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37,875,848
Distinct effects of Fgf7 and Fgf10 on the terminal differentiation of murine bladder urothelium revealed using an organoid culture system.
BMC urology
BMC Urol
23
1
10.1186/s12894-023-01338-y
eng
2,023
10
24
2,023
10
24
[BACKGROUND] Dysregulation of the terminal differentiation of bladder urothelium is associated with the pathogenesis of urinary tract disorders. Fibroblast growth factor (Fgf)7 and Fgf10 stimulate urothelial proliferation; however, their roles in cellular differentiation remain unclear. In this study, we used an organo...
Bladder; Differentiation; Fibroblast growth factor 10; Fibroblast growth factor 7; Organoid; Urothelium
0.609
57
Medicine; Reproductive Medicine; Urology
Medicine
2,023
37,875,834
BMP7 alleviates trigeminal neuralgia by reducing oligodendrocyte apoptosis and demyelination.
The journal of headache and pain
J Headache Pain
24
1
10.1186/s10194-023-01681-3
eng
2,023
10
24
2,023
10
24
[BACKGROUND] BMP7 has been shown to have neuroprotective effects and to alleviate demyelination. However, its role in trigeminal neuralgia (TN) has not been well investigated. The current study aims to determine whether BMP7 plays a role in demyelination, its effects on pain behaviors and mechanism of action in rats wi...
Apoptosis; BMP7; Demyelination; Oligodendrocytes; Trigeminal neuralgia
1.791
97
Anesthesiology and Pain Medicine; Medicine; Neurology
Medicine
2,023
37,875,726
Life satisfaction for adolescents with developmental and behavioral disabilities during the COVID-19 pandemic.
Pediatric research
Pediatr Res
95
3
10.1038/s41390-023-02852-3
eng
2,024
2
null
2,023
10
24
[BACKGROUND] This study aimed to identify contextual factors associated with life satisfaction during the COVID-19 pandemic for adolescents with mental, emotional, behavioral, and developmental (MEBD) disabilities. [METHODS] Data were collected from a sample of 1084 adolescents aged 11-21 years from April 2020 to Augus...
null
1.171
176
Pediatrics, Perinatology and Child Health
Medicine
2,024
37,875,696
A nonrandomized controlled trial: long-term outcomes of LATG/LAPG for cStage I gastric cancer: Japan Clinical Oncology Group Study JCOG1401.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Gastric Cancer
27
1
10.1007/s10120-023-01432-y
eng
2,024
1
null
2,023
10
25
[BACKGROUND] A previous report confirmed the safety of laparoscopy-assisted total and proximal gastrectomies (LATG and LAPG) (JCOG1401). This report demonstrates the 5-year relapse-free survival (RFS) and overall survival (OS) after long-term follow-up to confirm the efficacy of these surgical methods as key secondary ...
Gastric cancer; Laparoscopy-assisted proximal gastrectomy; Laparoscopy-assisted total gastrectomy; Long-term survival; cStage I
2.489
106
Cancer Research; Gastroenterology; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,875,354
Identification of biomarkers in laryngeal cancer by weighted gene co-expression network analysis.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Zhong Nan Da Xue Xue Bao Yi Xue Ban
48
8
10.11817/j.issn.1672-7347.2023.220630
eng
2,023
8
28
null
null
null
[OBJECTIVES] Laryngeal cancer (LC) is a globally prevalent and highly lethal tumor. Despite extensive efforts, the underlying mechanisms of LC remain inadequately understood. This study aims to conduct an innovative bioinformatic analysis to identify hub genes that could potentially serve as biomarkers or therapeutic t...
co-expression gene modules; gene biomarker; laryngeal cancer; weighted gene co-expression network analysis
null
null
null
null
null
37,875,291
Dose-response effects of resistance training on physical function in frail older Chinese adults: A randomized controlled trial.
Journal of cachexia, sarcopenia and muscle
J Cachexia Sarcopenia Muscle
14
6
10.1002/jcsm.13359
eng
2,023
12
null
2,023
10
24
[BACKGROUND] Effective exercise for the frail elderly has been found to contribute to healthy aging; the corresponding relationship between intensity and volume of exercise and health effects remains unclear. The present study aimed to investigate the dose-response effects of resistance training on muscle strength and ...
dose-response; frailty; muscle strength; older adults; physical fitness; resistance training; volume and intensity
2.816
112
Orthopedics and Sports Medicine; Physiology
Medicine
2,023
37,874,041
Multicentre, prospective, randomized control non-inferiority trial of bladder catheter management in colon surgery.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Colorectal Dis
25
7
10.1111/codi.16593
eng
2,023
7
null
2,023
5
9
[AIM] Perioperative bladder catheterization is a controversial issue. Most current recommendations are based on data from open surgery extrapolated to enhanced recovery after surgery or fast-track programmes ranging between 24 and 48 h. The aim of this study is to provide a rationale for reducing catheterization time w...
acute urine retention; bladder catheter; laparoscopic colon
1.164
110
Gastroenterology
Medicine
2,023
37,873,928
Mechanical thrombectomy in low Alberta stroke program early CT score (ASPECTS) in hyperacute stroke-a systematic review and meta-analysis.
The British journal of radiology
Br J Radiol
96
1152
10.1259/bjr.20230084
eng
2,023
12
null
2,023
10
24
[OBJECTIVE] Major randomized controlled trials of mechanical thrombectomy (MT) for acute ischemic stroke (AIS) failed to include a substantial number of patients presenting with low baseline Alberta Stroke Program Early CT Score (ASPECTS:0-5). Patients experiencing hyperacute strokes (last known well ≤ 6 h) can potenti...
null
0.812
128
Radiology, Nuclear Medicine and Imaging; Medicine
Medicine
2,023
37,873,643
Development of Stable CHO-K1 Cell Lines Overexpressing Full-Length Human CD20 Antigen.
Iranian biomedical journal
Iran Biomed J
27
5
10.61186/ibj.27.5.269
eng
2,023
9
1
2,023
7
8
[BACKGROUND] CD20 is a differentiation-related antigen exclusively expressed on the membrane of B lymphocytes. CD20 amplification is observed in numerous immune-related disorders, making it an ideal target for immunotherapy of hematological malignancies and autoimmune diseases. MAb-based therapies targeting CD20 have a...
CD20; CHO cells; Immunotherapy; Lentiviral vector
0.347
42
Biochemistry, Genetics and Molecular Biology; Biochemistry; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,873,485
Mast-Cell Expressed Membrane Protein-1 (MCEMP1) is expressed in classical monocytes and alveolar macrophages in Idiopathic Pulmonary Fibrosis and regulates cell chemotaxis, adhesion, and migration in a TGFβ dependent manner.
bioRxiv : the preprint server for biology
bioRxiv
null
null
10.1101/2023.10.07.561349
eng
2,023
10
10
2,023
10
10
[BACKGROUND] Mast-Cell Expressed Membrane Protein-1 (MCEMP1) is higher in Idiopathic Pulmonary Fibrosis (IPF) patients with increased risk of death and poor outcomes. Here we seek to establish the mechanistic role of MCEMP1 in pulmonary fibrosis. [METHODS] MCEMP1 expression was analyzed by single-cell RNA sequencing, i...
null
null
null
null
null
null
37,873,378
Interplay Of Serum Bilirubin and Tobacco Smoking with Lung and Head and Neck Cancers in a Diverse, EHR-linked Los Angeles Biobank.
medRxiv : the preprint server for health sciences
medRxiv
null
null
10.1101/2023.09.29.23296364
eng
2,023
10
3
2,023
10
3
[BACKGROUND] Bilirubin is a potent antioxidant with a protective role in many diseases. We examined the relationships between serum bilirubin (SB) levels, tobacco smoking (a known cause of low SB), and aerodigestive cancers, grouped as lung (LC) and head and neck (HNC). [METHODS] We examined the associations between SB...
null
null
null
null
null
null
37,873,024
Perceptions and Preoccupations of Patients and Physicians Regarding Use of Medical Cannabis as an Intervention Against Chronic Musculoskeletal Pain: Results from a Qualitative Study.
Journal of pain research
J Pain Res
16
null
10.2147/JPR.S413450
eng
2,023
null
null
2,023
10
18
[OBJECTIVE] Explore perceptions and preoccupations regarding use of medical cannabis against chronic musculoskeletal pain, among patients and physicians. [DESIGN] Qualitative study using interviews with patients and physicians, based on the Theory of Planned Behavior (TPB). [SETTING] The study was conducted in Quebec, ...
chronic musculoskeletal pain; lack of knowledge; medical cannabis; qualitative study; stigma; theory of planned behavior
0.699
77
Anesthesiology and Pain Medicine
Medicine
2,023
37,872,952
Association between sports expertise and visual attention in male and female soccer players.
