text stringlengths 0 197k |
|---|
<|newrecord|> nctId: NCT06308965 id: Z-2023088 briefTitle: Does Vessel-sparing Surgery in Anterior Approach Total Hip Arthroplasty Change Clinical Outcome? acronym: USP overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2027-03 date: 2024-03-13 date: 2024-03-13 name: Ziekenhuis Oost-Limburg class: OTHE... |
The surgical technique of the vessel-sparing procedure will be described and investigated in a prospective blinded RCT. The investigators hypothesize that the vessel-sparing technique is feasible in 60% of the patients. If these vessels were not sacrificed, the investigators expect the incidence of TFL tendinopathy to ... |
Weighted randomization (1:2) is applied to compensate for a dropout of patients planned for vessel sparing surgery, but in whom the vessels were damaged unintendedly. In case a bilateral procedure will be performed, each side is randomized individually. |
Surgery will be performed by the surgeon. Data collection before and after surgery is collected by personal assistant who is unaware of group assignment. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 300 type: ESTIMATED name: Vessel technique measure: a) Incidence of TFL tendinopathy me... |
<|newrecord|> nctId: NCT06308952 id: 2024SL0006 briefTitle: Effectiveness of Atorvastatin in Preventing Cerebrovascular Events After Flow Diverter Implantation overallStatus: NOT_YET_RECRUITING date: 2024-03-05 date: 2027-03-31 date: 2027-07-31 date: 2024-03-13 date: 2024-03-13 name: Zhujiang Hospital class: OTHER brie... |
At present, FD has been used in more than 250,000 cases worldwide, and the overall 1-year complete occlusion rate of aneurysms can reach 75%-85.5%. However, although the current imaging prognosis of FD is encouraging, the perioperative complications of FD are as high as 12.9%, including ischemic complications, SAH, and... |
Atorvastatin is widely used in the primary and secondary prevention of cardiovascular and cerebrovascular diseases. Its main effect is to improve the incidence of cardiovascular and cerebrovascular events by reducing blood lipids. Although the mechanism of clinical benefit of lipid-lowering by atorvastatin is not compl... |
However, there is no high-quality clinical evidence for the use of atorvastatin in intracranial aneurysm stent implantation. Previous retrospective studies have shown that atorvastatin is the only protective factor for in-stent restenosis after flow diverter implantation in intracranial aneurysms. In a retrospective ob... |
Therefore, this study planned to conduct a randomized controlled clinical trial to confirm the efficacy and safety of oral atorvastatin in the prevention of cerebrovascular adverse events after stent implantation in patients with unruptured intracranial aneurysms, and to provide objective evidence for the treatment dec... |
<|newrecord|> nctId: NCT06308939 id: IRB-2024-198 briefTitle: Eribulin Combined With Sintilimab as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Breast Cancer:A Multicenter, Single-arm,Phase II Clinical Trial overallStatus: NOT_YET_RECRUITING date: 2024-03-08 date: 2025-12-31 date: ... |
<|newrecord|> nctId: NCT06308926 id: MRG23ARDS briefTitle: MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients acronym: SUMMIT overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-02-01 date: 2026-07-01 date: 2024-03-13 date: 2024-03-13 name: MedRegen LLC class: INDUSTRY name: Vanderbilt ... |
The aim is to determine the safety and preliminary efficacy of MRG-001 across two dose ranges. conditions: Acute Respiratory Distress Syndrome conditions: Respiratory Failure conditions: Respiratory Distress Syndrome conditions: Respiratory Tract Diseases conditions: Cytokine Storm studyType: INTERVENTIONAL phases: PHA... |
<|newrecord|> nctId: NCT06308913 id: 2023-1722 id: UW23121 type: OTHER domain: UWCCC id: A534260 type: OTHER domain: UW Madison id: Protocol Version 2/15/2024 type: OTHER domain: UW Madison id: P50DE026787 type: NIH link: https://reporter.nih.gov/quickSearch/P50DE026787 id: P50CA278595-07 type: NIH link: https://report... |
