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* Do raspberry leaf polyphenols lower sucrose-induced increases in plasma glucose in humans? |
* Do these polyphenols mediate these effects by inhibiting digestion of sucrose or the absorption of glucose. |
20 healthy adults will be recruited between the ages of 18-65 years who are non-smokers and not taking certain types of medication (e.g., drugs from a GP for high blood pressure, high blood fats, inflammatory conditions, and depression) or dietary supplements (e.g., cholesterol-lowering spreads, fish oil, probiotics, p... |
They will be asked to attend a four-study visit after an eight-hour overnight fast. Volunteers will be asked to consume 50 g of carbohydrate powder (sucrose and glucose) with or without 10 g of raspberry leaf tea, which will be dissolved in 300 mL of warm water during four visits (every month). Blood samples will be ta... |
<|newrecord|> nctId: NCT06385613 id: TDK-2024-13377 briefTitle: The Effect of Mobile-Based Education on Self-Care, Quality of Life and Complications in Patients With Intestinal Stoma overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2025-04-22 date: 2025-08-22 date: 2024-04-26 date: 2024-04-26 name: Ataturk Univ... |
<|newrecord|> nctId: NCT06385600 id: severe preeclampsia briefTitle: Intravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia. overallStatus: NOT_YET_RECRUITING date: 2024-05-20 date: 2026-01-20 date: 2026-03-20 date: 2024-04-26 date: 2024-04-26 name: Assiut University class: OTHER briefSummary: ... |
<|newrecord|> nctId: NCT06385587 id: ADH-OL-Study-01-23 briefTitle: Technology-based Symptom Monitoring Intervention for Locally Advanced Head and Neck Cancer Patients acronym: SYMTECH01 overallStatus: NOT_YET_RECRUITING date: 2024-05-03 date: 2024-12-29 date: 2025-09-27 date: 2024-04-26 date: 2024-04-29 name: Aptar Di... |
<|newrecord|> nctId: NCT06385574 id: 2023-088 briefTitle: Technological Based Rehabilitation on Individuals With Rheumatic Disease overallStatus: RECRUITING date: 2024-03-15 date: 2024-05-15 date: 2024-05-20 date: 2024-04-26 date: 2024-04-26 name: Akdeniz University class: OTHER briefSummary: Affects such as pain, swel... |
<|newrecord|> nctId: NCT06385561 id: Tramadol_OIBD id: 2022-500108-23-00 type: CTIS briefTitle: The Influence of Tramadol on Opioid-induced Bowel Dysfunction overallStatus: COMPLETED date: 2022-08-11 date: 2023-05-15 date: 2023-05-15 date: 2024-04-26 date: 2024-04-26 name: Asbjørn Mohr Drewes class: OTHER briefSummary:... |
<|newrecord|> nctId: NCT06385548 id: VHIO21001 briefTitle: Efficacy and Safety Study of Lurbinectedin and Dostarlimab in Cancer Patients: Protocol VHIO21001 - LiDer acronym: LiDer overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-04 date: 2026-04 date: 2024-04-26 date: 2024-04-26 name: Vall d'Hebron Institute ... |
Endometrial cancer is a prevalent gynecological malignancy, with a significant number of cases diagnosed at an advanced stage or recurring following initial treatment. Platinum-based chemotherapy represents a standard treatment option for these patients; however, disease progression often occurs, highlighting the need ... |
Primary Objectives: |
To determine the maximum tolerated dose (MTD) and recommended dose for further investigation of lurbinectedin and dostarlimab in combination therapy for advanced or recurrent endometrial cancer. |
To assess the antitumor activity of lurbinectedin and dostarlimab combination therapy, measured by objective response rate (ORR), in patients with advanced or recurrent endometrial cancer. |
Secondary Objectives: |
To evaluate the safety and tolerability of lurbinectedin and dostarlimab combination therapy in patients with advanced or recurrent endometrial cancer. |
To characterize the pharmacokinetic profile of lurbinectedin and dostarlimab when administered in combination therapy. |
To explore pharmacogenomic biomarkers predictive of response and/or resistance to lurbinectedin and dostarlimab combination therapy in patients with advanced or recurrent endometrial cancer. |
To assess progression-free survival (PFS), duration of response (DOR), clinical benefit rate (CBR), and overall survival (OS) in patients receiving lurbinectedin and dostarlimab combination therapy for advanced or recurrent endometrial cancer. |
