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35,877,244
Surgical Management of Craniovertebral Junction Schwannomas: A Systematic Review.
Current oncology (Toronto, Ont.)
Curr Oncol
29
7
10.3390/curroncol29070384
eng
2,022
7
9
2,022
7
9
[BACKGROUND] Craniovertebral junction (CVJ) schwannomas are rare, with surgery and stereotactic radiosurgery (SRS) being effective yet challenging options. We systematically reviewed the literature on CVJ schwannomas. [METHODS] PubMed, Scopus, Web-of-Science, and Cochrane were searched following the PRISMA statement to...
cranial nerve tumor; craniovertebral junction; neuro-oncology; peripheral nerve tumor; schwannoma; skull base; spine
0.729
76
Oncology
Medicine
2,022
35,876,861
Gap distribution mapping to visualize regions associated with type 1 endoleak in a fenestrated thoracic stent graft.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Eur J Cardiothorac Surg
62
2
10.1093/ejcts/ezac361
eng
2,022
7
11
null
null
null
[OBJECTIVES] Our goal was to analyse the relationships between aortic surface irregularity and a type 1 endoleak (T1EL) after a thoracic endovascular repair using the Najuta fenestrated stent graft. [METHODS] The patients who were treated using the Najuta stent graft for an intact aortic arch aneurysm at the Saitama Ca...
Thoracic aortic aneurysm; endoleak; endovascular aortic repair; fenestrated graft system
1.183
158
Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,022
35,876,668
Intracranial Pressure Monitoring in Patients With Severe Traumatic Brain Injury: Extension of the Recommendations and the Effect on Outcome by Propensity Score Matching.
Neurosurgery
Neurosurgery
91
3
10.1227/neu.0000000000002044
eng
2,022
9
1
2,022
7
14
[BACKGROUND] Intracranial pressure (ICP) monitoring is recommended for patients with traumatic brain injury (TBI) with a Glasgow Coma Scale (GCS) <9 on admission and revealing space-occupying lesions or swelling on computed tomography. However, previous studies that have evaluated its effect on outcome have shown confl...
null
1.221
229
Neurology; Surgery
Medicine
2,022
35,876,481
Coping with suicide loss: a qualitative study in primary health care.
Primary health care research & development
Prim Health Care Res Dev
23
null
10.1017/S1463423622000263
eng
2,022
7
25
2,022
7
25
[AIM] To analyze how people cope with suicide loss and the implications for primary health care. [BACKGROUND] Previous studies have shown that primary health care will often be an initial source of support for those bereaved by suicide. [METHODS] We included adult persons who were ready to talk about a suicide complete...
bereavement; consultation; death and dying; mental health; primary care; suicide
null
null
null
null
null
35,876,246
An mHealth-Supported antenatal lifestyle intervention may be associated with improved maternal sleep in pregnancy: Secondary analysis from the PEARS trial.
BJOG : an international journal of obstetrics and gynaecology
BJOG
129
13
10.1111/1471-0528.17267
eng
2,022
12
null
2,022
8
8
[OBJECTIVE] To investigate the effect of an antenatal diet and exercise intervention during pregnancy on sleep duration. As a secondary objective, associations between sleep duration and gestational weight gain (GWG), maternal metabolic parameters and pregnancy outcomes were assessed. [DESIGN] Secondary analysis. [SETT...
breastfeeding; metabolism; nutrition; obesity; obstetrics; pregnancy; sleep; triglycerides; weight
2.203
195
Obstetrics and Gynecology
Medicine
2,022
35,875,623
Preoperative opiate use leads to increased postoperative opiate use and readmissions after anterior cervical discectomy and fusion.
Journal of spine surgery (Hong Kong)
J Spine Surg
8
2
10.21037/jss-21-126
eng
2,022
6
null
null
null
null
[BACKGROUND] Determine effects of pre-operative opiate use on anterior cervical discectomy and fusion (ACDF) surgery outcomes. [METHODS] The study design was a single center retrospective cohort study. Patient records were reviewed from 2013 and 2018 for elective 1 to 2 level ACDF surgeries. Patients were classified as...
opiates; pain; spine surgery
1.061
30
Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,875,427
17β-Estradiol Concentration and Direct β2-Adrenoceptor Inhibition Determine Estrogen-Mediated Reversal of Adrenergic Immunosuppression.
Annals of neurosciences
Ann Neurosci
29
1
10.1177/09727531211070541
eng
2,022
1
null
2,022
3
3
[BACKGROUND] Sympathetic innervation of lymphoid organs, and the presence of 17β-estradiol (estrogen or E2) and adrenergic receptors (ARs) on lymphocytes, suggests that sympathetic stimulation and hormonal activation may influence immune functions. [PURPOSE] Modeling and simulating these pathways may help to understand...
Immunomodulation; Norepinephrine; P-ERK; T-cell
null
null
null
null
null
35,875,097
Arecoline Is Associated With Inhibition of Cuproptosis and Proliferation of Cancer-Associated Fibroblasts in Oral Squamous Cell Carcinoma: A Potential Mechanism for Tumor Metastasis.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.925743
eng
2,022
null
null
2,022
7
7
[BACKGROUND] Metastatic disease remains the primary cause of death in patients with oral squamous cell carcinoma (OSCC), especially those who use betel nut. The different steps of the metastatic cascade rely on reciprocal interactions between cancer cells and the tumor microenvironment (TME). Cancer-associated fibrobla...
arecoline; cancer-associated fibroblasts; cuproptosis; metastasis; oral squamous cell carcinoma
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,874,582
Efficacy, Immunogenicity and Safety of Vaccination in Pediatric Patients With Autoimmune Inflammatory Rheumatic Diseases (pedAIIRD): A Systematic Literature Review for the 2021 Update of the EULAR/PRES Recommendations.
Frontiers in pediatrics
Front Pediatr
10
null
10.3389/fped.2022.910026
eng
2,022
null
null
2,022
7
6
[BACKGROUND] In 2011, the first European League Against Rheumatism (EULAR) vaccination recommendations for pediatric patients with autoimmune inflammatory rheumatic diseases (pedAIIRD) were published. The past decade numerous new studies were performed to assess the safety, efficacy and immunogenicity of vaccinations i...
immunosuppressants; pediatric immunology; pediatric rheumatic disease; safety; vaccination; vaccination responses
0.798
83
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,873,861
Adherence of ticagrelOr in real world patients with aCute coronary syndrome: The AD-HOC study.
International journal of cardiology. Heart & vasculature
Int J Cardiol Heart Vasc
42
null
10.1016/j.ijcha.2022.101092
eng
2,022
10
null
2,022
7
18
[BACKGROUND] Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor antagonist is the cornerstone of therapy in patients with acute coronary syndrome (ACS). Adherence to medical therapy is an important issue, as premature DAPT discontinuation increases the risk of new ischemic events. The aim of the present...
Acute coronary syndrome; Adherence; Discontinuation; Dual antiplatelet therapy; Ticagrelor
null
null
null
null
null
35,873,711
Vaspin Alleviates Sepsis-Induced Cardiac Injury and Cardiac Inflammation by Inhibiting Kallikrein 7 in Mice.
Mediators of inflammation
Mediators Inflamm
2022
null
10.1155/2022/1149582
eng
2,022
null
null
2,022
7
15
[BACKGROUND] Vaspin is an important adipokine that is involved in cardiovascular diseases. This study is aimed at investigating whether vaspin participates in sepsis-induced cardiac injury and explored the possible mechanism. [METHODS] First, cecal ligation and puncture (CLP) and lipopolysaccharide (LPS) were used to e...
null
0.962
145
Cell Biology; Immunology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
2,022
35,873,295
Epidemiology of Antimicrobial Resistance Among Blood and Respiratory Specimens in the United States Using Genotypic Analysis From a Cloud-Based Population Surveillance Network.
Open forum infectious diseases
Open Forum Infect Dis
9
7
10.1093/ofid/ofac296
eng
2,022
7
null
2,022
6
17
[BACKGROUND] Antimicrobial resistance (AMR) surveillance is critical in informing strategies for infection control in slowing the spread of resistant organisms and for antimicrobial stewardship in the care of patients. However, significant challenges exist in timely and comprehensive AMR surveillance. [METHODS] Using B...
antimicrobial resistance; healthcare epidemiology; surveillance
1.498
74
Infectious Diseases; Oncology
Medicine
2,022
35,873,258
Disruptive Behaviors and Intellectual Disability: Creating a New Script.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.851490
eng
2,022
null
null
2,022
7
8
[BACKGROUND] Terms currently used to describe the so-called challenging and disruptive behaviors (CBDs) of children with intellectual disabilities (ID) have different connotations depending on guiding contextual frameworks, such as academic and cultural settings in which they are used. A non-judgmental approach, which ...
