text stringlengths 0 197k |
|---|
Exploratory outcomes |
- To describe disease progression with focus on organ involvement. |
The study design is a retrospective clinical and paraclinical follow-up of the Danish National Fabry cohort in the period 01.01.2001-31.12.2022. Patient followed a structured yearly monitoring program as part of routine clincal care. conditions: Fabry Disease studyType: OBSERVATIONAL observationalModel: COHORT timePers... |
<|newrecord|> nctId: NCT06303453 id: REC/RCR&AHS/23/0291 briefTitle: Comparative Effects of Balance and Resisted Training in Diabetic Peripheral Neuropathy. overallStatus: RECRUITING date: 2024-02-25 date: 2024-05-01 date: 2024-05-15 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER b... |
<|newrecord|> nctId: NCT06303440 id: REC/RCR&AHS/23/0288 briefTitle: Effects of Virtual Reality Training Versus Motor Imagery in Children With Cerebral Palsy overallStatus: RECRUITING date: 2024-02-25 date: 2024-05-10 date: 2024-05-25 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER ... |
<|newrecord|> nctId: NCT06303427 id: REC/RCR & AHS/23/0292 briefTitle: Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation in Erb's Palsy overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-05-01 date: 2024-05-15 date: 2024-03-12 date: 2024-03-12 name: Riphah Intern... |
<|newrecord|> nctId: NCT06303414 id: RESCO briefTitle: Revascularization for Symptomatic Non-acute Carotid Artery Occlusion acronym: RESCO overallStatus: RECRUITING date: 2016-06-17 date: 2028-12-30 date: 2028-12-30 date: 2024-03-12 date: 2024-03-12 name: Xuanwu Hospital, Beijing class: OTHER briefSummary: The short-te... |
<|newrecord|> nctId: NCT06303401 id: REC/MS-PT/01787 Gullalay briefTitle: Comparison of Thrust Manipulation of Sacroiliac Joint and Pelvic Stabilization Exercises in Post Partum Low Back Pain overallStatus: RECRUITING date: 2023-09-27 date: 2024-07-31 date: 2024-08-30 date: 2024-03-12 date: 2024-03-12 name: Riphah Inte... |
<|newrecord|> nctId: NCT06303388 id: REC/MS-PT/01721 briefTitle: Effects of Bruegger's Exercises Versus Egoscue Exercise on Lower Cross Syndrome overallStatus: RECRUITING date: 2024-02-26 date: 2024-05-30 date: 2024-06-15 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER briefSummary:... |
<|newrecord|> nctId: NCT06303375 id: REC/MS-PT/01718 Nida Kausar briefTitle: Effect of Kinesio Taping on Pain, Posture and Function in Lower Cross Syndrome overallStatus: RECRUITING date: 2023-10-13 date: 2024-07-31 date: 2024-08-30 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER br... |
<|newrecord|> nctId: NCT06303362 id: REC/MS-PT/014258 Sumbal Nawaz briefTitle: Effects of Elastic Band Excercises on Chest Expansion overallStatus: COMPLETED date: 2023-08-01 date: 2024-01-30 date: 2024-01-30 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER briefSummary: • To determi... |
<|newrecord|> nctId: NCT06303349 id: CHUBX 2023/45 briefTitle: Predictive Model for the Occurrence of Cerebral Vasospasm Complicating Subarachnoid Haemorrhage by Combined Analysis of the Kinetics of a Panel of Biomarkers. acronym: CVSBIODIAG overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2025-03 da... |
Patients admitted to intensive care will be followed for up to 14 days (D14 time horizon of interest), or until discharge from intensive care if earlier. |
Blood samples will be taken from D1 to D10 to isolate the blood biomarkers of interest for each patient. |
The measurement of biomarkers and cerebral vasospasm will be blinded to each other. conditions: Cerebral Vasospasm studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Prospective single-centre cohort study with prognostic aim, carried out in the neuro-resusc... |
<|newrecord|> nctId: NCT06303336 id: REC/0258 Ayesha Ashraf briefTitle: Effects OF NMES With and Without Dynamic Bracing on Spasticity and Movement Quality in CP overallStatus: RECRUITING date: 2023-12-30 date: 2024-05-14 date: 2024-05-14 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OT... |
<|newrecord|> nctId: NCT06303323 id: Nawal Fatima briefTitle: Comparative Effectiveness of Qigong Exercise Versus Wu Dang Tai Chi Chuan in CVD Risk Individuals overallStatus: RECRUITING date: 2024-03-15 date: 2024-07 date: 2024-08 date: 2024-03-12 date: 2024-04-03 name: Riphah International University class: OTHER brie... |
<|newrecord|> nctId: NCT06303310 id: REC/RCR&AHS/23/0296 briefTitle: Comparative Effects Of Gaze Stability Exercises And Optokinetic Exercises In Patients With Vestibular Hypofunction overallStatus: RECRUITING date: 2024-02-20 date: 2024-05-01 date: 2024-05-15 date: 2024-03-12 date: 2024-03-12 name: Riphah Internationa... |
<|newrecord|> nctId: NCT06303297 id: REC/RCR&AHS/23/0576 briefTitle: Effects of Reflexology and Generalized Stretching in Postmenopausal Females. overallStatus: RECRUITING date: 2023-11-23 date: 2024-08-01 date: 2024-09-01 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER briefSummary... |
