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<|newrecord|> nctId: NCT06262919 id: CDRB436I1401 briefTitle: Special Drug Use-results Surveillance of Tafinlar/Mekinist overallStatus: RECRUITING date: 2024-02-09 date: 2031-12-31 date: 2031-12-31 date: 2024-02-16 date: 2024-03-22 name: Novartis Pharmaceuticals class: INDUSTRY briefSummary: This is a prospective, mult... |
<|newrecord|> nctId: NCT06262906 id: BA-VCAP-01 briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA] overallStatus: WITHHELD date: 2024-02-16 date: 2024-04-25 name: [Redacted] hasResults: False |
<|newrecord|> nctId: NCT06262893 id: Shoulder nerve blocks briefTitle: Effect of Dexamethasone Adjuvant in Combined Supraclavicular Block and Suprascapular Block Versus Interscalene Block in Patients Undergoing Shoulder Arthroscopy overallStatus: NOT_YET_RECRUITING date: 2024-02-25 date: 2025-12 date: 2026-01 date: 202... |
<|newrecord|> nctId: NCT06262880 id: BIO-2305 briefTitle: Dietary Supplementation on Gastrointestinal Barrier Function overallStatus: RECRUITING date: 2024-02-06 date: 2024-12-20 date: 2025-02-06 date: 2024-02-16 date: 2024-03-08 name: Brightseed class: INDUSTRY briefSummary: The purpose of the current study is to exam... |
<|newrecord|> nctId: NCT06262867 id: ReadySetFood briefTitle: Early Allergen System Experience acronym: EASE overallStatus: NOT_YET_RECRUITING date: 2024-03-07 date: 2026-09-01 date: 2026-09-01 date: 2024-02-16 date: 2024-02-20 name: Prollergy dba Ready Set Food class: OTHER name: ObvioHealth briefSummary: Multiple cli... |
This study investigates the effectiveness of introducing common allergens to infants with the goal of preventing food allergies. The study will enroll 1,100 infants stratified by their risk of developing a food allergy who are assigned to either receive Ready. Set. Food! supplements or follow standard allergen introduc... |
The goal of this study is to assess how Ready. Set. Food! allergen introduction supplements improve the experience of parents introducing allergens, decrease healthcare costs related to food allergies, and decrease food allergy prevalence. conditions: Food Allergy in Infants studyType: INTERVENTIONAL phases: NA allocat... |
<|newrecord|> nctId: NCT06262854 id: AOU Careggi Firenze briefTitle: Efficacy and Safety of Stimulan® for the Treatment of Diabetic Foot Osteomyelitis. The BIG D-FOOT Study acronym: BIG D-FOOT overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-05-31 date: 2024-02-16 date: 2024-02-16 name: Az... |
<|newrecord|> nctId: NCT06262841 id: Murat Kaan Erdem briefTitle: Post-Surgical Morbidity and Bone Healing of Impacted Lower Third Molars: Piezosurgery vs. Conventional Instruments overallStatus: COMPLETED date: 2022-11-01 date: 2023-04-01 date: 2023-04-01 date: 2024-02-16 date: 2024-02-16 name: Ankara University class... |
<|newrecord|> nctId: NCT06262828 id: UW 24-064 briefTitle: HEARTWISE - P-CARDIAC for Chinese: Population-based Study acronym: HEARTWISE overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2027-01-31 date: 2027-04-30 date: 2024-02-16 date: 2024-02-16 name: The University of Hong Kong class: OTHER briefSummary: Card... |
<|newrecord|> nctId: NCT06262815 id: 2023-06806-01 briefTitle: The Utility of Treatment With Nasogastric Tube Placement for Small Bowel Obstruction acronym: NGTUBE-OBS overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-16 date: 2024-02-16 name: Daniel Wilhelms class: OTHER name: ... |
Definitive treatment for SBO is surgical adhesiolysis but there is debate regarding the timing of surgery, particularly in older adults. A large proportion of patients may be managed conservatively with oral contrast and repeated radiological evaluation and the obstruction will resolve in many patients within 24 to 48 ... |