Down syndrome; disruptive behavior; intellectual disability; physical activity; sleep
1.222
134
Psychiatry and Mental Health
Medicine
2,022
35,873,008
Comparisons of the Relationships Between Multiple Lipid Indices and Diabetic Kidney Disease in Patients With Type 2 Diabetes: A Cross-Sectional Study.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
13
null
10.3389/fendo.2022.888599
eng
2,022
null
null
2,022
7
6
[BACKGROUND] Dyslipidemia is a well-recognized risk factor for diabetic kidney disease (DKD) in patients with type 2 diabetes (T2D). Growing evidences have shown that compared with the traditional lipid parameters, some lipid ratios may provide additional information of lipid metabolism. Thus, the present study aimed t...
diabetic kidney disease; lipid indices; small dense low-density lipoprotein cholesterol; type 2 diabetes
1.278
138
Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,872,950
The Impact of Atorvastatin on RANKL Expression in Rats during the Retention Stage after Orthodontic Tooth Movement.
Computational and mathematical methods in medicine
Comput Math Methods Med
2022
null
10.1155/2022/7416572
eng
2,022
null
null
2,022
7
14
[OBJECTIVE] To probe into the impact of atorvastatin on RANKL expression in rats during the retention stage after orthodontic tooth movement and its associated molecular mechanisms. [METHODS] After establishing an orthodontic tooth movement model, the left teeth of the retention-stage rats were the maintained side, and...
null
null
null
null
null
null
35,872,526
Cannabis use for sleep aid among high school students: Concurrent and prospective associations with substance use and sleep problems.
Addictive behaviors
Addict Behav
134
null
10.1016/j.addbeh.2022.107427
eng
2,022
11
null
2,022
7
16
[INTRODUCTION] Adolescents are at risk for both sleep problems and cannabis use. Despite emerging evidence for college students' self-medication with cannabis to help sleep, generalizability to earlier developmental stages remains unknown. This study remedied this literature gap by characterizing high school students' ...
Adolescent; Cannabis; Mood; Self-medication; Sleep; Substance use
1.328
158
Clinical Psychology; Medicine; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics; Psychology
2,022
35,872,294
Overexpression of mcr-1 disrupts cell envelope synthesis and causes the dysregulation of carbon metabolism, redox balance and nucleic acids.
International journal of antimicrobial agents
Int J Antimicrob Agents
60
3
10.1016/j.ijantimicag.2022.106643
eng
2,022
9
null
2,022
7
22
[INTRODUCTION] Rapid dissemination of plasmid-borne polymyxin resistance mcr-1 genes threatens the efficacy of polymyxins. Acquisition of mcr-1 imposes a fitness cost on bacteria; identifying the molecular mechanisms underpinning this fitness cost will help in the development of adjunctive antimicrobial therapies that ...
Fitness cost; Gene expression; Polymyxin; Transcriptomics; mcr-1
1.297
161
Infectious Diseases; Medicine; Microbiology; Pharmacology
Medicine
2,022
35,872,130
Development of Consensus-Based Recommendations to Prevent/Minimize Medication Errors in the Perioperative Care of Patients with Epilepsy: A Mixed-Method.
World neurosurgery
World Neurosurg
166
null
10.1016/j.wneu.2022.07.069
eng
2,022
10
null
2,022
7
21
[BACKGROUND] This study explored medication errors in the perioperative care of patients with epilepsy and developed consensus-based recommendations to prevent/minimize these errors. [METHODS] A mixed method was used in this study. Medication error situations were explored in semi-structured in-depth interviews with nu...
Anesthesia; Antiseizure medications; Epilepsy; Medication errors; Perioperative care; Surgery
0.591
123
Neurology; Surgery
Medicine
2,022
35,872,091
Examining the intrinsic foot muscles' capacity to modulate plantar flexor gearing and ankle joint contributions to propulsion in vertical jumping.
Journal of sport and health science
J Sport Health Sci
12
5
10.1016/j.jshs.2022.07.002
eng
2,023
9
null
2,022
7
21
[BACKGROUND] During human locomotion, a sufficiently stiff foot allows the ankle plantar flexors to generate large propulsive powers. Increasing foot stiffness (e.g., via a carbon plate) increases the ankle's external moment arm in relation to the internal moment arm (i.e., increasing gear ratio), reduces plantar flexo...
Ankle biomechanics; Ankle gearing; Foot biomechanics
2.744
76
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation
Health Professions; Medicine
2,023
35,872,064
Cadmium exposure is associated with testosterone levels in men: A cross-sectional study from the China National Human Biomonitoring.
Chemosphere
Chemosphere
307
Pt 2
10.1016/j.chemosphere.2022.135786
eng
2,022
11
null
2,022
7
21
[BACKGROUND] Sex hormone disorders can cause adverse health consequences. While experimental data suggests that cadmium (Cd) disrupts the endocrine system, little is known about the link between Cd exposure and sex hormones in men. [METHODS] We measured blood cadmium (B-Cd), urine cadmium (U-Cd), serum testosterone and...
Cadmium; China National Human Biomonitoring; Endocrine disruptor; Testosterone; Testosterone to estradiol ratio; Toxic metals
1.727
329
Chemistry; Environmental Chemistry; Environmental Engineering; Health, Toxicology and Mutagenesis; Medicine; Pollution; Public Health, Environmental and Occupational Health
Chemistry; Environmental Science; Medicine
2,022
35,871,653
Incidence of pulmonary tuberculosis under the regular COVID-19 epidemic prevention and control in China.
BMC infectious diseases
BMC Infect Dis
22
1
10.1186/s12879-022-07620-y
eng
2,022
7
24
2,022
7
24
[BACKGROUND] The COVID-19 pandemic has driven public health intervention strategies, including keeping social distance, wearing masks in crowded places, and having good health habits, to prevent the transmission of the novel coronavirus (SARS-CoV-2). However, it is unknown whether the use of these intervention strategi...
COVID-19; Incidence; Intervention; Model; Tuberculosis
1.055
137
Infectious Diseases
Medicine
2,022
35,871,641
Understanding beliefs related to physical activity in people living with axial Spondyloarthritis: a theory-informed qualitative study.
BMC rheumatology
BMC Rheumatol
6
1
10.1186/s41927-022-00270-2
eng
2,022
7
25
2,022
7
25
[BACKGROUND] People living with axial Spondyloarthrtis (axSpA) have an increased risk of cardiovascular diseases, which can be reduced by regular physical activity (PA) and its subset of cardiorespiratory training (CRT). To fulfil their crucial role in PA promotion, physiotherapists and other health professionals need ...
Attitudes; Axial Spondyloarthritis; Beliefs; Cardiorespiratory training; Exercise; Physical activity; Theory of planned behaviour
0.703
25
Rheumatology
Medicine
2,022
35,871,536
Association between sociodemographic, obstetric, and lifestyle factors among Hungarian pregnant women-A cross-sectional study.
The journal of obstetrics and gynaecology research
J Obstet Gynaecol Res
48
10
10.1111/jog.15364
eng
2,022
10
null
2,022
7
24
[AIM] To learn the association between sociodemographic and obstetric factors and lifestyle characteristics of pregnant women, and to identify factors that can influence pregnant women's health consciousness. [METHODS] A cross-sectional, questionnaire-based study was performed among women who gave birth in Szeged in 20...
health behavior; health literacy; healthy lifestyle; maternal behavior; pregnancy
0.487
68
Obstetrics and Gynecology; Medicine
Medicine
2,022
35,871,390
Using machine learning for mortality prediction and risk stratification in atezolizumab-treated cancer patients: Integrative analysis of eight clinical trials.
Cancer medicine
Cancer Med
12
3
10.1002/cam4.5060
eng
2,023
2
null
2,022
7
24
[BACKGROUND] Few models exist to predict mortality in cancer patients receiving immunotherapy. Our aim was to build a machine learning-based risk stratification model for predicting mortality in atezolizumab-treated cancer patients. [METHODS] Data from 2538 patients in eight atezolizumab-treated cancer clinical trials ...
cancer immunotherapy; machine learning; mortality prediction; risk stratification
1.174
95
Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
35,871,382
Improved active participation among patients with severe acquired brain injury in early rehabilitation: Implementation of a professional competence development intervention.
Work (Reading, Mass.)
Work
72
4
10.3233/WOR-205343
eng
2,022
null
null
null
null
null
[BACKGROUND] In 2019, an educational programme was implemented in a sub-acute in-hospital neurorehabilitation clinic for patients with severe acquired brain injury (sABI). The programme was initiated to enhance staff competencies related to identifying and improving active participation among patients with sABI. [OBJEC...
