harpreetmann/entity_extraction_ade · Datasets at Hugging Face

text stringlengths 22 455	pairs listlengths 1 24
A 58-year old patient is reported who developed an ischaemic cerebrovascular accident 22 hours after successful thrombolysis with streptokinase for life-threatening pulmonary emboli.	[ [ "streptokinase", "ischaemic cerebrovascular accident" ] ]
We report the cases of two patients who developed acute hepatitis after taking riluzole at the recommended dose (100 mg daily) for 7 and 4 weeks, respectively.	[ [ "riluzole", "hepatitis" ] ]
In eight patients, a mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L was observed after a single 200 mg intravenous dose of lorcainide.	[ [ "lorcainide", "decrease in serum Na+" ] ]
A depressed woman with no history of bipolar illness developed a manic episode during treatment with fluoxetine.	[ [ "fluoxetine", "manic episode" ] ]
Three patients received respectively 190 mg, 175 mg, and 196 mg of methotrexate and developed bilateral pulmonary infiltrates without evidence of peripheral blood eosinophilia.	[ [ "methotrexate", "bilateral pulmonary infiltrates" ] ]
We describe a 5-year-old girl showed recovery of vincristine induced cranial polyneuropathy with pyridoxine and pyridostigmine treatment.	[ [ "vincristine", "cranial polyneuropathy" ] ]
RESULTS: Five of 70 patients who had begun leflunomide therapy had significant weight loss that could not be linked to other identifiable etiologies.	[ [ "leflunomide", "weight loss" ] ]
Argatroban for heparin-induced thrombocytopenia in hepato-renal failure and CVVHD.	[ [ "heparin", "thrombocytopenia" ] ]
Renal injury due to anastrozole has not been published in the English literature.	[ [ "anastrozole", "Renal injury" ] ]
Pulmonary toxicity with mefloquine.	[ [ "mefloquine", "Pulmonary toxicity" ] ]
A patient, while on intravenous ritodrine therapy for preterm labor, experienced an episode of acute chest pain.	[ [ "ritodrine", "acute chest pain" ] ]
Recurrent hyponatremia associated with citalopram and mirtazapine.	[ [ "mirtazapine", "Recurrent hyponatremia" ], [ "citalopram", "Recurrent hyponatremia" ] ]
This report describes an unexpected drug-induced hepatitis in a previously healthy young woman exposed to 2 doses of amodiaquine and artesunate.	[ [ "artesunate", "hepatitis" ], [ "amodiaquine", "hepatitis" ] ]
This report presents a case of acute lung injury developing within hours after administration of mefloquine for a low-level Plasmodium falciparum malaria, which was persistent despite halofantrine therapy.	[ [ "mefloquine", "acute lung injury" ] ]
CONCLUSION: This case illustrates a potential link between dermatologic and ocular 5-FU toxicities.	[ [ "5-FU", "dermatologic and ocular 5-FU toxicities" ] ]
In four patients, spasm occurred spontaneous and in one patient after 0.05 mg of ergonovine.	[ [ "ergonovine", "spasm" ] ]
A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%.	[ [ "betamethasone valerate", "postprandial hyperglycemia" ] ]
One of these was clofazimine, an aniline aposafranine derivative known to produce a ceroid-like pigment in the tissues of patients treated with this drug or lepromatous leprosy.	[ [ "clofazimine", "ceroid-like pigment" ] ]
CONCLUSIONS: Hypersensitivity reactions to cyclosporine are due to Cremophor EL.	[ [ "cyclosporine", "Hypersensitivity reactions" ], [ "Cremophor EL", "Hypersensitivity reactions" ] ]
A generalized tonic-clonic seizure occurred a few minutes after injection of the morphine antagonist naloxone.	[ [ "naloxone", "generalized tonic-clonic seizure" ] ]
The majority of radiation recall reactions attributed to gemcitabine are reported to affect internal tissue or organs.	[ [ "gemcitabine", "radiation recall reactions" ] ]
Intrahepatic cholestasis and cutaneous bullae associated with glibenclamide therapy are described in a 61-year-old diabetic patient who presented wit hypoglycaemic coma.	[ [ "glibenclamide", "Intrahepatic cholestasis" ], [ "glibenclamide", "cutaneous bullae" ] ]
This concerns 2 male patients who experienced incontinence while taking venlafaxine.	[ [ "venlafaxine", "incontinence" ] ]
Total blindness with a transient tonic pupillary response, denervation supersensitivity, and abnormal visual-evoked potentials developed in a 54-year-old man after the use of quinine sulfate for leg cramps.	[ [ "quinine sulfate", "Total blindness with a transient tonic pupillary response" ], [ "quinine sulfate", "denervation supersensitivity" ], [ "quinine sulfate", "abnormal visual-evoked potentials" ] ]
