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38,674,882
Allergenic Shrimp Tropomyosin Distinguishes from a Non-Allergenic Chicken Homolog by Pronounced Intestinal Barrier Disruption and Downstream Th2 Responses in Epithelial and Dendritic Cell (Co)Culture.
Nutrients
Nutrients
16
8
10.3390/nu16081192
eng
2,024
4
17
2,024
4
17
[BACKGROUND] Tropomyosins (TM) from vertebrates are generally non-allergenic, while invertebrate homologs are potent pan-allergens. This study aims to compare the risk of sensitization between chicken TM and shrimp TM through affecting the intestinal epithelial barrier integrity and type 2 mucosal immune activation. [M...
epithelial barrier; food allergy; mucosal immunology; sensitizing allergenicity; tropomyosins
1.473
243
Food Science; Nutrition and Dietetics
Agricultural and Biological Sciences; Nursing
2,024
38,673,328
The Role of Climatic, Environmental and Socioeconomic Factors in the Natural Movement of Urban Populations in Kazakhstan, 2012-2020: An Analysis from a Middle-Income Country in Central Asia.
International journal of environmental research and public health
Int J Environ Res Public Health
21
4
10.3390/ijerph21040416
eng
2,024
3
29
2,024
3
29
[BACKGROUND] This study addresses the importance of identifying key characteristics influencing demographic indicators for urban populations, emphasizing the need to consider regional climatic features and ecological factors. The research utilized data from ten main regional cities across the Republic of Kazakhstan. [M...
Kazakhstan; central Asia; climate; demography; environment; middle-income country; public health; socioeconomic factors; urban population
0.919
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,024
38,724,904
The effect of fecal microbiota transplantation on antibiotic-associated diarrhea and its impact on gut microbiota.
BMC microbiology
BMC Microbiol
24
1
10.1186/s12866-024-03261-0
eng
2,024
5
9
2,024
5
9
[BACKGROUND] Antibiotic-associated diarrhea (AAD) refers to symptoms of diarrhea that cannot be explained by other causes after the use of antibiotics. AAD is thought to be caused by a disruption of intestinal ecology due to antibiotics. Fecal Microbiota Transplantation (FMT) is a treatment method that involves transfe...
Antibiotic-associated diarrhea; Dysbiosis; Efficacy; Fecal microbiota transplantation
1.032
147
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
38,724,721
Claudin-18 status and its correlation with HER2 and PD-L1 expression in gastric cancer with peritoneal dissemination.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Gastric Cancer
27
4
10.1007/s10120-024-01505-6
eng
2,024
7
null
2,024
5
9
[BACKGROUND] Gastric cancer with peritoneal dissemination (PD) has a dismal prognosis, and current treatments have shown little efficacy. CLDN18.2-targeted therapies have shown promising efficacy against gastric cancers that express high levels of CLDN18. Because of the limited information regarding CLDN18.2 status in ...
Claudin-18; Gastric cancer; Immunohistochemistry; Molecular targeted therapy; Peritoneal dissemination
2.489
106
Cancer Research; Gastroenterology; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,724,310
Visualization and Analysis of Vocal Fold Dynamics in Various Voice Disorders.
Journal of voice : official journal of the Voice Foundation
J Voice
null
null
10.1016/j.jvoice.2024.03.035
eng
2,024
5
8
2,024
5
8
[OBJECTIVES/HYPOTHESIS] This study aims to compare the glottal dynamics of vocal fold leukoplakia, laryngitis, and papilloma using various visualization techniques, including phonovibrograms (PVG) and glottovibrograms (GVG). It hypothesizes that these techniques can provide understanding of the vibratory dynamics of th...
Digital kymograms; Glottovibrograms; Laryngeal dynamics; Phonovibrograms; Visualization
0.573
114
LPN and LVN; Otorhinolaryngology; Speech and Hearing
Health Professions; Medicine; Nursing
2,024
38,724,060
Evaluation of adherence to pharmacological treatments by undocumented migrants with chronic diseases: a 10-year retrospective cohort study.
BMJ open
BMJ Open
14
5
10.1136/bmjopen-2023-078431
eng
2,024
5
9
2,024
5
9
[OBJECTIVES] To investigate the time course of medication adherence and some of the factors involved in this process in undocumented migrants with chronic diseases. [DESIGN] Retrospective cohort study. [SETTING] A big non-governmental organisation in Milano, Italy, giving medical assistance to undocumented migrants. [P...
cardiovascular disease; diabetes endocrinology; medication adherence; mental health
1.016
176
Medicine
Medicine
2,024
38,723,944
Ethical Incorporation of Artificial Intelligence into Neurosurgery: A Generative Pretrained Transformer Chatbot-Based, Human-Modified Approach.
World neurosurgery
World Neurosurg
187
null
10.1016/j.wneu.2024.04.165
eng
2,024
7
null
2,024
5
7
[INTRODUCTION] Artificial intelligence (AI) has become increasingly used in neurosurgery. Generative pretrained transformers (GPTs) have been of particular interest. However, ethical concerns regarding the incorporation of AI into the field remain underexplored. We delineate key ethical considerations using a novel GPT...
Bioethics; ChatGPT; Deep learning; Machine learning; Medical ethics; Neurologic surgery
0.709
123
Neurology; Surgery
Medicine
2,024
38,723,923
Ischemic stroke subtypes: risk factors, treatments, and 1-month prognosis - The Lille, France Stroke Registry.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
33
8
10.1016/j.jstrokecerebrovasdis.2024.107761
eng
2,024
8
null
2,024
5
7
[OBJECTIVES] First, this registry-based study aimed to comprehensively analyze patients' medical histories and treatments based on ischemic strokes' etiology. We focused on the management of atrial fibrillation among patients diagnosed with cardioembolic stroke. Then, our objective was to identify prognostic factors as...
Atrial fibrillation; Cardioembolic stroke; Ischemic stroke subtype; Mortality; Prognosis; Registry; Treatment
0.688
85
Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery
Medicine
2,024
38,723,444
Effect of arm position on image quality and radiation dose during thorax and abdomen computed tomography scans.
Radiography (London, England : 1995)
Radiography (Lond)
30
4
10.1016/j.radi.2024.04.015
eng
2,024
7
null
2,024
5
8
[INTRODUCTION] During Computed Tomography (CT) scans of the Thorax-Abdomen-Pelvis (TAP) the patient's arms should be positioned above the head to obtain optimal image quality and expose the patient to the lowest possible radiation dose. This may be impossible with patients with shoulder problems leading to arms being p...
Arm positioning; Computed tomography; Image noise; Image quality; Radiation dose
0.654
43
Research and Theory; Assessment and Diagnosis; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine; Nursing
2,024
38,723,328
Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients.
Journal of the neurological sciences
J Neurol Sci
461
null
10.1016/j.jns.2024.123026
eng
2,024
6
15
2,024
5
4
[BACKGROUND] Orthostatic hypotension (OH) is associated with an increased risk of dementia, potentially attributable to cerebral hypoperfusion. We investigated which patterns and characteristics of OH are related to cognition or to potentially underlying structural brain injury in hemodynamically impaired patients and ...
Atrophy; Blood pressure; Cerebral small vessel disease; Cognition; Orthostatic hypotension; White matter hyperintensities
1.145
158
Neurology; Neurology
Medicine; Neuroscience
2,024
38,723,103
Single-test syphilis serology: A case of not seeing the forest for the trees.
PloS one
PLoS One
19
5
10.1371/journal.pone.0303253
eng
2,024
null
null
2,024
5
9
[INTRODUCTION] There have been few empirical studies for diagnostic test accuracy of syphilis using a sequence of rapid tests in populations with low prevalence of syphilis such as pregnant women. This analysis describes syphilis test positivity frequency among pregnant women at an antenatal clinic in Zambia using a re...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
38,722,847
Proportions and determinants of successful surgical repair of obstetric fistula in low- and middle-income countries: A systematic review and meta-analysis.
PloS one
PLoS One
19
5
10.1371/journal.pone.0303020
eng
2,024
null
null
2,024
5
9
[BACKGROUND] Obstetric fistula is a serious and debilitating problem resulting from tissue necrosis on the reproductive and urinary and/or lower gastrointestinal tract organs due to prolonged labor. Primary studies of the treatment of obstetric fistulae report significantly variable treatment outcomes following surgica...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
38,722,739
Feeding Tube Clinic Effect on Nutrition.