To investigate the potential benefit of nasogastric tube placement in patients with SBO and the ability of frailty to prognosticate outcomes in older adults better evidence is needed. conditions: Small Bowel Obstruction conditions: Frailty conditions: Nasogastric Tube studyType: OBSERVATIONAL observationalModel: CASE_C... |
<|newrecord|> nctId: NCT06262802 id: 123123 briefTitle: Volumetric Changes in Large Cystic Lesions Using Active Decompression and Distraction Sugosteogenesis vs Passive Decompression overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-09-01 date: 2025-03-01 date: 2024-02-16 date: 2024-02-16 name: Radwa Hydar ... |
<|newrecord|> nctId: NCT06262789 id: 49RC23_0011 briefTitle: RAT-HEMATO : Return to Work After Malignant Hemopathy acronym: RAT-HEMATO overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2027-04-01 date: 2027-04-01 date: 2024-02-16 date: 2024-02-16 name: University Hospital, Angers class: OTHER_GOV briefSummary: R... |
<|newrecord|> nctId: NCT06262776 id: SIRZOSTER1.01 briefTitle: Safety and Immunogenicity of Recombinant Zoster Vaccine for Kidney Transplant Recipients acronym: SIR ZOSTER overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-06 date: 2026-11 date: 2024-02-16 date: 2024-02-16 name: Central Adelaide Local Health Ne... |
1. Are there differences in vaccination immunological responses in kidney transplant patients on different immunosuppression regimens? |
2. Are there differences in vaccination immunological responses between kidney transplant patients and their healthy co-habitants? Participants will all receive a 2-dose course of SHINGRIX recombinant Zoster vaccination, and have immunological responses measured and compared at 5 timepoints between 1 week to 1 year pos... |
<|newrecord|> nctId: NCT06262763 id: HILT for SIJP briefTitle: High-intensity Laser Therapy for Sacroiliac Joint Pain acronym: Girls overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-03 date: 2023-04-28 date: 2024-03-28 date: 2024-02-16 date: 2024-02-16 name: Kafrelsheikh University class: OTHER briefSummary: Effect o... |
<|newrecord|> nctId: NCT06262750 id: 00375/23 briefTitle: Evaluation of Safety and Efficacy of Anticoagulation Treatment in Patients With Splanchnic Vein Thrombosis: SAPIENT Study acronym: SAPIENT overallStatus: RECRUITING date: 2023-12-01 date: 2023-12-01 date: 2025-11-01 date: 2024-02-16 date: 2024-02-16 name: Fondaz... |
<|newrecord|> nctId: NCT06262737 id: RBHP 2023 CHIAMBARETTA id: 2023-A01121-44 type: REGISTRY domain: ANSM briefTitle: Single-center Study Measuring OSDI Dry Eye Score in Patients Undergoing an Anti-VEGF Induction Protocol acronym: PISO overallStatus: RECRUITING date: 2023-09-30 date: 2024-10-01 date: 2025-10-01 date: ... |
<|newrecord|> nctId: NCT06262724 id: Perforator Flaps briefTitle: Breast Reshaping Following Massive Weight Loss overallStatus: COMPLETED date: 2021-08-01 date: 2023-08-01 date: 2024-01-01 date: 2024-02-16 date: 2024-02-26 name: Ain Shams University class: OTHER briefSummary: Reliability of Chest Wall Perforator Flaps ... |
<|newrecord|> nctId: NCT06262711 id: 321917 briefTitle: Effects of Vitamin C on Skeletal Muscle acronym: VICS overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-03 date: 2025-03 date: 2024-02-16 date: 2024-02-16 name: University of East Anglia class: OTHER name: The Norfolk and Norwich University Hospitals NHS ... |
<|newrecord|> nctId: NCT06262698 id: 81825902.903/148 briefTitle: The Effect of HBM-Based Education on Nursing Students acronym: HBM overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2024-12-31 date: 2025-06-30 date: 2024-02-16 date: 2024-02-16 name: Kafkas University class: OTHER briefSummary: The purpose of th... |
