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35,343,076
Intraoperative visualization of urethra using illuminating catheter in laparoscopy-assisted anorectoplasty for imperforated anus-A novel and safe technique for preventing urethral injury.
Asian journal of endoscopic surgery
Asian J Endosc Surg
15
4
10.1111/ases.13061
eng
2,022
10
null
2,022
3
27
[PURPOSE] In this study, we used a near-infrared ray catheter (NIRC) to visualize the urethral line. We herein report our intraoperative visualization technique of the urethra using an illuminating catheter in laparoscopy-assisted anorectoplasty (LAARP) for imperforated anus. [PATIENT AND SURGICAL TECHNIQUE] A 3.0-kg t...
illuminating catheter; imperforated anus; laparoscopy-assisted anorectoplasty
0.297
29
Medicine
Medicine
2,022
35,343,041
Efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in treatment-naïve chronic hepatitis B.
Liver international : official journal of the International Association for the Study of the Liver
Liver Int
42
7
10.1111/liv.15261
eng
2,022
7
null
2,022
4
3
[BACKGROUND AND AIMS] We used real-world data to evaluate the efficacy and safety of tenofovir alafenamide (TAF) compared with tenofovir disoproxil fumarate (TDF) in treatment-naïve patients with CHB. [METHODS] We analysed 2747 patients with CHB under TAF (n = 502) or TDF (n = 2245) treatments. Virological responses (V...
chronic hepatitis B; hepatocellular carcinoma; tenofovir alafenamide; tenofovir disoproxil fumarate
1.929
145
Hepatology
Medicine
2,022
35,342,899
Emergency medical service interpretation of Physician Orders for Life-Sustaining Treatment (POLST) in cardiopulmonary arrest.
Journal of the American College of Emergency Physicians open
J Am Coll Emerg Physicians Open
3
2
10.1002/emp2.12705
eng
2,022
4
null
2,022
3
17
[OBJECTIVE] Physician Orders for Life-Sustaining Treatment (POLST) forms exist in some form in all 50 states. This study evaluates emergency medical service (EMS) practitioners interpretation of the POLST in cardiopulmonary arrest. [METHODS] This study used a prospective convenience sample of California Bay Area EMS pr...
null
null
null
null
null
null
35,342,886
Pharmacogenomics of Hypertension in CKD: The CKD-PGX Study.
Kidney360
Kidney360
3
2
10.34067/kid.0005362021
eng
2,022
2
null
2,022
2
24
[BACKGROUND] Patients with CKD often have uncontrolled hypertension despite polypharmacy. Pharmacogenomic drug-gene interactions (DGIs) may affect the metabolism or efficacy of antihypertensive agents. We report changes in hypertension control after providing a panel of 11 pharmacogenomic predictors of antihypertensive...
null
null
26
Medicine; Nephrology
Medicine
2,022
35,342,828
Combined distal median nerve block and local anesthesia with lidocaine:epinephrine for carpal tunnel release.
Heliyon
Heliyon
8
3
10.1016/j.heliyon.2022.e09119
eng
2,022
3
null
2,022
3
16
[AIM] Evaluating patient comfort during full awake local anesthesia in carpal tunnel release surgery, without tourniquet use, by using epinephrine to obtain a completely dry surgical field. [METHODS] We included into the study 41 patients who underwent carpal tunnel syndrome surgery under full awake combined anesthesia...
Anesthesia; Carpal tunnel; Epinephrine; Lidocaine
0.609
115
Multidisciplinary
Multidisciplinary
2,022
35,342,774
Utilization of Preconception Care and Its Associated Factors among Pregnant Women of West Guji Zone, Oromia, Ethiopia, 2021: A Community-Based Cross-Sectional Study.
Health services research and managerial epidemiology
Health Serv Res Manag Epidemiol
9
null
10.1177/23333928221088720
eng
2,022
null
null
2,022
3
21
[BACKGROUND] Regardless of its benefit in promoting maternal health, contributing to a healthy pregnancy, little is known concerning the prevalence of utilization of preconception care and its determinant in southern Ethiopia. Hence, this study designed to determine the prevalence of utilization of preconception care a...
associated factors; preconception care; pregnant women
0.357
16
Health Policy; Epidemiology
Medicine
2,022
35,342,690
Impact of 719Trp>Arg Polymorphism of KIF 6 Gene on Contrast Induced Nephropathy in Patients Undergoing Coronary Angiography or Percutaneous Coronary Intervention.
Global heart
Glob Heart
17
1
10.5334/gh.1105
eng
2,022
null
null
2,022
2
28
[BACKGROUND] The identification of preventive strategies, such as statin therapy, is crucial for the management of contrast-induced nephropathy (CIN). Several studies showed the association between KIF6 polymorphism (replacement of Trp719 with Arg) and an increased cardiovascular risk, while others showed a correlation...
KIF 6 polymorphism; contrast induced nephropathy; interventional cardiology
0.87
55
Community and Home Care; Cardiology and Cardiovascular Medicine; Epidemiology
Medicine; Nursing
2,022
35,342,437
The effectiveness of olibanum orally disintegrating tablet in the treatment of oral aphthous ulcers: A randomized, double-blind, placebo-controlled clinical trial.
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
J Res Med Sci
27
null
10.4103/jrms.jrms_247_21
eng
2,022
null
null
2,022
1
29
[BACKGROUND] Boswellia serrata oleo-gum-resin (frankincense; olibanum) has anti-inflammatory, analgesic, and antimicrobial effects. This study aimed to evaluate the clinical effectiveness of frankincense extract in the treatment of oral aphthous ulcers. [MATERIALS AND METHODS] In a randomized, double-blind, placebo-con...
Boswellia serrata; Frankincense; clinical trial; olibanum; oral aphthous ulcer
0.41
59
Medicine
Medicine
2,022
35,342,426
Accuracy of Estimating Periodontitis and Its Risk Association Using Partial-Mouth Recordings for Surveillance Studies: A Systematic Review and Meta-Analysis.
International journal of dentistry
Int J Dent
2022
null
10.1155/2022/7961199
eng
2,022
null
null
2,022
3
17
[OBJECTIVES] Our aim is to conduct an up-to-date systematic review and meta-analysis pertaining to the accuracy of using the partial-mouth recording protocol (PRP) in surveillance studies to estimate the periodontitis prevalence, extent, severity, and its risk associations. [METHODS] Medline and Embase databases were s...
null
0.47
57
Dentistry
Dentistry
2,022
35,342,235
Headache Incidence and Characteristics in COVID-19 Patients: A Hospital-Based Study.
Annals of Indian Academy of Neurology
Ann Indian Acad Neurol
25
1
10.4103/aian.aian_244_21
eng
2,022
null
null
2,021
11
29
[BACKGROUND] Headache is one of the commonly reported symptoms of coronavirus disease-2019 (COVID-19) illness. A number of studies have been done so far focusing on headache associated with COVID-19 with variable incidence and characteristics. [MATERIAL AND METHODS] This study is a prospective study conducted on 120 pa...
COVID-19; headache; pandemic
0.334
46
Neurology
Medicine
2,022
35,342,026
Readability of Online Spine Patient Education Resources.
World neurosurgery
World Neurosurg
162
null
10.1016/j.wneu.2022.03.091
eng
2,022
6
null
2,022
3
25
[OBJECTIVE] We assessed the readability of spine-related patient education materials on professional society websites to determine whether this had improved since last studied. We also compared the readability of these materials to a more patient-centered source, such as WebMD. [METHODS] Patient education pages from th...
Online resources; Patient education; Readability; Spine
0.591
123
Neurology; Surgery
Medicine
2,022
35,341,590
CC group of chemokines and associated gene expression of transcription factors: Deciphering immuno-pathogenetic aspect of oral submucous fibrosis.
Disease-a-month : DM
Dis Mon
69
1
10.1016/j.disamonth.2022.101351
eng
2,023
1
null
2,022
3
25
[BACKGROUND] Oral submucous fibrosis (OSMF) is a chronic disease with significantly increasing malignant transformation rate. To date the pathogenesis of OSMF has been considered to be associated with areca nut constituents and their action on fibroblasts. However, fibrosis is also associated with immunological factors...
Chemokines; Gene expression; Oral submucous fibrosis
null
null
null
null
null
35,341,148
TCM Syndrome Recognition Model of Type 2 Diabetes Mellitus in Shanghai Based on TCM Inquiry Information.