Surgical laparoscopy, endoscopy percutaneous techniques
Surg Laparosc Endosc Percutan Tech
34
4
10.1097/SLE.0000000000001277
eng
2,024
8
1
2,024
8
1
[BACKGROUND] Optimizing nutrition is essential for recovery after major surgery or severe illness. Feeding tubes (FT) can be placed in patients limited by oral enteral nutrition. Given the myriad of locations in which these procedures are performed (radiology, intensive care unit, and endoscopy suite), routine follow-u...
null
null
null
null
null
null
38,722,732
The Effects of a Cool Saline Solution Irrigation on Mandibular Third Molar Extraction Site: A Postoperative Split-Mouth Evaluation.
The Journal of craniofacial surgery
J Craniofac Surg
35
4
10.1097/SCS.0000000000010241
eng
2,024
6
1
2,024
5
9
[OBJECTIVE] This study aimed to evaluate the effects of sterile saline solution irrigation (lavage) performed after mandibular third molar extraction on postoperative complications, utilizing a split-mouth randomized clinical trial design. [METHODS] Seventeen healthy participants requiring bilateral mandibular third mo...
null
0.437
90
Otorhinolaryngology; Surgery; Medicine
Medicine
2,024
38,722,664
Dose-Adjusted EPOCH Plus Inotuzumab Ozogamicin in Adults With Relapsed or Refractory B-Cell ALL: A Phase 1 Dose-Escalation Trial.
JAMA oncology
JAMA Oncol
10
7
10.1001/jamaoncol.2024.0967
eng
2,024
7
1
null
null
null
[IMPORTANCE] Options for adults with relapsed or refractory B-cell acute lymphoblastic leukemia or lymphoma (B-ALL) are limited, and new approaches are needed. Inotuzumab ozogamicin (InO) has been combined with low-intensity chemotherapy, with modest improvements over historical controls, and dose-adjusted etoposide, p...
null
null
null
null
null
null
38,722,442
Long-term prospective outcome data using EndoPredict as risk stratification and chemotherapy decision biomarker in hormone receptor-positive, HER2-negative early breast cancer.
Breast cancer research and treatment
Breast Cancer Res Treat
207
1
10.1007/s10549-024-07346-2
eng
2,024
8
null
2,024
5
9
[PURPOSE] To report the prospective long-term outcome data of patients whose chemotherapy decision was guided by the EndoPredict test. [METHODS] Patients with hormone receptor-positive HER2-negative early breast cancer with 0-3 positive lymph nodes were enrolled. The EndoPredict test was carried out on all tumor sample...
Adjuvant chemotherapy; Breast cancer; EndoPredict; Predictive biomarker; Prognostic biomarker; Risk stratification
1.351
184
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,722,350
Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers.
European journal of clinical pharmacology
Eur J Clin Pharmacol
80
9
10.1007/s00228-024-03697-3
eng
2,024
9
null
2,024
5
9
[PURPOSE] Currently, body weight-based dosing of rifampicin is recommended. But lately, fat-free mass (FFM) was reported to be superior to body weight (BW). The present evaluation aimed to assess the influence of body mass-related covariates on rifampicin's pharmacokinetics (PK) parameters in more detail using non-line...
Body weight; Covariate modeling; Fat-free mass; Population pharmacokinetics; Rifampicin
0.849
126
Medicine; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,722,267
Tectorigenin inhibits inflammatory responses in murine inflammatory bowel disease and LPS-stimulated macrophages via inactivating MAPK signaling pathway.
Immunity, inflammation and disease
Immun Inflamm Dis
12
5
10.1002/iid3.1077
eng
2,024
5
null
null
null
null
[BACKGROUND] Considering the antihepatitis effects of Tectorigenin (TEC), and the same adenosine mitogen-activated protein kinase (MAPK) pathway in both hepatitis and inflammatory bowel disease (IBD) models, exploring the role of TEC in IBD is contributive to develop a new treatment strategy against IBD. [METHODS] The ...
IBD; LPS; MAPK signaling pathway; macrophages; tectorigenin
0.814
38
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
38,721,523
Sleep Duration Irregularity is Associated with Elevated Blood Pressure During Submaximal Exercise in Young Adults.
Nature and science of sleep
Nat Sci Sleep
16
null
10.2147/NSS.S460212
eng
2,024
null
null
2,024
5
2
[PURPOSE] Irregularity in nightly sleep duration is reported to associate with elevated blood pressure (BP), but it is unclear whether this association can be observed with BP measured during exercise after controlling for factors known to influence the exercise pressor reflex. [METHODS] Twenty-nine young adults (22±4y...
VO2; blood pressure; chronotype; exercise; sleep duration; sleep variability
1.154
55
Behavioral Neuroscience; Applied Psychology
Neuroscience; Psychology
2,024
38,721,522
Semaphorin 7A impairs barrier function in cultured human corneal epithelial cells in a manner dependent on nuclear factor-kappa B.
International journal of ophthalmology
Int J Ophthalmol
17
3
10.18240/ijo.2024.03.05
eng
2,024
null
null
2,024
3
18
[AIM] To evaluate the role of semaphorin 7A (Sema7A) and its associated regulatory mechanisms in modulating the barrier function of cultured human corneal epithelial cells (HCEs). [METHODS] Barrier models of HCEs were treated with recombinant human Sema7A at concentrations of 0, 125, 250, or 500 ng/mL for 24, 48, or 72...
barrier function; human corneal epithelial; nuclear factor-kappa B; occludin; transepithelial electrical resistance; zonula occludens-1
0.544
48
Ophthalmology
Medicine
2,024
38,721,046
Trends and hotspots in acupuncture treatment of rat models of stroke: a bibliometric analysis from 2004 to 2023.
Frontiers in neuroscience
Front Neurosci
18
null
10.3389/fnins.2024.1383283
eng
2,024
null
null
2,024
4
24
[BACKGROUND] Acupuncture is a widely used clinical treatment method, and studies have confirmed its therapeutic effects on stroke patients. It can also reduce the burden on patients and society. Acupuncture treatment is a complementary and preventive treatment for stroke. However, there has yet to be a visual bibliomet...
acupuncture; bibliometric analysis; rat model; stroke; web of science
1.068
170
Neuroscience
Neuroscience
2,024
38,721,020
Malignant peritoneal mesothelioma presenting with bilateral hydronephrosis and renal insufficiency: a case report and literature review.
Frontiers in surgery
Front Surg
11
null
10.3389/fsurg.2024.1342657
eng
2,024
null
null
2,024
4
24
[INTRODUCTION] Malignant peritoneal mesothelioma (MPM) is an extremely rare tumor with nonspecific clinical manifestations, making diagnosis challenging. [CASE PRESENTATION] Herein, we report a case of MPM with occult onset presenting with bilateral hydronephrosis and renal insufficiency. A 30-year-old man was admitted...
case report; hydronephrosis; percutaneous nephrostomy; peritoneal mesothelioma; ureteral stent
0.541
48
Surgery
Medicine
2,024
38,720,927
An electrochemical sensor based on a modified glassy carbon electrode for detection of epinephrine in the presence of theophylline.
ADMET DMPK
ADMET DMPK
12
2
10.5599/admet.2082
eng
2,024
null
null
2,024
4
15
[BACKGROUND AND PURPOSE] Neurotransmitters are chemical messengers that enhance and balance signals between cells and target cells in the body. They are vital to the body's ability to function. Epinephrine is one of the most essential catecholamine neurotransmitters with an important biological and pharmacological role...
CeO2-ZnO nanocomposite; modified electrode; sensing platform; voltammetry
null
null
null
null
null
38,720,787
Loose-patch clamp analysis applied to voltage-gated ionic currents following pharmacological ryanodine receptor modulation in murine hippocampal cornu ammonis-1 pyramidal neurons.
Frontiers in physiology
Front Physiol
15
null
10.3389/fphys.2024.1359560
eng
2,024
null
null
2,024
4
24
[INTRODUCTION] The loose-patch clamp technique was first developed and used in native amphibian skeletal muscle (SkM), offering useful features complementing conventional sharp micro-electrode, gap, or conventional patch voltage clamping. It demonstrated the feedback effects of pharmacological modification of ryanodine...
caffeine; cyclopiazonic acid; dantrolene; hippocampal pyramidal neurons; ryanodine receptors; voltage-gated channels
1.023
175
Physiology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,720,370
Deep learning imaging phenotype can classify metabolic syndrome and is predictive of cardiometabolic disorders.
Journal of translational medicine
J Transl Med
22
1
10.1186/s12967-024-05163-1
eng
2,024
5
8
2,024
5
8
[BACKGROUND] Cardiometabolic disorders pose significant health risks globally. Metabolic syndrome, characterized by a cluster of potentially reversible metabolic abnormalities, is a known risk factor for these disorders. Early detection and intervention for individuals with metabolic abnormalities can help mitigate the...
Computed tomography; Deep learning; Machine learning; Metabolic syndrome
1.997
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,720,369
Presentation of enthesitis-related arthritis and juvenile-onset spondyloarthritis: a cross-sectional study in a pediatric and adult clinic.