Pigmentary disorders are recognized adverse effects of the semi-synthetic tetracycline derivative antibiotic, minocycline.	[ [ "minocycline", "Pigmentary disorders" ] ]
Ticlopidine-induced marrow aplasia treated with cyclosporine.	[ [ "Ticlopidine", "marrow aplasia" ] ]
Postoperative hypocalcemic tetany caused by fleet phospho-soda preparation in a patient taking alendronate sodium: report of a case.	[ [ "fleet phospho-soda", "hypocalcemic tetany" ], [ "alendronate sodium", "hypocalcemic tetany" ] ]
Cryptococcus neoformans fatal sepsis in a chronic lymphocytic leukemia patient treated with alemtuzumab: case report and review of the literature.	[ [ "alemtuzumab", "Cryptococcus neoformans fatal sepsis" ] ]
Cough induced by quinapril with resolution after changing to fosinopril.	[ [ "quinapril", "Cough" ] ]
Neurophysiological mechanisms which aid in elucidating the role of disulfiram in the etiology of catatonia are discussed.	[ [ "disulfiram", "catatonia" ] ]
Fracture of the femoral neck occurred in one patient during PSL therapy, although the relationship between the fracture and PSL therapy was uncertain.	[ [ "PSL", "Fracture of the femoral neck" ] ]
Visual loss after a single small dose of vincristine has never been reported.	[ [ "vincristine", "Visual loss" ] ]
Massive CBZ OD may produce a reversible encephalopathy that includes cortical hyperexcitability, a profound burst-suppression EEG pattern, and cranial nerve areflexia.	[ [ "CBZ", "cranial nerve areflexia" ], [ "CBZ", "cortical hyperexcitability" ], [ "CBZ", "profound burst-suppression EEG pattern" ], [ "CBZ", "reversible encephalopathy" ] ]
When measured, the serum lithium level had increased 4-fold during acyclovir therapy.	[ [ "acyclovir", "serum lithium level had increased" ], [ "lithium", "serum lithium level had increased" ] ]
Ezetimibe-induced acute pancreatitis.	[ [ "Ezetimibe", "acute pancreatitis" ] ]
The ulcer did not respond to antibiotic treatment and healed shortly after withholding ATRA.	[ [ "ATRA", "ulcer" ] ]
Multiple pulmonary nodules: an unusual presentation of fludarabine pulmonary toxicity: case report and review of literature.	[ [ "fludarabine", "pulmonary toxicity" ], [ "fludarabine", "Multiple pulmonary nodules" ] ]
Fulminant hepatic failure associated with bicalutamide.	[ [ "bicalutamide", "Fulminant hepatic failure" ] ]
These in vitro findings and clinical course suggest that TRAb/TBII without thyroid-stimulating activity may develop in patients with amiodarone-induced destructive thyroiditis, as reported in patients with destructive thyroiditis, such as subacute and silent thyroiditis.	[ [ "amiodarone", "TRAb/TBII without thyroid-stimulating activity" ], [ "amiodarone", "thyroiditis" ], [ "amiodarone", "destructive thyroiditis" ] ]
The newborn manifested a four day course of lethargy with unexplained high lithium levels in the adult toxic range.	[ [ "lithium", "lethargy" ] ]
Spindle coma in benzodiazepine toxicity: case report.	[ [ "benzodiazepine", "Spindle coma" ] ]
Sudden cardiac death due to hypersensitivity myocarditis during clozapine treatment.	[ [ "clozapine", "Sudden cardiac death" ], [ "clozapine", "hypersensitivity myocarditis" ] ]
PATIENT AND METHOD: A 34-year-old woman with chronic hepatitis C, genotype 3, receiving pegylated interferon alpha-2a and ribavirin for 6 months, developed progressive malaise and anemia 6 months after the end of treatment.	[ [ "ribavirin", "anemia" ], [ "pegylated interferon alpha-2a", "anemia" ], [ "pegylated interferon alpha-2a", "progressive malaise" ], [ "ribavirin", "progressive malaise" ] ]
Multiple myeloma complicated by congestive heart failure following first administration of recombinant alpha-interferon.	[ [ "recombinant alpha-interferon", "congestive heart failure" ] ]
However, a large case-control study included three cases of either Stevens-Johnson syndrome or toxic epidermal necrolysis associated with ofloxacin use, but no details of the cases were given.	[ [ "ofloxacin", "toxic epidermal necrolysis" ], [ "ofloxacin", "Stevens-Johnson syndrome" ] ]
Foscarnet-induced severe hypomagnesemia and other electrolyte disorders.	[ [ "Foscarnet", "electrolyte disorders" ], [ "Foscarnet", "severe hypomagnesemia" ] ]
Intravenous valproate associated with significant hypotension in the treatment of status epilepticus.	[ [ "valproate", "hypotension" ] ]
To our knowledge, this is the first case of spontaneous remission of MTX-associated gastric LPD after discontinuation of MTX therapy.	[ [ "MTX", "gastric LPD" ] ]
Ofloxacin: a probable cause of toxic epidermal necrolysis.	[ [ "Ofloxacin", "toxic epidermal necrolysis" ] ]