Evidence-based complementary and alternative medicine : eCAM
Evid Based Complement Alternat Med
2022
null
10.1155/2022/2843218
eng
2,022
null
null
2,022
3
15
[BACKGROUND] Type 2 diabetes mellitus (T2DM) has become one of the serious public health problems in China, and it affects the quality of survival of patients significantly. The long-term monitoring and early warning of T2DM and its complications should be paid attention to. Artificial diagnosis of T2DM in traditional ...
null
null
null
null
null
null
35,341,047
Immediate and cumulative effects of upper-body isometric exercise on the cornea and anterior segment of the human eye.
PeerJ
PeerJ
10
null
10.7717/peerj.13160
eng
2,022
null
null
2,022
3
21
[OBJECTIVES] The execution of isometric resistance training has demonstrated to cause changes in the ocular physiology. The morphology of the cornea and anterior chamber is of paramount importance in the prevention and management of several ocular diseases, and thus, understating the impact of performing isometric exer...
Corneal ectasia; Pentacam; Physical exercise; Pupil size
0.695
124
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,022
35,340,706
Training on a virtual reality cricothyroidotomy simulator improves skills and transfers to a simulated procedure.
Trauma surgery & acute care open
Trauma Surg Acute Care Open
7
1
10.1136/tsaco-2021-000826
eng
2,022
null
null
2,022
3
1
[OBJECTIVE] The virtual airway skills trainer (VAST) is a virtual reality simulator for training in cricothyroidotomy (CCT). The goal of the study is to test the effectiveness of training and transfer of skills of the VAST-CCT. [METHODS] Two groups, control (no training) and simulation (2 weeks of proficiency-based tra...
assessment; virtual reality
null
null
null
null
null
35,340,537
Perioperative Hypertension Etiologies in Patients Undergoing Noncardiac Surgery in University Health Network Hospitals-Canada from 2015-2020.
Integrated blood pressure control
Integr Blood Press Control
15
null
10.2147/IBPC.S347395
eng
2,022
null
null
2,022
3
19
[INTRODUCTION] Perioperative hypertension, defined as increased blood pressure around the surgery, is a known risk factor for perioperative complications, including cardiovascular events. Identifying reasons associated with hypertension in each period is of great help in preventing and better managing perioperative hyp...
hypertension; intraoperative; perioperative; postoperative; surgery
null
null
null
null
null
35,340,502
A Cross-Sectional Study of Serum Glutathione Peroxidase: An Antioxidative Marker in Chronic Periodontitis and Chronic Kidney Disease.
Cureus
Cureus
14
2
10.7759/cureus.22016
eng
2,022
2
null
2,022
2
8
[BACKGROUND AND AIM] Oxidative stress as an individual risk for periodontitis and chronic kidney disease (CKD) has been elaborated through various mechanical pathways, yet its role in association with both diseases remains unexplored. Thus, the current study aims in evaluating serum glutathione peroxidase, an oxidative...
biomarker; chronic periodontitis; comorbidities; infection; oxidative stress; renal disease; serum glutathione peroxidase; systemic interactions
null
null
null
null
null
35,340,304
Cognitive function following SARS-CoV-2 infection in a population-representative Canadian sample.
Brain, behavior, & immunity - health
Brain Behav Immun Health
21
null
10.1016/j.bbih.2022.100454
eng
2,022
5
null
2,022
3
21
[BACKGROUND] SARS-CoV-2 infection is believed to adversely affect the brain, but the degree of impact on socially relevant cognitive functioning and decision-making is not well-studied, particularly among those less vulnerable to age-related mortality. The current study sought to determine whether infection status and ...
Brain; COVID-19; Cognition; Delay discounting; Executive function; OFC; SARS-CoV-2
null
null
null
null
null
35,340,107
Evaluation of the safety and efficacy of a biosimilar abobotulinum toxin type A in treating moderate-to-severe glabellar lines: A non-inferiority double blinded randomized controlled trial.
Journal of cosmetic dermatology
J Cosmet Dermatol
21
6
10.1111/jocd.14939
eng
2,022
6
null
2,022
4
9
[BACKGROUND] Injection of botulinum toxin for cosmetic purposes is a well-established practice. [OBJECTIVES] This study was conducted to compare the safety and efficacy of Dyston[®] (investigational biosimilar abobotulinumtoxinA) with Dysport[®] (abobotulinumtoxinA, Ipsen) in the treatment of moderate-to-severe glabell...
abobotulinumtoxinA; corrugator muscle; glabellar lines; non-inferiority; procerus muscle
0.61
67
Dermatology
Medicine
2,022
35,339,861
Peripheral nerve surgical competency in plastic surgery and neurosurgery residents.
Clinical neurology and neurosurgery
Clin Neurol Neurosurg
216
null
10.1016/j.clineuro.2022.107217
eng
2,022
5
null
2,022
3
22
[OBJECTIVE] To assess the case volume and self-perceived competence of current mandatory skills in peripheral nerve surgery. [DESIGN] Cross sectional survey based study examining case volume and self-reported competence in peripheral nerve surgery. [SETTING] Canadian Neurosurgery and Plastic Surgery accredited residenc...
Competency based training; Nerve surgery; Peripheral nerve; Surgical education
0.538
89
Medicine; Surgery; Neurology
Medicine
2,022
35,339,836
Medication errors by nursing students on clinical practice: An integrative review.
Nurse education today
Nurse Educ Today
112
null
10.1016/j.nedt.2022.105325
eng
2,022
5
null
2,022
3
11
[BACKGROUND] Medication errors are a serious concern and often due to multiple factors. The largest workforce in healthcare are nurses. Nurses play a major role in medication management especially in medication administration. To become proficient in safe medication administration undergraduate nurses, need to be provi...
Clinical placement; Integrative review; Medication administration; Student nurse
0.946
109
Education; Nursing
Nursing; Social Sciences
2,022
35,339,572
Depression reduces neural correlates of reward salience with increasing effort over the course of the progressive ratio task.
Journal of affective disorders
J Affect Disord
307
null
10.1016/j.jad.2022.03.051
eng
2,022
6
15
2,022
3
24
[BACKGROUND] Depressive disorders have been associated with altered effort-cost decision making (ECDM) in behavioral investigations, such as a decreased willingness to expend effort for reward attainment. However, little is known about neural mechanisms implicated in altered ECDM. [METHODS] The study investigates neura...
Depression; Motivation; P300; Progressive ratio; Reward processing
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
35,339,316
Japanese Orthopaedic Association (JOA) clinical practice guidelines on the management of soft tissue tumors 2020 - Secondary publication.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
J Orthop Sci
27
3
10.1016/j.jos.2021.11.023
eng
2,022
5
null
2,022
3
23
[BACKGROUND] These clinical practice guidelines are intended to provide recommendations based on the best evidence obtained to date on key issues in clinical practice to improve the prognosis, diagnostic and therapeutic processes for patients with soft tissue tumors. [METHODS] The Guidelines Development Committee and S...
null
0.44
86
Surgery; Orthopedics and Sports Medicine
Medicine
2,022
35,339,118
RNA in situ hybridisation as a molecular diagnostic technique targeting IBA-1 and CD204 in canine histiocytic sarcoma.
Veterinary medicine and science
Vet Med Sci
8
4
10.1002/vms3.795
eng
2,022
7
null
2,022
3
26
[BACKGROUND] Canine histiocytic sarcoma (HS) is an aggressive cancer with morphologically variable features; therefore, obtaining a definitive diagnosis can be challenging. Two proteins, IBA-1, ionised calcium-binding adapter molecule 1, and CD204, a macrophage scavenger receptor, have been shown to be specific immunoh...
RNAscope; diagnosis; dog; histiocytic disorder; ionised calcium-binding adapter molecule 1; macrophage scavenger receptor
0.451
30
Veterinary
Veterinary
2,022
35,338,625
Increased incidence and aetiological factors of back pain among Universiti Malaysia Sabah staff and undergraduates during the COVID-19 lockdown period.
The Medical journal of Malaysia
Med J Malaysia
77
2
null
eng
2,022
3
null
null
null
null
[INTRODUCTION] In response to the coronavirus disease 2019 (COVID-19) pandemic, many countries have introduced work from home campaigns. Most teaching faculties have moved to an online delivery mode, which could put students and teachers at risk of back pain. The aim of this study was to determine the frequency of newl...
null
null
null
null
null
null
35,338,611
Utility of left atrial and ventricular strain for diagnosis of transthyretin amyloid cardiomyopathy in aortic stenosis.
ESC heart failure
ESC Heart Fail
9
3
10.1002/ehf2.13909
eng
2,022
6
null
2,022
3
25
[AIMS] To clarify the usefulness of left atrial (LA) function and left ventricular (LV) function obtained by two-dimensional (2D) speckle tracking echocardiography to diagnose concomitant transthyretin amyloid cardiomyopathy (ATTR-CM) in patients with aortic stenosis (AS). [METHODS AND RESULTS] We analysed 72 consecuti...