Research hypotheses: |
Hypothesis 01: There is no effect of HBM-based education on CAM knowledge level among nursing students. |
Hypothesis 1: There is an effect of HBM-based education on CAM knowledge level among nursing students. |
Hypothesis 02: There is no effect of HBM-based education on CAM attitude level among nursing students. |
Hypothesis 2: There is an effect of HBM-based education on CAM attitude level among nursing students. |
Hypothesis 03: There is no effect of HBM-based education on health beliefs related to medication use among nursing students. |
Hypothesis 3: There is an effect of HBM-based education on health beliefs related to medication use among nursing students. conditions: Nursing conditions: Evidence-Based Nursing studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The experimental group ... |
<|newrecord|> nctId: NCT06262685 id: 2023-509418-12-00 briefTitle: Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins acronym: PREVESTATGx overallStatus: NOT_YET_RECRUITING date: 2024-03-04 date: 2025-02-10 date: 2025-03-04 date: 2024-02-16 date: 2024-02-16 name: Insti... |
<|newrecord|> nctId: NCT06262672 id: PR0319R01 briefTitle: Evaluation of Some Parameters in University Students During the COVİD-19 Epidemic Process overallStatus: COMPLETED date: 2021-05-20 date: 2021-11-20 date: 2021-11-20 date: 2024-02-16 date: 2024-02-28 name: Kırklareli University class: OTHER briefSummary: The ph... |
<|newrecord|> nctId: NCT06262659 id: 2023-142 briefTitle: The Effect of Ultrasonography on Blood Flow,Vessel Diameter,and Depth Measurements in Dialysis Patients With Fistula overallStatus: RECRUITING date: 2024-03-08 date: 2024-06-10 date: 2024-09-10 date: 2024-02-16 date: 2024-03-12 name: Kudret Atakan Tekin class: O... |
<|newrecord|> nctId: NCT06262646 id: NTEC-2023-677 briefTitle: Video-conferencing FACT for Young Children With Special Needs overallStatus: RECRUITING date: 2024-02-01 date: 2025-01-31 date: 2026-01-31 date: 2024-02-16 date: 2024-02-16 name: Chinese University of Hong Kong class: OTHER name: Hong Kong Christian Service... |
Background: Parental caregiving for children with special needs is associated with significant stress, potentially impairing parental and familial functioning. Acceptance and Commitment Therapy (ACT) has shown promise in bolstering mental health across diverse populations. Preliminary findings from a feasibility trial ... |
Methods: Expanding upon prior research, this definitive RCT compares FACT to standard parenting advice, correcting for earlier limitations through increased sample size and rigorous methodology. Assessments will be conducted at baseline, post-intervention (4-8 weeks), and 6-month follow-up. |
Results: The study anticipates that FACT will demonstrate superior outcomes in promoting well-being among parents compared to parenting advice alone. |
Conclusion: By leveraging videoconferencing for therapy delivery, the RCT aims to improve access to mental health interventions and emphasize the importance of psychological health among parents of special needs children. This could foster greater recognition and proactive management of mental health within this popula... |
<|newrecord|> nctId: NCT06262633 id: CRE-2023.079 briefTitle: A Multi-centre Trial on Targeted Microwave Ablation (TMA) for Localized Prostate Cancer overallStatus: RECRUITING date: 2024-03-15 date: 2026-04-30 date: 2026-06-30 date: 2024-02-16 date: 2024-03-19 name: Chinese University of Hong Kong class: OTHER briefSum... |