To investigate the impact of lurbinectedin and dostarlimab combination therapy on quality of life and symptom control in patients with advanced or recurrent endometrial cancer. conditions: Endometrial Cancer studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPu... |
<|newrecord|> nctId: NCT06385535 id: IRB_00171031 briefTitle: Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder acronym: PTD overallStatus: RECRUITING date: 2024-04-04 date: 2024-12 date: 2024-12 date: 2024-04-26 date: 2024-04-26 name: University of Utah class: OTHER briefSu... |
1. See whether a tic's timing is related to other characteristics of the tic, like how long it has been happening and how well the person can control/stop that tic |
2. See whether the timing of a tic can tell us how well the person can control/stop that tic |
3. See whether tic treatment changes the timing of tics, and if the timing of a tic has anything to do with how well treatment will work to stop it |
Participants will meet with a study researcher to learn more about the study, ask questions, and decide whether or not they would like to be involved. If they decide to do the study, they will meet with the researcher 6 times: |
1. During the first visit, the study researcher will ask questions about the participant's life, tics, and other psychological symptoms. The researcher will watch the participant's tics for 10 minutes. The participant will do a computer task where they follow instructions to tic or not tic. |
2. During the second visit, the study researcher will treat one of the participant's tics. |
3. During the third visit, the study researcher will treat another one of the participant's tics. |
4. During the fourth visit, the study researcher will treat another one of the participant's tics. |
5. During the fifth visit, the study researcher will treat another one of the participant's tics. |
6. During the sixth visit, the study researcher will ask questions about the participant's tics and other psychological symptoms. The participant will do a computer task where they follow instructions to tic or not tic. conditions: Tics conditions: Tic Disorders conditions: Vocal Tic conditions: Motor Tic conditions: T... |
<|newrecord|> nctId: NCT06385522 id: BITR2101-C-01 briefTitle: A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphom... |
<|newrecord|> nctId: NCT06385509 id: TOL-CLAR-20024 briefTitle: A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-10 date: 2026-02 date: 2024-04-26 date: 2024-04-26 name: Tolmar Inc. class: INDUSTRY name: ICON p... |
<|newrecord|> nctId: NCT06385496 id: NCI-2024-01145 id: NCI-2024-01145 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: EAY131-L id: EAY131-L type: OTHER domain: ECOG-ACRIN Cancer Research Group id: EAY131-L type: OTHER domain: CTEP id: U10CA180820 type: NIH link: https://reporter.nih.gov/quickSearch/... |
<|newrecord|> nctId: NCT06385483 id: NCI-2024-01125 id: NCI-2024-01125 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: EAY131-A type: OTHER domain: ECOG-ACRIN Cancer Research Group id: EAY131-A type: OTHER domain: CTEP id: U10CA180820 type: NIH link: https://reporter.nih.gov/quickSearch/U10CA180820 b... |
<|newrecord|> nctId: NCT06385470 id: HSEARS20231112001 briefTitle: Treatment of Cantonese Speakers With Childhood Apraxia of Speech overallStatus: RECRUITING date: 2024-04-15 date: 2024-08-01 date: 2025-02-01 date: 2024-04-26 date: 2024-04-26 name: The Hong Kong Polytechnic University class: OTHER name: University of V... |
<|newrecord|> nctId: NCT06385457 id: 24-2933 briefTitle: The Effects of Mindhelper on Young People's Well-being, Psychological Functioning, and Intentions to Help-seeking overallStatus: NOT_YET_RECRUITING date: 2024-04-29 date: 2025-01-31 date: 2025-01-31 date: 2024-04-26 date: 2024-04-26 name: University of Southern D... |
A minimum of 9,426 young people aged 15 to 25 will be recruited through social media and invited to participate in the study. When responding to the baseline questionnaire participants will be randomized to either the intervention or control group. The intervention group will receive information about Mindhelper.dk and... |
Three follow-up questionnaires will then be sent to the participants 2 weeks, 6 weeks and 12 weeks after randomization. |
