: 42.77361 lon: -81.18038 facility: Corcare status: RECRUITING city: Toronto state: Ontario zip: M1B 5N1 country: Canada name: Paul Galiwango role: PRINCIPAL_INVESTIGATOR lat: 43.70011 lon: -79.4163 facility: Diabetes Heart Research Centre status: RECRUITING city: Toronto state: Ontario zip: M6G 1M2 country: Canada name: Luis Noronha role: PRINCIPAL_INVESTIGATOR lat: 43.70011 lon: -79.4163 facility: Ecogene-21 status: RECRUITING city: Chicoutimi state: Quebec zip: G7H 7K9 country: Canada name: Daniel Gaudet role: PRINCIPAL_INVESTIGATOR lat: 48.41963 lon: -71.06369 facility: Viacar Recherche Clinique status: RECRUITING city: Greenfield Park state: Quebec zip: J4V 2G8 country: Canada name: Raja RECHERCHES Chehayeb role: PRINCIPAL_INVESTIGATOR lat: 45.48649 lon: -73.46223 facility: Clinique des Maladies Lipidiques de Québec status: RECRUITING city: Québec state: Quebec zip: G1V 4W2 country: Canada name: Jean Bergeron role: PRINCIPAL_INVESTIGATOR lat: 46.81228 lon: -71.21454 facility: Diex Recherche Joliette status: RECRUITING city: Saint-Charles-Borromée state: Quebec zip: J6E 2B4 country: Canada name: Laurence Laplante role: PRINCIPAL_INVESTIGATOR lat: 46.05007 lon: -73.46586 facility: Unité de Recherche Clinique du CISSS des Laurentides status: NOT_YET_RECRUITING city: St-Jerome state: Quebec zip: J7Z 2V4 country: Canada name: Yves Pesant role: PRINCIPAL_INVESTIGATOR lat: 45.78036 lon: -74.00365 facility: Centre de Medecine Metabolique de Lanaudiere (CMML) status: RECRUITING city: Terrebonne state: Quebec zip: J6X 4P7 country: Canada name: Yves Robitaille role: PRINCIPAL_INVESTIGATOR lat: 45.70004 lon: -73.64732 facility: Diex Recherche Trois-Rivieres status: RECRUITING city: Trois-Rivieres state: Quebec zip: G9A 4P3 country: Canada name: Ying Tung Sia role: PRINCIPAL_INVESTIGATOR lat: 46.34515 lon: -72.5477 facility: The Second People's Hospital of Hefei status: NOT_YET_RECRUITING city: Hefei state: Anhui zip: 230011 country: China name: Jun Ye role: PRINCIPAL_INVESTIGATOR lat: 31.86389 lon: 117.28083 facility: Anhui Provincil Hospital South District status: NOT_YET_RECRUITING city: Hefei state: Anhui zip: 230036 country: China name: Likun Ma role: PRINCIPAL_INVESTIGATOR lat: 31.86389 lon: 117.28083 facility: Wannan Medical College Yijishan Hospital status: NOT_YET_RECRUITING city: Wuhu state: Anhui zip: 241001 country: China name: Yueyun Chen role: PRINCIPAL_INVESTIGATOR lat: 31.33728 lon: 118.37351 facility: Beijing ChaoYang Hospital status: NOT_YET_RECRUITING city: Beijing state: Beijing zip: 100020 country: China name: Mulei Chen role: PRINCIPAL_INVESTIGATOR lat: 39.9075 lon: 116.39723 facility: Beijing Friendship Hospital status: NOT_YET_RECRUITING city: Beijing state: Beijing zip: 100050 country: China name: Mingxia Yuan role: PRINCIPAL_INVESTIGATOR lat: 39.9075 lon: 116.39723 facility: Peking University Third Hospital status: NOT_YET_RECRUITING city: Beijing state: Beijing zip: 100091 country: China name: Ming Cui role: PRINCIPAL_INVESTIGATOR lat: 39.9075 lon: 116.39723 facility: 2nd Affiliated Hospital Chongqing Medical Universi status: NOT_YET_RECRUITING city: Chongqing state: Chongqing zip: 400000 country: China name: ZHIYU LING role: PRINCIPAL_INVESTIGATOR lat: 29.56278 lon: 106.55278 facility: Chongqing Three Gorges Central Hospital status: NOT_YET_RECRUITING city: Wanzhou state: Chongqing zip: 404199 country: China name: Huaming Mou role: PRINCIPAL_INVESTIGATOR facility: Xiamen Cardiovascular Hospital status: NOT_YET_RECRUITING city: Xiamen state: Fujian zip: 361006 country: China name: Cuilian Dai role: PRINCIPAL_INVESTIGATOR lat: 24.47979 lon: 118.08187 facility: The First Hospital of Lanzhou University status: NOT_YET_RECRUITING city: Lanzhou state: Gansu zip: 730000 country: China name: Zheng Zhang role: PRINCIPAL_INVESTIGATOR lat: 36.05701 lon: 103.83987 facility: Lanzhou university second hospital status: NOT_YET_RECRUITING city: Lanzhou state: Gansu zip: 730030 country: China name: Xiaowei Zhang role: PRINCIPAL_INVESTIGATOR lat: 36.05701 lon: 103.83987 facility: Shunde Hospital of Southern Medical Univesity status: NOT_YET_RECRUITING city: Foshan state: Guangdong zip: 528399 country: China name: Yuli Huang role: PRINCIPAL_INVESTIGATOR lat: 23.02677 lon: 113.13148 facility: Guangdong Provincial People's Hospital status: NOT_YET_RECRUITING city: Guangzhou state: Guangdong zip: 510000 country: China name: Jiyan Chen role: PRINCIPAL_INVESTIGATOR lat: 23.11667 lon: 113.25 facility: Guangzhou First People's Hospital status: NOT_YET_RECRUITING city: Guangzhou state: Guangdong zip: 510180 country: China name: Jian Liu role: PRINCIPAL_INVESTIGATOR lat: 23.11667 lon: 113.25 facility: The First Affiliated Hospital, Sun Yat-sen University status: NOT_YET_RECRUITING city: Guangzhou state: Guangdong country: China name: Yugang Dong role: PRINCIPAL_INVESTIGATOR lat: 23.11667 lon: 113.25 facility: Huizhou Municipal Central Hospital status: NOT_YET_RECRUITING city: Huizhou state: Guangdong zip: 516001 country: China name: Xiongwei XIE role: PRINCIPAL_INVESTIGATOR lat: 23.11147 lon: 114.41523 facility: Shenzhen Sun Yat-sen Cardiovascular Hospital status: NOT_YET_RECRUITING city: Shenzhen state: Guangdong zip: 518057 country: China name: Xin Zheng role: PRINCIPAL_INVESTIGATOR lat: 22.54554 lon: 114.0683 facility: Guangxi People's Hospital status: NOT_YET_RECRUITING city: Nanning state: Guangxi zip: 530021 country: China name: Qingwei Ji role: PRINCIPAL_INVESTIGATOR lat: 22.81667 lon: 108.31667 facility: The First Hospital of Harbin Medical University status: NOT_YET_RECRUITING city: Harbin state: Heilongjiang zip: 150001 country: China name: Yue Li role: PRINCIPAL_INVESTIGATOR lat: 45.75 lon: 126.65 facility: The Fourth Hospital of Harbin Medical University status: NOT_YET_RECRUITING city: Harbin state: Heilongjiang zip: 150001 country: China name: ZhiFeng Cheng role: PRINCIPAL_INVESTIGATOR lat: 45.75 lon: 126.65 facility: The First Affiliated Hospital of Henan University of Science &Technology status: NOT_YET_RECRUITING city: Luoyang state: Henan zip: 471003 country: China name: Hongwei Jiang role: PRINCIPAL_INVESTIGATOR lat: 34.68361 lon: 112.45361 facility: The First Affiliated Hospital of Henan University of Science &Technology status: NOT_YET_RECRUITING city: Luoyang state: Henan zip: 471003 country: China name: Zhijuan Li role: PRINCIPAL_INVESTIGATOR lat: 34.68361 lon: 112.45361 facility: The First Affiliated Hospital of Nanyang Medical College status: NOT_YET_RECRUITING city: Nanyang state: Henan zip: 473007 country: China name: Dexue Liu role: PRINCIPAL_INVESTIGATOR lat: 32.99472 lon: 112.53278 facility: The First Affiliated Hospital of Nanyang Medical College status: NOT_YET_RECRUITING city: Nanyang state: Henan country: China name: Jie Li role: PRINCIPAL_INVESTIGATOR lat: 32.99472 lon: 112.53278 facility: The Second Affiliated Hospital of Zhengzhou University status: NOT_YET_RECRUITING city: Zhengzhou state: Henan zip: 450014 country: China name: Qingju Li role: PRINCIPAL_INVESTIGATOR lat: 34.75778 lon: 113.64861 facility: Jingzhou Central Hospital status: NOT_YET_RECRUITING city: Jingzhou state: Hubei zip: 434020 country: China name: Keping Yang role: PRINCIPAL_INVESTIGATOR lat: 30.35028 lon: 112.19028 facility: Wuhan University Medical College - Hubei Zhongshan Hospital status: NOT_YET_RECRUITING city: Wuhan state: Hubei zip: 430000 country: China name: Jingyi Zhang role: PRINCIPAL_INVESTIGATOR lat: 30.58333 lon: 114.26667 facility: Wuhan Asia Heart Hospital status: NOT_YET_RECRUITING city: Wuhan state: Hubei zip: 430022 country: China name: Hua Yan role: PRINCIPAL_INVESTIGATOR lat: 30.58333 lon: 114.26667 facility: Renmin Hospital of Wuhan University status: NOT_YET_RECRUITING city: Wuhan state: Hubei zip: 430060 country: China name: Xuejun Jiang role: PRINCIPAL_INVESTIGATOR lat: 30.58333 lon: 114.26667 facility: Changde First People's Hospital status: NOT_YET_RECRUITING city: Changde state: Hunan zip: 415000 country: China name: Liangqing GE role: PRINCIPAL_INVESTIGATOR lat: 29.04638 lon: 111.6783 facility: The Third Xiangya Hospital of Central South University status: NOT_YET_RECRUITING city: Changsha state: Hunan zip: 410013 country: China name: Weihong Jiang role: PRINCIPAL_INVESTIGATOR lat: 28.19874 lon: 112.97087 facility: The First People's Hospital of Yueyang status: NOT_YET_RECRUITING city: Yueyang state: Hunan zip: 414000 country: China name: Gang Pan role: PRINCIPAL_INVESTIGATOR lat: 29.37455 lon: 113.09481 facility: Chifeng Hospital status: NOT_YET_RECRUITING city: Chifeng state: Inner Mongolia zip: 024099 country: China name: XIANDONG SUN role: PRINCIPAL_INVESTIGATOR lat: 42.26833 lon: 118.96361 facility: Inner Mongolia People's Hospital status: NOT_YET_RECRUITING city: Hohhot state: Inner Mongolia zip: 010017 country: China name: Liping He role: PRINCIPAL_INVESTIGATOR lat: 40.81056 lon: 111.65222 facility: Changzhou Second People's Hospital status: NOT_YET_RECRUITING city: Changzhou state: Jiangsu zip: 213000 country: China name: Yuan Ji role: PRINCIPAL_INVESTIGATOR lat: 31.77359 lon: 119.95401 facility: Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School status: NOT_YET_RECRUITING city: Nanjing state: Jiangsu zip: 210000 country: China name: Biao Xu role: PRINCIPAL_INVESTIGATOR lat: 32.06167 lon: 118.77778 facility: Zhongda Hospital Southeast University status: NOT_YET_RECRUITING city: Nanjing state: Jiangsu zip: 210009 country: China name: Genshan Ma role: PRINCIPAL_INVESTIGATOR lat: 32.06167 lon: 118.77778 facility: The Second Affiliated Hospital of Nanjing Medical University status: NOT_YET_RECRUITING city: Nanjing state: Jiangsu zip: 210011 country: China name: Yibing Lu role: PRINCIPAL_INVESTIGATOR lat: 32.06167 lon: 118.77778 facility: The Second Affiliated Hospital of Nanjing Medical University status: NOT_YET_RECRUITING city: Nanjing state: Jiangsu zip: 210011 country: China name: Mingzhi Long role: PRINCIPAL_INVESTIGATOR lat: 32.06167 lon: 118.77778 facility: Jiangsu Province Hospital status: NOT_YET_RECRUITING city: Nanjing state: Jiangsu zip: 210029 country: China name: Dianfu Li role: PRINCIPAL_INVESTIGATOR lat: 32.06167 lon: 118.77778 facility: Wuxi People's Hospital status: NOT_YET_RECRUITING city: Wuxi state: Jiangsu zip: 214023 country: China name: Ruxing Wang role: PRINCIPAL_INVESTIGATOR lat: 31.56887 lon: 120.28857 facility: The Affiliated Hospital of Xuzhou Medical College status: NOT_YET_RECRUITING city: Xuzhou state: Jiangsu zip: 221006 country: China name: Hong Zhu role: PRINCIPAL_INVESTIGATOR lat: 34.18045 lon: 117.15707 facility: The Second Affiliated Hospital of Nanchang University status: NOT_YET_RECRUITING city: Nanchang state: Jiangxi zip: 330006 country: China name: Yanqing Wu role: PRINCIPAL_INVESTIGATOR lat: 28.68396 lon: 115.85306 facility: The Third Hospital of Nanchang status: NOT_YET_RECRUITING city: Nanchang state: Jiangxi zip: 330009 country: China name: Zhaohui Pei role: PRINCIPAL_INVESTIGATOR lat: 28.68396 lon: 115.85306 facility: The First Hospital of Jilin University status: NOT_YET_RECRUITING city: Changchun state: Jilin zip: 100012 country: China name: Qian Tong role: PRINCIPAL_INVESTIGATOR lat: 43.88 lon: 125.32278 facility: China-Japan Union Hospital status: NOT_YET_RECRUITING city: Changchun state: Jilin zip: 130033 country: China name: Yuquan He role: PRINCIPAL_INVESTIGATOR lat: 43.88 lon: 125.32278 facility: Siping Central People's Hospital status: NOT_YET_RECRUITING city: Siping state: Jilin zip: 136000 country: China name: Zhihua Fang role: PRINCIPAL_INVESTIGATOR lat: 43.16143 lon: 124.37785 facility: Dalian Municipal Central Hospital Affiliated of Dalian Medical University status: NOT_YET_RECRUITING city: Dalian state: Liaoning zip: 116033 country: China name: Xiaoqun Zheng role: PRINCIPAL_INVESTIGATOR lat: 38.91222 lon: 121.60222 facility: The People's Hospital of Liaoning Province status: NOT_YET_RECRUITING city: Shenyang state: Liaoning zip: 110000 country: China name: Aijie Hou role: PRINCIPAL_INVESTIGATOR lat: 41.79222 lon: 123.43278 facility: Tangdu Hospital of Fourth Military Medical University of Chinese People's Liberation Army status: NOT_YET_RECRUITING city: Xi'an state: Shaanxi zip: 710038 country: China name: Yan Li role: PRINCIPAL_INVESTIGATOR lat: 34.25833 lon: 108.92861 facility: The First Affiliated Hospital of Xi'an Jiaotong University status: NOT_YET_RECRUITING city: Xi'an state: Shaanxi zip: 710061 country: China name: Zuyi Yuan role: PRINCIPAL_INVESTIGATOR lat: 34.25833 lon: 108.92861 facility: Shaanxi provincial people's hospital status: NOT_YET_RECRUITING city: Xian state: Shaanxi zip: 710068 country: China name: Junkui Wang role: PRINCIPAL_INVESTIGATOR lat: 34.25833 lon: 108.92861 facility: Jinan Central Hospital status: NOT_YET_RECRUITING city: Jinan state: Shandong zip: 250013 country: China name: GuoHai Su role: PRINCIPAL_INVESTIGATOR lat: 36.66833 lon: 116.99722 facility: Jinan Central Hospital status: NOT_YET_RECRUITING city: Jinan state: Shandong zip: 250013 country: China name: Xiaolin Dong role: PRINCIPAL_INVESTIGATOR lat: 36.66833 lon: 116.99722 facility: Jining Medical University - Affiliated Hospital status: NOT_YET_RECRUITING city: Jining state: Shandong zip: 272029 country: China name: jinguo zhang role: PRINCIPAL_INVESTIGATOR lat: 35.405 lon: 116.58139 facility: Zhongshan Hospital,Fudan University status: NOT_YET_RECRUITING city: Shanghai state: Shanghai zip: 200032 country: China name: Wang Zhen role: PRINCIPAL_INVESTIGATOR lat: 31.22222 lon: 121.45806 facility: West China Hospital, Sichuan University status: NOT_YET_RECRUITING city: Cheng Du state: Sichuan zip: 610041 country: China name: Yong He role: PRINCIPAL_INVESTIGATOR facility: Sichuan Provincial People's Hospital status: NOT_YET_RECRUITING city: Chengdu state: Sichuan zip: 610072 