Advances in rheumatology (London, England)
Adv Rheumatol
64
1
10.1186/s42358-024-00378-8
eng
2,024
5
8
2,024
5
8
[BACKGROUND] Juvenile idiopathic arthritis (JIA) comprises a whole spectrum of chronic arthritis starting before 16 years of age. The study aims to explore the clinical and demographic descriptors, treatment, and disease progression of enthesitis-related arthritis (ERA) in comparison with juvenile-onset spondyloarthrit...
Classification; Enthesitis-related arthritis; Juvenile idiopathic arthritis; Outcome; Spondyloarthritis; Spondyloarthropathy
0.645
43
Rheumatology
Medicine
2,024
38,720,274
Association between NDUFS1 from urinary extracellular vesicles and decreased differential renal function in children with ureteropelvic junction obstruction.
BMC nephrology
BMC Nephrol
25
1
10.1186/s12882-024-03592-0
eng
2,024
5
8
2,024
5
8
[BACKGROUND] Ureteropelvic junction obstruction (UPJO) is the most common cause of pediatric congenital hydronephrosis, and continuous kidney function monitoring plays a role in guiding the treatment of UPJO. In this study, we aimed to explore the differentially expressed proteins (DEPs) in the urinary extracellular ve...
Differential renal function; NDUFS1; Ureteropelvic junction obstruction; Urinary extracellular vesicles
0.805
83
Nephrology
Medicine
2,024
38,720,247
A comparison of RNA-Seq data preprocessing pipelines for transcriptomic predictions across independent studies.
BMC bioinformatics
BMC Bioinformatics
25
1
10.1186/s12859-024-05801-x
eng
2,024
5
8
2,024
5
8
[BACKGROUND] RNA sequencing combined with machine learning techniques has provided a modern approach to the molecular classification of cancer. Class predictors, reflecting the disease class, can be constructed for known tissue types using the gene expression measurements extracted from cancer patients. One challenge o...
Batch effect correction; Cancer; Classification; Data scaling; Normalization; RNA-Seq
1.19
251
Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
2,024
38,719,630
Impact of coronary artery disease and revascularization on outcomes of transcatheter aortic valve replacement for severe aortic stenosis.
Cardiovascular revascularization medicine : including molecular interventions
Cardiovasc Revasc Med
68
null
10.1016/j.carrev.2024.05.003
eng
2,024
11
null
2,024
5
5
[BACKGROUND/PURPOSE] To evaluate the impact of coronary artery disease (CAD), percutaneous coronary intervention (PCI), and coronary lesion complexity on outcomes of transcatheter aortic valve replacement (TAVR) for aortic stenosis. [METHODS/MATERIALS] This retrospective study included 1042 patients divided into two gr...
Aortic valve; Instantaneous wave-free ratio; Transcatheter valve therapy
0.613
47
Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,024
38,719,505
Effects of metformin, saxagliptin and repaglinide on gut microbiota in high-fat diet/streptozocin-induced type 2 diabetic mice.
BMJ open diabetes research care
BMJ Open Diabetes Res Care
12
3
10.1136/bmjdrc-2023-003837
eng
2,024
5
6
2,024
5
6
[INTRODUCTION] There has been increasing evidence that the gut microbiota is closely related to type 2 diabetes (T2D). Metformin (Met) is often used in combination with saxagliptin (Sax) and repaglinide (Rep) for the treatment of T2D. However, little is known about the effects of these combination agents on gut microbi...
Diabetes Mellitus, Type 2; Metformin; Microbiology; Type 2 Diabetes
null
null
null
null
null
38,719,316
Predictors of somatic symptoms during the COVID-19 pandemic: a national longitudinal survey in Japan.
BMJ open
BMJ Open
14
5
10.1136/bmjopen-2023-082439
eng
2,024
5
7
2,024
5
7
[OBJECTIVES] The COVID-19 pandemic has highlighted the long-term consequences of SARS-CoV-2 infection, termed long COVID. However, in the absence of comparative groups, the differentiation of disease progression remains difficult, as COVID-19 symptoms become indistinguishable from symptoms originating from alternative ...
COVID-19; EPIDEMIOLOGY; Public health
1.016
176
Medicine
Medicine
2,024
38,719,213
Zinc for prevention and treatment of the common cold.
The Cochrane database of systematic reviews
Cochrane Database Syst Rev
5
5
10.1002/14651858.CD014914.pub2
eng
2,024
5
9
2,024
5
9
[BACKGROUND] The common cold is an acute, self-limiting viral respiratory illness. Symptoms include nasal congestion and mucus discharge, sneezing, sore throat, cough, and general malaise. Given the frequency of colds, they are a public health burden and a significant cause of lost work productivity and school absentee...
null
1.623
341
Medicine; Pharmacology
Medicine
2,024
38,718,980
Sarcopenia measured by tomography as a predictor of morbidity and mortality in thoracic surgery, a retrospective cohort study.
Revista espanola de anestesiologia y reanimacion
Rev Esp Anestesiol Reanim (Engl Ed)
71
7
10.1016/j.redare.2024.05.001
eng
2,024
null
null
2,024
5
6
[BACKGROUND] Sarcopenia has been identified as a risk factor for perioperative adverse events. Several studies have shown that tomographic assessment of muscle mass can be an appropriate indicator of sarcopenia associated with morbidity and mortality. The aim of the study was to determine the association between height...
Mortalidad; Mortality; Outcomes; Resultados; Sarcopenia; Thoracic surgery; Tomography
0.273
29
Anesthesiology and Pain Medicine; Critical Care and Intensive Care Medicine
Medicine
2,024
38,718,978
Navigating Public Policy Responses to a Pandemic: The Balancing Act Between Physical Health, Mental Health, and Household Income.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Value Health
27
8
10.1016/j.jval.2024.04.019
eng
2,024
8
null
2,024
5
6
[OBJECTIVE] During COVID-19, governments imposed restrictions that reduced pandemic-related health risks but likely increased personal and societal mental health risk, partly through reductions in household income. This study aimed to quantify the public's willingness to accept trade-offs between pandemic health risks,...
discrete choice; mental health; pandemic; trade-offs; willingness to accept
1.856
138
Health Policy; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
38,718,850
Endovascular therapy versus bypass for chronic limb-threatening ischemia in a real-world practice.
Journal of vascular surgery
J Vasc Surg
80
4
10.1016/j.jvs.2024.04.067
eng
2,024
10
null
2,024
5
6
[OBJECTIVE] The recent Best Endovascular vs Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) study showed that bypass was superior to endovascular therapy (ET) in patients with chronic limb-threatening ischemia (CLTI) deemed suitable for either approach who had an available single-segment great ...
Bypass; Chronic limb-threatening ischemia; Endovascular therapy; Graft; Great saphenous vein
2.075
225
Cardiology and Cardiovascular Medicine; Surgery
Medicine
2,024
38,718,061
Neonatal sepsis in a tertiary health facility in Cape Coast, Ghana.
PloS one
PLoS One
19
5
10.1371/journal.pone.0302533
eng
2,024
null
null
2,024
5
8
[BACKGROUND] Neonatal Sepsis remains a significant burden globally, accounting for over 2.5 million neonatal deaths annually, with low-and middle-income countries (LMIC) including Ghana disproportionately affected. The current study sought to ascertain the prevalence of neonatal sepsis and associated factors based on a...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
38,717,170
Preoperative anxiety in the paediatric population in a tertiary hospital: A descriptive cross-sectional study.
Journal of perioperative practice
J Perioper Pract
null
null
10.1177/17504589241239196
eng
2,024
5
8
2,024
5
8
[AIM] To analyse preoperative paediatric anxiety in a tertiary hospital and influencing factors. [DESIGN AND METHODS] This study was designed as a descriptive cross-sectional study. One hundred patients between two and 12 years old who underwent elective surgical intervention were included. All patients received oral o...
Anxiety; Nursing; Paediatrics; Postoperative care
null
null
null
null
null
38,716,944
Molecular monitoring by CDKN2A/p16INK4A and RB1 gene methylation in breast cancer.
Revista da Associacao Medica Brasileira (1992)
Rev Assoc Med Bras (1992)
70
4
10.1590/1806-9282.20231358
eng
2,024
null
null
2,024
5
3
[OBJECTIVE] This prospective study aimed to provide a comprehensive analysis of the methylation status of two pivotal genes, CDKN2A/p16INK4A (cyclin-dependent kinase inhibitor 2A) and RB1 (retinoblastoma transcriptional corepressor 1), in breast cancer patients. [METHODS] Samples were obtained from 15 women diagnosed w...
null
0.319
51
Medicine
Medicine
2,024
38,716,936
Factors of mortality in patients with cardiac implantable electronic device: 5-year experience.
