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<|newrecord|> nctId: NCT06355076 id: CSZ03 briefTitle: New Urethral Reconstruction in Robot-assisted Laparoscopic Radical Resection overallStatus: RECRUITING date: 2023-02-05 date: 2026-06 date: 2026-06 date: 2024-04-09 date: 2024-04-09 name: Qilu Hospital of Shandong University class: OTHER briefSummary: The purpose o... |
Is there a significant improvement in urinary control in patients with new reconstruction compared with patients with anastomosis? The researchers compared the new reconstruction with anastomosis in robot-assisted laparoscopic radical resection to see if the new reconstruction improved urinary incontinence after operat... |
Participants will: |
The intervention group adopted the new reconstruction proposed by our team; End-to-end anastomosis was performed in non-intervention group. conditions: Prostate Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The experimental group received a ... |
<|newrecord|> nctId: NCT06355063 id: NP-PCF-037 briefTitle: CellFX® nsPFA™ Cardiac Surgery System to Treat Atrial Fibrillation overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-08-31 date: 2025-10-31 date: 2024-04-09 date: 2024-04-09 name: Pulse Biosciences, Inc. class: INDUSTRY briefSummary: This feasibili... |
<|newrecord|> nctId: NCT06355050 id: UKJ-ultraHART briefTitle: Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer acronym: ultraHART overallStatus: NOT_YET_RECRUITING date: 2024-06-30 date: 2026-09-30 date: 2031-09-30 date: 2024-04-09 date: 2024-04-09 name: Jena University Hospital class: OTHER name: ... |
<|newrecord|> nctId: NCT06355037 id: B2024.1.30 briefTitle: Dasatinib Combined With Quercetin to Reverse Chemo Resistance in Triple Negative Breast Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2024-12-31 date: 2025-01-31 date: 2024-04-09 date: 2024-04-09 name: Fudan University class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06355024 id: A2024.1.30 briefTitle: Inosine Reverse Chemo Resistance in Triple Negative Breast Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2024-12-31 date: 2025-01-31 date: 2024-04-09 date: 2024-04-09 name: Fudan University class: OTHER briefSummary: This is a Phase II, open-... |
<|newrecord|> nctId: NCT06355011 id: 7016194 briefTitle: Total Elbow Replacement in England: Analysis of National Joint Registry and Hospital Episode Statistics Data overallStatus: COMPLETED date: 2024-03-01 date: 2024-04-02 date: 2024-04-02 date: 2024-04-09 date: 2024-04-09 name: University of Manchester class: OTHER ... |
* Who are receiving primary total elbow replacement surgery? |
* Where and by whom is the total elbow replacement surgery is being performed? |
* What the current surgical practices for total elbow replacement? |
Pseudonymous data from the National Joint Registry NJR of all patients with total elbow replacement will be used. conditions: Total Elbow Replacement studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 3891 type: ACTUAL name: Total Elbow Replacement measure: The incidence of total el... |
<|newrecord|> nctId: NCT06354998 id: mRNA-1273-P401 briefTitle: A Study of an Investigational mRNA-1273.815 COVID-19 Vaccine in Previously Vaccinated Adults overallStatus: RECRUITING date: 2024-04-08 date: 2024-06-01 date: 2024-06-01 date: 2024-04-09 date: 2024-04-22 name: ModernaTX, Inc. class: INDUSTRY briefSummary: ... |
<|newrecord|> nctId: NCT06354985 id: 23-5996 id: MODEX2023 type: OTHER domain: Clinical Trial Protocol Number id: FRN:183960 type: OTHER_GRANT domain: CIHR id: CTO Project ID: 4701 type: OTHER domain: Clinical Trials Ontario briefTitle: Modafinil and Exercise for Post Stroke Fatigue acronym: MODEX overallStatus: NOT_YE... |
Some studies have tested a drug called Modafinil for post stroke fatigue, while other studies have tested exercise for it. Yet, there is unclear evidence for either treatment, so this study has two main aims: |
1. Test if Exercise Program One is better than Exercise Program Two |
2. Test if Modafinil is better than a Sugar Pill |
As another aim, the investigators will also look at if combining Modafinil with exercise has any benefits. |
This study will take place at 6 Canadian research sites to give a good representation of people after a stroke. Each person will be tested on fatigue, mood, fitness, thinking skills, sleep, and usual activity levels. |
