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36,845,293
Novel genetically engineered H3.3G34R model reveals cooperation with ATRX loss in upregulation of Hoxa cluster genes and promotion of neuronal lineage.
Neuro-oncology advances
Neurooncol Adv
5
1
10.1093/noajnl/vdad003
eng
2,023
null
null
2,023
1
6
[BACKGROUND] Pediatric high-grade gliomas (pHGGs) are aggressive pediatric CNS tumors and an important subset are characterized by mutations in H3F3A, the gene that encodes Histone H3.3 (H3.3). Substitution of Glycine at position 34 of H3.3 with either Arginine or Valine (H3.3G34R/V), was recently described and charact...
ATRX; GEMM; H3.3G34R; HOXA; RCAS; mouse models; pediatric high-grade glioma
1.315
33
Neurology; Oncology; Surgery
Medicine
2,023
36,845,228
Evaluation of the health information system for monitoring and evaluating the voluntary medical male circumcision program in Mozambique, 2013-2019.
The Pan African medical journal
Pan Afr Med J
42
null
10.11604/pamj.2022.42.236.28534
eng
2,022
null
null
2,022
7
27
[INTRODUCTION] the prevalence of human immunodeficiency virus (HIV) in Mozambique has increased from 11.5% in 2009 to 13.2% in 2015. The Mozambique Ministry of Health (MOH) developed a 5-year strategy (2013-2017) for male voluntary medical circumcision (VMMC) to increase in the provinces where there is the greatest num...
HIV; Health information systems; Mozambique; VMMC; evaluation
0.33
53
Medicine
Medicine
2,022
36,845,012
Identify Key Genes Correlated to Ischemia-Reperfusion Injury in Aging Livers.
Disease markers
Dis Markers
2023
null
10.1155/2023/4352313
eng
2,023
null
null
2,023
2
16
[BACKGROUND] With the intensification of population aging, the proportion of aging livers in the donor pool is increasing rapidly. Compared with young livers, aging livers are more susceptible to ischemia-reperfusion injury (IRI) during liver transplantation, which greatly affects the utilization rate of aging livers. ...
null
null
85
Biochemistry; Clinical Biochemistry; Genetics; Medicine; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,844,961
Acute Pain Management and Perceptions among Emergency Healthcare Workers: Feedback from Greece.
Romanian journal of anaesthesia and intensive care
Rom J Anaesth Intensive Care
29
1
10.2478/rjaic-2022-0004
eng
2,022
7
null
2,023
1
14
[BACKGROUND AND AIMS] Pain remains the most common reason patients seek assistance in emergency rooms. However, the level of pain management during emergencies, and subsequently during disasters and mass casualty incidents, remainsdisturbing. [METHODS] A cross-sectional study was conducted using a structured anonymous ...
acute pain; emergency department; oligoanalgesia; opiophobia; pain attitude; questionnaire
null
null
null
null
null
36,844,224
Evaluation of COVID-19 vaccines in primary prevention against infections and reduction in severity of illness following the outbreak of SARS-CoV-2 omicron variant in Shanghai.
Frontiers in medicine
Front Med (Lausanne)
10
null
10.3389/fmed.2023.1079165
eng
2,023
null
null
2,023
2
8
[OBJECTIVES] To evaluate COVID-19 vaccines in primary prevention against infections and lessen the severity of illness following the most recent outbreak of the SARS-CoV-2 Omicron variant in Shanghai. [DATA SOURCES] Data from 153,544 COVID-19 patients admitted to the Shanghai "Four-Leaf Clover" Fangcang makeshift shelt...
COVID-19; epidemiology; health policy; public health; respiratory tract infections; vaccines
0.909
102
Medicine
Medicine
2,023
36,844,162
Adapting low-dose buprenorphine induction to meet patient needs: A pilot study.
Drug and alcohol dependence reports
Drug Alcohol Depend Rep
5
null
10.1016/j.dadr.2022.100104
eng
2,022
12
null
2,022
10
7
[INTRODUCTION] Low-dose buprenorphine induction (LDBI) has been proposed to initiate buprenorphine in patients who are taking full opioid agonists in order to limit the risk of precipitated withdrawal. The objective of this study was to understand how real-world patient-specific adjustments in LDBI protocols impacted s...
Buprenorphine; Buprenorphine/naloxone; Induction; Opioid use disorder
null
null
null
null
null
36,843,786
Evaluation of Clinical, Biochemical, and Demographic Characteristics of Paediatric COVID-19 Patients Admitted to Dicle University Hospital.
Cureus
Cureus
15
1
10.7759/cureus.34171
eng
2,023
1
null
2,023
1
24
[INTRODUCTION AND AIM] In this study, we aim to determine how laboratory parameters were related to the clinical courses of patients admitted to the Dicle University Faculty of Medicine Department of Paediatrics and Paediatric Intensive Care Unit with COVID-19 diagnoses from March 2020 to November 2021. [MATERIALS AND ...
clinical course; covid-19; ferritin; fibrinojen; mortality
null
null
null
null
null
36,843,321
Assessing the Quality and Impact of eHealth Tools: Systematic Literature Review and Narrative Synthesis.
JMIR human factors
JMIR Hum Factors
10
null
10.2196/45143
eng
2,023
3
23
2,023
3
23
[BACKGROUND] Technological advancements have opened the path for many technology providers to easily develop and introduce eHealth tools to the public. The use of these tools is increasingly recognized as a critical quality driver in health care; however, choosing a quality tool from the myriad of tools available for a...
digital health; eHealth; mHealth; mobile health; technology adoption; technology assessment; technology implementation
0.777
36
Health Informatics; Human Factors and Ergonomics
Medicine; Social Sciences
2,023
36,843,033
High Visceral-To-Subcutaneous Fat Ratio Is Associated with an Increased Risk of Gastroesophageal Reflux Disease in Nonobese Adults.
Digestive diseases (Basel, Switzerland)
Dig Dis
41
4
10.1159/000529814
eng
2,023
null
null
2,023
2
24
[INTRODUCTION] Abdominal obesity increases the risk of gastroesophageal reflux disease (GERD). This study aimed to determine the association between GERD and abdominal fat area quantified by computed tomography (CT). [METHODS] We analyzed the effect of abdominal fat area on gastroesophageal reflux symptoms and erosive ...
Esophagitis; Gastroesophageal reflux; Intra-abdominal fat; Obesity
0.744
83
Gastroenterology; Medicine
Medicine
2,023
36,842,891
Increasing the Repertoire for Depression Care: Methods and Challenges of a Randomized Controlled Trial of Peer Support for Vulnerable Older Adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Am J Geriatr Psychiatry
31
8
10.1016/j.jagp.2023.01.023
eng
2,023
8
null
2,023
2
2
[OBJECTIVE] Low-income White and older adults of color face barriers to depression care. Our purpose is to describe the methods and challenges encountered during the implementation of a randomized controlled trial to test the effectiveness of a peer support depression care intervention for low-income White and older ad...
Depression; Elderly; Ethnicity; Intervention; Peer support
1.913
150
Geriatrics and Gerontology; Psychiatry and Mental Health
Medicine
2,023
36,842,688
Anaesthetic management of tetraplegic pregnant patients during child delivery: A systematic review.
Revista espanola de anestesiologia y reanimacion
Rev Esp Anestesiol Reanim (Engl Ed)
70
4
10.1016/j.redare.2022.01.011
eng
2,023
4
null
2,023
2
25
[BACKGROUND] Pregnancy in spinal cord injured patients has specific issues that must be carefully addressed. However, guidelines for their management are scarce. [METHODS] A systematic review of the literature regarding the anaesthetic management during delivery of pregnant patients with cervical spinal cord injury was...
Autonomic dysreflexia; Complicaciones del parto; Labour complications; Obstetric analgesia; Tetraplegia; Tetraplejia
0.239
29
Anesthesiology and Pain Medicine; Critical Care and Intensive Care Medicine
Medicine
2,023
36,842,541
Effect of an Artificial Intelligence Decision Support Tool on Palliative Care Referral in Hospitalized Patients: A Randomized Clinical Trial.
Journal of pain and symptom management
J Pain Symptom Manage
66
1
10.1016/j.jpainsymman.2023.02.317
eng
2,023
7
null
2,023
2
24
[CONTEXT] Palliative care services are commonly provided to hospitalized patients, but accurately predicting who needs them remains a challenge. [OBJECTIVES] To assess the effectiveness on clinical outcomes of an artificial intelligence (AI)/machine learning (ML) decision support tool for predicting patient need for pa...
Artificial intelligence (AI); EHR; Inpatient palliative care; Machine learning (ML); Pragmatic clinical trials
1.186
171
Anesthesiology and Pain Medicine; Neurology; Nursing
Medicine; Nursing
2,023
36,841,661
Effectiveness of Lay Bystander Hands-Only Cardiopulmonary Resuscitation on a Mattress versus the Floor: A Randomized Cross-Over Trial.