Health services research; brain injuries; implementation; professional competence; public health professional; rehabilitation education
null
null
null
null
null
35,870,932
Factors associated with care- and health-related quality of life of caregivers of children with juvenile idiopathic arthritis.
Pediatric rheumatology online journal
Pediatr Rheumatol Online J
20
1
10.1186/s12969-022-00713-7
eng
2,022
7
23
2,022
7
23
[OBJECTIVE] This study investigates the relationship of child, caregiver, and caring context measurements with the care-related quality of life (CRQoL) and health-related quality of life (HRQoL) of caregivers of children with juvenile idiopathic arthritis (JIA). [METHODS] We performed a cross-sectional analysis of base...
null
null
null
null
null
null
35,870,571
Glycated hemoglobin levels and risk of all-cause and cause-specific mortality in hemodialysis patients with diabetes.
Diabetes research and clinical practice
Diabetes Res Clin Pract
190
null
10.1016/j.diabres.2022.110016
eng
2,022
8
null
2,022
7
21
[AIM] Adequate glycemic control is fundamental for improving clinical outcomes in hemodialysis patients with diabetes. However, the target for glycated hemoglobin (HbA1c) level and whether cause-specific mortality differs based on HbA1c levels remain unclear. [METHODS] A total of 24,243 HD patients with diabetes were e...
All-cause death; Cardiovascular death; Cause-specific mortality; End-stage kidney disease; HbA(1c); Hemodialysis
1.634
146
Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,870,558
Impact of trained intensivist coverage on survival outcomes after in-hospital cardiopulmonary resuscitation: A nationwide cohort study in South Korea.
Resuscitation
Resuscitation
178
null
10.1016/j.resuscitation.2022.07.022
eng
2,022
9
null
2,022
7
21
[AIM] We aimed to investigate whether trained intensivist coverage affects survival outcomes following in-hospital cardiopulmonary resuscitation (ICPR) for in-hospital cardiac arrest (IHCA). [METHODS] All adult patients who received ICPR for IHCA between January 1, 2016 and December 31, 2019 in South Korea were include...
Cardiac arrest; Cardiopulmonary resuscitation; Critical Care; Intensive care units; Resuscitation
2.242
162
Cardiology and Cardiovascular Medicine; Emergency Medicine; Emergency Nursing
Medicine; Nursing
2,022
35,870,251
Aberrant visual-related networks in familial cortical myoclonic tremor with epilepsy.
Parkinsonism & related disorders
Parkinsonism Relat Disord
101
null
10.1016/j.parkreldis.2022.07.001
eng
2,022
8
null
2,022
7
19
[INTRODUCTION] In familial cortical myoclonic tremor with epilepsy, photic stimulation can trigger visual symptoms and induce a photoparoxysmal response, or photosensitivity, on electroencephalography. However, the mechanism is poorly understood. In this study, we aimed to explore the neuroimaging changes related to vi...
Familial cortical myoclonic tremor with epilepsy; Photosensitivity; Primary visual cortex
null
null
null
null
null
35,870,130
Risk factor analysis for cytomegalovirus reactivation under prophylaxis with letermovir after allogeneic hematopoietic stem cell transplantation.
Transplant infectious disease : an official journal of the Transplantation Society
Transpl Infect Dis
24
6
10.1111/tid.13904
eng
2,022
12
null
2,022
7
28
[BACKGROUND] Letermovir has been approved as a novel cytomegalovirus (CMV) prophylactic agent after allogeneic hematopoietic stem cell transplantation (HSCT). However, there are still insufficient data to properly evaluate the real-world role of letermovir, and the risk factors for CMV reactivation under letermovir pro...
allogeneic hematopoietic stem cell transplantation; cytomegalovirus; letermovir; prophylaxis; serostatus
0.632
79
Infectious Diseases; Transplantation
Medicine
2,022
35,870,041
Development and validation of a novel nomogram to predict diabetic kidney disease in patients with type 2 diabetic mellitus and proteinuric kidney disease.
International urology and nephrology
Int Urol Nephrol
55
1
10.1007/s11255-022-03299-x
eng
2,023
1
null
2,022
7
23
[PURPOSE] Differentiating between diabetic kidney disease (DKD) and non-diabetic kidney disease (NDKD) in patients with Type 2 diabetes mellitus (T2DM) is important due to implications on treatment and prognosis. Clinical methods to accurately distinguish DKD from NDKD are lacking. We aimed to develop and validate a no...
Diabetic kidney disease; Diabetic nephropathy; Glomerulonephritis; Kidney biopsy; Nomogram; Non-diabetic kidney disease; Prediction Tool
0.538
69
Nephrology; Urology
Medicine
2,023
35,870,004
The incidence of concha bullosa: a retrospective radiologic study.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Eur Arch Otorhinolaryngol
280
2
10.1007/s00405-022-07552-y
eng
2,023
2
null
2,022
7
23
[AIM] This study was conducted to discuss the incidence, directions, and types of concha bullosa using studies in the literature. [MATERIALS AND METHODS] The images of patients who presented to the ENT clinic with different ENT symptoms in the last 7 years and had paranasal sinus tomography were analyzed retrospectivel...
Bulbous type; Extensive type; Lamellar type; Middle concha bullosa; Superior concha bullosa
0.792
94
Otorhinolaryngology; Medicine
Medicine
2,023
35,869,896
Choose Wisely: Surgical Selection of Candidates for Outpatient Anterior Cervical Surgery Based on Early Complications Among Inpatients.
The Journal of bone and joint surgery. American volume
J Bone Joint Surg Am
104
20
10.2106/JBJS.21.01356
eng
2,022
10
19
2,022
7
22
[BACKGROUND] Anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) are attractive targets for transition to the outpatient setting. We assessed the prevalence of rapid responses and major complications in the inpatient setting following 1 or 2-level ACDFs and CDAs. We evaluated factors tha...
null
null
null
null
null
null
35,869,521
Gross tumor volume delineation in primary prostate cancer on [18]F-PSMA-1007 PET/MRI and [68]Ga-PSMA-11 PET/MRI.
Cancer imaging : the official publication of the International Cancer Imaging Society
Cancer Imaging
22
1
10.1186/s40644-022-00475-1
eng
2,022
7
22
2,022
7
22
[BACKGROUND] We aimed to assess the clinical value of [18]F-PSMA-1007 and [68]Ga-PSMA-11 PET/MRI in the gross tumor volume (GTV) delineation of radiotherapy for prostate cancer (PCa). [METHODS] Sixty-nine patients were retrospectively enrolled (57 in the [18]F subgroup and 12 in the [68]Ga subgroup). Three physicians d...
Gross tumor volume; PSMA PET/MRI; Prostate cancer; Radiotherapy
1.231
69
Medicine; Oncology; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,022
35,869,420
ccImpute: an accurate and scalable consensus clustering based algorithm to impute dropout events in the single-cell RNA-seq data.
BMC bioinformatics
BMC Bioinformatics
23
1
10.1186/s12859-022-04814-8
eng
2,022
7
22
2,022
7
22
[BACKGROUND] In recent years, the introduction of single-cell RNA sequencing (scRNA-seq) has enabled the analysis of a cell's transcriptome at an unprecedented granularity and processing speed. The experimental outcome of applying this technology is a [Formula: see text] matrix containing aggregated mRNA expression cou...
Downstream analysis; Dropout event; Imputation; Next generation sequencing; Single-cell; scRNA
1.1
251
Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
2,022
35,868,968
The Podoprint® plantar pressure platform: Evaluation of reliability and repeatability, and determination of the normality parameters.
Journal of tissue viability
J Tissue Viability
31
4
10.1016/j.jtv.2022.07.005
eng
2,022
11
null
2,022
7
16
[INTRODUCTION] The Podoprint® pressure platform system is widely used in routine podiatric clinical practice to measure plantar pressures. It allows non-invasive examination of the patient, and provides fast results with high levels of precision, reliability, and repeatability. Once these conditions have been demonstra...
Baropodometry; Foot; Plantar pressures; Reliability; Repeatability
0.572
45
Dermatology; Pathology and Forensic Medicine
Medicine
2,022
35,868,903
Safety and feasibility of laparoscopy-assisted surgery for gastrointestinal stromal tumors larger than 5 cm: Results of a retrospective, single-center series of 1,802 consecutive patients.
Surgery
Surgery
172
4
10.1016/j.surg.2022.04.049
eng
2,022
10
null
2,022
7
20
[BACKGROUND] The role of laparoscopy-assisted resection for treating gastrointestinal stromal tumors >5 cm is still disputed. We aimed to assess the advantages of laparoscopy-assisted resection for treating gastrointestinal stromal tumors >5 cm. [METHODS] In total, 1,802 patients with primary gastrointestinal stromal t...
null
null
null
null
null
null
35,868,619
Systemic therapy and perioperative management improve the prognosis of pancreatic ductal adenocarcinoma: A retrospective cohort study of 2000 consecutive cases.