Participants will be assigned at random (like flipping a coin) to 1 of 4 groups: |
1. Sugar Pill plus Exercise Program One |
2. Sugar Pill plus Exercise Program Two |
3. Modafinil plus Exercise Program One |
4. Modafinil plus Exercise Program Two |
The treatment will last 8 weeks. The Modafinil or Sugar Pill will be taken once a day. The exercise will be delivered virtually by a trained therapist over computer to people at home 3 times a week. Change in fatigue, quality of life, and other outcomes will be measured over 6 months. |
The investigators will assess the results to identify the best treatment for post stroke fatigue and hope to be able to find a treatment that will help reduce fatigue and improve quality of life after a stroke. conditions: Stroke conditions: Fatigue conditions: Modafinil conditions: Exercise studyType: INTERVENTIONAL p... |
<|newrecord|> nctId: NCT06354972 id: SASP Turin briefTitle: Impact of SASP in the GCF on the Outcomes of Periodontal Regeneration overallStatus: COMPLETED date: 2022-01-02 date: 2022-11-02 date: 2024-01-02 date: 2024-04-09 date: 2024-04-09 name: University of Turin, Italy class: OTHER briefSummary: Objectives: To test ... |
Methods: Sites associated with intrabony defects ≥ 3 mm requiring periodontal regeneration through minimally-invasive surgical technique were included. Pre-operatively, GCF was sampled for inflammatory biomarker analysis related to SASP \[interleukin (IL)-1β, IL-6 and IL-12; matrix-metalloproteinases (MMP)-8 and -9\]. ... |
<|newrecord|> nctId: NCT06354959 id: 1030020 briefTitle: Prehab for Lung and Esophageal Cancer overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-06-01 date: 2027-01-01 date: 2024-04-09 date: 2024-04-09 name: Nova Scotia Health Authority class: OTHER name: Dalhousie University briefSummary: Research indicate... |
<|newrecord|> nctId: NCT06354946 id: SCORE 4C briefTitle: External Validation of Simplified 4C Mortality Score by Deleting CRP acronym: 4Cs overallStatus: COMPLETED date: 2020-01-01 date: 2022-11-30 date: 2022-12-30 date: 2024-04-09 date: 2024-04-09 name: University of Monastir class: OTHER briefSummary: The (Coronavir... |
<|newrecord|> nctId: NCT06354933 id: DemeNSS (3785) briefTitle: Neurological Soft Signs in Neurodegenerative Dementias acronym: DemeNSS overallStatus: COMPLETED date: 2022-04-01 date: 2023-11-30 date: 2024-02-01 date: 2024-04-09 date: 2024-04-15 name: University of Milano Bicocca class: OTHER briefSummary: The goal of ... |
* Does the prevalence of NSS significantly differ among patients with neurodegenerative dementias compared to controls? |
* Are NSS associated with neuropsychiatric alterations in dementia patients? |
* Do NSS correlate with cognitive screening tools? |
* Do NSS increase over time in patients with neurodegenerative dementias? |
Participants will undergo assessments including: |
* Evaluation of NSS using the Heidelberg scale |
* Neuropsychiatric assessments |
* Cognitive screening using the Mini-Mental State Examination (MMSE) and Frontal Assessment Battery (FAB) |
Researchers will compare dementia groups (Alzheimer's disease, Frontotemporal dementia, Corticobasal syndrome and Lewy body dementia) to controls to determine differences in NSS prevalence. Additionally, associations between NSS and neuropsychiatric symptoms, as well as cognitive performance, will be explored. conditio... |
<|newrecord|> nctId: NCT06354920 id: HUM00247781 id: R18HS028963 type: AHRQ link: https://reporter.nih.gov/quickSearch/R18HS028963 briefTitle: M-Well Bonding Bundle to Improve Patient-Physician Relationships overallStatus: RECRUITING date: 2024-04-08 date: 2026-06 date: 2026-06 date: 2024-04-09 date: 2024-04-10 name: U... |
* Will using the intervention strategies improve doctors' empathy towards their patients? |
* Will using the intervention strategies lead to improved scores in patient views of doctors' empathy? |
There will be 2 study arms. One group of doctors will be asked to use the intervention strategies. The other group of doctors will provide care as they would normally. |
Researchers will compare the doctors in the intervention arm to those in the control arm. |
Doctors are the primary subjects for this study. The doctors in both study arms will be asked to do the following: |