Aortic stenosis; Left atrial function; Relative apical longitudinal strain index; The peak longitudinal strain rate; Transthyretin amyloid cardiomyopathy; Two-dimensional speckle tracking echocardiography
0.899
57
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,338,035
Anifrolumab efficacy and safety by type I interferon gene signature and clinical subgroups in patients with SLE: post hoc analysis of pooled data from two phase III trials.
Annals of the rheumatic diseases
Ann Rheum Dis
81
7
10.1136/annrheumdis-2021-221425
eng
2,022
7
null
2,022
3
25
[OBJECTIVES] To characterise the efficacy and safety of anifrolumab in patients with systemic lupus erythematosus (SLE) according to interferon gene signature (IFNGS), demographic and clinical subgroups. [METHODS] We performed post hoc analyses of pooled data from the 52-week phase III TULIP-1/TULIP-2 placebo-controlle...
biological therapy; lupus erythematosus; systemic; therapeutics
6.489
300
Biochemistry, Genetics and Molecular Biology; Immunology; Immunology and Allergy; Rheumatology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
35,337,957
Anterolateral Structure Reconstructions With Different Tibial Attachment Sites Similarly Improve Tibiofemoral Kinematics and Result in Different Graft Force in Treating Knee Anterolateral Instability.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Arthroscopy
38
9
10.1016/j.arthro.2022.03.012
eng
2,022
9
null
2,022
3
22
[PURPOSE] To compare the biomechanical effects of anterolateral structure reconstructions (ALSRs) with different tibial attachments on tibiofemoral kinematics and anterolateral structure (ALS) graft forces. [METHODS] Eight cadaveric knees were tested in a customized knee testing system, using a novel pulley system to s...
null
null
null
null
null
null
35,337,853
The absence of cellular glucose triggers oncogene AEG-1 that instigates VEGFC in HCC: A possible genetic root cause of angiogenesis.
Gene
Gene
826
null
10.1016/j.gene.2022.146446
eng
2,022
6
5
2,022
3
22
[BACKGROUND AND OBJECTIVE] Astrocyte Elevated Gene-1 (AEG-1) is the master and multi-regulator of the various transcriptional factor primarily regulating chemoresistance, angiogenesis, metastasis, and invasion under the pathological condition, including liver cancer. This study was focused on investigating the process ...
2-deoxy-D-glucose; AEG-1; VEGFC and HCC
0.73
200
Genetics; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,337,613
Association between reproductive lifespan and risk of incident type 2 diabetes and hypertension in postmenopausal women: Findings from a 20-year prospective study.
Maturitas
Maturitas
159
null
10.1016/j.maturitas.2022.01.001
eng
2,022
5
null
2,022
1
11
[BACKGROUND] This study examined the association between reproductive lifespan and incident type 2 diabetes mellitus (T2DM) and hypertension in mid-age women. Also, the combined effect of reproductive lifespan and body mass index (BMI) on the risks of T2DM and hypertension were explored. [METHODS] Reproductive lifespan...
Hypertension; Menarche; Menopause; Reproductive lifespan; Type 2 diabetes
1.16
136
Biochemistry, Genetics and Molecular Biology; Obstetrics and Gynecology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,334,985
Humoral and Cellular Immune Responses of Solid Organ Transplant Patients on Belatacept to Three Doses of mRNA-Based Anti-SARS-CoV-2 Vaccine.
Vaccines
Vaccines (Basel)
10
3
10.3390/vaccines10030354
eng
2,022
2
24
2,022
2
24
[BACKGROUND] Two doses of anti-SARS-CoV-2 mRNA-based vaccines are poorly immunogenic in solid organ transplant recipients (SOT). [METHODS] In total, 68 belatacept-treated SOT recipients followed at the Toulouse University Hospital were investigated. They were given three injections of the BNT162b2 mRNA COVID-19 vaccine...
IgG SARS-CoV-2; anti-spike; solid organ transplant recipients
1.655
97
Drug Discovery; Immunology; Infectious Diseases; Pharmacology; Pharmacology
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,334,492
Biomarkers of connective tissue disease-associated interstitial lung disease in bronchoalveolar lavage fluid: A label-free mass spectrometry-based relative quantification study.
Journal of clinical laboratory analysis
J Clin Lab Anal
36
5
10.1002/jcla.24367
eng
2,022
5
null
2,022
3
25
[BACKGROUND] The pathogenesis of connective tissue disease-associated interstitial lung disease (CTD-ILD) is unclear. This study aims to identify differentially expressed proteins (DEPs) in CTD-ILD to determine the potential role of these DEPs that may play in the pathogenesis of CTD-ILD and to offer potential therapeu...
BALF; CTD-ILD; LC-MC/MS; pathogenesis; proteomics
0.594
67
Medical Laboratory Technology; Biochemistry; Clinical Biochemistry; Public Health, Environmental and Occupational Health; Hematology; Immunology and Allergy; Microbiology
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,022
35,333,186
Predicting Changes in Depression Severity Using the PSYCHE-D (Prediction of Severity Change-Depression) Model Involving Person-Generated Health Data: Longitudinal Case-Control Observational Study.
JMIR mHealth and uHealth
JMIR Mhealth Uhealth
10
3
10.2196/34148
eng
2,022
3
25
2,022
3
25
[BACKGROUND] In 2017, an estimated 17.3 million adults in the United States experienced at least one major depressive episode, with 35% of them not receiving any treatment. Underdiagnosis of depression has been attributed to many reasons, including stigma surrounding mental health, limited access to medical care, and b...
depression; machine learning; person-generated health data
1.513
107
Health Informatics
Medicine
2,022
35,332,840
BDNF blood levels after electroconvulsive therapy in patients with mood disorders: An updated systematic review and meta-analysis.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
World J Biol Psychiatry
24
1
10.1080/15622975.2022.2058083
eng
2,023
1
null
2,022
4
21
[OBJECTIVES] Studies have suggested Brain-Derived Neurotrophic Factors (BDNF) increase after electroconvulsive therapy (ECT) although they were methodologically limited and enrolled small sample sizes. We aimed at updating a systematic review and meta-analysis to explore BDNF changes after ECT for the treatment of depr...
Brain-derived neurotrophic factor; electroconvulsive therapy; meta-analysis; mood disorders; systematic review
1.153
88
Medicine; Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,023
35,332,405
Association of a miRNA-binding site polymorphism in IL-16 gene with disease risk and clinical characteristics of rheumatoid arthritis and systemic lupus erythematosus.
Clinical rheumatology
Clin Rheumatol
41
7
10.1007/s10067-022-06131-0
eng
2,022
7
null
2,022
3
24
[INTRODUCTION] /objectives. Single nucleotide polymorphisms (SNPs) located at the 3'-UTR region of the target genes of microRNAs (miRNAs) can dysregulate their expression via disrupting the binding site of miRNAs. Interleukin-16 (IL-16) is involved in the pathogenesis of rheumatoid arthritis (RA) and systemic lupus ery...
IL-16; MicroRNAs; Rheumatoid arthritis; Single nucleotide polymorphism; Systemic lupus erythematosus
0.864
104
Medicine; Rheumatology
Medicine
2,022
35,332,064
Analysis of adverse drug events as a way to improve cancer patient care.
European journal of hospital pharmacy : science and practice
Eur J Hosp Pharm
31
1
10.1136/ejhpharm-2021-003199
eng
2,023
12
27
2,023
12
27
[PURPOSE] To define the signals that a new artificial intelligence (AI) system must emit to improve adverse drug events (ADEs) management in oral antineoplastic agents (OAA). [METHODS] A multidisciplinary group of experts in patient safety was set up to define what signals the new AI system must emit to improve ADEs ma...
Antineoplastic agents; BIOTECHNOLOGY; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; Quality of Health Care; Safety
0.36
28
Pharmacy
Health Professions
2,023
35,332,022
Early Ultrasonic Monitoring of Brain Growth and Later Neurodevelopmental Outcome in Very Preterm Infants.
AJNR. American journal of neuroradiology
AJNR Am J Neuroradiol
43
4
10.3174/ajnr.A7456
eng
2,022
4
null
2,022
3
24
[BACKGROUND AND PURPOSE] In infants born very preterm, monitoring of early brain growth could contribute to prediction of later neurodevelopment. Therefore, our aim was to investigate associations between 2 early cranial ultrasound markers (corpus callosum-fastigium and corpus callosum length) and neurodevelopmental ou...
null
null
null
null
null
null
35,332,019
A New Frontier in Temporal Bone Imaging: Photon-Counting Detector CT Demonstrates Superior Visualization of Critical Anatomic Structures at Reduced Radiation Dose.
