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Patient Reported Experience Measures (PREMs) ask patients about their healthcare service experience. It gives them a voice to share their views. PREMs allow healthcare providers (HCPs) to see where care is good, and where they could improve. Vascular surgery is a surgical speciality looking after people's blood vessels... |
There is no PREM available for vascular patients. The research team want to create a PREM for this patient group. |
WHY IT IS IMPORTANT: |
A PREM allows HCPs to record and understand patients' experiences of their treatment. It gives patients a way to provide feedback on their healthcare experience. PREMs can help HCPs make changes to patients' care, identifying areas of good practice and areas for improvement. The Welsh Government is keen to support the ... |
AIMS: |
To develop a PREM specific to vascular surgery patients. |
RESEARCH PLAN: |
The research team will summarise the literature about PREMs in surgery. The research team will then run focus groups and interviews with patients and staff to create a 'draft' PREM for vascular patients in Wales. The 'draft' PREM will be translated into Welsh. |
In the second phase, a larger number of vascular patients (100-300 depending on how long the 'draft' PREM is) from hospitals across Wales will complete the questionnaire. Statistical tests will look at the results to see if the questionnaire works well to capture patients' experiences. Based on these results, small cha... |
PATIENT AND PUBLIC INVOLVEMENT: |
The patients' experience team at CAVUHB has reviewed our patients' materials. Our research team includes PPI co-applicants (DC and AH). DC a double amputee who has had many vascular operations. DC has experience raising awareness about vascular disease through public forums like the Limbless Association Charity and BBC... |
<|newrecord|> nctId: NCT06363162 id: LRR202404 briefTitle: Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery overallStatus: RECRUITING date: 2022-12-01 date: 2025-06-30 date: 2025-12-31 date: 2024-04-12 date: 2024-04-12 name: Beijing Tiantan Hospital class:... |
<|newrecord|> nctId: NCT06363149 id: 2024-11-DM-136 briefTitle: Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients overallStatus: RECRUITING date: 2024-04-12 date: 2025-09 date: 2025-09 date: 2024-04-12 date: 2024-04-16 name: Sanjay Gandhi Postgraduate Institute of Medical... |
Both DIC and septic shock individually are associated with very high mortality and morbidity and coexistence of both increase risk manifold. Organ dysfunction is a complication of both septic shock and DIC individually and in presence of coexistence risk further multiply. DIC scoring of every patient at risk as in pati... |
Understanding effects of DIC on organ dysfunction in septic shock patients can help to prognosticate and guide towards early intervention. Also, there is paucity of literature on effect of DIC score changes on organ dysfunction in patients with septic shock. conditions: Septic Shock conditions: Disseminated Intravascul... |
<|newrecord|> nctId: NCT06363136 id: 14.06.2023-111176 briefTitle: Foot Posture, Strength, Performance, and Postural Control in Isolated Gastrocnemius Tightness overallStatus: RECRUITING date: 2024-02-01 date: 2024-05-30 date: 2024-06-30 date: 2024-04-12 date: 2024-04-12 name: Bezmialem Vakif University class: OTHER br... |
In the literature, there is no study evaluating foot posture, muscle strength, functional performance, and postural control in children with isolated gastrocnemius muscle tightness. It was planned to evaluate postural control using computerized dynamic posturography (Biodex Balance System), lower extremity muscle stren... |
<|newrecord|> nctId: NCT06363123 id: BFHHZML20240009 briefTitle: Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis overallStatus: RECRUITING date: 2024-03-29 date: 2024-10 date: 2025-04 date: 2024-04-12 date: 2024-04-15 name: Beijing Friendship Hospital class: OTHER briefSummary: The aim of this observational stud... |
<|newrecord|> nctId: NCT06363110 id: 22724 briefTitle: An Observational Study to Learn More About Vericiguat Treatment Patterns and Its Safety in People With Chronic Heart Failure With Reduced Ejection Fraction in Routine Medical Care in the United States acronym: HOVER overallStatus: ACTIVE_NOT_RECRUITING date: 2024-0... |
In observational studies, only observations are made, without participants receiving any advice or any changes to healthcare. |