Revista da Associacao Medica Brasileira (1992)
Rev Assoc Med Bras (1992)
70
4
10.1590/1806-9282.20230998
eng
2,024
null
null
2,024
5
3
[OBJECTIVE] The use of cardiac implantable electronic devices has increased in recent years. It has also brought some issues. Among these, the complications of cardiac implantable electronic devices infection and pocket hematoma are difficult to manage. It can be fatal with the contribution of patient-related risk fact...
null
0.319
51
Medicine
Medicine
2,024
38,716,630
Barriers to physical activity participation for adults with intellectual disability: A cross-sectional study.
Journal of applied research in intellectual disabilities : JARID
J Appl Res Intellect Disabil
37
4
10.1111/jar.13242
eng
2,024
7
null
null
null
null
[BACKGROUND] Identifying barriers that can be modified to promote physical activity is important for informing health interventions for adults with intellectual disabilities. [OBJECTIVES] Exploring participation in physical activity considering age, sex, living conditions, and health conditions. Further, identifying ba...
barriers; exercise; health; intellectual disability; physical activity
0.946
79
Education; Developmental and Educational Psychology
Psychology; Social Sciences
2,024
38,716,462
RANGE OF MOTION AFTER BONE BLOCK PROCEDURES FOR SHOULDER INSTABILITY: SYSTEMATIC REVIEW.
Acta ortopedica brasileira
Acta Ortop Bras
32
spe1
10.1590/1413-785220243201e273366
eng
2,024
null
null
2,024
5
6
[OBJECTIVE] to determine the surgical indications for glenoid bone grafting associated with better postoperative ranges of motion. [METHODS] This systematic review was conducted according to PRISMA. The included studies were subdivided according to the criteria used to indicate glenoid bone graft surgery: group for rad...
Orthopedic Surgery; Shoulder; Systematic Review
0.253
30
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation
Health Professions; Medicine
2,024
38,716,420
Effect of 0.01% atropine combined with orthokeratology lens on axial elongation: a 2-year randomized, double-masked, placebo-controlled, cross-over trial.
Frontiers in medicine
Front Med (Lausanne)
11
null
10.3389/fmed.2024.1358046
eng
2,024
null
null
2,024
4
23
[PURPOSE] To evaluate the effect of 0.01% atropine combined with orthokeratology (OK) lens on axial elongation in schoolchildren with myopia. [METHODS] Sixty children aged 8-12 years with spherical equivalent refraction (SER) from -1.00D to -4.00D in both eyes were enrolled in this randomized, double-masked, placebo-co...
0.01% atropine; axial length; myopia; orthokeratology; schoolchildren
0.962
102
Medicine
Medicine
2,024
38,716,372
Erectile Dysfunction and Depression Prevalence Among Male Patients with Type II Diabetes.
Journal of multidisciplinary healthcare
J Multidiscip Healthc
17
null
10.2147/JMDH.S455089
eng
2,024
null
null
2,024
5
3
[BACKGROUND AND OBJECTIVE] Patients with Type 2 Diabetes (T2D) are at substantial risk for developing erectile dysfunction (ED). The primary goal of this study was to assess the prevalence of ED and depression among T2D patients and the associated risk factors. [METHODS] A cross-sectional study was conducted for adult ...
ED; T2D; depression; diabetes; erectile dysfunction; risk factors
0.773
60
Nursing; Medicine
Medicine; Nursing
2,024
38,715,814
Accuracy of mapping results of thoracolumbar vertebral fracture verified using finite element analysis.
American journal of translational research
Am J Transl Res
16
4
10.62347/BVDL1541
eng
2,024
null
null
2,024
4
15
[OBJECTIVE] To verify the results of three-dimensional fracture mapping of T12-L2 compression fractures by the finite element method from a biomechanical point of view, and to provide clinical reference. [METHODS] This study is a retrospective study. By collecting 150 patients' computerized tomography (CT) data with th...
Spinal fracture; finite element analysis; fracture line distribution; fracture map; thoracolumbar fracture
null
null
null
null
null
38,715,664
Histone H3 trimethylation on lysine 27 immunostaining pattern in DICER1-associated tumors.
Translational pediatrics
Transl Pediatr
13
4
10.21037/tp-24-61
eng
2,024
4
30
2,024
4
28
[BACKGROUND] DICER1-associated tumors are heterogeneous and affect several organs. DICER1-associated primary intracranial sarcoma is associated with histone H3 trimethylation on lysine 27 (H3K27me3) loss in nucleus by immunohistochemistry. [METHODS] We explored the H3K27me3 immunostaining pattern in other DICER1-associ...
DICER1; Sertoli-Leydig cell tumor; histone H3 trimethylation on lysine 27 (H3K27me3); immunohistochemistry; pleuropulmonary blastoma (PPB)
0.606
37
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,715,556
The Determinants of Eosinophilia in Patients With Severe Asthma.
Journal of clinical medicine research
J Clin Med Res
16
4
10.14740/jocmr5162
eng
2,024
4
null
2,024
4
30
[BACKGROUND] Asthma is defined by the Global Initiative for Asthma (GINA) as a heterogeneous disease characterized by chronic airway inflammation. The pathogenesis of the disease is better understood with the comprehension of immunological pathways. These pathways differ by the type of recruited cells and released inte...
Allergy; Asthma; Atopy; Eosinophilia; Eosinophilic asthma; Immune pathways; Steroid use
0.53
26
Medicine
Medicine
2,024
38,715,472
Molecular insights into expression and silencing of resistance determinants in Staphylococcus aureus.
Tropical medicine international health : TM IH
Trop Med Int Health
29
6
10.1111/tmi.14000
eng
2,024
6
null
2,024
5
8
[OBJECTIVE] This study aimed to investigate the status of antimicrobial-resistant strains of Staphylococcus aureus in Pakistan, their association in terms of co-occurrence with the biofilm-forming genes, resistance profiling and associated discrepancies in diagnostic methods. [METHODOLOGY] A total of 384 milk samples f...
S. aureus; antimicrobial resistance; biofilm; discrepancies
null
null
null
null
null
38,715,073
Vaginal leiomyoma in a goat expressing the nuclear progesterone receptor (PGR): a case report.
BMC veterinary research
BMC Vet Res
20
1
10.1186/s12917-024-04035-6
eng
2,024
5
7
2,024
5
7
[BACKGROUND] The risk of developing tumorous diseases in the genital tract also increases with age in animals. One of the classified tumor types is genital leiomyoma. Presently, our understanding of the pathogenesis of this tumor in goats is, however, limited. This accounts also for the information regarding the presen...
Goat; Reproductive disorder; Sex steroid hormone; Vaginal discharge; Vaginal tumor
0.723
86
Veterinary; Medicine
Medicine; Veterinary
2,024
38,715,024
Usability of Standards for Scaffolding in a Health Sciences Programme: A feasibility Study.
BMC nursing
BMC Nurs
23
1
10.1186/s12912-024-01975-0
eng
2,024
5
7
2,024
5
7
[BACKGROUND] Standards contribute to comprehensive and programmatic implementation of educational strategies, such as scaffolding. Although the development of educational standards follows a rigorous consensus approach, they are socially constructed and could result in varied interpretations by users. Reports of varied...
Feasibility; Health Sciences Programme; Nursing; Pilot study; Scaffolding; Standards; Usability
1.272
62
Nursing
Nursing
2,024
38,714,946
Impact of interventions to reduce nosocomial transmission of SARS-CoV-2 in English NHS Trusts: a computational modelling study.
BMC infectious diseases
BMC Infect Dis
24
1
10.1186/s12879-024-09330-z
eng
2,024
5
7
2,024
5
7
[BACKGROUND] Prior to September 2021, 55,000-90,000 hospital inpatients in England were identified as having a potentially nosocomial SARS-CoV-2 infection. This includes cases that were likely missed due to pauci- or asymptomatic infection. Further, high numbers of healthcare workers (HCWs) are thought to have been inf...
Agent-based model; Healthcare-associated infection; IPC; Individual-based model; Infection prevention and control; Masking
1.035
137
Infectious Diseases
Medicine
2,024
38,714,548
Cricopharyngeus muscle dysfunction: a poorly defined disorder from diagnosis to treatment.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Eur Arch Otorhinolaryngol
281
9
10.1007/s00405-024-08644-7
eng
2,024
9
null
2,024
5
7
[PURPOSE] Cricopharyngeus muscle dysfunction (CPMD) is a common clinical occurrence with very few clear diagnostic criteria and multiple pathways for treatment. Incidence of CPMD is not known, but some data suggest around 25% of people with dysphagia experience some degree of CPMD, which negatively impacts swallowing s...
