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Subjects will be randomly assigned to one of two groups: 1.) standard of care (SOC) treatment or 2.) SOC plus a 6 week CR program. conditions: Cardiac Rehabilitation conditions: Rheumatoid Arthritis conditions: Hypertension studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryP... |
<|newrecord|> nctId: NCT06295835 id: CS-2024-0001 briefTitle: Method Comparison Study for Measuring Potassium (K) and Ionized Calcium (iCa) in Blood overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-09 date: 2024-12 date: 2024-03-06 date: 2024-03-22 name: Abbott Point of Care class: INDUSTRY briefSummary: Meth... |
<|newrecord|> nctId: NCT06295822 id: CMUH112-REC2-063 briefTitle: The Effectiveness of Chinese Medicine Nuan-gong-ye on Primary Dysmenorrhea overallStatus: RECRUITING date: 2024-03-04 date: 2025-08-31 date: 2026-02-28 date: 2024-03-06 date: 2024-04-10 name: China Medical University Hospital class: OTHER briefSummary: P... |
<|newrecord|> nctId: NCT06295809 id: V940-007 id: 2023-505712-37 type: OTHER domain: EU CT id: U1111-1292-3589 type: OTHER domain: UTN id: V940 type: OTHER domain: Merck briefTitle: A Study of (Neo)Adjuvant V940 and Pembrolizumab in Cutaneous Squamous Cell Carcinoma (V940-007) overallStatus: RECRUITING date: 2024-05-06... |
<|newrecord|> nctId: NCT06295796 id: 8527-008 id: MK-8527-008 type: OTHER domain: Merck briefTitle: A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008) overallStatus: NOT_YET_RECRUITING date: 2024-06-17 date: 2025-04-14 date: 2025-04-14 date: 2024-03-06 date: 2024-04-26 name: Merc... |
<|newrecord|> nctId: NCT06295783 id: 2023-1059 id: NCI-2024-01955 type: OTHER domain: NCI-CTRP Clinical Registry briefTitle: Prospective Evaluation of the Relation Between Different Questionnaires Measuring Radiation-induced Side-effect overallStatus: NOT_YET_RECRUITING date: 2024-08-31 date: 2025-02-01 date: 2027-02-0... |
<|newrecord|> nctId: NCT06295770 id: 23-006712 briefTitle: Obinutuzumab in Treatment of Fibrillary Glomerulonephritis overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2027-04-01 date: 2024-03-06 date: 2024-03-06 name: Mayo Clinic class: OTHER briefSummary: The purpose of this research is to lea... |
<|newrecord|> nctId: NCT06295757 id: 2023LS102 briefTitle: Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-01-01 date: 2027-01-01 date: 2024-03-06 date: 2024-03-06 name: Masonic Cancer Center, University of Minnesota class:... |
<|newrecord|> nctId: NCT06295744 id: 2023-1724 id: Protocol Version 2/5/2024 type: OTHER domain: UW Madison id: A533300 type: OTHER domain: UW Madison id: UW23114 type: REGISTRY domain: UWCCC OnCore ID briefTitle: Outcomes and Cosmesis With Whole Breast Irradiation and Boost overallStatus: RECRUITING date: 2024-04-17 d... |
<|newrecord|> nctId: NCT06295731 id: INBRX106-01-201 id: EU CT type: OTHER domain: 2024-511323-34 briefTitle: INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2029-05 date: 2029-05 date: 2024-03-06 date: 2024-03-06 name: Inhibrx, Inc. cla... |
<|newrecord|> nctId: NCT06295718 id: 2023/51 briefTitle: Tele-assessment of Functional Performance and Quality of Life in Patients With Duchenne Muscular Dystrophy: Validity and Reliability Study overallStatus: ENROLLING_BY_INVITATION date: 2023-07-01 date: 2024-03-02 date: 2024-05-10 date: 2024-03-06 date: 2024-03-06 ... |
<|newrecord|> nctId: NCT06295705 id: 5230588 briefTitle: Exploring the Effectiveness of Dance as an Intervention to Promote Social-Emotional Health in Children With Autism Spectrum Disorder (ASD) acronym: ASD overallStatus: RECRUITING date: 2024-04-02 date: 2025-04 date: 2025-04 date: 2024-03-06 date: 2024-04-11 name: ... |
<|newrecord|> nctId: NCT06295692 id: 77242113PSO3005 id: 77242113PSO3005 type: OTHER domain: Janssen Pharmaceutical K.K. briefTitle: A Study of JNJ-77242113 for the Treatment of Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis overallStatus: RECRUITING date: 2024-02-09 date: 2025-02-19 date: ... |
<|newrecord|> nctId: NCT06295679 id: 20180442 briefTitle: A Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascular Events in Chinese Participants With Atherosclerotic Cardiovascular Disease overallStatus: RECRUITING date: 2022-12-19 date: 2028-12-19 date: 2028-12-1... |