PeerJ
PeerJ
11
null
10.7717/peerj.16286
eng
2,023
null
null
2,023
10
19
[BACKGROUND] Visual attention plays a crucial role in daily living and in sports, affecting an athlete's performance and thus, potentially, the outcome of a match. However, studies assessing the association between the level of sports expertise and visual attention have yielded mixed results. This study was conducted t...
Expertise; Multiple object tracking; Sex difference; Visual attention; Soccer player
0.623
124
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,023
37,871,861
Lower Revision Rates and Improved Stability With a Monoblock Ceramic Acetabular Cup.
The Journal of arthroplasty
J Arthroplasty
39
4
10.1016/j.arth.2023.10.032
eng
2,024
4
null
2,023
10
21
[BACKGROUND] Monoblock ceramic cups are designed to accommodate large-diameter femoral heads. This has the potential to offer the advantages of an increased range of motion and enhanced joint stability. These features could benefit younger and high-demand patients in need of total hip arthroplasty. The aim of this stud...
bearings; ceramic-on-ceramic; dislocation; large-diameter femoral head; monoblock acetabular component; total hip arthroplasty
1.951
171
Orthopedics and Sports Medicine
Medicine
2,024
37,871,833
Partition Dosimetry and Outcomes of Metastatic Neuroendocrine Tumors after Yttrium-90 Resin Microsphere Radioembolization.
Journal of vascular and interventional radiology : JVIR
J Vasc Interv Radiol
35
5
10.1016/j.jvir.2023.10.015
eng
2,024
5
null
2,023
10
21
[PURPOSE] To characterize estimated mean tumor-absorbed dose (ADT) and objective response of metastatic neuroendocrine tumor (NET) after resin microsphere yttrium-90 ([90]Y) hepatic radioembolization using partition dosimetry. [MATERIALS AND METHODS] In this retrospective, single-center study, multicompartment dosimetr...
null
0.646
150
Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
37,871,625
Aldehyde dehydrogenase 2 gene rs671 GA polymorphism is associated with an increased risk of digestive tract cancer.
The Journal of international medical research
J Int Med Res
51
10
10.1177/03000605231206257
eng
2,023
10
null
null
null
null
[OBJECTIVE] Acetaldehyde can accumulate in cells and form acetaldehyde-DNA adducts that result in digestive tract cancer development. Acetaldehyde dehydrogenase 2 (ALDH2) enzymatic activity is involved in this process. Here, we aimed to analyze the relationship between an ALDH2 gene polymorphism and the digestive tract...
Aldehyde dehydrogenase 2; Hakka; biomarker; digestive tract cancer; gene polymorphism; genotype
0.445
74
Biochemistry; Biochemistry; Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,871,567
Multiple sclerosis functional tests and their comparability with self-administered values: A pilot study.
Biomedica : revista del Instituto Nacional de Salud
Biomedica
43
3
10.7705/biomedica.6873
eng
2,023
9
30
2,023
9
30
[INTRODUCTION] Neurological impairment in multiple sclerosis is highly variable among patients and over time it is difficult to quantify. The Multiple Sclerosis Outcome Assessment Consortium established sensitive, cost-effective, clinically significant, and reproducible measures of different functional systems to measu...
Multiple sclerosis; telemonitoring; self-testing; disability evaluation; reference values
null
null
null
null
null
37,871,495
Trauma Laparotomy for the Cirrhotic Patient: An Outcome-Based Analysis.
The Journal of surgical research
J Surg Res
294
null
10.1016/j.jss.2023.09.008
eng
2,024
2
null
2,023
10
21
[INTRODUCTION] There is a lack of large-scale data on outcomes of cirrhotic patients undergoing trauma laparotomy. We aimed to compare outcomes of cirrhotic versus noncirrhotic trauma patients undergoing laparotomy. [METHODS] We analyzed 2018 American College of Surgeons Trauma Quality Improvement Program. We included ...
Cirrhosis; Laparotomy; Trauma
0.736
131
Surgery
Medicine
2,024
37,871,279
The Association Between Family Resources and Language Among Young Children Who are Deaf and Hard of Hearing.
Journal of developmental and behavioral pediatrics : JDBP
J Dev Behav Pediatr
44
9
10.1097/DBP.0000000000001225
eng
2,023
12
1
2,023
10
23
[OBJECTIVE] Our study (1) examined demographic factors in families with children with bilateral hearing loss and how they relate to Family Resource Scale (FRS) questionnaire data and (2) examined correlations between FRS data and measures of language. [METHODS] Children aged 6 months to 10 years with bilateral hearing ...
null
null
null
null
null
null
37,871,008
Prevalence and public health significance of rabies virus in bats in the North Region of Cameroon.
PLoS neglected tropical diseases
PLoS Negl Trop Dis
17
10
10.1371/journal.pntd.0010803
eng
2,023
10
null
2,023
10
23
[BACKGROUND] Rabies is a zoonotic disease of all warm-blooded animals including humans. There is a paucity of data on the status of rabies in wild animals in Cameroon and the disease is endemic in the country with dogs being the main source of transmission. Bat habitats are widespread in Cameroon, but there is limited ...
null
1.258
172
Infectious Diseases; Pharmacology, Toxicology and Pharmaceutics; Public Health, Environmental and Occupational Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
37,870,968
Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C.
The New England journal of medicine
N Engl J Med
389
23
10.1056/NEJMoa2308795
eng
2,023
12
7
2,023
10
22
[BACKGROUND] KRAS G12C is a mutation that occurs in approximately 3 to 4% of patients with metastatic colorectal cancer. Monotherapy with KRAS G12C inhibitors has yielded only modest efficacy. Combining the KRAS G12C inhibitor sotorasib with panitumumab, an epidermal growth factor receptor (EGFR) inhibitor, may be an e...
null
20.544
1,231
Medicine
Medicine
2,023
37,870,834
Hypertension Diagnosis, Treatment, and Control in India.
JAMA network open
JAMA Netw Open
6
10
10.1001/jamanetworkopen.2023.39098
eng
2,023
10
2
2,023
10
2
[IMPORTANCE] Hypertension is a major cause of morbidity and mortality worldwide. Previous efforts to characterize gaps in the hypertension care continuum-including diagnosis, treatment, and control-in India did not assess district-level variation. Local data are critical for planning, implementation, and monitoring eff...
null
3.478
154
Medicine
Medicine
2,023
37,870,777
Objective and subjective sleep patterns and biomarkers of stress among women with a history of sexual abuse in childhood.
Psychological trauma : theory, research, practice and policy
Psychol Trauma
16
Suppl 1
10.1037/tra0001600
eng
2,024
4
null
2,023
10
23
[OBJECTIVE] Childhood sexual abuse (CSA) is associated with posttraumatic stress symptoms (PTSSs) and sleep disturbance into adulthood. The latter is thought to emerge from dysregulation in biobehavioral systems, including nighttime hyperarousal; however, studies investigating specific mechanisms to explain these long-...
null
1.173
86
Clinical Psychology; Social Psychology
Psychology
2,024
37,870,618
Socioeconomic factors associated with poor medication adherence in patients with type 2 diabetes.
European journal of clinical pharmacology
Eur J Clin Pharmacol
80
1
10.1007/s00228-023-03571-8
eng
2,024
1
null
2,023
10
23
[PURPOSE] This study aims to determine initiation and persistence for patients with type 2 diabetes receiving their first prescription of an antidiabetic agent and the associations with socioeconomic factors. [METHODS] A cohort study including 8515 patients with type 2 diabetes who were prescribed their first antidiabe...
Discontinuation; Hypoglycemic agents; Medication adherence; Persistence; Socioeconomic disparities in Health
0.849
126
Medicine; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
37,869,155
Development and validation of an artificial intelligence-powered acne grading system incorporating lesion identification.
Frontiers in medicine
Front Med (Lausanne)
10
null
10.3389/fmed.2023.1255704
eng
2,023
null
null
2,023
10
6
[BACKGROUND] The management of acne requires the consideration of its severity; however, a universally adopted evaluation system for clinical practice is lacking. Artificial intelligence (AI) evaluation systems hold the promise of enhancing the efficiency and reproducibility of assessments. Artificial intelligence (AI)...
acne; acne lesions; artificial intelligence; dermatology; grading system
0.909
102
Medicine
Medicine
2,023
37,869,133
Fabry disease and sleep disorders: a systematic review.
Frontiers in neurology
Front Neurol
14
null
10.3389/fneur.2023.1217618
eng
2,023
null
null
2,023
10
5
[BACKGROUND] Fabry disease (FD) is an X-chromosome-linked disorder characterized by a reduced or complete absence of the enzyme α-galactosidase, resulting in the accumulation of lysosomal globotriaosylceramide. Despite the presence of these deposits in multiple organs, the problem of sleep disorders within this populat...