1. Allow study staff to observe the interaction between them and their patients. |
2. Complete a brief survey at the end of their 2-week work rotation. |
Doctors who are in the intervention arm will be asked to use suggested strategies when visiting with patients in the hospital. |
Patients are secondary subjects for this study. Patients of participating doctors may be asked to do the following: |
1. Allow study staff to observe the interaction between them and their doctors. |
2. Complete a brief survey after meeting with their doctor. conditions: Physician-Patient Relations studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Quasi-experimental randomized controlled trial primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE ... |
<|newrecord|> nctId: NCT06354907 id: HUM00150780 briefTitle: Improving Mental Health in School-age Children Through the Kids' Empowerment Program (KEP) acronym: KEP overallStatus: ACTIVE_NOT_RECRUITING date: 2022-10-03 date: 2024-10-02 date: 2024-10-02 date: 2024-04-09 date: 2024-04-12 name: University of Michigan clas... |
<|newrecord|> nctId: NCT06354894 id: MACOXS id: 133/2020/U type: REGISTRY domain: MACOXS briefTitle: Percutaneous Pinning Versus Plate and Screws for Surgical Fixation of Proximal Humeral Fractures overallStatus: RECRUITING date: 2020-11-01 date: 2024-11-01 date: 2024-11-01 date: 2024-04-09 date: 2024-04-09 name: Unive... |
<|newrecord|> nctId: NCT06354881 id: 0967 id: TM61008S3 type: OTHER_GRANT domain: British Heart Foundation briefTitle: The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke acronym: LACUNAR_CA overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-03 date: 2026-03 date: 2... |
<|newrecord|> nctId: NCT06354868 id: NNBioEP004 briefTitle: A Study to Assess utiLity of BIoEP as an Early Prognostic Indicator for Predicting Anti-Seizure Medication (ASM) Efficacy acronym: ECLIPSE overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-12 date: 2027-06 date: 2024-04-09 date: 2024-04-12 name: Neuro... |
<|newrecord|> nctId: NCT06354855 id: NEU-FTR-FE-04 briefTitle: "Which Type of Exercise is More Effective in Chronic Constipation? overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-15 date: 2024-10 date: 2024-12 date: 2024-04-09 date: 2024-04-09 name: Necmettin Erbakan University class: OTHER briefSummary: In this stud... |
<|newrecord|> nctId: NCT06354842 id: 12345678 briefTitle: Measurement of Sweat Sodium Concentration in Patients With Chronic Kidney Disease overallStatus: COMPLETED date: 2018-10-05 date: 2020-12-11 date: 2020-12-11 date: 2024-04-09 date: 2024-04-09 name: Medical University of Vienna class: OTHER briefSummary: It has b... |
In this cross-sectional feasibility study, we applied pilocarpine iontophoresis to induce sweat testing in 58 patients across various stages of CKD including patients after kidney transplantation as well as a healthy control cohort (n=6) to investigate possible effects of CKD and transplantation status on sweat rate an... |
Decline of kidney function showed a significant association with lower sweat rates: adj R²= 0.2278, F(2, 61) = 10.29, p = 0.000141. Sweat sodium concentrations were increased in moderate CKD, however this effect was lost in end stage renal disease: adj R² = 0.3701, F(4, 59) = 10.26, p = 2.261e-06. We observed higher sw... |
Diagnostic sweat analysis represents an innovative and promising noninvasive option for more thorough investigation of sodium- and fluid homeostasis in CKD patients. Lower sweat rates and higher sweat sodium concentrations represent a unique feature of CKD patients with potential therapeutic implications. conditions: C... |
<|newrecord|> nctId: NCT06354829 id: MEDICALBUM briefTitle: Medical Images Collection Research acronym: MEDICALBUM overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2049-04 date: 2049-04 date: 2024-04-09 date: 2024-04-09 name: Mario Negri Institute for Pharmacological Research class: OTHER name: Papa Giovanni XXIII... |
<|newrecord|> nctId: NCT06354816 id: V 2.0, 07Feb2024 briefTitle: VENLID: The Application of a 10%-Lidocaine Spray Prior to the Insertion of a Peripheral Intra-venous Catheter in Female Adults acronym: VENLID overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-05 date: 2024-05 date: 2024-04-09 date: 2024-04-09 n... |
