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38,459,432
Modulation of early gene expression responses to water deprivation stress by the E3 ubiquitin ligase ATL80: implications for retrograde signaling interplay.
BMC plant biology
BMC Plant Biol
24
1
10.1186/s12870-024-04872-5
eng
2,024
3
8
2,024
3
8
[BACKGROUND] Primary response genes play a pivotal role in translating short-lived stress signals into sustained adaptive responses. In this study, we investigated the involvement of ATL80, an E3 ubiquitin ligase, in the dynamics of gene expression following water deprivation stress. We observed that ATL80 is rapidly a...
Cistrome; E3 ubiquitin ligase; Primary response genes; Retrograde signaling; Water deficient stress
1.134
159
Plant Science
Agricultural and Biological Sciences
2,024
38,459,411
How Primary Care Clinicians Process Patient Death: Logistics, Emotions, and Opportunities for Structural Support.
Journal of general internal medicine
J Gen Intern Med
39
12
10.1007/s11606-024-08702-0
eng
2,024
9
null
2,024
3
8
[BACKGROUND] Navigating the logistics and emotional processing of a patient's death is an inevitable part of many physicians' roles. While research has primarily examined how inpatient clinicians cope with patient loss, little work has explored how primary care clinicians (PCCs) handle patient death in the outpatient s...
emotional processing; logistics; patient death; primary care; support
1.992
224
Internal Medicine
Medicine
2,024
38,459,237
Regulation of the Immune Cell Repertoire in Psoriasis Patients Upon Blockade of IL-17A or TNFα.
Dermatology and therapy
Dermatol Ther (Heidelb)
14
3
10.1007/s13555-024-01112-4
eng
2,024
3
null
2,024
3
8
[INTRODUCTION] Targeting of the proinflammatory cytokine interleukin 17A (IL-17A) or tumor necrosis factor alpha (TNFα) with the monoclonal antibodies (mAbs) ixekizumab or adalimumab, respectively, is a successful therapy for chronic plaque psoriasis. The effects of these treatments on immune cell populations in the sk...
Biologics; Dendritic cells; Immunology; Psoriasis; T cells
1.675
52
Dermatology
Medicine
2,024
38,458,890
Identification of Genes with Rare Loss of Function Variants Associated with Aggressive Prostate Cancer and Survival.
European urology oncology
Eur Urol Oncol
7
2
10.1016/j.euo.2024.02.003
eng
2,024
4
null
2,024
3
7
[BACKGROUND] Prostate cancer (PrCa) is a substantial cause of mortality among men globally. Rare germline mutations in BRCA2 have been validated robustly as increasing risk of aggressive forms with a poorer prognosis; however, evidence remains less definitive for other genes. [OBJECTIVE] To detect genes associated with...
Aggressive prostate cancer; DNA repair genes; Germline prognostic markers; Prostate cancer; Prostate cancer survival
3.419
56
Medicine; Oncology; Radiology, Nuclear Medicine and Imaging; Surgery; Urology
Medicine
2,024
38,458,781
Impacts of income inequality and the mediation role of reporting delays on COVID-19 deaths during 2020 and 2021 in Hong Kong: an observational study.
BMJ open
BMJ Open
14
3
10.1136/bmjopen-2023-078838
eng
2,024
3
8
2,024
3
8
[OBJECTIVE] To estimate the impacts of demographic factors and income disparities on the case fatality rate (CFR) of COVID-19 in Hong Kong, taking into account the influence of reporting delays (ie, the duration between symptom onset and case confirmation). [DESIGN] Retrospective observational longitudinal study. [PART...
COVID-19; Epidemiology; Public health
1.016
176
Medicine
Medicine
2,024
38,458,777
Association between sleep quality and blood pressure control among hypertensive patients at a rural tertiary hospital in Southern Nigeria: a cross-sectional study.
BMJ open
BMJ Open
14
3
10.1136/bmjopen-2023-079774
eng
2,024
3
8
2,024
3
8
[OBJECTIVES] Restorative sleep is critical in preventing hypertension and other chronic diseases. Limited research has explored the relationship between sleep quality and hypertension in Africa. This study investigated the association between sleep quality and blood pressure control among hypertensive patients in South...
Blood Pressure; Hypertension; SLEEP MEDICINE
1.016
176
Medicine
Medicine
2,024
38,458,507
Investigating the influence of probiotics in preventing Traveler's diarrhea: Meta-analysis based systematic review.
Travel medicine and infectious disease
Travel Med Infect Dis
59
null
10.1016/j.tmaid.2024.102703
eng
2,024
null
null
2,024
3
7
[INTRODUCTION] Approximately 10-40 million travelers get Traveler's Diarrhea (TD) yearly. A significant decrease in TD incidence has not been achieved by depending solely on antibiotic prophylaxis and educational initiatives. Using prebiotics to prevent TD has also not been examined in previous evaluations of probiotic...
Diarrhea; Epidemiology; Lactobacilli; Prebiotic; Probiotics; Randomized controlled trial; Saccharomyces
0.955
77
Public Health, Environmental and Occupational Health; Infectious Diseases
Medicine
2,024
38,458,410
Overexpressing of the GIPC1 protects against pathological cardiac remodelling.
European journal of pharmacology
Eur J Pharmacol
971
null
10.1016/j.ejphar.2024.176488
eng
2,024
5
15
2,024
3
7
[OBJECTIVE] Pathological cardiac remodelling, including cardiac hypertrophy and fibrosis, is a key pathological process in the development of heart failure. However, effective therapeutic approaches are limited. The β-adrenergic receptors are pivotal signalling molecules in regulating cardiac function. G-alpha interact...
Cardiac remodelling; GIPC1; MAPK pathways; Ubiquitylation
1.197
210
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
38,458,270
The Value of Using Patient-Specific 3D-Printed Anatomical Models in Surgical Planning for Patients With Complex Multifibroid Uteri.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
J Obstet Gynaecol Can
46
6
10.1016/j.jogc.2024.102435
eng
2,024
6
null
2,024
3
6
[OBJECTIVES] To compare surgeon responses regarding their surgical plan before and after receiving a patient-specific three-dimensional (3D)-printed model of a patient's multifibroid uterus created from their magnetic resonance imaging. [METHODS] 3D-printed models were derived from standard-of-care pelvic magnetic reso...
gynecology; magnetic resonance imaging; minimally invasive surgical procedures; patient care planning; printing; three-dimensional; uterine myomectomy
0.575
86
Obstetrics and Gynecology
Medicine
2,024
38,457,983
ARC@DPBNPs suppress LPS-induced acute lung injury via inhibiting macrophage pyroptosis and M1 polarization by ERK pathway in mice.
International immunopharmacology
Int Immunopharmacol
131
null
10.1016/j.intimp.2024.111794
eng
2,024
4
20
2,024
3
7
[AIM OF THE STUDY] Exploring the protective effect of ARC@DPBNP on lipopolysaccharides (LPS)-induced ALI and its underlying mechanism. [MATERIALS AND METHODS] ALI model was established by intransally administrating LPS (4 mg/kg) into C57BL/6 mice. The suppression effects of ALI was first compared between ARC (intragast...
Acute lung injury; Arctiin; ERK pathway; M1 polarization; Macrophage pyroptosis
1.239
155
Pharmacology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,457,938
Infants with neonatal Chronic Lung Disease are associated with delayed auditory conduction in the rostral brainstem after term.
Clinics (Sao Paulo, Brazil)
Clinics (Sao Paulo)
79
null
10.1016/j.clinsp.2024.100341
eng
2,024
null
null
2,024
3
6
[AIMS] Very Low Birthweight (VLBW) infants with neonatal Chronic Lung Disease (CLD) have been found to have functional impairment of the brainstem auditory pathway at term. This study investigated the functional status of the brainstem auditory pathway in VLBW infants with CLD after term for any abnormality. [METHODS] ...
null
0.612
83
Medicine
Medicine
2,024
38,457,899
Fluoride-amorphous calcium phosphate and biomimetic nano-hydroxyapatite for enamel remineralization: An in-vitro study of surface microhardness and composition.
International orthodontics
Int Orthod
22
2
10.1016/j.ortho.2024.100865
eng
2,024
6
null
2,024
3
7
[AIM] Fluoride-Amorphous Calcium Phosphate and Biomimetic Nano-Hydroxyapatite for Enamel Remineralization; An In-Vitro Study of Surface Microhardness and Composition. [MATERIAL AND METHODS] Ninety-six extracted human premolars with sound buccal surface were divided using a randomization computer-generating software int...