Chronic HFrEF is a long-term condition in which the heart becomes weak and cannot pump enough blood to the rest of the body with each heartbeat. This leads to a reduced supply of oxygen, which the body requires to function properly. |
The study treatment, vericiguat, works by increasing the activity of an enzyme called soluble guanylate cyclase (sGC), which relaxes the blood vessels and allows more blood to flow. As a result, the heart can pump better. |
It is already approved for doctors to prescribe to people with chronic HFrEF in the United States (US) who are stabilized after a recent "decompensation event". The treatment with vericiguat starts at a low dose, which should be increased gradually to the target dose based on how a patient tolerates the treatment. |
The participants in this study are already receiving treatment with vericiguat as part of their regular care from their doctors. |
The main purpose of the study is to learn more about the dosage pattern of vericiguat in people with chronic HFrEF in the US. To do this, researchers will collect the following information for 3 months after participants' first dose of vericiguat: |
* starting dose of vericiguat |
* daily changes in dosage pattern |
* time taken to reach the target dose |
* number and percentage of participants: |
* with specific changes in dosage pattern |
* reaching the target dose of vericiguat |
They will also collect information on how often low blood pressure or fainting occurs, which are well known events in people with chronic HFrEF. |
The data will come from the participants' information stored in a database called the HealthVerity HF dataset. Data collected will be from people with chronic HFrEF who started taking vericiguat between January 2021 and April 2023. |
Researchers will only look at the health records of participants in the US. |
Researchers will track participants' data and will collect information for a maximum of 6 months before and 3 months after their first dose of vericiguat. |
In this study, only available data from routine care are collected. No visits or tests are required as part of this study. conditions: Chronic Heart Failure With Reduced Ejection Fraction studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 1400 type: ESTIMATED name: Vericiguat (Ver... |
<|newrecord|> nctId: NCT06363097 id: ΔΔ5032 briefTitle: Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease overallStatus: RECRUITING date: 2023-09-04 date: 2024-12 date: 2025-06 date: 2024-04-12 date: 2024-04-12 name: Aristotle University Of Thessaloniki clas... |
<|newrecord|> nctId: NCT06363084 id: IST-Nim-PC-6 briefTitle: A Retrospective Study for Nimotuzumab Plus Postoperative Adjuvant Chemotherapy for Resectable Pancreatic Cancer overallStatus: COMPLETED date: 2016-05-01 date: 2022-07-31 date: 2023-06-30 date: 2024-04-12 date: 2024-04-12 name: Ruijin Hospital class: OTHER b... |
<|newrecord|> nctId: NCT06363071 id: 202000495A3 briefTitle: APA and PAS Training for Gait Initiation in Parkinson's Disease overallStatus: RECRUITING date: 2022-06-13 date: 2025-03-31 date: 2025-05-31 date: 2024-04-12 date: 2024-04-12 name: Chang Gung University class: OTHER briefSummary: Our research focused on under... |
<|newrecord|> nctId: NCT06363058 id: 201902166B0 briefTitle: Electrical Stimulation Cycling Training Effects on SCA overallStatus: RECRUITING date: 2022-04-08 date: 2025-07-31 date: 2025-07-31 date: 2024-04-12 date: 2024-04-17 name: Chang Gung University class: OTHER briefSummary: To focuses on the challenges faced by ... |
<|newrecord|> nctId: NCT06363045 id: NIDEK-TONOREF-UK-0001 briefTitle: Comparative Study of the NIDEK TONOREF III With Predicate Devices overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-11 date: 2024-11 date: 2024-04-12 date: 2024-04-17 name: Nidek Co. LTD. class: INDUSTRY briefSummary: The primary objective ... |
<|newrecord|> nctId: NCT06363032 id: 202110104RINB briefTitle: Elastography in Predicting Renal Outcome overallStatus: RECRUITING date: 2021-12-27 date: 2024-12-31 date: 2025-12-31 date: 2024-04-12 date: 2024-04-12 name: National Taiwan University Hospital class: OTHER briefSummary: There are two types of elastography:... |
Transthoracic shear-wave ultrasound is also used for the prediction of lung malignancy. |
In progressive renal disease, renal function decline correlates with the extent of interstitial fibrosis, irrespective of the original pathology. Experience and research in using shear-wave elastography to study the stiffness of renal parenchyma and renal fibrosis are scanty. The investigators will conduct a prospectiv... |