Trimethoprim-sulfamethoxazole-induced aseptic meningitis.	[ [ "Trimethoprim-sulfamethoxazole", "aseptic meningitis" ] ]
Hepatotoxicity induced by cyproterone acetate: a report of three cases.	[ [ "cyproterone acetate", "Hepatotoxicity" ] ]
Prolongation of the QT interval observed in a Japanese patient with vivax malaria following treatment with halofantrine.	[ [ "halofantrine", "Prolongation of the QT interval" ] ]
We report a case of radiotherapy-enhanced aminoglutethimide skin toxicity in a patient with metastatic breast cancer.	[ [ "aminoglutethimide", "skin toxicity" ] ]
Acute myocardial ischemia following accidental intravenous administration of epinephrine in high concentration.	[ [ "epinephrine", "Acute myocardial ischemia" ] ]
After nine previous uncomplicated cycles she developed severe anaphylaxis to cisplatin.	[ [ "cisplatin", "anaphylaxis" ] ]
A 16-year-old boy developed fever, generalized rigidity, leukocytosis, and increased serum transaminase and creatine kinase levels while receiving treatment with olanzapine and lithium.	[ [ "olanzapine", "generalized rigidity" ], [ "olanzapine", "leukocytosis" ], [ "olanzapine", "fever" ], [ "lithium", "fever" ], [ "lithium", "leukocytosis" ], [ "lithium", "increased serum transaminase and creatine kinase" ], [ "olanzapine",...
A case of phenobarbital exacerbation of a preexisting maladaptive behavior partially suppressed by chlorpromazine and misinterpreted as chlorpromazine efficacy.	[ [ "phenobarbital", "exacerbation of a preexisting maladaptive behavior" ] ]
Cardiac arrest after esmolol administration: a review of acute beta-blocker toxicity.	[ [ "esmolol", "Cardiac arrest" ] ]
Interference with the cortisol axis by the microtubule antagonist, CPH82.	[ [ "CPH82", "Interference with the cortisol axis" ] ]
A patient is described who developed a poorly differentiated sarcoma after cyclophosphamide was used to treat his rheumatoid arthritis.	[ [ "cyclophosphamide", "sarcoma" ] ]
Seventy-four per cent of patients with epileptogenic disorders seen at the Emergency Unit at Groote Schuur Hospital were on phenytoin and 11.6% of these had blood levels in the toxic range.	[ [ "phenytoin", "blood levels in the toxic range" ] ]
CONCLUSIONS: Peripheral administration of low-dose vasopressin for septic shock should be discouraged because of the risk of ischemic skin complications.	[ [ "vasopressin", "ischemic skin complications" ] ]
Transient global amnesia after clioquinol: five personal observations from outside Japan.	[ [ "clioquinol", "Transient global amnesia" ] ]
Withdrawal of Depakote resulted in resolution of the effusion.	[ [ "Depakote", "effusion" ] ]
Thoracoscopic biopsy to confirm metastasis revealed instead fibrotic lesions apparently attributable to bleomycin or cyclophosphamide.	[ [ "cyclophosphamide", "fibrotic lesions" ], [ "bleomycin", "fibrotic lesions" ] ]
We report the first case of acute renal failure with hyperkalemia associated with the recently marketed direct renin inhibitor aliskiren.	[ [ "aliskiren", "hyperkalemia" ], [ "aliskiren", "acute renal failure" ] ]
We describe two ELBW infants affected by hyperkalaemia, treated with Kayexalate, who developed serious hypernatraemia, that has never been reported before in preterm infants.	[ [ "Kayexalate", "hypernatraemia" ] ]
The mechanism of RTA induced by FK506 has not yet been clearly elucidated.	[ [ "FK506", "RTA" ] ]
We describe 2 cases of SJS related to nevirapine use and review the literature on this newly recognized association.	[ [ "nevirapine", "SJS" ] ]
Osteonecrosis is a serious side effect of antiemetic treatment with dexamethasone and this serious complication should be incorporated in the current guidelines.	[ [ "dexamethasone", "Osteonecrosis" ] ]
Adenosine-induced ventricular fibrillation.	[ [ "Adenosine", "ventricular fibrillation" ] ]
The cause of his bleeding was a severe thrombocytopoaenia, induced by chronic ingestion of quinine.	[ [ "quinine", "severe thrombocytopoaenia" ] ]
Horner's syndrome and demyelinating peripheral neuropathy caused by high-dose cytosine arabinoside.	[ [ "cytosine arabinoside", "demyelinating peripheral neuropathy" ], [ "cytosine arabinoside", "Horner's syndrome" ] ]
Carbamazepine-induced hyperammonemia.	[ [ "Carbamazepine", "hyperammonemia" ] ]
Corneal endothelial deposits associated with rifabutin use.	[ [ "rifabutin", "Corneal endothelial deposits" ] ]
CONCLUSIONS: There is very little published information regarding ofloxacin-induced toxic epidermal necrolysis.	[ [ "ofloxacin", "toxic epidermal necrolysis" ] ]
We report three cases of severe hepatotoxicity related to benzarone, a benzofuran derivative.	[ [ "benzarone", "severe hepatotoxicity" ] ]