<|newrecord|> nctId: NCT06262620 id: 2022-NHLHCRF-LX-01-0201-06 briefTitle: The Comparisonof Mediastinal/Hilar Lymph Node Biopsies by EBUS-TBNA, EBUS-TBCB, and EBUS-TBFB overallStatus: NOT_YET_RECRUITING date: 2024-02-18 date: 2026-02-18 date: 2026-02-18 date: 2024-02-16 date: 2024-02-16 name: China-Japan Friendship Ho... |
Participants will divided into EBUS-TBNA group, EBUS-TBCB group, and EBUS-TBFB group at a 1:1:1 ratio by using central, computerized random sequence, and then undertake EBUS-TBNA, EBUS-TBCB, or EBUS-TBFB according to the group. |
Researchers will compare the adequacy of sampling by the three biopsy techniques, their sample quality, diagnostic rate, and incidence of each adverse events. conditions: Lymphadenopathy Hilar conditions: Lymphadenopathy Mediastinal studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL... |
<|newrecord|> nctId: NCT06262607 id: CLE400-NP-201 briefTitle: A Study of CLE-400 (Topical Gel) for the Treatment of Chronic Pruritus in Adult Subjects With Notalgia Paresthetica overallStatus: RECRUITING date: 2024-01-29 date: 2024-12-31 date: 2025-01-15 date: 2024-02-16 date: 2024-04-17 name: Clexio Biosciences Ltd. ... |
<|newrecord|> nctId: NCT06262594 id: L'ÉTOILE briefTitle: Lemborexant Treatment of Insomnia Linked to Epilepsy acronym: L'ÉTOILE overallStatus: NOT_YET_RECRUITING date: 2024-02-08 date: 2025-02-08 date: 2026-02-08 date: 2024-02-16 date: 2024-02-16 name: University of Manitoba class: OTHER name: Duke University briefSum... |
<|newrecord|> nctId: NCT06262581 id: 2021-FXY-471 briefTitle: Neoadjuvant Tisleizumab(BGB-A317) for dMMR/MSI-H Non-late Stage CRC Patients Before Surgery overallStatus: RECRUITING date: 2023-09-23 date: 2024-11-30 date: 2025-12-31 date: 2024-02-16 date: 2024-02-16 name: Sun Yat-sen University class: OTHER briefSummary:... |
<|newrecord|> nctId: NCT06262568 id: Soh-Med-23-03-18MS briefTitle: Effect of Guidelines on Nurses' Awareness Toward HRP and Maternal Near Miss Cases overallStatus: RECRUITING date: 2023-04-01 date: 2024-03-01 date: 2024-06-01 date: 2024-02-16 date: 2024-02-16 name: Sohag University class: OTHER briefSummary: The curre... |
<|newrecord|> nctId: NCT06262555 id: TYGH111061 briefTitle: Novel Light Delivery Method for Performing Transbronchial Photodynamic Therapy for Peripheral Lung Cancer overallStatus: RECRUITING date: 2024-03 date: 2024-06-30 date: 2024-12-31 date: 2024-02-16 date: 2024-02-16 name: Taoyuan General Hospital class: OTHER_GO... |
<|newrecord|> nctId: NCT06262542 id: 111016 briefTitle: Efficacy and Safety of Chinese Herb Medicine-Moxibustion Therapy on Chemotherapy-Induced Leukopenia overallStatus: RECRUITING date: 2024-03-13 date: 2024-12-31 date: 2024-12-31 date: 2024-02-16 date: 2024-04-12 name: Taichung Armed Forces General Hospital class: O... |
Current conventional treatments primarily involve colony-stimulating factors (G-CSF and GM-CSF) to accelerate neutrophil recovery and regulate granulocyte production. However, G-CSF is costly and adds financial burden, and its use is restricted to cases meeting specific criteria. Additionally, rapid changes in patients... |
Traditional Chinese Medicine (TCM) has been a long-standing medical practice in Eastern societies and is a legally recognized healthcare option in Taiwan, covered by national health insurance. TCM includes acupuncture, moxibustion, and Chinese herbal medicine, all of which have been researched for their potential in ad... |
<|newrecord|> nctId: NCT06262529 id: 22-AOI-06 briefTitle: Neurocognitive Impairment After Ischemic Stroke acronym: COG-TRA-Y MRI overallStatus: RECRUITING date: 2024-02-09 date: 2025-02-09 date: 2027-02-09 date: 2024-02-16 date: 2024-02-16 name: Centre Hospitalier Universitaire de Nice class: OTHER briefSummary: Affec... |