Demineralization; Enamel remineralization; Fluoride varnish; Fluorides; Nano-hydroxyapatite; Orthodontic treatment; Topical*; White spot lesions
0.653
24
Orthodontics
Dentistry
2,024
38,457,804
Comparative effectiveness of stereotactic, subdural, or hybrid intracranial EEG monitoring in epilepsy surgery.
Journal of neurosurgery
J Neurosurg
141
2
10.3171/2024.1.JNS232560
eng
2,024
8
1
2,024
3
8
[OBJECTIVE] Surgical intervention can be curative or palliative for drug-resistant focal epilepsy. However, if the seizure onset zone (SOZ) cannot be adequately localized via noninvasive tests, intracranial EEG (iEEG) recordings are often carried out to develop surgical plans in appropriate candidates. Stereotactic EEG...
SEEG; epilepsy; stereotactic EEG; subdural electrodes; subdural grids; surgical outcomes
1.354
244
Neurology; Surgery
Medicine
2,024
38,457,159
Effects of shoulder brace usage on postural stability in stroke survivors: A pilot randomized controlled trial.
NeuroRehabilitation
NeuroRehabilitation
54
3
10.3233/NRE-230250
eng
2,024
null
null
null
null
null
[BACKGROUND] Despite advances in stroke rehabilitation, challenges in upper limb motor recovery and postural stability persist, negatively affecting overall well-being. Arm slings and shoulder braces have been proposed to address these issues, but their efficacy in promoting postural stability remains unclear. [OBJECTI...
Stroke; neurorehabilitation; postural control; shoulder brace
null
null
null
null
null
38,457,129
Perspectives of Black Patients on Racism Within Emergency Care.
JAMA health forum
JAMA Health Forum
5
3
10.1001/jamahealthforum.2024.0046
eng
2,024
3
1
2,024
3
1
[IMPORTANCE] Numerous Black individuals experience racism persistently throughout their lives, with repercussions extending into health care settings. The perspectives of Black individuals regarding emergency department (ED) care, racism, and patient-centered approaches for dismantling structural racism remain less exp...
null
2.653
33
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
38,456,920
Pediatric neurosurgery training during residency in Switzerland and the need for dedicated subspecialization training.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Childs Nerv Syst
40
6
10.1007/s00381-024-06343-6
eng
2,024
6
null
2,024
3
8
[INTRODUCTION] Pediatric Neurosurgery as a subspeciality started to emerge during the late 1950s, with only a few dedicated pediatric neurosurgeons in the Western world. Over the last few decades, the awareness that children require subspecialized care by dedicated pediatric neurosurgeons and an interdisciplinary team ...
Neurosurgery residency; Pediatric neurosurgery; Pediatric neurosurgery training; Subspeciality training
0.478
100
Pediatrics, Perinatology and Child Health; Medicine; Neurology
Medicine
2,024
38,456,895
Perioperative Morbidity Associated with Same-day Discharge in Elderly Patients.
International urogynecology journal
Int Urogynecol J
35
4
10.1007/s00192-024-05758-8
eng
2,024
4
null
2,024
3
8
[INTRODUCTION AND HYPOTHESIS] We compared postoperative complications in elderly patients discharged on POD#0 versus POD#1 after prolapse repair. [METHODS] Data were obtained from the National Surgical Quality Improvement database. A total of 20,984 women 65 years and older who underwent prolapse repair between 2014 an...
Discharge; Elderly; Prolapse; Same day
0.778
109
Obstetrics and Gynecology; Urology
Medicine
2,024
38,456,499
Molluscicidal effect mechanism study on metaldehyde to Pomacea canaliculate at low temperature.
Pest management science
Pest Manag Sci
80
7
10.1002/ps.8069
eng
2,024
7
null
2,024
3
21
[BACKGROUND] Metaldehyde is a molluscicide commonly used to control Pomacea canaliculate. Its efficacy is significantly impacted by water temperature, although the underlying mechanisms have not been fully explored. [RESULTS] In this study, we systematically investigated the temperature effect and molecular mechanisms ...
Pomacea canaliculata; RNA interference; low temperature; metaldehyde; sensitivity
null
null
null
null
null
38,456,464
Bactericidal Effect of Triple Antibiotic Paste against Enterococcus faecalis in Dentinal Tubules: An Ex Vivo Study.
European endodontic journal
Eur Endod J
9
2
10.14744/eej.2023.78942
eng
2,024
3
null
null
null
null
[OBJECTIVE] The aim of this study was to investigate the bactericidal effect of various concentrations of triple antibiotic paste (TAP) against Enterococcus faecalis (E. faecalis) in dentinal tubules using a bacterial culture assay and confocal laser scanning microscope (CLSM). [METHODS] Ninety human teeth were contami...
null
null
null
null
null
null
38,456,228
Long non-coding RNA lung cancer-associated transcript-1 promotes glioblastoma progression by enhancing Hypoxia-inducible factor 1 alpha activity.
Neuro-oncology
Neuro Oncol
26
8
10.1093/neuonc/noae036
eng
2,024
8
5
null
null
null
[BACKGROUND] Hypoxia is associated with poor prognosis in many cancers including glioblastoma (GBM). Glioma stem-like cells (GSCs) often reside in hypoxic regions and serve as reservoirs for disease progression. Long non-coding RNAs (lncRNAs) have been implicated in GBM. However, the lncRNAs that modulate GSC adaptatio...
LUCAT1; glioma stem-like cells; hypoxia; lncRNA
6.974
178
Cancer Research; Neurology; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,456,154
Promoting the process of determining brain death through standardized training.
Frontiers in neurology
Front Neurol
15
null
10.3389/fneur.2024.1294601
eng
2,024
null
null
2,024
2
22
[OBJECTIVE] This study aims to explore the training mode for brain death determination to ensure the quality of subsequent brain death determination. [METHODS] A four-skill and four-step (FFT) training model was adopted, which included a clinical neurological examination, an electroencephalogram (EEG) examination, a sh...
brain death determination; clinical investigation; practical; practical guidance; standard; training mode; training model
0.993
118
Neurology; Neurology
Medicine; Neuroscience
2,024
38,456,112
Does the Difference in Axial Length Affect the Refractive Outcome?
The Malaysian journal of medical sciences : MJMS
Malays J Med Sci
31
1
10.21315/mjms2024.31.1.6
eng
2,024
2
null
2,024
2
28
[BACKGROUND] The purpose of this study is to compare axial length (AL) and the refractive outcome after phacoemulsification surgery from 2014 to 2019 at Hospital Sultanah Nur Zahirah, Terengganu, Malaysia. [METHOD] This was a retrospective record review of all cataract patients who met the inclusion criteria and underw...
SRK2; axial length; cataract surgery; refractive outcomes; spherical equivalent
0.409
42
Medicine
Medicine
2,024
38,456,029
Monkeypox virus infections in low-risk groups during the 2022-23 global outbreak: An analysis of the WHO global report.
Le infezioni in medicina
Infez Med
32
1
10.53854/liim-3201-2
eng
2,024
null
null
2,024
3
1
[INTRODUCTION] In the 2022-23 Mpox outbreak, cases also occurred in children, adolescents, and adults aged 50 years and older, for whom the risk of transmission is low and whose epidemiological characteristics are less known, compared to high-risk groups such as young adults. Here we describe the epidemiological charac...
Monkeypox; adults; children; epidemiology; older adults; outbreak
null
null
null
null
null
38,455,253
Demographics aspects of brain and spine metastatic melanoma. Retrospective analysis in a single third-level center.
World neurosurgery: X
World Neurosurg X
22
null
10.1016/j.wnsx.2024.100306
eng
2,024
4
null
2,024
2
25
[BACKGROUND] Melanoma metastases to the CNS rank third in frequency, just after lung and breast metastases. There is controversy regarding the factors predisposing to developing CNS metastases in patients with cutaneous melanoma and their survival with conventional treatments. [METHODS] We carried out a retrospective a...
Brain melanoma metastasis; Central nervous system; Melanoma metastatic; Spine melanoma metastasis
0.617
16
Surgery; Neurology
Medicine
2,024
38,454,836
Functional alignment maximises advantages of robotic arm-assisted total knee arthroplasty with better patient-reported outcomes compared to mechanical alignment.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Knee Surg Sports Traumatol Arthrosc
32
4
10.1002/ksa.12120
eng
2,024
4
null
2,024
3
7
[PURPOSE] Robotic arm-assisted total knee arthroplasty (RTKA) enables adjustment of implant position to achieve the surgeon's preferred alignment. However, the alignment concept that most effectively enhances patient satisfaction remains unclear. This study compares the clinical outcomes of patients who underwent funct...
functional alignment; functional knee phenotype; mechanical alignment
1.95
160
Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,024
38,454,824
Clinical outcome and safety of holmium laser prostate enucleation after transrectal prostate biopsies for benign prostatic hyperplasia.