<|newrecord|> nctId: NCT06303284 id: Pending briefTitle: Post-surgical Outcomes With Anabolic Agent Use in High-risk Ankle Fractures: A Pilot RCT overallStatus: NOT_YET_RECRUITING date: 2025-01-01 date: 2026-12-31 date: 2027-06-01 date: 2024-03-12 date: 2024-03-18 name: University of Calgary class: OTHER briefSummary: ... |
There is growing evidence to support the use of bone-building medications, such as Teriparatide, in patients who have delayed fracture healing or non-unions; however, these medications have yet to be investigated in elderly patients with ankle fractures at high risk for delayed fracture healing and post-operative compl... |
The proposed study is a pilot randomized controlled trial (RCT) with patients 60 years or older with an additional risk factor for delayed healing (i.e., osteoporosis, diabetes, vascular disease) who require ankle fracture surgery. Participants will be randomized to receive the study medication (Teriparatide) or placeb... |
This study will evaluate the novel clinical approach of augmenting surgical fixation with a medication to build bone density and strength, thereby improving bone health, preventing complications, and improving outcomes. This study will also inform planning for a larger clinical trial to reduce the morbidity, mortality,... |
<|newrecord|> nctId: NCT06303271 id: MUHAMMAD NISAR briefTitle: Transcutaneous Auricular Vagus Nerve Stimulation on Dizziness & Balance in Elderly Population overallStatus: RECRUITING date: 2024-02-01 date: 2024-06-30 date: 2024-06-30 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER ... |
<|newrecord|> nctId: NCT06303258 id: RiphahIU Sharmeen Kanwar briefTitle: Generalized Versus Core Stabilization Antenatal Exercises For Lumbopelvic Pain overallStatus: RECRUITING date: 2024-03-04 date: 2024-05-01 date: 2024-06-30 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER brief... |
<|newrecord|> nctId: NCT06303245 id: REC/RCR&AHS/23/0579 briefTitle: Effects of Abdominal Binders and TENS on Puerperium Period After Cesarean Section overallStatus: RECRUITING date: 2023-02-23 date: 2024-08-01 date: 2024-09-01 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER briefSu... |
<|newrecord|> nctId: NCT06303232 id: REC/RCR&AHS/23/0578 briefTitle: Effects of Manual Lymphatic Drainage and Therapeutic Ultrasound on Breast Engorgement overallStatus: RECRUITING date: 2023-02-23 date: 2024-08-01 date: 2024-09-01 date: 2024-03-12 date: 2024-03-12 name: Riphah International University class: OTHER bri... |
<|newrecord|> nctId: NCT06303219 id: REC/RCR&AHS/23/0577 briefTitle: Effects of Traditional Moderate Intensity Training and High Intensity Interval Training in Polycystic Ovarian Syndrome overallStatus: RECRUITING date: 2023-11-23 date: 2024-08-01 date: 2024-09-01 date: 2024-03-12 date: 2024-03-12 name: Riphah Internat... |
<|newrecord|> nctId: NCT06303206 id: H23-00623 briefTitle: TEC4Home Blood Pressure Randomized Controlled Trial overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2027-01-01 date: 2027-01-01 date: 2024-03-12 date: 2024-03-12 name: University of British Columbia class: OTHER briefSummary: The goal of this clinical ... |
The main question it aims to answer is: Does telemonitoring with case management improve BP control, relative to usual care, for people with high blood pressure discharged from the ED? |
Secondary research questions will address: |
1. How do these interventions (telemonitoring and case management) improve medication adherence? |
2. Do these interventions reduce physician and ED visits? |
3. Are these interventions safe? |
4. How do these interventions influence patient experience? |
Participants in the intervention group will receive training and use of a home BP telemonitor with tele-transmission function for 12-months plus pharmacist case management to provide behavioral counseling, facilitate medication adherence, review telemonitored BP data, and adjust medications. The control group will rece... |
<|newrecord|> nctId: NCT06303193 id: 10001554 id: 001554-C briefTitle: Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms overallStatus: NOT_YET_RECRUITING date: 2024... |
Myelodysplastic syndrome (MDS) and myelodysplastic/myeloproliferative neoplasm (MDS/MPN) are blood disorders that can cause serious complications in children and adults. MDS and MDS/MPN can also progress to acute myeloid leukemia. Treatments for these disorders are risky and not always effective. Better treatments are ... |
Objective: |
To test a study drug (pacritinib) in adults and children with MDS or MDS/MPN. |
Eligibility: |
Children (aged 12 to 17 years) and adults (aged 18 years and older) with MDS or MDS/MPN. |
Design: |
Participants will be screened. They will have a physical exam with blood tests. They will have tests of their heart function. They may have a bone marrow biopsy: An area over the hip will be numbed; a needle will be inserted to remove a sample of soft tissue from inside the hipbone. |