<|newrecord|> nctId: NCT06308900 id: CL_SIMULATION_01 briefTitle: Non-technical Skills of Clinical Simulation in Physiotherapy Students overallStatus: RECRUITING date: 2024-02-26 date: 2024-03-31 date: 2024-04-30 date: 2024-03-13 date: 2024-03-15 name: University of Valencia class: OTHER briefSummary: Clinical simulati... |
However, if we focus on physiotherapy, the use of clinical simulation is a very new field and therefore requires great research. The investigators still do not have the consistency or experience as in other health branches such as medicine or nursing, in which they have been using simulators for years for the learning ... |
For all this, and for the situation of need generated in recent years, in which internships in hospitals and clinical centers were completely abolished, the need for our research is justified, which will allow the acquisition of non-technical skills among novice students. in physiotherapy, without the need for contact ... |
<|newrecord|> nctId: NCT06308887 id: 01 briefTitle: Comparison of Ultrasound-Guided Perimeniscal Steroid and 5% Dextrose Injections in Knee Osteoarthritis overallStatus: COMPLETED date: 2023-10-02 date: 2024-02-02 date: 2024-03-02 date: 2024-03-13 date: 2024-03-13 name: Kastamonu University class: OTHER briefSummary: I... |
Method: Patients with medial knee pain and meniscal extrusion were randomly divided into two groups using the double-block randomization method. Group 1 included 15 patients who were administered an ultrasound-guided perimeniscal steroid injection, while Group 2 included 16 patients who were administered an ultrasound-... |
<|newrecord|> nctId: NCT06308874 id: JH-222-101 briefTitle: Phase 1 Study to Investigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females overallStatus: COMPLETED date: 2023-01-02 date: 2023-02-17 date: 2023-02-17 date: 2024-03-13 date: 2024-03-13 name: J2H Biotech class: INDUSTRY briefSummary: - Objectives: ... |
<|newrecord|> nctId: NCT06308861 id: JH-201-101 briefTitle: Phase 1 Study to Investigate Safety, Tolerability, PK/PK of J2H-1702 in Healthy Males overallStatus: COMPLETED date: 2020-08-12 date: 2021-06-25 date: 2021-07-13 date: 2024-03-13 date: 2024-03-13 name: J2H Biotech class: INDUSTRY briefSummary: 1. Research Purp... |
2. Design: A dose block-randomized, double-blind, placebo controlled, single- and multiple dosing, dose-escalation phase 1 clinical trial conditions: Non-alcoholic Steatohepatitis studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE who... |
<|newrecord|> nctId: NCT06308848 id: PR-22077 briefTitle: Microbiota Directed Food for Children With Severe Acute Malnutrition overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2026-10-31 date: 2026-12-31 date: 2024-03-13 date: 2024-03-13 name: International Centre for Diarrhoeal Disease Research, Bangladesh cla... |
<|newrecord|> nctId: NCT06308835 id: APHP231652 briefTitle: Prevalence and Risk Factor of Post-intensive Care Syndrome in Neuro-ICU acronym: STRESSréa overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-08 date: 2025-08 date: 2024-03-13 date: 2024-03-18 name: Assistance Publique - Hôpitaux de Paris class: OTHER ... |
<|newrecord|> nctId: NCT06308822 id: NCI-2024-01151 id: NCI-2024-01151 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: EAY131-K1 type: OTHER domain: ECOG-ACRIN Cancer Research Group id: EAY131-K1 type: OTHER domain: CTEP id: U10CA180820 type: NIH link: https://reporter.nih.gov/quickSearch/U10CA180820... |
<|newrecord|> nctId: NCT06308809 id: Shuzhen Ma briefTitle: Effect of PNF Training as an Intervention for Functional Ankle Instability in College Student overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2024-05-30 date: 2024-06-20 date: 2024-03-13 date: 2024-03-15 name: Ma Shuzhen class: OTHER briefSummary: The... |
- Page 2 of 5 \[DRAFT\] -In order to avoid mutual interference between the experimental group and the control group, a blinding method needs to be used in the study. In this study, a single blind experiment will be conducted to blind the participating athletes. |
During the sample grouping process, participating athletes will not know the specific grouping situation. whoMasked: PARTICIPANT count: 30 type: ESTIMATED name: PNF training measure: CAIT score measure: Lower limb stability test measure: Star offset balance test measure: Muscle strength test sex: MALE minimumAge: 18 Ye... |