Investigative and clinical urology
Investig Clin Urol
65
2
10.4111/icu.20230276
eng
2,024
3
null
null
null
null
[PURPOSE] This study aimed to assess the clinical outcome and safety of holmium laser enucleation of the prostate (HoLEP) following transrectal ultrasound-guided prostate biopsy (TR biopsy) in the treatment of benign prostate hyperplasia. [MATERIALS AND METHODS] We retrospectively analyzed data from 556 patients who un...
Benign prostatic hyperplasia; Holmium laser; Image-guided biopsy; Lower urinary tract symptoms; Minimally invasive surgical procedure
0.783
30
Urology
Medicine
2,024
38,454,512
The astounding exhaustiveness and speed of the Astral mass analyzer for highly complex samples is a quantum leap in the functional analysis of microbiomes.
Microbiome
Microbiome
12
1
10.1186/s40168-024-01766-4
eng
2,024
3
7
2,024
3
7
[BACKGROUND] By analyzing the proteins which are the workhorses of biological systems, metaproteomics allows us to list the taxa present in any microbiota, monitor their relative biomass, and characterize the functioning of complex biological systems. [RESULTS] Here, we present a new strategy for rapidly determining th...
Functional analysis; Microbiome; Proteotyping; Tandem mass spectrometry; Taxonomy
4.117
163
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
38,454,497
Metabolic signatures and potential biomarkers of sarcopenia in suburb-dwelling older Chinese: based on untargeted GC-MS and LC-MS.
Skeletal muscle
Skelet Muscle
14
1
10.1186/s13395-024-00337-3
eng
2,024
3
7
2,024
3
7
[BACKGROUND] Untargeted metabolomics can be used to expand our understanding of the pathogenesis of sarcopenia. However, the metabolic signatures of sarcopenia patients have not been thoroughly investigated. Herein, we explored metabolites associated with sarcopenia by untargeted gas chromatography (GC)/liquid chromato...
Biomarkers; Metabolomics; Sarcopenia
1.914
60
Cell Biology; Molecular Biology; Orthopedics and Sports Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,454,451
Camrelizumab plus gemcitabine and oxaliplatin for relapsed or refractory classical Hodgkin lymphoma: a phase II trial.
BMC medicine
BMC Med
22
1
10.1186/s12916-024-03329-8
eng
2,024
3
7
2,024
3
7
[BACKGROUND] Classical Hodgkin lymphoma (cHL) is a highly curable disease, while novel therapy is needed for refractory or relapsed (R/R) patients. This phase II trial aimed to evaluate the role of camrelizumab plus gemcitabine and oxaliplatin (GEMOX) in R/R cHL patients. [METHODS] Transplant-eligible patients with R/R...
Camrelizumab; Gemcitabine; Hodgkin disease; Oxaliplatin
2.846
199
Medicine
Medicine
2,024
38,454,427
The influence of prosthetic suspension on gait and cortical modulations is persons with a transfemoral amputation: socket-suspended versus bone-anchored prosthesis.
Journal of neuroengineering and rehabilitation
J Neuroeng Rehabil
21
1
10.1186/s12984-024-01331-y
eng
2,024
3
7
2,024
3
7
[BACKGROUND] Persons with a transfemoral amputation (TFA) often experience difficulties in daily-life ambulation, including an asymmetrical and less stable gait pattern and a greater cognitive demand of walking. However, it remains unclear whether this is effected by the prosthetic suspension, as eliminating the non-ri...
Amputee; Cortical; EEG; Gait; Osseointegration; Prosthesis; Socket; Stability
1.287
129
Health Informatics; Rehabilitation
Medicine
2,024
38,454,324
Applying Sydney Triage to Admission Risk Tool (START) to improve patient flow in emergency departments: a multicentre randomised, implementation study.
BMC emergency medicine
BMC Emerg Med
24
1
10.1186/s12873-024-00956-5
eng
2,024
3
7
2,024
3
7
[BACKGROUND] To determine the effectiveness of applying the Sydney Triage to Admission Risk Tool (START) in conjunction with senior early assessment in different Emergency Departments (EDs). [METHODS] This multicentre implementation study, conducted in two metropolitan EDs, used a convenience sample of ED patients. Pat...
Decision support; Emergency; Patient flow; Triage
0.841
51
Emergency Medicine
Medicine
2,024
38,454,067
Maximal detrusor pressure can be predicted using technetium-99m-mertcaptoacetyltriglycine renal scintigraphy in the early stages of spinal cord injury.
Spinal cord
Spinal Cord
62
5
10.1038/s41393-024-00967-w
eng
2,024
5
null
2,024
3
7
[STUDY DESIGN] Retrospective cohort study. [OBJECTIVE] To investigate the potential of technetium-99m-mercaptoacetyltriglycine (99mTc-MAG-3) renal scintigraphy for predicting maximal detrusor pressure in the early stages of spinal cord injury (SCI). [SETTING] Tertiary rehabilitation facility. [METHODS] Medical records ...
null
0.945
131
Medicine; Rehabilitation; Neurology; Neurology
Medicine; Neuroscience
2,024
38,454,065
Knowledge, perceptions, and beliefs about urinary tract infections in persons with neurogenic bladder and impacts on interventions to promote person-centered care.
Spinal cord
Spinal Cord
62
5
10.1038/s41393-024-00972-z
eng
2,024
5
null
2,024
3
7
[STUDY DESIGN] Qualitative study. [OBJECTIVES] To explore how knowledge, perceptions, and beliefs about urinary tract infections (UTIs) among persons with neurogenic bladder (NB) may impact health behaviors and provider management and enhance person-centeredness of interventions to improve UTI management. [SETTING] Thr...
null
0.945
131
Medicine; Rehabilitation; Neurology; Neurology
Medicine; Neuroscience
2,024
38,453,768
Early Contrast-Enhanced MR for Diagnosing Complete Tumor Response of Locally Advanced Esophageal Squamous Cell Carcinoma After Neoadjuvant Therapy: A Retrospective Comparative Study.
Annals of surgical oncology
Ann Surg Oncol
31
7
10.1245/s10434-024-15123-0
eng
2,024
7
null
2,024
3
7
[BACKGROUND] This study assessed the performance of early contrast-enhanced magnetic resonance (ECE-MR) in the detecting of complete tumor response (ypT0) in patients with esophageal squamous cell carcinoma following neoadjuvant therapy. [PATIENTS AND METHODS] Preoperative MR images of consecutive patients who underwen...
Esophageal squamous cell carcinoma; Magnetic resonance imaging; Neoadjuvant therapy
1.152
210
Surgery; Oncology
Medicine
2,024
38,453,357
Predictability of the National Psychological Stress Screening for Subsequent Long-Term Psychiatric Sick Leave Among Employees: A Multicenter Nested Case-Control Study.
Journal of occupational and environmental medicine
J Occup Environ Med
66
5
10.1097/JOM.0000000000003078
eng
2,024
5
1
2,024
3
7
[OBJECTIVE] The aim of the study is to predict employees' long-term sick leave due to psychiatric disorders using the national psychological stress screening program. [METHODS] University employees who took long-term psychiatric sick leave in 2016-2018 were assigned as cases. Those who were present at work and matched ...
null
0.743
130
Public Health, Environmental and Occupational Health
Medicine
2,024
38,506,329
A concept of "cultural competence" among public health nurses in Japan.
Public health nursing (Boston, Mass.)
Public Health Nurs
41
3
10.1111/phn.13307
eng
2,024
null
null
2,024
3
20
[OBJECTIVES] To clarify the conceptual structure of "cultural competence (CC)" among Japanese public health nurses (PHNs), to enhance culturally appropriate support. [METHODS] A modified grounded theory approach (M-GTA) was used. A total of 11 municipal PHNs participated in this study. Data were collected through semis...
Japan; conceptual models; cultural competence; cultural humility; public health nurse; qualitative research; transcultural nursing
0.723
63
Nursing; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,024
38,504,839
Relevance of Tumor Budding and Pattern of Invasion in Oral Squamous Cell Carcinoma.
International journal of applied & basic medical research
Int J Appl Basic Med Res
14
1
10.4103/ijabmr.ijabmr_391_23
eng
2,024
null
null
2,024
2
20
[BACKGROUND] Standard histopathological parameters such as depth of invasion (DOI), lymphovascular invasion (LVI), and perineural invasion (PNI) are known parameters that can correlate with the prognosis and aggressiveness of oral squamous cell carcinomas (OSCCs). Tumor budding (TB) (≤5 tumor cells at infiltrating bord...