AJNR. American journal of neuroradiology
AJNR Am J Neuroradiol
43
4
10.3174/ajnr.A7452
eng
2,022
4
null
2,022
3
24
[BACKGROUND AND PURPOSE] Photon-counting detector CT is a new technology with a limiting spatial resolution of ≤150 μm. In vivo comparisons between photon-counting detector CT and conventional energy-integrating detector CT are needed to determine the clinical impact of photon counting-detector CT in temporal bone imag...
null
null
null
null
null
null
35,331,653
Intermetatarsal ligament section assisted with sonography for the percutaneous surgery of Morton's disease: Cadaveric study.
Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons
Foot Ankle Surg
28
7
10.1016/j.fas.2022.03.007
eng
2,022
10
null
2,022
3
17
[BACKGROUND] Surgical treatment of Morton's neuroma remains controversial. Several surgical techniques have been described including percutaneous transection of the deep metatarsal transverse ligament (DMTL). [PURPOSE] To evaluate the efficacy and safety of percutaneous release of the DMTL under ultrasound guidance for...
Deep transverse metatarsal ligament; Interdigital neuroma; Percutaneous; Ultrasound
1
56
Orthopedics and Sports Medicine
Medicine
2,022
35,331,639
Nurse, Parent, and Nurse Leader Perspective on Adoption of iPads for Pediatric Preoperative Anxiety Reduction.
Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
J Perianesth Nurs
37
3
10.1016/j.jopan.2021.09.005
eng
2,022
6
null
2,022
3
22
[PURPOSE] The purpose of this study was to examine the use of an iPad to facilitate distraction and reduce anxiety with preoperative pediatric patients. [DESIGN] The authors conducted a descriptive case study in a Pre-Anesthesia Surgical Suite. [METHODS] Nurses were trained on the use of the iPad, which came preloaded ...
Anxiety; Distraction therapy; Pediatric
0.343
41
Medical and Surgical Nursing
Nursing
2,022
35,331,581
COVID-19 and the HIV continuum in people living with HIV enrolled in Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO) cohorts.
Drug and alcohol dependence
Drug Alcohol Depend
241
null
10.1016/j.drugalcdep.2022.109355
eng
2,022
12
1
2,022
2
12
[BACKGROUND] The COVID-19 pandemic disrupted the normal delivery of HIV care, altered social support networks, and caused economic insecurity. People with HIV (PWH) are vulnerable to such disruptions, particularly if they have a history of substance use. We describe engagement in care and adherence to antiretroviral th...
Antidepressant therapy; Care cascade; Depression; Depressive symptoms; Viral non-suppression
1.562
193
Pharmacology; Pharmacology; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,331,327
Evaluation of the Conversations About Gambling Mental Health First Aid course: effects on knowledge, stigmatising attitudes, confidence and helping behaviour.
BMC psychology
BMC Psychol
10
1
10.1186/s40359-022-00785-w
eng
2,022
3
24
2,022
3
24
[BACKGROUND] The effects of problem gambling are wide-ranging, affecting many aspects of health and negatively impacting the person who gambles, their family and friends, and their community. People experiencing problem gambling have low rates of help-seeking and perceive many barriers to treatment, although evidence s...
Early intervention; Education; Mental health first aid; Problem gambling; Public intervention
0.906
49
Medicine; Psychology
Medicine; Psychology
2,022
35,331,321
Mutational analysis of compound heterozygous mutation p.Q6X/p.H232R in SRD5A2 causing 46,XY disorder of sex development.
Italian journal of pediatrics
Ital J Pediatr
48
1
10.1186/s13052-022-01243-4
eng
2,022
3
24
2,022
3
24
[BACKGROUND] Over 100 mutations in the SRD5A2 gene have been identified in subjects with 46,XY disorder of sex development (DSD). Exploration of SRD5A2 mutations and elucidation of the molecular mechanisms behind their effects should reveal the functions of the domains of the 5α-reductase 2 enzyme and identify the caus...
46,XY DSD; Dihydrotestosterone; SRD5A2; p.Q6X/p.H232R mutation
0.661
65
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,331,251
Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density Plasmodium falciparum infections during a controlled human malaria infection study in Equatorial Guinea.
Malaria journal
Malar J
21
1
10.1186/s12936-022-04103-y
eng
2,022
3
24
2,022
3
24
[BACKGROUND] Progress towards malaria elimination has stagnated, partly because infections persisting at low parasite densities comprise a large reservoir contributing to ongoing malaria transmission and are difficult to detect. This study compared the performance of an ultrasensitive rapid diagnostic test (uRDT) desig...
Controlled human malaria infection; Low parasite density infections; Malaria; Malaria pre-exposure; Rapid diagnostic test; Thick blood smear
1.237
126
Infectious Diseases; Parasitology
Immunology and Microbiology; Medicine
2,022
35,331,238
A multifunctional composite hydrogel as an intrinsic and extrinsic coregulator for enhanced therapeutic efficacy for psoriasis.
Journal of nanobiotechnology
J Nanobiotechnology
20
1
10.1186/s12951-022-01368-y
eng
2,022
3
24
2,022
3
24
[BACKGROUND] Psoriasis is a chronic relapsing immunological skin disease characterized by multiple cross-talk inflammatory circuits which are relevantly associated with abnormal cross-reactivity between immune cells and keratinocytes (KCs). It may be inadequate to eradicate complicated pathogenesis only via single-mode...
Hydrogel; Immunoregulation; Methotrexate; Psoriasis; Transdermal delivery
1.421
125
Applied Microbiology and Biotechnology; Bioengineering; Biomedical Engineering; Medicine; Molecular Medicine; Nanoscience and Nanotechnology; Pharmaceutical Science
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Immunology and Microbiology; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,331,226
The process of learning the autogenic training relaxation technique and its benefits on the wellness of people living with HIV.
BMC complementary medicine and therapies
BMC Complement Med Ther
22
1
10.1186/s12906-022-03557-6
eng
2,022
3
24
2,022
3
24
[BACKGROUND] Various mind-body practices are used by people living with HIV to promote their general well-being. Among these is autogenic training (AT), a self-guided relaxation technique requiring regular practice for observable benefits. However, little has been written about the process of learning this technique, w...
Autogenic training; HIV; Learning process; Mind-body; Wellness
0.688
123
Complementary and Alternative Medicine
Medicine
2,022
35,331,203
One year monitoring of SARS-CoV-2 prevalence in a German cohort of patients with cystic fibrosis.
BMC pulmonary medicine
BMC Pulm Med
22
1
10.1186/s12890-022-01900-8
eng
2,022
3
24
2,022
3
24
[BACKGROUND] In Germany, the first case of coronavirus disease 2019 (COVID-19) was registered on 28 January 2020. By February 2021, the third wave of the pandemic began. So far, only few data are available on the SARS-CoV-2 prevalence and the clinical impact of an infection in patients with cystic fibrosis (CF). [METHO...
null
0.999
85
Pulmonary and Respiratory Medicine
Medicine
2,022
35,331,152
Real-time ultrasound-guided stellate ganglion block for migraine: an observational study.
BMC anesthesiology
BMC Anesthesiol
22
1
10.1186/s12871-022-01622-8
eng
2,022
3
24
2,022
3
24
[OBJECTIVE] To observe whether ultrasound-guided stellate ganglion block (SGB) can effectively relieve migraine pain and improve the quality of migraine patients' life. [METHODS] 81 patients with migraines were enrolled in this study. The patients received SGB with 6 ml of 0.15% ropivacaine once every week for four tim...
Migraine; Stellate ganglion block (SGB); Ultrasound guidance
0.609
58
Anesthesiology and Pain Medicine
Medicine
2,022
35,331,107
Evaluating Potentials of Species Rich Taxonomic Groups in Cosmetics and Dermatology: Clustering and Dispersion of Skin Efficacy of Asteraceae and Ranunculales Plants on the Species Phylogenetic Tree.
Current pharmaceutical biotechnology
Curr Pharm Biotechnol
24
2
10.2174/1389201023666220324123926
eng
2,023
null
null
null
null
null
[BACKGROUND] The medicinal properties of plants can be predicted by virtue of phylogenetic methods, which nevertheless have not been utilized to explore the regularity of skin-related bioactivities of ethnomedicinal plants. We aim to investigate the distribution of skin efficacy of Asteraceae and Ranunculales plants on...