By assuming a power of 0.8, a two-side p value of 0.05, a ratio of 0.2 (sample sizes in negative/positive groups) to detect the difference between area under ROC curve and null hypothesis value (0.8 and 0.7), a target sample of 273 (with a 5% cushion, 260\~290) patients is required. conditions: Kidney Disease studyType... |
<|newrecord|> nctId: NCT06363019 id: 2023/00158 briefTitle: Supporting At-Risk Mothers Across Perinatal Period acronym: SMART overallStatus: RECRUITING date: 2024-02-26 date: 2025-02-26 date: 2026-07-06 date: 2024-04-12 date: 2024-04-12 name: National University of Singapore class: OTHER name: Ministry of Health, Singa... |
The goal of this interventional study is to test the effectiveness of a mobile-app health based intervention, SMART, mothers in the perinatal period. |
The main questions this study aims to answer are: |
1. What is the effect of a mobile-based health intervention, SMART, on maternal outcomes? |
2. What is the effect of a mobile-based health intervention, SMART, on infant outcomes? |
3. What is the cost-effectiveness of using SMART as compared to standard routine care? |
Researchers will compare results with a control group that will undergo standard routine care. conditions: Perinatal Depression conditions: Parents conditions: Anxiety conditions: Self Efficacy conditions: Stress conditions: Infant Development studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionMode... |
<|newrecord|> nctId: NCT06363006 id: K23C3280 briefTitle: Combination of Cardonizumab Injection and TKI Second Line Therapy for Advanced Hepatocellular Cancer overallStatus: RECRUITING date: 2024-03-11 date: 2026-01-01 date: 2027-01-01 date: 2024-04-12 date: 2024-04-12 name: Peking Union Medical College Hospital class:... |
* Objective response rate (ORR) for evaluation |
* Disease Control Rate (DCR); Duration of relief (DoR); Progression free survival (PFS); Total survival time (OS); Safety。 conditions: Hepatocellular Carcinoma studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: ... |
<|newrecord|> nctId: NCT06362993 id: STUDY00021561 briefTitle: Breast Cancer Screening in Ghana overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-11 date: 2025-03 date: 2024-04-12 date: 2024-04-15 name: Penn State University class: OTHER name: University of Ghana briefSummary: This study is designed to test th... |
<|newrecord|> nctId: NCT06362980 id: BPI-1178-IIT01 briefTitle: A Study With BPI-1178 and Osimertinib in Advanced Non-small Cell Lung Cancer Patients With EGFR Mutations acronym: EGFR overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2026-04-01 date: 2024-04-12 date: 2024-04-12 name: National Ca... |
<|newrecord|> nctId: NCT06362967 id: Anti-HLA antibody briefTitle: The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-31 date: 2026-06-30 date: 2024-04-12 date: 2024-04-12 name: Anhui P... |
<|newrecord|> nctId: NCT06362954 id: AnkaraMedipolU-FTR-SS-01 briefTitle: The Relationship Between Muscle Oxygenation and Spasticity in Hemiparetic Stroke Patients overallStatus: RECRUITING date: 2023-12-31 date: 2024-04-01 date: 2024-06-01 date: 2024-04-12 date: 2024-04-12 name: Ankara Medipol University class: OTHER ... |
This study aims to investigate the relationship between muscle oxygenation and spasticity in post-stroke hemiparetic patients based on the idea that oxygenation may be insufficient as a result of restriction of blood flow on the affected side due to spasticity in stroke patients. conditions: Stroke conditions: Hemipare... |
<|newrecord|> nctId: NCT06362941 id: NW-HGN-01 briefTitle: Evaluation of an Oral Hair Supplement to Improve Hair Strength and Support Growth in Women and Men overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-02-01 date: 2025-03-30 date: 2024-04-12 date: 2024-04-18 name: Nutraceutical Wellness Inc. class: IN... |
<|newrecord|> nctId: NCT06362928 id: CP-60005 briefTitle: Safety and Effectiveness of the Akura Thrombectomy System in the Treatment of Acute Pulmonary Embolism overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2025-06 date: 2025-08 date: 2024-04-12 date: 2024-04-12 name: Akura Medical class: INDUSTRY briefSummary:... |
<|newrecord|> nctId: NCT06362915 id: FMASUR66/2024 briefTitle: Analgesic Effect of Illiohypogastic & Ilioinguinal Nerve Block in TAVR - TF (Prospective Randomized Study) overallStatus: RECRUITING date: 2024-01-02 date: 2024-07-15 date: 2024-08-30 date: 2024-04-12 date: 2024-04-12 name: Ain Shams University class: OTHER... |