International journal of surgery (London, England)
Int J Surg
104
null
10.1016/j.ijsu.2022.106786
eng
2,022
8
null
2,022
7
19
[OBJECTIVE] This study aimed to explore patterns of the treatment strategies of pancreatic ductal adenocarcinoma based on 2000 consecutive cases of a prospective database since 2012 to obtain new insights for future directions. [METHODS] Among 2000 patients enrolled in this study, 210 patients were excluded, and 710, 5...
Length of hospital stay; Pancreatic ductal adenocarcinoma; Post-operative complications; Prognosis; Systemic therapy
2.597
99
Medicine; Surgery
Medicine
2,022
35,867,812
Cellular debris on negative liquid-based cytology cervicovaginal smears.
Cytopathology : official journal of the British Society for Clinical Cytology
Cytopathology
33
6
10.1111/cyt.13170
eng
2,022
11
null
2,022
8
12
[OBJECTIVES] To determine the prevalence of cellular debris (CD) on benign cervicovaginal liquid-based cytology (LBC) smears and which factors predict the presence and larger amount of CD. [METHODS] Cervicovaginal smears evaluated as negative for intraepithelial lesion or malignancy (NILM) between 1 January and 31 Marc...
Papanicolaou smear; cellular debris; cervical cancer; liquid-based cytology; necrosis; necrotic debris
0.465
56
Pathology and Forensic Medicine; Histology; Medicine
Medicine
2,022
35,867,608
Clinical Indicators of Surgical Outcomes After Laminoplasty for Patients With Cervical Ossification of the Posterior Longitudinal Ligament: A Prospective Multicenter Study.
Spine
Spine (Phila Pa 1976)
47
15
10.1097/BRS.0000000000004359
eng
2,022
8
1
2,022
7
15
[STUDY DESIGN] A prospective multicenter study. [OBJECTIVE] This study aims to evaluate patient-reported outcomes using the Japanese Orthopedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ) and clarify clinical factors that affect the therapeutic effects for patients with cervical ossification of t...
null
1.197
300
Neurology; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,022
35,867,585
Outcomes Following Direct Versus Indirect Decompression Techniques for Lumbar Spondylolisthesis: A Propensity-Matched Analysis.
Spine
Spine (Phila Pa 1976)
47
20
10.1097/BRS.0000000000004396
eng
2,022
10
15
2,022
7
15
[STUDY DESIGN] Retrospective review. [OBJECTIVE] The aim was to compare outcomes at 3 and 12 months for patients with lumbar spondylolisthesis treated with direct decompression (DD) versus indirect decompression (ID) techniques. [SUMMARY OF BACKGROUND DATA] Debate persists regarding the optimal surgical strategy to tre...
null
1.197
300
Neurology; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,022
35,867,394
Hemodialysis Record Sharing: Solution for Work Burden Reduction and Disaster Preparedness.
JMIR formative research
JMIR Form Res
6
7
10.2196/32925
eng
2,022
7
22
2,022
7
22
[BACKGROUND] After the Great East Japan Earthquake in 2011, backup systems for clinical information were launched in Japan. The system in Miyagi Prefecture called the Miyagi Medical and Welfare Information Network (MMWIN) is used as a health information exchange network to share clinical information among various medic...
EHR; backup; clinical data; clinical information; clinical record; clinical report; data protection; data recovery; data security; data sharing; disaster; document sharing; electronic health record; health information exchange; hemodialysis; information exchange; information network; information sharing; kidney; medica...
0.592
31
Medicine; Health Informatics
Medicine
2,022
35,867,209
An Internally Validated Prognostic Risk-Score Model for Disease-Specific Survival in Clinical Stage I and II Merkel Cell Carcinoma.
Annals of surgical oncology
Ann Surg Oncol
29
11
10.1245/s10434-022-12201-z
eng
2,022
10
null
2,022
7
22
[BACKGROUND] Merkel cell carcinoma (MCC) is a rare cutaneous malignancy for which factors predictive of disease-specific survival (DSS) are poorly defined. [METHODS] Patients from six centers (2005-2020) with clinical stage I-II MCC who underwent sentinel lymph node (SLN) biopsy were included. Factors associated with D...
null
1.133
210
Surgery; Oncology
Medicine
2,022
35,866,412
Development of a claims-based flare algorithm for systemic lupus erythematosus.
Current medical research and opinion
Curr Med Res Opin
38
9
10.1080/03007995.2022.2101804
eng
2,022
9
null
2,022
7
26
[OBJECTIVE] To develop a claims-based algorithm identifying systemic lupus erythematosus (SLE) flares using a linked claims-electronic medical record (EMR) dataset. [METHODS] This study was a retrospective analysis of linked administrative claims and EMR data spanning 1 January 2003 to 31 March 2019. Included were adul...
Systemic lupus erythematosus; administrative claims; algorithm; disease flare; electronic medical records
0.643
125
Medicine
Medicine
2,022
35,865,997
Study on the Anti-demyelination Mechanism of Bu-Shen-Yi-Sui Capsule in the Central Nervous System Based on Network Pharmacology and Experimental Verification.
Mediators of inflammation
Mediators Inflamm
2022
null
10.1155/2022/9241261
eng
2,022
null
null
2,022
7
12
[METHODS] The potential active ingredients and corresponding potential targets of BSYS Capsule were obtained from the TCMSP, BATMAN-TCM, Swiss Target Prediction platform, and literature research. Disease targets of CNSD were explored through the GeneCards and the DisGeNET databases. The matching targets of BSYS in CNSD...
null
0.962
145
Cell Biology; Immunology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
2,022
35,865,540
High Number and Specific Comorbidities Could Impact the Immune Response in COVID-19 Patients.
Frontiers in immunology
Front Immunol
13
null
10.3389/fimmu.2022.899930
eng
2,022
null
null
2,022
7
5
[BACKGROUND] Cellular immunodeficiency and comorbidities are common in COVID-19 patients. [AIM] The purpose of this study was to investigate comorbidities impacting on the cellular immunity in COVID-19 patients. [METHODS] The research objects included 55 healthy controls and 718 COVID-19 patients who divided into the c...
comorbidities; coronavirus disease 2019 (COVID-19); immune response; impact; lymphocyte subsets
2.022
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
35,865,353
Responsive Thalamic Neurostimulation: A Systematic Review of a Promising Approach for Refractory Epilepsy.
Frontiers in human neuroscience
Front Hum Neurosci
16
null
10.3389/fnhum.2022.910345
eng
2,022
null
null
2,022
7
5
[INTRODUCTION] Responsive neurostimulation is an evolving therapeutic option for patients with treatment-refractory epilepsy. Open-loop, continuous stimulation of the anterior thalamic nuclei is the only approved modality, yet chronic stimulation rarely induces complete seizure remission and is associated with neuropsy...
deep brain stimulation; epilepsy; neuromodulation; responsive neurostimulation system; thalamic nuclei
0.787
168
Behavioral Neuroscience; Neurology; Neuropsychology and Physiological Psychology; Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience; Psychology
2,022
35,864,611
Microsurgical Excision of Vestibular Schwannoma with Facial Nerve Preservation: A Retrosigmoid Approach.
Neurology India
Neurol India
70
3
10.4103/0028-3886.349583
eng
2,022
null
null
null
null
null
[BACKGROUND] This video highlights the standard surgical steps of retrosigmoid craniotomy and excision of a moderately sized vestibular schwannoma with facial nerve preservation, with basic technical nuances to guide young neurosurgeons. [OBJECTIVE] A systematic step-by-step approach to microsurgical dissection and rem...
Extracapsular dissection; facial nerve preservation; neuromonitoring; retro sigmoid craniotomy; vestibular schwannoma
0.448
59
Neurology; Neurology
Medicine; Neuroscience
2,022
35,864,557
Reducing health disparities: Adherence to referrals for further diagnosis among asylum seeking children.
Public health nursing (Boston, Mass.)
Public Health Nurs
39
6
10.1111/phn.13120
eng
2,022
11
null
2,022
7
21
[OBJECTIVE] Asylum-seeking children are most vulnerable to health problems and non-utilization of health amenities. The aim of the study was to compare adherence with referrals for further diagnostic tests among asylum-seeking children and native Israeli children. [DESIGN] A retrospective cohort study. [SAMPLE] The stu...
asylum-seeking children; developmental, growth, physical disorders; health disparities; mother-child health clinics
0.697
63
Nursing; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,022
35,864,523
Change of renal function after short-term use of cardioprotective agents in patients with type 2 diabetes is not accurately assessed by the change of estimated glomerular filtration rate: an observational study.