The results clearly demonstrate that CPH82 was associated with suppression of the endogeneous production of ACTH and cortisol with a concomitant paradoxical picture of clinical hypercortisolism.	[ [ "CPH82", "hypercortisolism" ], [ "CPH82", "suppression of the endogeneous production of ACTH and cortisol" ] ]
Severe acidosis from acetazolamide in a diabetic patient.	[ [ "acetazolamide", "Severe acidosis" ] ]
Rupture of a cerebral aneurysm associated with nifedipine treatment.	[ [ "nifedipine", "Rupture of a cerebral aneurysm" ] ]
CONCLUSION: The findings in these two patients suggest that colchicine may delay corneal wound healing.	[ [ "colchicine", "delay corneal wound healing" ] ]
We describe a 74-year-old man with rheumatoid arthritis (RA) who developed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) 1.5 months after commencement of mizoribin prescription when his arthritis was improved.	[ [ "mizoribin", "syndrome of inappropriate secretion of antidiuretic hormone" ], [ "mizoribin", "SIADH" ] ]
Theoretical basal ganglia toxicologic mechanisms of methanol poisoning are reviewed, and the role of brain imaging studies will regard to diagnosis, prognosis and impact on management is discussed.	[ [ "methanol", "methanol poisoning" ] ]
We present a case report of a patient who developed a prolonged QT while being treated with oral methadone for a chronic pain syndrome.	[ [ "methadone", "prolonged QT" ] ]
We describe 2 children with cerebral palsy who suffered significant morbidity immediately after treatment with hyperbaric oxygen.	[ [ "hyperbaric oxygen", "morbidity" ] ]
We report on three observations of parkinsonian patients with levo-dopa-induced diphasic dyskinesias, who received subcutaneous apomorphine to reduce the duration of abnormal movements.	[ [ "levo-dopa", "diphasic dyskinesias" ] ]
BACKGROUND: Gemcitabine has mild renal toxicity, but cases of gemcitabine-associated hemolytic-uremic syndrome (HUS) have been reported.	[ [ "gemcitabine", "hemolytic-uremic syndrome" ], [ "Gemcitabine", "HUS" ], [ "gemcitabine", "HUS" ], [ "Gemcitabine", "renal toxicity" ], [ "Gemcitabine", "hemolytic-uremic syndrome" ] ]
A 59-year-old woman with myasthenia gravis who received a large dose of pyridostigmine bromide developed postoperative psychosis and was diagnosed as having bromide intoxication.	[ [ "pyridostigmine bromide", "bromide intoxication" ], [ "pyridostigmine bromide", "postoperative psychosis" ] ]
Capecitabine-induced headache responding to diltiazem.	[ [ "Capecitabine", "headache" ] ]
Acute non-lymphocytic leukemia in patients with ovarian carcinoma following long-term treatment with Treosulfan (= dihydroxybusulfan).	[ [ "Treosulfan", "Acute non-lymphocytic leukemia" ], [ "dihydroxybusulfan", "Acute non-lymphocytic leukemia" ] ]
Based on the Naranjo probability scale, serotonin syndrome was a probable adverse reaction associated with co-administration of citalopram and fentanyl.	[ [ "citalopram", "serotonin syndrome" ], [ "fentanyl", "serotonin syndrome" ] ]
The incidence of oral-verapamil-induced hypotension in the presence of concomitant beta-adrenergic blockade by the oral route is quite rare.	[ [ "verapamil", "hypotension" ] ]
Acute acoustic nerve palsy associated with vincristine therapy.	[ [ "vincristine", "Acute acoustic nerve palsy" ] ]
Disopyramide (Norpace)-induced hypoglycemia.	[ [ "Disopyramide", "hypoglycemia" ], [ "Norpace", "hypoglycemia" ] ]
We report 5 patients (3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated ...	[ [ "pegylated interferon alfa-2b", "local cutaneous reactions" ], [ "ribavirin", "local cutaneous reactions" ] ]
Capecitabine-induced multifocal leukoencephalopathy: a report of five cases.	[ [ "Capecitabine", "multifocal leukoencephalopathy" ] ]
This report highlights a case of drug-induced dysphagia in a patient receiving haloperidol for obsessive nocturnal thoughts and auditory disturbances.	[ [ "haloperidol", "dysphagia" ] ]
The currently available clinical and neuropharmacologic data suggest that carbamazepine may be an antagonist of dopamine and that this property is responsible for the production of dystonia.	[ [ "carbamazepine", "dystonia" ] ]
One patient had severe temporary weakness after an ampicillin sodium challenge.	[ [ "ampicillin sodium", "severe temporary weakness" ] ]
Effect of beta-blockade on symptomatic dexamethasone-induced hypertrophic obstructive cardiomyopathy in premature infants: three case reports and literature review.	[ [ "dexamethasone", "hypertrophic obstructive cardiomyopathy" ] ]