Annals of emergency medicine
Ann Emerg Med
81
6
10.1016/j.annemergmed.2023.01.012
eng
2,023
6
null
2,023
2
24
[STUDY OBJECTIVE] Bystander cardiopulmonary resuscitation increases the likelihood of out-of-hospital cardiac arrest survival by more than two-fold. A common barrier to the prompt initiation of compressions is moving victims to the floor, but compression quality on a "floor" versus a "mattress" has not been tested amon...
null
0.937
178
Emergency Medicine
Medicine
2,023
36,841,644
A decade of fingolimod in multiple sclerosis: Insights from a large real-world cohort study.
Revue neurologique
Rev Neurol (Paris)
179
6
10.1016/j.neurol.2022.11.012
eng
2,023
6
null
2,023
2
24
[BACKGROUND AND OBJECTIVES] Ten years after its authorization, data about fingolimod use in real-world setting is still scarce. Here we describe the long-term evolution of fingolimod-treated relapsing-remitting MS (RRMS) patients and determine baseline characteristics associated with risk of relapses or disability. [ME...
Fingolimod; Follow-up studies; France; Multiple sclerosis; Relapsing remitting; Risk factors; Treatment outcome
0.786
61
Neurology; Neurology
Medicine; Neuroscience
2,023
36,841,327
Systematic Review and Meta-Analysis: Altered Autonomic Functioning in Youths With Emotional Dysregulation.
Journal of the American Academy of Child and Adolescent Psychiatry
J Am Acad Child Adolesc Psychiatry
63
2
10.1016/j.jaac.2023.01.017
eng
2,024
2
null
2,023
2
23
[OBJECTIVE] To systematically investigate if there is a significant association between markers of autonomic functioning and emotional dysregulation (ED) in children and adolescents. [METHOD] Based on a preregistered protocol (PROSPERO: CRD42021239635), PubMed, Web of Knowledge/Science, Ovid MEDLINE, Embase, and APA Ps...
EDA; HRV; RSA; autonomic nervous system; emotional dysregulation
3.005
282
Developmental and Educational Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
36,841,217
Substances from unregulated drug markets - A retrospective data analysis of customer-provided samples from a decade of drug checking service in Zurich (Switzerland).
The International journal on drug policy
Int J Drug Policy
114
null
10.1016/j.drugpo.2023.103972
eng
2,023
4
null
2,023
2
24
[BACKGROUND] Drug checking services (DCS) are harm reduction interventions for people who consume illicit substances. Unregulated drug markets lead to samples with unexpected and variable contents. A retrospective data analysis of Zurich's DCS was performed to determine the nature of these samples. [METHODS] This study...
Drug checking; Drug checking service; Drug testing; Fake; Harm reduction; Recreational drugs
null
null
null
null
null
36,841,175
Response of genes related to iron and porphyrin transport in Porphyromonas gingivalis to blue light.
Journal of photochemistry and photobiology. B, Biology
J Photochem Photobiol B
241
null
10.1016/j.jphotobiol.2023.112670
eng
2,023
4
null
2,023
2
14
[BACKGROUND] Antimicrobial blue light (aBL) kills a variety of bacteria, including Porphyromonas gingivalis. However, little is known about the transcriptomic response of P. gingivalis to aBL therapy. This study was designed to evaluate the selective cytotoxicity of aBL against P. gingivalis over human cells and to fur...
Blue light; Porphyromonas gingivalis; RNA-seq; ROS
null
null
null
null
null
36,840,805
Evaluation of Pain and Use of Analgesics during Medical Termination of Pregnancy in Real-Life Settings.
Pain and therapy
Pain Ther
12
2
10.1007/s40122-023-00477-2
eng
2,023
4
null
2,023
2
25
[INTRODUCTION] Women frequently report pain associated with medical termination of pregnancy (MToP), and its management can differ largely between centres. This study aimed at evaluating in real-life settings pain related to MToP and its management in France. [METHODS] This was a non-interventional prospective, longitu...
Medical termination of pregnancy; Mifepristone; Misoprostol; Pain management
0.847
41
Anesthesiology and Pain Medicine; Neurology
Medicine
2,023
36,840,358
Patients' experiences of Daily Talks: a patient-driven intervention in inpatient mental healthcare.
Journal of mental health (Abingdon, England)
J Ment Health
32
4
10.1080/09638237.2023.2182420
eng
2,023
8
null
2,023
2
24
[BACKGROUND] Recovery is known to be enhanced by meaningful interactions between patients and mental health staff. However, nurses may become distanced from patients, and patients may spend most of their time in inpatient mental health care alone. [AIMS] This study aimed to explore how patients experience the intervent...
Recovery; client staff relations; inpatient services; intervention study; mental health; mental health nurse; patient-driven innovation; psychiatry
1.061
88
Medicine; Psychiatry and Mental Health
Medicine
2,023
36,840,031
Optimization and In Vitro Characterization of Telmisartan Loaded Sodium Alginate Beads and Its In Vivo Efficacy Investigation in Hypertensive Induced Animal Model.
Pharmaceutics
Pharmaceutics
15
2
10.3390/pharmaceutics15020709
eng
2,023
2
20
2,023
2
20
[BACKGROUND] Antihypertensive drug telmisartan (TEL) belongs to BCS class II, which is characterized by low water solubility and, consequently, low oral bioavailability. Gastroretentive systems may overcome the problems associated with low solubility of TEL and incomplete absorption by localizing the drug release in th...
alginate polymer; anti-hypertension; bioavailability; central composite design; gastroretentive beads; in vitro buoyancy; telmisartan (TEL)
null
null
null
null
null
36,836,579
Evaluation of the Association between Low-Density Lipoprotein (LDL) and All-Cause Mortality in Geriatric Patients with Hip Fractures: A Prospective Cohort Study of 339 Patients.
Journal of personalized medicine
J Pers Med
13
2
10.3390/jpm13020345
eng
2,023
2
16
2,023
2
16
[BACKGROUND] Many factors affect the prognosis of hip fractures in the elderly. Some studies have suggested a direct or indirect association among serum lipid levels, osteoporosis, and hip fracture risk. LDL levels were found to have a statistically significant nonlinear U-shaped relationship with hip fracture risk. Ho...
LDL; cohort study; hip fractures; mortality
0.736
62
Medicine
Medicine
2,023
36,836,420
Jet Ventilation Reduces Coronary Sinus Movement in Patients Undergoing Atrial Fibrillation Ablation: An Observational Crossover Study.
Journal of personalized medicine
J Pers Med
13
2
10.3390/jpm13020186
eng
2,023
1
20
2,023
1
20
[BACKGROUND] One of the reasons that high-frequency jet ventilation (HFJV) is used is due to the near immobility of thoracic structures. However, no study has quantified the movements of cardiac structures during HFJV compared with normal mechanical ventilation. [METHODS] After ethical approval and written informed con...
atrial fibrillation ablation; high-frequency jet ventilation; intermittent positive pressure ventilation
0.736
62
Medicine
Medicine
2,023
36,835,996
First Nation-Wide Study of the Incidence and Characteristics of Retinal Detachment in Poland during 2013-2019.
Journal of clinical medicine
J Clin Med
12
4
10.3390/jcm12041461
eng
2,023
2
12
2,023
2
12
[AIMS] The present study aimed to analyze the incidence and characteristics of all types of retinal detachment (RD) in the overall population of Polish adults during 2013-2019. [METHODS] Data from all levels of healthcare services at public and private institutions recorded in the National Health Fund (NHF) database we...
rhegmatogenous RD; serous RD; traction RD
0.882
132
Medicine
Medicine
2,023
36,835,800
CRB-65 for Risk Stratification and Prediction of Prognosis in Pulmonary Embolism.
Journal of clinical medicine
J Clin Med
12
4
10.3390/jcm12041264
eng
2,023
2
5
2,023
2
5
[BACKGROUND] Pulmonary embolism (PE) is accompanied by high morbidity and mortality. The search for simple and easily assessable risk stratification scores with favourable effectiveness is still ongoing, and prognostic performance of the CRB-65 score in PE might promising. [METHODS] The German nationwide inpatient samp...
mortality; pneumonia; pulmonary embolism; risk stratification; venous thromboembolism
0.882
132
Medicine
Medicine
2,023
36,833,103
Effects of Iron Salts on Demineralization and Discoloration of Primary Incisor Enamel Subjected to Artificial Cariogenic Challenge versus Saline Immersion.