Diabetology & metabolic syndrome
Diabetol Metab Syndr
14
1
10.1186/s13098-022-00874-1
eng
2,022
7
21
2,022
7
21
[BACKGROUND] After initiating cardioprotective agents, a fall of estimated glomerular filtration rate (eGFR) has been reported in several studies. Our goal was to evaluate the accuracy of change of Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) eGFR in patients with type 2 diabetes (T2D) after short-term p...
Change of renal function; Glomerular filtration rate; Inulin clearance; Type 2 diabetes
null
null
null
null
null
35,864,410
The Risk Factors and Clinical Features of Acanthamoeba Keratitis: First Time Detection of Acanthamoeba T5 Genotype from Keratitis Patients in Turkey.
Acta parasitologica
Acta Parasitol
67
3
10.1007/s11686-022-00596-4
eng
2,022
9
null
2,022
7
21
[PURPOSE] The primary aim of this study is to investigate Acanthamoeba in clinical samples of keratitis cases (n = 60), in contact lens (CL) and lens care solutions of asymptomatic CL users (n = 41), and to identify the genotypes in positive samples. The secondary aim is to assess the risk factors and clinical features...
Acanthamoeba; Contact lens; Cornea; Genotype; Keratitis; T5
0.478
43
Parasitology
Immunology and Microbiology
2,022
35,864,163
Transepithelial photorefractive keratectomy: a prospective randomized comparative study between the two-step and the single-step techniques.
Eye (London, England)
Eye (Lond)
37
8
10.1038/s41433-022-02174-4
eng
2,023
6
null
2,022
7
21
[OBJECTIVES] To assess and compare the six-month outcome of the two-step transepithelial phototherapeutic keratectomy- photorefractive keratectomy (PTK-PRK) and the single-step transepithelial PRK for myopia and myopic astigmatism. [METHODS] A prospective randomized study. The study enrolled 100 eyes of 50 patients wit...
null
null
null
null
null
null
35,864,158
LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis.
British journal of cancer
Br J Cancer
127
7
10.1038/s41416-022-01902-7
eng
2,022
10
null
2,022
7
21
[BACKGROUND] Distant metastasis and recurrence remain the main obstacle to nasopharyngeal carcinoma (NPC) treatment. However, the molecular mechanisms underlying NPC growth and metastasis are poorly understood. [METHODS] LHX2 expression was examined in NPC cell lines and NPC tissues using quantitative reverse transcrip...
null
2.867
281
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,863,967
A multicentric evaluation of pediatric lung transplantation in Italy.
The Journal of thoracic and cardiovascular surgery
J Thorac Cardiovasc Surg
165
4
10.1016/j.jtcvs.2022.06.010
eng
2,023
4
null
2,022
6
20
[BACKGROUND] Pediatric lung transplantation is performed in highly experienced centers due to the peculiar population characteristics. The literature is limited and not representative of individual countries' differences. The purpose of this study was to analyze the Italian experience. [METHODS] A multicentric retrospe...
bronchial complications; lung; pediatric; transplantation
1.744
225
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,023
35,863,832
Longitudinal examination of young married women's fertility and family planning intentions and how they relate to subsequent family planning use in Bihar and Uttar Pradesh India.
BMJ open
BMJ Open
12
7
10.1136/bmjopen-2022-064487
eng
2,022
7
21
2,022
7
21
[OBJECTIVES] This study examines which fertility and family planning (FP) intentions are related to subsequent FP use in a sample of young, married women in India. [DESIGN] We use 3-year longitudinal data from married women ages 15-19 in 2015-2016 (wave 1) who are not using contraception to examine factors associated w...
PUBLIC HEALTH; REPRODUCTIVE MEDICINE; STATISTICS & RESEARCH METHODS
1.059
176
Medicine
Medicine
2,022
35,863,548
Prognostic Value of Exercise Stress Echocardiography in Pediatric Cardiac Transplant Recipients.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
J Am Soc Echocardiogr
35
11
10.1016/j.echo.2022.07.006
eng
2,022
11
null
2,022
7
19
[BACKGROUND] Cardiac allograft vasculopathy (CAV) is a leading cause of long-term morbidity and mortality in pediatric heart transplant (HTx) recipients. Exercise stress echocardiography (ESE) has been shown to be useful in the detection of angiographically confirmed coronary artery disease in children. However, the pr...
Cardiac allograft vasculopathy; Cardiovascular death; Exercise stress echocardiography; Heart transplant; Pediatric
1.959
156
Cardiology and Cardiovascular Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,863,287
Bilateral ovarian mucinous carcinoma (stage III) with omental involvement and incidental hydronephrosis: A rare case report.
International journal of surgery case reports
Int J Surg Case Rep
97
null
10.1016/j.ijscr.2022.107415
eng
2,022
8
null
2,022
7
16
[INTRODUCTION] Though ovarian malignancies are common, mucinous ovarian carcinomas of high grade are rare. They usually occur in a young female under 40 years of age. Here, we present a case of mucinous ovarian carcinoma (stage III), with omental involvement and incidental hydronephrosis in a 67-year-old female patient...
Bilateral; Case report; Mucinous ovarian carcinoma; Omental involvement
0.193
31
Surgery
Medicine
2,022
35,863,262
Effect of metformin on outcome after acute ischemic stroke in patients with type 2 diabetes mellitus.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
31
9
10.1016/j.jstrokecerebrovasdis.2022.106648
eng
2,022
9
null
2,022
7
18
[INTRODUCTION] Diabetes mellitus is a well-known risk factor for ischemic stroke and is associated with unfavorable outcome after stroke. Metformin is recommended as first-line treatment in these patients. Pre-stroke metformin use might have neuroprotective properties resulting in reduced stroke severity. However, resu...
Acute ischemic stroke; Favorable outcome; Metformin; Type 2 diabetes mellitus
0.713
85
Rehabilitation; Surgery; Cardiology and Cardiovascular Medicine; Neurology
Medicine
2,022
35,863,061
Efficacy and Safety of 3 Versus 6 Months of Dual-Antiplatelet Therapy in Patients Implanted With a Coroflex ISAR Stents: A Prospective, Multicenter, Randomized Clinical Trial.
The Journal of invasive cardiology
J Invasive Cardiol
34
9
10.25270/jic/21.00330
eng
2,022
9
null
2,022
7
22
[BACKGROUND] The optimal duration of dual-antiplatelet therapy (DAPT) after implantation of a drug-eluting stent (DES), especially recently developed polymer-free DESs, is unknown. This study examined the efficacy and safety of 3- versus 6-month DAPT in patients implanted with Coroflex ISAR polymer-free DESs. [METHODS]...
coronary artery disease; drug-eluting stents; dual-antiplatelet therapy; duration of therapy; randomized controlled trial
0.383
66
Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,862,641
Procedure-Related Risk Factors for Surgical Site Infection in Dermatologic Surgery.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Dermatol Surg
48
10
10.1097/DSS.0000000000003546
eng
2,022
10
1
2,022
7
15
[BACKGROUND] Identifying risk factors is essential for preventing surgical site infections (SSIs) in dermatologic surgery. [OBJECTIVE] To analyze whether specific procedure-related factors are associated with SSI. [METHODS] This systematic review of the literature included MEDLINE, EMBASE, CENTRAL, and trial registers....
null
0.56
146
Dermatology; Medicine; Surgery
Medicine
2,022
35,862,158
Developmental activities of professional male British rugby-league players versus controls.
Science & medicine in football
Sci Med Footb
6
3
10.1080/24733938.2021.1948093
eng
2,022
8
null
2,021
6
30
[PURPOSE] Many rugby league clubs rely on developing youth athletes into experts in adulthood. One factor that contributes to the attainment of expertise is the activities that athletes engage in across their development. Therefore, the developmental activities of professional male British rugby league players were com...
Expert performance; development pathways; skill acquisition; talent development
null
null
null
null
null
35,862,062
Association of Outpatient Oral Macrolide Use With Sensorineural Hearing Loss in Children, Adolescents, and Young Adults.
JAMA otolaryngology-- head & neck surgery
JAMA Otolaryngol Head Neck Surg
148
9
10.1001/jamaoto.2022.1293
eng
2,022
9
1
null
null
null
[IMPORTANCE] Prior publications have reported the sporadic development of sensorineural hearing loss (SNHL) after intravenous or high-dose macrolide therapy for adults with comorbid conditions, but investigations of the auditory effect of oral outpatient dosing for children, adolescents, and young adults have been limi...
null
null
null
null
null
null
35,861,968
Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model for TNNT2 Δ160E-Induced Cardiomyopathy.