A 58-year old patient is reported who developed an ischaemic cerebrovascular accident 22 hours after successful thrombolysis with streptokinase for life-threatening pulmonary emboli.

[ [ "streptokinase", "ischaemic cerebrovascular accident" ] ]

We report the cases of two patients who developed acute hepatitis after taking riluzole at the recommended dose (100 mg daily) for 7 and 4 weeks, respectively.

[ [ "riluzole", "hepatitis" ] ]

In eight patients, a mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L was observed after a single 200 mg intravenous dose of lorcainide.

[ [ "lorcainide", "decrease in serum Na+" ] ]

A depressed woman with no history of bipolar illness developed a manic episode during treatment with fluoxetine.

[ [ "fluoxetine", "manic episode" ] ]

Three patients received respectively 190 mg, 175 mg, and 196 mg of methotrexate and developed bilateral pulmonary infiltrates without evidence of peripheral blood eosinophilia.

[ [ "methotrexate", "bilateral pulmonary infiltrates" ] ]

We describe a 5-year-old girl showed recovery of vincristine induced cranial polyneuropathy with pyridoxine and pyridostigmine treatment.

[ [ "vincristine", "cranial polyneuropathy" ] ]

RESULTS: Five of 70 patients who had begun leflunomide therapy had significant weight loss that could not be linked to other identifiable etiologies.

[ [ "leflunomide", "weight loss" ] ]

Argatroban for heparin-induced thrombocytopenia in hepato-renal failure and CVVHD.

[ [ "heparin", "thrombocytopenia" ] ]

Renal injury due to anastrozole has not been published in the English literature.

[ [ "anastrozole", "Renal injury" ] ]

Pulmonary toxicity with mefloquine.

[ [ "mefloquine", "Pulmonary toxicity" ] ]

A patient, while on intravenous ritodrine therapy for preterm labor, experienced an episode of acute chest pain.

[ [ "ritodrine", "acute chest pain" ] ]

Recurrent hyponatremia associated with citalopram and mirtazapine.

[ [ "mirtazapine", "Recurrent hyponatremia" ], [ "citalopram", "Recurrent hyponatremia" ] ]

This report describes an unexpected drug-induced hepatitis in a previously healthy young woman exposed to 2 doses of amodiaquine and artesunate.

[ [ "artesunate", "hepatitis" ], [ "amodiaquine", "hepatitis" ] ]

This report presents a case of acute lung injury developing within hours after administration of mefloquine for a low-level Plasmodium falciparum malaria, which was persistent despite halofantrine therapy.

[ [ "mefloquine", "acute lung injury" ] ]

CONCLUSION: This case illustrates a potential link between dermatologic and ocular 5-FU toxicities.

[ [ "5-FU", "dermatologic and ocular 5-FU toxicities" ] ]

In four patients, spasm occurred spontaneous and in one patient after 0.05 mg of ergonovine.

[ [ "ergonovine", "spasm" ] ]

A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%.

[ [ "betamethasone valerate", "postprandial hyperglycemia" ] ]

One of these was clofazimine, an aniline aposafranine derivative known to produce a ceroid-like pigment in the tissues of patients treated with this drug or lepromatous leprosy.

[ [ "clofazimine", "ceroid-like pigment" ] ]

CONCLUSIONS: Hypersensitivity reactions to cyclosporine are due to Cremophor EL.

[ [ "cyclosporine", "Hypersensitivity reactions" ], [ "Cremophor EL", "Hypersensitivity reactions" ] ]

A generalized tonic-clonic seizure occurred a few minutes after injection of the morphine antagonist naloxone.

[ [ "naloxone", "generalized tonic-clonic seizure" ] ]

The majority of radiation recall reactions attributed to gemcitabine are reported to affect internal tissue or organs.

[ [ "gemcitabine", "radiation recall reactions" ] ]

Intrahepatic cholestasis and cutaneous bullae associated with glibenclamide therapy are described in a 61-year-old diabetic patient who presented wit hypoglycaemic coma.

[ [ "glibenclamide", "Intrahepatic cholestasis" ], [ "glibenclamide", "cutaneous bullae" ] ]

This concerns 2 male patients who experienced incontinence while taking venlafaxine.

[ [ "venlafaxine", "incontinence" ] ]

Total blindness with a transient tonic pupillary response, denervation supersensitivity, and abnormal visual-evoked potentials developed in a 54-year-old man after the use of quinine sulfate for leg cramps.

[ [ "quinine sulfate", "Total blindness with a transient tonic pupillary response" ], [ "quinine sulfate", "denervation supersensitivity" ], [ "quinine sulfate", "abnormal visual-evoked potentials" ] ]

Pigmentary disorders are recognized adverse effects of the semi-synthetic tetracycline derivative antibiotic, minocycline.

[ [ "minocycline", "Pigmentary disorders" ] ]

Ticlopidine-induced marrow aplasia treated with cyclosporine.