Studies assessing post-stroke cognition in young patients reported an alarming prevalence of cognitive impairment, affecting about 60% of stroke survivors between 4 and 12 months after the acute event. However, longitudinal data on neurocognitive trajectories (i.e., the evolution of cognitive impairment over time) in y... |
Repeated neurocognitive study of young patients with ischemic stroke will enable: a description of the prevalence of impaired global cognitive efficiency, an analysis of the specific neurocognitive domains affected, and the tracing of trajectories of recovery from cognitive impairment over time, in terms of global cogn... |
Up to date, the clinic-radiological predictors and associated factors of neurocognitive impairment after ischemic stroke in young patients have not been studied. Ischemic stroke causes acute brain lesions of the gray matter (GM) and white matter (WM). Numerous studies suggest that cognitive health may be more closely l... |
The aim of this study is to study whether the extension of pre-existing and acute white matter lesions is associated with poorer cognitive recovery after ischemic stroke, both in terms of global cognitive performance and impairment in specific neurocognitive domains. conditions: Acute Ischemic Stroke studyType: INTERVE... |
<|newrecord|> nctId: NCT06262516 id: CASE2824 briefTitle: Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2027-01-01 date: 2029-01-01 date: 2024-02-16 date: 2024-02-16 name: Case Comprehensive Cancer Center clas... |
* To determine oncologic outcomes, specifically 2-year recurrence-free survival |
* To determine other oncologic outcomes including treatment-free, cancer-specific and overall survival |
* To determine time to recurrence and recurrence patterns |
* To determine use of adjuvant therapies |
* To determine perioperative complications |
Participants will undergo nephroureterectomy with or without lymph node dissection. Researchers will compare these two groups to determine the oncologic efficacy of performing lymph node dissection. conditions: Urothelial Carcinoma studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL ... |
<|newrecord|> nctId: NCT06262503 id: P.T.REC/012/004810 briefTitle: the Influence of Virtual Reality Approach on Phantom Pain in Trans Tibial Amputation overallStatus: ACTIVE_NOT_RECRUITING date: 2023-10-01 date: 2024-02 date: 2024-03 date: 2024-02-16 date: 2024-02-20 name: Cairo University class: OTHER briefSummary: 1... |
2. To investigate the effect of Virtual reality (VR) on lower limb Function in trans tibial amputation. |
A sample size of 60 will be randomly allocated to two groups(30 in each group) , by using computer-generated random number list method. Control group will receive conventional physiotherapy(TENS- Phantom exercises and mirroring exercise) for reducing phantom pain in trans -tibial amputation and the experimental group w... |
<|newrecord|> nctId: NCT06262490 id: P.T.REC/012/004765 briefTitle: Impact of Pelvic Floor Rehabilitation Combined With Ultrasound Therapy on Osteomyoarticular Symptoms in Chronic Perineal Pain overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-08-01 date: 2024-09-01 date: 2024-02-16 date: 2024-02-16 name: C... |
<|newrecord|> nctId: NCT06262477 id: NL-TCZ-12280 briefTitle: A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male Participants overallStatus: RECRUITING date: 2024-01-02 date: 2024-11-30 date: 2024-11-30 date: 2024-02-16 date: 2024-02-1... |
<|newrecord|> nctId: NCT06262464 id: 17.361/ 07.12.2023 briefTitle: An OCD Prevention Programme for at Risk Adults acronym: ØCD overallStatus: RECRUITING date: 2024-02-09 date: 2024-03-29 date: 2024-04-01 date: 2024-02-16 date: 2024-03-18 name: Babes-Bolyai University class: OTHER name: Romanian National Authority for ... |
