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* Phase 1: What does physical activity (intensity) mean to people with COPD?
* Phase 2: Are there differences between time spent in absolute and relative physical activity for people with COPD?
Phase 1 Participants will take part in semi-structured interview (30-45 minutes) about living with COPD and perceptions of physical activity and how they perceive intensity. This will also include photovoice and photo-elicitation. Demographic information will be recorded and participants will also complete several resp...
Phase 2:
Participants will take part in physical activity testing before and after pulmonary rehabilitation while wearing physical activity monitors. Demographic information will be recorded and participants will also complete several respiratory symptom and physical activity questionnaires. Participants will also wear the phys...
Sub-study:
Participants will be asked to take images of barriers during physical activity, facilitators during physical activity, feelings during physical activity and types of physical activity they take part in for 8 days after their final pulmonary rehabilitation class. Participants will then take part in a semi-structured int...
<|newrecord|> nctId: NCT06330610 id: 2021/0378/HP briefTitle: Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care Unit acronym: ENNUT-CI overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-06-01 date: 2027-08-01 date...
<|newrecord|> nctId: NCT06330597 id: 21-5196 briefTitle: NIVIA-Hemodynamics overallStatus: RECRUITING date: 2021-07-17 date: 2024-08-31 date: 2024-12-31 date: 2024-03-26 date: 2024-03-26 name: University Health Network, Toronto class: OTHER briefSummary: This is an investigator-initiated, single-center, single-arm pros...
<|newrecord|> nctId: NCT06330584 id: AIM Care Study briefTitle: Administration of Intranasal Midazolam for Anxiety in Palliative Care acronym: AIM Care overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2024-10-31 date: 2024-10-31 date: 2024-03-26 date: 2024-03-26 name: Insel Gruppe AG, University Hospital Bern c...
To safeguard blinding, placebo formulation will be produced with the same pH as the active study drug formulations to mimic nasal irritation induced by verum sprays. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Placebo Nasal Spray 0...
<|newrecord|> nctId: NCT06330571 id: Aligners in distalization briefTitle: The Efficiency of Clear Aligners in Maxillary Molar Distalization: A Randomized Clinical Trial. acronym: Aligner overallStatus: RECRUITING date: 2024-04-27 date: 2025-01-15 date: 2025-07-15 date: 2024-03-26 date: 2024-03-26 name: Ain Shams Unive...
<|newrecord|> nctId: NCT06330558 id: pheos briefTitle: Side-specific Factors for Conversion in Adrenalectomy for Pheochromocytoma. overallStatus: COMPLETED date: 2016-09-01 date: 2023-09-01 date: 2023-09-01 date: 2024-03-26 date: 2024-03-28 name: Zagazig University class: OTHER_GOV briefSummary: Context: Adrenalectomy ...
Methods: A retrospective analysis was conducted to include a total of 271 patients diagnosed with PHEO. These patients were separated into two groups: LRA (N=121) and LLA (N=150). The study period spanned from September 2016 to September 2023. conditions: Adrenal Tumor studyType: OBSERVATIONAL observationalModel: COHOR...
<|newrecord|> nctId: NCT06330545 id: STUDY02002161 briefTitle: Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2029-04 date: 2032-04 date: 2024-03-26 date: 2024-03-26 name: Dartmouth-Hitchcock Medical Center class: OTHER briefSummary: Th...
• Does targeted radiation therapy decrease recurrence of Dupuytren's contracture after treatment with Collagenase Clostridium Histolyticum?
Participants will undergo:
* Release of Dupuytren's Contracture after Collagenase Clostridium Histolyticum injection
* Daily radiation therapy treatment for 5 days followed by 6-8 week rest period and then another course of 5 days of radiation therapy conditions: Dupuytren Contracture studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: This is a prospective phase II trial ...
<|newrecord|> nctId: NCT06330532 id: 4-2023-1526 briefTitle: Impact of Preoperative Frailty and Cognitive Impairment on Postoperative Outcomes in Elderly Cardiac Surgery Patients overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-01 date: 2025-02-28 date: 2025-02-28 date: 2024-03-26 date: 2024-03-26 name: Yonsei Univer...
<|newrecord|> nctId: NCT06330519 id: Ainshams University Dentistry briefTitle: Impact of Different Techniques on The Efficacy of Anaesthesia in Mandibular Molars With Acute Irreversible Pulpitis overallStatus: COMPLETED date: 2023-09-25 date: 2024-02-21 date: 2024-02-21 date: 2024-03-26 date: 2024-03-26 name: Ain Shams...
