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1. Evaluation of restoration quality based on the glass ionomer restoration criteria (simplified FDI criteria) |
2. Evaluation of restoration wear based on comparison of digital impressions |
Safety Endpoint: |
1. Evaluation of potential adverse events NULL HYPOTHESIS There is no statistically significant difference between both glass ionomers |
* regarding overall survival |
* regarding restoration quality parameters TEST GROUP Ketac Universal Aplicap Glass Ionomer Restorative (3M) CONTROL GROUP Ketac Molar Quick Aplicap Glass Ionomer Restorative (3M) |
* regarding restoration wear METHODS AND MATERIALS A total of 39 subjects were enrolled and treated. The study was originally planned with 80 patients. Due to slow recruitment, it was decided to decrease the number of patients. |
Treatment: |
After signing informed consent, test and control product were randomly assigned to the two study teeth (randomization letter). Restoration extension (e.g. mod) and reason for restoration placement (e.g. secondary caries, tooth fracture) were recorded in the CRF. Two teeth per subject were included. Each product was use... |
Evaluation periods: |
All subjects were evaluated by two independent evaluators according to Performance Criteria for Posterior Glass Ionomer Restorations (simplified FDI criteria) |
* at baseline at day of restoration placement or up to 1 month after restoration placement |
* after 6 months (± 1 months) |
* after 1 year (± 1 months) |
* after 2 years (± 1 months) In addition, photos (at least occlusal view) were taken of every study tooth prior to restoration placement and at every evaluation. |
In order to further assess the wear of both restorative materials, full arch digital impressions (both upper and lower jaw) were taken at baseline evaluation and at every following evaluation using 3M True Definition Scanner. STL files were digitally compared to those taken at baseline. conditions: Tooth Wear condition... |
<|newrecord|> nctId: NCT06275568 id: HSC-SPH-23-0655 briefTitle: Accelerating Healthcare Engagement in Healthy Food Interventions - Food Rx in High Risk Pregnant Mothers With About Fresh and Texas Children's Health Plan overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-11-15 date: 2024-11-15 date: 2024-02-2... |
<|newrecord|> nctId: NCT06275555 id: 2023-101 briefTitle: Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-12-31 date: 2024-02-23 date: 2024-02-26 name: Xiaotong Hou class: OTHER briefSummary: The p... |
<|newrecord|> nctId: NCT06275542 id: USurabaya briefTitle: Ability to Maintain Saturation Levels Without Oxygen Supplementation as a Extubation Criteria Without TOF Monitoring Equipment overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-01 date: 2026-01-01 date: 2024-02-23 date: 2024-02-23 name: Universit... |
* Comparison 1: The volatile anesthetic gas used was sevoflurane and the muscular blockade agent used was rocuronium. |
* Comparison 2: The volatile anesthetic gas used was isoflurane and the muscular blockade agent used was rocuronium. |
* Comparison 3: The volatile anesthetic gas used was sevoflurane and the muscular blockade agent used was atracurium. primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: Upon arrival in the recovery room, all subjects were fitted with SpO2, EKG, NIBP monitors, and the TOF monitoring device. TOF values were m... |
<|newrecord|> nctId: NCT06275529 id: 27.12.2023.685 briefTitle: Evaluation of Transforaminal Epidural Steroid Injection in Radicular Low Back Pain According to MSU Classification overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-06-15 date: 2024-08-15 date: 2024-02-23 date: 2024-02-23 name: Başakşehir Çam &... |
The aim of this study to evaluate the pain and oswestry disability index in patients who have radiculopathy with low back pain, undergone TFSI according to MSU classification. conditions: Radiculopathy Lumbar conditions: Low Back Pain conditions: Disc Herniation conditions: Injections, Epidural studyType: INTERVENTIONA... |
<|newrecord|> nctId: NCT06275516 id: 2024-208 briefTitle: Safety and Efficacy of Multisensory Stimulation Virtual Reality for Stroke Patients. overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2024-06-20 date: 2024-09-20 date: 2024-02-23 date: 2024-02-23 name: First Affiliated Hospital of Chongqing Medical Unive... |
