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* To assess the effectiveness of CGM compared with conventional monitoring in reducing the comprehensive complication index (CCI) for patients with diabetes or impaired glucose tolerance (IGT) within 30 days after surgery. |
* To analyze the impact of different age groups, types of surgery, preoperative levels of HbA1c, and preoperative 24h glycemic variations on the improvement of surgical outcomes under the CGM model. |
Participants will receive CGM prescribed by the attending physician for at least 6 hours before surgery. Glucose monitoring should be continued until the 7th day after surgery or discharge. |
The investigators will compare conventional monitoring group to see if CGM could reduce the CCIs for patients with diabetes or impaired glucose tolerance within 30 days after surgery. conditions: Comprehensive Complication Index studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL pri... |
<|newrecord|> nctId: NCT06331910 id: TITNCUES briefTitle: Efficacy and Safety of Topical Insulin for Neurotrophic Corneal Ulcers overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-05-01 date: 2024-03-26 date: 2024-03-26 name: Assiut University class: OTHER briefSummary: To evaluate Safety an... |
<|newrecord|> nctId: NCT06331897 id: Bronchial asthma briefTitle: Bronchial Asthma & Its Exacerbation overallStatus: NOT_YET_RECRUITING date: 2025-01-01 date: 2026-01-01 date: 2026-06-01 date: 2024-03-26 date: 2024-03-26 name: Assiut University class: OTHER briefSummary: Our goals is to assess : |
1¬_ the role of spirometer in case of asthma exacerbation 2_hematological parameters (N/L ratio \& platelet indices \&CRP )in asthma exacerbation for diagnosing and classifying asthma severity and its exacerbation conditions: Bronchial Asthma studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: P... |
<|newrecord|> nctId: NCT06331884 id: PCZ_Phase1 briefTitle: Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics/-Dynamics of AK1967 (Procizumab) overallStatus: RECRUITING date: 2024-03-07 date: 2024-07-31 date: 2024-07-31 date: 2024-03-26 date: 2024-03-26 name: 4TEEN4 Pharmaceuticals GmbH class: INDUSTR... |
Recently, a cDPP3-antagonizing antibody called AK1967 (commonly referred to as Procizumab) has been developed. In animal models of cardiogenic- and septic shock, inhibition of cDPP3 by AK1967 resulted in improved cardiac function and survival. Furthermore, AK1967 has shown an excellent safety record in different precli... |
<|newrecord|> nctId: NCT06331871 id: 2004202111621 briefTitle: Effectiveness of US-PENS for Patients With Post-surgical Shoulder Pain overallStatus: RECRUITING date: 2024-02-01 date: 2025-10-30 date: 2025-10-30 date: 2024-03-26 date: 2024-03-26 name: Universidad Rey Juan Carlos class: OTHER briefSummary: The aim of thi... |
This is a randomized, longitudinal, prospective and quasi-experimental clinical trial in which a total of 70 patients divided into two groups; physiotherapy protocol group (n=35) and experimental group to which the same protocol was practiced and a US-PENS session was added (n=35). |
The intervention and follow-up period of the participants took place over 12 weeks. conditions: Ultrasound-Guided Percutaneous Electrical Nerve Stimulation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 70 patients with shoulder pain undergoing arth... |
<|newrecord|> nctId: NCT06331858 id: KutahyaHSU-DRGOKPINARDROMER-43 briefTitle: The Effect of Adding Instrumented Hip Concentric Abductor Strengthening Exercise in Knee Osteoarthritis overallStatus: RECRUITING date: 2023-09-20 date: 2024-03-29 date: 2024-03-29 date: 2024-03-26 date: 2024-03-26 name: Kutahya Health Scie... |