Oral squamous cell carcinoma; pattern of invasion; tumor budding
null
null
null
null
null
38,504,805
Development of entrustable professional activities for emergency medicine medical education fellowships: A modified Delphi study.
AEM education and training
AEM Educ Train
8
1
10.1002/aet2.10944
eng
2,024
2
null
2,024
2
21
[BACKGROUND] It is essential that medical education (MedEd) fellows achieve desired outcomes prior to graduation. Despite the increase in postgraduate MedEd fellowships in emergency medicine (EM), there is no consistently applied competency framework. We sought to develop entrustable professional activities (EPAs) for ...
null
0.631
26
Education; Emergency Medicine; Emergency Nursing
Medicine; Nursing; Social Sciences
2,024
38,504,691
Post-COVID-19 physical and cognitive impairments and associations with quality of life: a cross-sectional study.
Frontiers in sports and active living
Front Sports Act Living
6
null
10.3389/fspor.2024.1246585
eng
2,024
null
null
2,024
3
5
[BACKGROUND AND OBJECTIVE] This study aimed to compare physical and cognitive functions between post-coronavirus disease 2019 (COVID-19) participants and healthy matched controls and investigate associations between physical and cognitive impairments with quality of life. [METHODS] Twenty-three post-COVID-19 participan...
COVID-19; cognitive impairment; long COVID; physical impairment; quality of life
0.864
28
Anthropology; Physical Therapy, Sports Therapy and Rehabilitation; Orthopedics and Sports Medicine; Physiology; Public Health, Environmental and Occupational Health; Tourism, Leisure and Hospitality Management
Biochemistry, Genetics and Molecular Biology; Business, Management and Accounting; Health Professions; Medicine; Social Sciences
2,024
38,504,646
New-Onset Vision Impairment in Children: Magnetic Resonance Imaging Findings by Age Groups.
Journal of child neurology
J Child Neurol
39
3-4
10.1177/08830738241239696
eng
2,024
3
null
2,024
3
20
[INTRODUCTION] Non-traumatic visual impairment is rare in the pediatric population, but early diagnosis and treatment of the cause is crucial to prevent long-term consequences affecting children's neurocognitive development. The authors aim to determine the most common causes of non-traumatic visual impairment in pedia...
demyelinating disorders; idiopathic intracranial hypertension; magnetic resonance imaging; pediatric patients; vision impairment
0.586
123
Pediatrics, Perinatology and Child Health; Neurology
Medicine
2,024
38,504,360
Efficacy and safety of canakinumab in systemic juvenile idiopathic arthritis, the first Chinese experience.
Pediatric rheumatology online journal
Pediatr Rheumatol Online J
22
1
10.1186/s12969-024-00974-4
eng
2,024
3
19
2,024
3
19
[BACKGROUND] Systemic juvenile idiopathic arthritis (sJIA) is a severe form of juvenile arthritis that is characterized by chronic joint inflammation and systemic symptoms such as fever, rash, and organ involvement. Anti-IL-6 receptor monoclonal antibody tocilizumab is an effective treatment. However, some patients sti...
Canakinumab; Interleukin-1; Systemic juvenile idiopathic arthritis
null
null
null
null
null
38,503,580
Effects of different dietary fiber supplement strategies on incidence of acute gastrointestinal injury in ICU patients: A prospective observational study.
Intensive & critical care nursing
Intensive Crit Care Nurs
84
null
10.1016/j.iccn.2024.103673
eng
2,024
10
null
2,024
3
19
[OBJECTIVE] This study aimed to explore the effects of dietary fiber (DF) supplement strategies on the incidence of acute gastrointestinal injury (AGI) in critically ill patients. [DESIGN] A prospective observational study. [SETTING] The study was conducted in the First Affiliated Hospital of Soochow University from Ap...
Acute gastrointestinal injury; Critically ill patients; Dietary fiber
null
null
null
null
null
38,503,484
Circuit-based neuromodulation enhances delayed recall in amnestic mild cognitive impairment.
Journal of neurology, neurosurgery, and psychiatry
J Neurol Neurosurg Psychiatry
95
10
10.1136/jnnp-2023-333152
eng
2,024
9
17
2,024
9
17
[BACKGROUND] This study aimed to investigate the efficacy of circuits-based paired associative stimulation (PAS) in adults with amnestic mild cognitive impairment (aMCI). [METHODS] We conducted a parallel-group, randomised, controlled clinical trial. Initially, a cohort of healthy subjects was recruited to establish th...
CLINICAL NEUROLOGY; COGNITION
3.379
244
Neurology; Psychiatry and Mental Health; Surgery
Medicine
2,024
38,503,155
Multitarget anti-parasitic activities of isoquinoline alkaloids isolated from Hippeastrum aulicum (Amaryllidaceae).
Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine
128
null
10.1016/j.phymed.2024.155414
eng
2,024
6
null
2,024
2
5
[BACKGROUND] Chagas disease and leishmaniasis affect a significant portion of the Latin American population and still lack efficient treatments. In this context, natural products emerge as promising compounds for developing more effective therapies, aiming to mitigate side effects and drug resistance. Notably, species ...
Alkaloids; Amaryllidaceae; Chagas disease; Hippeastrum aulicum; Leishmania; Multitarget; Trypanosoma cruzi
1.694
150
Complementary and Alternative Medicine; Drug Discovery; Molecular Medicine; Pharmaceutical Science; Pharmacology
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,503,008
Determining steady-state trough range in vancomycin drug dosing using machine learning.
Journal of critical care
J Crit Care
82
null
10.1016/j.jcrc.2024.154784
eng
2,024
8
null
2,024
3
18
[BACKGROUND] Vancomycin is a renally eliminated, nephrotoxic, glycopeptide antibiotic with a narrow therapeutic window, widely used in intensive care units (ICU). We aimed to predict the risk of inappropriate vancomycin trough levels and appropriate dosing for each ICU patient. [METHODS] Observed vancomycin trough leve...
Artificial intelligence; Intensive care unit; Vancomycin dosing
1.021
109
Critical Care and Intensive Care Medicine
Medicine
2,024
38,502,720
Impact of Incomplete Revascularization After PCI in Left Main Disease: The EXCEL Trial.
Circulation. Cardiovascular interventions
Circ Cardiovasc Interv
17
3
10.1161/CIRCINTERVENTIONS.123.013192
eng
2,024
3
null
2,024
3
19
[BACKGROUND] The importance of complete revascularization after percutaneous coronary intervention (PCI) in patients with left main coronary artery disease is uncertain. We investigated the clinical impact of complete revascularization in patients with left main coronary artery disease undergoing PCI in the EXCEL trial...
Duke Jeopardy Score; SYNTAX score; complete revascularization; outcomes; percutaneous coronary intervention
null
null
null
null
null
38,502,665
Interpretable machine learning-based individual analysis of acute kidney injury in immune checkpoint inhibitor therapy.
PloS one
PLoS One
19
3
10.1371/journal.pone.0298673
eng
2,024
null
null
2,024
3
19
[BACKGROUND] Acute kidney injury (AKI) is a critical complication of immune checkpoint inhibitor therapy. Since the etiology of AKI in patients undergoing cancer therapy varies, clarifying underlying causes in individual cases is critical for optimal cancer treatment. Although it is essential to individually analyze im...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
38,502,607
Work With ChatGPT, Not Against: 3 Teaching Strategies That Harness the Power of Artificial Intelligence.
Nurse educator
Nurse Educ
49
3
10.1097/NNE.0000000000001634
eng
null
null
null
2,024
3
18
[BACKGROUND] Technological advances have expanded nursing education to include generative artificial intelligence (AI) tools such as ChatGPT. [PROBLEM] Generative AI tools challenge academic integrity, pose a challenge to validating information accuracy, and require strategies to ensure the credibility of AI-generated ...
null
null
null
null
null
null
38,502,313
Synchronous versus metachronous spinal metastasis: a comparative study of survival outcomes following neurosurgical treatment.
Journal of cancer research and clinical oncology
J Cancer Res Clin Oncol
150
3
10.1007/s00432-024-05657-x
eng
2,024
3
19
2,024
3
19
[PURPOSE] Patients with spinal metastases (SM) from solid neoplasms typically exhibit progression to an advanced cancer stage. Such metastases can either develop concurrently with an existing cancer diagnosis (termed metachronous SM) or emerge as the initial indication of an undiagnosed malignancy (referred to as synch...
Neuro-oncology; Surgery for spinal metastasis; Survival; Synchronous versus metachronous tumor occurrence
0.91
114
Medicine; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,501,739
The BMP7-Derived Peptide p[63-82] Reduces Cartilage Degeneration in the Rat ACLT-pMMx Model for Posttraumatic Osteoarthritis.