Cricopharyngeus; Laryngology; Swallowing; Treatment
0.787
94
Otorhinolaryngology; Medicine
Medicine
2,024
38,714,323
Comparative effectiveness of tildrakizumab 200 mg versus tildrakizumab 100 mg in psoriatic patients with high disease burden or above 90 kg of body weight: a 16-week multicenter retrospective study - IL PSO (Italian landscape psoriasis).
The Journal of dermatological treatment
J Dermatolog Treat
35
1
10.1080/09546634.2024.2350760
eng
2,024
12
null
2,024
5
7
[PURPOSE] Tildrakizumab is a selective inhibitor of IL-23 approved for the treatment of moderate-to-severe plaque psoriasis in two dosages. We conducted a 16-week multicenter retrospective study to compare the effectiveness and safety of tildrakizumab 200 mg versus tildrakizumab 100 mg in patients with a high disease b...
Biologics; psoriasis; psoriasis treatment; tildrakizumab
1.067
69
Dermatology
Medicine
2,024
38,713,923
Dysregulation of peripheral and intratumoral KLRG1[+] CD8[+]T cells is associated with immune evasion in patients with non-small-cell lung cancer.
Translational oncology
Transl Oncol
45
null
10.1016/j.tranon.2024.101968
eng
2,024
7
null
2,024
5
7
[OBJECTIVES] Killer cell lectin like receptor G1 (KLRG1) is identified as a co-inhibitory receptor for NK cells and antigen-experienced T cells. The role of KLRG1 in immune regulation in patients with non-small cell lung cancer (NSCLC) remains poorly understood. [MATERIALS AND METHODS] We measured the proportion and im...
E-cadherin; Immunotherapy target; KLRG1; Non-small cell lung cancer; Tumor immune evasion
1.408
78
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,713,736
Effects of a choral program combining wind instrument performance and breathing training on respiratory function, stress, and quality of life in adolescents: A randomized controlled trial.
PloS one
PLoS One
19
5
10.1371/journal.pone.0276568
eng
2,024
null
null
2,024
5
7
[BACKGROUND] Choral activities are correlated with various health and wellbeing parameters. However, an intervention combining a music program using wind instruments and choral activities has not yet been investigated. Thus, this study aimed to assess the effects of a 12-week intervention combining a wind instrument pe...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
38,713,682
Sex differences in health-related quality of life and poverty risk among older people living with HIV in Spain: A cross-sectional study.
PloS one
PLoS One
19
5
10.1371/journal.pone.0301335
eng
2,024
null
null
2,024
5
7
[BACKGROUND] Current antiretroviral therapies have increased the life expectancy of people living with HIV (PLHIV). There is, however, limited evidence regarding the health-related quality of life (HRQoL) and living conditions of older people living with HIV (OPLHIV) in Spain. [METHODS] We implemented a self-administer...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
38,713,489
Operating Room Waste Generated From Corneal and Conjunctival Surgeries.
Cornea
Cornea
43
8
10.1097/ICO.0000000000003560
eng
2,024
8
1
2,024
5
7
[PURPOSE] The purposes of this study were to bring awareness to the surgical waste generated from corneal and conjunctival surgeries and to compare those findings with the waste generated from cataract surgeries. [METHODS] This was an observational prospective pilot cohort study at a tertiary corneal/anterior segment p...
null
0.955
141
Ophthalmology
Medicine
2,024
38,713,371
Beliefs and Perceptions of Physical Activity Among Black Adolescents in South Florida: A Qualitative Study.
Journal of racial and ethnic health disparities
J Racial Ethn Health Disparities
12
3
10.1007/s40615-024-02016-x
eng
2,025
6
null
2,024
5
7
[INTRODUCTION] In the United States, non-Hispanic Black adolescents have a significantly higher prevalence of obesity than their peers. Though physical activity (PA) has many benefits, many adolescents fail to engage in adequate amounts of PA. Black adolescents are also more sedentary than those from other races and et...
African American; Focus groups; Physical activity; Theory of Planned Behavior; Youth
1.46
56
Anthropology; Health Policy; Health; Public Health, Environmental and Occupational Health; Sociology and Political Science
Medicine; Social Sciences
2,024
38,713,274
Impact of COVID-19 Infection on Pancreato-Biliary Diseases Requiring Endoscopic Retrograde Cholangiopancreatography.
Digestive diseases and sciences
Dig Dis Sci
69
8
10.1007/s10620-024-08454-1
eng
2,024
8
null
2,024
5
7
[BACKGROUND] Viral infections are known to impact the pancreato-biliary system; however, there are limited data showing that the same is true of COVID-19. Endoscopic retrograde cholangiopancreatography (ERCP) can safely be performed in patients with COVID-19 infection, but outcomes of patients with COVID-19 infections ...
COVID; ERCP; Endoscopic intervention; Endoscopic retrograde cholangiopancreatography; Pancreatico-biliary; Pancreatitis
1.004
146
Gastroenterology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,713,217
Long-term survival after anti-PD-1 discontinuation in advanced cutaneous squamous cell carcinoma (cSCC): a proof of concept of benefit of concomitant cemiplimab and radiotherapy.
Cancer immunology, immunotherapy : CII
Cancer Immunol Immunother
73
7
10.1007/s00262-024-03700-x
eng
2,024
5
7
2,024
5
7
[BACKGROUND] In a princeps study we conducted in patients with advanced cutaneous squamous cell carcinoma treated with concomitant anti-Programmed cell death protein 1 (PD-1) and radiotherapy, we demonstrated a clinico radiological response to cemiplimab that appeared to persist over time, 1 year after treatment discon...
Cemiplimab discontinuation; Cutaneous squamous cell carcinoma; Immunotherapy
1.716
142
Cancer Research; Immunology; Immunology and Allergy; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
38,713,105
FLT4 causes developmental disorders of the cardiovascular and lymphovascular systems via pleiotropic molecular mechanisms.
Cardiovascular research
Cardiovasc Res
120
10
10.1093/cvr/cvae104
eng
2,024
9
2
null
null
null
[AIMS] Rare, deleterious genetic variants in FLT4 are associated with Tetralogy of Fallot (TOF), the most common cyanotic congenital heart disease. The distinct genetic variants in FLT4 are also an established cause of Milroy disease, the most prevalent form of primary hereditary lymphoedema. The phenotypic features of...
Congenital heart disease; Developmental pleiotropy; FLT4; Primary lymphoedema; Proteostasis; Tetralogy of Fallot; VEGFR3
null
null
null
null
null
38,713,006
Evaluating site-of-care-related racial disparities in kidney graft failure using a novel federated learning framework.
Journal of the American Medical Informatics Association : JAMIA
J Am Med Inform Assoc
31
6
10.1093/jamia/ocae075
eng
2,024
5
20
null
null
null
[OBJECTIVES] Racial disparities in kidney transplant access and posttransplant outcomes exist between non-Hispanic Black (NHB) and non-Hispanic White (NHW) patients in the United States, with the site of care being a key contributor. Using multi-site data to examine the effect of site of care on racial disparities, the...
federated learning; kidney transplant; racial disparities; registry data
2.039
184
Health Informatics
Medicine
2,024
38,712,801
Recalcitrant dermatophyte infections: identification and risk factors.
International journal of dermatology
Int J Dermatol
63
10
10.1111/ijd.17145
eng
2,024
10
null
2,024
5
7
[INTRODUCTION] Recalcitrant dermatophytosis is an emerging phenomenon that occurs worldwide, and Trichophyton indotineae is currently the prominent cause. [MATERIALS AND METHODS] Skin specimens from patients with tinea infection were obtained by scrubbing and then sectioned into three fragments. Two fragments were subj...
recalcitrant dermatophytosis; risk factors; skin specimens; tinea corporis; tinea cruris
0.822
111
Dermatology
Medicine
2,024
38,712,361
Efficacy of serum leucine-rich alpha-2 glycoprotein in predicting findings of Crohn's disease small bowel lesion in capsule endoscopy.
Intestinal research
Intest Res
22
4
10.5217/ir.2023.00139
eng
2,024
10
null
2,024
5
7
[BACKGROUND/AIMS] Small bowel capsule endoscopy (SBCE) is an evaluation method for small bowel (SB) lesions in Crohn's disease (CD). However, the relationship between SBCE findings and the serological biomarker leucine-rich alpha-2 glycoprotein (LRG) remains unclear. We aimed to establish appropriate cutoff values of L...
Capsule endoscopy; Crohn disease; Leucine-rich alpha-2 glycoprotein; Small bowel
1.013
38
Gastroenterology
Medicine
2,024
38,711,912
The early change in pH values after out-of-hospital cardiac arrest is not associated with neurological outcome at hospital discharge.