Healthcare (Basel, Switzerland)
Healthcare (Basel)
11
4
10.3390/healthcare11040569
eng
2,023
2
14
2,023
2
14
[AIM] This study aimed to assess the effects of iron salts on the demineralization and discoloration of primary incisor enamel subjected to artificial cariogenic challenge (ACC) versus saline immersion. [METHODOLOGY] In this in vitro experimental study, 90 primary incisors were evaluated in 10 groups (n = 9). Five grou...
anemia; deciduous tooth; iron compounds; iron-deficiency
0.863
33
Health Policy
Medicine
2,023
36,832,287
White Matter Lesions Identified by Magnetic Resonance in Women with Migraine: A Volumetric Analysis and Clinical Correlations.
Diagnostics (Basel, Switzerland)
Diagnostics (Basel)
13
4
10.3390/diagnostics13040799
eng
2,023
2
20
2,023
2
20
[BACKGROUND] Repeated migraine attacks and aura could independently cause structural changes in the central nervous system. Our research aims to study the correlation of migraine type, attack frequency, and other clinical variables with the presence, volume and localization of white matter lesions (WML), in a controlle...
magnetic resonance; migraine; volumetry; voxel-based morphometry; white matter lesions
0.667
81
Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology
2,023
36,830,956
Integration of Ultrastructural and Computational Approaches Reveals the Protective Effect of Astaxanthin against BPA-Induced Nephrotoxicity.
Biomedicines
Biomedicines
11
2
10.3390/biomedicines11020421
eng
2,023
2
1
2,023
2
1
[BACKGROUND] Bisphenol A (BPA) is an environmental contaminant that can induce deleterious organ effects. Human Cytochrome P450 CYP2C9 enzyme belongs to the essential xenobiotic-metabolizing enzymes, producing ROS as a byproduct. Astaxanthin (ATX) is a powerful antioxidant that protects organs and tissues from the dama...
ATX; BPA; CYP2C9; antioxidant; dynamics; kidneys
0.962
85
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,830,901
Relationship between Novel Elastography Techniques and Renal Fibrosis-Preliminary Experience in Patients with Chronic Glomerulonephritis.
Biomedicines
Biomedicines
11
2
10.3390/biomedicines11020365
eng
2,023
1
26
2,023
1
26
[INTRODUCTION] A renal biopsy represents the gold standard in the diagnosis, prognosis, and management of patients with glomerulonephritis. So far, non-invasive elastographic techniques have not confirmed their utility in replacing a biopsy; however, the new and improved software from Hologic Supersonic Mach 30 is a pr...
fibrosis; inflammation; renal biopsy; stiffness; viscosity
0.962
85
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,830,288
Overruling of Procalcitonin-Guided Antibiotics for Lower Respiratory Tract Infections in Primary Care: Ancillary Study of a Randomized Controlled Trial.
Antibiotics (Basel, Switzerland)
Antibiotics (Basel)
12
2
10.3390/antibiotics12020377
eng
2,023
2
12
2,023
2
12
[BACKGROUND] Lower respiratory tract infections (LRTIs) in primary care are a promising target for antibiotic stewardship. A clinical trial in Switzerland showed a large decrease in antibiotic prescriptions with procalcitonin guidance (cut-off 0.25 µg/L) compared with usual care. However, one-third of patients with lo...
antibiotic stewardship; overruling; primary health care; procalcitonin; respiratory infection
0.92
99
Pharmacology; Pharmacology, Toxicology and Pharmaceutics; Biochemistry; Infectious Diseases; Microbiology; Microbiology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,829,498
Rare Variants in LRP4 Are Associated with Mesiodens, Root Maldevelopment, and Oral Exostoses in Humans.
Biology
Biology (Basel)
12
2
10.3390/biology12020220
eng
2,023
1
30
2,023
1
30
[BACKGROUND] Low density lipoprotein receptor-related protein 4 (LRP4; MIM 604270) modulates WNT/β-catenin signaling, through its binding of WNT ligands, and to co-receptors LRP5/6, and WNT inhibitors DKK1, SOSTDC1, and SOST. LRP4 binds to SOSTDC1 and WNT proteins establishing a negative feedback loop between Wnt/β-cat...
buccal exostoses; root anomalies; root malformations; torus mandibularis; torus palatinus
0.815
91
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
2,023
36,829,247
Implementation costs of hospital-based computerised decision support systems: a systematic review.
Implementation science : IS
Implement Sci
18
1
10.1186/s13012-023-01261-8
eng
2,023
2
24
2,023
2
24
[BACKGROUND] The importance of accurately costing implementation strategies is increasingly recognised within the field of implementation science. However, there is a lack of methodological guidance for costing implementation, particularly within digital health settings. This study reports on a systematic review of cos...
CDSS; Computerised decision support systems; Digital health; Economic evaluation; Hospital; Implementation costs
2.964
157
Health Informatics; Health Policy; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,023
36,829,236
The presence of human respiratory syncytial virus in the cerebrospinal fluid of a child with Anti-N-methyl-D-aspartate receptor encephalitis of unknown trigger.
Virology journal
Virol J
20
1
10.1186/s12985-023-01997-1
eng
2,023
2
24
2,023
2
24
[BACKGROUND] Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an important type of brain inflammation caused by autoantibody. As one of the primary agents responsible for respiratory tract infection, the human respiratory syncytial virus (hRSV) has also been reported to be capable of causing extrapulmona...
Anti-N-methyl-D-aspartate receptor encephalitis; Children; Human respiratory syncytial virus; Transcriptome sequencing
1.016
104
Infectious Diseases; Virology
Immunology and Microbiology; Medicine
2,023
36,829,217
How gender is socially constructed in policy making processes: a case study of the Adolescent and Youth Health Policy in South Africa.
International journal for equity in health
Int J Equity Health
22
1
10.1186/s12939-022-01819-w
eng
2,023
2
24
2,023
2
24
[BACKGROUND] Gender equality remains an outstanding global priority, more than 25 years after the landmark Beijing Platform for Action. The disconnect between global health policy intentions and implementation is shaped by several conceptual, pragmatic and political factors, both globally and in South Africa. Actor nar...
Actors; Adolescent and youth health policy; Framing; Gender; Intersectionality; Narratives; Policy process; South Africa
1.692
93
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,023
36,829,202
Using protein-per-mRNA differences among human tissues in codon optimization.
Genome biology
Genome Biol
24
1
10.1186/s13059-023-02868-2
eng
2,023
2
24
2,023
2
24
[BACKGROUND] Codon usage and nucleotide composition of coding sequences have profound effects on protein expression. However, while it is recognized that different tissues have distinct tRNA profiles and codon usages in their transcriptomes, the effect of tissue-specific codon optimality on protein synthesis remains el...
Codon optimization; Gene design; Proteomics; Tissue; Transcriptomics; Translation
null
null
null
null
null
36,829,105
Transcriptomic profiling of the developing brain revealed cell-type and brain-region specificity in a mouse model of prenatal stress.
BMC genomics
BMC Genomics
24
1
10.1186/s12864-023-09186-8
eng
2,023
2
24
2,023
2
24
[BACKGROUND] Prenatal stress (PS) is considered as a risk factor for many mental disorders. PS-induced transcriptomic alterations may contribute to the functional dysregulation during brain development. Here, we used RNA-seq to explore changes of gene expression in the mouse fetal brain after prenatal exposure to chron...
Brain-region-specificity; Cell-type-specificity; Embryonic brain; Gene transcription; Maternal stress
1.047
208
Biotechnology; Genetics
Biochemistry, Genetics and Molecular Biology
2,023
36,829,064
Impact of the use of dental services on dental pain according to adolescents' skin colour: a 10-year cohort.
Clinical oral investigations
Clin Oral Investig
27
6
10.1007/s00784-023-04921-7
eng
2,023
6
null
2,023
2
25
[OBJECTIVE] Evaluate the association of the interaction between the use of dental services and the skin colour on the occurrence of dental pain over time. [MATERIAL AND METHODS] This study is a cohort with 10 years of follow-up, started in 2010 with a sample of 639 preschool children (1-5 years old). The use of dental ...
Adolescence; Dental care; Dental pain; Longitudinal study; Oral health; Race factors
0.942
108
Dentistry
Dentistry
2,023
36,828,965
Molecular sensors in the taste system of Drosophila.
Genes genomics
Genes Genomics
45
6
10.1007/s13258-023-01370-0
eng
2,023
6
null
2,023
2
24
[BACKGROUND] Most animals, including humans and insects, consume foods based on their senses. Feeding is mostly regulated by taste and smell. Recent insect studies shed insight into the cross-talk between taste and smell, sweetness and temperature, sweetness and texture, and other sensory modality pairings. Five canoni...
Drosophila; Gustatory receptor neuron; Multisensory interaction; Noncanonical taste; Taste
null
null
null
null
null
36,828,910
Carcinogenic risk in the biliary epithelium of children with congenital biliary dilatation via the DNA damage repair pathway.