<|newrecord|> nctId: NCT06354803 id: KafrelsheikhU 30 briefTitle: Effect of Pezzi Ball on Balance in Pregnant Women overallStatus: COMPLETED date: 2023-03-02 date: 2024-02-02 date: 2024-03-03 date: 2024-04-09 date: 2024-04-09 name: Kafrelsheikh University class: OTHER briefSummary: The effect of kinaesthetic training o... |
<|newrecord|> nctId: NCT06354790 id: NatHis LAMA2 briefTitle: Natural History Study of Children With LAMA2-related Dystrophies acronym: LAMA2 overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2027-06-14 date: 2027-12-31 date: 2024-04-09 date: 2024-04-09 name: Institut de Myologie, France class: OTHER name: Assoc... |
The aim of the study is to establish a well-described cohort of patients in France with LAMA2-RD for prospective follow-up and recruitment for future clinical trials. |
Participants will be follow up during a two years period regarding exhaustive aspects of the pathology: |
* Muscular function |
* Respiratory function |
* Cognitive phenotyping |
* Quality of life |
* Growth parameters |
* Biomarkers conditions: Merosin Deficient Congenital Muscular Dystrophy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: Motor evaluations name: Cognitive assessment name: Pulmonary function test name: Cardiac evaluation name: Quality of life name: Spine ... |
<|newrecord|> nctId: NCT06354777 id: EVERCOOL AF briefTitle: REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry acronym: EVERCOOL AF overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-11-30 date: 2024-12-30 date: 20... |
<|newrecord|> nctId: NCT06354764 id: 8780-UC1 briefTitle: Propensity to Hospitalize Patients From the ED in European Centers. acronym: eCREAM-UC1 overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2025-09 date: 2026-09 date: 2024-04-09 date: 2024-04-11 name: Mario Negri Institute for Pharmacological Research class: ... |
<|newrecord|> nctId: NCT06354751 id: 327236 briefTitle: Maternity Care Experiences of Asylum-seeking and Refugee Women in Scotland acronym: MACAWS overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-04-20 date: 2025-07-01 date: 2024-04-09 date: 2024-04-09 name: University of Aberdeen class: OTHER briefSummary... |
A scoping review was conducted to understand the experiences of asylum-seeking and refugee women accessing maternity care in the UK, with a focus on Scotland. The review found that all studies that focused on the experiences of asylum-seeking and refugee women accessing maternity care were mainly based in England. The ... |
This PhD aims to close this gap in research by exploring this area more deeply in Scotland through mixed-methods studies of surveys with asylum-seeking and refugee women and interviews with maternity care leaders, policymakers, maternity healthcare professionals, and asylum-seeking and refugee women. conditions: Refuge... |
<|newrecord|> nctId: NCT06354738 id: S66928 briefTitle: Improving Endometrial Cancer Assessment by Combining Genomic Profiling and Surgical Assessment acronym: EUGENIE overallStatus: RECRUITING date: 2023-01-16 date: 2028-11-01 date: 2028-11-01 date: 2024-04-09 date: 2024-04-17 name: University Hospital, Gasthuisberg c... |
<|newrecord|> nctId: NCT06354725 id: 2vs4 briefTitle: Effect of Weekly Plyometric Training Frequency on Youth Female Basketball Players: A Comparison of Two vs. Four Sessions overallStatus: COMPLETED date: 2023-11-01 date: 2024-01-20 date: 2024-02-20 date: 2024-04-09 date: 2024-04-09 name: Bruno Figueira class: OTHER n... |
<|newrecord|> nctId: NCT06354712 id: 2024-45 briefTitle: Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients. overallStatus: RECRUITING date: 2024-04-04 date: 2025-03-01 date: 2025-03-01 date: 2024-04-09 date: 2024-04-09 name: Mansoura University class: OTHER ... |
<|newrecord|> nctId: NCT06354699 id: RGS0000003993 briefTitle: A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children acronym: POPSICLE overallStatus: RECRUITING date: 2023-06-26 date: 2028-06 date: 2028-07 date: 2024-04-09 date: 2024-04-09 name: Teletho... |
<|newrecord|> nctId: NCT06354686 id: STUDY00004245 briefTitle: Characterizing the Scalp Tolerability of TMS overallStatus: RECRUITING date: 2024-02-12 date: 2026-05 date: 2027-05 date: 2024-04-09 date: 2024-04-09 name: Florida State University class: OTHER briefSummary: The primary objective is to characterize the tole... |