country: China name: Jianhong Tao role: PRINCIPAL_INVESTIGATOR lat: 30.66667 lon: 104.06667 facility: TEDA International Cardiovascular Hospital status: NOT_YET_RECRUITING city: Tianjin state: Tianjin zip: 300457 country: China name: Jian Zhang role: PRINCIPAL_INVESTIGATOR lat: 39.14222 lon: 117.17667 facility: Tianjin Fourth Centre Hospital status: NOT_YET_RECRUITING city: Tianjin state: Tianjin zip: Tianjin country: China name: Xiaochun Xing role: PRINCIPAL_INVESTIGATOR lat: 39.14222 lon: 117.17667 facility: The First Affiliated Hospital of Xinjiang Medical University status: NOT_YET_RECRUITING city: Urumchi state: Xinjiang zip: 830054 country: China name: Xiang Ma role: PRINCIPAL_INVESTIGATOR facility: People's Hospital of Xinjiang Uygur Autonomous Region status: NOT_YET_RECRUITING city: Urumqi state: Xinjiang zip: 830001 country: China name: Hui Peng role: PRINCIPAL_INVESTIGATOR lat: 43.80096 lon: 87.60046 facility: Sir Run Run Shaw Hospital status: NOT_YET_RECRUITING city: Hangzhou state: Zhejiang zip: 310016 country: China name: Guosheng Fu role: PRINCIPAL_INVESTIGATOR lat: 30.29365 lon: 120.16142 facility: Lishui Central Hospital status: NOT_YET_RECRUITING city: Lishui City state: Zhejiang country: China name: Lingchun Lv role: PRINCIPAL_INVESTIGATOR facility: Ningbo First Hospital status: NOT_YET_RECRUITING city: Ningbo state: Zhejiang zip: 315010 country: China name: Xiaohong Fei role: PRINCIPAL_INVESTIGATOR lat: 29.87819 lon: 121.54945 facility: The First Affiliated Hospital of Wenzhou Medical University status: NOT_YET_RECRUITING city: Wenzhou state: Zhejiang zip: 325000 country: China name: Hao Zhou role: PRINCIPAL_INVESTIGATOR lat: 27.99942 lon: 120.66682 facility: Shanghai East Hospital status: NOT_YET_RECRUITING city: Shanghai zip: 200120 country: China name: Ying Li role: PRINCIPAL_INVESTIGATOR lat: 31.22222 lon: 121.45806 facility: General Hospital of Ningxia Medical University status: NOT_YET_RECRUITING city: Yinchuan zip: 750004 country: China name: xueping Ma role: PRINCIPAL_INVESTIGATOR lat: 38.46806 lon: 106.27306 facility: Kardiologická ambulance Brno status: NOT_YET_RECRUITING city: Brno state: Brno-město zip: 612 00 country: Czechia name: Jiri Parenica role: PRINCIPAL_INVESTIGATOR lat: 49.19522 lon: 16.60796 facility: EFERTUS healthcare s.r.o. status: NOT_YET_RECRUITING city: Brno state: Brno-město zip: 635 00 country: Czechia name: Hana Matejovska role: PRINCIPAL_INVESTIGATOR lat: 49.19522 lon: 16.60796 facility: Vojenská Nemocnice Brno status: NOT_YET_RECRUITING city: Brno state: Brno-město zip: 636 00 country: Czechia name: Stanislav Mihola role: PRINCIPAL_INVESTIGATOR lat: 49.19522 lon: 16.60796 facility: Fakultni Nemocnice u sv. Anny v Brne status: NOT_YET_RECRUITING city: Brno state: Brno-město zip: 656 91 country: Czechia name: Robert Prosecky role: PRINCIPAL_INVESTIGATOR lat: 49.19522 lon: 16.60796 facility: Fakultni Nemocnice u sv. Anny v Brne status: NOT_YET_RECRUITING city: Brno state: Jihomoravský Kraj zip: 60200 country: Czechia name: Vladimir Kincl role: PRINCIPAL_INVESTIGATOR lat: 49.19522 lon: 16.60796 facility: EDUMED - Náchod status: NOT_YET_RECRUITING city: Nachod state: Královéhradecký Kraj zip: 547 01 country: Czechia name: Alica Vesela role: PRINCIPAL_INVESTIGATOR lat: 50.4167 lon: 16.16289 facility: Kardiologicka ambulance status: NOT_YET_RECRUITING city: Litovel state: Olomoucký Kraj zip: 784 01 country: Czechia name: Petra Maskova role: PRINCIPAL_INVESTIGATOR lat: 49.70121 lon: 17.07615 facility: Agentura Science Pro status: NOT_YET_RECRUITING city: Olomouc state: Olomoucký Kraj zip: 779 00 country: Czechia name: Tomas Brychta role: PRINCIPAL_INVESTIGATOR lat: 49.59552 lon: 17.25175 facility: Kardiologicka a Angiologicka Ambulance status: NOT_YET_RECRUITING city: Ostrava state: Ostrava Město zip: 700 30 country: Czechia name: Dusan Kucera role: PRINCIPAL_INVESTIGATOR lat: 49.83465 lon: 18.28204 facility: Private Practice - Dr. Miroslav Koliba status: NOT_YET_RECRUITING city: Ostrava state: Ostrava Město zip: 702 00 country: Czechia name: Miroslav Koliba role: PRINCIPAL_INVESTIGATOR lat: 49.83465 lon: 18.28204 facility: Angiocentrum Komorany status: NOT_YET_RECRUITING city: Prague state: Praha 12 zip: 143 00 country: Czechia name: Ales Horacek role: PRINCIPAL_INVESTIGATOR lat: 50.08804 lon: 14.42076 facility: Poliklinika Lípa Centrum status: NOT_YET_RECRUITING city: Prague state: Praha 13 zip: 158 00 country: Czechia name: Eva Zidkova role: PRINCIPAL_INVESTIGATOR lat: 50.08804 lon: 14.42076 facility: Synexus Czech status: NOT_YET_RECRUITING city: Prague state: Praha 2 zip: 120 00 country: Czechia name: Katarina Halciakova role: PRINCIPAL_INVESTIGATOR lat: 50.08804 lon: 14.42076 facility: Nefrologie status: NOT_YET_RECRUITING city: Prague state: Praha 4 zip: 149 00 country: Czechia name: Lucie Hornova role: PRINCIPAL_INVESTIGATOR lat: 50.08804 lon: 14.42076 facility: DiaVize s.r.o. status: NOT_YET_RECRUITING city: Praha state: Praha 4 zip: 140 00 country: Czechia name: Marta Klementova role: PRINCIPAL_INVESTIGATOR lat: 50.08804 lon: 14.42076 facility: Centrum Kardiovaskularni Mediciny status: NOT_YET_RECRUITING city: Prague state: Praha 6 zip: 169 00 country: Czechia name: Jean-Claude Lubanda role: PRINCIPAL_INVESTIGATOR lat: 50.08804 lon: 14.42076 facility: Kardio Uhrineves status: NOT_YET_RECRUITING city: Prague state: Praha, Hlavní Mešto zip: 104 00 country: Czechia name: Marian Levcik role: PRINCIPAL_INVESTIGATOR lat: 50.08804 lon: 14.42076 facility: Kardiologicka ambulance status: NOT_YET_RECRUITING city: Brandýs nad Labem-Stará Boleslav state: Praha-východ zip: 250 01 country: Czechia name: Jiri Krupicka role: PRINCIPAL_INVESTIGATOR lat: 50.18709 lon: 14.66326 facility: Kardioma status: NOT_YET_RECRUITING city: Kolin state: Středočeský Kraj zip: 280 02 country: Czechia name: Vit Maratka role: PRINCIPAL_INVESTIGATOR lat: 50.02806 lon: 15.1998 facility: Nova kardiologie - Kardiologicka ambulance status: NOT_YET_RECRUITING city: Ricany state: Středočeský Kraj zip: 251 01 country: Czechia name: Jan Kohoutek role: PRINCIPAL_INVESTIGATOR lat: 49.99168 lon: 14.65427 facility: Clinical Trials Service s.r.o. status: NOT_YET_RECRUITING city: Uherské Hradiště state: Zlínský Kraj zip: 686 01 country: Czechia name: Vladimir Cech role: PRINCIPAL_INVESTIGATOR lat: 49.06975 lon: 17.45969 facility: PreventaMed status: NOT_YET_RECRUITING city: Olomouc zip: 779 00 country: Czechia name: Jiri Pumprla role: PRINCIPAL_INVESTIGATOR lat: 49.59552 lon: 17.25175 facility: Kardiologicka ambulance MUDr. Ferkl s.r.o. status: NOT_YET_RECRUITING city: Trutnov zip: 541 01 country: Czechia name: Richard Ferkl role: PRINCIPAL_INVESTIGATOR lat: 50.56101 lon: 15.9127 facility: Cardio Research, s.r.o status: NOT_YET_RECRUITING city: Zlín zip: 760 01 country: Czechia name: Tomas Fiala role: PRINCIPAL_INVESTIGATOR lat: 49.22645 lon: 17.67065 facility: Rigshospitalet status: NOT_YET_RECRUITING city: Copenhagen state: Hovedstaden zip: 2100 country: Denmark name: Christian Hassager role: PRINCIPAL_INVESTIGATOR lat: 55.67594 lon: 12.56553 facility: Herlev and Gentofte Hospital status: NOT_YET_RECRUITING city: Hellerup state: Hovedstaden zip: 2900 country: Denmark name: Gunnar Gislason role: PRINCIPAL_INVESTIGATOR lat: 55.73204 lon: 12.57093 facility: Sanos Clinic status: NOT_YET_RECRUITING city: Herlev state: Hovedstaden zip: 2730 country: Denmark name: Bernt Husoy role: PRINCIPAL_INVESTIGATOR lat: 55.72366 lon: 12.43998 facility: Aarhus Universitetshospital, Skejby status: NOT_YET_RECRUITING city: Aarhus state: Midtjylland zip: 8200 country: Denmark name: Henrik Wiggers role: PRINCIPAL_INVESTIGATOR lat: 56.15674 lon: 10.21076 facility: Sanos Clinic - Nordjylland status: NOT_YET_RECRUITING city: Gandrup state: Nordjylland zip: 9362 country: Denmark name: Cecilie Rovsing role: PRINCIPAL_INVESTIGATOR lat: 56.74249 lon: 9.82298 facility: Holbæk Sygehus status: NOT_YET_RECRUITING city: Holbaek state: Sjælland zip: 4300 country: Denmark name: Morten Lindhardt role: PRINCIPAL_INVESTIGATOR lat: 55.71354 lon: 11.7169 facility: Sygehus Sønderjylland i Aabenraa status: NOT_YET_RECRUITING city: Aabenraa state: Syddanmark zip: 6200 country: Denmark name: Frank-Peter Elpert role: PRINCIPAL_INVESTIGATOR lat: 55.04434 lon: 9.41741 facility: Sydvestjysk Sygehus Esbjerg status: NOT_YET_RECRUITING city: Esbjerg state: Syddanmark zip: 6700 country: Denmark name: Kristian Korsgaard Thomsen role: PRINCIPAL_INVESTIGATOR lat: 55.47028 lon: 8.45187 facility: Sanos Clinic - Syddanmark status: NOT_YET_RECRUITING city: Vejle state: Syddanmark zip: 7100 country: Denmark name: Peter Alexandersen role: PRINCIPAL_INVESTIGATOR lat: 55.70927 lon: 9.5357 facility: CHU de Nice status: NOT_YET_RECRUITING city: Nice state: Alpes-Maritimes zip: 06000 country: France name: Emile Ferrari role: PRINCIPAL_INVESTIGATOR lat: 43.70313 lon: 7.26608 facility: CHU Strasbourg-Hautepierre status: NOT_YET_RECRUITING city: Strasbourg state: Alsace zip: 67098 country: France name: Alain Pradignac role: PRINCIPAL_INVESTIGATOR lat: 48.58392 lon: 7.74553 facility: CHU Bordeaux Haut-Leveque status: NOT_YET_RECRUITING city: Pessac state: Aquitaine zip: 33600 country: France name: Sami FAWAZ role: PRINCIPAL_INVESTIGATOR lat: 44.81011 lon: -0.64129 facility: Hôpital Saint Joseph status: NOT_YET_RECRUITING city: Marseille state: Bouches-du-Rhône zip: 13285 country: France name: Patrick KHANOYAN role: PRINCIPAL_INVESTIGATOR lat: 43.29551 lon: 5.38958 facility: Centre Hospitalier Universitaire Dijon Bourgogne - Hôpital François Mitterrand status: NOT_YET_RECRUITING city: Dijon state: Bourgogne zip: 21079 country: France name: FREDERIC CHAGUE role: PRINCIPAL_INVESTIGATOR lat: 47.31667 lon: 5.01667 facility: Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou status: NOT_YET_RECRUITING city: Rennes state: Bretagne zip: 35033 country: France name: francois paillard role: PRINCIPAL_INVESTIGATOR lat: 48.11198 lon: -1.67429 facility: CHRU Troussau status: NOT_YET_RECRUITING city: Chambray Les Tours state: Centre zip: 37170 country: France name: Fabrice Ivanes role: PRINCIPAL_INVESTIGATOR lat: 47.33537 lon: 0.70286 facility: CHU Besançon status: NOT_YET_RECRUITING city: Besançon state: Doubs zip: 25000 country: France name: francois schiele role: PRINCIPAL_INVESTIGATOR lat: 47.24878 lon: 6.01815 facility: Centre Hospitalier Louis Pasteur status: NOT_YET_RECRUITING city: Le Coudray state: Eure-et-Loir zip: 28630 country: France name: Gregoire Range role: PRINCIPAL_INVESTIGATOR lat: 48.42115 lon: 1.50057 facility: Centre Hospitalier Universitaire de Nîmes - Hôpital Universitaire Carémeau status: NOT_YET_RECRUITING city: Nîmes state: Gard zip: 30029 country: France name: Guillaume Cayla role: PRINCIPAL_INVESTIGATOR lat: 43.83333 lon: 4.35 facility: CHU Rangueil status: NOT_YET_RECRUITING city: Toulouse state: Haute-Garonne zip: 31059 country: France name: Meyer Elbaz role: PRINCIPAL_INVESTIGATOR lat: 43.60426 lon: 1.44367 facility: CHU Charles Nicolle status: NOT_YET_RECRUITING city: Rouen state: Haute-Normandie zip: 76031 country: France name: Eric Durand role: PRINCIPAL_INVESTIGATOR lat: 49.44313 lon: 1.09932 facility: CHU Montpellier Lapeyronie Hospital status: NOT_YET_RECRUITING city: Montpellier state: Hérault zip: 34295 country: France name: ariane Sultan role: PRINCIPAL_INVESTIGATOR lat: 43.61092 lon: 3.87723 facility: Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes status: NOT_YET_RECRUITING city: Nantes Cedex 1 state: Loire-Atlantique zip: 44093 country: France name: Bertrand CARIOU role: PRINCIPAL_INVESTIGATOR lat: 47.21725 lon: -1.55336 facility: Hopital Claude Huriez - CHU de Lille status: NOT_YET_RECRUITING city: Lille state: Nord zip: 59037 country: France name: cecile yelnik role: PRINCIPAL_INVESTIGATOR lat: 50.63297 lon: 3.05858 facility: Centre Hospitalier Compiègne-Noyon status: NOT_YET_RECRUITING city: Compiègne state: Oise zip: 60200 country: France name: Jerome Clerc role: PRINCIPAL_INVESTIGATOR lat: 49.41794 lon: 2.82606 facility: Pitie Salpetriere University Hospital status: NOT_YET_RECRUITING city: Paris state: Orne zip: 75013 country: France name: Antonio Gallo role: PRINCIPAL_INVESTIGATOR lat: 48.85341 lon: 2.3488 facility: Centre Hospitalier de Pau status: NOT_YET_RECRUITING city: Pau state: Pyrénées-Atlantiques zip: 64000 country: France name: NICOLAS DELARCHE role: PRINCIPAL_INVESTIGATOR lat: 43.3 lon: -0.36667 facility: Centre Hospitalier Saint Joseph - Saint Luc status: NOT_YET_RECRUITING city: Lyon state: Rhône-Alpes zip: 69007 country: France name: Lucien MARCHAND role: PRINCIPAL_INVESTIGATOR lat: 45.74848 lon: 4.84669 facility: Hospices Civils de Lyon - Hopital Louis Pradel status: NOT_YET_RECRUITING city: Bron state: Rhône zip: 69677 country: France name: Hospices Civils de Lyon - Hopital Louis Pradel role: PRINCIPAL_INVESTIGATOR lat: 45.73333 lon: 4.91667 facility: Hôpital Bichat - Claude-Bernard status: NOT_YET_RECRUITING city: Paris zip: 75018 country: France name: Gabriel Steg role: PRINCIPAL_INVESTIGATOR lat: 48.85341 lon: 2.3488 facility: Polyclinique Vauban status: NOT_YET_RECRUITING city: Valenciennes zip: 59300 country: France name: Sebastien Caudmont role: PRINCIPAL_INVESTIGATOR lat: 50.35 lon: 3.53333 facility: Hôpital Avicenne status: NOT_YET_RECRUITING city: Bobigny state: Île-de-France zip: 93000 country: France name: Emmanuel Cosson role: PRINCIPAL_INVESTIGATOR lat: 48.9 lon: 2.45 facility: Hôpital Européen Georges Pompidou status: NOT_YET_RECRUITING city: Paris state: Île-de-France zip: 75015 country: France name: Sebastien CZERNICHOW role: PRINCIPAL_INVESTIGATOR lat: 48.85341 lon: 2.3488 facility: Hôpital Saint Antoine status: NOT_YET_RECRUITING city: Paris state: Île-de-France zip: 75571 country: France name: FRANCK BOCCARA role: PRINCIPAL_INVESTIGATOR lat: 48.85341 