Fabry disease (FD); central sleep apnea (CSA); excessive daytime sleepiness (EDS); obstructive sleep apnea (OSA); sleep disorders
0.966
118
Neurology; Neurology
Medicine; Neuroscience
2,023
37,868,912
The Challenge of Choosing the Right Stimulation Target for Dystonic Tremor-A Series of Instructive Cases.
Movement disorders clinical practice
Mov Disord Clin Pract
10
10
10.1002/mdc3.13846
eng
2,023
10
null
2,023
8
22
[BACKGROUND] Thalamic deep brain stimulation (DBS) is established for medically refractory tremor syndromes and globus pallidus stimulation (GPi-DBS) for medically refractory dystonia syndromes. For combined tremor and dystonia syndromes, the best target is unclear. [OBJECTIVES] We present four patients with two differ...
dystonia; dystonic tremor; thalamic/pallidal deep brain stimulation
0.731
42
Neurology; Neurology
Medicine; Neuroscience
2,023
37,868,861
Is preoperative intracranial hemorrhage a surgical contraindication in infective endocarditis with stroke?
Journal of thoracic disease
J Thorac Dis
15
9
10.21037/jtd-23-695
eng
2,023
9
28
2,023
8
30
[BACKGROUND] The optimal timing for surgery in infective endocarditis (IE) with hemorrhagic stroke and neurologic deficits is difficult to decide because of the risk of exacerbating the stroke and provoking intracranial hemorrhagic conversion after surgery using cardiopulmonary bypass (CPB). This retrospective study ai...
Infective endocarditis (IE); intracranial hemorrhage (ICH); stroke
0.651
95
Pulmonary and Respiratory Medicine
Medicine
2,023
37,868,849
Transesophageal endoscopic ultrasound with bronchoscope-guided fine-needle aspiration for diagnostic and staging purposes: a narrative review.
Journal of thoracic disease
J Thorac Dis
15
9
10.21037/jtd-23-681
eng
2,023
9
28
2,023
8
21
[BACKGROUND AND OBJECTIVE] Transesophageal endoscopic ultrasound with bronchoscope-guided fine-needle aspiration (EUS-B-FNA) is a feasible and well-tolerated modality that is increasingly used to diagnose intrathoracic lesions. This narrative review summarizes the current application of EUS-B-FNA for diagnosing lung ca...
lung cancer; sarcoidosis
0.651
95
Pulmonary and Respiratory Medicine
Medicine
2,023
37,868,803
Magnitude of Visual Acuity Change with ETDRS versus Snellen Testing in Clinical Trials: Implications for Clinic-Based Outcomes.
Ophthalmology science
Ophthalmol Sci
4
2
10.1016/j.xops.2023.100372
eng
2,024
null
null
2,023
7
19
[PURPOSE] To compare visual acuity (VA) changes using standardized ETDRS best-corrected visual acuity (BCVA) and nonstandardized Snellen VA among subjects enrolled in clinical trials. [DESIGN] Retrospective study. [PARTICIPANTS] Patients enrolled in prospective clinical trials at 3 urban retina practices. [METHODS] Bes...
Clinical trial; ETDRS; Snellen; Visual acuity change
1.91
20
Ophthalmology
Medicine
2,024
37,868,801
Epidemiology of Angioid Streaks and Pseudoxanthoma Elasticum (2011-2020): A Nationwide Population-based Cohort Study.
Ophthalmology science
Ophthalmol Sci
4
2
10.1016/j.xops.2023.100370
eng
2,024
null
null
2,023
7
20
[PURPOSE] We aimed to describe the epidemiology of angioid streaks (AS) and pseudoxanthoma elasticum (PXE), which are rare diseases, using a national claims database. [DESIGN] This was a population-based longitudinal cohort study. [PARTICIPANTS] A total of 126 million individuals were covered by the universal health co...
Angioid streaks; Epidemiology; Incidence; Prevalence; Pseudoxanthoma elasticum
1.91
20
Ophthalmology
Medicine
2,024
37,868,394
Autologous Whole-Blood Versus Corticosteroid Local Injection in Treatment of Plantar Fasciitis: A Randomized Single Blind Placebo-Controlled Study.
Cureus
Cureus
15
9
10.7759/cureus.45588
eng
2,023
9
null
2,023
9
20
[BACKGROUND] Autologous whole-blood intralesional injection has attracted interest as a possible means of treatment for chronic plantar fasciitis. We contrasted its effectiveness with that of corticosteroids, which have a longer history of success in treating tendinopathies such as plantar fasciitis. In order to monito...
autologous whole-blood; corticosteroid; methylprednisolone; placebo; plantar fascitis; visual analog scale
null
null
null
null
null
37,867,853
Comparison of ventilation techniques for compensation of mask leakage using a ventilator and a regular full-face mask: A bench study.
Heliyon
Heliyon
9
10
10.1016/j.heliyon.2023.e20546
eng
2,023
10
null
2,023
9
29
[BACKGROUND] The use of noninvasive ventilation (NIV) during and after extubation is common. We designed this study to determine the optimal strategy to compensate for mask leaks and achieve effective ventilation during NIV by comparing commonly used operating room ventilator systems and a regular facemask. [METHODS] W...
Mask leak; Mask ventilation; Non-invasive ventilation; Ventilator
0.617
115
Multidisciplinary
Multidisciplinary
2,023
37,867,593
Predominance of Trichophyton tonsurans causing tinea capitis: A 12-year retrospective study in the north of Iran.
Current medical mycology
Curr Med Mycol
9
1
10.18502/CMM.2023.345026.1395
eng
2,023
3
null
null
null
null
[BACKGROUND AND PURPOSE] Among different clinical entities of dermatophytosis, tinea capitis (TC) is considered a major public health challenge in the world, especially in regions with poor health and low income. Therefore, this study aimed to provide a retrospective analysis of the patients suspected of TC who were re...
Iran; Prevalence; Tinea capitis; Trichophyton tonsurans
null
null
null
null
null
37,867,492
Long-term impact of post COVID-19 pandemic quarantine on eating habits changes among adult residents of Riyadh, Saudi Arabia.
Frontiers in nutrition
Front Nutr
10
null
10.3389/fnut.2023.1243288
eng
2,023
null
null
2,023
10
5
[BACKGROUND] COVID-19 outbreak and quarantine measures clearly had an impact on the population's eating habits-related behavior. [OBJECTIVE] This study aimed to explore the long-term impact of the COVID-19 pandemic and physical quarantine on eating habits after quarantine among Riyadh city residents, Saudi Arabia. [MET...
COVID-19 pandemic; Saudi Arabia; dietary changes; healthy/unhealthy; impact; long-term
0.828
94
Food Science; Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Agricultural and Biological Sciences; Medicine; Nursing
2,023
37,867,369
Diabetic severity and oncological outcomes of colorectal cancer following curative resection: A population-based cohort study in Taiwan.
Cancer
Cancer
129
24
10.1002/cncr.34975
eng
2,023
12
15
2,023
10
23
[BACKGROUND] Although diabetes is a poor prognostic factor for colorectal cancer (CRC), whether diabetes severity provides an additional predictive value for CRC prognosis remains unclear. The study aimed to investigate the prognostic differences after curative CRC resection among patients with different diabetic sever...
colorectal cancer; diabetes mellitus; diabetes with complication; disease-free survival; overall survival
2.887
349
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,867,359
Associated factors in pediatric patients admitted with severe iron-deficiency anemia in the last seven years - the experience of a single pediatric unit.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Rom J Morphol Embryol
64
3
10.47162/RJME.64.3.13
eng
2,023
null
null
null
null
null
[OBJECTIVES] To study the causes of iron deficiency, laboratory findings and clinical manifestation of infants aged 6-12 months and children aged 1-3 years diagnosed with severe iron-deficiency anemia. [PATIENTS, MATERIALS AND METHODS] We conducted an observational, retrospective single tertiary center study between Ja...
null
null
null
null
null
null
37,867,355
A cases series of endovascular and microsurgical combined treatment of intracranial aneurysms.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Rom J Morphol Embryol
64
3
10.47162/RJME.64.3.09
eng
2,023
null
null
null
null
null
[OBJECTIVE] Our scientific paper is aimed at describing multimodal treatment of intracranial aneurysms represented by microsurgery and endovascular therapy. [PATIENTS, MATERIALS AND METHODS] We report four cases of intracranial aneurysms treated in our Department of Neurosurgery by microsurgery (clipping) and endovascu...
null
null
null
null
null
null
37,867,354
Preliminary study of some of the main intratumor stroma components in gastric carcinomas.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Rom J Morphol Embryol
64
3
10.47162/RJME.64.3.08
eng
2,023
null
null
null
null
null
[AIM] The relationship between stromal compartment and tumor behavior in gastric carcinomas is still poorly understood and defined. Therefore, the authors started, with this preliminary study, an analysis of stromal compartment morphology and behavior in tumors arising from gastric mucosa epithelium. [MATERIALS AND MET...
null
null
null
null
null
null
37,867,253
Dermoscopic findings and comparison of usefulness of longitudinal versus transversal sections in the histological diagnosis of alopecia X.