* Preoperative intraligamentary corticosteroids injection
* Cryotherapy which is cold application on :
* Hard tooth structure ( crown of the tooth )
* Soft tissue overlying roots on the efficacy of the inferior alveolar nerve block anaesthesia in patients with mandibular molars with symptomatic irreversible pulpitis. The main question it aims to answer are: • Does intraligamentary dexamethazone injection increase the success rate of inferior alveolar nerve block wi...
Participants will describe their preoperative pain level to the investigator and describe their pain level during the treatment.
Researchers will compare cryotherapy to see if it increases the success rate of inferior alveolar nerve block. conditions: Pulpitis - Irreversible studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR coun...
<|newrecord|> nctId: NCT06330506 id: 123456123456 briefTitle: The Effect of Pressure Ulcer Care Package on the Risk of Pressure Ulcer Development overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2024-08-10 date: 2024-09-10 date: 2024-03-26 date: 2024-03-26 name: Cukurova University class: OTHER briefSummary: Th...
<|newrecord|> nctId: NCT06330493 id: AcoArt BTK Global Trial briefTitle: AcoArt Litos PCB Below-the-knee Global Trial overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-10 date: 2030-12 date: 2024-03-26 date: 2024-04-29 name: Acotec Scientific Co., Ltd class: INDUSTRY briefSummary: The objective of this study i...
<|newrecord|> nctId: NCT06330480 id: Check@Home briefTitle: Check@Home: General Population Screening for Early Detection of Atrial Fibrillation and Chronic Kidney Disease overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2027-11-01 date: 2028-11-01 date: 2024-03-26 date: 2024-03-26 name: Prof. Dr. Folkert W. Asselb...
This will be a population-based screening with a phased implementation and an iterative design in four regions in the Netherlands (Breda, Utrecht, Arnhem, Eindhoven). In total, a random sample of 160,000 people (aged 50-75 years) will be invited to participate in the study and another random sample of 160,000 people wi...
The overall screening program will consist of three phases: a home-based testing phase, diagnostic screening phase, and a treatment phase:
* Phase 1: Subjects will be invited for a home-based screening that includes home-based testing; urine collection for detection of elevated albuminuria, and a heart rhythm measurement using a smartphone app for detection of atrial fibrillation.
* Phase 2: Depending on the results on these home-based tests, subjects will be invited for further screening in a diagnostic screening facility. During this visit, physical data will be collected (height, weight, waist circumference, blood pressure, heart rhythm), blood will be drawn, and urine will be collected for t...
* Phase 3: Based on the results of the diagnostic screening, participants may be referred to their general practitioner for appropriate treatment (lifestyle advice/medication) according to the prevailing guidelines.
The primary study outcomes are:
Overall effectiveness of population based screening on atrial fibrillation and chronic kidney disease in subjects aged 50-75 years, based on:
* Participation rate of different screening strategies and phases;
* Yield of the screening (number of subjects with (newly) diagnosed disease and risk factors);
* Effectiveness of the atrial fibrillation screening, compared with standard care, based on the incidence of ischemic stroke);
* Effectiveness of the albuminuria screening, compared with standard care, based on the incidence of kidney failure events and Major Adverse Cardiovascular Events (MACE). conditions: Atrial Fibrillation conditions: Chronic Kidney Diseases conditions: Diabetes Mellitus, Type 2 studyType: INTERVENTIONAL phases: NA alloca...
<|newrecord|> nctId: NCT06330467 id: 2023-A02442-43 id: RIPH 2023-02 type: REGISTRY domain: sponsor's internal reference briefTitle: Prevalence of Dissociative Identity Disorder in At-risk Outpatient Groups Reporting Childhood Trauma. acronym: IDENTITY overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-03-31...
The investigators will also study the prevalence of other dissociative disorders and the frequency of complex post-traumatic stress disorder.
The investigators will also look for correlations between the type of maltreatment in childhood, the age of onset of trauma and the type of diagnosis of dissociative disorders.
The investigators hope to include 150 borderline patients, 150 FDC patients and 50 early psychosis patients.
Data collection will be done via a psychometric administration of 7 self-completion questionnaires as well as the completion of the SCID-D semi-structured interview. conditions: Dissociative Disorder studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription...