Surgery today
Surg Today
53
10
10.1007/s00595-023-02664-2
eng
2,023
10
null
2,023
2
24
[PURPOSES] Congenital biliary dilatation (CBD) is a high-risk factor for biliary tract cancer (BTC). We previously reported the potential for carcinogenesis in the biliary epithelium of patients with CBD. In this study, we investigated potential carcinogenetic pathways, focusing on the DNA damage repair response, in ch...
Carcinogenesis; Congenital biliary dilatation; DNA damage repair pathway
0.719
77
Surgery; Medicine
Medicine
2,023
36,828,766
The use of complementary and traditional medicine for the treatment of patients with COVID-19: A systematic review.
Explore (New York, N.Y.)
Explore (NY)
19
5
10.1016/j.explore.2023.02.005
eng
2,023
null
null
2,023
2
21
[OBJECTIVE] The aim of this study was to evaluate the use and effectiveness of non-pharmacological therapies as part of the treatment of COVID-19 and its complications, either combined or not with the usual treatment. [METHODS] A systematic review was conducted between August and October 2021 using PubMed, Scopus, CINA...
COVID-19; Complementary therapies; Coronavirus; Nonpharmacological interventions; Traditional medicine
0.412
52
Chiropractics; Complementary and Alternative Medicine; Nursing; Analysis; Medicine
Health Professions; Mathematics; Medicine; Nursing
2,023
36,828,649
Availability of refractive error correction services in selected Zambian hospitals: a cross-sectional quantitative study.
BMJ open
BMJ Open
13
2
10.1136/bmjopen-2022-070297
eng
2,023
2
24
2,023
2
24
[OBJECTIVE] To assess the availability of refractive error correction services (RECS) in selected Zambian hospitals. [METHODS] Between October 2021 and March 2022, we conducted a cross-sectional study design among 20 eye health service providers selected from 20 public health facilities offering RECS in 20 districts fr...
EPIDEMIOLOGY; OPHTHALMOLOGY; PUBLIC HEALTH
0.971
176
Medicine
Medicine
2,023
36,827,921
Early mean absolute lymphocyte count in acute necrotizing pancreatitis is associated with infected pancreatic necrosis.
International immunopharmacology
Int Immunopharmacol
117
null
10.1016/j.intimp.2023.109883
eng
2,023
4
null
2,023
2
22
[OBJECTIVES] Peripheral absolute lymphocyte count (ALC) has the potential to predict infected pancreatic necrosis (IPN), but requires verification. This study aimed to assess whether early mean absolute lymphocyte count is associated with the development of IPN in ANP patients using pooled data from a multicenter, rand...
Absolute lymphocyte count; Acute necrotizing pancreatitis; Infected pancreatic necrosis; Quartile
1.167
155
Pharmacology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,827,677
Considering the Intercultural Development Inventory (IDI) to Assess Intercultural Competence at U.S. Pharmacy Schools.
Pharmacy (Basel, Switzerland)
Pharmacy (Basel)
11
1
10.3390/pharmacy11010039
eng
2,023
2
19
2,023
2
19
[BACKGROUND] U.S. pharmacy schools need to engage in improving intercultural competence among administrators, faculty, staff, and students. The Intercultural Development Inventory (IDI) can be a possible tool to determine the level of intercultural competence. U.S. pharmacy schools need to examine the validity of the I...
health professional education; intercultural competence; pharmacy education; the intercultural development inventory; validity
null
null
null
null
null
36,827,648
Using IPA tools to characterize molecular pathways underlying the involvement of IRF7 in antiviral response to HIV.
NeuroImmune pharmacology and therapeutics
NeuroImmune Pharm Ther
1
1
10.1515/nipt-2022-0009
eng
2,022
3
25
2,022
8
25
[OBJECTIVES] Interferon Regulatory Factors (IRFs) regulate transcription of type-I interferons (IFNs) and IFN-stimulated genes. We previously reported that IFN-regulatory factor 7 (IRF7) is significantly upregulated in the brain of HIV-1 transgenic (HIV-1Tg) rats compared to F344 control rats in a region dependent mann...
HIV; IRF7; bioinformatics; gene knockout; ingenuity pathway analysis; neuronal survival
null
null
null
null
null
36,827,609
Cortical Activation During Single-Legged Stance in Patients With Chronic Ankle Instability.
Journal of athletic training
J Athl Train
58
11-12
10.4085/1062-6050-0363.22
eng
2,023
11
1
null
null
null
[CONTEXT] Chronic ankle instability (CAI) has been considered a neurophysiological condition, with dysfunctional somatosensory and motor system excitability. However, few researchers have explored the changes in cortical activation during balance tasks of patients with CAI. [OBJECTIVE] To compare the cortical activity ...
central nervous system; coper; primary somatosensory cortex; superior temporal gyrus
1.141
139
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,023
36,827,380
Clinical and Surgical Characteristics of Patients with Atlantoaxial Dislocation in the Setting of Sandwich Fusion: A Case-Control Analysis of Over 500 Patients with Mid-Term to Long-Term Follow-up.
The Journal of bone and joint surgery. American volume
J Bone Joint Surg Am
105
10
10.2106/JBJS.22.01004
eng
2,023
5
17
2,023
2
24
[BACKGROUND] Patients with "sandwich" fusion (concomitant C1 occipitalization and C2-C3 nonsegmentation), a subtype of Klippel-Feil syndrome, are at particular risk for developing atlantoaxial dislocation (AAD). However, the clinical and surgical characteristics of AAD in patients with sandwich fusion have not been cle...
null
null
null
null
null
null
36,826,709
Characterization of cuproptosis identified immune microenvironment and prognosis in acute myeloid leukemia.
Clinical translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Clin Transl Oncol
25
8
10.1007/s12094-023-03118-4
eng
2,023
8
null
2,023
2
24
[BACKGROUND] Recent studies have reported that cuproptosis, a novel cell death pathway, strongly correlates with mitochondrial metabolism. In addition, the studies reported that cuproptosis plays a role in the development of several cancers and is regulated by protein lipoylation. During cuproptosis, copper binds to th...
Acute myeloid leukemia; Chemotherapy; Cuproptosis; Immune microenvironment; Immunotherapy; Prognostic signature
null
null
null
null
null
36,826,489
Outcomes of Self-Expanding Covered Stents for the Treatment of External ILIAC Artery Obstructive Disease.
Cardiovascular and interventional radiology
Cardiovasc Intervent Radiol
46
5
10.1007/s00270-023-03370-9
eng
2,023
5
null
2,023
2
24
[PURPOSE] To describe the early results and mid-term patency rates of external iliac artery (EIA) stenting using self-expanding covered stents. [METHODS] We conducted a multicenter retrospective study (2015-2021), including patients receiving primary endovascular treatment of external iliac artery occlusive disease wit...
Iliac artery; Multicenter study; Peripheral arterial disease; Self-expandable metallic stent; Stent
0.777
99
Cardiology and Cardiovascular Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,023
36,825,853
Development and testing of a decision aid to achieve shared decision-making for routine labor induction.
Birth (Berkeley, Calif.)
Birth
50
3
10.1111/birt.12716
eng
2,023
9
null
2,023
2
24
[BACKGROUND] This quality improvement project aimed to create a decision aid for labor induction in healthy pregnancies at or beyond 39 weeks that met the needs of pregnant people least likely to experience shared decision-making and to identify and test implementation strategies to support its use in prenatal care. [M...
decision aid; labor induction; shared decision-making
1.127
96
Obstetrics and Gynecology
Medicine
2,023
36,825,825
The impact of health literacy: associations with disease activity and medication prescription in patients with rheumatoid arthritis.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
62
10
10.1093/rheumatology/kead094
eng
2,023
10
3
null
null
null
[OBJECTIVE] The aim of this study was to explore the longitudinal associations between health literacy profiles and disease activity and medication prescription in patients with RA. [METHODS] Patients with RA who previously completed the Health Literacy Questionnaire (HLQ) and were assigned 1 of 10 distinct health lite...
RA; disease activity; health inequalities; health literacy; medication prescription
1.721
205
Pharmacology; Rheumatology
Medicine
2,023
36,825,724
Gambogic Acid Lysinate-induced Cervical Cancer SiHa Cells Apoptosis in vitro and in vivo.
Anti-cancer agents in medicinal chemistry
Anticancer Agents Med Chem
23
11
10.2174/1871520623666230223145706
eng
2,023
null
null
null
null
null
[BACKGROUND] Surgical resection and chemotherapy are the primary treatment options for cervical cancer; however, efficacy of chemotherapy drugs is limited by drug resistance. There is an urgent need to find new compounds. Gambogic acid lysinate (GAL), a new compound made from gambogic acid and lysine, has good anti-tum...