2. CONTROL GROUP primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Before and after the treatment, all patients were evaluated by a blind evaluator in terms of physical examination, pain and functionality, physical performance, quality of life and gait parameters. whoMasked: INVESTIGATOR whoMasked: OUTCOMES... |
<|newrecord|> nctId: NCT06331845 id: NPC012 briefTitle: Stop and go Strategy as First-line Treatment for Widely Metastatic Nasopharyngeal Carcinoma overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2028-05-01 date: 2024-03-26 date: 2024-03-26 name: Fujian Cancer Hospital class: OTHER_GOV briefSu... |
<|newrecord|> nctId: NCT06331832 id: 2323-EAP id: 2021-002339-44 type: EUDRACT_NUMBER briefTitle: Expanded Access of Imvotamab (IGM-2323) in Patients With R/R NHL overallStatus: NO_LONGER_AVAILABLE date: 2024-03-26 date: 2024-03-26 name: IGM Biosciences, Inc. class: INDUSTRY briefSummary: Expanded Access of Imvotamab (... |
<|newrecord|> nctId: NCT06331819 id: 7-3-2024 briefTitle: Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms. acronym: VasOSA overallStatus: RECRUITING date: 2024-03-10 date: 2025-01-01 date: 2025-03-01 date: 2024-03-26 date: 2024-03-26 name: Jordan Collaborating Cardiolog... |
* To prospectively obtain demographic and clinical information of patients referred for a sleep study. |
* To determine the diagnostic value of facial discoloration as potential marker for obstructive sleep apnea to increase detection rate for the condition. |
* To establish a correlation between obstructive sleep apnea and vasovagal symptoms with resulting increased smoking tendency and study the effect of treatment on the disorders. |
* To determine the association between timing of appearance of obstructive sleep apnea symptoms and initiation of smoking. conditions: Obstructive Sleep Apnea conditions: Vasovagal Syncope conditions: Smoking conditions: Acanthosis Nigricans studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTI... |
<|newrecord|> nctId: NCT06331806 id: IEO 398 briefTitle: Myocardial Fibrosis Identification in Patients With Anthracycline-induced Cardiotoxicity overallStatus: RECRUITING date: 2018-02-22 date: 2024-12-31 date: 2024-12-31 date: 2024-03-26 date: 2024-03-26 name: European Institute of Oncology class: OTHER briefSummary:... |
<|newrecord|> nctId: NCT06331793 id: IEO 1849 briefTitle: Pulsed Electromagnetic Fields for Analgesia Post Mastectomy acronym: Algocare overallStatus: RECRUITING date: 2023-05-09 date: 2024-12-31 date: 2024-12-31 date: 2024-03-26 date: 2024-03-26 name: European Institute of Oncology class: OTHER briefSummary: Study aim... |
<|newrecord|> nctId: NCT06331780 id: WS10370 id: 2023-A02153-42 type: OTHER domain: ANSM (France) briefTitle: Refractive Status and Accommodation Response Under Different Experimental Conditions. overallStatus: RECRUITING date: 2024-02-22 date: 2024-07-31 date: 2024-12-31 date: 2024-03-26 date: 2024-03-26 name: Essilor... |
<|newrecord|> nctId: NCT06331767 id: 2024P000654 briefTitle: Development of a Multilevel HIV Prevention Intervention for the Emergency Department acronym: mSYNC overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2029-04 date: 2029-04 date: 2024-03-26 date: 2024-03-26 name: Brigham and Women's Hospital class: OTHER b... |
<|newrecord|> nctId: NCT06331754 id: ATMANHEALTH001 briefTitle: Technology-Enabled Remote Hypertension Management To Advance Health Equity overallStatus: NOT_YET_RECRUITING date: 2024-03-18 date: 2025-09-17 date: 2026-03-17 date: 2024-03-26 date: 2024-03-26 name: Atman Health, Inc class: INDUSTRY briefSummary: The prim... |
<|newrecord|> nctId: NCT06331741 id: 0403 briefTitle: Collagen for Treatment of Musculoskeletal Injuries overallStatus: RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2026-03-01 date: 2024-03-26 date: 2024-03-26 name: I.M. Sechenov First Moscow State Medical University class: OTHER briefSummary: The purpose of the ... |