Cartilage
Cartilage
null
null
10.1177/19476035241233659
eng
2,024
3
19
2,024
3
19
[OBJECTIVE] Osteoarthritis (OA) is characterized by articular cartilage erosion, pathological subchondral bone changes, and signs of synovial inflammation and pain. We previously identified p[63-82], a bone morphogenetic protein 7 (BMP7)-derived bioactive peptide that attenuates structural cartilage degeneration in the...
articular cartilage; cartilage degeneration; osteoarthritis; pain; peptides; subchondral bone
1.064
52
Biomedical Engineering; Physical Therapy, Sports Therapy and Rehabilitation; Immunology and Allergy
Engineering; Health Professions; Medicine
2,024
38,501,534
COVID-19 in patients with Down syndrome: A systematic review.
Immunity, inflammation and disease
Immun Inflamm Dis
12
3
10.1002/iid3.1219
eng
2,024
3
null
null
null
null
[INTRODUCTION] Down syndrome (DS) is associated with multiple comorbid conditions and chronic immune dysfunction. Persons with DS who contract COVID-19 are at high risk for complications and have a poor prognosis. We aimed to study the clinical symptoms, laboratory and biochemical profiles, radiologic findings, treatme...
COVID-19; Down syndrome; clinical outcomes; clinical symptoms; mortality
0.814
38
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
38,501,508
Toward Telemonitoring in Immune-Mediated Inflammatory Diseases: Protocol for a Mixed Attention Model Study.
JMIR research protocols
JMIR Res Protoc
13
null
10.2196/55829
eng
2,024
4
22
2,024
4
22
[BACKGROUND] Rheumatic and musculoskeletal diseases (RMDs) are chronic diseases that may alternate between asymptomatic periods and flares. These conditions require complex treatments and close monitoring by rheumatologists to mitigate their effects and improve the patient's quality of life. Often, delays in outpatient...
MAM; antirheumatic drugs; care model; chronic diseases; clinical outcome; digital health; digital resources, mixed attention model; hybrid care model; implementation; inflammation; musculoskeletal diseases; pain; rheumatic disease; rheumatology; telemonitoring
0.527
45
Medicine
Medicine
2,024
38,501,456
Arthroscopic Implantation of a Cell-Free Bilayer Scaffold for the Treatment of Knee Chondral Lesions: A 2-Year Prospective Study.
Cartilage
Cartilage
16
1
10.1177/19476035241232061
eng
2,025
3
null
2,024
3
19
[OBJECTIVE] The main objective of this study is to assess the safety and clinical efficacy of a cell-free bilayer scaffold (MaioRegen Chondro+ by Fin-Ceramica) in patients affected by chondral knee lesions of different origin and localization. [DESIGN] Thirty-one patients with focal chondral lesions of the knee were ar...
articular cartilage; cartilage regeneration; cartilage repair; cell-free bilayer scaffold; knee
1.064
52
Biomedical Engineering; Physical Therapy, Sports Therapy and Rehabilitation; Immunology and Allergy
Engineering; Health Professions; Medicine
2,024
38,501,455
A Traumatic Impact Immediately Changes the Mechanical Properties of Articular Cartilage.
Cartilage
Cartilage
null
null
10.1177/19476035241235633
eng
2,024
3
19
2,024
3
19
[OBJECTIVE] To investigate whether and how a single traumatic impact changes the mechanical properties of talar articular cartilage. [DESIGN] A marble was placed on the joint surface and a weight was dropped on both medial and lateral caprine talus to create a well-defined single focal impact. The mechanical properties...
ankle; cartilage; impact; micro-indentation; osteoarthritis
1.064
52
Biomedical Engineering; Physical Therapy, Sports Therapy and Rehabilitation; Immunology and Allergy
Engineering; Health Professions; Medicine
2,024
38,500,646
Benefit finding in individuals undergoing maintenance hemodialysis in Shanghai: a latent profile analysis.
Frontiers in psychology
Front Psychol
15
null
10.3389/fpsyg.2024.1292175
eng
2,024
null
null
2,024
3
4
[OBJECTIVE] This multi-center cross-sectional study aimed to delineate latent profiles of benefit finding (BF) in individuals undergoing maintenance hemodialysis (MHD) in Shanghai and examine associations between these BF profiles, social support, and coping style. [METHODS] A total of 384 individuals undergoing MHD (m...
benefit finding; coping style; latent profile analysis; maintenance hemodialysis; social support
0.872
212
Psychology
Psychology
2,024
38,500,554
Contingency Reversal in Conditioned Fear Learning: The Moderated Mediation Model of Intolerance of Uncertainty and Instruction.
Psychology research and behavior management
Psychol Res Behav Manag
17
null
10.2147/PRBM.S447426
eng
2,024
null
null
2,024
3
12
[OBJECTIVE] The study aimed to examine the roles of anxiety and intolerance of uncertainty (IU) in conditioned fear learning under an uncertain context induced by the contingency reversal of the association between the conditioned stimulus and the unconditioned stimulus (CS-US). [METHODS] The study sample comprised 53 ...
associations learning; fear generalization; instructional learning; moderated mediation model
0.92
56
Psychiatry and Mental Health; Psychology
Medicine; Psychology
2,024
38,500,553
Correlations between Steady-State Pattern Electroretinogram and Humphrey Visual Field Analyzer Global Indices and Their Associations with Retinal Ganglion Cell Layer-Inner Plexiform Layer Thickness in Glaucoma Suspects.
Journal of ophthalmology
J Ophthalmol
2024
null
10.1155/2024/2443887
eng
2,024
null
null
2,024
3
11
[PURPOSE] The purpose of this study was to investigate the utility of steady state pattern electroretinogram (ss-PERG) in detecting retinal ganglion cell (RGC) dysfunction in glaucoma suspects (GS) who had normal 24-2 Humphrey Visual Fields (HFA). [MATERIALS AND METHODS] This was a prospective cohort study of GS patien...
null
0.815
65
Ophthalmology
Medicine
2,024
38,500,233
A descriptive study of stroke types, risk factors, clinical features, and outcomes in a tertiary hospital in Myanmar.
Tropical medicine and health
Trop Med Health
52
1
10.1186/s41182-024-00592-6
eng
2,024
3
18
2,024
3
18
[BACKGROUND] Stroke is a leading cause of death in the world, and the burden of stroke is higher in low- and middle-income countries. Understanding the risk factors, complications, and outcomes of stroke are useful for healthcare planning and resource allocation. Little information on stroke is available for many low- ...
Hypertension; Myanmar; Risk factors of stroke; Stroke
0.844
41
Infectious Diseases; Public Health, Environmental and Occupational Health
Medicine
2,024
38,500,220
Childhood obesity and risk of Alzheimer's disease: a Mendelian randomization study.
Archives of public health = Archives belges de sante publique
Arch Public Health
82
1
10.1186/s13690-024-01271-y
eng
2,024
3
18
2,024
3
18
[BACKGROUND] Midlife obesity is a modifiable risk factor for Alzheimer's disease. However, the association between childhood obesity and Alzheimer's disease remains largely unknown. Therefore, we conducted a mendelian randomization analysis (MR) to assess the causal link between childhood obesity and Alzheimer's diseas...
Alzheimer's disease; Childhood obesity; Dementia; Mendelian randomization
null
null
null
null
null
38,500,146
Updated single cell reference atlas for the starlet anemone Nematostella vectensis.
Frontiers in zoology
Front Zool
21
1
10.1186/s12983-024-00529-z
eng
2,024
3
18
2,024
3
18
[BACKGROUND] The recent combination of genomics and single cell transcriptomics has allowed to assess a variety of non-conventional model organisms in much more depth. Single cell transcriptomes can uncover hidden cellular complexity and cell lineage relationships within organisms. The recent developmental cell atlases...
Cnidarian development; Neuronal inventory; Transcriptomics; scRNAseq
null
null
null
null
null
38,500,075
Medical students' perceptions of integrating social media into a narrative medicine programme for 5th-year clerkship in Taiwan: a descriptive qualitative study.
BMC medical education
BMC Med Educ
24
1
10.1186/s12909-024-05255-y
eng
2,024
3
18
2,024
3
18
[BACKGROUND] The growing demands in integrating digital pedagogies in learning (e.g., social media) contribute to disrupting many fields, including the medical humanities education. However, the strengths and barriers behind social media and medical humanities context are blurred and contradictive. We examined the perc...