Gambogic acid lysinate; MTT assay; apoptosis; cell cycle arrest; cervical cancer; xenografts
null
null
null
null
null
36,825,516
Soluble IgE-binding factors in the serum of food-allergic patients: Possible pathophysiological role of soluble FcεRI as protective factor.
Clinical and translational allergy
Clin Transl Allergy
13
2
10.1002/clt2.12222
eng
2,023
2
null
null
null
null
[BACKGROUND] IgE-mediated food allergy is the result of an aberrant immune response involving the interaction of a food allergen with its specific IgE bound to FcɛRI, the high affinity IgE receptor, on mast cells. Allergen-specific IgE also binds to soluble binding factors, but, their expression and role in food allerg...
CD23; IgE receptor; food allergy; galectin-3; galectin-9
1.309
57
Immunology and Allergy; Pulmonary and Respiratory Medicine; Immunology
Immunology and Microbiology; Medicine
2,023
36,825,126
COVID-19 vaccine hesitancy trends in Ghana: a cross-sectional study exploring the roles of political allegiance, misinformation beliefs, and sociodemographic factors.
The Pan African medical journal
Pan Afr Med J
43
null
10.11604/pamj.2022.43.165.37314
eng
2,022
null
null
2,022
12
2
[INTRODUCTION] Africa has the slowest COVID-19 vaccination rate of any continent in the world, with only 29.8% of the population receiving at least one dose of the vaccine. This includes Ghana, where only 37.8% of the country have received at least one dose as of October, 2022. The key aims of this research were to det...
COVID-19; Ghana; West Africa; vaccine hesitancy; vaccines
0.33
53
Medicine
Medicine
2,022
36,824,881
Genetic Predictors of Blood Pressure Traits are Associated with Preeclampsia.
medRxiv : the preprint server for health sciences
medRxiv
null
null
10.1101/2023.02.09.23285734
eng
2,023
2
14
2,023
2
14
[BACKGROUND] Preeclampsia, a pregnancy complication characterized by hypertension after 20 gestational weeks, is a major cause of maternal and neonatal morbidity and mortality. The mechanisms leading to preeclampsia are unclear; however, there is evidence that preeclampsia is highly heritable. We evaluated the associat...
null
null
null
null
null
null
36,824,860
Early Treatment, Inflammation and Post-COVID Conditions.
medRxiv : the preprint server for health sciences
medRxiv
null
null
10.1101/2023.02.13.23285855
eng
2,023
2
16
2,023
2
16
[BACKGROUND] Post-COVID conditions (PCC) are common and have significant morbidity. Risk factors for PCC include advancing age, female sex, obesity, and diabetes mellitus. Little is known about early treatment, inflammation, and PCC. [METHODS] Among 883 individuals with confirmed SARS-CoV-2 infection participating in a...
COVID-19; COVID-19 serotherapy; chemokines; cytokines; interleukin-6; post COVID conditions (PCC); post-acute sequelae of COVID (PASC)
null
null
null
null
null
36,824,173
The clinical value of the Controlling Nutritional Status score for predicting prognosis in systolic heart failure cases in the vulnerable phase.
Frontiers in nutrition
Front Nutr
10
null
10.3389/fnut.2023.1084107
eng
2,023
null
null
2,023
2
7
[BACKGROUND] Malnutrition, a commonly encountered complication of heart failure, has an association with poor prognosis. The vulnerable phase of heart failure constitutes the most vulnerable stage of heart failure cases after discharge (usually within 3 months). At present, the prognostic value of Controlling Nutrition...
CONUT score; malnutrition; prognosis; systolic heart failure; vulnerable phase
0.828
94
Food Science; Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Agricultural and Biological Sciences; Medicine; Nursing
2,023
36,824,075
Outcome of structured health education intervention for obesity-risk reduction among junior high school students: Stratified cluster randomized controlled trial (RCT) in South India.
Journal of education and health promotion
J Educ Health Promot
11
null
10.4103/jehp.jehp_369_22
eng
2,022
null
null
2,022
12
28
[BACKGROUND] Obesity has been identified as a serious global health concern whose prevalence doubles almost every 10 years. Health education regarding physical activity and healthy diet imparted to adolescents could prove to be fruitful in reducing obesity-risk. Objectives of this study were to evaluate the effect of h...
Diet; obesity; overweight; physical activity; risk
0.411
30
Education; Medicine
Medicine; Social Sciences
2,022
36,823,618
Which interventions for alcohol use should be included in a universal healthcare benefit package? An umbrella review of targeted interventions to address harmful drinking and dependence.
BMC public health
BMC Public Health
23
1
10.1186/s12889-023-15152-6
eng
2,023
2
23
2,023
2
23
[BACKGROUND] This study aimed to identify targeted interventions for the prevention and treatment of harmful alcohol use. Umbrella review methodology was used to summarise the effectiveness across a broad range of interventions, in order to identify which interventions should be considered for inclusion within universa...
Abstinence; Alcohol use disorder; Harmful drinking; Interventions; Umbrella review; Universal health coverage
1.253
211
Public Health, Environmental and Occupational Health
Medicine
2,023
36,823,616
Patient dissatisfaction associated with physician-patient linguistic discordance in California clinics: an analytical cross-sectional study.
BMC health services research
BMC Health Serv Res
23
1
10.1186/s12913-023-09176-2
eng
2,023
2
23
2,023
2
23
[BACKGROUND] Patient satisfaction is considered as a product of two psychological processes, a cognitive one, including expectations and perceptions, and an emotional one resulting from the congruence between expectation and subjective perception of the user. The objective was to identify the factors associated with th...
Communication barriers; Emigration and immigration; Health services accessibility; Language; Patient satisfaction; Primary health care
1.029
157
Health Policy
Medicine
2,023
36,843,910
Alcohol use disorder treatment and outcomes among hospitalized adults with alcoholic hepatitis.
Drug and alcohol dependence reports
Drug Alcohol Depend Rep
1
null
10.1016/j.dadr.2021.100004
eng
2,021
12
null
2,021
11
17
[PURPOSE] : The burden of alcohol-associated liver disease (ALD) in the United States (US) has continued to worsen in the background of rising rates of alcohol use disorder. Patients with ALD present to care at a late stage, often with the sequela of liver decompensation, such as gastrointestinal bleeding and infection...
Alcohol-associated liver disease; Alcohol-use disorder; Alcoholic hepatitis
null
null
null
null
null
36,883,858
Diagnostic Imaging in the Evaluation of Asymptomatic Microhematuria: Systematic Review and Meta-analysis.
The Journal of urology
J Urol
209
6
10.1097/JU.0000000000003395
eng
2,023
6
null
2,023
3
8
[PURPOSE] Microhematuria is a highly prevalent condition with a low associated risk of urothelial and upper tract malignancy. The AUA Guidelines recently changed recommendations for imaging favoring renal ultrasound for low- and intermediate-risk patients with microhematuria. We summarize the diagnostic test characteri...
carcinoma, transitional cell; diagnostic imaging; hematuria; urography; urologic neoplasms
1.938
291
Urology
Medicine
2,023
36,882,855
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Experimental hematology & oncology
Exp Hematol Oncol
12
1
10.1186/s40164-023-00381-7
eng
2,023
3
7
2,023
3
7
[BACKGROUND] Cell cycle dysregulation characterized by cyclin D1 overexpression is common in mantle cell lymphoma (MCL), while mitotic disorder was less studied. Cell division cycle 20 homologue (CDC20), an essential mitotic regulator, was highly expressed in various tumors. Another common abnormality in MCL is p53 ina...
Apoptosis; CDC20; Mantle cell lymphoma; Proliferation; p53
null
null
null
null
null
36,882,837
Exercise activates Sirt1-mediated Drp1 acetylation and inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver disease.
Lipids in health and disease
Lipids Health Dis
22
1
10.1186/s12944-023-01798-z
eng
2,023
3
7
2,023
3
7
[PURPOSE] Aerobic exercise has shown beneficial effects in the prevention and treatment of non-alcoholic fatty liver disease (NAFLD). Nevertheless, the regulatory mechanism is not turely clear. Therefore, we aim to clarify the possible mechanism by investigating the effects of aerobic exercise on NAFLD and its mitochon...
Aerobic exercise; Drp1 acetylation; Mitochondrial dysfunction; NAFLD; Srit1
1.112
105
Biochemistry; Clinical Biochemistry; Endocrinology, Diabetes and Metabolism; Endocrinology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,882,739
Water intake, hydration status and 2-year changes in cognitive performance: a prospective cohort study.
BMC medicine
BMC Med
21
1
10.1186/s12916-023-02771-4
eng
2,023
3
8
2,023
3
8
[BACKGROUND] Water intake and hydration status have been suggested to impact cognition; however, longitudinal evidence is limited and often inconsistent. This study aimed to longitudinally assess the association between hydration status and water intake based on current recommendations, with changes in cognition in an ...