<|newrecord|> nctId: NCT06330454 id: 483/2020/Disp/AOUFe briefTitle: Painful Total Knee Replacement (TKA) and I-one Therapy overallStatus: RECRUITING date: 2020-10-22 date: 2025-10-21 date: 2025-10-21 date: 2024-03-26 date: 2024-03-28 name: University Hospital of Ferrara class: OTHER briefSummary: Arthroplasty operatio...
<|newrecord|> nctId: NCT06330441 id: MOU-2021-01 briefTitle: Pancreatic Cancer Screening in a Population at High Risk acronym: ScrePan overallStatus: RECRUITING date: 2022-01-07 date: 2025-01-06 date: 2028-01-06 date: 2024-03-26 date: 2024-04-01 name: Masaryk Memorial Cancer Institute class: OTHER name: Masaryk Univers...
<|newrecord|> nctId: NCT06330428 id: MU-Ebe-ZDKY-02 briefTitle: Investigation of the Effect of Sexuality-Based Family Planning Education Given to Women Via Podcast on Contraceptive Method Selection and Sexual Life Quality overallStatus: RECRUITING date: 2024-02-09 date: 2024-06-10 date: 2024-08-10 date: 2024-03-26 date...
Accordingly, the hypotheses of the study are as follows:
Hypotheses of the Project H1: Sexuality-based family planning education via podcast has an effect on women's conscious and appropriate contraceptive method selection.
H2: Sexuality-based family planning education via podcast has a positive effect on women's sexual life quality.
H3: Sexuality-based family planning education via podcast has a positive effect on the quality of sexual life of women by increasing their level of contraceptive knowledge.
H4: Sexuality-based family planning education via podcast has a positive effect on women's attitudes towards family planning. conditions: Contraception studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: One control group, one experimental group primaryP...
<|newrecord|> nctId: NCT06330415 id: 25603 briefTitle: Effect and Process Evaluation of the SME Tool overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-08-01 date: 2024-03-26 date: 2024-03-26 name: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) class: OTHER name: ZonMw: Th...
<|newrecord|> nctId: NCT06330402 id: N-20220063 briefTitle: Exploration of Gait Biomechanics and Pain overallStatus: RECRUITING date: 2023-09-26 date: 2026-12-31 date: 2026-12-31 date: 2024-03-26 date: 2024-03-26 name: Kristian Kjær Petersen class: OTHER briefSummary: This interventional study aims to test gait biomech...
* How do gait patterns change during painful walking?
* Can pain sensitivity testing and gait biomechanics predict experimental knee pain intensity?
Participants will receive two knee injections: a) Hypertonic saline (painful condition) and b) Isotonic saline (control condition). conditions: Pain conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: PARTI...
<|newrecord|> nctId: NCT06330389 id: MRC-01-20-1074 briefTitle: Burn Injuries During COVID-19 Pandemic and Its Influence on Length of Stay overallStatus: COMPLETED date: 2020-04-01 date: 2021-03-01 date: 2021-06-25 date: 2024-03-26 date: 2024-03-26 name: Hamad Medical Corporation class: INDUSTRY briefSummary: Burn inju...
<|newrecord|> nctId: NCT06330376 id: PT-2022-30735 briefTitle: Diaphragmatic Breathing Exercises for Post-COVID-19 Diaphragmatic Dysfunction (DD) overallStatus: RECRUITING date: 2024-03-01 date: 2024-06-01 date: 2024-09-01 date: 2024-03-26 date: 2024-04-05 name: University of Minnesota class: OTHER briefSummary: Diaphr...
The purpose of this study is to address Diaphragmatic Dysfunctional (DD) breathing seen in patients with Post-Acute Sequelae of COVID-19 (PASC), which results in shortness of breath/chest tightness and subsequent fatigue. Targeting shortness of breath and subsequent fatigue as a central symptom of PASC will alleviate l...
<|newrecord|> nctId: NCT06330363 id: METC 23-049 briefTitle: The Impact of Low Level Laser Treatment on Skeletal Muscle and Skin Tissue acronym: LASER overallStatus: RECRUITING date: 2024-04-01 date: 2024-08-31 date: 2024-12-31 date: 2024-03-26 date: 2024-04-17 name: Maastricht University Medical Center class: OTHER br...