<|newrecord|> nctId: NCT06354673 id: 278/1-April-2024 briefTitle: Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm. overallStatus: ENROLLING_BY_INVITATION date: 2024-04-04 date: 2024-09-04 date: 2024-10-04 date: 2024-04-09 date: 2024-04-10 name: Zagazi... |
<|newrecord|> nctId: NCT06354660 id: 18804 id: J1I-MC-GZBY type: OTHER domain: Eli Lilly and Company briefTitle: Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1) overallStatus: NOT_YET_RECRUITING date: 2... |
<|newrecord|> nctId: NCT06354647 id: HM20028419 briefTitle: Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-05-01 date: 2027-06-01 date: 2024-04-09 date: 2024-04-09 name: Virginia Commonwealth University class: ... |
<|newrecord|> nctId: NCT06354634 id: HM20028439 briefTitle: Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-07 date: 2027-07 date: 2024-04-09 date: 2024-04-09 name: Virginia Commonwealth Univers... |
<|newrecord|> nctId: NCT06354621 id: D/185/FIMS briefTitle: Impact of Vitamin D Supplementation on Fetomaternal Outcomes in LTBI Pregnant Females acronym: RCT overallStatus: COMPLETED date: 2023-09-01 date: 2024-02-28 date: 2024-03-20 date: 2024-04-09 date: 2024-04-09 name: University of the Punjab class: OTHER briefSu... |
The main question\[s\] it aims to answer are: |
If Vitamin D supplementation has any impact on maternal outcomes. If Vitamin D supplementation has any impact on fetal outcomes. conditions: Maternal and Child Health studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: QUADR... |
<|newrecord|> nctId: NCT06354608 id: duygudemirr briefTitle: The Effect of Audio Book and Local Vibration on Pain and Fear in Intramuscular Injection in Children overallStatus: RECRUITING date: 2023-10-25 date: 2024-04-01 date: 2024-04-30 date: 2024-04-09 date: 2024-04-09 name: University of Yalova class: OTHER briefSu... |
<|newrecord|> nctId: NCT06354595 id: XiamenU1 briefTitle: Feasibility Study of Multidimensional Rehabilitation in the Metaverse overallStatus: RECRUITING date: 2024-03-01 date: 2024-04-30 date: 2024-05-01 date: 2024-04-09 date: 2024-04-09 name: Qu Shen class: OTHER name: The First Affiliated Hospital of Xiamen Universi... |
<|newrecord|> nctId: NCT06354582 id: 2024-085-01 briefTitle: Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia acronym: EIVCIMFAELA overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-01 date: 2025-02 date: 2024-04-09 date: 2024-04-09 name: Kunyue Li class: OTHER name: ... |
<|newrecord|> nctId: NCT06354569 id: 2022.232 briefTitle: Risk Factors and Risk Grading Prediction of Perioperative Respiratory Adverse Events in Children overallStatus: RECRUITING date: 2024-12-31 date: 2024-12-31 date: 2024-12-31 date: 2024-04-09 date: 2024-04-09 name: Sichuan Provincial People's Hospital class: OTHE... |
<|newrecord|> nctId: NCT06354556 id: HRS-1893-102 briefTitle: Effect of Verapamil Tablets on the Pharmacokinetic of HRS-1893 Tablets in Healthy Subjects overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-05-05 date: 2024-05-30 date: 2024-04-09 date: 2024-04-09 name: Shandong Suncadia Medicine Co., Ltd. class... |
<|newrecord|> nctId: NCT06354543 id: CA01-TK-ARTHRO briefTitle: Arthroplasty Cements Outcomes - A Post-market Follow-up overallStatus: RECRUITING date: 2020-12-16 date: 2035-12 date: 2045-12 date: 2024-04-09 date: 2024-04-09 name: Teknimed class: INDUSTRY briefSummary: A Post-Market Clinical Follow-Up (PMCF) Study to c... |
Teknimed bone cements and cement restrictor are legacy products, some marketed for more than 20 years. Their performance and safety have already been demonstrated by Post-Market Surveillance and previous clinical studies. The current Post-Market Clinical Follow-Up study aims to confirm these claims by collecting data i... |
The study is a retrospective and prospective global, single arm, non-controlled, multicentric, ambispective observational study. Patients will be followed as per local standard medical care of the site. conditions: Arthroplasty studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 1050 type:... |
<|newrecord|> nctId: NCT06354530 id: 2023 (315) briefTitle: A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma overallStatus: RECRUITING date: 2024-03-08 date: 2025-12-31 date: 2026-12-31 date: 2024-04-09 date: 2024-04-09 name: Army Medical Center of PL... |
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