* Group (B): will receive ultrasound-guided ilioinguinal/iliohypogastric nerve block using 20 ml Bupivicane 0.25% by an experienced anesthesiologist. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 52 type: ESTIMATED name: Lidocaine name: Bupivacain measure: E... |
<|newrecord|> nctId: NCT06362902 id: NOSES-VIII B briefTitle: Laparoscopic Right Hemicolectomy With Transrectal Specimen Extraction for Colon Cancer overallStatus: RECRUITING date: 2024-03-01 date: 2025-09-01 date: 2025-09-01 date: 2024-04-12 date: 2024-04-12 name: National Cancer Center, China class: OTHER briefSummar... |
<|newrecord|> nctId: NCT06362889 id: HealMD-CBD-1 briefTitle: Evaluating Microneedling With CBD and Hempseed Oil for Acne Vulgaris Safety and Efficacy overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-10 date: 2024-11 date: 2024-04-12 date: 2024-04-12 name: Rejuva Medical Aesthetics class: OTHER name: HealMD, ... |
<|newrecord|> nctId: NCT06362876 id: BAlis briefTitle: The Effect of Breastfeeding Counseling Based on Motivational Interviewing overallStatus: ACTIVE_NOT_RECRUITING date: 2023-09-15 date: 2024-08-15 date: 2024-12-15 date: 2024-04-12 date: 2024-04-12 name: Mersin University class: OTHER briefSummary: This research was ... |
<|newrecord|> nctId: NCT06362863 id: WDRY2024-K027 briefTitle: Evaluation of Enteral Nutrition Biscuits for Inducing Remission in Moderate-to-severe Crohn's Disease overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-12 date: 2025-12 date: 2024-04-12 date: 2024-04-12 name: Ping An class: OTHER briefSummary: By c... |
<|newrecord|> nctId: NCT06362850 id: 1253/2023 briefTitle: Tele-Support for Emergency Medical Technicians acronym: POHCA overallStatus: RECRUITING date: 2024-04-08 date: 2024-04-18 date: 2024-12-01 date: 2024-04-12 date: 2024-04-12 name: Medical University of Vienna class: OTHER name: Ludwig Boltzmann Institute Digital... |
<|newrecord|> nctId: NCT06362837 id: P0117910-001 briefTitle: Evaluation of REACTS-IN, an Intervention to Improve Nutrition, Hygiene, and Sexual and Reproductive Health Services acronym: REACTS-IN overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2029-06-30 date: 2030-05-24 date: 2024-04-12 date: 2024-04-12 name... |
<|newrecord|> nctId: NCT06362824 id: 2094138 briefTitle: Promoting Physical Activity in Older Hispanic/Latino(a) Adults overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2028-09-30 date: 2029-09-30 date: 2024-04-12 date: 2024-04-15 name: Kaiser Permanente class: OTHER name: University of California, San Diego br... |
<|newrecord|> nctId: NCT06362811 id: 483730 briefTitle: Assessment of Efficacy of Sacral Erector Spinae Plane Block for Postoperative Analgesia in Pediatric Rectal Biopsies overallStatus: COMPLETED date: 2023-01-01 date: 2023-12-31 date: 2023-12-31 date: 2024-04-12 date: 2024-04-16 name: Istanbul University class: OTHE... |
<|newrecord|> nctId: NCT06362798 id: IRB22-0729 id: 1R01HD109293-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01HD109293-01 id: 6-23FY-0012 type: OTHER_GRANT domain: March of Dimes briefTitle: Effect of Support for Low-Income Mothers of Preterm Infants overallStatus: NOT_YET_RECRUITING date: 2024-05-01 dat... |
<|newrecord|> nctId: NCT06362785 id: Virtual Reality-Seniors briefTitle: Musculoskeletal Pain, Motor Control, Risk of Falls and Virtual Reality overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-06 date: 2026-06 date: 2024-04-12 date: 2024-04-12 name: Universidade da Coruña class: OTHER name: Centre for Informa... |
* What are the characteristics of a community-dwelling population over 60 years and older in terms of musculoskeletal pain, functionality, and risk of falls? |
* Does an intervention with virtual reality lower musculoskeletal pain, raise functionality and prevent falls in community-dwelling adults aged 60 years and older, compared to a control group that does not receive such intervention? |
Participants will: |
* Answer questionnaires. |
* Perform physical laboratory tests through a camera-based motion capture system. |
* Execute task-based exercises in a virtual environment through virtual reality. |
Researchers will compare community-dwelling adults aged 60 years and older who execute task based exercises in a virtual environment through virtual reality and community-dwelling adults aged 60 years and older without any intervention to see if virtual reality improves musculoskeletal pain, functionality, and lowers f... |
<|newrecord|> nctId: NCT06362772 id: MR-36-24-010944 briefTitle: Clinical Efficacy of 125I Seed Implantation in the Treatment of Refractory Differentiated Thyroid Cancer overallStatus: COMPLETED date: 2015-01-01 date: 2022-02-01 date: 2023-04-01 date: 2024-04-12 date: 2024-04-12 name: Jiangxi Provincial Cancer Hospital... |