lon: 2.3488 facility: ze:ro ARZTPRAXEN status: RECRUITING city: Mannheim state: Baden-Württemberg zip: 68165 country: Germany name: Peter Salbach role: PRINCIPAL_INVESTIGATOR lat: 49.4891 lon: 8.46694 facility: Universitätsmedizin Mannheim status: RECRUITING city: Mannheim state: Baden-Württemberg zip: 68167 country: Germany name: Ksenija Stach-Jablonski role: PRINCIPAL_INVESTIGATOR lat: 49.4891 lon: 8.46694 facility: Studienzentrum Herzklinik Ulm MVZ status: NOT_YET_RECRUITING city: Ulm state: Baden-Württemberg zip: 89077 country: Germany name: Norbert Jahnke role: PRINCIPAL_INVESTIGATOR lat: 48.39841 lon: 9.99155 facility: Deutsches Herzzentrum München status: RECRUITING city: Munich state: Bayern zip: 80636 country: Germany name: Wolfgang Koenig role: PRINCIPAL_INVESTIGATOR lat: 48.13743 lon: 11.57549 facility: Universitätsklinikum Regensburg status: NOT_YET_RECRUITING city: Regensburg state: Bayern zip: 93053 country: Germany name: Andrea Baessler role: PRINCIPAL_INVESTIGATOR lat: 49.01513 lon: 12.10161 facility: Kardiologische Gemeinschaftspraxis am Park Sanssouci status: NOT_YET_RECRUITING city: Potsdam state: Brandenburg zip: 14471 country: Germany name: Regina Gaub role: PRINCIPAL_INVESTIGATOR lat: 52.39886 lon: 13.06566 facility: Kardiologische Praxis Dr. med. univ. Wolfgang Jungmair status: NOT_YET_RECRUITING city: Bad Homburg state: Hessen zip: 61348 country: Germany name: Wolfgang Alfred Jungmair role: PRINCIPAL_INVESTIGATOR lat: 50.22683 lon: 8.61816 facility: Cardioangiologisches Centrum Bethanien status: NOT_YET_RECRUITING city: Frankfurt state: Hessen zip: 60389 country: Germany name: Holger Eggebrecht role: PRINCIPAL_INVESTIGATOR lat: 50.11552 lon: 8.68417 facility: Diabetes Zentrum Dr. Tews status: NOT_YET_RECRUITING city: Gelnhausen state: Hessen zip: 63571 country: Germany name: Dietrich Tews role: PRINCIPAL_INVESTIGATOR lat: 50.20164 lon: 9.18742 facility: GPR Gesundheits- und Pflegezentrum Rüsselsheim status: NOT_YET_RECRUITING city: Rüsselsheim state: Hessen zip: 65428 country: Germany name: Ehab Shahock role: PRINCIPAL_INVESTIGATOR lat: 49.98955 lon: 8.42251 facility: Praxis Oedeme status: NOT_YET_RECRUITING city: Lüneburg state: Niedersachsen zip: 21339 country: Germany name: Hans-Eckart Sarnighausen role: PRINCIPAL_INVESTIGATOR lat: 53.2509 lon: 10.41409 facility: Universitätsklinikum Aachen status: RECRUITING city: Aachen state: Nordrhein-Westfalen zip: 52074 country: Germany name: Julia Brandts role: PRINCIPAL_INVESTIGATOR lat: 50.77664 lon: 6.08342 facility: Klinikum Bielefeld Mitte status: NOT_YET_RECRUITING city: Bielefeld state: Nordrhein-Westfalen zip: 33604 country: Germany name: Christoph Stellbrink role: PRINCIPAL_INVESTIGATOR lat: 52.03333 lon: 8.53333 facility: Medizentrum Essen Borbeck status: NOT_YET_RECRUITING city: Essen state: Nordrhein-Westfalen zip: 45355 country: Germany name: Axel Schaefer role: PRINCIPAL_INVESTIGATOR lat: 51.45657 lon: 7.01228 facility: University Hospital of Cologne status: NOT_YET_RECRUITING city: Köln state: Nordrhein-Westfalen zip: 50937 country: Germany name: Ioanna Gouni-Berthold role: PRINCIPAL_INVESTIGATOR lat: 50.93333 lon: 6.95 facility: Institut für Diabetesforschung GmbH Münster status: NOT_YET_RECRUITING city: Münster state: Nordrhein-Westfalen zip: 48145 country: Germany name: Ludger Rose role: PRINCIPAL_INVESTIGATOR lat: 51.96236 lon: 7.62571 facility: Universitaet zu Koeln - Sana-Klinikum Remscheid GmbH - Klinik fuer Kardiologie, Pneumologie und Internisti -T status: NOT_YET_RECRUITING city: Remscheid state: Nordrhein-Westfalen zip: 42859 country: Germany name: Burkhard Sievers role: PRINCIPAL_INVESTIGATOR lat: 51.17983 lon: 7.1925 facility: Zentrum für klinische Studien status: RECRUITING city: Saint Ingbert state: Saarland zip: 66386 country: Germany name: Alexander Segner role: PRINCIPAL_INVESTIGATOR facility: Otto-von-Guericke-Universität Magdeburg status: NOT_YET_RECRUITING city: Magdeburg state: Sachsen-Anhalt zip: 39120 country: Germany name: Rüdiger Braun-Dullaeus role: PRINCIPAL_INVESTIGATOR lat: 52.12773 lon: 11.62916 facility: Hausärztlich-Kardiologisches MVZ am Felsenkeller GmbH/Zentrum für klinische Studien status: NOT_YET_RECRUITING city: Dresden state: Sachsen zip: 01277 country: Germany name: Maria Kaiser role: PRINCIPAL_INVESTIGATOR lat: 51.05089 lon: 13.73832 facility: Herzzentrum Dresden GmbH Universitätsklinik status: NOT_YET_RECRUITING city: Dresden state: Sachsen zip: 01307 country: Germany name: Felix Matthias Heidrich role: PRINCIPAL_INVESTIGATOR lat: 51.05089 lon: 13.73832 facility: Universitaetsklinikum Carl Gustav Carus Dresden status: NOT_YET_RECRUITING city: Dresden state: Sachsen zip: 01307 country: Germany name: Nikolaos Perakakis role: PRINCIPAL_INVESTIGATOR lat: 51.05089 lon: 13.73832 facility: Universitätsklinikum Leipzig status: NOT_YET_RECRUITING city: Leipzig state: Sachsen zip: 04103 country: Germany name: Irina Mueller-Kozarez role: PRINCIPAL_INVESTIGATOR lat: 51.33962 lon: 12.37129 facility: Herzzentrum Leipzig GmbH status: NOT_YET_RECRUITING city: Leipzig state: Sachsen zip: 04289 country: Germany name: Holger Thiele role: PRINCIPAL_INVESTIGATOR lat: 51.33962 lon: 12.37129 facility: Universitätsklinikum Jena status: NOT_YET_RECRUITING city: Jena state: Thüringen zip: 07747 country: Germany name: Oliver Weingärtner role: PRINCIPAL_INVESTIGATOR lat: 50.92878 lon: 11.5899 facility: Klinikum am Plattenwald status: NOT_YET_RECRUITING city: Bad Friedrichshall zip: 74177 country: Germany name: Thomas Dengler role: PRINCIPAL_INVESTIGATOR facility: Kardiologische Praxen im Spreebogen status: NOT_YET_RECRUITING city: Berlin zip: 10559 country: Germany name: Florian Krackhardt role: PRINCIPAL_INVESTIGATOR lat: 52.52437 lon: 13.41053 facility: Praxis Rankestrasse status: NOT_YET_RECRUITING city: Berlin zip: 10789 country: Germany name: Werner Albert Rieker role: PRINCIPAL_INVESTIGATOR lat: 52.52437 lon: 13.41053 facility: DRK Kliniken Berlin - Köpenick status: NOT_YET_RECRUITING city: Berlin zip: 12559 country: Germany name: Martin Lange role: PRINCIPAL_INVESTIGATOR lat: 52.52437 lon: 13.41053 facility: Charité Campus Virchow-Klinikum status: NOT_YET_RECRUITING city: Berlin zip: 13353 country: Germany name: Ursula Kassner role: PRINCIPAL_INVESTIGATOR lat: 52.52437 lon: 13.41053 facility: Cardiologicum Hamburg status: NOT_YET_RECRUITING city: Hamburg zip: 22041 country: Germany name: Martin W. Bergmann role: PRINCIPAL_INVESTIGATOR lat: 53.57532 lon: 10.01534 facility: Iatriko Paleou Falirou Medical Center status: NOT_YET_RECRUITING city: Paleo Faliro state: Attikí (Region) zip: 17562 country: Greece name: John Doupis role: PRINCIPAL_INVESTIGATOR facility: Athens Naval Hospital status: NOT_YET_RECRUITING city: Athens state: Attikí zip: 11521 country: Greece name: Anastasios Milkas role: PRINCIPAL_INVESTIGATOR lat: 37.97945 lon: 23.71622 facility: General Hospital of Athens Laiko status: NOT_YET_RECRUITING city: Athens state: Attikí zip: 11527 country: Greece name: Evangelos Liberopoulos role: PRINCIPAL_INVESTIGATOR lat: 37.97945 lon: 23.71622 facility: Athens Medical Center status: NOT_YET_RECRUITING city: Athens state: Attikí zip: 151 25 country: Greece name: Georgia Argyrakopoulou role: PRINCIPAL_INVESTIGATOR lat: 37.97945 lon: 23.71622 facility: Attikon General University Hospital status: NOT_YET_RECRUITING city: Chaidari state: Attikí zip: 12462 country: Greece name: Vaia Lambadiari role: PRINCIPAL_INVESTIGATOR lat: 38.01135 lon: 23.66597 facility: University Hospital of Ioannina status: NOT_YET_RECRUITING city: Ioannina state: Ioánnina zip: 45500 country: Greece name: Vasileios Tsimichodimos role: PRINCIPAL_INVESTIGATOR lat: 39.66486 lon: 20.85189 facility: University General Hospital of Heraklion status: NOT_YET_RECRUITING city: Heraklion state: Irakleío zip: 71110 country: Greece name: Theodosios Filippatos role: PRINCIPAL_INVESTIGATOR lat: 35.32787 lon: 25.14341 facility: AHEPA University General Hospital of Thessaloniki status: NOT_YET_RECRUITING city: Thessaloniki state: Kentrikí Makedonía zip: 546 36 country: Greece name: Konstantinos Tziomalos role: PRINCIPAL_INVESTIGATOR lat: 40.64361 lon: 22.93086 facility: Papageorgiou General Hospital of Thessaloniki status: NOT_YET_RECRUITING city: Thessaloniki state: Thessaloníki zip: 564 29 country: Greece name: Glykeria Tzatzagou role: PRINCIPAL_INVESTIGATOR lat: 40.64361 lon: 22.93086 facility: Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ status: NOT_YET_RECRUITING city: Szeged state: Csongrád zip: 6725 country: Hungary name: Robert Takacs role: PRINCIPAL_INVESTIGATOR lat: 46.253 lon: 20.14824 facility: Vita Verum Medical Egeszsegugyi Szolgaltato status: NOT_YET_RECRUITING city: Szekesfehervar state: Fejér zip: 8000 country: Hungary name: Amalia Benedek role: PRINCIPAL_INVESTIGATOR lat: 47.18995 lon: 18.41034 facility: Medifarma 98 Kft status: NOT_YET_RECRUITING city: Nyiregyhaza state: Nyíregyháza zip: 4400 country: Hungary name: Zsolt Zilahi role: PRINCIPAL_INVESTIGATOR lat: 47.95539 lon: 21.71671 facility: DRC Gyógyszervizsgáló Központ status: NOT_YET_RECRUITING city: Balatongyorok state: Veszprém zip: 8313 country: Hungary name: Margit Dudás role: PRINCIPAL_INVESTIGATOR lat: 46.75833 lon: 17.35462 facility: Belvárosi Egészségház status: NOT_YET_RECRUITING city: Zalaegerszeg state: Zala zip: 8900 country: Hungary name: Geza Lupkovics role: PRINCIPAL_INVESTIGATOR lat: 46.84 lon: 16.84389 facility: Szent Margit Rendelőintézet Nonprofit Kft status: NOT_YET_RECRUITING city: Budapest zip: 1032 country: Hungary name: Timea Tänczer role: PRINCIPAL_INVESTIGATOR lat: 47.49801 lon: 19.03991 facility: Magyar Honvedseg Egeszsegugyi Kozpont status: NOT_YET_RECRUITING city: Budapest zip: 1062 country: Hungary name: Erika Maria Hubina role: PRINCIPAL_INVESTIGATOR lat: 47.49801 lon: 19.03991 facility: Semmelweis University status: NOT_YET_RECRUITING city: Budapest zip: 1122 country: Hungary name: Béla Merkely role: PRINCIPAL_INVESTIGATOR lat: 47.49801 lon: 19.03991 facility: Privát Doktor Egészségügyi Zrt status: NOT_YET_RECRUITING city: Budapest zip: 1132 country: Hungary name: Andras R Vertes role: PRINCIPAL_INVESTIGATOR lat: 47.49801 lon: 19.03991 facility: Debreceni Egyetem Klinikai Kozpont status: NOT_YET_RECRUITING city: Debrecen zip: 4032 country: Hungary name: Denes Pall role: PRINCIPAL_INVESTIGATOR lat: 47.53333 lon: 21.63333 facility: All India Institute of Medical Sciences status: NOT_YET_RECRUITING city: Raipur state: Chhattisgarh zip: 492099 country: India name: Satyajit Singh role: PRINCIPAL_INVESTIGATOR lat: 21.23333 lon: 81.63333 facility: G.B. Pant Institute of Postgraduate Medical Education & Research status: NOT_YET_RECRUITING city: New Delhi state: Delhi zip: 110002 country: India name: Vimal Mehta role: PRINCIPAL_INVESTIGATOR lat: 28.63576 lon: 77.22445 facility: KLES Dr. Prabhakar Kore Hospital & M.R.C status: NOT_YET_RECRUITING city: Belagavi state: Karnataka zip: 590010 country: India name: Prasad M R role: PRINCIPAL_INVESTIGATOR facility: Lisie Hospital status: NOT_YET_RECRUITING city: Kochi state: Kerala zip: 682018 country: India name: Jabir Abdullakutty role: PRINCIPAL_INVESTIGATOR lat: 9.93988 lon: 76.26022 facility: Government Medical College - Kozhikode status: NOT_YET_RECRUITING city: Kozhikode state: Kerala zip: 673008 country: India name: Neeraj Manikath role: PRINCIPAL_INVESTIGATOR lat: 11.24802 lon: 75.7804 facility: Vijan Hospital & Research Centre status: NOT_YET_RECRUITING city: Nashik state: Maharashtra zip: 422005 country: India name: Vikrant Vijan role: PRINCIPAL_INVESTIGATOR lat: 19.99727 lon: 73.79096 facility: Sardar Patel Medical College status: NOT_YET_RECRUITING city: Bikaner state: Rajasthan zip: 334001 country: India name: Devendra Agarwal role: PRINCIPAL_INVESTIGATOR lat: 28.01762 lon: 73.31495 facility: K care Hospital status: NOT_YET_RECRUITING city: Kanpur state: Uttar Pradesh zip: 208001 country: India name: Amit Kumar Gupta role: PRINCIPAL_INVESTIGATOR lat: 26.46523 lon: 80.34975 facility: King George's Medical University status: NOT_YET_RECRUITING city: Lucknow state: Uttar Pradesh zip: 226003 country: India name: S. K. Dwivedi role: PRINCIPAL_INVESTIGATOR lat: 26.83928 lon: 80.92313 facility: Shri Mahant Indiresh Hospital status: NOT_YET_RECRUITING city: Dehradun state: Uttarakhand zip: 248001 country: India name: Tanuj Bhatia role: PRINCIPAL_INVESTIGATOR lat: 30.32295 lon: 78.03168 facility: Soroka Medical Center status: NOT_YET_RECRUITING city: Be'er Sheva state: HaDarom zip: 8410101 country: Israel name: Itzhak Gabizon role: PRINCIPAL_INVESTIGATOR lat: 31.25181 lon: 34.7913 facility: Edith Wolfson Medical Center status: NOT_YET_RECRUITING city: Holon state: HaMerkaz zip: 5810001 country: Israel name: orit twito role: PRINCIPAL_INVESTIGATOR lat: 32.01034 lon: 34.77918 facility: Meir Medical Center status: NOT_YET_RECRUITING city: Kfar Saba state: HaMerkaz zip: 4428164 country: Israel name: Victor Vishlitzky role: PRINCIPAL_INVESTIGATOR lat: 32.175 lon: 34.90694 facility: Rabin Medical Center status: NOT_YET_RECRUITING city: Petah Tikva state: HaMerkaz zip: 4941492 country: Israel name: Avishay Elis role: PRINCIPAL_INVESTIGATOR lat: 32.08707 lon: 34.88747 facility: Rabin Medical Center status: NOT_YET_RECRUITING city: Petah-Tikva state: HaMerkaz zip: 4941492 country: Israel name: Alejandro Solodky role: PRINCIPAL_INVESTIGATOR lat: 32.08707 lon: 34.88747 facility: Sheba Medical Center status: NOT_YET_RECRUITING city: Ramat Gan state: HaMerkaz zip: 5262100 country: Israel name: Michael Shechter role: PRINCIPAL_INVESTIGATOR lat: 32.08227 lon: 34.81065 facility: Sheba Medical Center status: NOT_YET_RECRUITING city: Ramat Gan state: HaMerkaz zip: 5265601 country: Israel name: Hofit Cohen role: PRINCIPAL_INVESTIGATOR lat: 32.08227 lon: 34.81065 facility: Kaplan