Circulation. Genomic and precision medicine
Circ Genom Precis Med
15
5
10.1161/CIRCGEN.121.003522
eng
2,022
10
null
2,022
7
12
[BACKGROUND] The Δ160E mutation in TNNT2, which encodes troponin T, is a rare pathogenic variant identified in patients with hypertrophic cardiomyopathy and is associated with poor prognosis. Thus, a convenient human model recapitulating the pathological phenotype caused by TNNT2 Δ160E is required for therapeutic devel...
cardiomyopathy, hypertrophic; heart failure; mutation; phenotype; prognosis; troponin
null
null
null
null
null
35,861,780
Thirty-Day and 90-Day Episode of Care Spending Following Heart Failure Hospitalization Among Medicare Beneficiaries.
Circulation. Cardiovascular quality and outcomes
Circ Cardiovasc Qual Outcomes
15
7
10.1161/CIRCOUTCOMES.121.008069
eng
2,022
7
null
2,022
7
5
[BACKGROUND] Despite growing interest in value-based models, utilization patterns and costs for heart failure (HF) admissions are not well understood. We sought to characterize Medicare spending for patients with HF for 30- and 90-day episodes of care (which include an index hospitalization and 30 or 90 days following ...
episode of care; heart failure; hospitalization; medicare
null
null
null
null
null
35,861,678
Developing a Long COVID Phenotype for Postacute COVID-19 in a National Primary Care Sentinel Cohort: Observational Retrospective Database Analysis.
JMIR public health and surveillance
JMIR Public Health Surveill
8
8
10.2196/36989
eng
2,022
8
11
2,022
8
11
[BACKGROUND] Following COVID-19, up to 40% of people have ongoing health problems, referred to as postacute COVID-19 or long COVID (LC). LC varies from a single persisting symptom to a complex multisystem disease. Research has flagged that this condition is underrecorded in primary care records, and seeks to better def...
BioPortal; COVID-19; SARS-CoV-2; Systematized Nomenclature of Medicine; biomedical ontologies; computerized; data accuracy; data extracts; digital tool; disease management; electronic health record; epidemiology; ethnicity; general practitioners; hospitalization; long COVID; medical record systems; phenotype; postacute...
1.547
64
Health Informatics; Public Health, Environmental and Occupational Health
Medicine
2,022
35,861,637
Global Examination of Mental State: An open tool for the brief evaluation of cognition.
Brain and behavior
Brain Behav
12
8
10.1002/brb3.2710
eng
2,022
8
null
2,022
7
21
[BACKGROUND] The aim of this paper is to present a freely accessible new instrument for the evaluation of cognition: the Global Examination of Mental State (GEMS). [METHODS] It is made up of 11 items tapping into a range of skills, such as Orientation in time and space, Memory, Working memory, Visuo-spatial, Visuo-cons...
cognitive screening; neuropsychology; open tool; psychometric properties
0.834
69
Behavioral Neuroscience
Neuroscience
2,022
35,861,499
Evaluation of polypharmacy among chronic kidney disease patients in Egypt: A cross-sectional study.
International journal of clinical pharmacology and therapeutics
Int J Clin Pharmacol Ther
60
9
10.5414/CP204249
eng
2,022
9
null
null
null
null
[OBJECTIVE] To analyze the prevalence and the hazard of polypharmacy in chronic kidney disease (CKD) patients with different CKD stages in an Egyptian nephrology clinic. [MATERIALS AND METHODS] A cross-sectional observational study was performed between November and December 2021 in a private nephrology clinic in Egypt...
null
null
null
null
null
null
35,861,125
The influence of multidisciplinary team meetings on treatment decisions in advanced bladder cancer.
BJU international
BJU Int
131
2
10.1111/bju.15856
eng
2,023
2
null
2,022
8
5
[OBJECTIVES] To investigate the role of specialised genitourinary multidisciplinary team meetings (MDTMs) in decision-making and identify factors that influence the probability of receiving a treatment plan with curative intent for patients with muscle invasive bladder cancer (MIBC). [PATIENTS AND METHODS] Data relatin...
#BladderCancer; #blcsm; #uroonc; curative intent treatment; multidisciplinary team meeting; muscle-invasive bladder cancer; radical cystectomy hospital; treatment advice
1.337
174
Urology
Medicine
2,023
35,860,846
Novel mutations of PMFBP1 in a man with acephalic spermatozoa defects.
Molecular genetics & genomic medicine
Mol Genet Genomic Med
10
9
10.1002/mgg3.2020
eng
2,022
9
null
2,022
7
20
[BACKGROUND] Acephalic spermatozoa (AS) is a serious but rare reproductive genetic disorder that causes infertility in men. To date, only a few genes associated with AS defects have been identified, including the polyamine modulated factor 1 binding protein 1 (PMFBP1) gene. Consistent with this, PMFBP1 localizes to the...
PMFBP1 gene; acephalic spermatozoa; headless sperm; truncated protein
null
null
null
null
null
35,860,830
Comprehensive analysis of MET mutations in NSCLC patients in a real-world setting.
Therapeutic advances in medical oncology
Ther Adv Med Oncol
14
null
10.1177/17588359221112474
eng
2,022
null
null
2,022
7
16
[BACKGROUND] Aberrant mesenchymal-epithelial transition/hepatocyte growth factor (MET/HGF) regulation presented in a wide variety of human cancers. MET exon 14 skipping, copy number gain (CNG), and kinase domain mutations/arrangements were associated with increased MET activity, and considered to be oncogenic drivers o...
MET mutation; MET-TKI; actionable mutations; genetics; non-small cell lung cancer
1.514
74
Oncology
Medicine
2,022
35,860,735
Do Relapses Follow ANCA Rises? A Systematic Review and Meta-Analysis on the Value of Serial ANCA Level Evaluation.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.844112
eng
2,022
null
null
2,022
7
4
[OBJECTIVES] ANCA-vasculitis (AAV) patients frequently suffer from relapses and risk subsequent organ damage. There is much debate on the value of serial ANCA level evaluation to monitor disease activity. We aimed to evaluate the association between ANCA rises and disease relapses at (I) moment of the rise, (II) within...
ANCA-associated vasculitis (AAV); anti-neutrophil cytoplasmic antibodies (ANCA); biomarker (BM); flare; relapse
0.926
102
Medicine
Medicine
2,022
35,860,706
Immediate Effects of Electrical Stimulation on Oropharyngeal Structure and Laryngeal Vestibular Closure: A Pilot Study in Healthy Subjects.
Progress in rehabilitation medicine
Prog Rehabil Med
7
null
10.2490/prm.20220033
eng
2,022
null
null
2,022
7
9
[OBJECTIVES] This study examined the immediate effects of neuromuscular electrical stimulation (NMES) on the dynamics of oropharyngeal structure and laryngeal vestibular closure (LVC) in healthy subjects. [METHODS] Ten healthy male volunteers participated in this controlled, before-and-after, videofluoroscopic swallowi...
hyoid laryngeal proximity; laryngeal vestibular closure; neuromuscular electrical stimulation; swallowing
null
null
null
null
null
35,860,558
Multi-Omics Integration-Based Prioritisation of Competing Endogenous RNA Regulation Networks in Small Cell Lung Cancer: Molecular Characteristics and Drug Candidates.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.904865
eng
2,022
null
null
2,022
7
4
[BACKGROUND] The competing endogenous RNA (ceRNA) network-mediated regulatory mechanisms in small cell lung cancer (SCLC) remain largely unknown. This study aimed to integrate multi-omics profiles, including the transcriptome, regulome, genome and pharmacogenome profiles, to elucidate prioritised ceRNA characteristics,...
circular RNA (circRNA); competing endogenous RNA (ceRNA); long noncoding RNA (lncRNA); microRNA (miRNA); multi-omics integration; small cell lung cancer (SCLC)
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,859,690
Fibroblast Growth Factor 21 Levels and Bone Mineral Density in Metabolically Healthy and Metabolically Unhealthy Obese Children.
Journal of clinical research in pediatric endocrinology
J Clin Res Pediatr Endocrinol
14
4
10.4274/jcrpe.galenos.2022.2022-1-15
eng
2,022
12
1
2,022
7
21
[OBJECTIVE] The harmful or beneficial effect of obesity on bone mineral density (BMD) remains controversial in children and adolescents. Fibroblast growth factor 21 (FGF21) is a metabolic factor that plays a specific role in the regulation of carbohydrate and lipid metabolism. However, the role of FGF21 in bone metabol...