Descriptive qualitative study; Medical students; Narrative medicine; Perception; Social media
0.947
107
Education; Medicine
Medicine; Social Sciences
2,024
38,500,019
Health-related social needs information in the emergency department: clinician and patient perspectives on availability and use.
BMC emergency medicine
BMC Emerg Med
24
1
10.1186/s12873-024-00959-2
eng
2,024
3
18
2,024
3
18
[BACKGROUND] Patient health-related social needs (HRSN) complicate care and drive poor outcomes in emergency department (ED) settings. This study sought to understand what HRSN information is available to ED physicians and staff, and how HRSN-related clinical actions may or may not align with patient expectations. [MET...
Clinician; Emergency department; Health-related social needs; Patient; Staff
0.841
51
Emergency Medicine
Medicine
2,024
38,499,963
The association between neighborhood social and built environment on loneliness among young adults with cancer.
Journal of cancer survivorship : research and practice
J Cancer Surviv
null
null
10.1007/s11764-024-01563-w
eng
2,024
3
18
2,024
3
18
[PURPOSE] Young adults with cancer (YAs, aged 18-39) are at increased risk of experiencing loneliness due to their unique challenges of coping with a cancer diagnosis and treatment during young adulthood. Understanding factors that impact loneliness is critical to improving survivorship outcomes for this vulnerable YA ...
Built environment; Loneliness; Social cohesion; Young adults
1.402
87
Oncology; Oncology
Medicine; Nursing
2,024
38,499,357
Low-dose ketamine infusion to facilitate opioid tapering in chronic non-cancer pain with opioid-use disorder: a historical cohort study.
Regional anesthesia and pain medicine
Reg Anesth Pain Med
50
5
10.1136/rapm-2023-105035
eng
2,025
5
6
2,025
5
6
[BACKGROUND] Long-term opioid use is associated with pharmacological tolerance, a risk of misuse and hyperalgesia in patients with chronic pain (CP). Tapering is challenging in this context, particularly with comorbid opioid-use disorder (OUD). The antihyperalgesic effect of ketamine, through N-methyl-D-aspartate (NMDA...
Analgesics, Opioid; CHRONIC PAIN; Opioid-Related Disorders
1.411
130
Anesthesiology and Pain Medicine; Medicine
Medicine
2,024
38,499,270
Cardiovascular magnetic resonance reference values of right ventricular volumetric variables in patients with hypoplastic left heart syndrome.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
J Cardiovasc Magn Reson
26
1
10.1016/j.jocmr.2024.101038
eng
2,024
null
null
2,024
3
16
[BACKGROUND] Cardiovascular magnetic resonance (CMR) has established itself as the gold standard for serial assessment of systemic right ventricular (RV) performance but due to the lack of standardized RV reference values for hypoplastic left heart syndrome (HLHS) patients, the interpretation of RV volumetric data in H...
Cardiovascular magnetic resonance; Children; Hypoplastic left heart syndrome; Reference values
1.728
119
Cardiology and Cardiovascular Medicine; Family Practice; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,024
38,498,975
Long-Term Outcomes of dMMR/MSI-H Rectal Cancer Treated With Anti-PD-1-Based Immunotherapy as Curative-Intent Treatment.
Journal of the National Comprehensive Cancer Network : JNCCN
J Natl Compr Canc Netw
22
3
10.6004/jnccn.2023.7096
eng
2,024
3
18
2,024
3
18
[BACKGROUND] Neoadjuvant anti-PD-1 therapy has shown encouraging efficacy in patients with deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) locally advanced rectal cancer (LARC), which suggests its potential as a curative-intent therapy and a promising treatment option for organ preservation...
null
null
null
null
null
null
38,498,497
Priority-setting for hospital funding of high-cost innovative drugs and therapeutics: A qualitative institutional case study.
PloS one
PLoS One
19
3
10.1371/journal.pone.0300519
eng
2,024
null
null
2,024
3
18
[OBJECTIVES] Rising costs of innovative drugs and therapeutics (DTs) have led to resource allocation challenges for healthcare institutions. There is limited evidence to guide priority-setting for institutional funding of high-cost DTs. This study sought to identify and elaborate on the substantive principles and proce...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
38,498,296
The role of endothelial growth factor and tear levels in diabetic retinopathy in type 2 diabetes.
International ophthalmology
Int Ophthalmol
44
1
10.1007/s10792-024-03064-2
eng
2,024
3
18
2,024
3
18
[PURPOSE] To evaluate the tear level of VEGF and the quantity of tear film in type 2 diabetic patients. [METHODS] Thirty patients with diabetic retinopathy (DR group) and 30 patients with no DR (NDR group), and 30 healthy subjects with age and gender matching were enrolled in this prospective comparative study. The tea...
Diabetes mellitus type 2; Diabetic retinopathy; Endothelial growth factor; Tear volume
0.642
57
Ophthalmology
Medicine
2,024
38,498,223
Artificial intelligence for caries detection: a novel diagnostic tool using deep learning algorithms.
Oral radiology
Oral Radiol
40
3
10.1007/s11282-024-00741-x
eng
2,024
7
null
2,024
3
18
[OBJECTIVES] The aim of this study was to develop an assessment tool for automatic detection of dental caries in periapical radiographs using convolutional neural network (CNN) architecture. [METHODS] A novel diagnostic model named ResNet + SAM was established using numerous periapical radiographs (4278 images) annotat...
Artificial intelligence (AI); Deep learning; Dental caries; Dentistry; Periapical radiographs
0.589
28
Dentistry; Radiology, Nuclear Medicine and Imaging
Dentistry; Medicine
2,024
38,498,189
Research progress on incomplete partition type 3 inner ear malformation.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Eur Arch Otorhinolaryngol
281
8
10.1007/s00405-024-08555-7
eng
2,024
8
null
2,024
3
18
[PURPOSE] This review aims to provides a comprehensive overview of the latest research progress on IP-III inner ear malformation, focusing on its geneticbasis, imaging features, cochlear implantation, and outcome. [METHODS] Review the literature on clinical and genetic mechanisms associated with IP-III. [RESULTS] Mutat...
Cochlear implantation; Incomplete partition type III; Inner ear malformation; POU3F4 gene
0.787
94
Otorhinolaryngology; Medicine
Medicine
2,024
38,498,141
Efficacy and Safety of Risankizumab for Active Psoriatic Arthritis: 100-Week Results from the Phase 3 KEEPsAKE 1 Randomized Clinical Trial.
Rheumatology and therapy
Rheumatol Ther
11
3
10.1007/s40744-024-00654-5
eng
2,024
6
null
2,024
3
18
[INTRODUCTION] Patients with psoriatic arthritis (PsA) require treatment providing durable long-term efficacy in different disease domains as well as safety. We present 100-week efficacy and safety results of risankizumab in patients with active PsA and previous inadequate response/intolerance to ≥ 1 conventional synth...
IL-23; Long-term treatment; Psoriatic arthritis; Risankizumab; csDMARD-IR
1.099
40
Immunology and Allergy; Rheumatology
Medicine
2,024
38,497,934
Clinical criteria accurately diagnose severe but not moderate alcohol-associated hepatitis: A systematic review and meta-analysis.
Hepatology communications
Hepatol Commun
8
4
10.1097/HC9.0000000000000404
eng
2,024
4
1
2,024
3
18
[BACKGROUND] The precision of clinical criteria and the utility of liver biopsy for diagnosis or prognosis remain unclear in patients with alcohol-associated hepatitis (AH). We systematically reviewed the literature to answer these questions. [METHODS] Four databases were searched for studies describing the precision o...
null
2.114
60
Hepatology
Medicine
2,024
38,497,860
The comparison of 1-year results for mini and wide-size cap grafts applied to nasal tips.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
28
5
10.26355/eurrev_202403_35591
eng
2,024
3
null
null
null
null
[OBJECTIVE] In the present study, we evaluated patient satisfaction with cap grafts by Rhinoplasty Outcomes Evaluation (ROE) scores. Mini cap and wide cap grafts were applied. [PATIENTS AND METHODS] A total of 80 patients who underwent a rhinoplasty operation with cap graft application to the tip region were included i...
null
null
null
null
null
null
38,497,809
Apomixis and the paradox of sex in plants.
Annals of botany
Ann Bot
134
1
10.1093/aob/mcae044
eng
2,024
6
7
null
null
null
[BACKGROUND] The predominance of sex in eukaryotes, despite the high costs of meiosis and mating, remains an evolutionary enigma. Many theories have been proposed, none of them being conclusive on its own, and they are, in part, not well applicable to land plants. Sexual reproduction is obligate in embryophytes for the...