Resuscitation plus
Resusc Plus
18
null
10.1016/j.resplu.2024.100650
eng
2,024
6
null
2,024
5
1
[BACKGROUND] The association between pH values and outcome for patients after out-of-hospital cardiac arrest (OHCA) was not fully elucidated; besides, the relationship of change in pH values and neurological outcome was unknown. The aim was to explore the association of pH values as well as change in pH values and neur...
Mortality; Neurological outcome; Out-of-hospital cardiac arrest; Post cardiac arrest care; pH value
0.75
20
Emergency Medicine; Emergency Nursing; Cardiology and Cardiovascular Medicine
Medicine; Nursing
2,024
38,711,889
Effective treatment of MET exon 14 skipping mutation-positive non-small cell lung cancer using capmatinib following serious maculopapular rash caused by two MET inhibitors: a case report.
AME case reports
AME Case Rep
8
null
10.21037/acr-23-181
eng
2,024
null
null
2,024
3
14
[BACKGROUND] Multi-gene panel testing and advancements in molecular targeted therapy have improved the overall survival of patients with driver mutation-positive non-small cell lung cancer (NSCLC). Mesenchymal-epithelial transition factor (MET) exon 14 skipping mutation-positive NSCLC, which remains untreated with MET ...
Capmatinib; case report; mesenchymal-epithelial transition factor (MET); non-small cell lung cancer (NSCLC); tepotinib
null
null
null
null
null
38,711,312
Accelerometer-based sedentary time and physical activity from childhood through young adulthood with progressive cardiac changes: a 13-year longitudinal study.
European journal of preventive cardiology
Eur J Prev Cardiol
31
12
10.1093/eurjpc/zwae129
eng
2,024
9
6
null
null
null
[AIMS] Longitudinal evidence on the relationship of sedentary time (ST), light-intensity physical activity (LPA), and moderate-to-vigorous-intensity physical activity (MVPA) with changes in cardiac structure and function in the paediatric population is scarce. This evidence is clinically important due to the impact ST ...
Health guidelines; Health promotion; Hypertension; Left ventricular hypertrophy; Movement behaviour; Obesity; Paediatrics
2.119
130
Cardiology and Cardiovascular Medicine; Epidemiology
Medicine
2,024
38,711,092
Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium.
Journal of intensive care
J Intensive Care
12
1
10.1186/s40560-024-00726-2
eng
2,024
5
6
2,024
5
6
[BACKGROUND] Extracorporeal membrane oxygenation (ECMO) is a rescue therapy in patients with severe acute respiratory distress syndrome (ARDS) secondary to COVID-19. While bleeding and thrombosis complicate ECMO, these events may also occur secondary to COVID-19. Data regarding bleeding and thrombotic events in COVID-1...
Bleeding events; COVID-19; Coagulation disorders; Extracorporeal membrane oxygenation; Thrombotic events
1.286
59
Critical Care and Intensive Care Medicine
Medicine
2,024
38,711,058
Impact of treadmill running on distal femoral cartilage thickness: a cross-sectional study of professional athletes and healthy controls.
BMC sports science, medicine rehabilitation
BMC Sports Sci Med Rehabil
16
1
10.1186/s13102-024-00896-4
eng
2,024
5
6
2,024
5
6
[PURPOSE] This present study aimed to assess the impact of treadmill running on distal femoral cartilage thickness. [METHODS] Professional athletes aged 20 to 40 years with a history of treadmill running (minimum 75 min per week for the past three months or more) and age-, sex-, and body mass index (BMI)-matched health...
Athletes; Cartilage; Exercise; Knee Joint; Running; Ultrasonography
null
null
null
null
null
38,711,031
Harmonization of clinical practice guidelines for primary prevention and screening: actionable recommendations and resources for primary care.
BMC primary care
BMC Prim Care
25
1
10.1186/s12875-024-02388-3
eng
2,024
5
6
2,024
5
6
[BACKGROUND] Clinical practice guidelines (CPGs) synthesize high-quality information to support evidence-based clinical practice. In primary care, numerous CPGs must be integrated to address the needs of patients with multiple risks and conditions. The BETTER program aims to improve prevention and screening for cancer ...
Chronic disease; Clinical practice guidelines; Prevention; Primary care; Screening
1.073
95
Family Practice; Medicine
Medicine
2,024
38,710,462
Enhancing stroke care in Ghana: A systematic review of stroke rehabilitation services.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
33
7
10.1016/j.jstrokecerebrovasdis.2024.107756
eng
2,024
7
null
2,024
5
4
[OBJECTIVE] In Ghana, the shifting demographics of stroke incidence towards young adults have prompted the expansion of stroke care and rehabilitation efforts. Nevertheless, the precise impact of stroke rehabilitation remains unclear. We conducted a systematic review to explore the landscape and effects of stroke rehab...
Ghana; Post-stroke recovery; Rehabilitation; Stroke; Telehealth
0.688
85
Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery
Medicine
2,024
38,710,233
Workflow for the unsupervised clustering of sleep stages identifies light and deep sleep in electrophysiological recordings in mice.
Journal of neuroscience methods
J Neurosci Methods
408
null
10.1016/j.jneumeth.2024.110155
eng
2,024
8
null
2,024
5
6
[BACKGROUND] Sleep physiology plays a critical role in brain development and aging. Accurate sleep staging, which categorizes different sleep states, is fundamental for sleep physiology studies. Traditional methods for sleep staging rely on manual, rule-based scoring techniques, which limit their accuracy and adaptabil...
Deep sleep; EEG; Light sleep; REM sleep; Sleep staging; Unsupervised machine learning
0.726
180
Neuroscience
Neuroscience
2,024
38,710,115
Chitinase 3 like-1 activates the Akt pathway, inducing NF-κB-dependent release of pro-inflammatory cytokines and promoting the proliferative ability in nasopharyngeal carcinoma cells.
Cytokine
Cytokine
179
null
10.1016/j.cyto.2024.156631
eng
2,024
7
null
2,024
5
5
[BACKGROUND] Chitinase 3 like-1 (CHI3L1) has been reported to function as an oncogene in many types of cancer. However, the biological function of CHI3L1 in nasopharyngeal carcinoma (NPC) remains unknown. [METHODS] Differentially expressed genes (DEGs) in NPC tissues in GSE64634 and GSE12452 were downloaded from Gene E...
Akt; Chitinase 3 like-1; Inflammation; Nasopharyngeal carcinoma; Proliferation
1.108
142
Biochemistry; Hematology; Immunology; Immunology and Allergy; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
38,709,742
Comparative analysis of pulmonary ventilation distribution between low-cost and branded incentive spirometers using electrical impedance tomography in healthy adults: Study protocol.
PloS one
PLoS One
19
5
10.1371/journal.pone.0302476
eng
2,024
null
null
2,024
5
6
[BACKGROUND] The Incentive Spirometer (IS) increases lung volume and improves gas exchange by visually stimulating patients to take slow, deep breaths. It prevents respiratory complications and treats postoperative atelectasis in patients undergoing abdominal, thoracic, and neurosurgical procedures. Its effectiveness h...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
38,709,667
Examining mental health and autonomic function as putative mediators of the relationship between sleep and trajectories of cognitive function: findings from the Irish longitudinal study on ageing (TILDA).
Aging mental health
Aging Ment Health
28
12
10.1080/13607863.2024.2345133
eng
2,024
12
null
2,024
5
6
[OBJECTIVES] This study investigates the mediating roles of autonomic function and mental health in the association between sleep and cognitive decline in adults aged 50 and above. [METHOD] A total of 2,697 participants with observations on sleep and mediators at baseline and repeated measures of cognitive function (MM...
Cognitive function; autonomic function; depression; mediation; sleep; stress
null
null
null
null
null
38,709,510
Thick Liquids and Clinical Outcomes in Hospitalized Patients With Alzheimer Disease and Related Dementias and Dysphagia.
JAMA internal medicine
JAMA Intern Med
184
7
10.1001/jamainternmed.2024.0736
eng
2,024
7
1
null
null
null
[IMPORTANCE] Oropharyngeal dysphagia is common in hospitalized patients with Alzheimer disease and related dementias (ADRD). Although the use of thick liquids in patients with dysphagia has been shown to reduce aspiration on direct visualization, there is no clear evidence that this practice translates into improved cl...
null
null
null
null
null
null
38,709,423
Neural digital twins: reconstructing complex medical environments for spatial planning in virtual reality.
International journal of computer assisted radiology and surgery
Int J Comput Assist Radiol Surg
19
7
10.1007/s11548-024-03143-w
eng
2,024
7
null
2,024
5
6
[PURPOSE] Specialized robotic and surgical tools are increasing the complexity of operating rooms (ORs), requiring elaborate preparation especially when techniques or devices are to be used for the first time. Spatial planning can improve efficiency and identify procedural obstacles ahead of time, but real ORs offer li...