The investigators expect a small, positive effect on participants well-being and psychological functioning in intervention groups as compared to the control group. conditions: Mental Health Issue conditions: Well-Being conditions: Adolescents conditions: Young Adults conditions: Online Intervention conditions: Internet... |
Young people will be recruited through social medias. When responding to the baseline questionnaire participants will be randomized to either the intervention or control group. |
The intervention group will receive information about Mindhelper.dk and inspiration on how to use Mindhelper through text-messages during the study period. The control group does not receive information about Mindhelper.dk, until after completion of the last follow-up questionnaire. |
Three follow-up questionnaires will then be sent to the participants 2 weeks, 6 weeks and 12 weeks after randomization. primaryPurpose: OTHER masking: SINGLE maskingDescription: The participants are partly masked. The control group will be masked; however, the intervention group will not be masked. |
There is no care provider nor outcome assessor as all measures are self-reported and collected through online questionnaires. |
Analyses of data and interpretation of results will be done masked. whoMasked: INVESTIGATOR count: 9426 type: ESTIMATED name: Mindhelper- A national youth mental health promotion website measure: General well-being measure by "The Well-Being Index WHO-5" (WHO5) measure: Psychological functioning, measure by "The Short ... |
<|newrecord|> nctId: NCT06385444 id: 2024-HS-020 briefTitle: IVF Failure and Pregnancy Loss on Couples' Psychological Stress overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-06-01 date: 2024-04-26 date: 2024-04-26 name: The First Hospital of Jilin University class: OTHER briefSummary: The ... |
What are the psychological effects of IVF implantation failure and IVF pregnancy loss on women and the psychological differences between couples? Participants already taking IVF as part of their regular medical care will answer online survey questions about their joint pain for 1 years. conditions: Fertilization in Vit... |
<|newrecord|> nctId: NCT06385431 id: Charm briefTitle: Obeservational Cohort for Evaluating Future Cardiovascular Disease With High Metabolic Risks acronym: Charm overallStatus: NOT_YET_RECRUITING date: 2024-04-28 date: 2026-04-30 date: 2026-04-30 date: 2024-04-26 date: 2024-04-26 name: The First Affiliated Hospital wi... |
In recent years, the new concept of cardiovascular and metabolic diseases has been actively promoted at home and abroad, and the focus of prevention and treatment strategy of cardiovascular and metabolic diseases has been called for.The project proposed the concept of co-treatment of metabolic diseases based on disorde... |
<|newrecord|> nctId: NCT06385418 id: WST-CRC-202404 briefTitle: Fluorouracil Treatment Via Colon for Colorectal Cancer overallStatus: RECRUITING date: 2024-05-01 date: 2028-05-01 date: 2029-05-01 date: 2024-04-26 date: 2024-04-26 name: The Second Hospital of Nanjing Medical University class: OTHER briefSummary: Fluorou... |
<|newrecord|> nctId: NCT06385405 id: 2024y0423 briefTitle: Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation Treatment overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2026-05 date: 2024-04-26 date: 2024-04-26 name: Shanghai Mental Health Center class: OTHER name: Nati... |
<|newrecord|> nctId: NCT06385392 id: A23-354 briefTitle: Continuous Wearable Monitor for the Detection and Release of Freezing of Gait. overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-26 date: 2024-04-26 name: HealthPartners Institute class: OTHER briefSummary: The proposed sys... |
<|newrecord|> nctId: NCT06385379 id: WQ21-2301 briefTitle: Guo's Aortic Arch Reconstruction: A Multicenter, Prospective Study of the Novel WeFlow-Tribranch System (GENIUS Study) overallStatus: RECRUITING date: 2024-04-30 date: 2025-12-31 date: 2030-12-31 date: 2024-04-26 date: 2024-04-26 name: Hangzhou Endonom Medtech ... |
<|newrecord|> nctId: NCT06385366 id: GS_NP1 briefTitle: Developing & Evaluating Models for Early Predicting Obstetrical Diseases in Pregnant Women by Non-invasive Prenatal Test overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-05-06 date: 2025-06-06 date: 2024-04-26 date: 2024-04-26 name: Gene Solutions cla... |