Objective: To assess the impact of acute laser treatment on muscle tissue mitochondrial respiration in vivo in healthy, young adults. Secondary objectives include the in vivo assessment of cellular energy, anabolic, angiogenic and inflammatory pathways, along with enzyme activity within muscle and skin.
Study design: Within-subject study.
Study population: 12 healthy (BMI 18.5-30 kg/m2) young (age: 18-35 y) adults (6 men and 6 women).
Intervention: One leg of the subjects will receive LLLT, while the other leg will receive no treatment. After the treatment muscle and skin biopsy samples will be taken from both legs.
Main study parameters/endpoints: The primary outcome will be mitochondrial respiration of the LLLT treated and non-treated leg based on muscle samples. Secondary study parameters are muscle and skin gene expression, protein signalling and enzyme activity. conditions: Muscles Metabolism conditions: Skin Metabolism study...
<|newrecord|> nctId: NCT06330350 id: METC 2023-0193 briefTitle: Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling overallStatus: RECRUITING date: 2024-01-01 date: 2025-08-31 date: 2025-12-31 date: 2024-03-26 date: 2024-03-26 name: Maastricht University Medical Ce...
<|newrecord|> nctId: NCT06330337 id: ZSLL-KY-2024-010-01 briefTitle: Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma overallStatus: RECRUITING date: 2024-04-01 date: 2026-12-31 date: 2027-12-31 date: 2024-03-26 date: 2024-03-26 name: The Third Aff...
<|newrecord|> nctId: NCT06330324 id: METC 2023-0182 briefTitle: Reproductive Options in Inherited Skin Diseases acronym: REPRO-ISD overallStatus: ENROLLING_BY_INVITATION date: 2024-01-01 date: 2026-09-01 date: 2026-09-01 date: 2024-03-26 date: 2024-03-26 name: Maastricht University Medical Center class: OTHER briefSumm...
To achieve this, the investigators aim to retrospectively collect data from a cohort of patiens/couples affected by an inherited skin disease on a national level (in the Netherlands) and also an international level from various countries in Europe. conditions: Ichthyosis conditions: Palmoplantar Keratoses conditions: E...
<|newrecord|> nctId: NCT06330311 id: 20/551-EC briefTitle: Effectiveness of Whole-Body Vibration acronym: WBVibration overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-29 date: 2024-09-29 date: 2024-09-29 date: 2024-03-26 date: 2024-04-12 name: Universidad Complutense de Madrid class: OTHER name: Hospital Infantil Uni...
Within interventions aiming to manage CP Whole-Body Vibration (WBV) has shown some benefits such as reducing spasticity or improving strength and functionality of the lower limbs.
The aim of this study is to assess the effectiveness on motor function and spasticity of the lower limbs by adding an intervention with WBV to an evidence-based multimodal physiotherapy treatment in children with CP. conditions: Spastic Cerebral Palsy conditions: Physical Therapy Modalities conditions: Vibration; Expos...
<|newrecord|> nctId: NCT06330298 id: 202000479 briefTitle: Improving Social Cognition and Social Behaviour in Various Brain Disorders acronym: T-ScEmo4ALL overallStatus: RECRUITING date: 2021-05-31 date: 2025-01-31 date: 2025-01-31 date: 2024-03-26 date: 2024-04-16 name: University Medical Center Groningen class: OTHER...
Recently, a first multi-faceted treatment for social cognitive impairments in TBI was developed and evaluated; T-ScEmo (Training Social Cognition and Emotion). T-ScEmo turned out to be effective in reducing social cognitive symptoms and improving daily life social functioning in this particular group, with effects last...
Unfortunately, up till now there are no evidence based, transdiagnostic treatment possibilities available for these impeding social cognition impairments in neurological patient groups, other than TBI. Therefore the aim of the present study is to investigate whether T-ScEmo is effective for social cognition disorders i...
It is expected that T-ScEmo will be effective for various neurological disorders, based on previous research of Westerhof-Evers et al. (2017, 2019). Since social cognition disorders within patients with traumatic brain injury do all have the same ethiology it is expected that the treatment will show the same effects fo...
Waiting list condition T0, baseline measurement at point of inclusion (at least \> 6 months post-acute injuries) T1, post measurement within 3 months after T0 T2, follow-up measurement within 3 - 5 months after T1
TBI group T1, post measurement within 2 weeks after treatment T2, follow-up measurement within 3 - 5 months after treatment
The participating patients are randomly allocated into two groups: an experimental condition and a waiting list condition.