Machine learning; Mixed reality; NeRF; Robotic surgery
0.658
71
Biomedical Engineering; Computer Graphics and Computer-Aided Design; Computer Science Applications; Computer Vision and Pattern Recognition; Health Informatics; Medicine; Radiology, Nuclear Medicine and Imaging; Surgery
Computer Science; Engineering; Medicine
2,024
38,709,312
Patient reported outcomes and patient experiences of immune checkpoint modulators for advanced or recurrent melanoma: a mixed methods study.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
32
6
10.1007/s00520-024-08538-8
eng
2,024
5
6
2,024
5
6
[PURPOSE] Little is known about late and long-term patient-reported outcomes (PROs) of immune checkpoint modulators (ICMs) outside clinical trials. We conducted a cross-sectional, mixed-methods study to describe long-term PROs among advanced melanoma patients who began standard of care treatment with ICMs at least 1 ye...
Immune checkpoint modulators; Immunotherapy; Melanoma; Patient-reported outcomes
1.109
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,024
38,709,270
Improvement of skin wound healing by giant salamander skin mucus gel wrapped with bone marrow mesenchymal stem cells via affecting integrin family molecules.
Aging
Aging (Albany NY)
16
9
10.18632/aging.205792
eng
2,024
5
3
2,024
5
3
[BACKGROUND] Traditional bandages, gauze, and cotton balls are increasingly insufficient for addressing complex war injuries characterized by severe bleeding and diverse wound conditions. The giant salamander, a species of high medical value, secretes a unique mucus when stimulated, which has potential applications in ...
bone marrow mesenchymal stem cells; giant salamander skin mucus; integrin; skin; wound healing
1.078
132
Cell Biology; Aging
Biochemistry, Genetics and Molecular Biology
2,024
38,709,230
Clinical and Transcriptional Profiles Reveal the Treatment Effect of Adalimumab in Patients with Initial-Onset and Recurrent Vogt-Koyanagi-Harada Disease.
Ocular immunology and inflammation
Ocul Immunol Inflamm
33
3
10.1080/09273948.2024.2346814
eng
2,025
4
null
2,024
5
6
[PURPOSE] We aimed to evaluate adalimumab efficacy in patients with initial-onset or recurrent Vogt-Koyanagi-Harada (VKH) syndrome. [METHODS] A retrospective clinical study was performed to examine the therapeutic effect of adalimumab in 22 VKH patients,16 with initial-onset and six with recurrent VKH. Another 22 patie...
Adalimumab
0.805
72
Ophthalmology; Immunology and Allergy
Medicine
2,024
38,709,151
Active surveillance is a feasible and safe strategy in selected patients with papillary thyroid cancer and suspicious cervical lymph nodes detected after thyroidectomy.
Archives of endocrinology and metabolism
Arch Endocrinol Metab
68
null
10.20945/2359-4292-2023-0146
eng
2,024
5
6
null
null
null
[OBJECTIVE] After initial treatment, up to 30% of patients with papillary thyroid cancer (PTC) have incomplete response, mainly cervical lymph node (LN) disease. Previous studies have suggested that active surveillance (AS) is a possible option for these patients. Our aim was to report the results of AS in patients wit...
Papillary thyroid carcinoma; active surveillance; locoregional structural disease
0.613
64
Endocrinology, Diabetes and Metabolism
Medicine
2,024
38,708,782
Outcomes of minimal access retroperitoneal para-aortic lymphadenectomy in patients with locally advanced cervical cancer.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
J Obstet Gynaecol
44
1
10.1080/01443615.2024.2344529
eng
2,024
12
null
2,024
5
6
[BACKGROUND] To evaluate outcomes of laparoscopic retroperitoneal para-aortic lymphadenectomy for stage 1b3-3b cervical cancer. [METHODS] Pathology databases searched for all para-aortic lymphadenectomy cases 2005-2016. Descriptive statistics were used to analyse baseline characteristics, cox models for treatment affec...
Cervical cancer; lymphadenectomy
0.459
61
Obstetrics and Gynecology
Medicine
2,024
38,708,643
Use of the FebriDx® host-response point-of-care test may reduce antibiotic use for respiratory tract infections in primary care: a mixed-methods feasibility study.
The Journal of antimicrobial chemotherapy
J Antimicrob Chemother
79
6
10.1093/jac/dkae127
eng
2,024
6
3
null
null
null
[INTRODUCTION] FebriDx® is a CE-marked, single-use point-of-care test with markers for bacterial [C-reactive protein (CRP)] and viral [myxovirus resistance protein A (MxA)] infection, using finger-prick blood samples. Results are available after 10-12 min. We explored the usability and potential impact of FebriDx® in r...
null
1.209
229
Infectious Diseases; Microbiology; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,708,024
Clinical phenotyping in patients with anti-synthetase antibodies using cluster analysis.
Rheumatology advances in practice
Rheumatol Adv Pract
8
2
10.1093/rap/rkae049
eng
2,024
null
null
2,024
4
8
[OBJECTIVES] To characterize clinically distinct subgroups among unselected patients with anti-synthetase antibodies using cluster analysis. [METHODS] This study evaluated patients with anti-synthetase antibodies registered to two independent cohorts; 106 consecutive patients from a prospective, single-centre cohort of...
anti-synthetase syndrome; cluster analysis; interstitial lung disease; myositis; scleroderma
0.715
20
Rheumatology
Medicine
2,024
38,707,847
Individualized Technique Feedback for Instant Technique Improvements and Knee Abduction Moment Reductions - A New Approach for 'Sidestepping' ACL Injuries?
International journal of sports physical therapy
Int J Sports Phys Ther
19
5
10.26603/001c.116274
eng
2,024
null
null
2,024
5
1
[BACKGROUND] Sidestep cutting technique is highly individual and has been shown to influence knee joint loading. However, studies assessing whether individualized technique feedback improves technique and ACL injury-relevant knee joint loads instantly in a sport-specific task are lacking. [PURPOSE] To determine the ins...
biomechanics; injury; knee; prevention; sidestep cutting
0.77
22
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Orthopedics and Sports Medicine
Health Professions; Medicine
2,024
38,707,809
Reclassification of Variants Following Renal Genetics Testing: Uncommon Yet Impactful for Diagnosis and Management.
Kidney international reports
Kidney Int Rep
9
5
10.1016/j.ekir.2024.01.055
eng
2,024
5
null
2,024
2
6
[INTRODUCTION] Genetic testing is increasingly utilized in nephrology practice, but limited real-world data exist on variant reclassification following renal genetics testing. [METHODS] A cohort of patients at the Cleveland Clinic Renal Genetics Clinic who underwent genetic testing through clinical laboratories was ass...
diagnosis and management; kidney disease; renal genetics; variant of uncertain significance; variant reclassification
1.5
61
Nephrology
Medicine
2,024
38,707,771
Comparative Analysis of Clinical and Patient-Reported Outcomes of a New Enhanced Monofocal IOL and a Conventional Monofocal IOL.
Clinical ophthalmology (Auckland, N.Z.)
Clin Ophthalmol
18
null
10.2147/OPTH.S456332
eng
2,024
null
null
2,024
5
1
[PURPOSE] To compare the outcomes of the Tecnis Eyhance ICB00 IOL, designed to enhance intermediate vision, to a conventional Tecnis Monofocal ZCB00 IOL. [METHODS] This retrospective analysis compared two cohorts of patients undergoing lens replacement surgery with bilateral implantation of the Tecnis ICB00 or the Tecn...
Eyhance; enhanced monofocal IOL; patient-reported outcomes
0.936
84
Ophthalmology
Medicine
2,024
38,707,585
Rates of subacromial notching are low following reverse shoulder arthroplasty with a 135° inlay humeral component and a lateralized glenoid.
JSES international
JSES Int
8
3
10.1016/j.jseint.2024.01.009
eng
2,024
5
null
2,024
2
10
[BACKGROUND] Lateralization in reverse shoulder arthroplasty (RSA) decreases bony impingement and improves rotational range of motion, but has been theorized to increase the risk of subacromial notching (SaN). The purpose of this study was to evaluate the presence of SaN following RSA and its relationship with laterali...
Abduction impingement; Inlay; Lateralization; Outcomes; Reverse shoulder arthroplasty; Subacromial notching
0.822
28
Surgery; Orthopedics and Sports Medicine
Medicine
2,024
38,707,421
Epidural dexmedetomidine or esketamine versus fentanyl to decrease ropivacaine use for labor analgesia: A randomized non-inferiority study.