FGF21; Obesity; bone mineral density; children
null
null
null
null
null
35,859,671
Navigating Personal and Professional Development Through Social Media in Ophthalmology.
Clinical ophthalmology (Auckland, N.Z.)
Clin Ophthalmol
16
null
10.2147/OPTH.S368674
eng
2,022
null
null
2,022
7
13
[BACKGROUND] Although social media use among physicians skyrocketed during the COVID-19 pandemic, its role for networking, mentorship, and support among ophthalmologists remains unknown. The objective of this study was to elucidate how ophthalmologists use social media for navigating challenges related to personal and ...
mentorship; professional development; social media; women in ophthalmology
0.76
84
Ophthalmology
Medicine
2,022
35,858,759
Relationship between the number of lymph nodes dissected and prognosis in muscle-invasive bladder cancer in the era of neoadjuvant chemotherapy.
International journal of urology : official journal of the Japanese Urological Association
Int J Urol
29
11
10.1111/iju.14974
eng
2,022
11
null
2,022
7
20
[OBJECTIVES] Many studies have shown a good prognostic association with a large number of lymph node dissections. However, most of these studies did not include patients who have received neoadjuvant chemotherapy. The purpose of this study was to verify the relationship between survival outcomes and the number of lymph...
bladder cancer; cystectomy; lymph node dissection; neoadjuvant chemotherapy; urothelial cancer
0.694
83
Urology
Medicine
2,022
35,858,671
[Translated article] A 3D method to estimate the effect of derotational osteotomies over femoral maltorsion.
Revista espanola de cirugia ortopedica y traumatologia
Rev Esp Cir Ortop Traumatol
66
6
10.1016/j.recot.2022.07.016
eng
2,022
null
null
2,022
7
17
[INTRODUCTION AND OBJECTIVES] Accurate measurement of femoral torsion is essential to diagnosing, correct surgical decision-making, and the preoperative planning of derotational osteotomies in a subgroup of anterior knee pain patients and patellofemoral instability. Several measurement techniques have been described wi...
Anterior knee pain; Dolor anterior de rodilla; Femoral maltorsion; Femoral osteotomy; Inestabilidad patelofemoral; Patellofemoral instability
0.274
20
Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,858,633
Trend of fluctuations of antithrombin in plasma of patients with COVID-19: a meta-analysis and systematic review.
Expert review of hematology
Expert Rev Hematol
15
8
10.1080/17474086.2022.2104708
eng
2,022
8
null
2,022
7
29
[BACKGROUND] Antithrombin is considered as one of the accused markers for the development of thrombosis in patients with COVID-19. Because plasma levels of antithrombin vary in patients with COVID-19, a meta-analysis was performed to determine the trend of antithrombin levels in patients with COVID-19. [RESEARCH DESIGN...
Antithrombin; COVID-19; SARS-CoV-2; thrombosis
null
null
null
null
null
35,858,128
Holistic Admissions Review Integration in Nursing Programs.
The Journal of nursing education
J Nurs Educ
61
7
10.3928/01484834-20220610-01
eng
2,022
7
null
2,022
7
1
[BACKGROUND] To address health inequities, the American Association of Colleges of Nursing, Institute of Medicine, and Association of American Medical Colleges recommend holistic admissions review (HAR) to increase health professional diversity. [METHOD] This cross-sectional study collected admissions criteria from 1,5...
null
0.628
80
Nursing; Education
Nursing; Social Sciences
2,022
35,857,216
Metabolomics for the design of new metabolic engineering strategies for improving aerobic succinic acid production in Escherichia coli.
Metabolomics : Official journal of the Metabolomic Society
Metabolomics
18
8
10.1007/s11306-022-01912-9
eng
2,022
7
20
2,022
7
20
[INTRODUCTION] Glycerol is a byproduct from the biodiesel industry that can be biotransformed by Escherichia coli to high added-value products such as succinate under aerobic conditions. The main genetic engineering strategies to achieve this aim involve the mutation of succinate dehydrogenase (sdhA) gene and also thos...
Escherichia coli; Metabolomics; Succinic acid; TCA cycle
0.762
103
Biochemistry; Clinical Biochemistry; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,856,467
Craniofacial structures, occlusal features, and TMD symptoms in juvenile idiopathic arthritis patients: a retrospective study.
European journal of orthodontics
Eur J Orthod
45
1
10.1093/ejo/cjac037
eng
2,023
2
10
null
null
null
[BACKGROUND] Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease in which temporomandibular joint (TMJ) arthritis commonly occurs. It may be asymptomatic and could cause problems in the growing joints. Our aim was to evaluate the craniofacial structures, occlusal features and temporomandibular dysfunc...
null
0.94
105
Orthodontics
Dentistry
2,023
35,856,384
Awareness, knowledge, attitudes, and practices before the second wave of the COVID-19 pandemic in Saudi Arabia.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
26
13
10.26355/eurrev_202207_29217
eng
2,022
7
null
null
null
null
[OBJECTIVE] The COVID-19 outbreak was first reported in Wuhan City, China in early December 2019. It was declared a pandemic by WHO in March 2020. This study aimed at assessing the knowledge, awareness, and attitudes of the general population in Saudi Arabia towards COVID-19, as well as its adherence to preventive meas...
null
null
null
null
null
null
35,856,379
N-acetylcysteine as a therapeutic approach to post-COVID-19 pulmonary fibrosis adjunctive treatment.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
26
13
10.26355/eurrev_202207_29212
eng
2,022
7
null
null
null
null
[OBJECTIVE] Growing interest is directed to the outcomes of COVID-19 in survivors, both in the convalescent period and in the long-term, which are responsible for morbidity and quality of life deterioration. This article aims to describe the mechanisms supporting the possible use of NAC as an adjuvant treatment for pos...
null
null
null
null
null
null
35,856,326
Vibratory Anesthesia's Effect on Pain Perception in Upper Extremity Corticosteroid Injections.
Hand (New York, N.Y.)
Hand (N Y)
19
2
10.1177/15589447221109910
eng
2,024
3
null
2,022
7
20
[BACKGROUND] Prior studies have investigated the use of vibratory anesthesia for injectional pain reduction in dental, ophthalmologic, and plastic surgery literature. Scarce research has been aimed at determining the effect of vibratory anesthesia on hand and upper extremity injections. It is common practice for surgeo...
corticosteroid injections; pain perception; upper extremity injections; vibratory anesthesia
0.745
50
Surgery; Orthopedics and Sports Medicine
Medicine
2,024
35,855,534
The prevalence of obstructive sleep apnea in sarcoidosis and its impact on sleepiness, fatigue, and sleep-associated quality of life: a cross-sectional study with matched controls (the OSASA study).
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
J Clin Sleep Med
18
10
10.5664/jcsm.10140
eng
2,022
10
1
null
null
null
[STUDY OBJECTIVES] Patients with sarcoidosis experience fatigue and excessive daytime sleepiness (EDS). However, the underlying pathomechanism is unclear. Studies suggested undiagnosed obstructive sleep apnea (OSA) to be an important contributor, but reliable data on prevalence and impact of OSA in sarcoidosis are scar...
AHI; fatigue; obstructive sleep apnea; sarcoidosis
0.988
129
Neurology; Neurology; Pulmonary and Respiratory Medicine
Medicine; Neuroscience
2,022
35,855,498
The effectiveness of psychoeducational interventions on family function among families after stroke: A meta-analysis.
International journal of nursing practice
Int J Nurs Pract
28
6
10.1111/ijn.13081
eng
2,022
12
null
2,022
7
19
[AIMS] This meta-analysis aimed to synthesize the available evidence on the effectiveness of psychoeducational interventions on family function among families after stroke. [BACKGROUND] Family function may be improved by psychoeducational intervention, but findings about the effect of psychoeducation on family function...
family caregivers; family function; psychoeducational intervention; stroke survivors
0.614
66
Nursing
Nursing
2,022
35,855,168
Rapid sequential development and rupture of mycotic aneurysms within a period of days in a patient with graft-versus-host disease and angiotropic Scedosporium apiospermum infection.
Surgical neurology international
Surg Neurol Int
13
null
10.25259/SNI_970_2021
eng
2,022
null
null
2,022
6
10
[BACKGROUND] Fungal origin mycotic aneurysms are rare and carry a high mortality rate. Scedosporium apiospermum is an ubiquitous fungus which has been described to cause devastating infections in immunocompromised hosts. [CASE DESCRIPTION] We report a case of a 23-year-old patient with Burkitt's lymphoma and graft-vers...
Mycotic aneurysm; Scedosporium apiospermum; Surgery
0.256
48
Surgery; Neurology
Medicine
2,022
35,855,129
Small ruptured intracranial aneurysms are overrepresented at the anterior and posterior communicating artery: Results of a multiple regression analysis.