Evaluation of the clinical efficacy and safety of the use of collagen matrix/membrane in the surgical treatment of the consequences of injuries and diseases of the musculoskeletal system (anterior cruciate ligament tears, rigid first toe) by using IKDC, KOOS, ACLOAS, VAS, AOFAS, SF-36 scales conditions: Anterior Crucia... |
<|newrecord|> nctId: NCT06331728 id: IGNX-T1 briefTitle: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IGNX001 overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2025-08 date: 2025-10 date: 2024-03-26 date: 2024-03-26 name: IgGenix Australia Pty Ltd class: INDUSTRY briefSummary... |
<|newrecord|> nctId: NCT06331715 id: ML1005 briefTitle: Bioequivalence Study of Palbociclib 125 mg Capsules of Iclos vs. Ibrance (Palbociclib) Capsules 125 mg overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2024-08-01 date: 2024-08-31 date: 2024-03-26 date: 2024-03-26 name: Megalabs class: INDUSTRY briefSummar... |
<|newrecord|> nctId: NCT06331702 id: CDBJEIV2023001 briefTitle: Immunogenicity of Japanese Encephalitis Vaccine Co-administered With Measles-Mumps-Rubella Vaccine (MMR) overallStatus: RECRUITING date: 2024-03-02 date: 2024-09-30 date: 2024-12-31 date: 2024-03-26 date: 2024-03-26 name: Liaoning Chengda Biotechnology CO.... |
<|newrecord|> nctId: NCT06331689 id: HP-epidemıology briefTitle: EPIDEMIOLOGY AND ITS RESULTS IN HIP FRACTURES FOLLOWED IN POSTOPERATIVE INTENSIVE CARE acronym: Hip fractures overallStatus: COMPLETED date: 2021-02-01 date: 2021-04-01 date: 2021-07-01 date: 2024-03-26 date: 2024-03-26 name: Kutahya Health Sciences Unive... |
Participant population/health conditions:Patients over the age of 18 who are hospitalized in the intensive care unit of our hospital after hip fracture operation. conditions: Hip Fracture conditions: Mortality Rate studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 68 type: ACTUAL... |
<|newrecord|> nctId: NCT06331676 id: 69HCL23_1120 id: 2023-A02339-36 type: OTHER domain: ID RCB briefTitle: Developing a Complex ex Vivo Endometrial Tissue Model to Improve Endometriosis Care acronym: OTEndo overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-10 date: 2025-10 date: 2024-03-26 date: 2024-03-26 na... |
There is no cure for endometriosis. Hormonal treatments should be the first line therapy. The benefit-risk ratio of symptomatic treatment with hormone therapy varies greatly from one woman to another. The pathophysiology of endometriosis and the mechanisms of action of these treatments are still poorly understood. This... |
The aim of this project is to develop a complex ex vivo endometrial model recapitulating the organisation and properties of the human endometrium using innovative tissue bioengineering methods. This model will make it possible to develop a pre-clinical approach that predicts individual response to different types of ho... |
<|newrecord|> nctId: NCT06331663 id: KMUHIRB-F(II)-20240055 briefTitle: SPI and Remifentanil in Skull Pin Fixation overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-06-20 date: 2024-06-20 date: 2024-03-26 date: 2024-03-26 name: Kaohsiung Medical University Chung-Ho Memorial Hospital class: OTHER briefSummar... |
Data collection: heart rate, mean blood pressure, Surgical Pleth Index, bispectral Index, pulse pressure variance, systolic pressure variance, concentrations of propofol and remifentanil before 2 mins, during, 5, and 15 mins of skull pin fixation were recorded and analyzed. conditions: Pain, Procedural studyType: INTER... |
<|newrecord|> nctId: NCT06331650 id: CROC202314 briefTitle: A Single-arm Pilot Study of First-line Treatment With Carbognilumab Combined With Chemotherapy in Patients With STK11-mutated Advanced or Postoperative Recurrent Non-small Cell Lung Cancer overallStatus: RECRUITING date: 2023-08-09 date: 2025-08 date: 2025-10 ... |