<|newrecord|> nctId: NCT06308796 id: RADIOCARIES2023 briefTitle: Prevention of Caries in Head and Neck Cancer Survivors Who Underwent Radiotherapy acronym: RADIOCARIES overallStatus: RECRUITING date: 2023-04-01 date: 2026-01-31 date: 2026-03-31 date: 2024-03-13 date: 2024-03-15 name: University of Milan class: OTHER br... |
<|newrecord|> nctId: NCT06308783 id: UFranciscoVitoriaRPGBREATH23 briefTitle: Diaphragmatic Breathing and Global Postural Reeducation on Stress and Sleep Quality in University Students acronym: RPGBREATH23 overallStatus: NOT_YET_RECRUITING date: 2024-05-05 date: 2024-07-17 date: 2024-07-18 date: 2024-03-13 date: 2024-0... |
Objectives: Compare the effects of a diaphragmatic breathing self-management program with global postural reeducation on stress and sleep quality in university students. |
Method: The study will be carried out with physiotherapy students of the University Francisco de Vitoria. The participants will be randomly divided into three groups: GPR group, DR group and control group. Perceived stress (Perceived Stress Scale - PSS14) and reported sleep quality (Pittsburgh Sleep Quality Index - PSQ... |
Ethical considerations: |
The principles of the 1964 Declaration of Helsinki will be followed. The proposed interventions are non-invasive, based on the combination of mild physical activity tools, body awareness and relaxation techniques. |
The dependent variables to be measured are based on clinimetric aspects, without any harm to the participants. |
Subjects will be asked to participate on a voluntary basis and may withdraw from the study at any time. conditions: Stress conditions: Sleep Disturbance studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: One group receives Diaphragmatic Breathing, one g... |
<|newrecord|> nctId: NCT06308770 id: AC21137 briefTitle: Fatigue in Lupus Intervention Programmes (FLIP) acronym: FLIP overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04 date: 2027-04 date: 2024-03-13 date: 2024-03-13 name: University of Edinburgh class: OTHER name: Accord Clinical Research briefSummary: ... |
Our study aims to establish whether a virtual group Fatigue Management Programme and a fatigue booklet (Versus Arthritis and Lupus UK) is more effective at reducing the impact of fatigue in SLE participants than the fatigue booklet alone. |
The investigators will also compare a shortened 4-week to the standard 7-week programme to lessen the time commitment for participants and potentially reduce waiting times.The investigators will measure the effectiveness of the interventions through the use of Patient Reported Outcome Measures (PROMs) at several interv... |
1. Standard care (SC) - Lupus UK and Versus Arthritis Booklets |
2. SC and 4 week Fatigue management Programme (FMP) |
3. SC and 7 week FMP Results will be measured by comparing Patient Reported Outcome measures (PROMs) submitted before and after the intervention and, at 6 and 12 months. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The statistician who analyses the results will be blind to the intervention to which the... |
<|newrecord|> nctId: NCT06308757 id: 495/2021/Sper/AOUBo briefTitle: Role of the Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Non-Alcoholic Steatohepatitis (NASH) With Fibrosis acronym: KETONASH overallStatus: RECRUITING date: 2021-09-29 date: 2024-11-24 date: 2026-12-12 date: 2024-03-13 date: 2024-03-15 na... |
<|newrecord|> nctId: NCT06308744 id: 2021-5212-4387 briefTitle: A Large Multi-site Study on Self-administered Mindfulness overallStatus: COMPLETED date: 2022-03-23 date: 2022-06-30 date: 2022-06-30 date: 2024-03-13 date: 2024-03-15 name: Swansea University class: OTHER name: Université Grenoble-Alpes name: University o... |
<|newrecord|> nctId: NCT06308731 id: 23-26 briefTitle: Exercise-Induced Rates of Fat Oxidation With and Without Ingestion of a Caffeine-Based Energy Drink acronym: EDX overallStatus: RECRUITING date: 2024-01-19 date: 2024-07-01 date: 2024-07-01 date: 2024-03-13 date: 2024-03-13 name: Lindenwood University class: OTHER ... |
<|newrecord|> nctId: NCT06308718 id: FBX-101-LTFU briefTitle: Long-term Follow-up Study to Evaluate Safety and Efficacy of FBX-101 in Krabbe Patients overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2029-12 date: 2029-12 date: 2024-03-13 date: 2024-04-26 name: Forge Biologics, Inc class: INDUSTRY briefSummary: Thi... |