Surgical neurology international
Surg Neurol Int
13
null
10.25259/SNI_1119_2021
eng
2,022
null
null
2,022
7
8
[BACKGROUND] Anterior communicating artery (AcomA) represents the most common location for ruptured intracranial aneurysms (rIAs). Approximately 50% of all rIAs are smaller than 7 mm, but factors that lead to rupture are multifactorial. The study investigates whether AcomA location represents an independent risk factor...
Rupture risk; Small aneurysms; Unruptured intracranial aneurysm
0.256
48
Surgery; Neurology
Medicine
2,022
35,854,978
Variants of SLC2A10 may be Linked to Poor Response to Metformin.
Journal of the Endocrine Society
J Endocr Soc
6
8
10.1210/jendso/bvac092
eng
2,022
8
1
2,022
6
29
[PURPOSE] A study among Filipinos revealed that only 15% of patients with diabetes achieved glycemic control, and poor response to metformin could be one of the possible reasons. Recent studies demonstrate how genetic variations influence response to metformin. Hence, the present study aimed to determine genetic varian...
SLC2A10; metformin response; pharmacogenetics
0.98
50
Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,854,937
Complexity of understanding the role of dietary and erythrocyte docosahexaenoic acid (DHA) on the cognitive performance of school-age children.
Current developments in nutrition
Curr Dev Nutr
6
7
10.1093/cdn/nzac099
eng
2,022
7
null
2,022
6
16
[BACKGROUND] Early childhood is a period of rapid brain development, with increases in synapses rich in the omega-3 (ω-3) fatty acid, DHA (22:6ω-3) continuing well beyond infancy. Despite the importance of DHA to neural phospholipids, the requirement of dietary DHA for neurodevelopment remains unclear. [OBJECTIVES] The...
DHA intake; DHA status; brain development; children; cognitive performance; dietary assessment
0.888
41
Food Science; Medicine; Nutrition and Dietetics
Agricultural and Biological Sciences; Medicine; Nursing
2,022
35,854,874
Cross-Linked Hyaluronic Acid for Cleft Lip and Palate Aesthetic Correction: A Preliminary Report.
Aesthetic surgery journal. Open forum
Aesthet Surg J Open Forum
4
null
10.1093/asjof/ojac052
eng
2,022
null
null
2,022
6
8
[BACKGROUND] Surgical treatment of cleft lip and palate is divided into primary and secondary procedures to restore physiological function and appearance of the face, mouth, and nose. Hyaluronic acid (HA) bio-implants have been successfully used for volume loss correction in several medical disciplines. However, there ...
null
null
null
null
null
null
35,854,857
Peripheral intravenous catheters in the care of oncology and haematology patients.
The Australian journal of cancer nursing
Aust J Cancer Nurs
23
1
10.33235/ajcn.23.1.16-22
eng
2,022
5
null
null
null
null
[AIM] To determine peripheral intravenous catheter (PIVC) characteristics, complications and risk factors among patients in cancer units. [METHODS] A secondary analysis of a global, cross-sectional study (127 hospitals in 24 countries). Participants (≥18 years) admitted to cancer units were assessed once for PIVC chara...
haematology; oncology; peripheral venous catheter
null
null
null
null
null
35,854,644
Effect of sodium-glucose cotransporter 2 inhibitor medication on new prescriptions of antihypertensives, antigout/antihyperuricemics and antidyslipidemics in Japan: Analysis using the JMDC Claims Database.
Journal of diabetes investigation
J Diabetes Investig
13
11
10.1111/jdi.13887
eng
2,022
11
null
2,022
8
4
[AIMS/INTRODUCTION] This study aimed to investigate the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on new prescriptions of drugs, including antihypertensives, antigout/antihyperuricemics and antidyslipidemics, for the treatment of lifestyle-related diseases in Japanese patients with diabetes mellitus...
Claims database; Concomitant medication
0.992
75
Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,022
35,854,414
Indications, Clinical Impact, and Complications of Critical Care Transesophageal Echocardiography: A Scoping Review.
Journal of intensive care medicine
J Intensive Care Med
38
3
10.1177/08850666221115348
eng
2,023
3
null
2,022
7
19
[BACKGROUND] Critical care transesophageal echocardiography (ccTEE) is an increasingly popular tool used by intensivists to characterize and manage hemodynamics at the bedside. Its usage appears to be driven by expanded diagnostic scope as well as the limitations of transthoracic echocardiography (TTE) - lack of acoust...
cardiac arrest; critical care; diagnostic imaging; echocardiography; resuscitation; shock; ultrasound
1.043
75
Critical Care and Intensive Care Medicine
Medicine
2,023
35,854,201
A novel MRI index for paraspinal muscle fatty infiltration: reliability and relation to pain and disability in lumbar spinal stenosis: results from a multicentre study.
European radiology experimental
Eur Radiol Exp
6
1
10.1186/s41747-022-00284-y
eng
2,022
7
20
2,022
7
20
[BACKGROUND] Fatty infiltration of the paraspinal muscles may play a role in pain and disability in lumbar spinal stenosis. We assessed the reliability and association with clinical symptoms of a method for assessing fatty infiltration, a simplified muscle fat index (MFI). [METHODS] Preoperative axial T2-weighted magne...
Magnetic resonance imaging; Paraspinal muscles; Patient-reported outcome measures; Psoas muscles; Spinal stenosis
0.789
34
Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,853,763
Aspartate aminotransferase to alanine aminotransferase ratio and the risk of diabetic nephropathy progression in patients with type 2 diabetes mellitus: A biopsy-based study.
Journal of diabetes and its complications
J Diabetes Complications
36
8
10.1016/j.jdiacomp.2022.108235
eng
2,022
8
null
2,022
6
24
[PURPOSE] To study the relationship between baseline serum aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (AAR) in both clinicopathological features and renal outcome among type 2 diabetes mellitus (T2DM) patients with biopsy-confirmed diabetic nephropathy (DN). [METHODS] As a retrospective co...
AAR; Diabetic nephropathy; Prognosis
0.921
104
Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,853,561
Lifestyle factors associated with muscle quality in community-dwelling older people with type 2 diabetes in Japan and Taiwan: a cross-sectional study.
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society
Psychogeriatrics
22
5
10.1111/psyg.12878
eng
2,022
9
null
2,022
7
19
[BACKGROUND] Type 2 diabetes mellitus (T2DM), common in older people, is an important reason for muscle loss in Japanese and Taiwanese populations. However, little is known about the association between lifestyle behaviours and muscle quality. We aimed to compare the lifestyle behaviours of Japanese and Taiwanese older...
Asia; diabetes; lifestyle; muscle quality
0.556
46
Gerontology; Geriatrics and Gerontology; Psychiatry and Mental Health
Medicine; Nursing
2,022
35,852,845
Profiles of behavioral, social and psychological well-being in old age and their association with mobility-limitation-free survival.
Aging
Aging (Albany NY)
14
15
10.18632/aging.204182
eng
2,022
7
18
2,022
7
18
[INTRODUCTION] Successful aging is a multidimensional construct covering behavioral, social, and psychological domains of well-being. We aimed to identify well-being profiles and their association with mobility-limitation-free survival. [METHODS] A total of 1488 healthy individuals aged 60+ from the Swedish National st...
mobility; older adults; successful aging; survival; well-being
1.2
132
Aging; Cell Biology
Biochemistry, Genetics and Molecular Biology
2,022
35,852,720
Application of chemical factors for acceleration of consolidation phase of the distraction osteogenesis: a scoping review.
Oral and maxillofacial surgery
Oral Maxillofac Surg
27
4
10.1007/s10006-022-01097-4
eng
2,023
12
null
2,022
7
19
[PURPOSE] This study aimed to analyze the effect of injecting chemical factors compared to conventional distraction osteogenesis (DO) treatment on the bone formation of the distracted area of the maxillofacial region in human and animal studies. [METHOD] Electronic search was done in PubMed, Scopus, Embase, and Cochran...
Bone formation; Chemical factor; Distraction osteogenesis; Growth factor; Maximal load tolerance; Tissue engineering
0.491
43
Oral Surgery; Otorhinolaryngology; Surgery
Dentistry; Medicine
2,023
35,852,527
Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial.
JAMA
JAMA
328
3
10.1001/jama.2022.11016
eng
2,022
7
19
null
null
null
[IMPORTANCE] Exercise limitation is a cardinal manifestation of heart failure with reduced ejection fraction (HFrEF) but is not consistently improved by any of the current guideline-directed medical therapies. [OBJECTIVE] To determine whether omecamtiv mecarbil, a novel direct myosin activator that improves cardiac per...
null
null
null
null
null
null