Veterinary dermatology
Vet Dermatol
35
2
10.1111/vde.13212
eng
2,024
4
null
2,023
10
22
[BACKGROUND] A combination of dermoscopic and histological findings may provide useful information for the diagnosis of hair follicle diseases. However, there are no studies on dermoscopic-histopathological correlations in dogs affected by alopecia X, and comparison of longitudinal versus transversal sectioning of skin...
alopecia X; dermoscopic evaluation; transversal sections
0.725
74
Veterinary
Veterinary
2,024
37,867,183
Inhibition of thioredoxin-1 enhances the toxicity of glycolysis inhibitor 2-deoxyglucose by downregulating SLC1A5 expression in colorectal cancer cells.
Cellular oncology (Dordrecht, Netherlands)
Cell Oncol (Dordr)
47
2
10.1007/s13402-023-00887-6
eng
2,024
4
null
2,023
10
23
[BACKGROUND] Targeting glycolysis in cancer is an attractive approach for therapeutic intervention. 2-Deoxyglucose (2DG) is a synthetic glucose analog that inhibits glycolysis. However, its efficacy is limited by the systemic toxicity at high doses. Understanding the mechanism of 2DG resistance is important for further...
2-deoxyglucose; Colorectal cancer; Glycolysis; SLC1A5; Thioredoxin-1
1.573
62
Medicine; Molecular Medicine; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,867,042
Coronary Artery Calcium Identified on Non-Gated Chest CT Scans: A Wasted Opportunity for Preventive Cardiological Care.
Heart, lung circulation
Heart Lung Circ
32
11
10.1016/j.hlc.2023.09.016
eng
2,023
11
null
2,023
10
20
[BACKGROUND] Coronary artery calcium (CAC) evaluated on dedicated cardiac computed tomography (CT) is an independent predictor of cardiovascular events. This study aimed to evaluate the correlation between CAC detected on non-gated standard chest CT and coronary lesions on coronary angiography (CAG) and determine its i...
Computed tomography; Coronary angiography; Coronary artery calcium; Coronary disease; Risk stratification
null
null
null
null
null
37,867,011
Anxiety Change After Dopamine Therapy in Parkinson Disease is Independent of Motor Improvement.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Am J Geriatr Psychiatry
32
2
10.1016/j.jagp.2023.09.001
eng
2,024
2
null
2,023
9
10
[BACKGROUND] Several anxiety syndromes have been associated with Parkinson disease (PD), but their interactions with dopamine replacement therapy (DRT) and motor function dynamics are not completely understood. We sought to delineate how DRT impacts anxiety phenomenology in PD and whether these changes are dissociable ...
null
1.378
150
Geriatrics and Gerontology; Psychiatry and Mental Health
Medicine
2,024
37,867,003
Short-Term and Long-Term Effects of Ischemic Conditioning on Liver Transplantation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Transplantation proceedings
Transplant Proc
55
9
10.1016/j.transproceed.2023.08.012
eng
2,023
11
null
2,023
10
20
[BACKGROUND] Although liver transplantation (LT) is one of the definitive treatments for patients with end-stage liver failure, it inevitably results in ischemic reperfusion injury. It is known that prognosis is improved when temporary ischemic conditioning (IC) is applied to patients with ischemic reperfusion injury. ...
null
0.318
93
Surgery; Transplantation
Medicine
2,023
37,866,774
ERAS Cardiac Society turnkey order set for patient blood management: Proceedings from the AATS ERAS Conclave 2023.
The Journal of thoracic and cardiovascular surgery
J Thorac Cardiovasc Surg
168
3
10.1016/j.jtcvs.2023.10.034
eng
2,024
9
null
2,023
10
20
[OBJECTIVES] There are multiple published guidelines on comprehensive patient blood management (PBM), centered on the 3 pillars of PBM: managing preoperative anemia, minimizing blood loss, and tolerating intraoperative/postoperative anemia. We sought to create an order set to facilitate widespread implementation of evi...
critical care; enhanced recovery after surgery; patient blood management; perioperative care; transfusion
1.932
225
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,024
37,866,456
Safety and efficacy of eblasakimab, an interleukin 13 receptor α1 monoclonal antibody, in adults with moderate-to-severe atopic dermatitis: A phase 1b, multiple-ascending dose study.
Journal of the American Academy of Dermatology
J Am Acad Dermatol
90
3
10.1016/j.jaad.2023.10.026
eng
2,024
3
null
2,023
10
20
[BACKGROUND] Eblasakimab, an interleukin (IL)-13 receptor α1 antagonist, blocks IL-4 and IL-13 signaling through the type 2 receptor. [OBJECTIVE] The safety and efficacy of eblasakimab was evaluated in adults with moderate-to-severe atopic dermatitis (AD). [METHODS] In this phase 1b randomized, double-blinded study, 52...
EASI; IL-13; IL-4; atopic dermatitis; eblasakimab; moderate-to-severe AD; pruritus; type 2 inflammation
1.315
256
Dermatology
Medicine
2,024
37,866,300
A comparison of the practice patterns of emergency department teams that include physicians, nurse practitioners, or physician assistants.
Nursing outlook
Nurs Outlook
71
6
10.1016/j.outlook.2023.102062
eng
2,023
null
null
2,023
10
20
[BACKGROUND] Physicians see most emergency department (ED) patients, but, recently, nurse practitioners (NPs) and physician assistants (PAs) have provided an increasing amount of ED care. [PURPOSE] Compare NP and PA teams' practice patterns to physician teams in EDs. [METHODS] Using 12 years of data from the National H...
Advanced practice nursing; Emergency services; Health services; Health workforce; Hospital; Nurse practitioners; Research
1.065
76
Nursing
Nursing
2,023
37,866,248
Application of the International Classification of Cognitive Disorders in Epilepsy (IC-CoDE) to frontal lobe epilepsy using multicenter data.
Epilepsy behavior : EB
Epilepsy Behav
148
null
10.1016/j.yebeh.2023.109471
eng
2,023
11
null
2,023
10
20
[RATIONALE] The International Classification of Cognitive Disorders in Epilepsy (IC-CoDE) was recently introduced as a consensus-based, empirically-driven taxonomy of cognitive disorders in epilepsy and has been effectively applied to patients with temporal lobe epilepsy (TLE). The purpose of this study was to apply th...
Cognition; Epilepsy; Frontal lobe epilepsy; Neuropsychology; Phenotypes
null
null
null
null
null
37,866,126
Enlightening the path to NSCLC biomarkers: Utilizing the power of XAI-guided deep learning.
Computer methods and programs in biomedicine
Comput Methods Programs Biomed
243
null
10.1016/j.cmpb.2023.107864
eng
2,024
1
null
2,023
10
20
[BACKGROUND AND OBJECTIVE] The early diagnosis of Non-small cell lung cancer (NSCLC) is of prime importance to improve the patient's survivability and quality of life. Being a heterogeneous disease at the molecular and cellular level, the biomarkers responsible for the heterogeneity aid in distinguishing NSCLC into its...
Biomarkers; Classification; DNA methylation; Druggability; Explainable AI; Non-small cell lung cancer
1.13
150
Computer Science Applications; Health Informatics; Software
Computer Science; Medicine
2,024
37,865,767
Relatives' experiences of care encounters in the general ward after ICU discharge: a qualitative study.
BMC nursing
BMC Nurs
22
1
10.1186/s12912-023-01562-9
eng
2,023
10
21
2,023
10
21
[BACKGROUND] Care encounters at general wards have many reasons, and the complexity differs. Some arriving at the ward are relatives of discharged intensive care unit patients', who are usually more fragile than others due to what had happened to them. Research indicates that care encounters leave relatives dissatisfie...
Care encounter; Family care; Life-changing events; Nursing care; Quality of care; Relatives; Transitional care
0.894
62
Nursing
Nursing
2,023
37,865,625
PVA/PVP Nanofibres Incorporated with Ecklonia cava Phlorotannins Exhibit Excellent Cytocompatibility and Accelerate Hyperglycaemic Wound Healing.
