harpreetmann/entity_extraction_ade · Datasets at Hugging Face

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The authors describe a case of interstitial granulomatous dermatitis associated with darifenacin.	[ [ "darifenacin", "interstitial granulomatous dermatitis" ] ]
When DSCG was withdrawn, urticaria vanished and the child remained symptom-free.	[ [ "DSCG", "urticaria" ] ]
Retinopathy in hepatitis C patients due to combination therapy with pegylated interferon and ribavirin.	[ [ "ribavirin", "Retinopathy" ], [ "pegylated interferon", "Retinopathy" ] ]
Torsade de pointes during loading with amiodarone.	[ [ "amiodarone", "Torsade de pointes" ] ]
An amiodarone optic neuropathy has been described.	[ [ "amiodarone", "optic neuropathy" ] ]
Prior to surgery, levodopa induced dyskinesia had improved (< or = 50%) under treatment with amantadine (400 mg/day, po) in all three patients.	[ [ "levodopa", "dyskinesia" ] ]
METHODS: Double-blind, placebo-controlled titrated oral challenges with pancreatic enzymes resulted in definite vomiting within 1 to 1.5 hours after challenges with Viokase and Pancrease MT 16, but not with placebo.	[ [ "Viokase", "vomiting" ], [ "Pancrease MT 16", "vomiting" ] ]
It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome.	[ [ "dapsone", "hypersensitivity syndrome" ] ]
The failure of therapy with disopyramide and mexiletine to reproduce this observation suggests either a previously unreported electrophysiologic effect of, or idiosyncratic response to, procainamide.	[ [ "procainamide", "electrophysiologic effect" ] ]
Acute intravascular hemolysis developed when a diabetic patient, previously treated with glyburide, was started on another oral sulfonylurea drug, chlorpropamide.	[ [ "glyburide", "Acute intravascular hemolysis" ], [ "chlorpropamide", "Acute intravascular hemolysis" ] ]
Linezolid-associated acute interstitial nephritis and drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.	[ [ "Linezolid", "DRESS" ], [ "Linezolid", "drug rash with eosinophilia and systemic symptoms" ], [ "Linezolid", "acute interstitial nephritis" ] ]
Complications of chemotherapy for a synovial sarcoma in an eight-year old boy included cisplatinum nephrotoxicity and adriamycin cardiotoxicity.	[ [ "cisplatinum", "nephrotoxicity" ], [ "adriamycin", "cardiotoxicity" ] ]
Triazolam-induced nocturnal bingeing with amnesia.	[ [ "Triazolam", "amnesia" ], [ "Triazolam", "nocturnal bingeing" ] ]
When vague symptoms develop during desmopressin therapy, hyponatremia must be considered as part of the differential diagnosis.	[ [ "desmopressin", "vague symptoms" ], [ "desmopressin", "hyponatremia" ] ]
A drug addict with staphylococcal endocarditis treated with methicillin, who developed massive proteinuria and acute nephritic syndrome is described.	[ [ "methicillin", "massive proteinuria" ], [ "methicillin", "acute nephritic syndrome" ] ]
Withdrawal emergent syndrome in an infant associated with maternal haloperidol therapy.	[ [ "haloperidol", "Withdrawal emergent syndrome" ] ]
Three patients receiving gold salt treatment for rheumatoid arthritis developed severe aplastic anemia.	[ [ "gold", "aplastic anemia" ] ]
Aliskiren-associated acute renal failure with hyperkalemia.	[ [ "Aliskiren", "acute renal failure" ] ]
Lower extremity arterial insufficiency after long-term methysergide maleate therapy.	[ [ "methysergide maleate", "arterial insufficiency" ] ]
Hepatotoxicity related to itraconazole: report of three cases.	[ [ "itraconazole", "Hepatotoxicity" ] ]
We report a case of unintentional overdose of oral pilocarpine tablets that resulted in bradycardia, mild hypotension, and muscarinic symptoms in a patient with Sjogren's syndrome.	[ [ "pilocarpine", "mild hypotension" ], [ "pilocarpine", "muscarinic symptoms" ], [ "pilocarpine", "bradycardia" ] ]
We report the first case of an acute flare of eosinophilic cystitis in a 51-year-old woman after bladder instillation with dimethyl sulfoxide (DMSO) for presumed interstitial cystitis.	[ [ "dimethyl sulfoxide", "eosinophilic cystitis" ], [ "DMSO", "eosinophilic cystitis" ] ]