<|newrecord|> nctId: NCT06275503 id: STROKESTOP III briefTitle: STROKESTOP III - Optimized Method for Atrial Fibrillation Screening overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2025-02-28 date: 2026-06-30 date: 2024-02-23 date: 2024-02-23 name: Danderyd Hospital class: OTHER name: Karolinska Institutet name... |
Screening for atrial fibrillation in elderly populations above age 65 years can result in detection of new atrial fibrillation cases ranging from 0,5% new AF with a single time-point ECG, up to 30% AF if an implantable loop recorder is inserted for 3 years. |
Currently opportunistic screening using pulse palpation, or a single time-point ECG is recommended by the European Society of Cardiology guidelines. Systematic screening in individuals aged 75 or above, or at a high stroke risk should be considered. |
Overall, participation in systematic atrial fibrillation screening trials has been shown to be relatively low with almost 50% non-participants. Participants are generally healthier, with higher socioeconomic status, hence the ones who would potentially benefit the most remain absent. |
Opportunistic screening has shown promising results with higher participation rates and the possibility of better outreach. There is a lack of data from randomized trials on the difference in participation rates in systematic and opportunistic screening approaches when screening with prolonged ECG monitoring. condition... |
<|newrecord|> nctId: NCT06275490 id: 181123PER6_3_1 briefTitle: Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block overallStatus: RECRUITING date: 2024-01-01 date: 2024-05-01 date: 2024-11-15 date: 2024-02-23 date: 2024-02-23 name: Cairo University class:... |
* The main question: In patients with un restorable tooth, Will ridge preservation using partially demineralized dentin block be more effective than L-PRF block in managing the post extraction hard tissue alterations? |
* After enrolment, periodontal and radiographic examination and patients with badly un-restorative tooth in the esthetic zone will be identified. These patients will undergo to mesio-distal distance between adjacent teeth, corono-apical height of bone, presence of labial undercut, dehiscence, or fenestration and Relati... |
* In both groups, the desired tooth will be extracted under local anesthesia using peritomies and surgical forceps. |
* In intervention group: the teeth will be cleaned and dried, and then the dentin will be ground to obtain particles of a certain size then partially demineralize dentin will obtained by using a tooth transformer machine. At the same time, blood samples are collected and processed to obtain fibrin membranes rich in pla... |
* In control group: the same steps as the first group will be used, but by replacing the partially demineralized dental graft with a xenograft. |
* Outcomes: Radiographic vertical buccal bone changes, vertical Palatal bone changes, horizontal bone changes, Percentage of new vital bone formation, Percentage of residual bone graft, Implant Primary Stability. The results directly postoperative and 4-6 months postoperatively. conditions: Socket Preservation studyTyp... |
<|newrecord|> nctId: NCT06275477 id: 29BRC23.0029 briefTitle: 68Gallium-FAPI PET/CT Imaging in Chronic Inflammatory and Fibrotic Diseases acronym: PARADISE overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-21 date: 2026-04-21 date: 2024-02-23 date: 2024-02-23 name: University Hospital, Brest class: OTHER... |
<|newrecord|> nctId: NCT06275464 id: BT-600-101 briefTitle: BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult Subjects overallStatus: RECRUITING date: 2024-01-11 date: 2024-04 date: 2024-06 date: 2024-02-23 date: 2024-02-23 name: Biora Therapeutics, Inc. class: INDUSTRY briefSummary: This is a randomized... |
The purposes of this study are to learn about the safety and tolerability of single and multiple rising oral doses of BT-600, assess the blood and tissue levels of tofacitinib released from BT-600, and assess the body's effects to the study drug following oral doses of BT-600 in blood and tissue in healthy adult partic... |
BT-600 is a swallowable drug/device combination product designed to deliver a liquid formulation of tofacitinib to the colon and dispense the study drug throughout the colon. BT-600 consists of two components, the drug part containing a reservoir, which will be filled with liquid tofacitinib, and the drive part. The dr... |
<|newrecord|> nctId: NCT06275451 id: EssaiClinique_QUALI-RES briefTitle: Qualitative Study of Emotional Regulation in Schizophrenia acronym: QUALI-RES overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-01 date: 2026-01 date: 2024-02-23 date: 2024-02-28 name: University Hospital, Grenoble class: OTHER briefSumma... |
Given the qualitative nature of the methodology used in this study, the investigators have no specific hypothesis. The investigators have a general hypothesis suggesting that the patients' discourse will enable us to highlight the emotional regulation difficulties described in the literature. conditions: Schizophrenia ... |
<|newrecord|> nctId: NCT06275438 id: 81829502.903/39 briefTitle: Comparison of Oxytocin Receptor Immunoreactivity in Placentas Obtained From Women Having Cesarean and Natural Birth overallStatus: COMPLETED date: 2018-08-25 date: 2019-07-01 date: 2019-12-01 date: 2024-02-23 date: 2024-02-23 name: Kafkas University class... |
<|newrecord|> nctId: NCT06275425 id: 4-2023-0429 briefTitle: Comparison of the Coughing Frequency of Remimazolam Total Intravenous Anesthesia Versus Inhalational Anesthesia overallStatus: COMPLETED date: 2023-06-25 date: 2023-11-29 date: 2023-11-29 date: 2024-02-23 date: 2024-02-23 name: Yonsei University class: OTHER ... |
The primary end point of the study is to determine whether coughing during endotracheal tube extubation is less when anesthesia is maintained with intravenous remimazolam compared to inhalation anesthetics. The secondary end points are cough score (graded into 4 levels), frequency of reoperation due to postoperative bl... |
<|newrecord|> nctId: NCT06275412 id: IRB-23-04-5675 id: 5R01MD018583-02 type: NIH link: https://reporter.nih.gov/quickSearch/5R01MD018583-02 briefTitle: Family Intervention for Black Teens With Type 1 Diabetes acronym: 3Ms overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2028-03 date: 2028-03 date: 2024-02-23 date... |
<|newrecord|> nctId: NCT06275399 id: INTERFORCE briefTitle: Comprehensive Assessment of Morphometric, Functional, Biomechanical and Biological Interactions Between Atherosclerotic Plaque and Platelets Within the Stenosed Coronary Artery acronym: INTERFORCE overallStatus: RECRUITING date: 2023-07-21 date: 2025-07-21 dat... |
<|newrecord|> nctId: NCT06275386 id: 2.31/II/24 briefTitle: Drug-Coated Balloon in Native Chronic Total Occlusion Percutaneous Coronary Intervention acronym: IMAGINATION overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-09-01 date: 2025-09-01 date: 2024-02-23 date: 2024-02-23 name: National Institute of Car... |
<|newrecord|> nctId: NCT06275373 id: 20-10974 briefTitle: The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction acronym: Teprotumumab overallStatus: RECRUITING date: 2021-05-12 date: 2026-05-12 date: 2027-12-12 date: 2024-02-23 date: 2024-02-23 name: Walter Reed National Military Medical Center clas... |
<|newrecord|> nctId: NCT06275360 id: SPLP-002-23F briefTitle: Repositioning Immunotherapy in VetArans With Lung Cancer acronym: RIVAL overallStatus: RECRUITING date: 2024-03-01 date: 2027-02-28 date: 2030-03-31 date: 2024-02-23 date: 2024-03-12 name: VA Office of Research and Development class: FED briefSummary: This s... |
<|newrecord|> nctId: NCT06275347 id: 19CI 30 087 041 id: 1/1142021 type: OTHER domain: Comite del Centro de alta especialidad del Estado de Veracruz briefTitle: Very Low Calorie Ketogenic Low-fat Diet (VLCKLFD) acronym: Zelé2021 overallStatus: COMPLETED date: 2021-01-15 date: 2021-12-30 date: 2023-05-25 date: 2024-02-2... |
<|newrecord|> nctId: NCT06275334 id: 9133 briefTitle: Dinutuximab Beta at the HUS and the Toulouse Oncopole acronym: DNB overallStatus: RECRUITING date: 2023-11-28 date: 2024-11 date: 2024-11-28 date: 2024-02-23 date: 2024-02-23 name: University Hospital, Strasbourg, France class: OTHER briefSummary: In this study the ... |