<|newrecord|> nctId: NCT06331637 id: 3782 briefTitle: Outcomes of Transanal Tran-section and Single-stapled (TTSS) Ileal Pouch-Anal Anastomosis acronym: TTSS-Pouch overallStatus: NOT_YET_RECRUITING date: 2024-07-31 date: 2026-07-31 date: 2026-12-31 date: 2024-03-26 date: 2024-03-26 name: Istituto Clinico Humanitas clas... |
<|newrecord|> nctId: NCT06331624 id: GRI-0621-IPF-02 briefTitle: Biomarker Modulation and the Inhibition of NKT1 Cells by Oral GRI-0621 in Patients With IPF overallStatus: RECRUITING date: 2024-03 date: 2025-01 date: 2025-01 date: 2024-03-26 date: 2024-03-26 name: GRI Bio Operations, Inc. class: INDUSTRY briefSummary: ... |
<|newrecord|> nctId: NCT06331611 id: Motor briefTitle: MONITORING NEUROMUSCULAR BLOCK IN PAEDIATRIC ANAESTHESIA acronym: MOTOR overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-31 date: 2025-12-31 date: 2024-03-26 date: 2024-03-27 name: Istituto Giannina Gaslini class: OTHER briefSummary: To date there i... |
The main objective of the study is to analyse the incidence of sugammadex use and the total dose/kg, with and without the aid of quantitative neuromuscular monitoring. |
Secondary objectives are: |
* the time required to extubate different patients, |
* the incidence of respiratory complications at extubation, |
* the need to administer additional doses of sugammadex. A prospective RCT. Patients will be divided into two study groups; in the first group, quantitative neuromuscular monitoring based on electromyography (EMG) will be used, while in the second group, the same monitoring will be applied but covered (blinded to the a... |
* Children between 2 months and 6 years |
* Children who will undergo elective non cardiac surgery (maximum two hours of anesthesia time with tracheal intubation receiving a non depolarizing blockade agent), |
* Acquisition of informed consent by a legally recognized representative capable of understanding the document and providing consent on behalf of the participant. |
* Children under 2 months of age or over 12 years of age, |
* Children with an ASA classification \> 3, |
* Presence of neuromuscular disease, channelopathy, or any clinical condition that contraindicates the administration of neuromuscular muscle relaxants, |
* Confirmed or suspected allergy to sugammadex or rocuroniumt, |
* Presence of amputation or limb malformations that make placement of neuromuscular monitoring impossible, |
* Any specific contraindication to any aspect of the protocol. 12 months The randomization process will performed using numbers randomized by a computer-generated random number sequence. The randomization list will be prepared by independent statistician . The subjects will be assigned to the treatment arm in a seque... |
One hundred children undergo in the clinically guided group and 100 children in the neuromuscular monitoring groups with the aim to include 200 children in total. |
Demographics and baseline characteristics with mean, median, standard deviation, and range (minimum, maximum) will generated for each arm. Subject disposition, including the number of subjects withdrawn or discontinued from the study, for each arm will summarized. The study will follow the CONSORT guidelines for statis... |
<|newrecord|> nctId: NCT06331598 id: ML43332 id: 2022-003708-33 type: EUDRACT_NUMBER briefTitle: A Study of Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors With Resectable Disease With Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI... |
<|newrecord|> nctId: NCT06331585 id: KY-2024004 briefTitle: Effect of Low-dose Radiotherapy on Tumor Immune Microenvironment in Oligometastases of NSCLC After Immunotherapy overallStatus: WITHDRAWN date: 2024-03-18 date: 2025-03-18 date: 2026-03-18 date: 2024-03-26 date: 2024-04-25 name: Hetian District People's Hospit... |