Tissue engineering and regenerative medicine
Tissue Eng Regen Med
21
2
10.1007/s13770-023-00590-5
eng
2,024
2
null
2,023
10
21
[BACKGROUND] Diabetic foot ulcer (DFU) is a major debilitating complication of diabetes. The lack of effective diabetic wound dressings has been a significant problem in DFU management. In this study, we aim to establish a phlorotannin-incorporated nanofibre system and determine its potential in accelerating hyperglyca...
Diabetic foot ulcer; Drug delivery; Ecklonia cava phlorotannins; Hyperglycaemic wound healing; Nanofibres
0.978
43
Biomedical Engineering; Medicine
Engineering; Medicine
2,024
37,865,347
Electrodermal activity in bipolar disorder: Differences between mood episodes and clinical remission using a wearable device in a real-world clinical setting.
Journal of affective disorders
J Affect Disord
345
null
10.1016/j.jad.2023.10.125
eng
2,024
1
15
2,023
10
21
[BACKGROUND] Bipolar disorder (BD) lacks objective measures for illness activity and treatment response. Electrodermal activity (EDA) is a quantitative measure of autonomic function, which is altered in manic and depressive episodes. We aimed to explore differences in EDA (1) inter-individually: between patients with B...
Biomarker; Bipolar disorder; Depression; Electrodermal activity; Mania; Treatment response
2.121
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
37,865,343
Discovery of depression-associated factors among childhood trauma victims from a large sample size: Using machine learning and network analysis.
Journal of affective disorders
J Affect Disord
345
null
10.1016/j.jad.2023.10.101
eng
2,024
1
15
2,023
10
20
[BACKGROUND] Experiences of childhood trauma (CT) would lead to serious mental problems, especially depression. Therefore, it becomes crucial to identify influential factors related to depression and explore their associations. The objectives were to 1) identify critical depression-related factors using the extreme gra...
Childhood trauma; Depression; Machine learning; Network analysis
2.121
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
37,865,184
The effects of time-restricted eating versus habitual diet on inflammatory cytokines and adipokines in the general adult population: a systematic review with meta-analysis.
The American journal of clinical nutrition
Am J Clin Nutr
119
1
10.1016/j.ajcnut.2023.10.009
eng
2,024
1
null
2,023
10
20
[BACKGROUND] Time-restricted eating (TRE) may facilitate weight loss, but its impact on inflammation remains unclear. Chronic inflammation can detrimentally increase risk of obesity-associated comorbidities. [OBJECTIVES] The aim of this systematic review was to synthesize and determine the effects of TRE on cytokine an...
adipokines; cytokines; inflammation; time-restricted eating
2.111
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
37,865,004
Machine Learning-Based Integration Develops a Macrophage-Related Index for Predicting Prognosis and Immunotherapy Response in Lung Adenocarcinoma.
Archives of medical research
Arch Med Res
54
7
10.1016/j.arcmed.2023.102897
eng
2,023
11
null
2,023
10
19
[BACKGROUND] Macrophages play a critical role in tumor immune microenvironment (TIME) formation and cancer progression in lung adenocarcinoma (LUAD). However, few studies have comprehensively and systematically described the characteristics of macrophages in LUAD. [METHODS] This study identified macrophage-related mark...
Immunotherapy; Lung adenocarcinoma; Machine learning; Macrophage; Prognostic signature
1.076
100
Medicine
Medicine
2,023
37,864,816
Does diabetes mellitus affect the development of fetal brain structures and spaces including corpus callosum, subarachnoid space, insula, and parieto-occipital fissure?
Journal of clinical ultrasound : JCU
J Clin Ultrasound
51
9
10.1002/jcu.23597
eng
2,023
null
null
2,023
10
21
[PURPOSE] We investigated the impact of pregestational and gestational diabetes mellitus (PGDM and GDM) on the development of fetal intracranial structures and spaces. [METHODS] This prospective cross-sectional study involved singleton pregnancies between 20 and 32 weeks of gestation. The study comprised a control grou...
fetal brain; gestational diabetes mellitus; neurosonography; pregestational diabetes mellitus
0.305
69
Radiology, Nuclear Medicine and Imaging
Medicine
2,023
37,864,717
Identification and management of subclinical disease activity in early multiple sclerosis: a review.
Journal of neurology
J Neurol
271
4
10.1007/s00415-023-12021-5
eng
2,024
4
null
2,023
10
21
[IMPORTANCE] Early treatment initiation in multiple sclerosis (MS) is crucial in preventing irreversible neurological damage and disability progression. The current assessment of disease activity relies on relapse rates and magnetic resonance imaging (MRI) lesion activity, but inclusion of other early, often "hidden," ...
Biomarkers; Cognition; Disease activity; Fatigue; High-efficacy therapy; Multiple sclerosis
1.687
168
Neurology; Neurology
Medicine; Neuroscience
2,024
37,864,661
The toxic profile of tramadol combined with nicotine on the liver and testicles: evidence from endoplasmic reticulum stress.
Molecular biology reports
Mol Biol Rep
50
12
10.1007/s11033-023-08903-6
eng
2,023
12
null
2,023
10
21
[BACKGROUND] Tramadol is one of the most commonly abused substances in the Middle East. Furthermore, smoking is extremely common among the population. [METHODS] An experimental study was performed on Sprague-Dawley rats to explore the effects of both nicotine and tramadol on the liver and testes. The tramadol was admin...
BIB; CHOP; Endoplasmic reticulum stress; Liver; Nicotine; Testis; Tramadol
0.649
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,864,631
Digestive cancer surgery in low-mid income countries: analysis of postoperative mortality and complications in a single-center study.
Langenbeck's archives of surgery
Langenbecks Arch Surg
408
1
10.1007/s00423-023-03156-0
eng
2,023
10
21
2,023
10
21
[PURPOSE] This study aimed to analyze postoperative and 90-day morbidity and mortality and their risk factors in all digestive cancer curative intent resections of a single digestive surgical department in a low-mid income country. [METHODS] All consecutive patients who underwent a surgical resection for digestive canc...
Curative surgery; Digestive cancer; Morbidity; Mortality; Risk factors
0.758
94
Surgery
Medicine
2,023
37,864,593
Exploring the association of glioma tumor residuals from incongruent [[18]F]FET PET/MR imaging with tumor proliferation using a multiparametric MRI radiomics nomogram.
European journal of nuclear medicine and molecular imaging
Eur J Nucl Med Mol Imaging
51
3
10.1007/s00259-023-06468-x
eng
2,024
2
null
2,023
10
21
[PURPOSE] The study aimed to using multiparametric MRI radiomics to predict glioma tumor residuals (TRFET over MR) derived from incongruent [[18]F]fluoroethyl-L-tyrosine ([[18]F]FET) PET/MR imaging. [METHODS] One hundred ten patients with gliomas who underwent [[18]F]FET PET/MR scanning were retrospectively analyzed. T...
Gliomas; PET/MR; Radiomics; Tumor proliferation; [18F]FET
2.392
192
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
37,864,267
GHB: a life-threatening drug complications and outcome of GHB detoxification treatment-an observational clinical study.
Addiction science clinical practice
Addict Sci Clin Pract
18
1
10.1186/s13722-023-00414-w
eng
2,023
10
21
2,023
10
21
[BACKGROUND] GHB (gammahydroxybutyrate) and its precursors are popular recreational drugs due to their sedative, anxiolytic and sexually stimulating effects. Their use has been steadily increasing in recent years. The detoxification process is complex and prone to high rates of complications while little is known about...
Delirium; Detoxification; GHB; Intensive care unit
null
null
null
null
null
37,864,245
The provision of malaria services in border districts of four countries in Southern Africa: results from a cross-sectional community assessment of malaria border health posts.
Malaria journal
Malar J
22
1
10.1186/s12936-023-04687-z
eng
2,023
10
20
2,023
10
20
[BACKGROUND] The importation of parasites across borders remains a threat to malaria elimination. The Southern African Development Community Malaria Elimination Eight (E8) established 39 border health facilities on 5 key international borders between high and low-burden countries. These clinics aimed to improve access ...
Border health post; Elimination; KAP; Malaria
1.105
126
Infectious Diseases; Parasitology
Immunology and Microbiology; Medicine
2,023
37,864,203
Geospatial disparities and predictors of anaemia among pregnant women in Sub-Saharan Africa.
BMC pregnancy and childbirth
BMC Pregnancy Childbirth
23
1
10.1186/s12884-023-06008-3
eng
2,023
10
20
2,023
10
20
[BACKGROUND] Anaemia has become a major public health concern among women in Sub-Saharan Africa (SSA). However, little is known about the spatial disparities in anaemia prevalence and their associated factors among pregnant women in the region. This study analysed the spatial disparities in anaemia and their associated...
Anaemia; Geospatial; Pregnant women; Sub-Saharan Africa
1.057
122
Obstetrics and Gynecology
Medicine
2,023
37,864,196
ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer.