OBJECTIVE: To report teicoplanin-related neutropenia that developed after an episode of neutropenia induced by vancomycin therapy.	[ [ "vancomycin", "neutropenia" ], [ "teicoplanin", "neutropenia" ] ]
Intraventricular vancomycin-induced cerebrospinal fluid eosinophilia: report of two patients.	[ [ "vancomycin", "cerebrospinal fluid eosinophilia" ] ]
We present a case of stroke after PPA ingestion that occurred 4 months after the recall in an 8-year-old boy on chronic peritoneal dialysis.	[ [ "PPA", "stroke" ] ]
We describe a case of ulcerative proctitis after ibuprofen treatment in a girl with juvenile systemic lupus erythematosus.	[ [ "ibuprofen", "ulcerative proctitis" ] ]
CASE: We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.	[ [ "tacrolimus", "worsening of chronic aphthous ulcers" ], [ "sirolimus", "worsening of chronic aphthous ulcers" ] ]
Linear IgA bullous dermatosis occurring after carbamazepine.	[ [ "carbamazepine", "Linear IgA bullous dermatosis" ] ]
We observed transient panhypogammaglobulinaemia in a patient with neuropsychiatric SLE after treatment with prednisolone and cyclophosphamide.	[ [ "prednisolone", "panhypogammaglobulinaemia" ], [ "cyclophosphamide", "panhypogammaglobulinaemia" ] ]
The patient was found to have no motile sperm with a normal sperm count, while taking a dose of 400 mg/day of carbamazepine.	[ [ "carbamazepine", "no motile sperm" ] ]
The first known report of quetiapine exacerbating OCS in a 43-year-old man with obsessive-compulsive disorder (OCD), trichotillomania, delusional disorder and bipolar II disorder is presented.	[ [ "quetiapine", "exacerbating OCS" ] ]
This case report illustrates the use of continuous high-dose intracoronary nitroglycerin infusion through a 6 French coronary guiding catheter in the treatment of a patient with cocaine-induced refractory coronary vasospasm.	[ [ "cocaine", "refractory coronary vasospasm" ] ]
Generalized argyria after habitual use of AgNO3.	[ [ "AgNO3", "Generalized argyria" ] ]
Animals treated with HAL showed a highly significant 32%-46% loss of tyrosine hydroxylase (TH) immunoreactive neurons in the substantia nigra, and 20% contraction of the TH stained dendritic arbour.	[ [ "HAL", "significant 32%-46% loss of tyrosine hydroxylase (TH) immunoreactive neurons" ] ]
Central nervous system toxicity associated with meperidine use in hepatic disease.	[ [ "meperidine", "Central nervous system toxicity" ] ]
CONCLUSION: Long-term treatment with rifabutin may have a reversible and previously undescribed side-effect on retinal function.	[ [ "rifabutin", "side-effect on retinal function" ] ]
The development of an IgG lambda-type monoclonal gammopathy and subsequent multiple myeloma in an epilepsy patient on diphenylhydantoin (DILANTIN) therapy for 20 years is reported.	[ [ "DILANTIN", "multiple myeloma" ], [ "diphenylhydantoin", "multiple myeloma" ], [ "diphenylhydantoin", "IgG lambda-type monoclonal gammopathy" ], [ "DILANTIN", "IgG lambda-type monoclonal gammopathy" ] ]
L-asparaginase-induced pancreatitis is an uncommon but potential lethal complication of the treatment of leukemia.	[ [ "L-asparaginase", "pancreatitis" ], [ "L-asparaginase", "lethal complication" ] ]
We believe the temporal association of the abnormal liver enzymes in this patient, in the absence of other offending agents, argues strongly in favor of 6-TG as a cause of liver enzyme abnormalities.	[ [ "6-TG", "abnormal liver enzymes" ], [ "6-TG", "liver enzyme abnormalities" ] ]
BACKGROUND: Accutane a teratogenic prescription drug licensed to treat severe, recalcitrant nodular acne.	[ [ "Accutane", "teratogenic" ] ]
Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).	[ [ "8-MOP", "Systemic allergic contact dermatitis" ], [ "8-methoxypsoralen", "Systemic allergic contact dermatitis" ] ]
Diabetes Mellitus was observed in a patient given carbamazepine.	[ [ "carbamazepine", "Diabetes Mellitus" ] ]
Bronchiolitis obliterans with organizing pneumonia after rituximab therapy for non-Hodgkin's lymphoma.	[ [ "rituximab", "Bronchiolitis obliterans with organizing pneumonia" ] ]

The authors describe a case of interstitial granulomatous dermatitis associated with darifenacin.