<|newrecord|> nctId: NCT06295666 id: 26.12.2018/901 briefTitle: Gingival Crevicular Fluid (GCF) Bactericidal Permeability Protein (BPI) and Interleukin (IL)-1 Beta overallStatus: COMPLETED date: 2019-02-19 date: 2019-11-25 date: 2020-01-20 date: 2024-03-06 date: 2024-03-06 name: Akdeniz University class: OTHER briefSum... |
<|newrecord|> nctId: NCT06295653 id: 7-23 briefTitle: Subepithelial Connective Tissue Graft Versus Amniotic Chorion Membrane for Peri-implant Mucosal Thickness Enhancement overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-04-30 date: 2025-04-30 date: 2024-03-06 date: 2024-03-06 name: Tanta University class:... |
<|newrecord|> nctId: NCT06295640 id: 300/2022 briefTitle: Relative Contribution of Brain Insulin Action for Postprandial Metabolism acronym: BrainInsPPM overallStatus: RECRUITING date: 2024-03-18 date: 2025-12 date: 2026-01 date: 2024-03-06 date: 2024-03-27 name: University of Ulm class: OTHER briefSummary: The goal of... |
Therefore, participants will undergo oral glucose tolerance tests combined with a double tracer dilution technique. This approach will be compared between days with insulin delivery to the brain as nasal spray and days with placebo spray. conditions: Glucose Metabolism Disorders studyType: INTERVENTIONAL phases: NA all... |
<|newrecord|> nctId: NCT06295627 id: SYSKY-2024-115-01 briefTitle: The Analysis of Factors Causing Indwelling Urinary Catheter-related Infections in ICU Patients and Their Nursing Strategies overallStatus: COMPLETED date: 2023-01-30 date: 2023-09-30 date: 2024-01-15 date: 2024-03-06 date: 2024-03-06 name: Sun Yat-Sen M... |
<|newrecord|> nctId: NCT06295614 id: SPARKL briefTitle: Study on Preliminary Safety and Efficacy of the ARC-IM Therapy to Alleviate Locomotor Deficits in People With Parkinson's Disease acronym: SPARKL overallStatus: RECRUITING date: 2024-03-01 date: 2029-04-01 date: 2029-04-01 date: 2024-03-06 date: 2024-03-12 name: E... |
<|newrecord|> nctId: NCT06295601 id: 2024/5591 briefTitle: Telerehabilitation Based Motor Imagery and Action Observation Training in Multiple Sclerosis overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2025-02-15 date: 2025-08-15 date: 2024-03-06 date: 2024-03-06 name: Inonu University class: OTHER briefSummary:... |
<|newrecord|> nctId: NCT06295588 id: STUDY00009135 id: T32CA102618 type: NIH link: https://reporter.nih.gov/quickSearch/T32CA102618 briefTitle: Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-04-15 date: 2025-04-15 date: 2024-03-06 d... |
<|newrecord|> nctId: NCT06295575 id: ZZhang briefTitle: Effect of Probiotics on Patients With Congenital Heart Disease Following Cardiopulmonary Bypass overallStatus: COMPLETED date: 2021-06-01 date: 2022-07-01 date: 2022-07-01 date: 2024-03-06 date: 2024-03-06 name: Nanjing Children's Hospital class: OTHER briefSummar... |
<|newrecord|> nctId: NCT06295562 id: CMUH112-REC3-201 briefTitle: Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-07-31 date: 2025-07-31 date: 2024-03-06 date: 2024-03-07 name: China Medical University Hospital class: OTHER br... |
<|newrecord|> nctId: NCT06295549 id: LB2304-0001 briefTitle: Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma overallStatus: RECRUITING date: 2024-03-25 date: 2026-06-30 date: 2028-06-30 date: 2024-03-06 date: 2024-03-06 name: The First Affiliated Hospital with Nan... |
<|newrecord|> nctId: NCT06295536 id: WS10363 briefTitle: Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-08 date: 2024-08 date: 2024-03-06 date: 2024-03-06 name: Essilor International class: INDUSTRY briefSummary: ... |
<|newrecord|> nctId: NCT06295523 id: STU_2019_1759_COPD briefTitle: Heat Waves and the Elderly With COPD overallStatus: RECRUITING date: 2024-01-01 date: 2025-12 date: 2025-12 date: 2024-03-06 date: 2024-03-06 name: University of Texas Southwestern Medical Center class: OTHER name: American Heart Association briefSumma... |
<|newrecord|> nctId: NCT06295510 id: CDUTCM20240223 briefTitle: Observational Study of the Association Between Food Intake and Endometrial Polyps overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-04-01 date: 2024-05-01 date: 2024-03-06 date: 2024-03-06 name: qinxiu zhang class: OTHER briefSummary: There are... |