<|newrecord|> nctId: NCT06385353 id: 2022-CHITS-003 id: 2023-A02652-43 type: OTHER domain: ID-RCB number briefTitle: DVT Burden and the Risk of Post-thrombotic Syndrome acronym: DVT-Burden overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-06 date: 2026-06 date: 2024-04-26 date: 2024-04-26 name: Centre Hospital... |
Prognostic tools for predicting risk are very useful for choosing the optimum treatment and improving patient management and are a preliminary step before developing predictive models useful for determining sensitivity to treatment. At present, although several prognostic markers and models have been proposed, it is st... |
The Venous Volumetric Index or VVI (Ouriel 1999) will be used for quantifying DVT-Burden. The VVI was constructed by calculating the volume from the diameter and length of 14 venous segments from the calf veins to the inferior vena cava. The VVI has been validated for its ability to discriminate between symptomatic and... |
This study aim to assess the performance of baseline DVT-burden estimated by the VVI score on ultrasound for predicting the occurrence and the severity of PTS as assessed by the Villalta scale at 6 months. conditions: Postthrombotic Syndrome studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_... |
<|newrecord|> nctId: NCT06385340 id: CentroDerm_LRP22003 briefTitle: Investigation of the Effect of Lipikar Baume AP+M overallStatus: NOT_YET_RECRUITING date: 2024-04-23 date: 2024-09-30 date: 2024-10-31 date: 2024-04-26 date: 2024-04-26 name: CentroDerm GmbH class: NETWORK briefSummary: Application of Lipikar Baume AP... |
It's a randomized, evaluator blinded, intra-individual controlled study conducted in one center in Germany, in adult subjects having AK (grade I to III) lesions on the forearms and back of hands and meeting specific inclusion/exclusion criteria. |
A total of 20 subjects will be enrolled. |
The study design consists in 4-week evaluation period, with 2 visits per subject: Screening/Baseline (Day 0, Day 28 (end of Lipikar Baume AP+M application)). conditions: Actinic Keratoses studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: It's a randomi... |
<|newrecord|> nctId: NCT06385327 id: ABI-5366-101 briefTitle: A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-07 date: 2025-07 date:... |
<|newrecord|> nctId: NCT06385314 id: Degirmenci1499 briefTitle: A Cross Sectional Study on Dental Anxiety and State Anxiety Related to Removal of Fixed Partial Dentures overallStatus: COMPLETED date: 2022-09-05 date: 2023-11-25 date: 2023-12-29 date: 2024-04-26 date: 2024-04-26 name: Abant Izzet Baysal University class... |
<|newrecord|> nctId: NCT06385301 id: Lung_disease_6MWD_SOT briefTitle: Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy With Chronic Lung Diseases overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-11 date: 2024-04-26 date: 2024-04-26 name: University of Zurich class: OTHER briefSum... |
<|newrecord|> nctId: NCT06385288 id: 268/2021BO2 briefTitle: Blood and Tissue Extraction for Immunological Examinations During Neoadjuvant Therapy of Soft Tissue Sarcomas overallStatus: RECRUITING date: 2021-07-21 date: 2026-07-21 date: 2031-07-21 date: 2024-04-26 date: 2024-04-26 name: University Hospital Tuebingen cl... |
<|newrecord|> nctId: NCT06385275 id: H-44897 briefTitle: The Role of Vitamin K on Knee Osteoarthritis Outcomes overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2026-12 date: 2026-12 date: 2024-04-26 date: 2024-04-26 name: Boston University class: OTHER name: National Institute of Arthritis and Musculoskeletal and ... |
The overall goal of this pilot randomized clinical trial (RCT) is to test different subtypes and doses of vitamin K supplementation in older adults with knee OA and to measure changes in relevant biochemical measures. conditions: Osteo Arthritis Knee studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED intervent... |
<|newrecord|> nctId: NCT06385262 id: Pro00114645 briefTitle: TOP 2301: Neoadjuvant Chemo for NSCLC overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-06-30 date: 2028-06-30 date: 2024-04-26 date: 2024-04-29 name: Duke University class: OTHER name: Regeneron Pharmaceuticals briefSummary: In this open-label, t... |
Eligible patients will be randomized with equal allocation to two treatment groups. Permuted block randomization algorithm will be used for treatment assignment with stratification factors: stage (1B, 2A, 2B, 3A), and performance status (0 vs. 1). |