Apomixis; apogamy; haploid selection; meiosis; polyploidy; stress response; terrestrialization
1.294
215
Plant Science
Agricultural and Biological Sciences
2,024
38,497,579
Aneurysms Located beyond the Origin of the Major Branches in the Posterior Circulation.
Turkish neurosurgery
Turk Neurosurg
34
3
10.5137/1019-5149.JTN.45317-23.1
eng
2,024
null
null
null
null
null
[AIM] To evaluate the clinical and radiological features, treatment modalities, and outcomes of unusual aneurysms located beyond the origin of the major branches in the posterior circulation, and to introduce changes in the recent treatment trends due to rapid innovations in endovascular technology. [MATERIAL AND METHO...
null
0.346
36
Neurology; Surgery
Medicine
2,024
38,497,457
Prognostic Implications of Left Atrial Strain in Bicuspid Aortic Valve With Chronic Aortic Regurgitation.
Journal of the American Heart Association
J Am Heart Assoc
13
6
10.1161/JAHA.123.032770
eng
2,024
3
19
2,024
3
18
[BACKGROUND] Left atrial reservoir strain (LARS) is a novel imaging biomarker of left ventricular diastolic dysfunction. This study aimed to examine the prognostic implications of LARS in patients with bicuspid aortic valve and significant (moderate-severe to severe) aortic regurgitation. [METHODS AND RESULTS] A total ...
aortic regurgitation; bicuspid aortic valve; left atrial strain
2.189
152
Cardiology and Cardiovascular Medicine
Medicine
2,024
38,496,776
Empowering Radiographers: A Call for Integrated AI Training in University Curricula.
International journal of biomedical imaging
Int J Biomed Imaging
2024
null
10.1155/2024/7001343
eng
2,024
null
null
2,024
3
8
[BACKGROUND] Artificial intelligence (AI) applications are rapidly advancing in the field of medical imaging. This study is aimed at investigating the perception and knowledge of radiographers towards artificial intelligence. [METHODS] An online survey employing Google Forms consisting of 20 questions regarding the rad...
null
null
null
null
null
null
38,496,711
Exploring pregnant individuals' counseling needs regarding urgent imaging to rule out pulmonary embolism.
Research and practice in thrombosis and haemostasis
Res Pract Thromb Haemost
8
2
10.1016/j.rpth.2024.102317
eng
2,024
2
null
2,024
1
17
[BACKGROUND] Computed tomography pulmonary angiogram and lung scintigraphy with ventilation/perfusion scan are needed to diagnose pulmonary embolism (PE) in pregnancy. Their associated ionizing radiation doses are considered safe in pregnancy. A standardized patient information tool may improve patient counseling and r...
computed tomography angiography; patient education; pregnancy; pulmonary embolism; radiation; ventilation-perfusion scan
0.93
43
Hematology
Medicine
2,024
38,496,476
Manifold learning uncovers nonlinear interactions between the adolescent brain and environment that predict emotional and behavioral problems.
bioRxiv : the preprint server for biology
bioRxiv
null
null
10.1101/2024.02.29.582854
eng
2,024
6
21
2,024
6
21
[BACKGROUND] To progress adolescent mental health research beyond our present achievements - a complex account of brain and environmental risk factors without understanding neurobiological embedding in the environment - we need methods to unveil relationships between the developing brain and real-world environmental ex...
adolescent; brain function; emotional and behavioral problems; environment; manifold learning; mental health
null
null
null
null
null
38,496,471
Prevalence of Biomarkers and Associated Factors for Chronic Kidney Disease in Adult Diabetic Out-patients in a Tertiary Hospital in Eastern Uganda - a Cross-sectional Study.
Research square
Res Sq
null
null
10.21203/rs.3.rs-3992049/v1
eng
2,024
3
5
2,024
3
5
[BACKGROUND] Chronic kidney disease (CKD) is one of the most common complications of Diabetes Mellitus (DM). DM contributes to about 66% of CKD cases globally. CKiiiD results in increased morbidity and mortality and advanced stages often require renal replacement therapy that is unaffordable for the majority of the pat...
null
null
null
null
null
null
38,496,259
Bone morphogenetic protein 10 and atrial fibrillation.
International journal of cardiology. Heart vasculature
Int J Cardiol Heart Vasc
51
null
10.1016/j.ijcha.2024.101376
eng
2,024
4
null
2,024
3
8
[BACKGROUND] The association between bone morphogenetic protein 10 (BMP10) and atrial fibrillation (AF) has been widely investigated by observational studies, but their causal relationships remain inconclusive. Here, we aimed to evaluate the causal effect of BMP10 on the risk of AF through single-nucleotide polymorphis...
Atrial fibrillation; BMP10; Mendelian randomization
null
null
null
null
null
38,495,318
PharmD students experiences on end year clerkship evaluation using objective structured clinical exam (OSCE) method at JSS College of Pharmacy, Mysuru, India.
PEC innovation
PEC Innov
4
null
10.1016/j.pecinn.2024.100271
eng
2,024
12
null
2,024
3
5
[OBJECTIVES] To assess the PharmD student's experiences about end year clerkship evaluation conducted using Objective Structured Clinical Exam (OSCE) format at JSS College of Pharmacy, Mysuru, India. [METHODS] The student's experiences were captured using a newly developed, 14-item, 5-point Likert's scale feedback form...
Clinical pharmacy; Clinical skills; Objective structured clinical exam; PharmD clerkship
0.585
8
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
38,494,985
Greater need but reduced access: a population study of planned and elective surgery rates in adult mental health service users.
Epidemiology and psychiatric sciences
Epidemiol Psychiatr Sci
33
null
10.1017/S2045796024000131
eng
2,024
3
18
2,024
3
18
[AIMS] Timely access to surgery is an essential part of healthcare. People living with mental health (MH) conditions may have higher rates of chronic illness requiring surgical care but also face barriers to care. There is limited evidence about whether unequal surgical access contributes to health inequalities in this...
chronic conditions; cross-sectional study; epidemiology; health service research
2.334
79
Epidemiology; Psychiatry and Mental Health; Public Health, Environmental and Occupational Health
Medicine
2,024
38,494,856
Same-Day Discharge for Pediatric Hemithyroidectomy Patients: Evaluating Safety and Barriers to Discharge.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Otolaryngol Head Neck Surg
171
2
10.1002/ohn.726
eng
2,024
8
null
2,024
3
17
[OBJECTIVE] Hemithyroidectomy is often performed in the pediatric population for indeterminate or benign thyroid nodules. Prior studies confirmed the safety of same-day discharge for adults undergoing hemithyroidectomy or total thyroidectomy, but this has not been studied thoroughly in the pediatric population. Our goa...
barriers; hemithyroidectomy; outpatient; pediatric thyroid
0.987
150
Otorhinolaryngology; Surgery
Medicine
2,024
38,494,383
Interventions to improve patient admission and discharge practices in adult intensive care units: A systematic review.
Intensive critical care nursing
Intensive Crit Care Nurs
85
null
10.1016/j.iccn.2024.103688
eng
2,024
12
null
2,024
3
16
[OBJECTIVES] To identify and synthesise interventions and implementation strategies to optimise patient flow, addressing admission delays, discharge delays, and after-hours discharges in adult intensive care units. [METHODS] This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-A...
null
null
null
null
null
null
38,494,092
Deucrictibant for angioedema due to acquired C1-inhibitor deficiency: A randomized-controlled trial.
The Journal of allergy and clinical immunology
J Allergy Clin Immunol
154
1
10.1016/j.jaci.2024.03.007
eng
2,024
7
null
2,024
3
15
[BACKGROUND] Angioedema due to acquired C1-inhibitor deficiency is a very rare but serious disease, with an estimated prevalence of 1 per 500,000 persons. There are no approved therapies to treat or prevent angioedema swelling in patients with this condition. Deucrictibant is a specific, orally bioavailable, competitiv...
Deucrictibant; acquired C1-inhibitor deficiency; acute treatment; angioedema; bradykinin B2 receptor; long-term prophylaxis; randomized controlled trial
3.935
350
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
38,494,087
Readmission After Neonatal Intensive Care Unit Discharge: The Importance of Social Drivers of Health.
The Journal of pediatrics
J Pediatr
270
null
10.1016/j.jpeds.2024.114014
eng
2,024
7
null
2,024
3
15
[OBJECTIVE] To determine associations between sociodemographic and medical factors and odds of readmission after discharge from the neonatal intensive care unit for infants with very low birth weight (1500g). [STUDY DESIGN] Cohort study using linked data from the California Perinatal Quality Care Collaborative, Califor...
readmission; social drivers/determinants of health; very low birth weight infants
1.01
246
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,493,798
Insights into optimal surgical fixation for posterior malleolar fractures.