<|newrecord|> nctId: NCT06295497 id: LC-SHIELD briefTitle: Lung Cancer Screening by Artificial Intelligence Device overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2027-06-30 date: 2027-12-31 date: 2024-03-06 date: 2024-03-06 name: Chinese University of Hong Kong class: OTHER briefSummary: Lung cancer screening... |
<|newrecord|> nctId: NCT06295484 id: 5136 briefTitle: Effect of Nasal CPAP Versus NIPPV On Diaphragm Electrical Activity (Edi) In VLBW Preterm Infants overallStatus: RECRUITING date: 2021-08-21 date: 2025-12-31 date: 2026-12-31 date: 2024-03-06 date: 2024-03-06 name: Sunnybrook Health Sciences Centre class: OTHER brief... |
In premature babies, many organ systems are not fully grown and developed, including the lungs and respiratory muscles, so they will need breathing support to help them to breathe by preventing their tiny air sacs to collapse. This support commonly done by CPAP and Non-Invasive Positive Pressure Ventilation (NIPPV) the... |
The CPAP supports the baby's immature lungs by delivering constant pressure to keep their lungs and breathing well supported. Whereas the NIPPV will use constant pressure in the background (similar to CPAP), and on top, it will give extra intermittent puffs at regular intervals to support the baby's breathing. The NIPP... |
Studies suggested that NIPPV is better than the traditional CPAP in reducing the need of the baby to need full mechanical breathing support. This might be because the investigators tend to use lower pressures with CPAP (5-8 cmH2O) compared to relatively higher pressures with NIPPV. More recently, clinicians showed the ... |
One way to measure the support that the investigators are giving to the patient with the different devices is to measure the diaphragm activity, which the investigators call the Edi signal, using a special feeding catheter and a specific machine to measure it. The catheter is placed and used as a routine feeding tube b... |
Study duration will be 6 hours from the time of catheter insertion to fit into feeding and handling plans. Upon completion or termination of the study protocol, your baby will be put back to the originally prescribed breathing support. |
Routine monitoring for oxygen saturation, heart rate, and respiratory rate will be continued as per the standard of practice in the NICU. primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 24 type: ESTIMATED name: Alternating traditional CPAP, NIPPV, and high CPAP measure: The differences in Electrical Activity of th... |
<|newrecord|> nctId: NCT06295471 id: 2024P000112 briefTitle: A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-08 date: 2024-08 date: 2024-03-06 date: 2024-03-06 name: Massachusetts ... |
<|newrecord|> nctId: NCT06295458 id: STUDY00006945 briefTitle: Gamma Sensory Flicker for Parkinson's Disease Patients With Freezing of Gait acronym: Flicker w FOG overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-06 date: 2025-06 date: 2024-03-06 date: 2024-03-06 name: Emory University class: OTHER name: Parki... |
Based on previous animal studies this gamma stimulus has the potential as a novel, non-invasive, non-pharmacological approach, to remove amyloid from the brain. The investigators have found in a prior study, that amyloid levels are high in the spinal fluid of Parkinson's patients with FOG. |
Parkinson's disease (PD) patients often experience a complex gait disorder known as Freezing of Gait (FOG). FOG is characterized by brief arrests of stepping when initiating gait, turning, and walking straight and patients describe it as their feet being "glued" to the floor. FOG in Parkinson's disease (PD) is a consid... |
FOG is generally found to be associated with cognitive decline, particularly executive dysfunction which, in turn, has been associated with higher spinal fluid amyloid (Aβ42) levels in PD. conditions: Gait Disorders, Neurologic conditions: Parkinson Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED in... |
<|newrecord|> nctId: NCT06295445 id: Cardiopulmonary Ultrasound briefTitle: Impact of Integrated Cardiopulmonary Ultrasound on Clinical Outcome of Shocked Patients in Intensive Care Unit overallStatus: COMPLETED date: 2022-03-01 date: 2023-09-01 date: 2023-09-15 date: 2024-03-06 date: 2024-03-12 name: Egymedicalpedia c... |