<|newrecord|> nctId: NCT06331572 id: 1stChongqingMU-TRD briefTitle: Exploring Blood Plasma Metabolomics: Unraveling the Metabolic Landscape in Treatment-Resistant Adolescent Depression overallStatus: COMPLETED date: 2021-08-01 date: 2021-10-25 date: 2023-12-20 date: 2024-03-26 date: 2024-03-26 name: First Affiliated Ho... |
<|newrecord|> nctId: NCT06331559 id: SIM0501-101 briefTitle: Study of SIM0501 Alone and in Combination in Patients With Advanced Solid Tumors overallStatus: RECRUITING date: 2024-03-19 date: 2026-06-30 date: 2027-12-31 date: 2024-03-26 date: 2024-04-02 name: Jiangsu Simcere Pharmaceutical Co., Ltd. class: INDUSTRY name... |
<|newrecord|> nctId: NCT06331546 id: IRB300004693 id: R01DK137784 type: NIH link: https://reporter.nih.gov/quickSearch/R01DK137784 briefTitle: Gut Oxalate Absorption in Calcium Oxalate Stone Disease overallStatus: RECRUITING date: 2024-05-01 date: 2030-12-31 date: 2031-12-31 date: 2024-03-26 date: 2024-04-03 name: Univ... |
The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones. |
Participants will |
* ingest fixed diets containing low and moderately high amounts of oxalate for 5 days at a time |
* ingest a soluble form of oxalate and sugar preparations to test gut permeability |
* collect urine, blood, stool and breath sample during the fixed diets and the soluble oxalate test conditions: Kidney Stone conditions: Kidney Calculi conditions: Urolithiasis conditions: Urolithiasis, Calcium Oxalate conditions: Nephrolithiasis conditions: Nephrolithiasis, Calcium Oxalate conditions: Oxalate Urolithi... |
<|newrecord|> nctId: NCT06331533 id: IstanbulTRH1 briefTitle: Intradermal BoNT-A Treatment in Erythematotelangiectatic Rosacea overallStatus: COMPLETED date: 2022-11-01 date: 2023-05-01 date: 2023-06-01 date: 2024-03-26 date: 2024-03-29 name: Istanbul Training and Research Hospital class: OTHER_GOV briefSummary: Invest... |
<|newrecord|> nctId: NCT06331520 id: Desineo briefTitle: NEPA Combined With Olanzapine, Dexamethasone-sparing for the Effect of CINV in Patients Receiving HEC Regimens overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2026-05-01 date: 2024-03-26 date: 2024-03-26 name: Fudan University class: OTH... |
<|newrecord|> nctId: NCT06331507 id: HUM00176904 briefTitle: Refinement and Assessment of New MRI Technologies for Cardiovascular Exams Using the Phillips CMR Patch overallStatus: TERMINATED date: 2021-09-02 date: 2023-06-29 date: 2023-06-29 date: 2024-03-26 date: 2024-03-26 name: University of Michigan class: OTHER na... |
<|newrecord|> nctId: NCT06331494 id: SICAS briefTitle: Efficacy of Butylphthalide on Symptomatic Atherosclerotic Stenosis in Middle Cerebral Artery acronym: SICAS overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2026-05-31 date: 2026-08-31 date: 2024-03-26 date: 2024-03-26 name: First Affiliated Hospital, Sun Y... |
<|newrecord|> nctId: NCT06331481 id: 0005-22-HYMC briefTitle: The Effect of Over Weight on Oocytes Quality in IVF Patients acronym: IVF overallStatus: ACTIVE_NOT_RECRUITING date: 2022-02-01 date: 2023-12-31 date: 2024-07 date: 2024-03-26 date: 2024-03-26 name: Hillel Yaffe Medical Center class: OTHER_GOV briefSummary: ... |
This study is prospective observational cohort study performed between February 2022 until June 2022 in a single university-affiliated hospital. conditions: IVF conditions: Overweight studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50 type: ACTUAL name: Fullicular fluid for cytol... |
<|newrecord|> nctId: NCT06331468 id: MCC-23-GYN-10 briefTitle: Hypofractionated Radiochemotherapy overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-08-01 date: 2028-08-01 date: 2024-03-26 date: 2024-03-26 name: Denise Fabian class: OTHER briefSummary: The goal of this clinical trial is to investigate the us... |
* What is the MRI-assessed rate of response at 1-month and 3-months post-treatment? |
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