Pacritinib is a capsule taken by mouth. All participants will take the study drug 2 times a day, every day, in 28-day cycles. They will write down the date and time they take each capsule. Doctors will assign varying dosages of the drug to different participants. |
Participants will have clinic visits each week during cycle 1; every 2 weeks during cycle 2; and gradually increasing to every 3 months after cycle 13. Treatment will continue for up to 8 years. |
Bone marrow biopsies, heart tests, and other tests will be repeated at intervals throughout the study. Participants will also fill out questionnaires about their quality of life, the symptoms of their disease, and other topics. conditions: Myelodysplastic Syndromes studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE... |
<|newrecord|> nctId: NCT06303180 id: 10001560 id: 001560-DC briefTitle: NIDCD Otolaryngology Clinical Protocol Biospecimen Bank overallStatus: RECRUITING date: 2024-03-04 date: 2033-12-30 date: 2033-12-30 date: 2024-03-12 date: 2024-04-02 name: National Institute on Deafness and Other Communication Disorders (NIDCD) cl... |
Many disorders of the head and neck can affect a person s hearing; balance; smell; taste; swallowing; voice; or speech. These disorders include cancers and genetic and inflammatory diseases. To find better ways to diagnose and treat these disorders, researchers need to study tissues and other biological samples from pe... |
Objective: |
To collect biological samples for a repository that will be used for research. |
Eligibility: |
People of any age with a disorder of the head and neck that requires the taking of biological samples. The conditions may be any that affect hearing; balance; smell; taste; swallowing; voice; or speech. |
Design: |
Part 1: Participants will give permission for their leftover tissue samples to be used for research. These are tissue samples from the head and neck that were collected in the course of routine tests and care or other research studies. Information on each participant s age, diagnosis, and previous treatments will also ... |
Part 2: Some participants may be asked for more samples. All those aged 3 years or older will have a physical exam. They will provide blood and saliva samples. A cotton swab or brush will be used to collect cells from the inside of the cheek. |
Participants 18 years or older may have additional tests. They may provide nasal secretions: A piece of gelfoam or a sponge will be placed in the nose to soak up secretions for 5 to 10 minutes. They may have biopsies: Small samples of tissue will be cut from the skin and the tissue lining the mouth. |
Samples may be used for genetic testing. conditions: Hearing Loss conditions: Head and Neck Neoplasms conditions: Hearing Disorders conditions: Laryngeal Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1000 type: ESTIMATED measure: To create a biorepository of diseased an... |
<|newrecord|> nctId: NCT06303167 id: NCI-2024-01150 id: NCI-2024-01150 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: EAY131-E type: OTHER domain: ECOG-ACRIN Cancer Research Group id: EAY131-E type: OTHER domain: CTEP id: U10CA180820 type: NIH link: https://reporter.nih.gov/quickSearch/U10CA180820 b... |
<|newrecord|> nctId: NCT06303154 id: EC45 MOBIBRA id: ID-RCB type: OTHER domain: 2023-A01937-38 briefTitle: Evaluation of Mobiderm Intimate Bra in the Management of Breast Edema Related to Breast Cancer Treatment acronym: MOBIBRA overallStatus: RECRUITING date: 2024-03-21 date: 2025-09 date: 2025-09 date: 2024-03-12 da... |
<|newrecord|> nctId: NCT06303141 id: LUC/CPGS/PGS/20230405/001 briefTitle: Comparative Effects of Neuromuscular Training and Mobilization With Movement in Professional Athletes With Ankle Sprain overallStatus: COMPLETED date: 2023-04-05 date: 2023-09-05 date: 2023-09-10 date: 2024-03-12 date: 2024-03-12 name: Riphah In... |
<|newrecord|> nctId: NCT06303128 id: IRB-FY2024-61 briefTitle: Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge overallStatus: RECRUITING date: 2024-02-03 date: 2024-12 date: 2025-05 date: 2024-03-12 date: 2024-03-15 name: James Tarbox, MD class: OTHER name: Texas Tech Univers... |
- In penicillin-allergic patients that are at low risk of having an allergic reaction, is a one-dose oral challenge with amoxicillin (a penicillin-based antibiotic) as safe and effective as a two-dose oral challenge? |
Participants will, after being identified as having a low-risk penicillin allergy, be administered oral amoxicillin in a controlled setting and then monitored for an allergic reaction. Researchers will compare participants that took one dose of amoxicillin to participants that took two doses of amoxicillin (a small dos... |
<|newrecord|> nctId: NCT06303115 id: CSD231005 BoE briefTitle: CSD231005 Nicotine Pouch Biomarkers of Exposure overallStatus: NOT_YET_RECRUITING date: 2024-07-15 date: 2024-12-15 date: 2025-01-15 date: 2024-03-12 date: 2024-03-15 name: RAI Services Company class: INDUSTRY briefSummary: This will be a multi center open ... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.