Cognition; Cognitive function; Cognitive performance; Fluids; Hydration; PREDIMED-plus; Serum osmolality; Serum osmolarity; Water
2.711
199
Medicine
Medicine
2,023
36,882,249
Characterising the burden of chronic kidney disease among people with type 2 diabetes in England: a cohort study using the Clinical Practice Research Datalink.
BMJ open
BMJ Open
13
3
10.1136/bmjopen-2022-065927
eng
2,023
3
7
2,023
3
7
[OBJECTIVES] To describe prevalence of chronic kidney disease (CKD), demographic and clinical characteristics, treatment patterns and rates of cardiovascular and renal complications for patients with type 2 diabetes (T2D) treated in routine clinical care. [DESIGN] Repeat cross-sectional study (6 monthly cross-sections)...
Adult nephrology; DIABETES & ENDOCRINOLOGY; Diabetic nephropathy & vascular disease; EPIDEMIOLOGY; NEPHROLOGY
0.971
176
Medicine
Medicine
2,023
36,882,145
Complete genome sequence and antimicrobial resistance analysis of ESBL-producing Shigella sonnei carrying small cryptic plasmids isolated in northern Italy.
Journal of global antimicrobial resistance
J Glob Antimicrob Resist
33
null
10.1016/j.jgar.2023.02.015
eng
2,023
6
null
2,023
3
5
[OBJECTIVES] Herein, we sequenced and assembled the genome of a Shigella sonnei isolate carrying several small plasmids using a hybrid approach that combined Oxford Nanopore Technologies and Illumina platforms. [METHODS] Whole-genome sequencing was conducted using the Illumina iSeq 100 and Oxford Nanopore MinION system...
Enterobacterales; Multidrug resistance; cryptic plasmids; hybrid approach
0.88
55
Immunology; Immunology and Allergy; Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,023
36,882,032
Graduate Medical Education in the Military Health System: Strategic Analysis and Options.
Military medicine
Mil Med
188
Suppl 1
10.1093/milmed/usac325
eng
2,023
3
6
null
null
null
[INTRODUCTION] At the request of then-Assistant Secretary of Defense for Health Affairs, Dr. Jonathan Woodson, Defense Health Horizons (DHH) examined options for shaping Graduate Medical Education (GME) in the Military Health System (MHS) in order to achieve the goals of a medically ready force and a ready medical forc...
null
0.5
83
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,023
36,881,602
Structural, programmatic, and sociocultural intersectionality of gender influencing access-uptake of reproductive, maternal, and child health services in developing regions of Ethiopia: A qualitative study.
PloS one
PLoS One
18
3
10.1371/journal.pone.0282711
eng
2,023
null
null
2,023
3
7
[BACKGROUND] Gender remains a critical social factor in reproductive, maternal, and child health and family planning (RMNCH/FP) care. However, its intersectionality with other social determinants of the RMNCH remains poorly documented. This study aimed to explore the influence of gender intersectionality on the access ...
null
0.839
467
Multidisciplinary
Multidisciplinary
2,023
36,881,354
Open-source navigation system for tracking dissociated parts with multi-registration.
International journal of computer assisted radiology and surgery
Int J Comput Assist Radiol Surg
18
12
10.1007/s11548-023-02853-x
eng
2,023
12
null
2,023
3
7
[PURPOSE] During reconstructive surgery, knee and hip replacements, and orthognathic surgery, small misalignments in the pose of prosthesis and bones can lead to severe complications. Hence, the translational and angular accuracies are critical. However, traditional image-based surgical navigation lacks orientation dat...
Bone alignment; Error analysis; Motion tracking; Multiple registration; Navigation
0.853
71
Computer Graphics and Computer-Aided Design; Radiology, Nuclear Medicine and Imaging; Surgery; Biomedical Engineering; Computer Science Applications; Computer Vision and Pattern Recognition; Health Informatics; Medicine
Computer Science; Engineering; Medicine
2,023
36,881,115
Development, implementation, and results of a simulation-based hands-on brachytherapy workshop for medical students.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Strahlenther Onkol
199
4
10.1007/s00066-023-02058-w
eng
2,023
4
null
2,023
3
7
[PURPOSE] The new Medical Licensing Regulations 2025 (Ärztliche Approbationsordnung, ÄApprO) require the development of competence-oriented teaching formats. In addition, there is a great need for high-quality teaching in the field of radiation oncology, which manifests itself already during medical school. For this re...
Accelerated partial breast irradiation; Early-stage breast cancer; Medical education; Multicatheter brachytherapy; Simulation-based training
0.907
81
Radiology, Nuclear Medicine and Imaging; Oncology
Medicine
2,023
36,881,080
Carbon-ion Radiotherapy for Inoperable Solitary Fibrous Tumor of the Skull Base: A Case Report.
In vivo (Athens, Greece)
In Vivo
37
2
10.21873/invivo.13161
eng
2,023
null
null
null
null
null
[BACKGROUND/AIM] The curative treatment for solitary fibrous tumors (SFTs) consists of surgery. However, surgery for SFTs in the skull base is difficult due to the anatomy and curative surgery may not be possible. Carbon-ion radiotherapy (C-ion RT) might be useful in the treatment of inoperable SFTs in the skull base b...
Carbon-ion radiotherapy; petrous bone; radiotherapy; skull base; solitary fibrous tumor
null
null
null
null
null
36,880,758
Modified Frailty Index Identifies Increased Risk of Postoperative Complications in Geriatric Patients After Open Reduction Internal Fixation for Distal Radius and Ulna Fractures: Analysis of 5654 Geriatric Patients, From the 2005 to 2017 the National Surgical Quality Improvement Project Database.
Annals of plastic surgery
Ann Plast Surg
90
5S Suppl 3
10.1097/SAP.0000000000003398
eng
2,023
5
1
2,023
3
4
[BACKGROUND] Open reduction internal fixation (ORIF) of distal radius and ulnar fractures (DRUFs) is one of the most common fracture surgeries for hand surgeons. Few studies have evaluated how frailty contributes to outcomes in geriatric hand surgery patients. This study hypothesizes that geriatric patients scoring hig...
null
0.688
112
Surgery
Medicine
2,023
36,880,389
Early-Life Cardiovascular Risk Factor Trajectories and Vascular Aging in Midlife: A 30-Year Prospective Cohort Study.
Hypertension (Dallas, Tex. : 1979)
Hypertension
80
5
10.1161/HYPERTENSIONAHA.122.20518
eng
2,023
5
null
2,023
3
7
[BACKGROUND] Vascular aging, as assessed by structural and functional arterial properties, is an independent predictor of cardiovascular outcomes. We aimed to explore the associations of individual cardiovascular risk factors from childhood to midlife and their accumulation over a 30-year span with vascular aging in mi...
adolescent; aging; body mass index; cardiovascular diseases; hypertension
2.827
307
Internal Medicine
Medicine
2,023
36,880,313
Expanding the Immunophenotypic Spectrum of Neoplastic and Reactive Plasmacytoid Dendritic Cells.
American journal of clinical pathology
Am J Clin Pathol
159
5
10.1093/ajcp/aqac174
eng
2,023
5
2
null
null
null
[OBJECTIVES] Targeted therapies for blastic plasmacytoid dendritic cell neoplasm (BPDCN) have presented a diagnostic dilemma for differentiating residual BPDCN from reactive plasmacytoid dendritic cells (pDCs) because these conditions have a similar immunoprofile, necessitating discovery of additional diagnostic marker...
Blastic plasmacytoid dendritic cell neoplasm; Immunohistochemistry; Minimal/measurable residual disease; Plasmacytoid dendritic cells; SOX4
0.775
146
Pathology and Forensic Medicine; Medicine
Medicine
2,023
36,879,665
Validation of Fitbit Inspire 2[TM] Against Polysomnography in Adults Considering Adaptation for Use.
Nature and science of sleep
Nat Sci Sleep
15
null
10.2147/NSS.S391802
eng
2,023
null
null
2,023
2
28
[PURPOSE] The commercialization of sleep activity tracking devices has made it possible to manage sleep quality at home. However, it is necessary to verify the reliability and accuracy of wearable devices through comparison with polysomnography (PSG), which is the standard for tracking sleep activity. This study aimed ...
polysomnography; sleep; tracking; validation study; wearable
0.956
55
Applied Psychology; Behavioral Neuroscience
Neuroscience; Psychology
2,023
36,879,619
Association of Mitral Regurgitation with Postoperative Atrial Fibrillation in Critically Ill Noncardiac Surgery Patients: A Prospective Cohort Study.