Medical Center status: NOT_YET_RECRUITING city: Rehovot state: HaMerkaz zip: 7610001 country: Israel name: Viviana Ostrovsky role: PRINCIPAL_INVESTIGATOR lat: 31.89421 lon: 34.81199 facility: Rambam Health Care Campus status: RECRUITING city: Haifa state: HaTsafon zip: 3109601 country: Israel name: oren caspi role: PRINCIPAL_INVESTIGATOR lat: 32.81841 lon: 34.9885 facility: Galilee Medical Center status: NOT_YET_RECRUITING city: Nahariya state: HaTsafon zip: 2210001 country: Israel name: Shaul Atar role: PRINCIPAL_INVESTIGATOR lat: 33.00892 lon: 35.09814 facility: Sourasky Medical Center status: NOT_YET_RECRUITING city: Tel Aviv state: Tell Abīb zip: 6423906 country: Israel name: Elena Izkhakov role: PRINCIPAL_INVESTIGATOR lat: 32.08088 lon: 34.78057 facility: Sourasky Medical Center status: NOT_YET_RECRUITING city: Tel Aviv state: Tell Abīb zip: 6423906 country: Israel name: Yaron Arbel role: PRINCIPAL_INVESTIGATOR lat: 32.08088 lon: 34.78057 facility: Shaare Zedek Medical Center status: NOT_YET_RECRUITING city: Jerusalem state: Yerushalayim zip: 9013102 country: Israel name: Dov Gavish role: PRINCIPAL_INVESTIGATOR lat: 31.76904 lon: 35.21633 facility: Hadassah Medical Center status: RECRUITING city: Jerusalem state: Yerushalayim zip: 9112001 country: Israel name: Ronen Durst role: PRINCIPAL_INVESTIGATOR lat: 31.76904 lon: 35.21633 facility: Hadassah Medical Center status: RECRUITING city: Jerusalem state: Yerushalayim zip: 9112001 country: Israel name: Daniel Schurr role: PRINCIPAL_INVESTIGATOR lat: 31.76904 lon: 35.21633 facility: Rambam Health Care Campus status: NOT_YET_RECRUITING city: Haifa state: Ḥeifā zip: 3109601 country: Israel name: Tony Hayek role: PRINCIPAL_INVESTIGATOR lat: 32.81841 lon: 34.9885 facility: Carmel Hospital status: NOT_YET_RECRUITING city: Haifa state: Ḥeifā zip: 3436212 country: Israel name: BARAK ZAFRIR role: PRINCIPAL_INVESTIGATOR lat: 32.81841 lon: 34.9885 facility: Azienda Ospedaliero Universitaria S.Anna status: NOT_YET_RECRUITING city: Ferrara state: Emilia-Romagna zip: 44100 country: Italy name: Alessandro Fucili role: PRINCIPAL_INVESTIGATOR lat: 44.83804 lon: 11.62057 facility: Policlinico Umberto I status: NOT_YET_RECRUITING city: Rome state: Lazio zip: 00161 country: Italy name: Marcello Arca role: PRINCIPAL_INVESTIGATOR lat: 41.89193 lon: 12.51133 facility: Ospedale San Martino status: NOT_YET_RECRUITING city: Genova state: Liguria zip: 16132 country: Italy name: LIVIA PISCIOTTA role: PRINCIPAL_INVESTIGATOR lat: 44.40478 lon: 8.94438 facility: Ospedale Bassini status: NOT_YET_RECRUITING city: Cinisello Balsamo state: Milano zip: 20092 country: Italy name: Paolo Fabbrini role: PRINCIPAL_INVESTIGATOR lat: 45.55823 lon: 9.21495 facility: Centro Cardiologico Monzino status: NOT_YET_RECRUITING city: Milan state: Milano zip: 20138 country: Italy name: José Pablo Werba role: SUB_INVESTIGATOR lat: 45.46427 lon: 9.18951 facility: ASST Grande Ospedale Metropolitano Niguarda status: NOT_YET_RECRUITING city: Milan state: Milano zip: 20162 country: Italy name: Alessandro Maloberti role: PRINCIPAL_INVESTIGATOR lat: 45.46427 lon: 9.18951 facility: Ospedale di Baggiovara status: NOT_YET_RECRUITING city: Baggiovara state: Modena zip: 41126 country: Italy name: Fabio Nascimbeni role: PRINCIPAL_INVESTIGATOR lat: 44.60416 lon: 10.86256 facility: Azienda Ospedaliera Universitaria Careggi status: NOT_YET_RECRUITING city: Firenze state: Toscana zip: 50134 country: Italy name: rossella marcucci role: PRINCIPAL_INVESTIGATOR lat: 43.77925 lon: 11.24626 facility: Azienda Ospedaliera Universitaria Pisana status: NOT_YET_RECRUITING city: Pisa state: Toscana zip: 56124 country: Italy name: Ferruccio Santini role: PRINCIPAL_INVESTIGATOR lat: 43.70853 lon: 10.4036 facility: Fondazione G. Monasterio status: NOT_YET_RECRUITING city: Pisa state: Toscana zip: 56124 country: Italy name: Francesco Sbrana role: PRINCIPAL_INVESTIGATOR lat: 43.70853 lon: 10.4036 facility: Ospedale Cazzavillan di Arzignano status: NOT_YET_RECRUITING city: Arzignano state: Veneto zip: 36071 country: Italy name: Claudio Bilato role: PRINCIPAL_INVESTIGATOR lat: 45.52027 lon: 11.33446 facility: Azienda Ospedaliera di Padova status: NOT_YET_RECRUITING city: Padova state: Veneto zip: 35128 country: Italy name: Alberto Zambon role: PRINCIPAL_INVESTIGATOR lat: 45.40797 lon: 11.88586 facility: IRCCS - AOU di Bologna status: NOT_YET_RECRUITING city: Bologna zip: 40138 country: Italy name: Claudio Borghi role: PRINCIPAL_INVESTIGATOR lat: 44.49381 lon: 11.33875 facility: Ospedale San Raffaele status: NOT_YET_RECRUITING city: Milano zip: 20132 country: Italy name: Emanuela Setola role: PRINCIPAL_INVESTIGATOR lat: 45.46427 lon: 9.18951 facility: Hospital Santa Maria della Misericordia in Perugia status: NOT_YET_RECRUITING city: Perugia zip: 06156 country: Italy name: Matteo Pirro role: PRINCIPAL_INVESTIGATOR lat: 43.1122 lon: 12.38878 facility: Kasugai Municipal Hospital status: RECRUITING city: Kasugai state: Aichi zip: 486-8510 country: Japan name: Mitsutoshi Oguri role: PRINCIPAL_INVESTIGATOR lat: 35.24762 lon: 136.97229 facility: Nagoya City University Hospital status: NOT_YET_RECRUITING city: Nagoya state: Aichi zip: 467-8602 country: Japan name: Tomohiro Tanaka role: PRINCIPAL_INVESTIGATOR lat: 35.18147 lon: 136.90641 facility: Asahi Hospital - Asahi status: RECRUITING city: Asahi state: Chiba zip: 289-2511 country: Japan name: Shunichi Kushida role: PRINCIPAL_INVESTIGATOR lat: 35.71667 lon: 140.65 facility: Saiseikai Futsukaichi Hospital status: RECRUITING city: Chikushino state: Fukuoka zip: 818-8516 country: Japan name: Toshiaki Kadokami role: PRINCIPAL_INVESTIGATOR lat: 33.49631 lon: 130.5156 facility: Kokura Memorial Hospital status: NOT_YET_RECRUITING city: Kitakyushu state: Fukuoka zip: 802-8555 country: Japan name: Kenji Ando role: PRINCIPAL_INVESTIGATOR lat: 33.85181 lon: 130.85034 facility: Chugoku Rosai Hospital status: NOT_YET_RECRUITING city: Kure state: Hiroshima zip: 737-0193 country: Japan name: Keiji Matsuda role: PRINCIPAL_INVESTIGATOR lat: 34.23222 lon: 132.56658 facility: Asahikawa City Hospital status: RECRUITING city: Asahikawa state: Hokkaido zip: 070-8610 country: Japan name: Yoshihiro Miyamoto role: PRINCIPAL_INVESTIGATOR lat: 43.77063 lon: 142.36489 facility: Hospital Hakodate Hokkaido status: NOT_YET_RECRUITING city: Hakodate state: Hokkaido zip: 041-8680 country: Japan name: Yusuke Tokuda role: PRINCIPAL_INVESTIGATOR lat: 41.77583 lon: 140.73667 facility: Tokeidai Memorial Hospital status: NOT_YET_RECRUITING city: Sapporo state: Hokkaido zip: 060-0031 country: Japan name: Michinao Tan role: PRINCIPAL_INVESTIGATOR lat: 43.06667 lon: 141.35 facility: Sapporo Medical University Hospital status: NOT_YET_RECRUITING city: Sapporo state: Hokkaido zip: 060-8543 country: Japan name: Masato Furuhashi role: PRINCIPAL_INVESTIGATOR lat: 43.06667 lon: 141.35 facility: Japan Community Healthcare Organization Hokkaido Hospital status: RECRUITING city: Sapporo state: Hokkaido zip: 062-8618 country: Japan name: Masashige Takahashi role: PRINCIPAL_INVESTIGATOR lat: 43.06667 lon: 141.35 facility: Hyogo Prefectural Harima-Himeji General Medical Center status: RECRUITING city: Himeji state: Hyogo zip: 670-8560 country: Japan name: Tomofumi Takaya role: PRINCIPAL_INVESTIGATOR lat: 34.81667 lon: 134.7 facility: Kobe City Medical Center General Hospital status: NOT_YET_RECRUITING city: Kobe state: Hyogo zip: 650-0047 country: Japan name: Yutaka Furukawa role: PRINCIPAL_INVESTIGATOR lat: 34.6913 lon: 135.183 facility: Higashi Takarazuka Satoh Hospital status: RECRUITING city: Takarazuka state: Hyogo zip: 665-0873 country: Japan name: Katsuyuki Hasegawa role: PRINCIPAL_INVESTIGATOR lat: 34.79936 lon: 135.35697 facility: Takasago Seibu Hospital status: RECRUITING city: Takasago state: Hyogo zip: 676-0812 country: Japan name: Katsunari Matsuoka role: PRINCIPAL_INVESTIGATOR facility: Tsuchiura Kyodo General Hospital status: RECRUITING city: Tsuchiura state: Ibaraki zip: 300-0028 country: Japan name: TSUNEKAZU KAKUTA role: PRINCIPAL_INVESTIGATOR lat: 36.09047 lon: 140.21047 facility: Public Matto Ishikawa Central Hospital status: NOT_YET_RECRUITING city: Hakusan state: Ishikawa zip: 924-0865 country: Japan name: HIROYUKI ODA role: PRINCIPAL_INVESTIGATOR facility: Ishikawa Prefectural Central Hospital status: NOT_YET_RECRUITING city: Kanazawa state: Ishikawa zip: 920-8530 country: Japan name: Kenji Miwa role: PRINCIPAL_INVESTIGATOR lat: 36.6 lon: 136.61667 facility: National Hospital Organization Kanazawa Medical Center status: RECRUITING city: Kanazawa state: Ishikawa zip: 920-8650 country: Japan name: Takahiro Saeki role: PRINCIPAL_INVESTIGATOR lat: 36.6 lon: 136.61667 facility: Komatsu Municipal Hospital status: NOT_YET_RECRUITING city: Komatsu state: Ishikawa zip: 923-8560 country: Japan name: Toshinori Higashikata role: PRINCIPAL_INVESTIGATOR lat: 36.40263 lon: 136.45088 facility: Kanazawa Medical University Hospital status: RECRUITING city: Uchinada state: Ishikawa zip: 920-0293 country: Japan name: Kouji Kajinami role: PRINCIPAL_INVESTIGATOR facility: Iwate Prefectural Central Hospital status: RECRUITING city: Morioka state: Iwate zip: 020-0066 country: Japan name: Akihiro Nakamura role: PRINCIPAL_INVESTIGATOR lat: 39.7 lon: 141.15 facility: Kagawa Prefectural Central Hospital status: NOT_YET_RECRUITING city: Takamatsu state: Kagawa zip: 760-8557 country: Japan name: Masayuki Doi role: PRINCIPAL_INVESTIGATOR lat: 34.33333 lon: 134.05 facility: Tokai University Hospital- Isehara Campus status: NOT_YET_RECRUITING city: Isehara state: Kanagawa zip: 259-1193 country: Japan name: Tsutomu Murakami role: PRINCIPAL_INVESTIGATOR lat: 35.39932 lon: 139.31019 facility: Takai Internal Medicine Clinic status: RECRUITING city: Kamakura-shi state: Kanagawa zip: 247-0056 country: Japan name: Masahiko Takai role: PRINCIPAL_INVESTIGATOR lat: 35.30889 lon: 139.55028 facility: Shonan Oiso Hospital status: RECRUITING city: Naka-gun state: Kanagawa zip: 259-0114 country: Japan name: Saeko Takahashi role: PRINCIPAL_INVESTIGATOR lat: 36.05 lon: 140.16667 facility: Kitasato University Hospital status: NOT_YET_RECRUITING city: Sagamihara state: Kanagawa zip: 252-0375 country: Japan name: Junya Ako role: PRINCIPAL_INVESTIGATOR lat: 35.54899 lon: 139.26064 facility: Saiseikai Yokohamashi Tobu Hospital status: NOT_YET_RECRUITING city: Yokohama state: Kanagawa zip: 230-8765 country: Japan name: Takamasa Ichijo role: PRINCIPAL_INVESTIGATOR lat: 35.43333 lon: 139.65 facility: Yokosukakyosai status: NOT_YET_RECRUITING city: Yokosuka state: Kanagawa zip: 238-8558 country: Japan name: Keiichi Hishikari role: PRINCIPAL_INVESTIGATOR lat: 35.28361 lon: 139.66722 facility: Osaki Citizen Hospital - Furukawahonami status: NOT_YET_RECRUITING city: Ōsaki state: Miyagi zip: 989-6183 country: Japan name: Junpei Yamamoto role: PRINCIPAL_INVESTIGATOR facility: Miyakonojo Medical Association Hospital - Tarobocho status: RECRUITING city: Miyakonojo state: Miyazaki zip: 885-0002 country: Japan name: Hironao Iwakiri role: PRINCIPAL_INVESTIGATOR lat: 31.73333 lon: 131.06667 facility: Aizawa Hospital status: NOT_YET_RECRUITING city: Matsumoto state: Nagano zip: 390-8510 country: Japan name: Koh Yamashita role: PRINCIPAL_INVESTIGATOR lat: 36.23333 lon: 137.96667 facility: National Hospital Organization Shinshu Ueda Medical Center status: NOT_YET_RECRUITING city: Ueda state: Nagano zip: 386-8610 country: Japan name: Yasufumi Takahashi role: PRINCIPAL_INVESTIGATOR lat: 36.40265 lon: 138.28161 facility: Tachikawa Medical Center status: NOT_YET_RECRUITING city: Nagaoka state: Niigata zip: 940-8621 country: Japan name: Koichi Fuse role: PRINCIPAL_INVESTIGATOR lat: 37.45 lon: 138.85 facility: Kurashiki Central Hospital status: NOT_YET_RECRUITING city: Kurashiki state: Okayama zip: 710-8602 country: Japan name: Kazushige Kadota role: PRINCIPAL_INVESTIGATOR lat: 34.58333 lon: 133.76667 facility: Rinku General Medical Center status: RECRUITING city: Izumisano state: Osaka zip: 598-8577 country: Japan name: Daisaku Masuda role: PRINCIPAL_INVESTIGATOR lat: 34.41663 lon: 135.31667 facility: Medical Corporation Heishinkai OCROM Clinic status: RECRUITING city: Suita-shi state: Osaka zip: 565-0853 country: Japan name: Satoshi Inoue role: PRINCIPAL_INVESTIGATOR lat: 34.76143 lon: 135.51567 facility: National Cerebral and Cardiovascular Center status: NOT_YET_RECRUITING city: Suita state: Osaka zip: 564-8565 country: Japan name: Yu Kataoka role: PRINCIPAL_INVESTIGATOR lat: 34.76143 lon: 135.51567 facility: Osaka Medical and Pharmaceutical University Hospital status: NOT_YET_RECRUITING city: Takatsuki state: Osaka zip: 569-8686 country: Japan name: Masaaki Hoshiga role: PRINCIPAL_INVESTIGATOR lat: 34.84833 lon: 135.61678 facility: Shizuoka Medical Center status: NOT_YET_RECRUITING city: Sunto-gun state: Shizuoka zip: 411-8611 country: Japan name: Jun Tanabe role: PRINCIPAL_INVESTIGATOR facility: International University of Health and Welfare Hospital status: NOT_YET_RECRUITING city: Nasushiobara state: Tochigi zip: 329-2763 country: Japan name: Morihiko Takeda role: PRINCIPAL_INVESTIGATOR lat: 36.97817 lon: 140.03054 facility: The Institute for Adult Disease, Asahi Life Foundation status: RECRUITING city: Chuo-ku state: Tokyo zip: 103-0002 country: Japan name: Yukiko Onishi role: PRINCIPAL_INVESTIGATOR lat: 35.57779 lon: 139.71685 facility: Fukuwa Clinic status: RECRUITING city: Chuo-ku state: Tokyo zip: 104-0031 country: Japan name: Yasushi Fukushima role: PRINCIPAL_INVESTIGATOR lat: 35.57779 lon: 139.71685 facility: National Hospital Organization Tokyo Medical Center status: NOT_YET_RECRUITING city: Meguro-ku state: Tokyo zip: 152-8902 country: Japan name: Kojiro Tanimoto role: PRINCIPAL_INVESTIGATOR lat: 42.12755 lon: 143.31736 facility: Nogata Clinic status: RECRUITING city: Nakano-ku state: Tokyo zip: 165-0027 country: Japan name: Shinji Wakui role: PRINCIPAL_INVESTIGATOR lat: 36.75 lon: 138.36667 facility: Medical Corporation Sato Medical clinic status: NOT_YET_RECRUITING city: Ootaku state: Tokyo zip: 143-0015 country: Japan name: Nobuyuki Sato role: PRINCIPAL_INVESTIGATOR facility: Heishinkai Medical Group ToCROM Clinic status: RECRUITING city: Shinjuku-ku state: Tokyo zip: 160-0008 country: Japan name: Osamu Matsuoka role: PRINCIPAL_INVESTIGATOR lat: 35.2946 lon: 139.57059 facility: Center Hospital of the National Center for Global Health and Medicine status: NOT_YET_RECRUITING city: Shinjyuku-ku state: Tokyo zip: 162-8655 country: Japan name: Yukio Hiroi role: PRINCIPAL_INVESTIGATOR facility: Sekino Hospital status: RECRUITING city: Toshimaku state: Tokyo zip: 171-0014 country: Japan name: Hisakuni Sekino role: PRINCIPAL_INVESTIGATOR facility: Toyama University Hospital status: NOT_YET_RECRUITING city: Toyoma state: Toyama zip: 930-0194 country: Japan name: Hiroshi Ueno role: PRINCIPAL_INVESTIGATOR facility: Tokuyama Central Hospital status: NOT_YET_RECRUITING city: Shunan state: Yamaguchi zip: 745-8522 country: Japan name: Takatoshi Wakeyama role: PRINCIPAL_INVESTIGATOR lat: 34.08053 lon: 131.82564 facility: University of Yamanashi Hospital status: NOT_YET_RECRUITING city: Chuo state: Yamanashi zip: 409-3898 country: Japan name: Takamitsu Nakamura role: PRINCIPAL_INVESTIGATOR lat: 35.57779 lon: 139.71685 facility: Fukuoka Wajiro Hospital status: NOT_YET_RECRUITING city: Fukuoka zip: 811-0213 country: Japan name: Takeshi Serikawa role: PRINCIPAL_INVESTIGATOR lat: 33.6 lon: 130.41667 facility: Tenyoukai Chuo Clinic status: RECRUITING city: Kagoshima zip: 892-0822 country: Japan name: Nobuhiko Atsuchi role: PRINCIPAL_INVESTIGATOR lat: 31.56667 lon: 130.55 facility: Jinnouchi Hospital status: RECRUITING city: Kumamoto zip: 862-0976 country: Japan name: Hideaki Jinnouchi role: PRINCIPAL_INVESTIGATOR lat: 32.80589 lon: 130.69182 facility: Rakuwakai Marutamachi Hospital status: RECRUITING city: Kyoto zip: 604-8401 country: Japan name: Shinichiro Yamaguchi role: PRINCIPAL_INVESTIGATOR lat: 35.02107 lon: 135.75385 facility: Rakuwakai Otowa Hospital status: RECRUITING city: Kyoto zip: 607-8062 country: Japan name: Hirokazu Yokoi role: PRINCIPAL_INVESTIGATOR lat: 35.02107 lon: 135.75385 facility: Miyazaki Medical Association Hospital status: RECRUITING city: Miyazaki zip: 880-2102 country: Japan name: Yoshisato Shibata role: PRINCIPAL_INVESTIGATOR lat: 31.91667 lon: 131.41667 facility: Okayama City General Medical Center Okayama City Hospital status: RECRUITING city: Okayama zip: 700-8557 country: Japan name: Yusuke Kawai role: PRINCIPAL_INVESTIGATOR lat: 34.65 lon: 133.93333 facility: National Hospital Organization Okayama Medical Center status: NOT_YET_RECRUITING city: Okayama zip: 701-1192 country: Japan name: Atsuyuki Watanabe role: PRINCIPAL_INVESTIGATOR lat: 34.65 lon: 133.93333 facility: National Hospital Organization - Osaka National Hospital - Institute For Clinical Research status: NOT_YET_RECRUITING city: Osaka zip: 540-0006 country: Japan name: Yasunori Ueda role: PRINCIPAL_INVESTIGATOR lat: 34.69374 lon: 135.50218 facility: Osaka Police Hospital status: RECRUITING city: Osaka zip: 543-0035 country: Japan name: Yoshiharu Higuchi role: PRINCIPAL_INVESTIGATOR lat: 34.69374 lon: 135.50218 facility: Kansai Electric Power Hospital status: NOT_YET_RECRUITING city: Osaka zip: 553-0003 country: Japan name: Yoshiyuki Initials Hamamoto role: PRINCIPAL_INVESTIGATOR lat: 34.69374 lon: 135.50218 facility: Osaka General Medical Center status: NOT_YET_RECRUITING city: Osaka zip: 558-8558 country: Japan name: Takahisa Yamada role: PRINCIPAL_INVESTIGATOR lat: 34.69374 lon: 135.50218 facility: Saga University Hospital status: NOT_YET_RECRUITING city: Saga zip: 849-8501 country: Japan name: Koichi Node role: PRINCIPAL_INVESTIGATOR lat: 33.23333 lon: 130.3 facility: Sanai Hospital - Saitama status: NOT_YET_RECRUITING city: Saitama zip: 338-0837 country: Japan name: Akitaka Nakata role: PRINCIPAL_INVESTIGATOR lat: 35.90807 lon: 139.65657 facility: Gachon University Gil Medical Center status: RECRUITING city: Namdong-gu state: Incheon-gwangyeoksi [Incheon] zip: 21565 country: Korea, Republic of name: Youngwoo Jang role: PRINCIPAL_INVESTIGATOR facility: Yonsei University-Wonju Severance Christian Hospital status: RECRUITING city: Wonju state: Kang-won-do zip: 26426 country: Korea, Republic of name: Byung-Su Yoo role: PRINCIPAL_INVESTIGATOR lat: 37.35139 lon: 127.94528 facility: Chonnam National University Hospital status: RECRUITING city: Gwangju-si state: Kwangju-Kwangyǒkshi zip: 61469 country: Korea, Republic of name: Youngkeun Ahn role: PRINCIPAL_INVESTIGATOR lat: 35.15472 lon: 126.91556 facility: The Catholic University of Korea, Bucheon St. Mary's Hospital status: RECRUITING city: Bucheon-si state: Kyǒnggi-do zip: 14647 country: Korea, Republic of name: SoonJib Yoo role: PRINCIPAL_INVESTIGATOR lat: 37.49889 lon: 126.78306 facility: Seoul National University Bundang Hospital status: NOT_YET_RECRUITING city: Seongnam state: Kyǒnggi-do zip: 13620 country: Korea, Republic of name: IN-HO CHAE role: PRINCIPAL_INVESTIGATOR lat: 37.43861 lon: 127.13778 facility: Seoul National University Bundang Hospital status: NOT_YET_RECRUITING city: Seongnam state: Kyǒnggi-do zip: 13620 country: Korea, Republic of name: Sung Hee Choi role: PRINCIPAL_INVESTIGATOR lat: 37.43861 lon: 127.13778 facility: Sejong General Hospital status: NOT_YET_RECRUITING city: Sosa-gu state: Kyǒnggi-do zip: 14754 country: Korea, Republic of name: Hyun-Jong Lee role: PRINCIPAL_INVESTIGATOR facility: The Catholic University Of Korea St. Vincent's Hospital status: NOT_YET_RECRUITING city: Suwon-si state: Kyǒnggi-do zip: 16247 country: Korea, Republic of name: Seung Hyun Ko role: PRINCIPAL_INVESTIGATOR lat: 37.29111 lon: 127.00889 facility: Boramae Medical Center status: NOT_YET_RECRUITING city: Dongjak-gu state: Seoul-teukbyeolsi [Seoul] zip: 07061 country: Korea, Republic of name: Min Kyong Moon role: PRINCIPAL_INVESTIGATOR facility: Boramae Medical Center status: NOT_YET_RECRUITING city: Dongjak-gu state: Seoul-teukbyeolsi [Seoul] zip: 07061 country: Korea, Republic of name: SANG-HYUN KIM role: PRINCIPAL_INVESTIGATOR facility: Kyung Hee University Hospital status: NOT_YET_RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 02447 country: Korea, Republic of name: Weon Kim role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: Korea University Anam Hospital status: RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 02841 country: Korea, Republic of name: Soon Jun Hong role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: Seoul National University Hospital status: NOT_YET_RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 03080 country: Korea, Republic of name: Hyun-Jae Kang role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: Kangbuk Samsung Hospital status: RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 03181 country: Korea, Republic of name: ByungJin Kim role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: Severance Hospital, Yonsei University Health System status: NOT_YET_RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 03722 country: Korea, Republic of name: Sang-Hak Lee role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: Asan Medical Center status: NOT_YET_RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 05505 country: Korea, Republic of name: KI HOON HAN role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: Asan Medical Center status: NOT_YET_RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 05505 country: Korea, Republic of name: WOO JE LEE role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: The Catholic Univ. of Korea Seoul St. Mary's Hospital status: NOT_YET_RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 06591 country: Korea, Republic of name: Kiyuk Chang role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: The Catholic Univ. of Korea Seoul St. Mary's Hospital status: NOT_YET_RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 06591 country: Korea, Republic of name: Seung-Hwan Lee role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: Kyung Hee University Hospital at Gangdong status: RECRUITING city: Seoul state: Seoul-teukbyeolsi [Seoul] zip: 134-090 country: Korea, Republic of name: In-Kyung Jeong role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 facility: Daegu Catholic University Medical Center status: NOT_YET_RECRUITING city: Daegu state: Taegu-Kwangyǒkshi zip: 42472 country: Korea, Republic of name: SEUNGPYO HONG role: PRINCIPAL_INVESTIGATOR lat: 35.87028 lon: 128.59111 facility: Keimyung University Dongsan Hospital status: RECRUITING city: Daegu state: Taegu-Kwangyǒkshi zip: 42601 country: Korea, Republic of name: Seung-Ho Hur role: PRINCIPAL_INVESTIGATOR lat: 35.87028 lon: 128.59111 facility: Eulji University Hospital status: NOT_YET_RECRUITING city: Daejeon state: Taejǒn-Kwangyǒkshi zip: 01830 country: Korea, Republic of name: Jun-Hwa Hong role: PRINCIPAL_INVESTIGATOR lat: 36.32139 lon: 127.41972 facility: Ulsan University Hospital status: NOT_YET_RECRUITING city: Ulsan state: Ulsan-Kwangyǒkshi zip: 44033 country: Korea, Republic of name: GYUNGMIN PARK role: PRINCIPAL_INVESTIGATOR lat: 35.53722 lon: 129.31667 facility: Centro de Investigacion Cardiovascular y Metabólica status: NOT_YET_RECRUITING city: Tijuana state: Baja California zip: 22500 country: Mexico name: Pedro Fajardo Campos role: PRINCIPAL_INVESTIGATOR lat: 32.5027 lon: -117.00371 facility: Centro Médico Nacional Siglo XXI status: NOT_YET_RECRUITING city: Ciudad de México state: Distrito Federal zip: 06720 country: Mexico name: Juan Ivey Miranda role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: RM Pharma Specialists status: NOT_YET_RECRUITING city: Mexico City state: Distrito Federal zip: 03100 country: Mexico name: Mariana Zolandi Crespo role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: Clínicos Asociados BOCM status: NOT_YET_RECRUITING city: Mexico City state: Distrito Federal zip: 03300 country: Mexico name: Israel Olvera-Alvarez role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: Grupo Medico Camino Sc status: NOT_YET_RECRUITING city: Mexico City state: Distrito Federal zip: 03310 country: Mexico name: JORGE SIERRA role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: Hospital de Jésus, I.A.P. status: NOT_YET_RECRUITING city: Mexico City state: Distrito Federal zip: 06090 country: Mexico name: Efrain Villeda Espinosa role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: Clinica Omega status: NOT_YET_RECRUITING city: Mexico City state: Distrito Federal zip: 06700 country: Mexico name: Jose Hector Sanchez Mijangos role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: Centro Especializado En Diabetes, Obesidad Y Prevencion De Enfermedades Cardiovasculares status: NOT_YET_RECRUITING city: Mexico City state: Distrito Federal zip: 11650 country: Mexico name: Melchor Alpizar Salazar role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: ProcliniQ Investigación Clínica SA de CV status: NOT_YET_RECRUITING city: Mexico City state: Distrito Federal zip: 14050 country: Mexico name: Mauricio Lopez Meneses role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran status: NOT_YET_RECRUITING city: Mexico City state: Distrito Federal zip: 14080 country: Mexico name: Carlos Aguilar Salinas role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: Clinstile, S.A. de C.V. status: NOT_YET_RECRUITING city: Mexico state: Distrito Federal zip: 06700 country: Mexico name: Vicente Eduardo Ruiz Ruiz role: PRINCIPAL_INVESTIGATOR lat: 19.42847 lon: -99.12766 facility: Medimanage Research status: NOT_YET_RECRUITING city: Tlalpan state: Distrito Federal zip: 14050 country: Mexico name: Nydia Avila-Vanzzini role: PRINCIPAL_INVESTIGATOR lat: 19.29513 lon: -99.16206 facility: Instituto Cardiovascular de León S.C. status: NOT_YET_RECRUITING city: León state: Guanajuato zip: 37520 country: Mexico name: Luis Adolfo Venegas Carrillo role: PRINCIPAL_INVESTIGATOR lat: 21.12908 lon: -101.67374 facility: Instituto Jalisciense de Investigacion en Diabetes y Obesidad status: NOT_YET_RECRUITING city: Guadalajara state: Jalisco zip: 04460 country: Mexico name: Guillermo Gonzalez Galvez role: PRINCIPAL_INVESTIGATOR lat: 20.66682 lon: -103.39182 facility: Diseno y Planeacion en Investigacion Medica status: NOT_YET_RECRUITING city: Guadalajara state: Jalisco zip: 44130 country: Mexico name: Cesar Calvo role: PRINCIPAL_INVESTIGATOR lat: 20.66682 lon: -103.39182 facility: Centro de Investigacion Medica Integral status: NOT_YET_RECRUITING city: Guadalajara state: Jalisco zip: 44160 country: Mexico name: Carlos Alejandro Stobschinski de Alba role: PRINCIPAL_INVESTIGATOR lat: 20.66682 lon: -103.39182 facility: Unidad de Investigación Clínica y Atención Médica HEPA status: NOT_YET_RECRUITING city: Guadalajara state: Jalisco zip: 44670 country: Mexico name: Marisol Herrera Marmolejo role: PRINCIPAL_INVESTIGATOR lat: 20.66682 lon: -103.39182 facility: Virgen Cardiovascular Research SC status: NOT_YET_RECRUITING city: Guadalajara state: Jalisco zip: 44670 country: Mexico name: Luis Ramon Virgen Carrillo role: PRINCIPAL_INVESTIGATOR lat: 20.66682 lon: -103.39182 facility: CINVEC Medica status: NOT_YET_RECRUITING city: Guadalajara state: Jalisco zip: 44690 country: Mexico name: Alejandro Avila Carrillo role: PRINCIPAL_INVESTIGATOR lat: 20.66682 lon: -103.39182 facility: Clinica de Enfermedades Crónicas y de Procedimientos Especiales status: NOT_YET_RECRUITING city: Morelia state: Michoacán zip: 58249 country: Mexico name: Helios Vega role: PRINCIPAL_INVESTIGATOR lat: 19.70078 lon: -101.18443 