Dstatistic; Ranunculales; asteraceae; nearest taxon index; net relatedness index; phylogenetic diversity; skin efficacy
null
null
null
null
null
35,330,589
Photodynamic therapy for treatment of recurrent adenocarcinoma of the lung with tracheal oligometastasis.
Respiratory medicine case reports
Respir Med Case Rep
37
null
10.1016/j.rmcr.2022.101620
eng
2,022
null
null
2,022
3
10
[INTRODUCTION] Tracheal neoplasms account for less than 0.1% of all malignancies. The majority of tracheal malignancies are secondary neoplasms from direct tracheal invasion from adjacent structures and less commonly from hematogenous or lymphatic spread from distal malignancies. Evidence-based guidelines for managemen...
Bronchoscopic ablation; Photodynamic therapy; Tracheal adenocarcinoma; Tracheobronchial malignancies
null
null
null
null
null
35,330,337
Ultrasonographic Confirmation of Nasogastric Tube Placement in the COVID-19 Era.
Journal of personalized medicine
J Pers Med
12
3
10.3390/jpm12030337
eng
2,022
2
23
2,022
2
23
[BACKGROUND] Nasogastric tube (NGT) placement is a daily routine in the Intensive Care Unit (ICU), and misplacement of the NGT can cause serious complications. In COVID-19 ARDS patients, proning has emerged the need for frequent NGT re-evaluations. The gold standard technique, chest X-ray, is not always feasible. In th...
POCUS; intensive care unit; nasogastric tube; ultrasonography
0.665
62
Medicine
Medicine
2,022
35,330,328
A Machine Learning Approach to Predict the Rehabilitation Outcome in Convalescent COVID-19 Patients.
Journal of personalized medicine
J Pers Med
12
3
10.3390/jpm12030328
eng
2,022
2
22
2,022
2
22
[BACKGROUND] After the acute disease, convalescent coronavirus disease 2019 (COVID-19) patients may experience several persistent manifestations that require multidisciplinary pulmonary rehabilitation (PR). By using a machine learning (ML) approach, we aimed to evaluate the clinical characteristics predicting the effec...
COVID-19; chronic disease; disability; exercise; machine learning; occupational medicine; outcome; rehabilitation
0.665
62
Medicine
Medicine
2,022
35,329,998
Does Repeated Dosing of Intravenous Ferric Carboxymaltose Alleviate Symptoms of Restless Legs Syndrome?
Journal of clinical medicine
J Clin Med
11
6
10.3390/jcm11061673
eng
2,022
3
17
2,022
3
17
[BACKGROUND] Several studies have reported the efficacy of intravenous (IV) iron for patients with restless legs syndrome (RLS), but little is known about the efficacy or safety of repeated IV iron treatment. The aim of this study was to evaluate the effectiveness of repeated doses of IV ferric carboxymaltose (FCM) in ...
RLS; ferric carboxymaltose; intravenous; iron
0.935
132
Medicine
Medicine
2,022
35,329,336
The Relationship between Alexithymia and Mental Health Is Fully Mediated by Anxiety and Depression in Patients with Psoriasis.
International journal of environmental research and public health
Int J Environ Res Public Health
19
6
10.3390/ijerph19063649
eng
2,022
3
19
2,022
3
19
[BACKGROUND] Psoriasis is a common skin disease that affects quality of life, especially mental health. Alexithymia has been considered a relevant feature in psoriasis patients. Moreover, psoriasis was found to be associated with negative psychological health, including anxiety and depression. As the pathways linking a...
dermatology; mediation model; psychological distress; quality of life
0.828
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,022
35,325,358
Development of molecular markers based on CRa gene sequencing of different clubroot disease-resistant cultivars of Chinese cabbage.
Molecular biology reports
Mol Biol Rep
49
7
10.1007/s11033-022-07379-0
eng
2,022
7
null
2,022
3
23
[BACKGROUND] CRa is a key gene in Chinese cabbage (Brassica rapa ssp. pekinensis) that confers resistance to Plasmodiophora brassicae. In order to efficiently screen the clubroot resistance (CR) gene CRa in breeding, two functional codominant markers of the CRa gene were developed. [METHODS AND RESULTS] In this study, ...
CRa gene; Chinese cabbage; Clubroot; Molecular marker
0.578
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,325,347
Assessing the Impact of Primary Tumour Location on Survival After Resection of Colorectal Liver Metastases: A Propensity Weighted Retrospective Cohort Study.
World journal of surgery
World J Surg
46
7
10.1007/s00268-022-06514-z
eng
2,022
7
null
2,022
3
24
[BACKGROUND] Right-sided colonic tumours appear to have poorer survival after resection of colorectal liver metastases, although this may be confounded by various factors including advanced stage and emergency presentation. [METHODS] Medical records of consecutive patients undergoing resection of colorectal liver metas...
null
0.902
176
Surgery
Medicine
2,022
35,325,287
Predictive factors for postoperative visual acuity improvement with ICL-V4c for ultrahigh myopia above - 10 D.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Graefes Arch Clin Exp Ophthalmol
260
9
10.1007/s00417-022-05626-5
eng
2,022
9
null
2,022
3
24
[PURPOSE] The purpose of this study is to evaluate the predictive factors for postoperative visual acuity improvement (PVAI) in subjects who underwent phakic intraocular lens implantation with a central hole (ICL-V4c) for ultrahigh myopia above - 10 D. [METHODS] This was a retrospective study. Eyes with ultrahigh myopi...
ICL-V4c; Implantable Collamer lens; Myopic maculopathy; Ultrahigh myopia; Visual quality
null
null
null
null
null
35,325,098
Adjuvant chemotherapy for visceral pleural invasion in 3-4-cm non-small-cell lung cancer improves survival.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Eur J Cardiothorac Surg
62
1
10.1093/ejcts/ezab498
eng
2,022
6
15
null
null
null
[OBJECTIVES] Visceral pleural invasion (VPI) guidelines, for tumours ≤4 cm are ambiguous. Non-small-cell lung cancers (NSCLCs) 3 to ≤4 cm are assigned the T2a designation. Similarly, any tumours with VPI, smaller than 3 cm, are upstaged and also assigned the same T2a designation. We hypothesized that adjuvant chemother...
Adjuvant chemotherapy; Non-small-cell lung cancer; Stage I; Surgery; Visceral pleural invasion
1.183
158
Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,022
35,324,973
Better survival of patients with hepatitis B virus-related hepatocellular carcinoma in South Korea: Changes in 16-years cohorts.
PloS one
PLoS One
17
3
10.1371/journal.pone.0265668
eng
2,022
null
null
2,022
3
24
[AIMS] The incidence and mortality of hepatocellular carcinoma (HCC) have decreased over time in South Korea, where hepatitis B virus (HBV) in endemic. This study investigated the changes in the characteristics and clinical outcomes of HCC patients in Korea. [METHODS] Patients initially diagnosed with HCC and treated a...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,324,965
Association of maternal heavy metal exposure during pregnancy with isolated cleft lip and palate in offspring: Japan Environment and Children's Study (JECS) cohort study.
PloS one
PLoS One
17
3
10.1371/journal.pone.0265648
eng
2,022
null
null
2,022
3
24
[BACKGROUND] Cleft lip and palate (cleft L/P) is one of the most common congenital anomalies and its etiology is assumed to be multifactorial. Recent epidemiological data involving a small number of participants suggested an association between perinatal exposure to heavy metals and cleft L/P in affected children. Howe...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,324,491
Cultural Humility Toolkit.
Nurse educator
Nurse Educ
47
5
10.1097/NNE.0000000000001182
eng
null
null
null
2,022
3
25
[BACKGROUND] Diversity, equity, and inclusion (DEI) are increasingly recognized as core values for nursing education and practice. [PURPOSE] The purpose of this article is to offer teaching tools and strategies to integrate cultural humility within the nursing curriculum and create a more inclusive learning environment...
null
null
null
null
null
null
35,323,950
Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19.
JAMA network open
JAMA Netw Open
5
3
10.1001/jamanetworkopen.2022.3890
eng
2,022
3
1
2,022
3
1
[IMPORTANCE] Prior observational studies suggest that aspirin use may be associated with reduced mortality in high-risk hospitalized patients with COVID-19, but aspirin's efficacy in patients with moderate COVID-19 is not well studied. [OBJECTIVE] To assess whether early aspirin use is associated with lower odds of in-...
null
4.108
154
Medicine
Medicine
2,022
35,323,718
Novel Psychoactive Substances: The Razor's Edge between Therapeutical Potential and Psychoactive Recreational Misuse.