International journal of general medicine
Int J Gen Med
16
null
10.2147/IJGM.S400122
eng
2,023
null
null
2,023
2
28
[PURPOSE] Atrial fibrillation (AF) is common in critically ill patients and can have serious consequences. Postoperative AF (POAF) in critically ill patients following noncardiac surgery has been understudied, contrary to cardiac procedures. Mitral regurgitation (MR) is associated with left ventricular dysfunction, whi...
critically ill patients; mitral regurgitation; postoperative atrial fibrillation; predictive nomogram
null
null
null
null
null
36,879,567
MiRNA-23a-5p is the biomarkers for gouty arthritis and promotes inflammation in rats of gouty arthritis via MyD88/NF-κB pathway by induction TLR2.
Archives of rheumatology
Arch Rheumatol
37
4
10.46497/ArchRheumatol.2022.9236
eng
2,022
12
null
2,022
7
29
[OBJECTIVES] In this study, we aimed to examine the efficacy of micro ribonucleic acid (miRNA)-23a-5p in gouty arthritis and to investigate its possible mechanism. [MATERIALS AND METHODS] Gouty arthritis in rat was established by intraarticular injection of 0.2 mL monosodium urate crystal (20 mg/mL) inside knee joint c...
Gouty arthritis; MyD88; TLR2.; inflammation; miRNA-23a-5p
0.281
22
Rheumatology
Medicine
2,022
36,879,489
"It's all my fault": a qualitative study of how heterosexual couples experience living with vulvodynia.
Acta obstetricia et gynecologica Scandinavica
Acta Obstet Gynecol Scand
102
10
10.1111/aogs.14537
eng
2,023
10
null
2,023
3
6
[INTRODUCTION] Vulvodynia, a chronic genital pain disorder with a high lifetime prevalence among women, has a significant negative impact on both women and their partners. Although there is a growing body of literature on the experiences of women with vulvodynia, there has been little research on the condition's implic...
chronic pain; endurance; fear-avoidance; heterosexual couples; qualitative study; vulvodynia
1.384
126
Medicine; Obstetrics and Gynecology
Medicine
2,023
36,879,343
Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors.
BMC chemistry
BMC Chem
17
1
10.1186/s13065-023-00924-3
eng
2,023
3
6
2,023
3
6
[BACKGROUND] Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades. [OBJECTIVES] This study aimed to design and synthesize a novel series of methoxyphenyl thiazole carboxamide derivatives and evaluate their cyclooxygenase (COX) suppressa...
COX; HCT116; Molecular docking; NSAIDs; Thiazole
null
null
null
null
null
36,879,212
Multi-level integrative analysis of the roles of lncRNAs and differential mRNAs in the progression of chronic pancreatitis to pancreatic ductal adenocarcinoma.
BMC genomics
BMC Genomics
24
1
10.1186/s12864-023-09209-4
eng
2,023
3
6
2,023
3
6
[BACKGROUND] Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors and approximately 5% of patients with chronic pancreatitis (CP) inevitably develop PDAC. This study aims explore the key gene regulation involved in the progression of CP to PDAC, with a particular emphasis on the function of lncRN...
Chronic pancreatitis; Pancreatic ductal adenocarcinoma; WGCNA; ceRNAs; lncRNA
1.047
208
Biotechnology; Genetics
Biochemistry, Genetics and Molecular Biology
2,023
36,879,176
Impact of Bacteria Types on the Clinical Outcomes of Spontaneous Bacterial Peritonitis.
Digestive diseases and sciences
Dig Dis Sci
68
5
10.1007/s10620-023-07867-8
eng
2,023
5
null
2,023
3
7
[BACKGROUND AND AIMS] Cirrhotic patients presenting with spontaneous bacterial peritonitis (SBP) have elevated risk of short-term mortality. While high Model for End-Stage Liver Disease-Sodium score (MELD-Na) and ascites culture yielding multi-drug resistance (MDR) bacteria are well established risk factors for further...
Klebsiella pneumonia; Liver transplantation; Mortality; Spontaneous bacterial peritonitis; Streptococcus
1.068
146
Gastroenterology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,878,870
Lactobacillus rhamnosus GG alleviates colitis caused by chemotherapy via biofilm formation.
Journal of gastroenterology and hepatology
J Gastroenterol Hepatol
38
7
10.1111/jgh.16164
eng
2,023
7
null
2,023
3
23
[BACKGROUND AND AIM] Severe colitis is a common side effect of chemotherapy in cancer patients. In this study, we attempted to enhance the viability of probiotics in a gastric acid environment and improve the colitis induced by dextran sulfate sodium (DSS) and docetaxel. [METHODS] We purified Lactobacillus from yogurt ...
Biofilm; Breast cancer; Chemotherapy; Colitis; Docetaxel; LGG; Lactobacillus; Lung metastasis; Tight junction
1.179
156
Gastroenterology; Hepatology
Medicine
2,023
36,878,441
1.5-Stage Versus 2-Stage Exchange Total Hip Arthroplasty for Chronic Periprosthetic Joint Infections: A Comparison of Survivorships, Reinfections, and Patient-Reported Outcomes.
The Journal of arthroplasty
J Arthroplasty
38
7S
10.1016/j.arth.2023.02.072
eng
2,023
7
null
2,023
3
5
[BACKGROUND] Management of periprosthetic joint infection after total hip arthroplasty (THA) has traditionally consisted of a 2-stage approach. However, 1.5-stage exchange has garnered recent interest. We compared 1.5-stage to 2-stage exchange recipients. Specifically, we assessed (1) infection-free survivorship and ri...
1.5-stage; 2-stage; exchange; periprosthetic joint infections; total hip arthroplasty
1.849
171
Orthopedics and Sports Medicine
Medicine
2,023
36,878,180
Inferior mesenteric vein preserving lymphadenectomy in high left segmental colectomy for splenic flexure melanoma: A case report.
International journal of surgery case reports
Int J Surg Case Rep
104
null
10.1016/j.ijscr.2023.107956
eng
2,023
3
null
2,023
3
2
[INTRODUCTION AND IMPORTANCE] Surgical resection is the mainstay for management of splenic flexure cancers, with the aim of achieving adequate lymphadenectomy. Left-sided bowel resections often require ligation of the inferior mesenteric vein (IMV) for mesocolic dissection or lymphadenectomy which can result in congest...
Cancer; Colectomy; Inferior mesenteric vein; Melanoma; Splenic flexure
0.227
31
Surgery
Medicine
2,023
36,877,985
Maximum Phonation Time as a Surrogate Marker for Airway Clearance Physiologic Capacity and Pulmonary Function in Individuals With Amyotrophic Lateral Sclerosis.
Journal of speech, language, and hearing research : JSLHR
J Speech Lang Hear Res
66
4
10.1044/2022_JSLHR-22-00522
eng
2,023
4
12
2,023
3
6
[PURPOSE] The increased use of telehealth practices has created a critical need for home-based surrogate markers for prognostic respiratory indicators of disease progression in persons with amyotrophic lateral sclerosis (pALS). Given that phonation relies on the respiratory subsystem of speech production, we aimed to e...
null
0.827
164
Linguistics and Language; Speech and Hearing; Medicine
Health Professions; Medicine; Social Sciences
2,023
36,877,817
Four year practice effects on the RBANS in a longitudinal study of older adults.
Applied neuropsychology. Adult
Appl Neuropsychol Adult
32
2
10.1080/23279095.2023.2180361
eng
2,025
null
null
2,023
3
6
[OBJECTIVE] The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a widely used measure in neuropsychological assessment. Studies of practice effects on the RBANS have typically been assessed over one or two repeated assessments. The aim of the current study is to examine practice effects ac...
Practice effects; aging; assessment
null
null
null
null
null
36,877,746
Short Fasciotomy-Deep Inferior Epigastric Perforator Flap Harvest for Breast Reconstruction.
Plastic and reconstructive surgery
Plast Reconstr Surg
152
6
10.1097/PRS.0000000000010382
eng
2,023
12
1
2,023
3
7
[BACKGROUND] Despite several technical modifications to further reduce donor invasiveness in harvesting deep inferior epigastric perforator (DIEP) flaps, techniques with general applicability and demonstrating clinical benefits are scarce. The present study aimed to introduce a short-fasciotomy technique and evaluate i...
null
1.302
220
Surgery
Medicine
2,023
36,877,729
Epidemiology, management and outcomes of Cryptococcus gattii infections: A 22-year cohort.
PLoS neglected tropical diseases
PLoS Negl Trop Dis
17
3
10.1371/journal.pntd.0011162
eng
2,023
3
null
2,023
3
6
[BACKGROUND] Cryptococcus gattii is a globally endemic pathogen causing disease in apparently immune-competent hosts. We describe a 22-year cohort study from Australia's Northern Territory to evaluate trends in epidemiology and management, and outcome predictors. [METHODS] A retrospective cohort study of all C. gattii ...
null
1.258
172
Infectious Diseases; Pharmacology, Toxicology and Pharmaceutics; Public Health, Environmental and Occupational Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,877,711
Differences in infection and prevention of HIV and other sexually transmitted infections among older adults in Columbus, Ohio.