[ [ "Ticlopidine", "marrow aplasia" ] ]

Postoperative hypocalcemic tetany caused by fleet phospho-soda preparation in a patient taking alendronate sodium: report of a case.

[ [ "fleet phospho-soda", "hypocalcemic tetany" ], [ "alendronate sodium", "hypocalcemic tetany" ] ]

Cryptococcus neoformans fatal sepsis in a chronic lymphocytic leukemia patient treated with alemtuzumab: case report and review of the literature.

[ [ "alemtuzumab", "Cryptococcus neoformans fatal sepsis" ] ]

Cough induced by quinapril with resolution after changing to fosinopril.

[ [ "quinapril", "Cough" ] ]

Neurophysiological mechanisms which aid in elucidating the role of disulfiram in the etiology of catatonia are discussed.

[ [ "disulfiram", "catatonia" ] ]

Fracture of the femoral neck occurred in one patient during PSL therapy, although the relationship between the fracture and PSL therapy was uncertain.

[ [ "PSL", "Fracture of the femoral neck" ] ]

Visual loss after a single small dose of vincristine has never been reported.

[ [ "vincristine", "Visual loss" ] ]

Massive CBZ OD may produce a reversible encephalopathy that includes cortical hyperexcitability, a profound burst-suppression EEG pattern, and cranial nerve areflexia.

[ [ "CBZ", "cranial nerve areflexia" ], [ "CBZ", "cortical hyperexcitability" ], [ "CBZ", "profound burst-suppression EEG pattern" ], [ "CBZ", "reversible encephalopathy" ] ]

When measured, the serum lithium level had increased 4-fold during acyclovir therapy.

[ [ "acyclovir", "serum lithium level had increased" ], [ "lithium", "serum lithium level had increased" ] ]

Ezetimibe-induced acute pancreatitis.

[ [ "Ezetimibe", "acute pancreatitis" ] ]

The ulcer did not respond to antibiotic treatment and healed shortly after withholding ATRA.

[ [ "ATRA", "ulcer" ] ]

Multiple pulmonary nodules: an unusual presentation of fludarabine pulmonary toxicity: case report and review of literature.

[ [ "fludarabine", "pulmonary toxicity" ], [ "fludarabine", "Multiple pulmonary nodules" ] ]

Fulminant hepatic failure associated with bicalutamide.

[ [ "bicalutamide", "Fulminant hepatic failure" ] ]

These in vitro findings and clinical course suggest that TRAb/TBII without thyroid-stimulating activity may develop in patients with amiodarone-induced destructive thyroiditis, as reported in patients with destructive thyroiditis, such as subacute and silent thyroiditis.

[ [ "amiodarone", "TRAb/TBII without thyroid-stimulating activity" ], [ "amiodarone", "thyroiditis" ], [ "amiodarone", "destructive thyroiditis" ] ]

The newborn manifested a four day course of lethargy with unexplained high lithium levels in the adult toxic range.

[ [ "lithium", "lethargy" ] ]

Spindle coma in benzodiazepine toxicity: case report.

[ [ "benzodiazepine", "Spindle coma" ] ]

Sudden cardiac death due to hypersensitivity myocarditis during clozapine treatment.

[ [ "clozapine", "Sudden cardiac death" ], [ "clozapine", "hypersensitivity myocarditis" ] ]

PATIENT AND METHOD: A 34-year-old woman with chronic hepatitis C, genotype 3, receiving pegylated interferon alpha-2a and ribavirin for 6 months, developed progressive malaise and anemia 6 months after the end of treatment.

[ [ "ribavirin", "anemia" ], [ "pegylated interferon alpha-2a", "anemia" ], [ "pegylated interferon alpha-2a", "progressive malaise" ], [ "ribavirin", "progressive malaise" ] ]

Multiple myeloma complicated by congestive heart failure following first administration of recombinant alpha-interferon.

[ [ "recombinant alpha-interferon", "congestive heart failure" ] ]

However, a large case-control study included three cases of either Stevens-Johnson syndrome or toxic epidermal necrolysis associated with ofloxacin use, but no details of the cases were given.

[ [ "ofloxacin", "toxic epidermal necrolysis" ], [ "ofloxacin", "Stevens-Johnson syndrome" ] ]

Foscarnet-induced severe hypomagnesemia and other electrolyte disorders.

[ [ "Foscarnet", "electrolyte disorders" ], [ "Foscarnet", "severe hypomagnesemia" ] ]

Intravenous valproate associated with significant hypotension in the treatment of status epilepticus.

[ [ "valproate", "hypotension" ] ]

To our knowledge, this is the first case of spontaneous remission of MTX-associated gastric LPD after discontinuation of MTX therapy.

[ [ "MTX", "gastric LPD" ] ]

Ofloxacin: a probable cause of toxic epidermal necrolysis.

[ [ "Ofloxacin", "toxic epidermal necrolysis" ] ]

Trimethoprim-sulfamethoxazole-induced aseptic meningitis.

