text
stringlengths
0
197k
* If taking the supplement for 16 days improves exercise performance, or the speed with which the body responds to the commencement of exercise.
* If taking the supplement improves cognitive function.
Participants will visit the lab on 5 separate occasions to:
* complete some cognitive tests
* complete exercise performance tests
* provide blood samples
All exercise tests will be on an exercise bike.
After 28 (or 46 for pre-menopausal females) days to make sure the supplement has left the body fully, participants will consume the opposite supplement and repeat the tests. conditions: Exercise Performance conditions: Cognitive Function studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CRO...
<|newrecord|> nctId: NCT06374628 id: 0001 briefTitle: Pre-pectoral Tissue Expander and Acellular Dermal Matrix for a Two-stage Muscle Sparing Breast Reconstruction overallStatus: RECRUITING date: 2019-06-01 date: 2024-04-01 date: 2024-12-31 date: 2024-04-18 date: 2024-04-18 name: Rossella Elia, MD PhD class: OTHER brie...
<|newrecord|> nctId: NCT06374615 id: 2024-07 briefTitle: Insights Into Tick-Borne Diseases: a Study From an Endemic Area of Northern Italy acronym: TICKTOC overallStatus: RECRUITING date: 2024-03-25 date: 2029-03 date: 2029-03 date: 2024-04-18 date: 2024-04-18 name: IRCCS Sacro Cuore Don Calabria di Negrar class: OTHER...
The study is experimental because all the visits and blood withdrawals foreseen by the protocol do not fall within the normal clinical practice. conditions: Tick-Borne Diseases studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 384 type: E...
<|newrecord|> nctId: NCT06374602 id: 33 briefTitle: Efficacy of Pembrolizumab and Lenvatinib in Patients With Anaplastic Thyroid Cancer overallStatus: RECRUITING date: 2024-03-25 date: 2026-03-25 date: 2026-06-25 date: 2024-04-18 date: 2024-04-18 name: Saint Petersburg State University, Russia class: OTHER briefSummary...
<|newrecord|> nctId: NCT06374589 id: 202303123 briefTitle: Closed-Loop O2 Use During High Flow Oxygen Treatment Of Critical Care Adult Patients (CLOUDHFOT) acronym: CLOUDHFOT overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-21 date: 2024-08-30 date: 2024-12-30 date: 2024-04-18 date: 2024-04-18 name: Başakşehir Çam & ...
As hyperoxia is considered not desirable \[Barbateskovic et al, 2019\] during any oxygen therapy, the inspired O2 concentration is usually adapted to a pre-set SpO2 target-range of 92-96% in patients without hypercapnia risk, and of 88-92% if a risk of hypercapnia is present \[O'Driscoll et al, 2017; Beasley et al, 201...
A new closed loop oxygen controller designed for HFNO was recently developed (Hamilton Medical, Bonaduz, Switzerland). The clinician sets SpO2 targets, and the software option adjusts FiO2 to keep SpO2 within the target ranges. The software option offers some alarms on low and high SpO2 and high FiO2. Given the capabil...
A short-term (4 hours vs 4 hours) crossover study indicated that this technique improves the time spent within SpO2 pre-defined target for ICU patients receiving high-flow nasal oxygen therapy \[Roca et al, 2022\]. Due to its simplicity, HFNO is increasingly used outside the ICU during transport and in the Emergency Ro...
The hypothesis of the study is that closed loop oxygen control increases the time spent within clinically targeted SpO2 ranges and decreases the time spent outside clinical target SpO2 ranges as compared to manual oxygen control in ER patients treated with HFNO. conditions: Acute Hypoxemic Respiratory Failure condition...
<|newrecord|> nctId: NCT06374576 id: GCIEL briefTitle: Improving eHealth Literacy of Older Adults in Hong Kong overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-06 date: 2024-12 date: 2024-04-18 date: 2024-04-18 name: The University of Hong Kong class: OTHER name: Sino Group name: NG TENG FONG Charitable Found...
<|newrecord|> nctId: NCT06374563 id: BUC-IACUC-221109-6 briefTitle: Tackling Pressure Ulcer Via Bee Venom Phonophoresis acronym: ulcer overallStatus: COMPLETED date: 2022-11-09 date: 2024-01-01 date: 2024-03-01 date: 2024-04-18 date: 2024-04-18 name: Badr University class: OTHER briefSummary: This study aimed to invest...
<|newrecord|> nctId: NCT06374550 id: 20231026 briefTitle: Jump Start on the Go: Improving Resiliency and the Social-Emotional Development of At-Risk Preschool Children overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-12-01 date: 2025-12-01 date: 2024-04-18 date: 2024-04-18 name: University of Miami class: ...
<|newrecord|> nctId: NCT06374537 id: 2017-0784 briefTitle: Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients. overallStatus: RECRUITING date: 2019-05-22 date: 2026-05-22 date: 2027-05 date: 2024-04-18 date: 2024-04-22 name: University of Illinois at Chicago class: OTHER brief...
<|newrecord|> nctId: NCT06374524 id: R24-03 briefTitle: Greater Occipital Nerve Block for Spontaneous Intracranial Hypotension overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2026-02-01 date: 2026-06-01 date: 2024-04-18 date: 2024-04-18 name: University Health Network, Toronto class: OTHER briefSummary: SIH is...
Treatment of SIH usually starts with conservative measures, consisting of strict supine bed rest, hydration, caffeine, and simple analgesics (3). The vast majority of patients will require invasive treatments for their CSF leak, such as epidural blood patches, fibrin glue patches, endovascular coiling, and/or surgical ...
The GONB has been reported as a simple, safe, and effective treatment to provide short-to-intermediate term relief of migraine (6), cervicogenic headache, cluster headache (7), occipital neuralgia, and more recently, post-dural puncture headaches (PDPH) (8). As the pathophysiology of intracranial hypotension caused by ...
We propose to do a prospective observational study to explore the outcome of GONB for SIH. GONB can serve as a bridge therapy to control the debilitating headache of SIH while patients are awaiting permanent SIH treatment. Moreover, GONB can be performed by physicians of different specialties including neurology, which...
<|newrecord|> nctId: NCT06374511 id: NFEC-2023-546 briefTitle: Prospective Cohort Study of Complications and Outcomes in Cirrhosis overallStatus: RECRUITING date: 2024-01-01 date: 2024-04-04 date: 2025-12-31 date: 2024-04-18 date: 2024-04-18 name: Nanfang Hospital, Southern Medical University class: OTHER briefSummary:...
<|newrecord|> nctId: NCT06374498 id: 2023P003247 briefTitle: Study to Determine the Clinical Significance of Intravascular OCT-NIRAF overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2026-04-30 date: 2027-04-30 date: 2024-04-18 date: 2024-04-18 name: Massachusetts General Hospital class: OTHER briefSummary: Pati...
1. NIRAF coronary artery signal level (patient, artery, lesion basis) is correlated with the severity of coronary artery disease.
2. NIRAF coronary artery signal level is a predictor of plaque progression on a per patient, per artery, or per lesion basis. conditions: Cardiovascular Diseases conditions: Coronary Artery Disease studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: BASIC_SCIENCE masking:...
<|newrecord|> nctId: NCT06374485 id: AU409-LEES-2021-03 briefTitle: Study of AU409 Capsule in Advanced Hepatocellular Carcinoma Patients Who Failed Standard Treatment overallStatus: RECRUITING date: 2024-04-12 date: 2026-02-28 date: 2026-08-28 date: 2024-04-18 date: 2024-04-18 name: Lee's Pharmaceutical Limited class: ...
<|newrecord|> nctId: NCT06374472 id: IRB00001194 briefTitle: Surgical Treatment of Fractures of the Dorso-lombar Spine overallStatus: COMPLETED date: 2018-01-01 date: 2022-01-01 date: 2022-01-01 date: 2024-04-18 date: 2024-04-18 name: Ibn Jazzar Hospital class: OTHER briefSummary: Trauma to the thoracolumbar spine is r...
<|newrecord|> nctId: NCT06374459 id: 24-x109 id: BC200714 type: OTHER_GRANT domain: Department of Defense briefTitle: Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis overallStatus: NOT_YET_RECRUITING date: 2024-07-3...
<|newrecord|> nctId: NCT06374446 id: 22-172 briefTitle: Effect of Virtual Reality in Patients With Long Covid-19 overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2024-06-15 date: 2024-06-30 date: 2024-04-18 date: 2024-04-18 name: Istinye University class: OTHER briefSummary: SARS-CoV-2 was first detected in Wuh...
Covid-19 infection is transmitted through droplets during coughing and sneezing and through contact with the mouth, nose or eyes after contaminated hands. The most obvious symptoms of Covid-19 symptoms include cough, dyspnea and fever. Covid-19, which can also be seen asymptomatic, is in intensive care it may be severe...
Long-term Covid or Chronic Post Covid Syndrome are multi-system syndromes that last more than 12 weeks and physical, cognitive, psychological, social and occupational domains. The most commonly reported long covid symptoms are; fatigue, shortness of breath, cough, joint pain, chest pain.
Virtual reality application provides its users with content created using computer technology. In a virtual environment with a high perception of reality, the aim is to enable mirror neuron activation, enabling the individual to interact with virtual objects and events with three-dimensional movements and to create the...
Virtual reality for training, treatment, rehabilitation, analysis and testing purposes in healthcare can be used. It is possible to use virtual reality for different purposes, for treatment and rehabilitation. With virtual reality applications in treatment and rehabilitation processes It was stated that patient motivat...
No study was found in the literature investigating the effect of virtual reality application on fatigue, functional capacity and respiratory function in long-term Covid-19 patients. The purpose of this study; To investigate the effect of virtual reality application on fatigue, functional level and respiratory function ...
<|newrecord|> nctId: NCT06374433 id: PREDICOM-01 briefTitle: Investigating the Plasticity of Human Predictive Coding Through Neuromodulation acronym: PREDICOM overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2026-12-31 date: 2024-04-18 date: 2024-04-18 name: Università Vita-Salute San Raffaele ...
<|newrecord|> nctId: NCT06374420 id: MD.21.11.564 briefTitle: Small Airway Disease And Bronchial Hyperreactivity In Patients With Post Acute Covid-19 Syndrome overallStatus: COMPLETED date: 2021-09-01 date: 2023-09-01 date: 2024-04-01 date: 2024-04-18 date: 2024-04-19 name: Mansoura University class: OTHER briefSummary...
<|newrecord|> nctId: NCT06374407 id: GT-001 briefTitle: The MIND-GUT Digital Pilot Intervention Study acronym: MINDGUT overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-05 date: 2026-12 date: 2024-04-18 date: 2024-04-18 name: University of Skövde class: OTHER name: State University of New York - Downstate Medi...
<|newrecord|> nctId: NCT06374394 id: 217848 id: 2023-510196-59-00 type: OTHER domain: EU CTR Number briefTitle: A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a COVID-19 mRNA Vaccine in Adults Aged 50 Years and Above overallStatus: NOT...
<|newrecord|> nctId: NCT06374381 id: 854990 briefTitle: PEACE for ImPACT Study overallStatus: ENROLLING_BY_INVITATION date: 2023-12-01 date: 2027-11 date: 2027-11 date: 2024-04-18 date: 2024-04-18 name: University of Pennsylvania class: OTHER name: Institute of Education Sciences name: Michigan State University briefSu...
<|newrecord|> nctId: NCT06374368 id: JID-SURG briefTitle: Small Bowel Diversion overallStatus: ACTIVE_NOT_RECRUITING date: 2019-05-01 date: 2024-12-31 date: 2024-12-31 date: 2024-04-18 date: 2024-04-24 name: University of Ostrava class: OTHER name: Institute for Clinical and Experimental Medicine name: Vitkovice Hospit...
<|newrecord|> nctId: NCT06374355 id: Semibranch_Retro briefTitle: Semibranch Registry - Retrospective overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-04 date: 2030-10 date: 2024-04-18 date: 2024-04-22 name: University Hospital Muenster class: OTHER briefSummary: The goal of this registry is to evaluate the s...
<|newrecord|> nctId: NCT06374342 id: SO01-TK-SUBSTITUTES briefTitle: BONE SUBSTITUTES OUTCOMES overallStatus: RECRUITING date: 2021-09-16 date: 2026-09-16 date: 2032-09-30 date: 2024-04-18 date: 2024-04-18 name: Teknimed class: INDUSTRY briefSummary: A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical dat...
TEKNIMED bone substitutes are legacy products, some marketed for more than 20 years. Their performance and safety have already been demonstrated by Post-Market Surveillance and previous clinical studies. The current Post-Market Clinical Follow-Up study aims to confirm these claims by collecting data in a "real-life" se...
The study is a retrospective and prospective global, single arm, non-controlled, multicentric, prospective observational study. Patients will be followed as per local standard medical care of the sites. conditions: Bone Resorption studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 425 typ...
<|newrecord|> nctId: NCT06374329 id: S68717 briefTitle: Effect of Interceptive Strategies on the Clinical Outcome of Impacted Maxillary Permanent Canines acronym: RCTcanines2 overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2026-08-01 date: 2027-08-01 date: 2024-04-18 date: 2024-04-24 name: Universitaire Zieken...
This study corresponds to the second phase of an RCT, based on the results of the first phase, published in July 2023 (S59030) (Willems G, Butaye C, Raes M, Zong C, Begnoni G, Cadenas de Llano-Pérula M. Early prevention of maxillary canine impaction: a randomized clinical trial. Eur J Orthod. 31;45(4):359-369). The fir...
<|newrecord|> nctId: NCT06374316 id: 2302888 briefTitle: Air Purifiers in Classrooms for Infection Control - a Pilot Study overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-15 date: 2024-05-01 date: 2024-05-01 date: 2024-04-18 date: 2024-04-18 name: Norwegian Institute of Public Health class: OTHER_GOV name: SINTEF He...
For this arm, we will randomize the three classrooms to each of three weekly programs for the air purifiers;
Program 1) Week 1, 4, and 7: Ceiling-mounted ON, Week 2, 5, and 8: No purifier on, Week 3, 6, and 9: Portable ON. Program 2) Week 1, 4, and 7: Portable ON, Week 2, 5, and 8: Ceiling-mounted ON, Week 3, 6, and 9: No purifier on. Program 3) Week 1, 4, and 7: No purifier on Week 2, 5, and 8: Portable ON, Week 3, 6, and 9:...
Each classroom will be assigned a computer-generated random number and will based on the ascending order of the random numbers be allocated to the three predetermined sequences of programs. primaryPurpose: OTHER masking: NONE count: 6 type: ACTUAL name: Ceiling-Mounted Air Purifiers name: Portable Air Purifiers name: P...
<|newrecord|> nctId: NCT06374303 id: CHRBSS 00001940 briefTitle: Novel Intervention to Improve Food Insecurity Among Individuals With Opioid Use Disorder: A Randomized Clinical Trial overallStatus: COMPLETED date: 2022-04-19 date: 2023-11-20 date: 2023-11-20 date: 2024-04-18 date: 2024-04-18 name: University of Vermont...
In this randomized pilot study, we evaluated a novel, mail-based meal delivery intervention for improving household FI and other outcomes among individuals receiving methadone or buprenorphine maintenance for OUD.
Fifty adults with FI and OUD were randomized to one of two 12-week experimental conditions: Nutritional Education (NE) participants received brief education, a list of FI-related resources in their community, and assistance with contacting those resources. NE + Meal Delivery (NE+MD) participants received the same educa...
The primary outcome of household FI was measured at monthly assessments using the USDA Household Food Security Survey. Secondary measures included depression symptoms (Beck Depression Inventory), quality of life (RAND-36 Quality of Life Survey), and drug use as measured by biochemical urinalysis.
The NE+MD intervention was associated with significant improvements in household FI, with fewer NE+MD participants meeting criteria for FI vs. NE participants at all three assessment timepoints (p's\<.05). Retention rates were similar between the two groups (88% and 84% for NE+MD and NE conditions, respectively; p=.68)...
Changes in FI status were also associated with improvements in other areas of functioning. NE+MD participants experienced reductions in depression symptomatology, with Beck Depression Inventory scores lower than intake at Weeks 4 and 8 (p's\<.05) and no changes among NE participants. NE+MD participants also experienced...
This study represents the first effort to develop and evaluate a novel intervention to reduce FI and related problems among individuals with OUD. These pilot data support the feasibility, acceptability and initial efficacy of the NE+MD intervention for improving household FI, as well as provide exciting new preliminary...
<|newrecord|> nctId: NCT06374290 id: HSC-MS-24-0024 briefTitle: Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-02-15 date: 2025-04-15 date: 2024-04-18 date: 2024-04-18 name: The University of Texas Health Science...
<|newrecord|> nctId: NCT06374277 id: 23-09339-IAA briefTitle: Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence acronym: MedAAAction overallStatus: RECRUITING date: 2024-04-06 date: 2027-09-30 date: 2028-01-31 date: 2024-04-18 date: 2024-04-25 name: University of Tennessee class: OTHER name:...
<|newrecord|> nctId: NCT06374264 id: NM100 briefTitle: Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder acronym: aNiMatO overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2024-12-31 date: 2024-12-31 date: 2024-04-18 date: 2024-04-24 name: MedRhythms, Inc. class: INDUSTR...
<|newrecord|> nctId: NCT06374251 id: 0S-23-2 id: NCI-2023-08890 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 0S-23-2 type: OTHER domain: USC / Norris Comprehensive Cancer Center id: P30CA014089 type: NIH link: https://reporter.nih.gov/quickSearch/P30CA014089 briefTitle: Narrative Medicine for Impr...
<|newrecord|> nctId: NCT06374238 id: UG3HL165839 type: NIH link: https://reporter.nih.gov/quickSearch/UG3HL165839 id: UG3HL165839 type: NIH link: https://reporter.nih.gov/quickSearch/UG3HL165839 briefTitle: Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain acronym: PRESENCE overallStatus: NOT_YET_R...
By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable...
<|newrecord|> nctId: NCT06374225 id: 23-0866 briefTitle: Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration Intervention acronym: SAVE-O2 AI overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-12-31 date: 2026-05-01 date: 2024-04-18 date: 2024-04-18 name: University of Colorado, Denver class...
<|newrecord|> nctId: NCT06374212 id: 24-0191 briefTitle: Anifrolumab for Hidradenitis Suppurativa overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-06 date: 2026-12 date: 2024-04-18 date: 2024-04-18 name: University of North Carolina, Chapel Hill class: OTHER name: AstraZeneca briefSummary: This clinical trial...