facility: Instituto de Diabetes, Obesidad y Nutricion status: NOT_YET_RECRUITING city: Cuernavaca state: Morelos zip: 62250 country: Mexico name: Leobardo Sauque Reyna role: PRINCIPAL_INVESTIGATOR lat: 18.9261 lon: -99.23075 facility: CHRISTUS Centro de Excelencia en Investigación (Norte) status: NOT_YET_RECRUITING city: General Escobedo state: Nuevo León zip: 66055 country: Mexico name: Ivan Rosendo Salinas Cavazos role: PRINCIPAL_INVESTIGATOR lat: 25.79698 lon: -100.31791 facility: Accelerium Clinical Research status: NOT_YET_RECRUITING city: Monterrey state: Nuevo León zip: 64000 country: Mexico name: Eduardo Roderick Elizondo Moreno role: PRINCIPAL_INVESTIGATOR lat: 25.67507 lon: -100.31847 facility: Cardiolink Clin Trials status: NOT_YET_RECRUITING city: Monterrey state: Nuevo León zip: 64060 country: Mexico name: Elías García role: PRINCIPAL_INVESTIGATOR lat: 25.67507 lon: -100.31847 facility: Hospital Universitario "Dr. Jose Eleuterio Gonzalez" status: NOT_YET_RECRUITING city: Monterrey state: Nuevo León zip: 64460 country: Mexico name: RAMIRO FLORES-RAMIREZ role: PRINCIPAL_INVESTIGATOR lat: 25.67507 lon: -100.31847 facility: Hospital Universitario "Dr. Jose Eleuterio Gonzalez" status: NOT_YET_RECRUITING city: Monterrey state: Nuevo León zip: 64460 country: Mexico name: Jose Gerardo Gonzalez Gonzalez role: PRINCIPAL_INVESTIGATOR lat: 25.67507 lon: -100.31847 facility: Unidad biomedica avanzada monterrey status: NOT_YET_RECRUITING city: Monterrey state: Nuevo León zip: 64460 country: Mexico name: Raymundo Garcia Reza role: PRINCIPAL_INVESTIGATOR lat: 25.67507 lon: -100.31847 facility: Clínica García Flores SC status: NOT_YET_RECRUITING city: Monterrey state: Nuevo León zip: 64610 country: Mexico name: Pedro Alberto Garcia role: PRINCIPAL_INVESTIGATOR lat: 25.67507 lon: -100.31847 facility: Centro de investigación y control metabólico status: NOT_YET_RECRUITING city: Monterrey state: Nuevo León zip: 66465 country: Mexico name: Víctor Castelán Vargas role: PRINCIPAL_INVESTIGATOR lat: 25.67507 lon: -100.31847 facility: Servicios Integrales Nova de Monterrey S.A. de C.V. status: NOT_YET_RECRUITING city: San Nicolas de los Garza state: Nuevo León zip: 66450 country: Mexico name: Maria Elena Romero-Ibarguengoitia role: PRINCIPAL_INVESTIGATOR lat: 25.74167 lon: -100.30222 facility: Centro de Investigacion Clinica de Oaxaca status: NOT_YET_RECRUITING city: Oaxaca de Juarez state: Oaxaca zip: 68020 country: Mexico name: Jesus Antonio Perez Ríos role: PRINCIPAL_INVESTIGATOR lat: 17.06542 lon: -96.72365 facility: Centro Para El Desarrollo de La Medicina Y de Asistencia Medica Especializada S.C. status: NOT_YET_RECRUITING city: Culiacan state: Sinaloa zip: 80230 country: Mexico name: Manuel Odin de los Rios Ibarra role: PRINCIPAL_INVESTIGATOR lat: 24.79032 lon: -107.38782 facility: Investigación Médica Sonora, S.C. status: NOT_YET_RECRUITING city: Hermosillo state: Sonora zip: 83270 country: Mexico name: Diego Espinoza Peralta role: PRINCIPAL_INVESTIGATOR lat: 29.1026 lon: -110.97732 facility: Meander Medisch Centrum status: NOT_YET_RECRUITING city: Amersfoort state: Utrecht zip: 3813 TZ country: Mexico name: Arend Mosterd role: PRINCIPAL_INVESTIGATOR facility: Hospital Angeles Xalapa status: NOT_YET_RECRUITING city: Xalapa state: Veracruz zip: 91193 country: Mexico name: Gustavo Mendez Machado role: PRINCIPAL_INVESTIGATOR lat: 19.53124 lon: -96.91589 facility: Medical Care and Research SA de CV status: NOT_YET_RECRUITING city: Merida state: Yucatán zip: 97070 country: Mexico name: Christian Gonzalez role: PRINCIPAL_INVESTIGATOR lat: 20.97537 lon: -89.61696 facility: Groene Hart Ziekenhuis status: NOT_YET_RECRUITING city: Gouda state: Zuid-Holland zip: 2803HH country: Mexico name: Stefan Koudstaal role: PRINCIPAL_INVESTIGATOR facility: Centro de Investigación Cardiometabólica de Aguascalientes status: NOT_YET_RECRUITING city: Aguascalientes zip: 20230 country: Mexico name: Enrique Cuitlahuac Morales-Villegas role: PRINCIPAL_INVESTIGATOR lat: 21.88234 lon: -102.28259 facility: Fundación Cardiovascular de Aguascalientes A.C. status: NOT_YET_RECRUITING city: Aguascalientes zip: 20230 country: Mexico name: Edmundo Alfredo Bayram Llamas role: PRINCIPAL_INVESTIGATOR lat: 21.88234 lon: -102.28259 facility: Hospital Cardiologica Aguescalientes status: NOT_YET_RECRUITING city: Aguascalientes zip: 20230 country: Mexico name: Guillermo Antonio Llamas Esperon role: PRINCIPAL_INVESTIGATOR lat: 21.88234 lon: -102.28259 facility: Enclifar Ensayos Clínicos Farmacológicos Sc status: NOT_YET_RECRUITING city: Chihuahua zip: 31110 country: Mexico name: Luis Alejandro Nevarez role: PRINCIPAL_INVESTIGATOR lat: 28.63528 lon: -106.08889 facility: Lahoja. Asociacion Para La Investigacion Y La Farmacovigilancia status: NOT_YET_RECRUITING city: Durango zip: 34000 country: Mexico name: Juan Carlos Núñez Fragoso role: PRINCIPAL_INVESTIGATOR lat: 24.02032 lon: -104.65756 facility: Centro de Estudios Clínicos de Querétaro (CECLIQ) status: NOT_YET_RECRUITING city: Querétaro zip: 76000 country: Mexico name: Marco Antonio Alcocer Gamba role: PRINCIPAL_INVESTIGATOR facility: PanAmerican Clinical Research - Querétaro - Avenida Antea status: NOT_YET_RECRUITING city: Querétaro zip: 76100 country: Mexico name: Juan Villagordoa Mesa role: PRINCIPAL_INVESTIGATOR facility: Centro de Atención e Investigación Cardiovascular del Potosí status: NOT_YET_RECRUITING city: San Luis Potosí zip: 78200 country: Mexico name: José Rivera Arellano role: PRINCIPAL_INVESTIGATOR lat: 22.14982 lon: -100.97916 facility: Universitair Medisch Centrum Utrecht status: NOT_YET_RECRUITING city: Utrecht zip: 3584 CX country: Mexico name: Jannick Dorresteijn role: PRINCIPAL_INVESTIGATOR facility: Instituto Veracruzano en Investigación Clínica S.C. status: NOT_YET_RECRUITING city: Veracruz zip: 91851 country: Mexico name: Rosa Isela Luna Ceballos role: PRINCIPAL_INVESTIGATOR lat: 19.18095 lon: -96.1429 facility: Medische Centrum Leeuwarden status: NOT_YET_RECRUITING city: Leeuwarden state: Fryslân zip: 8934 AD country: Netherlands name: T. Vossenberg role: PRINCIPAL_INVESTIGATOR lat: 53.20139 lon: 5.80859 facility: Antonius Ziekenhuis, locatie D&A Research and Genetics status: NOT_YET_RECRUITING city: Sneek state: Fryslân zip: 8601 ZR country: Netherlands name: Renee Duitman role: PRINCIPAL_INVESTIGATOR lat: 53.03297 lon: 5.6589 facility: Gelre Ziekenhuis status: NOT_YET_RECRUITING city: Apeldoorn state: Gelderland zip: 7334 DZ country: Netherlands name: Bjorn Groenemeijer role: PRINCIPAL_INVESTIGATOR lat: 52.21 lon: 5.96944 facility: Slingeland Ziekenhuis status: NOT_YET_RECRUITING city: Doetinchem state: Gelderland zip: 7009 BL country: Netherlands name: Jeroen Jaspers Focks role: PRINCIPAL_INVESTIGATOR lat: 51.965 lon: 6.28889 facility: Ziekenhuis Gelderse Vallei status: NOT_YET_RECRUITING city: Ede state: Gelderland zip: 6716 RP country: Netherlands name: Thomas Oosterhof role: PRINCIPAL_INVESTIGATOR lat: 52.03333 lon: 5.65833 facility: Ziekenhuis St. Jansdal status: NOT_YET_RECRUITING city: Harderwijk state: Gelderland zip: 3844 DG country: Netherlands name: Marc van der Zee role: PRINCIPAL_INVESTIGATOR lat: 52.34167 lon: 5.62083 facility: Radboudumc status: NOT_YET_RECRUITING city: Nijmegen state: Gelderland zip: 6525 GA country: Netherlands name: Saloua El Messaoudi role: PRINCIPAL_INVESTIGATOR lat: 51.8425 lon: 5.85278 facility: VieCuri Medisch Centrum, locatie Venlo status: NOT_YET_RECRUITING city: Venlo state: Limburg zip: 5912 BL country: Netherlands name: Wouter Remkes role: PRINCIPAL_INVESTIGATOR lat: 51.37 lon: 6.16806 facility: Jeroen Bosch ziekenhuis status: NOT_YET_RECRUITING city: Den Bosch state: Noord-Brabant zip: 5223 GZ country: Netherlands name: Martijn van Eck role: PRINCIPAL_INVESTIGATOR lat: 51.27 lon: 5.59167 facility: Catharina Ziekenhuis status: NOT_YET_RECRUITING city: Eindhoven state: Noord-Brabant zip: 5623 EJ country: Netherlands name: Guus Brueren role: PRINCIPAL_INVESTIGATOR lat: 51.44083 lon: 5.47778 facility: Bravis Ziekenhuis, locatie Roosendaal status: NOT_YET_RECRUITING city: Roosendaal state: Noord-Brabant zip: 4708 AE country: Netherlands name: Reinhart Dorman role: PRINCIPAL_INVESTIGATOR lat: 51.53083 lon: 4.46528 facility: ETZ TweeSteden status: NOT_YET_RECRUITING city: Tilburg state: Noord-Brabant zip: 5042 AD country: Netherlands name: Pascalle Monraats role: PRINCIPAL_INVESTIGATOR lat: 51.55551 lon: 5.0913 facility: Maxima Medisch Centrum, locatie Veldhoven status: NOT_YET_RECRUITING city: Veldhoven state: Noord-Brabant zip: 5504 DB country: Netherlands name: Sabine Eijsbouts role: PRINCIPAL_INVESTIGATOR lat: 51.41833 lon: 5.40278 facility: Onze Lieve Vrouwe Gasthuis status: NOT_YET_RECRUITING city: Amsterdam state: Noord-Holland zip: 1091 AC country: Netherlands name: Ton Slagboom role: PRINCIPAL_INVESTIGATOR lat: 52.37403 lon: 4.88969 facility: Amsterdam UMC, locatie AMC status: NOT_YET_RECRUITING city: Amsterdam state: Noord-Holland zip: 1105 AZ country: Netherlands name: Erik Stroes role: PRINCIPAL_INVESTIGATOR lat: 52.37403 lon: 4.88969 facility: Rode Kruis Ziekenhuis status: NOT_YET_RECRUITING city: Beverwijk state: Noord-Holland zip: 1942 LE country: Netherlands name: Iris Westendorp role: PRINCIPAL_INVESTIGATOR lat: 52.48333 lon: 4.65694 facility: Spaarne Gasthuis, Haarlem Zuid status: NOT_YET_RECRUITING city: Haarlem state: Noord-Holland zip: 2035 RC country: Netherlands name: Aaf Kuijper role: PRINCIPAL_INVESTIGATOR lat: 52.38084 lon: 4.63683 facility: Tergooiziekenhuizen, locatie Hilversum status: NOT_YET_RECRUITING city: Hilversum state: Noord-Holland zip: 1212 VG country: Netherlands name: Pieter Kamphuisen role: SUB_INVESTIGATOR lat: 52.22333 lon: 5.17639 facility: Zaans Medisch Centrum status: NOT_YET_RECRUITING city: Zaandam state: Noord-Holland zip: 1502 DV country: Netherlands name: P.A. Dijkmans role: PRINCIPAL_INVESTIGATOR lat: 52.43854 lon: 4.82643 facility: Deventer Ziekenhuis status: NOT_YET_RECRUITING city: Deventer state: Overijssel zip: 7416 SE country: Netherlands name: Elsemiek Engbers role: PRINCIPAL_INVESTIGATOR lat: 52.255 lon: 6.16389 facility: Saxenburgh Medisch Centrum status: NOT_YET_RECRUITING city: Hardenberg state: Overijssel zip: 7772 SE country: Netherlands name: Bas Bemmel role: PRINCIPAL_INVESTIGATOR lat: 52.57583 lon: 6.61944 facility: Admiraal de Ruyter Ziekenhuis, locatie Goes status: NOT_YET_RECRUITING city: Goes state: Zeeland zip: 4462 RA country: Netherlands name: Fesile Basar role: PRINCIPAL_INVESTIGATOR lat: 51.50417 lon: 3.88889 facility: Reinier de Graaf Ziekenhuis, locatie Delft status: NOT_YET_RECRUITING city: Delft state: Zuid-Holland zip: 2625 AD country: Netherlands name: Jan Constandse role: PRINCIPAL_INVESTIGATOR lat: 52.00667 lon: 4.35556 facility: Haga Ziekenhuis locatie Leyweg status: NOT_YET_RECRUITING city: Den Haag state: Zuid-Holland zip: 2545 AA country: Netherlands name: Albert Mairuhu role: PRINCIPAL_INVESTIGATOR lat: 52.07667 lon: 4.29861 facility: Leids Universitair Medisch Centrum status: NOT_YET_RECRUITING city: Leiden state: Zuid-Holland zip: 2333 ZA country: Netherlands name: Wouter Jukema role: PRINCIPAL_INVESTIGATOR lat: 52.15833 lon: 4.49306 facility: Erasmus Medisch Centrum status: NOT_YET_RECRUITING city: Rotterdam state: Zuid-Holland zip: 3015 GD country: Netherlands name: Jeanine Roeters van Lennep role: PRINCIPAL_INVESTIGATOR lat: 51.9225 lon: 4.47917 facility: Ikazia Ziekenhuis status: NOT_YET_RECRUITING city: Rotterdam state: Zuid-Holland zip: 3083 AN country: Netherlands name: Mireille Emans role: PRINCIPAL_INVESTIGATOR lat: 51.9225 lon: 4.47917 facility: General Practitioners Research Institute (GPRI) status: NOT_YET_RECRUITING city: Groningen zip: 9713 GH country: Netherlands name: Janwillem WH Kocks role: PRINCIPAL_INVESTIGATOR lat: 53.21917 lon: 6.56667 facility: Martini Ziekenhuis status: NOT_YET_RECRUITING city: Groningen zip: 9728 NT country: Netherlands name: G.L. Bartels role: PRINCIPAL_INVESTIGATOR lat: 53.21917 lon: 6.56667 facility: 4 Wojskowy Szpital Kliniczny z Polikliniką SPZOZ status: NOT_YET_RECRUITING city: Wrocław state: Dolnośląskie zip: 50-981 country: Poland name: Bartosz Krakowiak role: PRINCIPAL_INVESTIGATOR lat: 51.1 lon: 17.03333 facility: NZOZ Centurm Medyczne SERAFIN-MED status: NOT_YET_RECRUITING city: Zarow state: Dolnośląskie zip: 58-130 country: Poland name: Ryszard Serafin role: PRINCIPAL_INVESTIGATOR lat: 50.94116 lon: 16.49466 facility: NZOZ Centrum Medyczne KERmed status: NOT_YET_RECRUITING city: Bydgoszcz state: Kujawsko-pomorskie zip: 85-231 country: Poland name: Tomasz Lugowski role: PRINCIPAL_INVESTIGATOR lat: 53.1235 lon: 18.00762 facility: INTERCOR status: NOT_YET_RECRUITING city: Bydgoszcz state: Kujawsko-pomorskie zip: 85-605 country: Poland name: Grzegorz Grzesk role: PRINCIPAL_INVESTIGATOR lat: 53.1235 lon: 18.00762 facility: Euromedica status: NOT_YET_RECRUITING city: Grudziadz state: Kujawsko-pomorskie zip: 86-300 country: Poland name: Piotr Kubalski role: PRINCIPAL_INVESTIGATOR lat: 53.48411 lon: 18.75366 facility: 1 Wojskowy Szpital Kliniczny w Lublinie status: NOT_YET_RECRUITING city: Lublin state: Lubelskie zip: 20-043 country: Poland name: Grzegorz Sobieszek role: PRINCIPAL_INVESTIGATOR lat: 51.25 lon: 22.56667 facility: CenterMed Lublin NZOZ status: NOT_YET_RECRUITING city: Lublin state: Lubelskie zip: 20-044 country: Poland name: Grzegorz Drelich role: PRINCIPAL_INVESTIGATOR lat: 51.25 lon: 22.56667 facility: Private Practice - Dr. Michał Tomaszewski status: NOT_YET_RECRUITING city: Lublin state: Lubelskie zip: 20-068 country: Poland name: Michal Tomaszewski role: PRINCIPAL_INVESTIGATOR lat: 51.25 lon: 22.56667 facility: Clinical Best Solutions status: NOT_YET_RECRUITING city: Lublin state: Lubelskie zip: 20-078 country: Poland name: MARZENA JANIK-PALAZZOLO