<|newrecord|> nctId: NCT06262451 id: 20-30182 id: 5R24AI118629 type: NIH link: https://reporter.nih.gov/quickSearch/5R24AI118629 briefTitle: Fecal Microbiota Transplant National Registry overallStatus: RECRUITING date: 2023-10-20 date: 2032-10 date: 2032-10 date: 2024-02-16 date: 2024-02-16 name: University of Californ... |
<|newrecord|> nctId: NCT06262438 id: MH22CAQ id: 2022-002886-14 type: EUDRACT_NUMBER id: 2023-505000-27 type: OTHER domain: EU CT Number briefTitle: CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients acronym: CHIP-AML22/Q overallStatus: RECRUITING date: 202... |
<|newrecord|> nctId: NCT06262425 id: ALC001NR004 briefTitle: rTMS Over S1 Enhance Motor Learning in Healthy People overallStatus: RECRUITING date: 2024-01-20 date: 2025-06-15 date: 2025-09-15 date: 2024-02-16 date: 2024-02-20 name: Neuron, Spain class: OTHER briefSummary: The purpose of this study is to compare the eff... |
<|newrecord|> nctId: NCT06262412 id: 2023-02193-01 briefTitle: Internet-delivered Cognitive-behaviour Therapy for Child and Adolescent Body Dysmorphic Disorder overallStatus: RECRUITING date: 2024-02-19 date: 2026-04-30 date: 2026-10-31 date: 2024-02-16 date: 2024-02-26 name: Karolinska Institutet class: OTHER name: Re... |
<|newrecord|> nctId: NCT06262399 id: ITL-2002-CL-999 id: 2022-003778-22 type: EUDRACT_NUMBER briefTitle: Long-Term Follow-Up (LTFU) of Subjects Treated With NTLA 2002 overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2040-04 date: 2040-04 date: 2024-02-16 date: 2024-02-16 name: Intellia Therapeutics class: INDUSTRY... |
<|newrecord|> nctId: NCT06262386 id: 202202172B0 briefTitle: Combined Relapse Prediction Model for Resectable Non-Small Cell Patients - a Prospective Clinical Feasibility Trial overallStatus: RECRUITING date: 2023-08-01 date: 2028-07-31 date: 2028-07-31 date: 2024-02-16 date: 2024-02-16 name: Chang Gung Memorial Hospit... |
In our preliminary analysis of previous study data, we observed that patients with a smaller reduction in circulating tumor cells (CTCs) within the first three days after surgery, followed by an increase on the third-day post-operation, are more likely to experience early relapse during regular monitoring. This pattern... |
The objective of our study is to employ screening based on circulating tumor cell dynamics and pathologic features to identify patients likely to experience early relapse and to assess the effectiveness of adjuvant therapy in these cases. conditions: Lung Cancer conditions: Relapse/Recurrence studyType: INTERVENTIONAL ... |
<|newrecord|> nctId: NCT06262373 id: 221321 briefTitle: Angular Pregnancy - Ultrasound Definition and Correlation With Clinical Outcomes overallStatus: COMPLETED date: 2017-10-01 date: 2019-10-01 date: 2019-10-01 date: 2024-02-16 date: 2024-02-16 name: King's College Hospital NHS Trust class: OTHER briefSummary: The ai... |
<|newrecord|> nctId: NCT06262360 id: P2023457 briefTitle: Changes in Pulmonary Ventilation Distribution Assessed by Electrical Impedance Tomography in Healthy Children Under General Anesthesia acronym: EIT_ped overallStatus: RECRUITING date: 2024-02-16 date: 2024-06-30 date: 2024-09-30 date: 2024-02-16 date: 2024-02-21... |
Children from 1 year-old to 6-year-old, ASA physical status I or II who will undergo elective circumcisions under general anesthesia associated with regional anesthesia (Penile Block10) at the One Day Clinic of H.U.D.E.R.F. (Hôpital des Enfants Reine Fabiola - Brussels - Belgium). |
Patients will be allocated to three different group in a ration of 1:1:1. |
* Group 1: spontaneous mask ventilation (20 patients). |