[ [ "Trimethoprim-sulfamethoxazole", "aseptic meningitis" ] ]

Hepatotoxicity induced by cyproterone acetate: a report of three cases.

[ [ "cyproterone acetate", "Hepatotoxicity" ] ]

Prolongation of the QT interval observed in a Japanese patient with vivax malaria following treatment with halofantrine.

[ [ "halofantrine", "Prolongation of the QT interval" ] ]

We report a case of radiotherapy-enhanced aminoglutethimide skin toxicity in a patient with metastatic breast cancer.

[ [ "aminoglutethimide", "skin toxicity" ] ]

Acute myocardial ischemia following accidental intravenous administration of epinephrine in high concentration.

[ [ "epinephrine", "Acute myocardial ischemia" ] ]

After nine previous uncomplicated cycles she developed severe anaphylaxis to cisplatin.

[ [ "cisplatin", "anaphylaxis" ] ]

A 16-year-old boy developed fever, generalized rigidity, leukocytosis, and increased serum transaminase and creatine kinase levels while receiving treatment with olanzapine and lithium.

[ [ "olanzapine", "generalized rigidity" ], [ "olanzapine", "leukocytosis" ], [ "olanzapine", "fever" ], [ "lithium", "fever" ], [ "lithium", "leukocytosis" ], [ "lithium", "increased serum transaminase and creatine kinase" ], [ "olanzapine",...

A case of phenobarbital exacerbation of a preexisting maladaptive behavior partially suppressed by chlorpromazine and misinterpreted as chlorpromazine efficacy.

[ [ "phenobarbital", "exacerbation of a preexisting maladaptive behavior" ] ]

Cardiac arrest after esmolol administration: a review of acute beta-blocker toxicity.

[ [ "esmolol", "Cardiac arrest" ] ]

Interference with the cortisol axis by the microtubule antagonist, CPH82.

[ [ "CPH82", "Interference with the cortisol axis" ] ]

A patient is described who developed a poorly differentiated sarcoma after cyclophosphamide was used to treat his rheumatoid arthritis.

[ [ "cyclophosphamide", "sarcoma" ] ]

Seventy-four per cent of patients with epileptogenic disorders seen at the Emergency Unit at Groote Schuur Hospital were on phenytoin and 11.6% of these had blood levels in the toxic range.

[ [ "phenytoin", "blood levels in the toxic range" ] ]

CONCLUSIONS: Peripheral administration of low-dose vasopressin for septic shock should be discouraged because of the risk of ischemic skin complications.

[ [ "vasopressin", "ischemic skin complications" ] ]

Transient global amnesia after clioquinol: five personal observations from outside Japan.

[ [ "clioquinol", "Transient global amnesia" ] ]

Withdrawal of Depakote resulted in resolution of the effusion.

[ [ "Depakote", "effusion" ] ]

Thoracoscopic biopsy to confirm metastasis revealed instead fibrotic lesions apparently attributable to bleomycin or cyclophosphamide.

[ [ "cyclophosphamide", "fibrotic lesions" ], [ "bleomycin", "fibrotic lesions" ] ]

We report the first case of acute renal failure with hyperkalemia associated with the recently marketed direct renin inhibitor aliskiren.

[ [ "aliskiren", "hyperkalemia" ], [ "aliskiren", "acute renal failure" ] ]

We describe two ELBW infants affected by hyperkalaemia, treated with Kayexalate, who developed serious hypernatraemia, that has never been reported before in preterm infants.

[ [ "Kayexalate", "hypernatraemia" ] ]

The mechanism of RTA induced by FK506 has not yet been clearly elucidated.

[ [ "FK506", "RTA" ] ]

We describe 2 cases of SJS related to nevirapine use and review the literature on this newly recognized association.

[ [ "nevirapine", "SJS" ] ]

Osteonecrosis is a serious side effect of antiemetic treatment with dexamethasone and this serious complication should be incorporated in the current guidelines.

[ [ "dexamethasone", "Osteonecrosis" ] ]

Adenosine-induced ventricular fibrillation.

[ [ "Adenosine", "ventricular fibrillation" ] ]

The cause of his bleeding was a severe thrombocytopoaenia, induced by chronic ingestion of quinine.

[ [ "quinine", "severe thrombocytopoaenia" ] ]

Horner's syndrome and demyelinating peripheral neuropathy caused by high-dose cytosine arabinoside.

[ [ "cytosine arabinoside", "demyelinating peripheral neuropathy" ], [ "cytosine arabinoside", "Horner's syndrome" ] ]

Carbamazepine-induced hyperammonemia.

[ [ "Carbamazepine", "hyperammonemia" ] ]

Corneal endothelial deposits associated with rifabutin use.

[ [ "rifabutin", "Corneal endothelial deposits" ] ]

CONCLUSIONS: There is very little published information regarding ofloxacin-induced toxic epidermal necrolysis.

[ [ "ofloxacin", "toxic epidermal necrolysis" ] ]

We report three cases of severe hepatotoxicity related to benzarone, a benzofuran derivative.