<|newrecord|> nctId: NCT06295432 id: DZ2022E0001 briefTitle: A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21) overallStatus: RECRUITING date: 2023-06-01 date: 2025-06 date: 2025-06 date: 2024-03-06 date: 2024-03-20 name: Dizal P... |
<|newrecord|> nctId: NCT06295419 id: Igdir182 briefTitle: The Effect of Dual Task on Manual Ability Performance in Children With Cerebral Palsy overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-07-01 date: 2024-08-01 date: 2024-03-06 date: 2024-03-08 name: Igdir University class: OTHER briefSummary: The aim... |
Evaluations to be made in the study (children with CP) and control (typically developing peers) groups: |
* Demographic information, Gross Motor Function Level (GMFCS), Manual Skills Classification System (MACS) and dominant extremity will be noted and the evaluation will begin by applying the Abilhand Kids questionnaire. |
* Firstly, the child's performance on a single cognitive task will be evaluated in a supported sitting position on a chair. The cognitive task will be the n-back task (counting down task) to be applied in accordance with the level of the child or young person. |
* Using the Visual Analogue Scale (VAS), participants will be asked to score the difficulty of the cognitive task as a number between 0 and 10. |
* In order to evaluate the single motor performance of manual skills, the 9-Hole Test will be applied and the times will be recorded by asking to write a given paragraph. |
* Dual task evaluations will be administered by giving a simultaneous cognitive task while administering the 9-Hole Test and writing a paragraph. |
* In order to reveal the dual-task cost (DTC), dual-task performance will be subtracted from single-task performance and the difference will be calculated in seconds. |
* The Body Control Measurement Scale will be applied for body evaluation purposes. |
As a result of this study, the changes in manual dexterity and cognitive performance in dual-task conditions in children and adolescents with CP will be revealed. Additionally, changes in this performance in dual-task situations will be compared with a control group of typically developing children. conditions: Cerebra... |
<|newrecord|> nctId: NCT06295406 id: 21C310 briefTitle: Reading Ability in Childhood Obesity acronym: Lettura_evOB overallStatus: RECRUITING date: 2023-12-01 date: 2025-11-30 date: 2025-11-30 date: 2024-03-06 date: 2024-03-08 name: Istituto Auxologico Italiano class: OTHER briefSummary: There is some evidence about the... |
In this neuropsychological research, the relationship between the characteristics of reading abilities in individuals with obesity (age range between 11 and 16 years) and the skills of motor coordination, postural stability, manual dexterity, including graphomotor skills, and estimation of time is investigated accordin... |
<|newrecord|> nctId: NCT06295393 id: 20-0229-CCMC briefTitle: Renin Angiotensin Aldosterone System In Septic Kids acronym: RISK overallStatus: RECRUITING date: 2024-01-24 date: 2025-06-01 date: 2025-06-01 date: 2024-03-06 date: 2024-03-06 name: Northwell Health class: OTHER briefSummary: Prospective observational cohor... |
Blood samples and renal ultrasound will be collected on sequential days for septic subject and one time for the healthy patients. |
Enzyme-linked immunosorbent assays (ELISA) with be run on serum plasma to compare the renin-angiotensin-aldosterone system (RAAS) between groups. conditions: Sepsis conditions: Acute Kidney Injury Due to Sepsis conditions: Acute Kidney Injury (Nontraumatic) studyType: OBSERVATIONAL observationalModel: COHORT timePerspe... |
<|newrecord|> nctId: NCT06295380 id: CarenAmp briefTitle: Virtual Reality Rehabilitation to Promote Motor Recovery in Amputees overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-09 date: 2025-03 date: 2024-03-06 date: 2024-03-06 name: IRCCS Centro Neurolesi "Bonino-Pulejo" class: OTHER briefSummary: Interventio... |
<|newrecord|> nctId: NCT06295367 id: EAQ222CD id: NCI-2023-09944 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: EAQ222CD type: OTHER domain: ECOG-ACRIN Cancer Research Group id: ECOG-ACRIN-EAQ222CD type: OTHER domain: DCP id: EAQ222CD type: OTHER domain: CTEP id: R01CA272680 type: NIH link: https://... |