In addition, a group of patients with Traumatic Brain Injury will receive T-ScEmo following regular care. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The neuropsychologist who leads T1 and T2 measurements will be masked for the fact of which patient will be draw in which clinical condition (experiment...
<|newrecord|> nctId: NCT06330285 id: e learning pgme/cpet briefTitle: Comparison of E-Learning and Face-to-Face Learning in Cardiopulmonary Exercise Test Training overallStatus: NOT_YET_RECRUITING date: 2024-03-22 date: 2024-06-15 date: 2024-08-15 date: 2024-03-26 date: 2024-03-26 name: Kayseri City Hospital class: OTH...
<|newrecord|> nctId: NCT06330272 id: UCeuma briefTitle: Accuracy of Spectrophotometry in Hypomineralized Lesions Treated With CPP-ACPF Dental Mousse: Clinical Study acronym: ASHLTDMCS overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-01 date: 2025-03 date: 2024-03-26 date: 2024-03-28 name: Meire Coelho Ferreir...
The application of Tooth Mousse Plus to the MIH lesion will be carried out under relative isolation and with the aid of a microbrush. The cream will remain on the surface for 1 minute. The application will be carried out once a week, for four consecutive weeks. primaryPurpose: TREATMENT masking: NONE count: 98 type: ES...
<|newrecord|> nctId: NCT06330259 id: new AMH assay briefTitle: Does the AMH Concentration Depend on the Menstrual Cycle? acronym: AMH overallStatus: COMPLETED date: 2017-07-01 date: 2018-06-30 date: 2019-12-31 date: 2024-03-26 date: 2024-04-01 name: University of Basel class: OTHER name: Roche Diagnostics briefSummary:...
<|newrecord|> nctId: NCT06330246 id: IRB300005280 id: R01DK137784 type: NIH link: https://reporter.nih.gov/quickSearch/R01DK137784 briefTitle: O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease overallStatus: RECRUITING date: 2024-05-01 date: 2030-12-31 date: 2031-12-31 date: 2024-03-26 date: 2024-04-03...
The study will recruit adult participants with a history of calcium oxalate kidney stones who are not colonized with Oxalobacter formigenes.
Participants will
* ingest fixed diets containing low and moderately high amounts of oxalate for 4 days at a time
* collect urine, blood and stool samples during the fixed diets
* ingest a preparation of live Oxalobacter formigenes to induce colonization with Oxalobacter formigenes conditions: Kidney Stone conditions: Kidney Calculi conditions: Urolithiasis conditions: Urolithiasis, Calcium Oxalate conditions: Nephrolithiasis conditions: Nephrolithiasis, Calcium Oxalate conditions: Oxalate Uro...
<|newrecord|> nctId: NCT06330233 id: YJiang briefTitle: Different Amounts of Moxibustion in the Treatment of DPN: A Clinical RCT Study overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-04-07 date: 2026-12-31 date: 2024-03-26 date: 2024-03-26 name: Zhejiang Chinese Medical University class: OTHER_GOV name: T...
<|newrecord|> nctId: NCT06330220 id: 2010-015-1161 briefTitle: Visual Function Change in Wet Age-related Macular Degeneration Patients With Better Baseline Visual Acuity overallStatus: COMPLETED date: 2021-02-10 date: 2022-02-28 date: 2022-02-28 date: 2024-03-26 date: 2024-03-26 name: Seoul National University Hospital...
<|newrecord|> nctId: NCT06330207 id: IRB202301471 id: K99DE031723 type: NIH link: https://reporter.nih.gov/quickSearch/K99DE031723 briefTitle: An Emergency Department (ED) Provider Centered Intervention for Non-Traumatic Dental Condition Management (NTDC) overallStatus: NOT_YET_RECRUITING date: 2025-08-01 date: 2027-02...
<|newrecord|> nctId: NCT06330194 id: AID-study briefTitle: Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease overallStatus: RECRUITING date: 2024-04-18 date: 2024-12-31 date: 2024-12-31 date: 2024-03-26 date: 2024-04-22 name: Steno Diabetes Center Copenhagen class: OTHE...
The main objective is:
• To test if the AID is superior in regulating blood sugar levels compared with usual care in patients with advanced renal disease
Secondary objectives are: