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* Aim 1:examine whether gamified ABM leads to greater change in the primary and secondary outcomes than sham ABM |
* Aim 1: establish that gamified ABM is at least as effective as traditional ABM. |
* Aim 2: identify moderators of ABM efficacy and mechanisms responsible for its efficacy. |
* Aim 3: Identify the durability of ABM on depression symptoms during short-term follow-up |
Participants will complete self-report questionnaires, complete eye-tracking tasks, and be clinically assessed through interviews by clinician researchers. |
If there is a comparison group: Researchers will compare sham, traditional, and gamified treatment groups to see if they moderate symptoms of depression. conditions: Depression studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE ... |
<|newrecord|> nctId: NCT06361082 id: CORPG5N0061 briefTitle: Ultrasonic Backscatter Imaging for ACL Reconstruction and Shoulder Diseases overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-10 date: 2025-10 date: 2024-04-11 date: 2024-04-11 name: Chang Gung Memorial Hospital class: OTHER briefSummary: This study ... |
ACL reconstruction is commonly performed, with postoperative complications including joint stiffness and muscle strength decline, associated with changes in muscle quality and volume. Similarly, soft tissue injuries around the shoulder and ankle are prevalent in sports medicine, with ultrasound used to assess the sever... |
The results of this project could significantly improve the diagnostic efficacy of musculoskeletal ultrasound, facilitating earlier treatment and reducing the socio-economic impacts. Academically, it positions the investigating team as pioneers in the application of ultrasound inverse scattering imaging technology. con... |
<|newrecord|> nctId: NCT06361069 id: aslıakdeniz briefTitle: Reducing Anxiety in Children Undergoing Day Surgery overallStatus: COMPLETED date: 2023-04-01 date: 2023-08-01 date: 2024-01-01 date: 2024-04-11 date: 2024-04-11 name: Bilecik Seyh Edebali Universitesi class: OTHER briefSummary: Aim: This study was conducted ... |
Methods: The study was conducted using the "pre-post test unmatched group model", one of the quasi-experimental methods. The study was conducted between April 2023 and January 2024 with children aged 6-12 years who were admitted to the pediatric clinic of a hospital for day surgery. A total of 85 children (including 20... |
<|newrecord|> nctId: NCT06361056 id: LCCC2140 briefTitle: Mobile Health App to Promote Participation of Black Women in Breast Cancer Clinical Trials overallStatus: RECRUITING date: 2022-05-02 date: 2025-01 date: 2026-01 date: 2024-04-11 date: 2024-04-17 name: UNC Lineberger Comprehensive Cancer Center class: OTHER brie... |
The "mHealth app" which can be used as a platform to share clinical trial education and communication, was created and tested in previous steps of this study. conditions: Breast Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: HEALTH_SERVICES_RESEARCH masking: N... |
<|newrecord|> nctId: NCT06361043 id: 2023-01833 briefTitle: Conebeam CT-based Online Adaptive Radio-Therapy for Esophageal Cancer (ARTEC) acronym: ARTEC overallStatus: RECRUITING date: 2024-04-20 date: 2027-02-28 date: 2027-02-28 date: 2024-04-11 date: 2024-04-25 name: Insel Gruppe AG, University Hospital Bern class: O... |
<|newrecord|> nctId: NCT06361030 id: HMPL-012-C2-PC01 briefTitle: Surufatinib Combined With Gemcitabine Plus Nab-paclitaxel in Locally Advanced Pancreatic Cancer overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-06-01 date: 2027-06-01 date: 2024-04-11 date: 2024-04-11 name: Wuhan Union Hospital, China class... |
<|newrecord|> nctId: NCT06361017 id: QNPY2022007 briefTitle: The Prediction of Hemorrhage Transformation by Cerebral Autoregulation in AIS Patient After Endovascular Thrombectomy acronym: PHASE overallStatus: ENROLLING_BY_INVITATION date: 2022-03-01 date: 2025-03-01 date: 2026-03-01 date: 2024-04-11 date: 2024-04-11 na... |
Patients: patients with AIS caused by middle cerebral artery or internal carotid artery occlusion who accepted EVT. |
dCA Examination: dCA examinations were performed at 24 hours, 48 hours, 72 hours, and 5 days after EVT. |
The objectives of the study were as follows: The changes of cerebral hemodynamics and parameters of dCA in different time periods after EVT were analyzed. So as to determine the correlation between hemodynamics and dCA change and HT and clinical outcome after EVT and to explore the predictors of HT and adverse clinical... |
<|newrecord|> nctId: NCT06361004 id: DBS for TR-TS briefTitle: Exploring DBS Efficacy in Treatment-refractory Tourette's Syndrome overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2028-12-31 date: 2029-12-31 date: 2024-04-11 date: 2024-04-11 name: Xuanwu Hospital, Beijing class: OTHER briefSummary: The primary p... |
<|newrecord|> nctId: NCT06360991 id: DBS for TR-OCD briefTitle: DBS for Treatment-resistant Obsessive-compulsive Disorder overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2028-12-31 date: 2029-12-31 date: 2024-04-11 date: 2024-04-11 name: Xuanwu Hospital, Beijing class: OTHER briefSummary: The primary purpose o... |
<|newrecord|> nctId: NCT06360978 id: docetaxel as a radiosenstizer briefTitle: Efficacy and Toxicity of Docetaxel as a Radiosenstizer in Head and Neck Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-06 date: 2027-06 date: 2024-04-11 date: 2024-04-11 name: Assiut University class: OTHER briefSummary: H... |
Approximately 90% of HNCs are squamous cell carcinoma . The major risk factors of head and neck squamous cell carcinoma (HNSCC) are tobacco and heavy alcohol use and human papillomavirus infection . There has been a significant decline in smoking in high-income countries during the last few decades, which has led to a ... |
Chemoradiation is one of the treatment options for locally advanced head and neck cancers, the drug of choice for radiosensitization is cisplatin Although cisplatin-based chemoradiotherapy (CRT) is the standard of care for locally advanced head and neck squamous cell carcinoma (LAHNSCC), cisplatin is contraindicated in... |
The addition of docetaxel to radiation improved DFS and OS in cisplatin-ineligible patients with LAHNSCC. conditions: Head and Neck Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 30 type: ESTIMATED name: Docetaxel measure: pr... |
<|newrecord|> nctId: NCT06360965 id: Shoufa2024-3-7045 briefTitle: Clinical Trial of Acupoint Application in Improving the Sequelae of Pelvic Inflammatory Disease and Chronic Pelvic Pain overallStatus: RECRUITING date: 2024-01-01 date: 2026-03-31 date: 2026-12-31 date: 2024-04-11 date: 2024-04-11 name: Beijing Hospital... |
<|newrecord|> nctId: NCT06360952 id: T23-03 briefTitle: A Comparator Study of a Tasso Device Blood Sample to Traditional Venous Blood Sample for CBC overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2024-07-30 date: 2024-07-30 date: 2024-04-11 date: 2024-04-26 name: Tasso Inc. class: INDUSTRY name: The Leukemia ... |
This investigation will include a minimum of 40 sample sets from unique patients. conditions: Leukopenia conditions: Leukocytosis conditions: Neutropenia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: Tasso+ CBC measure: Agreement between capillary and v... |
<|newrecord|> nctId: NCT06360939 id: ETH02659 briefTitle: Radiotherapy vs Catheter Ablation for Ventricular Tachycardia in Structural Heart Disease acronym: Radioablate overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2026-04-15 date: 2027-04-15 date: 2024-04-11 date: 2024-04-11 name: Western Sydney Local Healt... |
* What is the efficacy of SBRT compared to catheter ablation (CA) in achieving a ≥ 75% reduction in VT burden at 6 months |
* What is the comparable safety profile of SBRT vs CA Researchers will compare SBRT and CA (standard of care). conditions: Ventricular Tachycardia conditions: Cardiomyopathies conditions: Arrhythmias, Cardiac conditions: Ventricular Arrythmia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel... |
<|newrecord|> nctId: NCT06360926 id: 2024-A00526-41 briefTitle: Improvement Image Quality for SuperSonic® MACH Ultrasound System acronym: MACH IQ overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-11 date: 2024-04-11 name: SuperSonic Imagine class: INDUSTRY briefSummary: The aim o... |
<|newrecord|> nctId: NCT06360913 id: 2023/09AOU/346 briefTitle: Blood Spot and Urine Metabolomic Screening Applied to Rare Diseases acronym: BUSARD overallStatus: RECRUITING date: 2024-01-03 date: 2028-01 date: 2028-01 date: 2024-04-11 date: 2024-04-12 name: Cliniques universitaires Saint-Luc- Université Catholique de ... |
A metabolomic database using a high-resolution mass spectrometer (i.e. the "Device") will be generated and specific biomarkers for the diseases will be confirmed or uncovered. The ultimate goal is to facilitate and improve the diagnosis and screening of the patients affected by these disorders, but also to improve the ... |
High-resolution mass spectrometry allows the measurement of thousands of metabolites in a single analysis. The current biochemical tests used for the diagnosis of hereditary metabolic diseases are only using a combination of maximum a few dozens of biomarkers in one analysis. |
Objectives Unravel new biomarkers for diagnosis (+/- explore the altered pathways...) Uncover and/or validate newborn screening biomarkers through retrospective analysis of preserved newborn DBS from confirmed patients (useful for first or second tier biochemical NBS testing!) Validation of LC-MS qTOF for metabolomics ... |
1. Control subjects |
2. Confirmed patients (rare diseases) |
3. Suspected patients (rare diseases) primaryPurpose: DIAGNOSTIC masking: NONE count: 2286 type: ESTIMATED name: High resolution mass spectrometry measure: Uncover new biomarkers in dried blood spots and urines samples able to improve the diagnosis of rare diseases sex: ALL minimumAge: 1 Day maximumAge: 99 Years stdAge... |
<|newrecord|> nctId: NCT06360900 id: 2024P000849 briefTitle: Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Cognitive Behavioral Therapy in Functional Dyspepsia overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2029-03 date: 2029-03 date: 2024-04-11 date: 2024-04-11 name: Spaulding Rehabilitation H... |
<|newrecord|> nctId: NCT06360887 id: DRKS00030614 briefTitle: Management of Proximal Humerus Fractures in Adults: a Clinical Trial overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-01-31 date: 2028-01-31 date: 2024-04-11 date: 2024-04-12 name: Regional Hospital of Bolzano class: OTHER briefSummary: Prospective... |
<|newrecord|> nctId: NCT06360874 id: ND003-I-06 briefTitle: A Study to Evaluate Safety, Tolerability and Pharmacokinetic of ND-003 Tablets in Healthy Adults overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2025-02 date: 2024-04-11 date: 2024-04-11 name: Shenzhen NewDEL Biotech, Co., Ltd class: INDUST... |
<|newrecord|> nctId: NCT06360861 id: 1400-1-233-51589 id: IR.TUMS.MEDICINE.REC.1400.197 type: OTHER_GRANT domain: Tehran University of Medical Sciences briefTitle: Evaluate the Safety and Feasibility of Allogeneic Mesenchymal Stem Cells in Patients With Multiple Sclerosis acronym: MS overallStatus: COMPLETED date: 2019... |
Monitoring will be encompassed baseline assessments and follow-ups over subsequent months, evaluating clinical signs, Expanded Disability Status Scale (EDSS), cytokines, diffusion tensor imaging (DTI), functional MRI (fMRI), cognitive \& psychological evaluations, and flow cytometry for B cell markers. conditions: Mult... |
<|newrecord|> nctId: NCT06360848 id: IRB00001192 briefTitle: Surgical Treamtment of Pseudarthrosis of the Humerus (Study of a Series of 53 Cases) overallStatus: COMPLETED date: 2005-01-01 date: 2021-01-01 date: 2021-01-01 date: 2024-04-11 date: 2024-04-11 name: Ibn Jazzar Hospital class: OTHER briefSummary: Pseudarthro... |
The aim of our work is to evaluate the anatomical and functional results of different surgical techniques. used. conditions: Humerus Fracture studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 53 type: ACTUAL name: surgery measure: Distribution of atrophic pseudarthrosis according... |
<|newrecord|> nctId: NCT06360835 id: IRB00001193 briefTitle: Our Experience in the Management of Therapeutic Failures of Fractures of the Proximal End of the Femur (About 35 Cases) overallStatus: COMPLETED date: 2015-01-01 date: 2021-12-01 date: 2021-12-02 date: 2024-04-11 date: 2024-04-11 name: Ibn Jazzar Hospital cla... |
Osteosynthesis alters the mechanical dynamics of the bone segment, which undergoes continual changes during the consolidation and mobilization phases of recovery. Throughout these stages, a range of mechanical complications may arise, posing challenges despite the successful prevention of infections. Non-infectious com... |
In light of these considerations, surgeons must exercise meticulous care in selecting synthetic materials to mitigate the risk of osteosynthesis failures. In cases where internal fixation fails, the standard recourse often involves converting to total hip arthroplasty (THA). |
However, it is essential to note that THA subsequent to complications arising from proximal femur osteosynthesis presents a higher incidence of both intraoperative and postoperative complications compared to the implantation of primary total hip prostheses. Thus, while osteosynthesis remains a valuable intervention for... |
<|newrecord|> nctId: NCT06360822 id: 19317 briefTitle: Increasing Equity in Lung Cancer Screening acronym: LUCARE overallStatus: RECRUITING date: 2023-12-01 date: 2027-02-01 date: 2027-02-01 date: 2024-04-11 date: 2024-04-11 name: Indiana University class: OTHER name: Eskenazi Health briefSummary: The overall objective... |
<|newrecord|> nctId: NCT06360809 id: 2024 PARINEFC 00001 briefTitle: Prehabilitation Exercise Program in Breast Cancer: Effects on Quality of Life and Tumor Microenvironment (PEP_BC) acronym: PEP_BC overallStatus: RECRUITING date: 2024-03-22 date: 2025-06 date: 2025-06 date: 2024-04-11 date: 2024-04-11 name: Institut N... |
This study aims to provide valuable insights into the potential benefits of PE for BC patients and its impact on the tumor microenvironment. The hypothesis is that PE in BC patients will improve their quality of life, reduce fatigue, increase muscle mass, decrease fat mass, and enhance physical fitness. Additionally, b... |
The study will include 76 participants aged 18-65 years, meeting specific criteria such as a diagnosis of hormone receptor-positive BC, no medical contraindications for exercise, no metastatic cancer, and no structured exercise in the last six months. These participants will be randomly assigned to a PE group or a cont... |
<|newrecord|> nctId: NCT06360796 id: 2023-ADC189-I-010 briefTitle: Study of Pharmacokinetics and Metabolism on [(14)C]ADC189 overallStatus: RECRUITING date: 2023-11-24 date: 2024-06-30 date: 2024-07-30 date: 2024-04-11 date: 2024-04-11 name: Jiaxing AnDiCon Biotech Co.,Ltd class: INDUSTRY briefSummary: This study is de... |
<|newrecord|> nctId: NCT06360783 id: Pro00111388 briefTitle: COVID-19 Quick Start - Test and Treat in Africa overallStatus: ACTIVE_NOT_RECRUITING date: 2023-02-01 date: 2024-06 date: 2024-06 date: 2024-04-11 date: 2024-04-26 name: Duke University class: OTHER name: Duke Clinical Research Institute name: Clinton Health ... |
<|newrecord|> nctId: NCT06360770 id: NIRSCovidSBCelje briefTitle: Assessement of Microcirculation With NIRS Predicts Sepsis Development in Patients With Severe Covid-19 Pneumonia overallStatus: COMPLETED date: 2021-12-01 date: 2023-02-28 date: 2023-04-30 date: 2024-04-11 date: 2024-04-12 name: General and Teaching Hosp... |
<|newrecord|> nctId: NCT06360757 id: DHF-21-2141-1 briefTitle: Clinical Evaluation of the NeuMoDx SARS-CoV-2 Assay (COVID-19) overallStatus: RECRUITING date: 2024-02-06 date: 2024-09-01 date: 2024-09-01 date: 2024-04-11 date: 2024-04-11 name: QIAGEN Gaithersburg, Inc class: INDUSTRY briefSummary: A multicenter study, u... |
<|newrecord|> nctId: NCT06360744 id: ENFORCE PLUS briefTitle: A Phase IV Vaccine Study Under the National Cohort Study of Effectiveness and Safety of SARS-CoV-2 (COVID-19) Vaccines. overallStatus: COMPLETED date: 2021-07-05 date: 2023-12-31 date: 2023-12-31 date: 2024-04-11 date: 2024-04-11 name: Jens D Lundgren, MD cl... |
The Danish Medicines Agency has approved the vaccine from J\&J for use in Denmark, however it is not currently part of the national vaccine programme. |
The design is an open-labelled, non-randomised, parallel group, phase IV study with historical controls. A sub-study will be embedded within this master protocol addressing basic and translational research questions requiring additional sampling of biological material (under separate participant informed consent). cond... |
<|newrecord|> nctId: NCT06360731 id: 1018 briefTitle: The Effect of 4-7-8 Breathing Exercise Technique on Tinnitus overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-18 date: 2024-05-31 date: 2024-05-31 date: 2024-04-11 date: 2024-04-23 name: Ege University class: OTHER briefSummary: The goal of this study is to evalua... |
There will be a parallel-group randomized controlled trial study and consists of two groups. |
Both groups will receive 1 hour of informative session on tinnitus and the experimental group will also perform 4-7-8 breathing exercises for 6 weeks. Visual analog scale, tinnitus handicap inventory, insomnia severity index, trait anxiety inventory, and perceived stress scale will be applied before and after the appli... |
<|newrecord|> nctId: NCT06360718 id: CHLA-23-00170 briefTitle: Effects of Using a Storybook, to Explain Leukemia to Children Versus the Standard Child Life Intervention, on Parental Stress. overallStatus: RECRUITING date: 2024-02-03 date: 2025-05-15 date: 2025-05-15 date: 2024-04-11 date: 2024-04-19 name: Children's Ho... |
The main questions it aims to answer are: |
* What effect will the storybook have on parent/legal guardian stress at three timepoints: baseline, discharge, and follow up? |
* Will this storybook impact parent/legal guardian comfort levels and improve their child's understanding? |
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