<|newrecord|> nctId: NCT06275321 id: Elena Garcia Roca briefTitle: Physical Exercise Benefits for Cancer Patients overallStatus: RECRUITING date: 2021-11-05 date: 2024-07-27 date: 2025-07-30 date: 2024-02-23 date: 2024-02-23 name: Universitat Jaume I class: OTHER briefSummary: The purpose of the study was to analyze th... |
<|newrecord|> nctId: NCT06275308 id: STUDY21100163 briefTitle: Effect of Raised End-Tidal pCo2 on Choroidal Volume overallStatus: RECRUITING date: 2023-02-27 date: 2025-02-27 date: 2025-02-27 date: 2024-02-23 date: 2024-02-23 name: University of Pittsburgh class: OTHER briefSummary: This study is to investigate the rel... |
<|newrecord|> nctId: NCT06275295 id: ZRJY2021-BJ08-03-01-01 briefTitle: A Retrospective Study of Transbronchial Cryobiopsy in the Diagnosis of Progressive Pulmonary Fibrosis overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2024-12-24 date: 2024-12-31 date: 2024-02-23 date: 2024-02-23 name: China-Japan Friendshi... |
<|newrecord|> nctId: NCT06275282 id: HUM00235849 briefTitle: Regenerative Peripheral Nerve Interfaces for the Control of Above-knee Prostheses overallStatus: RECRUITING date: 2024-03-01 date: 2027-06-30 date: 2027-09-30 date: 2024-02-23 date: 2024-03-25 name: University of Michigan class: OTHER name: United States Depa... |
The main questions it aims to answer are: |
1. Can the amplitude, movement specificity and stability of sciatic nerve RPNI electromyography (EMG) signals be detected up to one year post RPNI surgery? |
2. Do RPNIs contain information to enable control of a physical motorized prosthetic leg with multiple degrees of freedom? |
3. Does stimulation of sciatic nerve RPNIs provides meaningful sensory feedback? |
Consenting participants with unilateral transfemoral amputation (TFA) will: |
1. Undergo RPNI surgery and electrode implantation in the residual limb. |
2. Attend regular follow-up visits following surgery to assess the health and signal strength of the RPNIs and their ability to use a prescribed prosthesis between 3- and 12-months following implantation. |
3. Undergo explantation of electrodes following the conclusion of data collection. conditions: Amputation conditions: Prostheses and Implants studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: BASIC_SCIENCE masking: NONE count: 3 type: ESTIMATED name: Intramuscular elect... |
<|newrecord|> nctId: NCT06275269 id: ZRJY2021-BJ08-04-02 briefTitle: Endoscopic Mucosal Injection Versus Ultrasound-Guided Injection of Triamcinolone to Treat Subglottic Stenosis overallStatus: NOT_YET_RECRUITING date: 2024-03-10 date: 2024-10-31 date: 2024-12-31 date: 2024-02-23 date: 2024-02-23 name: China-Japan Frie... |
<|newrecord|> nctId: NCT06275256 id: HS26226 briefTitle: Outcomes of MIST for BPH: A Single-Institution Prospective Study overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2025-03 date: 2024-02-23 date: 2024-02-23 name: University of Manitoba class: OTHER briefSummary: The investigators wish to perfor... |
<|newrecord|> nctId: NCT06275243 id: ETICA-ULE-021-2022 briefTitle: Polymorphism of ApoE in Alzheimer's Disease: Genetic Study in Castile and Leon (Spain) overallStatus: ACTIVE_NOT_RECRUITING date: 2022-07-06 date: 2023-03-13 date: 2024-03-22 date: 2024-02-23 date: 2024-02-23 name: Universidad de León class: OTHER name... |
The main questions it aims to answer are: |
* What are the allelic frequencies of ApoE variants in the population of individuals with Alzheimer's disease in Castile and Leon? |
* Is there a correlation between the ApoE4 variant and the lipid profile in the blood of individuals with Alzheimer's disease in this region? conditions: Alzheimer Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: It is a longitudinal randomise... |
<|newrecord|> nctId: NCT06275230 id: ZRJY2021-BJ08-02-07 briefTitle: Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2025-12-31 date: 2025-12-31 date: 2024-02-23 date: 2024-02-23 name: China-Japan Friendship Hospital c... |
* Can human lung stem cell proliferate in vitro. |
* Can a lung organoid derived from patients with COPD be established. Participants will be sampled during pulmonary bronchoscope for organoid establishment. conditions: Chronic Obstructive Pulmonary Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 30 type: ESTIMATED me... |
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