Bone joint open
Bone Jt Open
5
3
10.1302/2633-1462.53.BJO-2023-0133.R1
eng
2,024
3
18
2,024
3
18
[AIMS] The optimal management of posterior malleolar ankle fractures, a prevalent type of ankle trauma, is essential for improved prognosis. However, there remains a debate over the most effective surgical approach, particularly between screw and plate fixation methods. This study aims to investigate the differences in...
null
null
null
null
null
null
38,493,770
Place of concordance-discordance model in evaluating NGS performance.
Human heredity
Hum Hered
null
null
10.1159/000538401
eng
2,024
3
16
2,024
3
16
[INTRODUCTION] Ideally, evaluating NGS performance requires a gold standard; in its absence, concordance between replicates is often used as substitute standard. However, the appropriateness of the concordance-discordance criterion has been rarely evaluated. This study analyzes the relationship between the probability ...
null
0.484
66
Genetics; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,493,748
Evaluation of acute intravenous toxicity of HEPES: Is Good's buffer good and safe enough for clinical utilization in nuclear medicine?
Nuclear medicine and biology
Nucl Med Biol
132-133
null
10.1016/j.nucmedbio.2024.108895
eng
2,024
null
null
2,024
3
9
[OBJECTIVE] Good's buffer or HEPES has advantages over other buffers commonly used in radiopharmaceutical preparation as it exhibits significantly lower complexation tendency with metal ions. However, use of HEPES buffer for radiolabeling reactions, meant for clinical applications, has been underrated due to the non-av...
Good's buffer; HEPES; Lethal dose; MTD; Radiopharmaceuticals; Toxicity
0.742
100
Radiology, Nuclear Medicine and Imaging; Cancer Research; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,493,492
Living with a person with young onset dementia - spousal experience.
International journal of qualitative studies on health and well-being
Int J Qual Stud Health Well-being
19
1
10.1080/17482631.2024.2330233
eng
2,024
12
null
2,024
3
17
[PURPOSE] Being of working age while at the same time needing to help a partner with young onset dementia has specific consequences for spouses. Research to date has been sparse concerning this particular group of spouses. The aim of the study was to explore spouses' everyday experiences when living with a person with ...
Young onset dementia; emotional impact; everyday life; experience; spouse
0.764
51
Fundamentals and Skills; Issues, Ethics and Legal Aspects; Gerontology; Health Policy
Medicine; Nursing
2,024
38,493,363
Copy number variant risk loci for schizophrenia converge on the BDNF pathway.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
World J Biol Psychiatry
25
4
10.1080/15622975.2024.2327027
eng
2,024
4
null
2,024
5
1
[OBJECTIVES] Schizophrenia genetics is intricate, with common and rare variants' contributions not fully understood. Certain copy number variations (CNVs) elevate risk, pivotal for understanding mental disorder models. Despite CNVs' genome-wide distribution and variable gene and protein effects, we must explore beyond ...
Brain-derivedneurotrophic factor (BDNF); Functional genetics; Schizophrenia; copy number variations; molecular pathways
1.292
88
Medicine; Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,024
38,493,271
Evaluation of the relationship of treatment and vaccination with prognosis in patients with a diagnosis of COVID-19.
Inflammopharmacology
Inflammopharmacology
32
3
10.1007/s10787-024-01457-4
eng
2,024
6
null
2,024
3
16
[PURPOSE] Coronavirus disease 2019 (COVID-19) has affected millions of people worldwide and caused mortality. Many factors have been reported to affect the prognosis of COVID-19. In this study, we aimed to investigate the effects of drug therapy and vaccination on prognosis in patients hospitalized with a COVID-19 diag...
COVID; Chloroquine; Elderly; Favipiravir; Prognosis; Vaccine
1.269
74
Pharmacology; Pharmacology; Immunology
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,493,095
Integration of scRNA-seq data by disentangled representation learning with condition domain adaptation.
BMC bioinformatics
BMC Bioinformatics
25
1
10.1186/s12859-024-05706-9
eng
2,024
3
16
2,024
3
16
[BACKGROUND] The integration of single-cell RNA sequencing data from multiple experimental batches and diverse biological conditions holds significant importance in the study of cellular heterogeneity. [RESULTS] To expedite the exploration of systematic disparities under various biological contexts, we propose a scRNA-...
Cellular heterogeneity; Condition domain adaptation; Disentangled representation learning; Integration; ScRNA-seq; Variational autoencoder
1.19
251
Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
2,024
38,493,090
Involvement of Fgf2-mediated tau protein phosphorylation in cognitive deficits induced by sevoflurane in aged rats.
Molecular medicine (Cambridge, Mass.)
Mol Med
30
1
10.1186/s10020-024-00784-0
eng
2,024
3
16
2,024
3
16
[OBJECTIVE] Anesthetics have been linked to cognitive alterations, particularly in the elderly. The current research delineates how Fibroblast Growth Factor 2 (Fgf2) modulates tau protein phosphorylation, contributing to cognitive impairments in aged rats upon sevoflurane administration. [METHODS] Rats aged 3, 12, and ...
Aged rats; Cognitive impairment; Fgf2; Gsk3b; Sevoflurane; Tau protein phosphorylation; Transcriptomic sequencing
1.752
136
Genetics; Genetics; Molecular Biology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,492,997
A Molecular Typing Method for Invasive Breast Cancer by Serum Raman Spectroscopy.
Clinical breast cancer
Clin Breast Cancer
24
4
10.1016/j.clbc.2024.02.008
eng
2,024
6
null
2,024
2
16
[BACKGROUND] The incidence of breast cancer ranks highest among cancers and is exceedingly heterogeneous. Immunohistochemical staining is commonly used clinically to identify the molecular subtype for subsequent treatment and prognosis. [PURPOSE] Raman spectroscopy and support vector machine (SVM) learning algorithm we...
Breast carcinom; Liquid biopsy; Molecular subtype; Raman spectrum analysis; Support vector machine
1.018
85
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,492,802
Significantly reduced duration of antibiotic prescription for erysipelas subsequent to the 2019 French guidelines on skin and soft tissue infection: A before-after study.
Infectious diseases now
Infect Dis Now
54
3
10.1016/j.idnow.2024.104887
eng
2,024
4
null
2,024
3
15
[BACKGROUND] New skin and soft tissue infections (SSTI) guidelines were published in 2019 in France, changing the recommended duration for antibiotic treatment. The objective of the present study was to assess the impact of the publication of the 2019 French guidelines on SSTIs on the duration of antibiotic prescriptio...
Antibiotic duration; Cellulitis; Erysipelas; Guidelines; Skin and soft tissue infection
0.793
54
Infectious Diseases
Medicine
2,024
38,492,492
Self-rated health in old age, related factors and survival: A 20-Year longitudinal study within the Silver-MONICA cohort.
Archives of gerontology and geriatrics
Arch Gerontol Geriatr
122
null
10.1016/j.archger.2024.105392
eng
2,024
7
null
2,024
2
29
[INTRODUCTION] Self-rated health (SRH) offers insights into the evolving health demographics of an ageing population. [AIM] To assess change in SRH from old age to very old age and their associations with health and well-being factors, and to investigate the association between SRH and survival. [METHODS] All participa...
Aged 80 and over; Aging/psychology; Diagnostic self evaluation; Longitudinal studies; Population characteristics; Self-rated health; Survival analysis
1.282
102
Geriatrics and Gerontology; Gerontology; Health; Aging
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing; Social Sciences
2,024
38,491,485
Comparative analysis of stress distribution in residual roots with different canal morphologies: evaluating CAD/CAM glass fiber and other post-core materials.
BMC oral health
BMC Oral Health
24
1
10.1186/s12903-024-04109-9
eng
2,024
3
15
2,024
3
15
[BACKGROUND] The selection of post-core material holds significant importance in endodontically treated teeth, influencing stress distribution in the dental structure after restoration. The use of computer-aided design/computer-aided manufacturing (CAD/CAM) glass fiber post-core possesses a better adaptation for differ...
CAD/CAM; Dental materials; Fiber post; Finite element analysis; Post-and-core; Root canal
0.843
80
Dentistry
Dentistry
2,024
38,491,473
Relationship between physical activity and risk of depression in a married group.
BMC public health
BMC Public Health
24
1
10.1186/s12889-024-18339-7
eng
2,024
3
15
2,024
3
15
[BACKGROUND] Currently, there are many different findings on the relationship between physical activity and depression, and there may be differences between genders. This study therefore focused on gender differences to understand the relationship between physical activity behaviour and the risk of depression in marrie...
Both sexes; Depression risk; In-married group; Physical activity
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024