PloS one
PLoS One
18
3
10.1371/journal.pone.0282702
eng
2,023
null
null
2,023
3
6
[INTRODUCTION] In the United States, rates of sexually transmitted infections (STIs) have increased year after year for the past six consecutive years. Even so, the majority of research has focused on younger populations with little work examining infections and prevention methods among older adults. [METHODS] Data com...
null
0.839
467
Multidisciplinary
Multidisciplinary
2,023
36,877,686
Determinants of early initiation of first antenatal care visit in Ethiopia based on the 2019 Ethiopia mini-demographic and health survey: A multilevel analysis.
PloS one
PLoS One
18
3
10.1371/journal.pone.0281038
eng
2,023
null
null
2,023
3
6
[BACKGROUND] Early initiation of the first antenatal care visit provides a critical opportunity for health promotion, disease prevention, and curative care for women and their unborn fetuses. However, in developing countries, including Ethiopia, it is underutilized and most of the pregnant women didn't attend antenatal...
null
0.839
467
Multidisciplinary
Multidisciplinary
2,023
36,876,701
The perspective of pharmacist on pharmacovigilance and adverse drug reaction reporting in Asir region, Saudi Arabia.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
27
4
10.26355/eurrev_202302_31410
eng
2,023
2
null
null
null
null
[OBJECTIVE] Adverse drug reactions (ADRs) are widespread worldwide, and their intervention is critical to patient safety and healthcare quality. Pharmacists are essential in monitoring and reporting ADRs, directly influencing patient care. This study aimed to examine the prevalence of ADRs among pharmacists and their k...
null
null
null
null
null
null
36,876,686
Extra-auditory effects of noise exposure in school workers and preventive measures: a systematic review.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
27
4
10.26355/eurrev_202302_31386
eng
2,023
2
null
null
null
null
[OBJECTIVE] Noise is still today one of the main causes of occupational diseases; in fact, in Italy in the three-year period 2019-2022, hearing loss represented 15% of all occupational diseases recognized by the National Institute for Insurance against Accidents at Work. The extra-auditory effects related to noise expo...
null
null
null
null
null
null
36,876,613
Sexual experiences of infertile women: A qualitative study.
Nigerian journal of clinical practice
Niger J Clin Pract
26
2
10.4103/njcp.njcp_651_22
eng
2,023
2
null
null
null
null
[BACKGROUND] It is suggested that stress related to infertility causes marriage conflicts and decreases in the frequency of sexual intercourse. [AIM] This study aimed to explore the experiences of the sexuality of infertile women. [PATIENTS AND METHODS] A phenomenological design was used in this study. We conducted fac...
Experience; infertility; sexuality; women
0.27
39
Medicine
Medicine
2,023
36,876,159
Association between endometrial thickness before ovulation, live birth, and placenta previa rates in clomiphene citrate-treated cycles.
AJOG global reports
AJOG Glob Rep
3
1
10.1016/j.xagr.2023.100161
eng
2,023
2
null
2,023
1
18
[BACKGROUND] Although a recent study reported that the pregnancy outcomes in the first trimester were more correlated with endometrial thickness on the day of the trigger than with endometrial thickness on the day of single fresh-cleaved embryo transfer, it remains unclear whether endometrial thickness on the day of th...
clomiphene citrate; endometrial thickness; live birth; placenta previa; proliferative phase; single embryo transfer
0.496
11
Obstetrics and Gynecology
Medicine
2,023
36,875,985
Advanced Platelet-rich Fibrin-mediated Regeneration of Necrotic Immature Permanent Teeth: A Clinico-radiographic Observational Study.
International journal of clinical pediatric dentistry
Int J Clin Pediatr Dent
15
4
10.5005/jp-journals-10005-2408
eng
2,022
null
null
null
null
null
[AIM] The objective of the study was to assess the regenerative potential of advanced platelet-rich fibrin (APRF) in the regenerative treatment of necrotic immature permanent teeth (NIPT) in the maxillary incisor region. [STUDY DESIGN] After institutional review board clearance, 10 children aged between 8 and 14 years ...
Advanced platelet-rich fibrin; Immature permanent teeth; Necrotic pulp; Open apex; Pediatric dentistry; Regenerative endodontic treatment
0.223
18
Oral Surgery; Orthodontics; Pediatrics, Perinatology and Child Health; Periodontics
Dentistry; Medicine
2,022
36,875,708
Profiling the low-beta characteristics of the subthalamic nucleus in early- and late-onset Parkinson's disease.
Frontiers in aging neuroscience
Front Aging Neurosci
15
null
10.3389/fnagi.2023.1114466
eng
2,023
null
null
2,023
2
16
[OBJECTIVES] Low-beta oscillation (13-20 Hz) has rarely been studied in patients with early-onset Parkinson's disease (EOPD, age of onset ≤50 years). We aimed to explore the characteristics of low-beta oscillation in the subthalamic nucleus (STN) of patients with EOPD and investigate the differences between EOPD and la...
aging; local field potential; microelectrode recording; subthalamic nucleus
1.173
135
Aging; Cognitive Neuroscience
Biochemistry, Genetics and Molecular Biology; Neuroscience
2,023
36,875,499
Thymoquinone ameliorates acrylamide-induced reproductive toxicity in female rats: An experimental study.
International journal of reproductive biomedicine
Int J Reprod Biomed
21
1
10.18502/ijrm.v21i1.12668
eng
2,023
1
null
2,023
2
8
[BACKGROUND] Acrylamide (AA) is a carcinogenic compound that causes severe reproductive impairments and represents a high environmental risk factor. Thymoquinone (TQ) has a unique antioxidant activity and has been widely used as a protective agent against various types of toxicity. [OBJECTIVE] To evaluate the protectiv...
Cyclooxygenase 2; Inflammation.; Oxidative stress; Rats; Thymoquinone; Acrylamide
0.382
48
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,023
36,875,358
Cardiorespiratory fitness, body mass index, cardiovascular disease, and mortality in young men: A cohort study.
Frontiers in public health
Front Public Health
11
null
10.3389/fpubh.2023.1076065
eng
2,023
null
null
2,023
2
15
[OBJECTIVE] We examined the association between cardiorespiratory fitness (CRF), body mass index (BMI), incidence of major acute cardiovascular events (MACE), and all-cause mortality (ACM). [METHODS] We conducted a retrospective cohort study involving 212,631 healthy young men aged 16 to 25 years who had undergone medi...
Asian; all-cause mortality; body mass index; cardiorespiratory fitness; major acute cardiovascular event; young men
0.895
119
Public Health, Environmental and Occupational Health
Medicine
2,023
36,875,339
Histological evaluation of the effects of bone morphogenetic protein 9 and angiopoietin 1 on bone healing.
Journal of Taibah University Medical Sciences
J Taibah Univ Med Sci
18
5
10.1016/j.jtumed.2023.02.005
eng
2,023
10
null
2,023
2
16
[OBJECTIVES] Bone healing remains a critical clinical orthopedic problem. Bone, which is a greatly vascularized tissue, depends on the tight temporal and spatial link between blood vessels and bone cells. Thus, angiogenesis is crucial for skeletal growth and bone fracture healing. The purpose of this study was to evalu...
Angiogenesis; Angiopoietin 1; Bone morphogenetic protein 9; Osteogenesis
0.449
37
Medicine
Medicine
2,023
36,875,305
NSCLC Patients Achieving Long-term Progression-free Survival With Docetaxel Plus Ramucirumab: A Retrospective Study.
Cancer diagnosis prognosis
Cancer Diagn Progn
3
2
10.21873/cdp.10204
eng
2,023
null
null
2,023
3
3
[BACKGROUND/AIM] The antineoplastic drug docetaxel (DOC) and the antivascular endothelial growth factor inhibitor ramucirumab (RAM) are widely used in combination for second or later-line regimens for advanced non-small cell lung cancer (NSCLC). While the median progression-free survival (PFS) of DOC+RAM has been repor...
Non-small cell lung cancer; docetaxel; long-term; progression-free survival; ramucirumab
null
null
null
null
null
36,874,735
Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Acute Kidney Injury in Children With Shock: A Prospective Study.
Cureus
Cureus
15
1
10.7759/cureus.34407
eng
2,023
1
null
2,023
1
30
[BACKGROUND] The current definition of acute kidney injury (AKI) is based on serum creatinine (SrCr) and urine output, limited by delayed identification of such patients. Plasma neutrophil gelatinase-associated lipocalin (NGAL) is considered an early diagnostic and highly predictive biomarker of AKI. [OBJECTIVE] To det...
acute kidney injury; neutrophil gelatinase-associated lipocalin; pediatric intensive care unit; serum creatinine; shock
null
null
null
null
null