[ [ "darifenacin", "interstitial granulomatous dermatitis" ] ]

When DSCG was withdrawn, urticaria vanished and the child remained symptom-free.

[ [ "DSCG", "urticaria" ] ]

Retinopathy in hepatitis C patients due to combination therapy with pegylated interferon and ribavirin.

[ [ "ribavirin", "Retinopathy" ], [ "pegylated interferon", "Retinopathy" ] ]

Torsade de pointes during loading with amiodarone.

[ [ "amiodarone", "Torsade de pointes" ] ]

An amiodarone optic neuropathy has been described.

[ [ "amiodarone", "optic neuropathy" ] ]

Prior to surgery, levodopa induced dyskinesia had improved (< or = 50%) under treatment with amantadine (400 mg/day, po) in all three patients.

[ [ "levodopa", "dyskinesia" ] ]

METHODS: Double-blind, placebo-controlled titrated oral challenges with pancreatic enzymes resulted in definite vomiting within 1 to 1.5 hours after challenges with Viokase and Pancrease MT 16, but not with placebo.

[ [ "Viokase", "vomiting" ], [ "Pancrease MT 16", "vomiting" ] ]

It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome.

[ [ "dapsone", "hypersensitivity syndrome" ] ]

The failure of therapy with disopyramide and mexiletine to reproduce this observation suggests either a previously unreported electrophysiologic effect of, or idiosyncratic response to, procainamide.

[ [ "procainamide", "electrophysiologic effect" ] ]

Acute intravascular hemolysis developed when a diabetic patient, previously treated with glyburide, was started on another oral sulfonylurea drug, chlorpropamide.

[ [ "glyburide", "Acute intravascular hemolysis" ], [ "chlorpropamide", "Acute intravascular hemolysis" ] ]

Linezolid-associated acute interstitial nephritis and drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.

[ [ "Linezolid", "DRESS" ], [ "Linezolid", "drug rash with eosinophilia and systemic symptoms" ], [ "Linezolid", "acute interstitial nephritis" ] ]

Complications of chemotherapy for a synovial sarcoma in an eight-year old boy included cisplatinum nephrotoxicity and adriamycin cardiotoxicity.

[ [ "cisplatinum", "nephrotoxicity" ], [ "adriamycin", "cardiotoxicity" ] ]

Triazolam-induced nocturnal bingeing with amnesia.

[ [ "Triazolam", "amnesia" ], [ "Triazolam", "nocturnal bingeing" ] ]

When vague symptoms develop during desmopressin therapy, hyponatremia must be considered as part of the differential diagnosis.

[ [ "desmopressin", "vague symptoms" ], [ "desmopressin", "hyponatremia" ] ]

A drug addict with staphylococcal endocarditis treated with methicillin, who developed massive proteinuria and acute nephritic syndrome is described.

[ [ "methicillin", "massive proteinuria" ], [ "methicillin", "acute nephritic syndrome" ] ]

Withdrawal emergent syndrome in an infant associated with maternal haloperidol therapy.

[ [ "haloperidol", "Withdrawal emergent syndrome" ] ]

Three patients receiving gold salt treatment for rheumatoid arthritis developed severe aplastic anemia.

[ [ "gold", "aplastic anemia" ] ]

Aliskiren-associated acute renal failure with hyperkalemia.

[ [ "Aliskiren", "acute renal failure" ] ]

Lower extremity arterial insufficiency after long-term methysergide maleate therapy.

[ [ "methysergide maleate", "arterial insufficiency" ] ]

Hepatotoxicity related to itraconazole: report of three cases.

[ [ "itraconazole", "Hepatotoxicity" ] ]

We report a case of unintentional overdose of oral pilocarpine tablets that resulted in bradycardia, mild hypotension, and muscarinic symptoms in a patient with Sjogren's syndrome.

[ [ "pilocarpine", "mild hypotension" ], [ "pilocarpine", "muscarinic symptoms" ], [ "pilocarpine", "bradycardia" ] ]

We report the first case of an acute flare of eosinophilic cystitis in a 51-year-old woman after bladder instillation with dimethyl sulfoxide (DMSO) for presumed interstitial cystitis.

[ [ "dimethyl sulfoxide", "eosinophilic cystitis" ], [ "DMSO", "eosinophilic cystitis" ] ]

OBJECTIVE: To report teicoplanin-related neutropenia that developed after an episode of neutropenia induced by vancomycin therapy.