Medicines (Basel, Switzerland)
Medicines (Basel)
9
3
10.3390/medicines9030019
eng
2,022
3
1
2,022
3
1
[BACKGROUND] Novel psychoactive substances (NPS) are compounds of natural and synthetic origin, similar to traditional drugs of abuse. NPS are involved in a contemporary trend whose origin lies in a thinner balance between legitimate therapeutic drug research and legislative control. The contemporary NPS trend resulted...
NPS; synthetic cannabinoids; synthetic cathinones; therapeutic; toxicology
null
null
null
null
null
35,322,968
Comparison of Clinical Efficacy of Epidural Injection With or Without Steroids in the Treatment of Degenerative Disc Disease: Meta-analysis.
Pain physician
Pain Physician
25
2
null
eng
2,022
3
null
null
null
null
[BACKGROUND] Selective nerve root block has been widely used to treat degenerative disc disease (DDD), but no detailed research data is provided to compare the efficacy of epidural injection of anesthetics with or without steroids on the DDD treatment. [OBJECTIVES] This study aimed to  provide the first comparison of s...
degenerative disc disease; epidural injection; local anesthetics; meta-analysis; Steroids
null
null
null
null
null
35,322,778
Risk and economic burden of surgical site infection following spinal fusion in adults.
Infection control and hospital epidemiology
Infect Control Hosp Epidemiol
44
1
10.1017/ice.2022.32
eng
2,023
1
null
2,022
3
24
[BACKGROUND] Spinal fusion surgery (SFS) is one of the most common operations in the United States, >450,000 SFSs are performed annually, incurring annual costs >$10 billion. [OBJECTIVES] We used a nationwide longitudinal database to accurately assess incidence and payments associated with management of postoperative i...
null
1.117
156
Infectious Diseases; Microbiology; Epidemiology
Medicine
2,023
35,322,698
Single-dose premedication enhances multimodal analgesia after knee arthroplasty.
Journal of perioperative practice
J Perioper Pract
33
6
10.1177/17504589211049292
eng
2,023
6
null
2,022
3
24
[BACKGROUND] With the current trend to reduce postoperative opioid use to enhance recovery and address perioperative opioid addiction concerns, the challenge of managing pain after total knee arthroplasty has increased. This study examined the effect of adding a preoperative medication regime to a multimodal postoperat...
null
null
null
null
null
null
35,321,956
Clinical Features and Long-term Prognosis of Crohn's Disease in Korea: Results from the Prospective CONNECT Study.
Gut and liver
Gut Liver
16
6
10.5009/gnl210299
eng
2,022
11
15
2,022
3
24
[BACKGROUND/AIMS] The prospective Crohn's Disease Clinical Network and Cohort Study is a nationwide multicenter cohort study of patients with Crohn's disease (CD) in Korea, aiming to prospectively investigate the clinical features and long-term prognosis associated with CD. [METHODS] Patients diagnosed with CD between ...
Cohort studies; Crohn disease; Korea; Multicenter study; Prognosis
1.057
67
Gastroenterology; Hepatology
Medicine
2,022
35,321,729
Lung transplantation with concomitant cardiac repair for congenital hypoplasia of bilateral pulmonary arteries and patent ductus arteriosus.
Journal of cardiothoracic surgery
J Cardiothorac Surg
17
1
10.1186/s13019-022-01792-z
eng
2,022
3
23
2,022
3
23
[BACKGROUND] Profound pulmonary arterial hypertension with end-stage right heart failure is considered to be the main cause of death in children with un-repaired congenital heart disease, and the traditional surgical treatment is heart-lung transplantation. We performed bilateral lung transplantation (LTx) with concomi...
Congenital heart disease; Lung transplantation; Patent ductus arteriosus
0.451
61
Surgery; Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
35,321,715
Menstrual hygiene management practice among adolescent girls: an urban-rural comparative study in Rajshahi division, Bangladesh.
BMC women's health
BMC Womens Health
22
1
10.1186/s12905-022-01665-6
eng
2,022
3
23
2,022
3
23
[INTRODUCTION] Adolescence is a critical period characterized by significant physical, emotional, cognitive, and social changes, including the monthly occurrence of menstruation of adolescent girls. Despite being an inevitable natural event, most societies consider menstruation and menstrual blood as taboos and impure....
Adolescent girls; Bangladesh; Menstrual hygiene; Menstrual hygiene management practice
0.775
73
Medicine; Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,022
35,321,536
Health-Related Quality of Life Assessment in Daily Urologic Practice: A Survey of Greek Urologists.
Research and reports in urology
Res Rep Urol
14
null
10.2147/RRU.S354925
eng
2,022
null
null
2,022
3
17
[PURPOSE] Health-related quality of life (HRQoL) assessment has become an integral part of clinical research across different disciplines. However, the degree of incorporation of QoL standardized questionnaires in daily routine is variable. This survey study examined how HRQoL is perceived and utilized among urologists...
health-related quality of life assessment; questionnaire; survey; urologic daily practice
0.417
32
Urology
Medicine
2,022
35,321,353
Association Between Elevated Thyroid Peroxidase Antibody and Abdominal Fat Distribution in Patients with Type 2 Diabetes Mellitus.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
15
null
10.2147/DMSO.S345507
eng
2,022
null
null
2,022
3
17
[OBJECTIVE] Obesity and autoimmune thyroid disease (AITD) are both common disorders in the general population, which are major drivers for adverse medical conditions. While an interaction between thyroid function and visceral obesity is thought to exist, but very few studies have examined the relationship between AITD ...
autoimmune thyroid disease; thyroid peroxidase antibody; type 2 diabetes mellitus; visceral obesity
0.851
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,320,899
Association between Complementary and Alternative Medicine Use and Fear of Cancer Recurrence among Breast Cancer Survivors.
Korean journal of family medicine
Korean J Fam Med
43
2
10.4082/kjfm.20.0158
eng
2,022
3
null
2,022
3
17
[BACKGROUND] This study aimed to evaluate the association between complementary and alternative medicine (CAM) use and fear of cancer recurrence (FCR) among breast cancer survivors, using a validated multidimensional FCR-assessing instrument. Despite the debate over its medical effects, the use of CAM in breast cancer ...
Alternative Medicine; Breast Neoplasms; Cancer Survivors; Complementary Medicine; Fear of Cancer Recurrence; Fear of Cancer Recurrence Inventory
0.459
32
Family Practice
Medicine
2,022
35,320,827
The RNA-binding protein SND1 promotes the degradation of GPX4 by destabilizing the HSPA5 mRNA and suppressing HSPA5 expression, promoting ferroptosis in osteoarthritis chondrocytes.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Inflamm Res
71
4
10.1007/s00011-022-01547-5
eng
2,022
4
null
2,022
3
23
[BACKGROUND] Heat shock protein family A member 5 (HSPA5), a recently identified suppressor of ferroptosis, was reported to potentially regulating osteoarthritis. However, the exact role of HSPA5 and how its expression was regulated in osteoarthritis are largely unclear. [METHODS] Rat primary chondrocytes were treated ...
Chondrocyte; Ferroptosis; GPX4; HSPA5; Osteoarthritis; SND1
1.339
112
Pharmacology; Immunology
Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics
2,022
35,320,764
Exploring the use of enhanced cone-beam CT technique to diagnose vertical root fracture.
Journal of the mechanical behavior of biomedical materials
J Mech Behav Biomed Mater
130
null
10.1016/j.jmbbm.2022.105175
eng
2,022
6
null
2,022
3
18
[OBJECTIVES] To explore the feasibility of using sodium iodide (NaI)+dimethyl sulfoxide (DMSO)+ethyl alcohol+ethyl acetate as a cone-beam CT (CBCT) contrast agent in the diagnosis of vertical root fracture (VRF). [METHODS] 21 endodontically treated VRF teeth of 21 patients were collected in this study. All these 21 tee...
Cone-beam CT; Contrast agent; Dimethyl sulfoxide; Ethyl acetate; Ethyl alcohol; Sodium iodide; Vertical root fracture
0.725
130
Biomaterials; Biomedical Engineering; Mechanics of Materials
Engineering; Materials Science
2,022
35,320,762
Knowledge about atrial fibrillation and anticoagulation affects the risk of clinical outcomes.
Thrombosis research
Thromb Res
213
null
10.1016/j.thromres.2022.03.011
eng
2,022
5
null
2,022
3
15
[BACKGROUND] Knowledge about atrial fibrillation (AF) and oral anticoagulation (OAC) is insufficient among AF patients. [OBJECTIVE] We examined the association between this knowledge and event rate. [METHODS] We studied 174 anticoagulated patients with AF aged 69±10.7 years (median CHA2DS2 -VASc 4). Knowledge was asses...