<|newrecord|> nctId: NCT06362759 id: TOUR006-C01 briefTitle: A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP acronym: TRANQUILITY overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-05 date: 2026-02 date: 2024-04-12 date: 2024-04-12 name: Tourmaline Bio, Inc. class: INDUST... |
<|newrecord|> nctId: NCT06362746 id: FORPE-2 briefTitle: Non-immunogenic Recombinant Staphylokinase vs Placebo in Patients With Intermediate High-risk Pulmonary Embolism overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2028-06-01 date: 2028-12-01 date: 2024-04-12 date: 2024-04-12 name: Supergene, LLC class: IND... |
Non-immunogenic recombinant staphylokinase or placebo will be administered intravenously at a dose of 15 mg as a single bolus for 10-15 seconds. All patients will be examined for 30 days. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Neither patient nor investigator knows treatment assignment. All eligi... |
<|newrecord|> nctId: NCT06362733 id: IRB-74165 briefTitle: Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-06-01 date: 2026-06-01 date: 2024-04-12 date: 2024-04-12 name: Stanford University class: OTHER briefSummary: The purp... |
<|newrecord|> nctId: NCT06362720 id: 720/2566(IRB2) briefTitle: The Comparison the CMV Infection and Reactivation After Allogeneic Hematopoietic Stem Cell Transplantation Between Standard Regimen, Methotrexate Plus Cyclosporin A, and Post-transplant Cyclophosphamide-based Regimen acronym: CMV overallStatus: NOT_YET_REC... |
* How do CMV infection and reactivation differ between Allo-SCT patients who received a standard regimen versus those who received a Post-transplant Cyclophosphamide-based regimen? |
* progression-free survival, Median overall survival, cumulative incidence of relapse, non-relapsed mortality (NRM) and GvHD at 2 years after Allo-SCT |
* The impact of CMV infection and CMV reactivation on progression-free survival, overall survival, and NRM |
* Averse events of GVHD prophylaxis medication Participants will be collected the data of treatment and treatment response during transplant until 2 years after transplant from hospital medical record. conditions: CMV Infection or Reactivation After Allogenic HSCT studyType: OBSERVATIONAL observationalModel: CASE_ONLY ... |
<|newrecord|> nctId: NCT06362707 id: 2023161001 briefTitle: Fasudil Trial for Treatment of Early Alzheimer's Disease (FEAD) acronym: FEAD overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-10-01 date: 2026-10-01 date: 2024-04-12 date: 2024-04-15 name: Helse Stavanger HF class: OTHER_GOV name: University of E... |
The main questions it aims to answer are: |
* Does treatment with fasudil, a ROCK-inhibitor, lead to significant improvement in working memory (based on computer-based working memory composite scores) compared to placebo in individuals with early Alzheimer's disease (AD) over 12 months? |
* What is the effect of fasudil treatment for 12 months on other cognitive functions, brain metabolism measured by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET), and other relevant clinical functions and biomarkers in individuals with early Alzheimer's disease (AD)? |
* Treatment will be escalated to a maintenance dose of 120 mg total daily dose for up to 50 weeks, with regular clinic visits for efficacy and safety evaluations. |
* Assessments will include cognitive tests, FDG-PET scans, and biomarker analyses, with follow-up by the Data and Safety Monitoring Board for ongoing safety review. |
The study will compare participants receiving fasudil with those receiving placebo to see if fasudil treatment leads to improvements in cognitive functions, brain metabolism measured by FDG-PET. conditions: Cognitive Decline, Mild conditions: Alzheimer Disease studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOM... |
<|newrecord|> nctId: NCT06362694 id: 34 briefTitle: Study of the Rechallenge Concept in Patients With BRAF-positive Anaplastic Thyroid Cancer After Progression on Anti-BRAF Therapy overallStatus: RECRUITING date: 2024-03-25 date: 2026-03-25 date: 2026-06-25 date: 2024-04-12 date: 2024-04-12 name: Saint Petersburg State... |
<|newrecord|> nctId: NCT06362681 id: CF-2023-I-13 briefTitle: Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study overallStatus: RECRUITING date: 2024-03-01 date: 2024-06-30 date: 2026-03-30 date: 2024-04-12 date: 2024-04-12 name: Universidad Nacional Au... |
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