The study hypothesis is that the addition of alirocumab to neoadjuvant chemoimmunotherapy will make tumor cells more immunogenic to cytotoxic T cells, resulting in an increase in complete pathologic responses in surgically resected tumor. conditions: Non Small Cell Lung Cancer studyType: INTERVENTIONAL phases: PHASE2 a... |
<|newrecord|> nctId: NCT06385249 id: NAV-0012 briefTitle: An Evaluation of Navina Mini, a New Trans-anal Irrigation (TAI) Device in Children and Adolescents overallStatus: RECRUITING date: 2024-04-03 date: 2024-10 date: 2024-12 date: 2024-04-26 date: 2024-04-26 name: Wellspect HealthCare class: INDUSTRY briefSummary: T... |
<|newrecord|> nctId: NCT06385236 id: 804913 id: R01HL161362 type: NIH link: https://reporter.nih.gov/quickSearch/R01HL161362 briefTitle: Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping acronym: EPIPHANY overallStatus: RECRUITING date: 2024-02-19 date: 2027-06-30 date: 2028-01-31 date: 20... |
By evaluating response to 2 different biologic therapies, this study has the potential to provide an in-depth understanding of the mechanisms underlying severe asthma that will inform and change treatment decisions, and may ultimately lead to a change in the way that asthma patients are evaluated for potential personal... |
<|newrecord|> nctId: NCT06385223 id: DSRB 2023/00680 briefTitle: A Novel Individualized Connectome-guided Approach for Precision Intermittent Theta Burst Stimulation for Depression overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-07-01 date: 2026-12-31 date: 2024-04-25 date: 2024-04-25 name: Institute of M... |
<|newrecord|> nctId: NCT06385210 id: 22SM7855 briefTitle: Barriers to Routine Surgical Video Recording overallStatus: COMPLETED date: 2024-04-01 date: 2024-04-24 date: 2024-04-24 date: 2024-04-25 date: 2024-04-26 name: Imperial College London class: OTHER briefSummary: In order to improve the implementation of routine ... |
<|newrecord|> nctId: NCT06385197 id: 170886-HMO-CTIL briefTitle: Improving the Effect of Multiple Sclerosis Drugs by Chronobiology overallStatus: COMPLETED date: 2022-05-08 date: 2023-06-01 date: 2023-06-02 date: 2024-04-25 date: 2024-04-25 name: Hadassah Medical Organization class: OTHER briefSummary: A trial for eval... |
<|newrecord|> nctId: NCT06385184 id: NCR234859 briefTitle: Social & QoL Behaviors in Parkinson's Disease overallStatus: RECRUITING date: 2024-03-08 date: 2025-12-31 date: 2025-12-31 date: 2024-04-25 date: 2024-04-25 name: Gregory Wallace class: OTHER briefSummary: Adults with Parkinson's Disease experience an array of ... |
<|newrecord|> nctId: NCT06385171 id: FFA-BTX-1 briefTitle: Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-08-01 date: 2027-01-05 date: 2024-04-25 date: 2024-04-25 name: Global Aesthetics LLC class: O... |
<|newrecord|> nctId: NCT06385158 id: GenSci074-101 briefTitle: A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population overallStat... |
<|newrecord|> nctId: NCT06385145 id: GenSci004-107 briefTitle: A Bioavailability Study of Two Different PEG-rhGH Preparations. overallStatus: NOT_YET_RECRUITING date: 2024-05-08 date: 2024-07-13 date: 2024-12-26 date: 2024-04-25 date: 2024-04-25 name: Changchun GeneScience Pharmaceutical Co., Ltd. class: INDUSTRY brief... |
<|newrecord|> nctId: NCT06385132 id: 6447 briefTitle: Psychological and Psychiatric prOfile in Glioblastoma and Head and Neck Cancer acronym: APPOINT overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-04-30 date: 2025-10-31 date: 2024-04-25 date: 2024-04-25 name: Fondazione Policlinico Universitario Agostino... |
Patients with head and neck cancer (H\&N-C) and Glioblastoma multiforme (GBM) have high psychological and sometimes psychiatric comorbidity probably due to the severity, poor prognosis of these cancers and harsh treatment toxicities. |
The most important protective factor for psychopathology is psychological resilience, which is "the capacity of a person to protect themselves and their mental health when facing life adversities," such as a GBM or H\&N-C diagnosis. Resilience is influenced by the affective temperament, which refers to basic personalit... |