Journal of experimental clinical cancer research : CR
J Exp Clin Cancer Res
42
1
10.1186/s13046-023-02834-7
eng
2,023
10
20
2,023
10
20
[BACKGROUND] Tumor cells can resist chemotherapy-induced pyroptosis through glycolytic reprogramming. Estrogen-related receptor alpha (ERRα) is a central regulator of cellular energy metabolism associated with poor cancer prognosis. Herein, we refine the oncogenic role of ERRα in the pyroptosis pathway and glycolytic m...
Cisplatin resistance; Endometrial cancer; Metabolic reprogramming; Pyroptosis
null
null
null
null
null
37,863,847
A multi-institutional study to predict the benefits of DEB-TACE and molecular targeted agent sequential therapy in unresectable hepatocellular carcinoma using a radiological-clinical nomogram.
La Radiologia medica
Radiol Med
129
1
10.1007/s11547-023-01736-0
eng
2,024
1
null
2,023
10
20
[OBJECTIVE] Exploring the efficacy of a Radiological-Clinical (Rad-Clinical) model in predicting prognosis of unresectable hepatocellular carcinoma (HCC) patients after drug eluting beads transcatheter arterial chemoembolization (DEB-TACE) to optimize the targeted sequential treatment. [METHODS] In this retrospective a...
DEB-TACE; Hepatocellular carcinoma; Progression-free survival; Radiomics score; Targeted therapy
null
null
null
null
null
37,863,421
Artificial intelligence in osteoarthritis detection: A systematic review and meta-analysis.
Osteoarthritis and cartilage
Osteoarthritis Cartilage
32
3
10.1016/j.joca.2023.09.011
eng
2,024
3
null
2,023
10
18
[OBJECTIVES] As an increasing number of studies apply artificial intelligence (AI) algorithms in osteoarthritis (OA) detection, we performed a systematic review and meta-analysis to pool the data on diagnostic performance metrics of AI, and to compare them with clinicians' performance. [MATERIALS AND METHODS] A search ...
Artificial intelligence; Deep learning; Machine learning; Osteoarthritis; Systematic review and meta-analysis
2.331
197
Biomedical Engineering; Orthopedics and Sports Medicine; Rheumatology
Engineering; Medicine
2,024
37,863,305
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Experimental neurology
Exp Neurol
371
null
10.1016/j.expneurol.2023.114577
eng
2,024
1
null
2,023
10
18
[BACKGROUND] Early brain injury (EBI) refers to a severe brain injury that occurs within hours to days after subarachnoid hemorrhage (SAH). Neuronal damage in EBI is considered a key factor leading to poor prognosis. Currently, our understanding of the mechanisms of neuronal damage, such as neuronal autophagy, is still...
Autophagy; Glyceraldehyde-3-phosphate dehydrogenase; Subarachnoid hemorrhage
1.499
212
Developmental Neuroscience; Neurology
Neuroscience
2,024
37,863,243
Anchoring fins of fully covered self-expandable metal stents affect pull-out force and stent migration.
Gastrointestinal endoscopy
Gastrointest Endosc
99
3
10.1016/j.gie.2023.10.036
eng
2,024
3
null
2,023
10
18
[BACKGROUND AND AIMS] Stent migration and subsequent adverse events are frequently observed in the use of fully covered self-expandable metal stents (FCSEMSs) for distal biliary stenosis. In this study, we identified predictors for stent migration based on biomechanical stent characteristics and associated these findin...
null
2.018
236
Gastroenterology; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
37,862,928
Maternal and perinatal outcomes in primiparous singleton pregnancies conceived with assisted reproductive technology in British Columbia.
European journal of obstetrics, gynecology, and reproductive biology
Eur J Obstet Gynecol Reprod Biol
291
null
10.1016/j.ejogrb.2023.10.010
eng
2,023
12
null
2,023
10
18
[OBJECTIVE] To evaluate the odds of developing adverse maternal and perinatal outcomes in primiparous singleton pregnancies conceived with assisted reproductive technology (ART) compared with pregnancies conceived without ART. [STUDY DESIGN] A retrospective population-based cohort study using data from the British Colu...
ART; Assisted reproductive technologies; Maternal complications; Neonatal complications; Primiparity; Singleton pregnancy; Spontaneous conception
null
null
null
null
null
37,862,858
Using blastocyst re-expansion rate for deciding when to warm a new blastocyst for single vitrified-warmed blastocyst transfer.
Reproductive biomedicine online
Reprod Biomed Online
47
6
10.1016/j.rbmo.2023.103378
eng
2,023
12
null
2,023
9
3
[RESEARCH QUESTION] Can predictive post-warm parameters that support the decision to transfer a warmed blastocyst or to warm another blastocyst be identified in women with multiple frozen-vitrified blastocysts? [DESIGN] Retrospective single-centre observational cohort analysis. A total of 1092 single vitrified-warmed b...
live birth; re-expansion; single blastocyst transfer; time-lapse; vitrification
1.214
139
Developmental Biology; Obstetrics and Gynecology; Reproductive Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,862,368
Longitudinal changes in tear cytokines and antimicrobial proteins in trachomatous disease.
PLoS neglected tropical diseases
PLoS Negl Trop Dis
17
10
10.1371/journal.pntd.0011689
eng
2,023
10
null
2,023
10
20
[BACKGROUND] Trachoma is a neglected tropical disease caused by ocular infection with Chlamydia trachomatis, where repeated infections and chronic inflammation can ultimately result in scarring, trichiasis and blindness. While scarring is thought to be mediated by a dysregulated immune response, the kinetics of cytokin...
null
1.258
172
Infectious Diseases; Pharmacology, Toxicology and Pharmaceutics; Public Health, Environmental and Occupational Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
37,862,101
Digital Marker for Early Screening of Mild Cognitive Impairment Through Hand and Eye Movement Analysis in Virtual Reality Using Machine Learning: First Validation Study.
Journal of medical Internet research
J Med Internet Res
25
null
10.2196/48093
eng
2,023
10
20
2,023
10
20
[BACKGROUND] With the global rise in Alzheimer disease (AD), early screening for mild cognitive impairment (MCI), which is a preclinical stage of AD, is of paramount importance. Although biomarkers such as cerebrospinal fluid amyloid level and magnetic resonance imaging have been studied, they have limitations, such as...
Alzheimer disease; biomarkers; dementia; digital markers; eye movement; hand movement; machine learning; mild cognitive impairment; screening; virtual reality
2.02
214
Health Informatics
Medicine
2,023
37,861,978
Dual-energy CT improves differentiation of non-hypervascular pancreatic neuroendocrine neoplasms from CA 19-9-negative pancreatic ductal adenocarcinomas.
La Radiologia medica
Radiol Med
129
1
10.1007/s11547-023-01733-3
eng
2,024
1
null
2,023
10
20
[PURPOSE] To evaluate the utility of dual-energy CT (DECT) in differentiating non-hypervascular pancreatic neuroendocrine neoplasms (PNENs) from pancreatic ductal adenocarcinomas (PDACs) with negative carbohydrate antigen 19-9 (CA 19-9). [METHODS] This retrospective study included 26 and 39 patients with pathologically...
Dual-energy scanned projection; Multidetector computed tomography; Neuroendocrine tumours; Pancreatic ductal carcinoma
null
null
null
null
null
37,922,092
Androgen-induced upregulation of CFTR in pancreatic β-cell contributes to hyperinsulinemia in PCOS model.
Endocrine
Endocrine
83
1
10.1007/s12020-023-03516-2
eng
2,024
1
null
2,023
11
3
[PURPOSE] Polycystic ovarian syndrome (PCOS) is an endocrine-metabolic condition affecting 5-10% of reproductive-aged women and characterized by hyperandrogenism, insulin resistance (IR), and hyperinsulinemia. CFTR is known to be regulated by steroid hormones, and our previous study has demonstrated an essential role o...
Androgen; CFTR; Hyperinsulinemia; Insulin; Polycystic ovary syndrome
0.971
107
Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,921,753
Experiences and Perceptions of Healthcare Stakeholders in Disclosing Errors and Adverse Events to Historically Marginalized Patients.
Journal of patient safety
J Patient Saf
19
8
10.1097/PTS.0000000000001173
eng
2,023
12
1
2,023
10
25
[OBJECTIVES] We sought to assess the experiences and perceptions of healthcare stakeholders involved in the response to historically marginalized patients who have been harmed in healthcare. We investigated the challenges in disclosing errors and adverse events and the types of tools and resources that would better add...
null
0.739
49
Leadership and Management; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,023
37,921,679
Pharmacological Management of Cholera: A Century of Expert Opinions in Cecil Textbook of Medicine.