<|newrecord|> nctId: NCT06295354 id: 2024-17062 briefTitle: Early Variations in Immune Aging acronym: EVIA-NL overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2028-12 date: 2028-12 date: 2024-03-06 date: 2024-03-06 name: Radboud University Medical Center class: OTHER briefSummary: Background: |
Despite an increase in lifespan over the last decades, our healthspan lags behind. In our aging population, it is pressing that we prevent age-related morbidities and associated burden on the health care system. Instead of investigating aging in already aged populations, the currently proposed study aims to elucidate t... |
Study design: |
A single-center, observational prospective cohort study in the Netherlands. Participants from priorly established cohorts will be invited to join the EVIA-study. We will obtain demographic and basic clinical data and biological samples (blood and stool) at baseline and after three years, with a short, yearly online que... |
<|newrecord|> nctId: NCT06295341 id: 01C312 briefTitle: Short Stature and Psychological Well-being acronym: PSICOSHORT overallStatus: RECRUITING date: 2023-05-10 date: 2024-12-31 date: 2024-12-31 date: 2024-03-06 date: 2024-03-06 name: Istituto Auxologico Italiano class: OTHER briefSummary: The first aim of the present... |
<|newrecord|> nctId: NCT06295328 id: NL 72439.018.19 briefTitle: From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patients acronym: HepBTer overallStatus: RECRUITING date: 2022-04-13 date: 2024-04-01 date: 2024-04-01 date: 2024-03-06 date: 2024-03-06 name: Academisch Med... |
Objective: to provide proof of concept for the inhibition of HBx mediated cccDNA transcription by terbinafine, both as monotherapy and add-on therapy next to tenofovir. Secondary outcomes will be the safety and tolerability of terbinafine in this specific group. |
Study design: This pilot study is a stratified, single center, randomized, double-blinded, placebo-controlled, dose-ascending proof of concept clinical trial. |
Study population: patients chronically infected with the hepatitis B virus with a normal liver function and no signs of liver damage, who do not use any antiviral medication (group A, n=16) or are treated with tenofovir \> 6 months (group B, n=16). |
Intervention: Patients will be randomly allocated to daily oral treatment with terbinafine or a matched placebo, either as monotherapy (group A) or as add-on therapy to tenofovir (group B). |
Main study parameters/endpoints: Primary outcomes: decline in level of serum HBsAg \>0.32log10 IU/mL in both groups A and B and decline in serum HBV DNA \>0.86log10 in group A at the end of study treatment (week 10 vs baseline). Secondary outcomes: 1) Safety and tolerability of terbinafine as mono- or combination thera... |
Nature and extent of the burden and risks associated with participation, benefit and group relatedness: Patients participating in this study will undergo physical examinations and blood sample collections (13 samples and in total 467.5 mL). They will also be asked to fill in the HBQOL and EQ5D5L quality of life questio... |
<|newrecord|> nctId: NCT06295315 id: 01C310 briefTitle: Evaluation of the Psychological Profile of Adult Patients With Prader-Willi Syndrome acronym: PROPSICOPWS overallStatus: RECRUITING date: 2023-04-21 date: 2024-12-31 date: 2024-12-31 date: 2024-03-06 date: 2024-03-06 name: Istituto Auxologico Italiano class: OTHER... |
<|newrecord|> nctId: NCT06295302 id: RFCU-IIa-202308 briefTitle: A Study to Explore the Efficacy and Safety of HWH486 in Adults With Chronic Spontaneous Urticaria overallStatus: RECRUITING date: 2023-12-13 date: 2025-12 date: 2026-01 date: 2024-03-06 date: 2024-03-07 name: Hubei Biological Medicine Industrial Technolog... |
<|newrecord|> nctId: NCT06295289 id: ZRKY-2023-04 briefTitle: Hybrid Closed-loop Insulin Delivery System in Perioperative Diabetic Patients: an Open-label, Randomized Controlled Trial overallStatus: RECRUITING date: 2023-10-16 date: 2024-10-04 date: 2024-12-04 date: 2024-03-06 date: 2024-03-06 name: Huazhong University... |
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