role: PRINCIPAL_INVESTIGATOR lat: 51.25 lon: 22.56667 facility: Wielospecjalistyczny Szpital Samodzielny Publiczny Zakład Opieki Zdrowotnej w Nowej Soli status: NOT_YET_RECRUITING city: Nowa Sol state: Lubuskie zip: 67-100 country: Poland name: Jaroslaw Hiczkiewicz role: PRINCIPAL_INVESTIGATOR lat: 51.80333 lon: 15.71702 facility: WIP Warsaw IBD Point Profesor Kierkus status: NOT_YET_RECRUITING city: Warsaw state: Mazowieckie zip: 00-728 country: Poland name: Agata Krzesiak-Lodyga role: PRINCIPAL_INVESTIGATOR lat: 52.22977 lon: 21.01178 facility: Balsam Medica status: NOT_YET_RECRUITING city: Warsaw state: Mazowieckie zip: 01-249 country: Poland name: Marcin Grabowski role: PRINCIPAL_INVESTIGATOR lat: 52.22977 lon: 21.01178 facility: Clinical Best Solutions status: NOT_YET_RECRUITING city: Warszawa state: Mazowieckie zip: 00-710 country: Poland name: Joanna Niegowska role: PRINCIPAL_INVESTIGATOR lat: 52.22977 lon: 21.01178 facility: Polsko-Amerykańskie Kliniki Serca PAKS Małopolskie Centrum Sercowo-Naczyniowe status: NOT_YET_RECRUITING city: Chrzanow state: Małopolskie zip: 32-500 country: Poland name: Aleksander Zurakowski role: PRINCIPAL_INVESTIGATOR lat: 50.13546 lon: 19.40203 facility: Centrum Medyczne Linden status: NOT_YET_RECRUITING city: Krakow state: Małopolskie zip: 30-721 country: Poland name: Beata Maria Bobrowska role: PRINCIPAL_INVESTIGATOR lat: 50.06143 lon: 19.93658 facility: NZOZ Diab-Endo-Met status: NOT_YET_RECRUITING city: Krakow state: Małopolskie zip: 31-261 country: Poland name: Magdalena Kwiatkowska role: PRINCIPAL_INVESTIGATOR lat: 50.06143 lon: 19.93658 facility: Centrum Szybkiej Diagnostyki Kardiologicznej "Kardiomed" M. Żabówka E. Żabówka status: NOT_YET_RECRUITING city: Tarnow state: Małopolskie zip: 33-100 country: Poland name: Maciej Stanislaw Zabowka role: PRINCIPAL_INVESTIGATOR lat: 50.01381 lon: 20.98698 facility: Polsko-Amerykańskie Kliniki Serca status: NOT_YET_RECRUITING city: Kedzierzyn-Kozle state: Opolskie zip: 47-200 country: Poland name: Janusz Prokopczuk role: PRINCIPAL_INVESTIGATOR lat: 50.34984 lon: 18.22606 facility: Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu status: NOT_YET_RECRUITING city: Przemysl state: Podkarpackie zip: 37-700 country: Poland name: Lukasz Wisniowski role: PRINCIPAL_INVESTIGATOR lat: 49.78498 lon: 22.76728 facility: Specderm Poznanska status: NOT_YET_RECRUITING city: Bialystok state: Podlaskie zip: 15-375 country: Poland name: Katarzyna Ptaszynska role: PRINCIPAL_INVESTIGATOR lat: 53.13333 lon: 23.16433 facility: Uniwersyteckie Centrum Kliniczne status: NOT_YET_RECRUITING city: Gdańsk state: Pomorskie zip: 80-952 country: Poland name: Agnieszka Mickiewicz role: PRINCIPAL_INVESTIGATOR lat: 54.35205 lon: 18.64637 facility: Centrum Kliniczno-Badawcze status: NOT_YET_RECRUITING city: Elblag state: Warmińsko-mazurskie zip: 82-300 country: Poland name: Bozena Gornikiewicz-Brzezicka role: PRINCIPAL_INVESTIGATOR lat: 54.1522 lon: 19.40884 facility: NZOZ TwojeZdrowie status: NOT_YET_RECRUITING city: Elblag state: Warmińsko-mazurskie zip: 82-300 country: Poland name: Waldemar Bieniek role: PRINCIPAL_INVESTIGATOR lat: 54.1522 lon: 19.40884 facility: Poliklinika Kardiologiczna Serce status: NOT_YET_RECRUITING city: Leszno state: Wielkopolskie zip: 64-100 country: Poland name: Witold Piotrowski role: PRINCIPAL_INVESTIGATOR lat: 51.84034 lon: 16.57494 facility: Centra Medyczne Medyceusz status: NOT_YET_RECRUITING city: Lodz state: Łódzkie zip: 91-053 country: Poland name: Wlodzimierz Kus role: PRINCIPAL_INVESTIGATOR lat: 51.75 lon: 19.46667 facility: Pro Salus Centrum Medyczne status: NOT_YET_RECRUITING city: Lodz state: Łódzkie zip: 91-473 country: Poland name: Marcin Ojrzanowski role: PRINCIPAL_INVESTIGATOR lat: 51.75 lon: 19.46667 facility: Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Lodzi status: NOT_YET_RECRUITING city: Łódź state: Łódzkie zip: 93-513 country: Poland name: Grzegorz Piotrowski role: PRINCIPAL_INVESTIGATOR lat: 51.75 lon: 19.46667 facility: Polsko-Amerykańskie Kliniki Serca II Oddział Kardiologiczny status: NOT_YET_RECRUITING city: Bielsko-Biala state: Śląskie zip: 43-300 country: Poland name: Krzysztof Milewski role: PRINCIPAL_INVESTIGATOR lat: 49.82245 lon: 19.04686 facility: Polsko-Amerykańskie Kliniki Serca status: NOT_YET_RECRUITING city: Dabrowa Gornicza state: Śląskie zip: 41-300 country: Poland name: Katarzyna Szymczyk role: PRINCIPAL_INVESTIGATOR lat: 50.31818 lon: 19.2374 facility: NZOZ Salvia CM status: NOT_YET_RECRUITING city: Katowice state: Śląskie zip: 40-772 country: Poland name: Andrzej Madej role: PRINCIPAL_INVESTIGATOR lat: 50.25841 lon: 19.02754 facility: AKA-MED Centrum status: NOT_YET_RECRUITING city: Ruda Slaska state: Śląskie zip: 41-710 country: Poland name: Janusz Spyra role: PRINCIPAL_INVESTIGATOR lat: 50.2584 lon: 18.85632 facility: Polsko-Amerykańskie Kliniki Serca status: NOT_YET_RECRUITING city: Tychy state: Śląskie zip: 43-100 country: Poland name: Adam Janas role: PRINCIPAL_INVESTIGATOR lat: 50.13717 lon: 18.96641 facility: Advanced Clinical Research, LLC status: RECRUITING city: Bayamón zip: 00959 country: Puerto Rico name: Angel Comulada-Rivera role: PRINCIPAL_INVESTIGATOR lat: 18.39856 lon: -66.15572 facility: GCM Medical Group, PSC - Hato Rey Site status: RECRUITING city: San Juan zip: 00917 country: Puerto Rico name: Gregorio Cortes-Maisonet role: PRINCIPAL_INVESTIGATOR lat: 18.46633 lon: -66.10572 facility: Nicodiab status: NOT_YET_RECRUITING city: Bucharest state: București zip: 010507 country: Romania name: NICOLETA MINDRESCU role: PRINCIPAL_INVESTIGATOR lat: 44.43225 lon: 26.10626 facility: Hightech Medical Services SRL-Centrul pentru Studiul Metabolismului status: RECRUITING city: Bucharest state: București zip: 011053 country: Romania name: Ciprian Constantin role: PRINCIPAL_INVESTIGATOR lat: 44.43225 lon: 26.10626 facility: Centrul Medical NutriLife status: RECRUITING city: Bucharest state: București zip: 013764 country: Romania name: Marlena Pascu role: PRINCIPAL_INVESTIGATOR lat: 44.43225 lon: 26.10626 facility: Centrul Medical Endocrinologie si Diabet Dr. Paveliu status: RECRUITING city: Bucharest state: București zip: 50538 country: Romania name: Fraga Paveliu role: PRINCIPAL_INVESTIGATOR lat: 44.43225 lon: 26.10626 facility: Mat Cord Biomedica S.R.L. status: NOT_YET_RECRUITING city: Buzau state: Buzău country: Romania name: Florin Lucian Matei role: PRINCIPAL_INVESTIGATOR lat: 45.15 lon: 26.83333 facility: Spitalul Clinic Județean de Urgență status: NOT_YET_RECRUITING city: Craiova state: Dolj zip: 200642 country: Romania name: Octavian Istratoaie role: PRINCIPAL_INVESTIGATOR lat: 44.31667 lon: 23.8 facility: Private Practice - Dr. Mercea Corina Delia status: NOT_YET_RECRUITING city: Baia Mare state: Maramureș zip: 430123 country: Romania name: DELIA MERCEA role: PRINCIPAL_INVESTIGATOR lat: 47.65529 lon: 23.57381 facility: CMI DNBM Dr. Pop Lavinia status: RECRUITING city: Baia Mare state: Maramureș zip: 430222 country: Romania name: Lavinia Pop role: PRINCIPAL_INVESTIGATOR lat: 47.65529 lon: 23.57381 facility: SC Dentosim Queen SRL - Centrul Medical Diamed status: RECRUITING city: Târgu Mureș state: Mureș zip: 540098 country: Romania name: Daniela Ciomos role: PRINCIPAL_INVESTIGATOR lat: 46.54245 lon: 24.55747 facility: Cardiomed status: NOT_YET_RECRUITING city: Târgu Mureș state: Mureș zip: 540124 country: Romania name: Imre Benedek role: PRINCIPAL_INVESTIGATOR lat: 46.54245 lon: 24.55747 facility: Centrul Medical Mediab status: NOT_YET_RECRUITING city: Târgu-Mureș state: Mureș zip: 540142 country: Romania name: Carmen Crisan role: PRINCIPAL_INVESTIGATOR lat: 46.54245 lon: 24.55747 facility: Centrul Medical Mediab status: NOT_YET_RECRUITING city: Târgu-Mureș state: Mureș zip: 540142 country: Romania name: Adriana Cif role: PRINCIPAL_INVESTIGATOR lat: 46.54245 lon: 24.55747 facility: Private Practice - Dr. Cristian Podoleanu status: NOT_YET_RECRUITING city: Târgu-Mureș state: Mureș zip: 540143 country: Romania name: Cristian Podoleanu role: PRINCIPAL_INVESTIGATOR lat: 46.54245 lon: 24.55747 facility: Cabinet Medical Dr.Geru status: RECRUITING city: Timisoara state: Timiș zip: 300288 country: Romania name: Polina Geru role: PRINCIPAL_INVESTIGATOR lat: 45.75372 lon: 21.22571 facility: Institutul de Boli Cardiovasculare Timișoara status: NOT_YET_RECRUITING city: Timișoara state: Timiș zip: 300310 country: Romania name: Dan Gaita role: PRINCIPAL_INVESTIGATOR lat: 45.75372 lon: 21.22571 facility: C.M.D.T.A. Neomed status: NOT_YET_RECRUITING city: Brasov zip: 500283 country: Romania name: Sanziana Barbulescu role: PRINCIPAL_INVESTIGATOR lat: 45.64861 lon: 25.60613 facility: Spitalul Universitar de Urgență București status: NOT_YET_RECRUITING city: București zip: 050098 country: Romania name: DRAGOS VINEREANU role: PRINCIPAL_INVESTIGATOR lat: 44.42802 lon: 26.09665 facility: Milena Sante status: RECRUITING city: Galați zip: 800001 country: Romania name: Cristina-Victoria Mistodie role: PRINCIPAL_INVESTIGATOR lat: 45.45 lon: 28.05 facility: Diamed Obesity status: RECRUITING city: Galați zip: 800291 country: Romania name: Magdalena Morosanu role: PRINCIPAL_INVESTIGATOR lat: 45.45 lon: 28.05 facility: Centrul Medical Consultmed status: NOT_YET_RECRUITING city: Iași zip: 700547 country: Romania name: Delia Reurean-Pintilei role: PRINCIPAL_INVESTIGATOR lat: 47.16667 lon: 27.6 facility: Cardiomed Iași status: NOT_YET_RECRUITING city: Iași zip: 700687 country: Romania name: Sirona Lupu role: PRINCIPAL_INVESTIGATOR lat: 47.16667 lon: 27.6 facility: Clinica Korall status: RECRUITING city: Satu Mare zip: 440055 country: Romania name: Adriana Filimon role: PRINCIPAL_INVESTIGATOR lat: 47.79926 lon: 22.86255 facility: Policlinica Astra Sibiu status: RECRUITING city: Sibiu zip: 550371 country: Romania name: Georgiana Nicolescu role: PRINCIPAL_INVESTIGATOR lat: 45.8 lon: 24.15 facility: IN-DIA status: NOT_YET_RECRUITING city: Lucenec state: Banskobystrický Kraj zip: 984 01 country: Slovakia name: Livia Tomasova role: PRINCIPAL_INVESTIGATOR lat: 48.33249 lon: 19.66708 facility: ENRIN, s.r.o. status: NOT_YET_RECRUITING city: Rimavská Sobota state: Banskobystrický Kraj zip: 979 01 country: Slovakia name: Jana Horvath Bercikova role: PRINCIPAL_INVESTIGATOR lat: 48.38284 lon: 20.02239 facility: Cliniq s.r.o. status: NOT_YET_RECRUITING city: Bratislava state: Bratislavský Kraj zip: 81109 country: Slovakia name: Alena Ftacnikova role: PRINCIPAL_INVESTIGATOR lat: 48.14816 lon: 17.10674 facility: Sin Azucar status: NOT_YET_RECRUITING city: Malacky state: Bratislavský Kraj zip: 901 01 country: Slovakia name: Barbora Zobokova role: PRINCIPAL_INVESTIGATOR lat: 48.43604 lon: 17.02188 facility: Human Care s.r.o. status: NOT_YET_RECRUITING city: Kosice state: Košický Kraj zip: 04001 country: Slovakia name: Viera Donicova role: PRINCIPAL_INVESTIGATOR lat: 48.71395 lon: 21.25808 facility: Tatratrial s.r.o. status: NOT_YET_RECRUITING city: Rožňava state: Košický Kraj zip: 04801 country: Slovakia name: Beata Lachova role: PRINCIPAL_INVESTIGATOR lat: 48.66009 lon: 20.53758 facility: Areteus s.r.o. status: NOT_YET_RECRUITING city: Trebisov state: Košický Kraj zip: 075 01 country: Slovakia name: Dasa Skripova role: PRINCIPAL_INVESTIGATOR lat: 48.62858 lon: 21.71954 facility: Fakultná nemocnica Nitra status: NOT_YET_RECRUITING city: Nitra state: Nitriansky Kraj zip: 950 01 country: Slovakia name: Peter Minarik role: PRINCIPAL_INVESTIGATOR lat: 48.30763 lon: 18.08453 facility: IMCORE status: NOT_YET_RECRUITING city: Presov state: Prešovský Kraj zip: 080 01 country: Slovakia name: Luboslava Kocurova Frajtova role: PRINCIPAL_INVESTIGATOR lat: 48.99839 lon: 21.23393 facility: MEDISPOL status: NOT_YET_RECRUITING city: Presov state: Prešovský Kraj zip: 080 01 country: Slovakia name: Daniela Vinanska role: PRINCIPAL_INVESTIGATOR lat: 48.99839 lon: 21.23393 facility: MEDIKALS status: NOT_YET_RECRUITING city: Piešťany state: Trnavský Kraj zip: 921 01 country: Slovakia name: Slavka Kalinova role: PRINCIPAL_INVESTIGATOR lat: 48.59479 lon: 17.82591 facility: ENDIAMED s.r.o status: RECRUITING city: Dolny Kubin state: Žilinský Kraj zip: 026 01 country: Slovakia name: Jan Truban role: PRINCIPAL_INVESTIGATOR lat: 49.20983 lon: 19.30341 facility: JM-Interna s.r.o status: NOT_YET_RECRUITING city: Dolny Kubin state: Žilinský Kraj zip: 02601 country: Slovakia name: Jan Micik role: PRINCIPAL_INVESTIGATOR lat: 49.20983 lon: 19.30341 facility: NEDÚ - Národný endokrinologický a diabetologický ústav n.o. status: NOT_YET_RECRUITING city: Lubochna state: Žilinský Kraj zip: 034 91 country: Slovakia name: Emil Martinka role: PRINCIPAL_INVESTIGATOR lat: 49.12011 lon: 19.16891 facility: AMBORA s.r.o. Interna ambulancia status: NOT_YET_RECRUITING city: Martin state: Žilinský Kraj zip: 036 01 country: Slovakia name: Boris Raska role: PRINCIPAL_INVESTIGATOR lat: 49.06651 lon: 18.92399 facility: MediPrax, s.r.o. status: NOT_YET_RECRUITING city: Trstena state: Žilinský Kraj zip: 028 01 country: Slovakia name: Ivana Škerdová role: PRINCIPAL_INVESTIGATOR lat: 49.36101 lon: 19.61249 facility: CHUAC-Complejo Hospitalario Universitario A Coruña status: NOT_YET_RECRUITING city: A Coruña state: A Coruña [La Coruña] zip: 15001 country: Spain name: Jose Luis Diaz Diaz role: PRINCIPAL_INVESTIGATOR lat: 43.37135 lon: -8.396 facility: Complejo Hospitalario Universitario de Ferrol (CHUF)- Hospital Naval status: NOT_YET_RECRUITING city: Ferrol state: A Coruña [La Coruña] zip: 15405 country: Spain name: DIEGO BELLIDO GUERRERO role: PRINCIPAL_INVESTIGATOR lat: 43.4896 lon: -8.21942 facility: CHUS - Hospital Clinico Universitario status: NOT_YET_RECRUITING city: Santiago de Compostela state: A Coruña [La Coruña] zip: 15706 country: Spain name: Jose Ramon Gonzalez-Juanatey role: PRINCIPAL_INVESTIGATOR lat: 42.88052 lon: -8.54569 