[ [ "benzarone", "severe hepatotoxicity" ] ]

The results clearly demonstrate that CPH82 was associated with suppression of the endogeneous production of ACTH and cortisol with a concomitant paradoxical picture of clinical hypercortisolism.

[ [ "CPH82", "hypercortisolism" ], [ "CPH82", "suppression of the endogeneous production of ACTH and cortisol" ] ]

Severe acidosis from acetazolamide in a diabetic patient.

[ [ "acetazolamide", "Severe acidosis" ] ]

Rupture of a cerebral aneurysm associated with nifedipine treatment.

[ [ "nifedipine", "Rupture of a cerebral aneurysm" ] ]

CONCLUSION: The findings in these two patients suggest that colchicine may delay corneal wound healing.

[ [ "colchicine", "delay corneal wound healing" ] ]

We describe a 74-year-old man with rheumatoid arthritis (RA) who developed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) 1.5 months after commencement of mizoribin prescription when his arthritis was improved.

[ [ "mizoribin", "syndrome of inappropriate secretion of antidiuretic hormone" ], [ "mizoribin", "SIADH" ] ]

Theoretical basal ganglia toxicologic mechanisms of methanol poisoning are reviewed, and the role of brain imaging studies will regard to diagnosis, prognosis and impact on management is discussed.

[ [ "methanol", "methanol poisoning" ] ]

We present a case report of a patient who developed a prolonged QT while being treated with oral methadone for a chronic pain syndrome.

[ [ "methadone", "prolonged QT" ] ]

We describe 2 children with cerebral palsy who suffered significant morbidity immediately after treatment with hyperbaric oxygen.

[ [ "hyperbaric oxygen", "morbidity" ] ]

We report on three observations of parkinsonian patients with levo-dopa-induced diphasic dyskinesias, who received subcutaneous apomorphine to reduce the duration of abnormal movements.

[ [ "levo-dopa", "diphasic dyskinesias" ] ]

BACKGROUND: Gemcitabine has mild renal toxicity, but cases of gemcitabine-associated hemolytic-uremic syndrome (HUS) have been reported.

[ [ "gemcitabine", "hemolytic-uremic syndrome" ], [ "Gemcitabine", "HUS" ], [ "gemcitabine", "HUS" ], [ "Gemcitabine", "renal toxicity" ], [ "Gemcitabine", "hemolytic-uremic syndrome" ] ]

A 59-year-old woman with myasthenia gravis who received a large dose of pyridostigmine bromide developed postoperative psychosis and was diagnosed as having bromide intoxication.

[ [ "pyridostigmine bromide", "bromide intoxication" ], [ "pyridostigmine bromide", "postoperative psychosis" ] ]

Capecitabine-induced headache responding to diltiazem.

[ [ "Capecitabine", "headache" ] ]

Acute non-lymphocytic leukemia in patients with ovarian carcinoma following long-term treatment with Treosulfan (= dihydroxybusulfan).

[ [ "Treosulfan", "Acute non-lymphocytic leukemia" ], [ "dihydroxybusulfan", "Acute non-lymphocytic leukemia" ] ]

Based on the Naranjo probability scale, serotonin syndrome was a probable adverse reaction associated with co-administration of citalopram and fentanyl.

[ [ "citalopram", "serotonin syndrome" ], [ "fentanyl", "serotonin syndrome" ] ]

The incidence of oral-verapamil-induced hypotension in the presence of concomitant beta-adrenergic blockade by the oral route is quite rare.

[ [ "verapamil", "hypotension" ] ]

Acute acoustic nerve palsy associated with vincristine therapy.

[ [ "vincristine", "Acute acoustic nerve palsy" ] ]

Disopyramide (Norpace)-induced hypoglycemia.

[ [ "Disopyramide", "hypoglycemia" ], [ "Norpace", "hypoglycemia" ] ]

We report 5 patients (3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated ...

[ [ "pegylated interferon alfa-2b", "local cutaneous reactions" ], [ "ribavirin", "local cutaneous reactions" ] ]

Capecitabine-induced multifocal leukoencephalopathy: a report of five cases.

[ [ "Capecitabine", "multifocal leukoencephalopathy" ] ]

This report highlights a case of drug-induced dysphagia in a patient receiving haloperidol for obsessive nocturnal thoughts and auditory disturbances.

[ [ "haloperidol", "dysphagia" ] ]

The currently available clinical and neuropharmacologic data suggest that carbamazepine may be an antagonist of dopamine and that this property is responsible for the production of dystonia.

[ [ "carbamazepine", "dystonia" ] ]

One patient had severe temporary weakness after an ampicillin sodium challenge.

[ [ "ampicillin sodium", "severe temporary weakness" ] ]

Effect of beta-blockade on symptomatic dexamethasone-induced hypertrophic obstructive cardiomyopathy in premature infants: three case reports and literature review.

[ [ "dexamethasone", "hypertrophic obstructive cardiomyopathy" ] ]