Anticoagulation; Atrial fibrillation; Bleeding
1.487
134
Hematology
Medicine
2,022
35,320,487
Association of androgenetic alopecia with a more severe form of COVID-19 infection.
Irish journal of medical science
Ir J Med Sci
192
1
10.1007/s11845-022-02981-4
eng
2,023
2
null
2,022
3
23
[BACKGROUND] Individual susceptibility to develop acute respiratory distress syndrome is related to age and most frequent comorbidities. So far, it is known that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily infects the type II pneumocytes in humans, with the help of transmembrane serine protea...
Androgen receptors; Androgenetic alopecia; Gabrin sign; SARS-CoV-2; Transmembrane serine protease 2
0.532
46
Medicine
Medicine
2,023
35,320,383
Clinical performance of resin-matrix ceramic partial coverage restorations: a systematic review.
Clinical oral investigations
Clin Oral Investig
26
5
10.1007/s00784-022-04449-2
eng
2,022
5
null
2,022
3
23
[OBJECTIVE] To evaluate clinical performance of the new CAD/CAM resin-matrix ceramics and compare it with ceramic partial coverage restorations. [MATERIALS AND METHODS] An electronic search of 3 databases (The National Library of Medicine (MEDLINE/PubMed), Scopus, and the Cochrane Central Register of Controlled Trials)...
CAD/CAM; Ceramics; Hybrid ceramics; Indirect restorations; Resin-matrix ceramics
0.91
108
Dentistry
Dentistry
2,022
35,320,169
Social appearance anxiety, emotional regulation and quality of life in individuals with premature canities: A correlational study.
JPMA. The Journal of the Pakistan Medical Association
J Pak Med Assoc
72
2
10.47391/JPMA.178
eng
2,022
2
null
null
null
null
[OBJECTIVE] To examine and predict the relationship among social appearance anxiety, emotional regulation and quality of life in individuals with premature canities. [METHODS] The correlational study was conducted from September 2019 to February 2020 in Lahore, Pakistan, after approval from the Riphah International Uni...
null
null
null
null
null
null
35,320,142
OCT-Angiography Face Mask-Associated Artifacts During the COVID-19 Pandemic.
Journal of glaucoma
J Glaucoma
31
6
10.1097/IJG.0000000000002019
eng
2,022
6
1
2,022
3
23
[PRCIS] Face mask wearing has no significant effects on artifacts or vessel density measurements in optic nerve head (ONH) and macular optical coherence tomography-angiography (OCT-A) scans. [PURPOSE] The aim was to assess the difference in area of artifacts observed in optical OCT-A scans with and without face mask we...
null
0.897
105
Ophthalmology
Medicine
2,022
35,319,855
Seasonality of Pediatric Mental Health Emergency Department Visits, School, and COVID-19.
Pediatric emergency care
Pediatr Emerg Care
38
12
10.1097/PEC.0000000000002671
eng
2,022
12
1
2,022
2
23
[OBJECTIVES] The aim of this study was to explore how the academic calendar, and by extension school-year stressors, contributes to the seasonality of pediatric mental health emergency department (ED) visits. [METHODS] The authors reviewed all pediatric mental health ED visits at a large urban medical center from 2014 ...
null
0.404
79
Emergency Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
35,319,853
Ventilatory performance of BASKA mask as an alternative to endotracheal intubation in short-term gynecologic laparoscopic procedures: a prospective randomized clinical trial.
Minerva anestesiologica
Minerva Anestesiol
88
12
10.23736/S0375-9393.22.16492-8
eng
2,022
12
null
2,022
3
23
[BACKGROUND] Using laryngeal mask airways (LMAs) in laparoscopic surgery is still controversial because of the risk of insufficient ventilation and gastric overinflation. We investigated the use of BASKA LMA as an alternative to endotracheal intubation in low-risk females undergoing short-term gynecologic laparoscopic ...
null
0.668
73
Anesthesiology and Pain Medicine
Medicine
2,022
35,319,725
Improving Enrollment of Underrepresented Racial and Ethnic Populations in Heart Failure Trials: A Call to Action From the Heart Failure Collaboratory.
JAMA cardiology
JAMA Cardiol
7
5
10.1001/jamacardio.2022.0161
eng
2,022
5
1
null
null
null
[IMPORTANCE] Despite bearing a disproportionate burden of heart failure (HF), Black and Hispanic individuals have been poorly represented in HF clinical trials. Underrepresentation in clinical trials limits the generalizability of the findings to these populations and may even introduce uncertainties and hesitancy when...
null
7.371
127
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,319,402
Nicorandil and Bone Marrow-derived Mesenchymal Stem Cells Therapeutic Effect after Ureteral Obstruction in Adult Male Albino Rats.
Current molecular pharmacology
Curr Mol Pharmacol
16
1
10.2174/1874467215666220322113734
eng
2,023
null
null
null
null
null
[BACKGROUND] Chronic kidney disease is a global health problem for which renal fibrogenesis is the final treatment target. [OBJECTIVE] In our work, we have highlighted two new strategies, nicorandil and Bone marrow-derived mesenchymal stem cells (BM-MSCs), as effective in reversing renal fibrosis induced by partial uni...
BM-MSCs; TNF; nicrorandil; renal fibrosis; ureteral obstruction
null
null
null
null
null
35,319,386
FDG-PET/CT Assessment of the Cerebral Protective Effects of Hydrogen in Rabbits with Cardiac Arrest.
Current medical imaging
Curr Med Imaging
18
9
10.2174/1573405618666220321122214
eng
2,022
null
null
null
null
null
[BACKGROUND] Anatomical imaging methods and histological examinations have limited clinical value for early monitoring of brain function damage after cardiac arrest (CA) in vivo. [OBJECTIVE] We aimed to assess the cerebral protective effects of hydrogen in rabbits with CA by using fluorodeoxyglucose-positron emission t...
Cardiopulmonary resuscitation; FDG-PET/CT; NSE; UCH-L1; brain protection; hydrogen
0.263
27
Internal Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,319,139
Centre-based comparison of double versus single prevention strategy on transfusion-transmitted cytomegalovirus in at-risk haemopoietic stem cell transplant patients and a state survey on cytomegalovirus-seronegative ordering practises.
Internal medicine journal
Intern Med J
53
5
10.1111/imj.15751
eng
2,023
5
null
2,022
9
2
[BACKGROUND] Universal leucocyte depletion reduces the risk of transfusion-transmitted cytomegalovirus; however, many clinicians still prescribe cytomegalovirus seronegative units. [AIM] Our retrospective study aims to confirm the low risk of transfusion-transmitted cytomegalovirus with leucocyte depletion alone and de...
cytomegalovirus; haemopoietic stem cell transplant; leucocyte depletion; transfusion
0.585
85
Internal Medicine
Medicine
2,023
35,318,872
Public acceptability of COVID-19 vaccines and its predictors in Middle ‎Eastern/North African (MENA) countries: a systematic review‎.
Human vaccines immunotherapeutics
Hum Vaccin Immunother
18
5
10.1080/21645515.2022.2043719
eng
2,022
11
30
2,022
3
23
[INTRODUCTION] COVID-19 vaccines emerged as a worldwide hope to contain the pandemic. However, many people ‎are still hesitant to receive these vaccines. We aimed to systematically review the public knowledge, perception, and acceptability of COVID-19 vaccines in the Middle East and North Africa (MENA) countries and th...
Attitude; COVID-19; COVID-19 vaccine; Middle East; North Africa; SARS-CoV-2; acceptability; perception; vaccine
null
null
null
null
null
35,318,645
Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations.
British journal of pharmacology
Br J Pharmacol
179
15
10.1111/bph.15841
eng
2,022
8
null
2,022
4
8
[BACKGROUND AND PURPOSE] N-methyl-D-aspartate receptors (NMDARs) play a critical role in synaptic plasticity, and mutations in human genes encoding NMDAR subunits have been described in individuals with various neuropsychiatric disorders. Compounds with a positive allosteric effect are thought to compensate for reduced...
GRIN channelopathy; NMDA receptor; positive allosteric modulator; steroids; transmembrane domain
2.019
252
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,022
35,318,491
Estrogenic impregnation alters pain expression: analysis through functional neuropeptidomics in a surgical rat model of osteoarthritis.