American journal of therapeutics
Am J Ther
30
6
10.1097/MJT.0000000000001679
eng
null
null
null
null
null
null
[BACKGROUND] Cholera is a potentially lethal diarrheal disease produced by Vibrio cholerae serotypes O1 El Tor and O139. Known since antiquity, the condition causes epidemics in many areas, particularly in Asia, Africa, and South America. Left untreated, the mortality may reach 50%. The crucial therapeutic intervention...
null
null
null
null
null
null
37,921,678
Oxygen Targets After Cardiac Arrest: A Meta-analysis of Randomized Controlled Trials.
American journal of therapeutics
Am J Ther
30
6
10.1097/MJT.0000000000001636
eng
null
null
null
2,023
8
17
[BACKGROUND] Optimal oxygen saturation target in patients resuscitated after cardiac arrest is unknown. Previous randomized controlled trials (RCTs) comparing restrictive oxygen therapy with liberal therapy have shown conflicting results. [STUDY QUESTION] We performed a meta-analysis of available RCTs to consolidate th...
null
null
null
null
null
null
37,921,677
Descemet Stripping Only: Long-Term Outcomes.
Cornea
Cornea
43
8
10.1097/ICO.0000000000003421
eng
2,024
8
1
2,023
10
31
[PURPOSE] Descemet stripping only (DSO) is a relatively novel treatment for Fuchs endothelial corneal dystrophy (FECD). In this procedure, a central area of Descemet membrane and endothelium is removed without the insertion of donor tissue. Evaluation of long-term outcomes (≥5 years) after DSO is imperative to establis...
null
0.955
141
Ophthalmology
Medicine
2,024
37,920,887
Sex-specific causality of MRI-derived body compositions on glycaemic traits: Mendelian randomization and observational study.
Diabetes, obesity & metabolism
Diabetes Obes Metab
26
1
10.1111/dom.15326
eng
2,024
1
null
2,023
11
3
[AIM] To investigate the sex-specific causality of body compositions in type 2 diabetes and related glycaemic traits using Mendelian randomization (MR). [MATERIALS AND METHODS] We leveraged sex-specific summary-level statistics from genome-wide association studies for three adipose deposits adjusted for body mass index...
Mendelian randomization; body composition; fat distribution; lean body mass; sexual dimorphism; type 2 diabetes
null
null
null
null
null
37,920,790
Evaluation of new generation systemic immune-inflammation markers to predict urine culture growth in urinary tract infection in children.
Frontiers in pediatrics
Front Pediatr
11
null
10.3389/fped.2023.1201368
eng
2,023
null
null
2,023
10
18
[OBJECTIVE] Systemic inflammation has been implicated in the development and progression of urinary tract infection (UTI). Accordingly, the aim of this study is to determine whether the white blood cell (WBC), C-reactive protein (CRP), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and systemic imm...
C-reactive protein; children; systemic immune-inflammation index; urinary tract infection
0.715
83
Pediatrics, Perinatology and Child Health
Medicine
2,023
37,920,781
Significant Systemic Insulin Resistance is Associated With Unique Glioblastoma Multiforme Phenotype.
Clinical pathology (Thousand Oaks, Ventura County, Calif.)
Clin Pathol
16
null
10.1177/2632010X231207725
eng
2,023
null
null
2,023
10
31
[BACKGROUND] Some glioblastoma multiforme (GBM) are characterized by the presence of gemistocytes (GCs), a unique phenotype of reactive astrocytes. Certain GCs can be identified as neoplastic cells but these cells were also found to be associated with diabetes in non-neoplastic lesions of the central nervous system. Ou...
Gemistocytes; diabetes; glioblastoma; insulin; metabolism
null
null
null
null
null
37,920,402
Telehealth Utilization During the COVID-19 Pandemic Among People With Functional Disabilities in the U.S.: A Preliminary Analysis of National Health Interview Survey 2020 Data.
AJPM focus
AJPM Focus
2
4
10.1016/j.focus.2023.100149
eng
2,023
12
null
2,023
9
28
[INTRODUCTION] Telehealth has been widely promoted and adopted at multiple levels in the U.S. healthcare system during the COVID-19 pandemic. However, this rapid expansion of telehealth services may have further exacerbated health inequities among marginalized groups. [METHODS] Using the 2020 National Health Interview ...
COVID-19; Telehealth; disability; pandemic
null
6
Epidemiology; Health Informatics; Public Health, Environmental and Occupational Health
Medicine
2,023
37,920,163
Successful therapy using high-dose furmonertinib for non-small cell lung cancer with leptomeningeal metastasis: a case report and literature review.
Frontiers in oncology
Front Oncol
13
null
10.3389/fonc.2023.1233198
eng
2,023
null
null
2,023
10
18
[BACKGROUND] Lung cancer is the second most common form of malignant tumor and has the highest mortality rate worldwide. Among its subtypes, lung adenocarcinoma is the most prevalent. Leptomeningeal metastasis (LM) is rare and is characterized by a dismal prognosis, with overall survival periods typically spanning 4 to...
EGFR; NSCLC; furmonertinib; leptomeningeal metastasis; target therapy
1.066
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,920,142
The hue of temporomandibular joint arthroscopy under local versus general anaesthesia.
Journal of oral rehabilitation
J Oral Rehabil
51
3
10.1111/joor.13611
eng
2,024
3
null
2,023
11
2
[BACKGROUND] Temporomandibular joint arthroscopy (TMJA) is often performed under general anaesthesia (GA) worldwide on an inpatient basis, whereas local anaesthesia (LA) is not equally considered as the standard procedure. [OBJECTIVES] To compare the efficacy between LA and GA when performing TMJA. [METHODS] This study...
arthroscopy; general anaesthesia; joint dislocation; local anesthesia; temporomandibular joint
1.116
114
Dentistry
Dentistry
2,024
37,919,891
Genome-wide association study and fine-mapping on Korean biobank to discover renal trait-associated variants.
Kidney research and clinical practice
Kidney Res Clin Pract
43
3
10.23876/j.krcp.23.079
eng
2,024
5
null
2,023
11
3
[BACKGROUND] Chronic kidney disease is a significant health burden worldwide, with increasing incidence. Although several genome- wide association studies (GWAS) have investigated single nucleotide polymorphisms (SNP) associated with kidney trait, most studies were focused on European ancestry. [METHODS] We utilized cl...
Chronic kidney disease; Estimated glomerular filtration rate; Genetics; Genome-wide association study; Korean Genome and Epidemiology
1.16
37
Nephrology; Urology
Medicine
2,024
37,919,728
An early warning precision public health approach for assessing COVID-19 vulnerability in the UK: the Moore-Hill Vulnerability Index (MHVI).
BMC public health
BMC Public Health
23
1
10.1186/s12889-023-17092-7
eng
2,023
11
2
2,023
11
2
[BACKGROUND] Most COVID-19 vulnerability indices rely on measures that are biased by rates of exposure or are retrospective like mortality rates that offer little opportunity for intervention. The Moore-Hill Vulnerability Index (MHVI) is a precision public health early warning alternative to traditional infection fatal...
Ambulance data; COVID-19; Precision public health; Vulnerability index
1.253
211
Public Health, Environmental and Occupational Health
Medicine
2,023
37,919,436
The advantages of duct-to-duct biliary reconstruction in pediatric living donor liver transplantation.
Pediatric surgery international
Pediatr Surg Int
39
1
10.1007/s00383-023-05568-x
eng
2,023
11
2
2,023
11
2
[BACKGROUND/PURPOSE] Whether Roux-en-Y hepatic jejunectomy (HJ) or duct-to-duct biliary reconstruction (DD) is more useful in pediatric living donor liver transplantation has not yet been fully investigated. Therefore, to assess the feasibility and safety of DD, we compared the surgical outcomes of DD to HJ. [METHODS] ...
Biliary complication; Gastrointestinal perforation; Liver transplantation; Pediatric
0.548
78
Medicine; Pediatrics, Perinatology and Child Health; Surgery
Medicine
2,023
37,918,885
Association between Removal of High-Frequency Oscillations and the Effect of Epilepsy Surgery: A Meta-Analysis.
Journal of neurological surgery. Part A, Central European neurosurgery
J Neurol Surg A Cent Eur Neurosurg
85
3
10.1055/a-2202-9344
eng
2,024
5
null
2,023
11
2
[BACKGROUND] High-frequency oscillations (HFOs) are spontaneous electroencephalographic (EEG) events that occur within the frequency range of 80 to 500 Hz and consist of at least four distinct oscillations that stand out from the background activity. They can be further classified into "ripples" (80-250 Hz) and "fast r...
null
null
null
null
null
null
37,918,523
Early Outcomes of Interwoven Nitinol Wire Stent Placement versus Endarterectomy for the Treatment of Atherosclerotic Disease of the Common Femoral Artery.