* Group 2: spontaneous laryngeal mask (LMA) ventilation (20 patients). |
* Group 3: spontaneous-pressure support LMA ventilation (LMA SV-PS) (20 patients). |
* Standard monitoring for the inductions of the anesthesia will include non-invasive blood pressure (NIBP), pulse oximetry (SpO2), Electrocardiogram (ECG), End-Tidal CO2 (EtCO2), End Tidal Sevoflurane concentration (EtSev %), inspired fraction of oxygen (FiO2), body temperature (rectal thermometer). |
Induction is based as well on the local routine protocols using an inhalation induction of the patient with Sevoflurane (Fet of 6-8%) and a recommended FiO2 from 80-90% maximum until the stabilization of the induction. Then the FiO2 will be decreased at least under 40% and Sevoflurane adapted to the need of the deepnes... |
Depending on the randomization, the patient will undergo the surgery either with spontaneous face mask ventilation (group 1), LMA spontaneous ventilation (group 2), or LMA SV-PS (group 3) (during which the pressure support will be adapted at the discretion of the anesthesiologist but with a tidal volume included in the... |
Electrical impedance tomography measurements: |
The effects of the spontaneous breathing (mask ventilation or LMA) or the pressure support ventilation (LMA SV-PS) on atelectasis formations and the distribution of the ventilation will be assessed using electrical impedance tomography. |
The device used during the study will be the "PulmoVista 500"; it will be provided by Dräger (Lübeck, Germany) free of charge and without any obligation or results/conclusions requested by Dräger. The device is approved CE (European regulation) and will be used in the conditions for which it has been designed. |
A reusable belt with 16 evenly spaced electrodes will be placed around the chest of each patient included in the study between the 4th and 6th ribs as recommended by Dräger. |
The EIT measurements will be taken of 4 different moments: |
T1: Before induction of the anesthesia in the preoperatory waiting room (and at least 30 min after the premedication). |
T2: After the induction of anesthesia (GA and penile block), just before the beginning of the surgical procedure. |
T3: After the end of the surgical procedure, just before discontinuing the general anesthesia. |
T4: Before the discharge of the PACU. conditions: Anesthesia, Pediatric studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Genera... |
<|newrecord|> nctId: NCT06262347 id: 2024-0115 id: UG1DA013732 type: NIH link: https://reporter.nih.gov/quickSearch/UG1DA013732 briefTitle: Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD acronym: TOME overallStatus: NOT_YET_... |
<|newrecord|> nctId: NCT06262334 id: Pro00133917 id: K23MD016123 type: NIH link: https://reporter.nih.gov/quickSearch/K23MD016123 briefTitle: Evaluating the Fade to Fitness Program: A Barbershop-based Program for Black Men overallStatus: RECRUITING date: 2024-03-20 date: 2024-06-15 date: 2024-06-15 date: 2024-02-16 dat... |
It is grounded in psychological and social theories like Self-Determination Theory, Motivational Interviewing, and Social Cognitive Theory. The program emphasizes the importance of making informed choices, feeling competent and connected, and learning through observation and modeling. Facilitators play a pivotal role, ... |
The program is structured into weekly sessions that tackle each health behavior, interspersed with off weeks; for community engagement, especially in barbershops, to discuss health topics and promote a healthier lifestyle. conditions: Health Related Quality of Life studyType: INTERVENTIONAL phases: NA allocation: NA in... |
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