Naunyn-Schmiedeberg's archives of pharmacology
Naunyn Schmiedebergs Arch Pharmacol
395
6
10.1007/s00210-022-02231-5
eng
2,022
6
null
2,022
3
23
[PURPOSE] Several observational studies suggest that estrogens could bias pain perception. To evaluate the influence of estrogenic impregnation on pain expression, a prospective, randomized, controlled, blinded study was conducted in a Sprague-Dawley rat model of surgically induced osteoarthritis (OA). [METHODS] Female...
Animal model; Cartilage; Neuropeptide; Osteoarthritis
0.66
101
Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,317,323
Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways.
World journal of gastrointestinal oncology
World J Gastrointest Oncol
14
2
10.4251/wjgo.v14.i2.450
eng
2,022
2
15
null
null
null
[BACKGROUND] In traditional Chinese medicine (TCM), frankincense and myrrh are the main components of the antitumor drug Xihuang Pill. These compounds show anticancer activity in other biological systems. However, whether frankincense and/or myrrh can inhibit the occurrence of hepatocellular carcinoma (HCC) is unknown,...
Frankincense; Hepatocellular carcinoma; Multiple signaling pathways; Myrrh; Network pharmacology; Tumor blood vessels
null
null
null
null
null
35,317,301
Bond strength and internal adaptation of customized glass fiber posts using different bulk-fill flow resins.
Journal of clinical and experimental dentistry
J Clin Exp Dent
14
3
10.4317/jced.57683
eng
2,022
3
null
2,022
3
1
[BACKGROUND] This study aimed to evaluate the bond strength and internal adaptation of customized glass fiber posts using Bulk Fill flowable composite resins (BF) and conventional composite resin. [MATERIAL AND METHODS] Fifty bovine teeth were randomly divided (n=10) according to the following groups: G1 (control): gla...
null
0.445
44
Dentistry
Dentistry
2,022
35,317,250
Comparative study of intertrochanteric fracture fixation using proximal femoral nail with and without distal interlocking screws.
World journal of orthopedics
World J Orthop
13
3
10.5312/wjo.v13.i3.267
eng
2,022
3
18
2,022
3
18
[BACKGROUND] Intertrochanteric (IT) fracture is one of the most common fractures seen in an orthopaedic practice. Proximal femoral nailing (PFN) is a common modality of fixing IT femur fracture. We retrospectively studied whether a PFN with two proximal lag screws can be done without distal interlocking screws in the 3...
Distal interlocking screws; Intertrochanteric fracture; Outcome; Proximal femoral nail; Without distal interlocking screws
0.533
64
Orthopedics and Sports Medicine
Medicine
2,022
35,317,148
Eosinophilia complicated with venous thromboembolism: A case report.
World journal of clinical cases
World J Clin Cases
10
6
10.12998/wjcc.v10.i6.1952
eng
2,022
2
26
null
null
null
[BACKGROUND] Eosinophilia is an increase of more than 0.5 × 10[9]/L in the number of eosinophils; it is a systemic condition with an unknown etiology and is often accompanied by multiple impaired organ functions. The clinical manifestations of the disease are highly variable and diverse, rendering identification of the...
Case report; Diagnosis; Eosinophilia; Management; Venous thromboembolism; Venous thrombosis
null
38
Medicine
Medicine
2,022
35,317,096
Treatment strategy for pancreatic head cancer with celiac axis stenosis in pancreaticoduodenectomy: A case report and review of literature.
World journal of gastroenterology
World J Gastroenterol
28
8
10.3748/wjg.v28.i8.868
eng
2,022
2
28
null
null
null
[BACKGROUND] During pancreaticoduodenectomy in patients with celiac axis (CA) stenosis due to compression by the median arcuate ligament (MAL), the MAL has to be divided to maintain hepatic blood flow in many cases. However, MAL division often fails, and success can only be determined intraoperatively. To overcome this...
Case report; Celiac axis stenosis; Endovascular stenting; Median arcuate ligament; Pancreatic head cancer; Pancreaticoduodenectomy
null
null
null
null
null
35,316,725
Lactate metabolism in rheumatoid arthritis: Pathogenic mechanisms and therapeutic intervention with natural compounds.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine
100
null
10.1016/j.phymed.2022.154048
eng
2,022
6
null
2,022
3
15
[BACKGROUND] Rheumatoid arthritis (RA) is a common chronic and systemic autoimmune disease characterized by persistent inflammation and hyperplasia of the synovial membrane, the degradation of cartilage, and the erosion of bones in diarthrodial joints. The inflamed joints of patients with RA have been recognized to be ...
Hypoxic microenvironment; Lactate metabolism; Natural compounds; Rheumatoid arthritis; Synovial fibroblasts
1.126
150
Complementary and Alternative Medicine; Drug Discovery; Pharmaceutical Science; Pharmacology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,316,570
Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID-19, not entirely explaining the increased risk of thrombosis.
Journal of thrombosis and haemostasis : JTH
J Thromb Haemost
20
6
10.1111/jth.15708
eng
2,022
6
null
2,022
4
1
[BACKGROUND] Severe acute respiratory syndrome coronavirus 2 infection is associated with an increased incidence of thrombosis. [OBJECTIVES] By studying the fibrin network structure of coronavirus disease 2019 (COVID-19) patients, we aimed to unravel pathophysiological mechanisms that contribute to this increased risk ...
COVID-19; fibrin; fibrinolysis; microscopy; thrombosis
3.086
217
Hematology; Medicine
Medicine
2,022
35,316,404
Predictive value of preoperative handgrip strength on postoperative outcomes in patients with gastrointestinal tumors: a systematic review and meta-analysis.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
30
8
10.1007/s00520-022-06983-x
eng
2,022
8
null
2,022
3
22
[PURPOSE] This systematic review and meta-analysis aimed to explore the predictive value of preoperative handgrip strength on postoperative outcomes in patients with gastrointestinal tumors. [METHODS] Databases including Cochrane Library, Pubmed, Embase, Web of Science, and CINAHL Complete were searched for articles pu...
Digestive carcinoma; Handgrip strength; Postoperative outcomes; Surgery
0.984
143
Oncology
Medicine
2,022
35,315,963
Mental health prior to and during the COVID-19 pandemic in individuals with bipolar disorder: Insights from prospective longitudinal data.
Bipolar disorders
Bipolar Disord
24
6
10.1111/bdi.13204
eng
2,022
9
null
2,022
3
28
[OBJECTIVES] Many studies have examined the impact of COVID-19 on the mental health of the public, but few have focused on individuals with existing severe mental illness with longitudinal data before and during the pandemic. [AIMS] To investigate the impact of the COVID-19 pandemic on the mental health of people with ...
COVID-19; bipolar disorder; depression; longitudinal; mania
1.7
145
Biological Psychiatry; Psychiatry and Mental Health
Medicine; Neuroscience
2,022
35,315,627
Short-term perioperative cognitive therapy combined with rehabilitation exercise reduces the incidence of neurocognitive disorder in elderly patients: a randomized controlled trial.
Minerva anestesiologica
Minerva Anestesiol
88
3
10.23736/S0375-9393.21.15877-8
eng
2,022
3
null
null
null
null
[BACKGROUND] To investigate whether short-term perioperative cognitive therapy combined with rehabilitation exercise decreases the incidence of neurocognitive disorder (NCD) in elderly patients who have undergone hip joint replacement surgery. This was a randomized, parallel controlled trial on elderly patients who und...
null
0.668
73
Anesthesiology and Pain Medicine
Medicine
2,022
35,315,156
Acetylsalicylic acid use is associated with improved survival in bacteremic pneumococcal pneumonia: A long-term nationwide study.
Journal of internal medicine
J Intern Med
292
2
10.1111/joim.13485
eng
2,022
8
null
2,022
3
30
[BACKGROUND] Pneumonia is commonly caused by Streptococcus pneumoniae (pneumococcus) and associated with subsequent cardiovascular complications and increased mortality. Potential short-term survival benefits conferred by acetylsalicylic acid (ASA) use in pneumonia remain controversial, and long-term outcomes have not ...
Streptococcus pneumoniae; aspirin; pneumonia; population-based; survival
2.992
195
Internal Medicine
Medicine
2,022
35,315,066
Postural control impairment in patients with headaches-A systematic review and meta-analysis.
Headache
Headache
62
3
10.1111/head.14281
eng
2,022
3
null
null
null
null
[OBJECTIVE] To summarize the evidence regarding static and dynamic balance alterations among patients with headache. [METHODS] Electronic databases (PubMed, CINAHL, and Web of Science) were searched by two researchers independently up to September 2021. Two reviewers selected eligible studies, extracted the data, and a...
gait; headache disorders; migraine; postural balance; tension-type headache
1.283
146
Neurology; Neurology
Medicine; Neuroscience
2,022