[ [ "vancomycin", "neutropenia" ], [ "teicoplanin", "neutropenia" ] ]

Intraventricular vancomycin-induced cerebrospinal fluid eosinophilia: report of two patients.

[ [ "vancomycin", "cerebrospinal fluid eosinophilia" ] ]

We present a case of stroke after PPA ingestion that occurred 4 months after the recall in an 8-year-old boy on chronic peritoneal dialysis.

[ [ "PPA", "stroke" ] ]

We describe a case of ulcerative proctitis after ibuprofen treatment in a girl with juvenile systemic lupus erythematosus.

[ [ "ibuprofen", "ulcerative proctitis" ] ]

CASE: We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.

[ [ "tacrolimus", "worsening of chronic aphthous ulcers" ], [ "sirolimus", "worsening of chronic aphthous ulcers" ] ]

Linear IgA bullous dermatosis occurring after carbamazepine.

[ [ "carbamazepine", "Linear IgA bullous dermatosis" ] ]

We observed transient panhypogammaglobulinaemia in a patient with neuropsychiatric SLE after treatment with prednisolone and cyclophosphamide.

[ [ "prednisolone", "panhypogammaglobulinaemia" ], [ "cyclophosphamide", "panhypogammaglobulinaemia" ] ]

The patient was found to have no motile sperm with a normal sperm count, while taking a dose of 400 mg/day of carbamazepine.

[ [ "carbamazepine", "no motile sperm" ] ]

The first known report of quetiapine exacerbating OCS in a 43-year-old man with obsessive-compulsive disorder (OCD), trichotillomania, delusional disorder and bipolar II disorder is presented.

[ [ "quetiapine", "exacerbating OCS" ] ]

This case report illustrates the use of continuous high-dose intracoronary nitroglycerin infusion through a 6 French coronary guiding catheter in the treatment of a patient with cocaine-induced refractory coronary vasospasm.

[ [ "cocaine", "refractory coronary vasospasm" ] ]

Generalized argyria after habitual use of AgNO3.

[ [ "AgNO3", "Generalized argyria" ] ]

Animals treated with HAL showed a highly significant 32%-46% loss of tyrosine hydroxylase (TH) immunoreactive neurons in the substantia nigra, and 20% contraction of the TH stained dendritic arbour.

[ [ "HAL", "significant 32%-46% loss of tyrosine hydroxylase (TH) immunoreactive neurons" ] ]

Central nervous system toxicity associated with meperidine use in hepatic disease.

[ [ "meperidine", "Central nervous system toxicity" ] ]

CONCLUSION: Long-term treatment with rifabutin may have a reversible and previously undescribed side-effect on retinal function.

[ [ "rifabutin", "side-effect on retinal function" ] ]

The development of an IgG lambda-type monoclonal gammopathy and subsequent multiple myeloma in an epilepsy patient on diphenylhydantoin (DILANTIN) therapy for 20 years is reported.

[ [ "DILANTIN", "multiple myeloma" ], [ "diphenylhydantoin", "multiple myeloma" ], [ "diphenylhydantoin", "IgG lambda-type monoclonal gammopathy" ], [ "DILANTIN", "IgG lambda-type monoclonal gammopathy" ] ]

L-asparaginase-induced pancreatitis is an uncommon but potential lethal complication of the treatment of leukemia.

[ [ "L-asparaginase", "pancreatitis" ], [ "L-asparaginase", "lethal complication" ] ]

We believe the temporal association of the abnormal liver enzymes in this patient, in the absence of other offending agents, argues strongly in favor of 6-TG as a cause of liver enzyme abnormalities.

[ [ "6-TG", "abnormal liver enzymes" ], [ "6-TG", "liver enzyme abnormalities" ] ]

BACKGROUND: Accutane a teratogenic prescription drug licensed to treat severe, recalcitrant nodular acne.

[ [ "Accutane", "teratogenic" ] ]

Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).

[ [ "8-MOP", "Systemic allergic contact dermatitis" ], [ "8-methoxypsoralen", "Systemic allergic contact dermatitis" ] ]

Diabetes Mellitus was observed in a patient given carbamazepine.

[ [ "carbamazepine", "Diabetes Mellitus" ] ]

Bronchiolitis obliterans with organizing pneumonia after rituximab therapy for non-Hodgkin's lymphoma.

[ [ "rituximab", "Bronchiolitis obliterans with organizing pneumonia" ] ]