To date, the literature does not clarify the role of resilience and temperament in mediating the psychological profile of cancer patients. Furthermore, extensive profiling of the psychological and psychiatric profile of these patients at such a critical and pivotal moment in their journey is currently lacking in the li... |
Aim of this study is to evaluate global psychological and psychiatric profile of patients affected by GBM and H\&N-C and the eventual fluctuation over time during RT course. Conducting an early and accurate screening for potential psychopathological issues will give the opportunity to avoid factors that could: worsen p... |
The results obtained will be utilized for planning precocious psychological or psychiatric take-in-charge aimed at promoting psychological well-being of H\&N-C and GBM patients. conditions: Glioblastoma conditions: Head and Neck Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE cou... |
<|newrecord|> nctId: NCT06385119 id: F8394-101 briefTitle: A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Volunteers. overallStatus: NOT_YET_RECRUITING date: 2024-04-24 date: 2024-10-31 date: 2024-11-25 date: 2024-04-25 date: 2024-04-25 name: Fore Biotherapeutics class: INDUST... |
* The effect of food on the single dose PK of plixorafenib administered with cobicistat. |
* The effect of cobicistat administration on the single dose PK of plixorafenib. |
* The safety of plixorafenib administered alone and with cobicistat in a single dose regimen in healthy participants. conditions: Healthy Volunteer studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: NONE count: 12 type: ESTIMATED name: Pli... |
<|newrecord|> nctId: NCT06385106 id: rTMS in AD briefTitle: Effects of Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2025-01 date: 2024-04-25 date: 2024-04-25 name: First Affiliated Hospital of Zhejiang University cl... |
<|newrecord|> nctId: NCT06385093 id: EDR-IIS-003 briefTitle: A Study on the Prevention and Treatment of GIOP With Eldecalcitol acronym: ELEGANT overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-12 date: 2026-03 date: 2024-04-25 date: 2024-04-25 name: Chinese SLE Treatment And Research Group class: OTHER name: ... |
<|newrecord|> nctId: NCT06385080 id: 61186372HNC2002 briefTitle: A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Recurrent/Metastatic Head and Neck Cancer acronym: OrigAMI-4 overallStatus: RECRUITING date: 2024-04-22 date: 2026-07-17 date: 2026-07-17 date: 2024-04-25 date: 202... |
<|newrecord|> nctId: NCT06385067 id: JW-PM-DCB-2024 briefTitle: Treatment of Primary Coronary Artery Vascular Lesions With Biolimus Coated Coronary Balloon Dilation Catheter overallStatus: NOT_YET_RECRUITING date: 2024-05-10 date: 2025-12-30 date: 2026-12-30 date: 2024-04-25 date: 2024-04-25 name: JW Medical Systems Lt... |
The study population was patients with primary coronary vascular lesions with a blood vessel diameter of 2.0mm-2.75mm. conditions: Coronary Artery Disease studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 400 type: ESTIMATED name: Biolimus Coated Coronary Artery Balloon Dilation... |
<|newrecord|> nctId: NCT06385054 id: L-027 id: 2023-A02612-43 type: REGISTRY domain: ID-RCB id: PEC23063 type: OTHER domain: Biofortis briefTitle: Effect of Probiotics on Infantile Colic Symptoms acronym: EPIC overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-02 date: 2027-02 date: 2024-04-25 date: 2024-04-29 ... |
<|newrecord|> nctId: NCT06385041 id: BE-2-83 briefTitle: Cardiac Rehabilitation and Frailty Physical Training Program in Elderly Patients After Open Heart Surgery overallStatus: RECRUITING date: 2021-05-12 date: 2025-09-01 date: 2025-09-01 date: 2024-04-25 date: 2024-04-25 name: Vitalija Stonkuvienė class: OTHER briefS... |
<|newrecord|> nctId: NCT06385028 id: 20230213_PIANISSIMO briefTitle: Physical Activity Promotion in Osteoarthritis Patients acronym: PIANISSIMO overallStatus: NOT_YET_RECRUITING date: 2024-10-01 date: 2026-03-31 date: 2026-12-31 date: 2024-04-25 date: 2024-04-25 name: Luxembourg Institute of Health class: OTHER_GOV nam... |
A mobile phone application - namely PIANISSIMO - will be developed specifically for this project. It aims to spread knowledge on the benefits of physical activity and collect data on how this knowledge can induce behavior changes toward a more physically active lifestyle. |
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