facility: Hospital de Denia Marina Salud status: NOT_YET_RECRUITING city: Dénia state: Alicante zip: 03700 country: Spain name: ALFONSO VALLE role: PRINCIPAL_INVESTIGATOR lat: 38.84078 lon: 0.10574 facility: Hospital Universitario Reina Sofia status: NOT_YET_RECRUITING city: Cordoba state: Andalucía zip: 14004 country: Spain name: Jose Lopez Miranda role: PRINCIPAL_INVESTIGATOR lat: 37.89155 lon: -4.77275 facility: Hospital Unviersitario Virgen Nieves status: NOT_YET_RECRUITING city: Granada state: Andalucía zip: 18014 country: Spain name: Pablo González Bustos role: PRINCIPAL_INVESTIGATOR lat: 37.18817 lon: -3.60667 facility: Hospital Universitario Virgen de la Victoria status: NOT_YET_RECRUITING city: Malaga state: Andalucía zip: 29010 country: Spain name: Francisco Tinahones Madueno role: PRINCIPAL_INVESTIGATOR lat: 36.72016 lon: -4.42034 facility: Hospital de Cabueñes status: NOT_YET_RECRUITING city: Gijón state: Asturias zip: 33394 country: Spain name: Juan Rondán role: PRINCIPAL_INVESTIGATOR lat: 43.53573 lon: -5.66152 facility: Hospital Universitari Son Espases status: NOT_YET_RECRUITING city: Palma state: Balears [Baleares] zip: 07120 country: Spain name: Santiago Tofe Povedano role: PRINCIPAL_INVESTIGATOR lat: 39.56939 lon: 2.65024 facility: Hospital Germans Trias i Pujol status: NOT_YET_RECRUITING city: Badalona state: Barcelona [Barcelona] zip: 08916 country: Spain name: Núria Alonso Pedrol role: PRINCIPAL_INVESTIGATOR lat: 41.45004 lon: 2.24741 facility: Parc de Salut Mar - Hospital del Mar status: NOT_YET_RECRUITING city: Barcelona state: Barcelona [Barcelona] zip: 08003 country: Spain name: Miguel Achirica role: PRINCIPAL_INVESTIGATOR lat: 41.38879 lon: 2.15899 facility: Hospital Universitario Marqués de Valdecilla status: NOT_YET_RECRUITING city: Santander state: Cantabria zip: 39008 country: Spain name: Marta Martin Millan role: PRINCIPAL_INVESTIGATOR lat: 43.46472 lon: -3.80444 facility: Hospital Clínic de Barcelona status: NOT_YET_RECRUITING city: Barcelona state: Catalunya [Cataluña] zip: 08036 country: Spain name: RAMON ESTRUCH role: PRINCIPAL_INVESTIGATOR lat: 41.38879 lon: 2.15899 facility: Hospital de la Santa Creu i Sant Pau status: NOT_YET_RECRUITING city: Barcelona state: Catalunya [Cataluña] zip: 08041 country: Spain name: Xavier Garcia-Moll role: PRINCIPAL_INVESTIGATOR lat: 41.38879 lon: 2.15899 facility: Hospital Universitari de Bellvitge status: NOT_YET_RECRUITING city: L'Hospitalet de Llobregat state: Catalunya [Cataluña] zip: 08907 country: Spain name: Xavier Pintó role: PRINCIPAL_INVESTIGATOR lat: 41.35967 lon: 2.10028 facility: Consorci Sanitari Integral. Hospital Moisés Broggi, Sant Joan Despí status: NOT_YET_RECRUITING city: Sant Joan Despí state: Catalunya [Cataluña] zip: 08970 country: Spain name: CARLOS JERICO ALBA role: PRINCIPAL_INVESTIGATOR lat: 41.36718 lon: 2.0574 facility: Hospital Virgen del Camino status: NOT_YET_RECRUITING city: Sanlúcar de Barrameda state: Cádiz zip: 11540 country: Spain name: Manuel Beltran Robles role: PRINCIPAL_INVESTIGATOR lat: 36.77808 lon: -6.3515 facility: Hospital Virgen de las Montañas status: NOT_YET_RECRUITING city: Villamartin state: Cádiz zip: 11650 country: Spain name: Enrique Garcia del Rio role: PRINCIPAL_INVESTIGATOR lat: 36.85979 lon: -5.64485 facility: Hospital Universitari de Girona Doctor Josep Trueta status: NOT_YET_RECRUITING city: Girona state: Girona [Gerona] zip: 17007 country: Spain name: Eduardo Esteve role: PRINCIPAL_INVESTIGATOR lat: 41.98311 lon: 2.82493 facility: Hospital Insular de Gran Canaria status: NOT_YET_RECRUITING city: Las Palmas de Gran Canaria state: Las Palmas zip: 35016 country: Spain name: Rosa María Sánchez Hernández role: PRINCIPAL_INVESTIGATOR lat: 28.09973 lon: -15.41343 facility: Hospital Universitario Fundacion ALcorcon status: NOT_YET_RECRUITING city: Alcorcón state: Madrid, Comunidad De zip: 28922 country: Spain name: Carlos Guijarro Herraiz role: PRINCIPAL_INVESTIGATOR lat: 40.34582 lon: -3.82487 facility: Hospital Universitario Ramón y Cajal status: NOT_YET_RECRUITING city: Madrid state: Madrid, Comunidad De zip: 28034 country: Spain name: Luis Manzano Espinosa role: PRINCIPAL_INVESTIGATOR lat: 40.4165 lon: -3.70256 facility: Hospital Universitario Puerta de Hierro Majadahonda status: NOT_YET_RECRUITING city: Majadahonda state: Madrid, Comunidad De zip: 28220 country: Spain name: Juan Manuel Escudier Villa role: PRINCIPAL_INVESTIGATOR lat: 40.47353 lon: -3.87182 facility: Hospital Universitario Quironsalud Madrid status: NOT_YET_RECRUITING city: Pozuelo de Alarcón state: Madrid zip: 28223 country: Spain name: Esteban Jodar Gimeno role: PRINCIPAL_INVESTIGATOR lat: 40.43293 lon: -3.81338 facility: Hospital Clínico Universitario Virgen de la Arrixaca status: NOT_YET_RECRUITING city: El Palmar, Murcia state: Murcia, Región De zip: 30120 country: Spain name: Domingo Pascual Figal role: PRINCIPAL_INVESTIGATOR facility: Vithas Hospital Sevilla status: RECRUITING city: Seville state: Sevilla zip: 41950 country: Spain name: Cristobal Morales Portillo role: PRINCIPAL_INVESTIGATOR lat: 37.38283 lon: -5.97317 facility: Hospital Universitari Sant Joan de Reus status: NOT_YET_RECRUITING city: Reus state: Tarragona [Tarragona] zip: 43204 country: Spain name: Daiana Ibarretxe Gerediaga role: PRINCIPAL_INVESTIGATOR lat: 41.15612 lon: 1.10687 facility: Hospital Clinico de Valencia status: NOT_YET_RECRUITING city: Valencia state: Valenciana, Comunitat zip: 46010 country: Spain name: Julio Nunez Villota role: PRINCIPAL_INVESTIGATOR lat: 39.46975 lon: -0.37739 facility: Hospital Arnau de Vilanova status: NOT_YET_RECRUITING city: Valencia state: Valenciana, Comunitat zip: 46015 country: Spain name: JUAN COSIN SALES role: PRINCIPAL_INVESTIGATOR lat: 39.46975 lon: -0.37739 facility: Hospital General Universitario de Valencia status: NOT_YET_RECRUITING city: Valencia state: València zip: 46014 country: Spain name: Francesc Puchades role: PRINCIPAL_INVESTIGATOR lat: 39.46975 lon: -0.37739 facility: Hospital Infanta Elena status: NOT_YET_RECRUITING city: Huelva zip: 21007 country: Spain name: Manuel Jesús Romero-Jiménez role: PRINCIPAL_INVESTIGATOR lat: 37.26638 lon: -6.94004 facility: Complejo Hospitalario de Jaén status: NOT_YET_RECRUITING city: Jaén zip: 23007 country: Spain name: Francisco Gomez Delgado role: PRINCIPAL_INVESTIGATOR lat: 37.76922 lon: -3.79028 facility: Hospital Lucus Augusti status: NOT_YET_RECRUITING city: Lugo zip: 27003 country: Spain name: Rosa Argüeso Armesto role: PRINCIPAL_INVESTIGATOR lat: 43.00992 lon: -7.55602 facility: Hospital Universitario La Paz status: NOT_YET_RECRUITING city: Madrid zip: 28029 country: Spain name: Jose Mostaza role: PRINCIPAL_INVESTIGATOR lat: 40.4165 lon: -3.70256 facility: Hospital Clinico San Carlos status: NOT_YET_RECRUITING city: Madrid zip: 28040 country: Spain name: Manuel Mendez role: PRINCIPAL_INVESTIGATOR lat: 40.4165 lon: -3.70256 facility: Hospital Universitario 12 de Octubre status: NOT_YET_RECRUITING city: Madrid zip: 28041 country: Spain name: Agustin Blanco Echevarria role: PRINCIPAL_INVESTIGATOR lat: 40.4165 lon: -3.70256 facility: Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca status: NOT_YET_RECRUITING city: Salamanca zip: 37007 country: Spain name: ARMANDO OTERINO MANZANAS role: PRINCIPAL_INVESTIGATOR lat: 40.96882 lon: -5.66388 facility: Hospital General de Segovia status: NOT_YET_RECRUITING city: Segovia zip: 40002 country: Spain name: FERNANDO Gomez PERALTA role: PRINCIPAL_INVESTIGATOR lat: 40.94808 lon: -4.11839 facility: Hospital Universitario Virgen Macarena status: NOT_YET_RECRUITING city: Sevilla zip: 41009 country: Spain name: Rafael Jesús Hidalgo Urbano role: PRINCIPAL_INVESTIGATOR lat: 37.38283 lon: -5.97317 facility: Hospital Universitario Virgen Del Rocio status: NOT_YET_RECRUITING city: Sevilla zip: 41013 country: Spain name: Luis Beltrán role: PRINCIPAL_INVESTIGATOR lat: 37.38283 lon: -5.97317 facility: Hospital Universitario Miguel Servet status: NOT_YET_RECRUITING city: Zaragoza zip: 50009 country: Spain name: Fernando Civeira role: PRINCIPAL_INVESTIGATOR lat: 41.65606 lon: -0.87734 facility: Changhua Christian Hospital status: NOT_YET_RECRUITING city: Changhua County state: Changhua zip: 50006 country: Taiwan name: Ching-Pei Chen role: PRINCIPAL_INVESTIGATOR facility: Chang Gung Memorial Hospital at Kaohsiung status: NOT_YET_RECRUITING city: Kaohsiung Niao Sung Dist state: Kaohsiung zip: 83301 country: Taiwan name: Chih-Yuan Fang role: PRINCIPAL_INVESTIGATOR facility: Chung Shan Medical University Hospital status: NOT_YET_RECRUITING city: Taichung City state: Taichung zip: 402 country: Taiwan name: Kwo-Chang Ueng role: PRINCIPAL_INVESTIGATOR lat: 24.1469 lon: 120.6839 facility: Chi Mei Medical Center status: NOT_YET_RECRUITING city: Tainan City state: Tainan zip: 71004 country: Taiwan name: Chon Seng Hong role: PRINCIPAL_INVESTIGATOR lat: 22.99083 lon: 120.21333 facility: Cathay General Hospital status: NOT_YET_RECRUITING city: Taipei City state: Taipei zip: 106 country: Taiwan name: Chi-Hung Huang role: PRINCIPAL_INVESTIGATOR lat: 25.04776 lon: 121.53185 facility: Shin Kong Wu Ho-Su Memorial Hospital status: NOT_YET_RECRUITING city: Taipei City state: Taipei zip: 111 country: Taiwan name: Kou-Gi Shyu role: PRINCIPAL_INVESTIGATOR lat: 25.04776 lon: 121.53185 facility: Tri-Service General Hospital status: NOT_YET_RECRUITING city: Taipei City state: Taipei zip: 114 country: Taiwan name: WEI-HSIANG LIN role: PRINCIPAL_INVESTIGATOR lat: 25.04776 lon: 121.53185 facility: National Yang Ming Chiao Tung University Hospital status: NOT_YET_RECRUITING city: Yilan City state: Yilan zip: 260006 country: Taiwan name: Hsuan-Ming Tsao role: PRINCIPAL_INVESTIGATOR lat: 24.757 lon: 121.753 facility: Kaohsiung Medical University Chung-Ho Memorial Hospital status: RECRUITING city: Kaohsiung zip: 807 country: Taiwan name: Tsung-Hsien Lin role: PRINCIPAL_INVESTIGATOR lat: 22.61626 lon: 120.31333 facility: Fu Jen Catholic University Hospital status: NOT_YET_RECRUITING city: New Taipei zip: 24352 country: Taiwan name: Shih-Chi Liu role: PRINCIPAL_INVESTIGATOR lat: 25.01111 lon: 121.44583 facility: National Cheng Kung University Hospital status: NOT_YET_RECRUITING city: Tainan zip: 704 country: Taiwan name: Yi-Ching Yang role: PRINCIPAL_INVESTIGATOR lat: 22.99083 lon: 120.21333 facility: National Taiwan University Hospital status: NOT_YET_RECRUITING city: Taipei zip: 10002 country: Taiwan name: Tzung-Dau Wang role: PRINCIPAL_INVESTIGATOR lat: 25.04776 lon: 121.53185 facility: Taipei Medical University Hospital status: NOT_YET_RECRUITING city: Taipei zip: 110 country: Taiwan name: Chun-Yao Huang role: PRINCIPAL_INVESTIGATOR lat: 25.04776 lon: 121.53185 facility: Taipei Veterans General Hospital status: NOT_YET_RECRUITING city: Taipei zip: 11217 country: Taiwan name: Chern-En Chiang role: PRINCIPAL_INVESTIGATOR lat: 25.04776 lon: 121.53185 facility: Chang Gung Medical Foundation-Linkou Branch status: NOT_YET_RECRUITING city: Taoyuan zip: 333 country: Taiwan name: Pao-Hsien Pao-Hsien Chu role: PRINCIPAL_INVESTIGATOR lat: 24.95233 lon: 121.20193 facility: Bristol Royal Infirmary status: NOT_YET_RECRUITING city: Bristol state: Bristol, City Of zip: BS2 8HW country: United Kingdom name: Paul Downie role: PRINCIPAL_INVESTIGATOR lat: 51.45523 lon: -2.59665 facility: Torbay Hospital status: NOT_YET_RECRUITING city: Torquay state: Devon zip: TQ2 7AA country: United Kingdom name: Jamie Smith role: PRINCIPAL_INVESTIGATOR lat: 50.46198 lon: -3.5252 facility: Royal Free London NHS Foundation Trust status: NOT_YET_RECRUITING city: London state: England zip: NW32QG country: United Kingdom name: Devaki Nair role: PRINCIPAL_INVESTIGATOR lat: 51.50853 lon: -0.12574 facility: Lister Hospital status: RECRUITING city: Stevenage state: Hertfordshire zip: SG1 4AB country: United Kingdom name: Mary Lynch role: PRINCIPAL_INVESTIGATOR lat: 51.90224 lon: -0.20256 facility: Hull and East Yorkshire Hospitals NHS Trust status: RECRUITING city: Hull state: Kingston Upon Hull zip: HU3 2JZ country: United Kingdom name: Deepa Narayanan role: PRINCIPAL_INVESTIGATOR lat: 53.7446 lon: -0.33525 facility: Panthera Biopartners - Manchester status: RECRUITING city: Rochdale state: Manchester zip: OL11 4AU country: United Kingdom name: Krishnakumar Radhakrishnan role: PRINCIPAL_INVESTIGATOR lat: 53.61766 lon: -2.1552 facility: Salford Royal Hospital status: RECRUITING city: Salford state: Manchester zip: M6 8HD country: United Kingdom name: John Gibson role: PRINCIPAL_INVESTIGATOR lat: 53.48771 lon: -2.29042 facility: Panthera Biopartners - Glasgow status: RECRUITING city: Glasgow state: Scotland zip: G51 4TY country: United Kingdom name: Raghavendra Madimchetty role: PRINCIPAL_INVESTIGATOR lat: 55.86515 lon: -4.25763 facility: Sunderland Royal Hospital status: RECRUITING city: Tyne And Wear zip: SR4 7TP country: United Kingdom name: Peter Carey role: PRINCIPAL_INVESTIGATOR facility: Sandwell General Hospital status: RECRUITING city: West Bromwich zip: B71 4HJ country: United Kingdom name: Inessa Tracey role: PRINCIPAL_INVESTIGATOR lat: 52.51868 lon: -1.9945 hasResults: False
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<|newrecord|> nctId: NCT06292000 id: 23-1721 briefTitle: Examining the Effects of Morning and Evening Exercise on Glucose Regulation in Adults With Prediabetes acronym: TExIS overallStatus: RECRUITING date: 2024-02-01 date: 2026-06 date: 2026-06 date: 2024-03-04 date: 2024-03-29 name: University of Colorado, Denver class: OTHER briefSummary: Purpose of the Study: This study is to learn more about how exercising at different times of the day (morning versus evening) affects metabolism of glucose in the body, sleep, activity outside of exercise, and other factors.
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