Journal of vascular and interventional radiology : JVIR
J Vasc Interv Radiol
35
2
10.1016/j.jvir.2023.10.024
eng
2,024
2
null
2,023
10
31
[PURPOSE] To compare the clinical outcomes of common femoral artery (CFA) atherosclerotic disease treated with either surgical endarterectomy or an interwoven nitinol wire stent system. [MATERIALS AND METHODS] A retrospective review was conducted of all patients with chronic, de novo atherosclerotic CFA disease treated...
null
0.646
150
Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
37,918,444
The Clinical Features of Late Postoperative Cholangitis After Hepaticojejunostomy Brought on by Conditions other than Cancer Recurrence.
The American surgeon
Am Surg
90
4
10.1177/00031348231212585
eng
2,024
4
null
2,023
11
2
[PURPOSE] Postoperative cholangitis and anastomotic strictures (AS) are long-term complications of biliary-enteric anastomosis (BEA). [METHODS] We retrospectively reviewed data of patients who underwent bile duct resection with or without hepatectomy and investigated the risk factors for postoperative cholangitis, beni...
biliary stenosis; complication; hepaticojejunostomy
null
null
null
null
null
37,918,370
Comparison of Different Prediction Models for Unplanned Interruption of Continuous Renal Replacement Treatment: A Systematic Review of Qualitative Analyses.
Blood purification
Blood Purif
53
2
10.1159/000534718
eng
2,024
null
null
2,023
11
2
[INTRODUCTION] This study will systematically search and evaluate the prediction models for unplanned interruption of continuous renal replacement treatment (CRRT) and to provide a reference for building a higher quality prediction model for unplanned interruption of CRRT. [METHODS] PubMed, Embase, Cochrane Library, CI...
Continuous renal replacement treatment; Prediction model; Qualitative analysis; Systematic review; Unexpected interruption; Unplanned treatment interruption
0.545
72
Medicine; Nephrology; Hematology
Medicine
2,024
37,918,363
Predictors of Developmental Defects of Enamel in Primary Maxillary Central Incisors Using Bayesian Model Selection.
Caries research
Caries Res
58
1
10.1159/000534793
eng
2,024
null
null
2,023
11
2
[INTRODUCTION] Localized non-inheritable developmental defects of tooth enamel (DDE) are classified as enamel hypoplasia (EH), opacity (OP), and post-eruptive breakdown (PEB) using the enamel defects index. To better understand the etiology of DDE, we assessed the linkages amongst exposome variables for these defects d...
Bayesian Analysis; Developmental defects of enamel; Parathyroid Hormone; Phosphorus; Vitamin D
0.771
116
Dentistry
Dentistry
2,024
37,918,175
Much ado about nothing? Discrepancy between the available data on the antiviral effect of hydroxychloroquine in March 2020 and its inclusion in COVID-19 clinical trials and outpatient prescriptions.
Public health
Public Health
225
null
10.1016/j.puhe.2023.09.018
eng
2,023
12
null
2,023
11
1
[OBJECTIVES] Many of the 2020 COVID-19 clinical trials included an (hydroxy)chloroquine ((H)CQ) arm. We aimed to juxtapose the state of science before April 2020 regarding the benefits of (H)CQ for viral infections with the number and size of the clinical trials studying (H)CQ and the volume of (H)CQ dispensed in Franc...
COVID-19; Chloroquine; Clinical trial; Health expenditure; Hydroxychloroquine; Public health; SARS-CoV-2
1.203
102
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,023
37,918,084
The effect of age on the hearing-related quality of life in normal-hearing adults.
Journal of communication disorders
J Commun Disord
106
null
10.1016/j.jcomdis.2023.106386
eng
2,023
null
null
2,023
10
27
[INTRODUCTION] Recently, a new holistic Patient Reported Outcome Measure (PROM) to assess hearing-related quality of life was developed, named the hearing-related quality of life questionnaire for Auditory-VIsual, COgnitive and Psychosocial functioning (hAVICOP). The purpose of the current study was to evaluate if the ...
Aging; Hearing; Quality of Life; Questionnaire
0.588
79
Linguistics and Language; LPN and LVN; Speech and Hearing; Cognitive Neuroscience; Experimental and Cognitive Psychology
Health Professions; Neuroscience; Nursing; Psychology; Social Sciences
2,023
37,918,057
Evaluating amikacin minimum inhibitory concentration in trailing growth for Mycobacterium avium complex.
Tuberculosis (Edinburgh, Scotland)
Tuberculosis (Edinb)
143
null
10.1016/j.tube.2023.102427
eng
2,023
12
null
2,023
10
28
[BACKGROUND] Amikacin is a first-line drug that must be evaluated when performing an antimycobacterial susceptibility test (AST) for Mycobacterium avium complex (MAC). However, the presence of sporadic trailing growth in MAC makes determining the precise point for reading its minimal inhibitory concentration (MIC) chal...
Amikacin; Minimum inhibitory concentration; Mycobacterium avium complex; Sensititre SLOMYCOI panel; Trailing growth
0.605
101
Infectious Diseases; Microbiology; Immunology; Microbiology
Immunology and Microbiology; Medicine
2,023
37,918,049
Stakeholder endorsement advancing the implementation of a patient-reported domain for harms in rheumatology clinical trials: Outcome of the OMERACT Safety Working Group.
Seminars in arthritis and rheumatism
Semin Arthritis Rheum
63
null
10.1016/j.semarthrit.2023.152288
eng
2,023
12
null
2,023
10
26
[OBJECTIVES] To develop an understanding of the concept of safety/harms experienced by patients involved in clinical trials for their rheumatic and musculoskeletal diseases (RMDs) and to seek input from the OMERACT community before moving forward to developing or selecting an outcome measurement instrument. [METHODS] O...
Adverse events; Core outcome set; Harms; OMERACT; Safety; rheumatology
1.721
139
Anesthesiology and Pain Medicine; Rheumatology
Medicine
2,023
37,918,009
Leisure and social occupational choice within nursing home facilities in Ireland: Residents perspectives.
Scandinavian journal of occupational therapy
Scand J Occup Ther
31
1
10.1080/11038128.2023.2259222
eng
2,024
1
null
2,023
11
7
[BACKGROUND] National standards for nursing homes in Ireland require that residents are offered a choice of recreational and stimulating activities to meet their needs and preferences. [AIMS/OBJECTIVES] To investigate residents' perceptions of leisure and social occupational choice in nursing homes in Ireland to determ...
Nursing home residents; occupational deprivation; occupational engagement; older adults; well-being
0.827
53
Occupational Therapy; Public Health, Environmental and Occupational Health
Health Professions; Medicine
2,024
37,917,881
Ocular Whipple Disease: Cases Diagnosed Over Four Decades.
Ocular immunology and inflammation
Ocul Immunol Inflamm
32
8
10.1080/09273948.2023.2271995
eng
2,024
10
null
2,023
11
2
[PURPOSE] To describe ocular involvement in subjects with Whipple's disease (WD). [METHODS] Retrospective review of documented WD cases seen at Mayo Clinic between 1980 and 2021 with ocular involvement. [RESULTS] Of 217 patients with WD, 30 had eye exams and four (two female, median age 58.5 years) had ocular involveme...
Granulomatous uveitis; infectious uveitis; ocular infection; tropheryma whipplei
0.805
72
Ophthalmology; Immunology and Allergy
Medicine
2,024
37,917,636
Circulating levels of miR125a, miR126, and miR146a-5p in patients with obstructive sleep apnea and their relation with markers of endothelial dysfunction.
PloS one
PLoS One
18
11
10.1371/journal.pone.0287594
eng
2,023
null
null
2,023
11
2
[BACKGROUND] obstructive sleep apnea (OSA) is a prevalent sleep disorder that is associated with increased risk factors for cardiovascular diseases (CVDs). Oxidative stress, insulin resistance, inflammation, and endothelial dysfunction are increased in OSA patients and microRNAs (miRs) are regulatory elements that infl...
null
0.839
467
Multidisciplinary
Multidisciplinary
2,023
37,917,592
Association between serum copper-zinc ratio and respiratory tract infection in children and adolescents.
PloS one
PLoS One
18
11
10.1371/journal.pone.0293836
eng
2,023
null
null
2,023
11
2
[BACKGROUND] The aim of this study was to explore the association between serum copper-zinc (Cu-Zn) ratio and the risk of respiratory tract infection in children and adolescents. [METHODS] This cross-sectional study collected the data of 1695 participants who aged 6-17 years with follow-up data on respiratory tract inf...
null
0.839
467
Multidisciplinary
Multidisciplinary
2,023