<|newrecord|> nctId: NCT06308705 id: 2022-19 briefTitle: The SsRI/NIE Recombinant Antigen ELISA for the Follow up of Patients Infected by Strongyloides Stercoralis overallStatus: COMPLETED date: 2023-06-06 date: 2023-10-18 date: 2023-10-18 date: 2024-03-13 date: 2024-03-13 name: IRCCS Sacro Cuore Don Calabria di Negrar... |
The main objective of this study is to evaluate the ELISA SsIR/NIE test for the post-treatment follow-up of patients suffering from strongyloidosis, using well-characterized sera from a previous study. |
All sera available in the Tropica biobank and coming from the Strong Treat study, for which serum samples collected at baseline and at 12-month follow-up are available, will be eligible for the study. |
The test The InBios Strongy Detect TM IgG ELISA detects specific IgG antibodies against recombinant Strongyloides NIE and SsIR antigens in serum. It consists of an enzymatically amplified sandwich immunoassay. Positive and negative control samples are provided in the kit. The test will be performed and interpreted acco... |
The laboratory technicians will receive from the PI of the study a list of pseudo-anonymized sera to be tested with SsIR/NIE ELISA, they will check their availability and proceed with the test according to the Manufacturer's instructions. Laboratory personnel performing and reading the tests will be blinded to the resu... |
<|newrecord|> nctId: NCT06308692 id: 2022-11 briefTitle: Molecular Diagnostics of Bacterial Infections and Antibiotic Resistance in Blood Samples and Rectal Swabs Using Real Time PCR-ARES PCR Methods overallStatus: RECRUITING date: 2022-06-28 date: 2024-12 date: 2024-12 date: 2024-03-13 date: 2024-03-13 name: IRCCS Sac... |
The objective is to evaluate the performance for the identification of microorganisms in blood samples and rectal swabs of real time PCR assays for the targets: KPC, VIM, IMP, NDM, Acinetobacter OXA, Oxa48, MCR. |
The evaluations will be carried out taking into consideration the data obtained from the diagnostic routine at the DITM. conditions: Drug Resistant Bacterial Infection studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 100 type: ESTIMATED ... |
<|newrecord|> nctId: NCT06308679 id: BE 001-24 briefTitle: A Bioequivalence Study of Two Formulations of 10-mg Empagliflozin Tablets in Healthy Thai Volunteers Under Fasting Conditions overallStatus: NOT_YET_RECRUITING date: 2024-05-28 date: 2024-05-31 date: 2024-06-07 date: 2024-03-13 date: 2024-03-13 name: Pharma Nue... |
Primary: |
to evaluate the bioequivalence of two formulations of Empagliflozin tablets, test formulation and reference innovator formulation, after a single oral dose administration in healthy Thai subjects under fasting conditions |
Secondary: |
To examine the pharmacokinetics and safety of test and reference formulations |
Study Design: |
A Bioequivalence Study of Two Formulations of 10-mg Empagliflozin Tablets in Healthy Thai Volunteers under Fasting Conditions conditions: Healthy Vollunteer studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 28 type:... |
<|newrecord|> nctId: NCT06308666 id: 46091 briefTitle: Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use acronym: FOX overallStatus: RECRUITING date: 2024-03-18 date: 2024-07-18 date: 2024-07-18 date: 2024-03-13 date: 2024-03-22 name: U... |
<|newrecord|> nctId: NCT06308653 id: PSIL301 briefTitle: Psilocybin for Major Depressive Disorder (MDD) acronym: uAspire overallStatus: RECRUITING date: 2024-03-05 date: 2025-04 date: 2026-04 date: 2024-03-13 date: 2024-03-26 name: Usona Institute class: OTHER briefSummary: Approximately 240 eligible adult participants... |
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Psilocybin 25 mg versus placebo in adults with MDD, as assessed by the difference between groups in change in depressive symptoms from Baseline to Day 43 post-dose, and to characterize the durability of initial treatment effect and subse... |
All roles other than the Sponsor, CRO, and Ethics Committees will also be blinded to the randomization ratio and Patient Health Questionnaire-9 (PHQ-9) score for re-administration eligibility. |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.