Heliyon
Heliyon
10
9
10.1016/j.heliyon.2024.e30218
eng
2,024
5
15
2,024
4
25
[BACKGROUND] Epidural nonopioid adjuvants also reduce local anesthetic use. We aimed to test the hypothesis that, compared with the present standard fentanyl, the hourly consumption of local anesthetic was at least as good when dexmedetomidine or esketamine was combined with local anesthetic for patient-controlled epid...
Adjuvant; Dexmedetomidine; Epidural; Esketamine; Fentanyl; Labor analgesia; Ropivacaine
0.644
115
Multidisciplinary
Multidisciplinary
2,024
38,707,288
Sex and the veins. A cross-sectional analysis on sexual dysfunction in patients with Chronic Venous Disease.
Heliyon
Heliyon
10
9
10.1016/j.heliyon.2024.e30038
eng
2,024
5
15
2,024
4
24
[BACKGROUND] This study aimed to investigate the presence of sexual dysfunction (SD) in patients with Chronic Venous Disease (CVD) and if CVD treatments may have an impact on SD evolution in these patients. [METHODS] Inclusion criteria were patients of both sexes and genders, with minimum age of 18, with first diagnosi...
ASEX; Chronic venous disease; Quality of life; Sexual dysfunction
0.644
115
Multidisciplinary
Multidisciplinary
2,024
38,706,769
There is a correlation between nutritional status, Self-Rated Health and Life Satisfaction? Evidence from 2018 Health Behaviour in School-aged Children cross sectional study in a sample of Italian adolescents living in Tuscany Region.
Journal of preventive medicine and hygiene
J Prev Med Hyg
65
1
10.15167/2421-4248/jpmh2024.65.1.3178
eng
2,024
3
null
2,024
3
31
[BACKGROUND] Overweight has been associated with several social and phycological problems and is perceived as one of the major health care challenges to focus on in the future. The purpose of the study is to investigate the correlations among nutritional status, assessed by the Body Mass Index, the perception of one's ...
Adolescents; Life Satisfaction; Mental well-being; Obesity; Self-Rated Health
0.629
40
Infectious Diseases; Public Health, Environmental and Occupational Health
Medicine
2,024
38,706,630
Specific Medication Literacy in Older Adults with Asthma.
The journal for nurse practitioners : JNP
J Nurse Pract
20
5
10.1016/j.nurpra.2024.104979
eng
2,024
5
null
2,024
3
27
[PURPOSE] To explore specific medication literacy (SML) of older adults and associations of SML strength. [METHODS] This was an observational study. Participants were at least 60 years old, with an asthma diagnosis and in good health. Data were collected by a registered nurse researcher. The SML data collection instrum...
health literacy; mediation literacy
null
null
null
null
null
38,706,611
Quantitative ultrasound radiomics guided adaptive neoadjuvant chemotherapy in breast cancer: early results from a randomized feasibility study.
Frontiers in oncology
Front Oncol
14
null
10.3389/fonc.2024.1273437
eng
2,024
null
null
2,024
4
19
[BACKGROUND] In patients with locally advanced breast cancer (LABC) receiving neoadjuvant chemotherapy (NAC), quantitative ultrasound (QUS) radiomics can predict final responses early within 4 of 16-18 weeks of treatment. The current study was planned to study the feasibility of a QUS-radiomics model-guided adaptive ch...
adaptive chemotherapy; artificial intelligence; breast cancer; neoadjuvant chemotherapy; quantitative ultrasound (QUS); radiomics
1.075
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,706,279
Fish and Shellfish Consumption, Cognitive Health and Mortality from Alzheimer's Disease among US Adults Aged 60 and Older.
The journal of prevention of Alzheimer's disease
J Prev Alzheimers Dis
11
3
10.14283/jpad.2024.57
eng
2,024
null
null
null
null
null
[BACKGROUND] Relationships of fish-shellfish consumption, cognitive health and mortality from Alzheimer's disease (AD) among US adults aged 60 years and older have not been adequately studied. [OBJECTIVES] To determine the relationship of fish-shellfish consumption, cognitive health and mortality from AD in US adults a...
Older adults; blood mercury level; memory loss; seafood consumption; subjective memory complaints
null
null
null
null
null
38,706,269
"Time Saved" Calculations to Improve Decision-Making in Progressive Disease Studies.
The journal of prevention of Alzheimer's disease
J Prev Alzheimers Dis
11
3
10.14283/jpad.2024.64
eng
2,024
null
null
null
null
null
[BACKGROUND] Disease modifying therapies (DMTs) may be most beneficial in early disease, when progression is slow and changes small, with clinical relevance difficult to interpret. [OBJECTIVES] Time component tests (TCTs) translate differences between treatments from mean change, vertical distance between longitudinal ...
IMM-AD04; disease modifying agents; time saved
null
null
null
null
null
38,706,211
A bacteriophage-based validation of a personal protective equipment doffing procedure to be used with high-consequence pathogens.
Infection control and hospital epidemiology
Infect Control Hosp Epidemiol
45
9
10.1017/ice.2024.84
eng
2,024
5
6
2,024
5
6
[OBJECTIVE] To determine if the high-level personal protective equipment used in the treatment of high-consequence infectious diseases is effective at stopping the spread of pathogens to healthcare personnel (HCP) while doffing. [BACKGROUND] Personal protective equipment (PPE) is fundamental to the safety of HCPs. HCPs...
null
1.048
156
Infectious Diseases; Microbiology; Epidemiology
Medicine
2,024
38,705,948
Stabilizing effect of total ankle arthroplasty by distal translation and lateralization of talus in varus ankle deformity.
Musculoskeletal surgery
Musculoskelet Surg
108
3
10.1007/s12306-024-00820-6
eng
2,024
9
null
2,024
5
5
[BACKGROUND] In end-stage arthritis indicated for total ankle arthroplasty (TAA), full-thickness cartilage damage, subchondral bone defect/shaving, and fluttering of the talar dome occur, shortening the distance between the tibial and talar insertions of ligaments and leading to laxity of ligaments surrounding the ankl...
Deltoid ligament, joint luxation; Stabilizing effect; Total ankle arthroplasty (TAA)
0.67
47
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
38,705,530
Du-moxibustion ameliorates depression-like behavior and neuroinflammation in chronic unpredictable mild stress-induced mice.
Journal of affective disorders
J Affect Disord
358
null
10.1016/j.jad.2024.05.025
eng
2,024
8
1
2,024
5
3
[BACKGROUND] Neuroinflammation is involved in the advancement of depression. Du-moxibustion can treat depression. Here, we explored whether Du-moxibustion could alleviate neuroglia-associated neuro-inflammatory process in chronic unpredictable mild stress (CUMS) mice. [METHODS] C57BL/6J mice were distributed into five ...
Astrocyte; Depression; Du-moxibustion; Microglia
2.121
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
38,704,823
Relationship between uric acid to albumin ratio and saphenous vein graft disease in patients with coronary artery bypass graft.
Coronary artery disease
Coron Artery Dis
35
7
10.1097/MCA.0000000000001378
eng
2,024
11
1
2,024
5
3
[OBJECTIVE] Saphenous vein graft disease (SVGD) remains a challenging issue for patients with coronary artery bypass grafting (CABG). It is associated with poor outcomes and atherosclerosis is the major cause of SVGD. Uric acid to albumin ratio (UAR) is a new marker which associated with cardiovascular mortality. We ai...
null
0.46
70
Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,024
38,704,246
Factors Associated With Pain Catastrophizing in Patients With Chronic Neuropathic Pain: A Cross-Sectional Study.
Pain management nursing : official journal of the American Society of Pain Management Nurses
Pain Manag Nurs
25
4
10.1016/j.pmn.2024.04.004
eng
2,024
8
null
2,024
5
3
[BACKGROUND] Pain catastrophizing is a significant factor in the recovery of patients with chronic pain. This topic has not received the warranted attention in clinical practice, while the outcomes of pain interventions have been suboptimal. This study explores the current situation of pain catastrophizing in patients ...
null
0.639
62
Advanced and Specialized Nursing
Nursing
2,024
38,704,143
Surgical Management of Brain Metastasis from Esophageal Cancer: A Systematic Review and Single-Center Experience.
World neurosurgery
World Neurosurg
187
null
10.1016/j.wneu.2024.04.130
eng
2,024
7
null
2,024
5
3
[BACKGROUND] Brain metastases from esophageal cancer (BMEC) are rare and aggressive, with limited literature on optimal treatment modalities and a standard of care yet to be established. The objective of this study was to systematically review existing literature and perform a retrospective analysis of our institution'...
Brain metastasis; Outcomes; Primary esophageal cancer; Surgical management; Systematic review
0.709
123
Neurology; Surgery
Medicine
2,024