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39,073,897 | Study of feline immunodeficiency virus prevalence and expert opinions on standards of care. | Journal of feline medicine and surgery | J Feline Med Surg | 26 | 7 | 10.1177/1098612X241245046 | eng | 2,024 | 7 | null | null | null | null | [OBJECTIVE] The purpose of this study was to identify knowledge gaps in the global prevalence of feline immunodeficiency virus (FIV) and to obtain professional opinions and experiences regarding FIV in selected countries. We conducted a literature review of abstracts that reported the prevalence of FIV and interviewed ... | FIV; Feline immunodeficiency virus; management; prevalence; retroviruses; review | 0.768 | 81 | Small Animals | Veterinary | 2,024 |
39,073,865 | eHealth-Integrated Psychosocial and Physical Interventions for Chronic Pain in Older Adults: Scoping Review. | Journal of medical Internet research | J Med Internet Res | 26 | null | 10.2196/55366 | eng | 2,024 | 7 | 29 | 2,024 | 7 | 29 | [BACKGROUND] Chronic noncancer pain (CNCP) is highly present among older adults, affecting their physical, psychological, and social functioning. A biopsychosocial multimodal approach to CNCP management is currently extensively suggested by international clinical practice guidelines. Recently, the growing development a... | biopsychosocial model for chronic pain; chronic pain; eHealth; mobile phone; multimodal intervention; older adults; physical intervention; psychological intervention; scoping review; self-management | 1.992 | 214 | Health Informatics | Medicine | 2,024 |
39,073,377 | Identification of severe acute pediatric asthma phenotypes using unsupervised machine learning. | Pediatric pulmonology | Pediatr Pulmonol | 59 | 12 | 10.1002/ppul.27197 | eng | 2,024 | 12 | null | 2,024 | 7 | 29 | [RATIONALE] More targeted management of severe acute pediatric asthma could improve clinical outcomes. [OBJECTIVES] To identify distinct clinical phenotypes of severe acute pediatric asthma using variables obtained in the first 12 h of hospitalization. [METHODS] We conducted a retrospective cohort study in a quaternary... | asthma; informatics; machine learning; pediatrics | 0.79 | 125 | Pediatrics, Perinatology and Child Health; Pulmonary and Respiratory Medicine | Medicine | 2,024 |
39,072,498 | Detection of serum CC16 by a rapid and ultrasensitive magnetic chemiluminescence immunoassay for lung disease diagnosis. | Clinical chemistry and laboratory medicine | Clin Chem Lab Med | 63 | 1 | 10.1515/cclm-2024-0724 | eng | 2,025 | 1 | 29 | 2,024 | 7 | 30 | [OBJECTIVES] It has been reported that serum Clara cell secreted protein 16 (CC16) is a potential biomarker for lung injury diseases, but currently, there is no other method that is faster, more accurate, or more sensitive being applied in clinical practice apart from ELISA. The current study was designed to establishe... | CC16; biomarkers; chemiluminescence; magnetic nanoparticle; monoclonal antibody | 0.952 | 127 | Biochemistry; Medicine; Clinical Biochemistry | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
39,072,180 | Integrated single-cell and bulk RNA sequencing revealed an epigenetic signature predicts prognosis and tumor microenvironment colorectal cancer heterogeneity. | World journal of gastrointestinal oncology | World J Gastrointest Oncol | 16 | 7 | 10.4251/wjgo.v16.i7.3032 | eng | 2,024 | 7 | 15 | null | null | null | [BACKGROUND] Colorectal cancer (CRC) prognosis prediction is currently a major challenge. Epigenetic regulation has been widely reported for its role in cancer development. [AIM] To construct a robust prognostic signature, we used developed and validated across datasets. [METHODS] After constructing the signature, the ... | Colorectal cancer; Epigenetic regulation; Gene expression signature; Micro-environment; Prognosis | null | null | null | null | null |
39,071,532 | Peripheral Coagulation Parameters and Prostate Cancer Association: A Retrospective Study and Mendelian Randomization. | Clinical Medicine Insights. Oncology | Clin Med Insights Oncol | 18 | null | 10.1177/11795549241263950 | eng | 2,024 | null | null | 2,024 | 7 | 26 | [BACKGROUND] The limitations of prostate-specific antigen (PSA) in diagnosing prostate cancer (PCa) necessitate the exploration of novel biomarkers. Recent studies suggest a potential link between coagulation markers, particularly fibrinogen and D-dimer, and PCa. [METHODS] A retrospective single-center analysis on 466 ... | D-dimer; Mendelian randomization; Prostatic neoplasms; biomarker; causality | null | null | null | null | null |
39,071,465 | Rare primary squamous cell carcinoma of the intrahepatic bile duct: A case report and review of literature. | World journal of clinical oncology | World J Clin Oncol | 15 | 7 | 10.5306/wjco.v15.i7.936 | eng | 2,024 | 7 | 24 | null | null | null | [BACKGROUND] Cholangiocarcinoma is the most common malignancy of the biliary tree and has a poor prognosis. Adenocarcinoma is the most common pathological type of cholangiocarcinomas, but rare squamous, adenosquamous, and mucinous variants have been reported without adequate clinical data. [CASE SUMMARY] This report de... | Bile duct; Case report; Cholangiocarcinoma; Clinical characteristics; Squamous cell carcinoma; Treatment | null | null | null | null | null |
39,071,204 | Validation and cross-cultural adaptation of the Arabic version of the Ear Outcome Survey-16 (EOS-16). | Laryngoscope investigative otolaryngology | Laryngoscope Investig Otolaryngol | 9 | 4 | 10.1002/lio2.1304 | eng | 2,024 | 8 | null | 2,024 | 7 | 26 | [BACKGROUND] The Ear Outcome Survey-16 (EOS-16) has been validated according to the health-related quality of life (HRQol) survey guidelines. It has important compatible aspects in evaluating patients with chronic otitis media (COM) suitable for consultation. This study aimed to develop and standardize the Arabic versi... | Arabic; chronic otitis media (COM); otology; translation; validation | 0.641 | 42 | Otorhinolaryngology; Surgery | Medicine | 2,024 |
39,070,876 | Factors Associated with Development of Thigh Compartment Syndrome Following Subtrochanteric and Diaphyseal Femoral Fractures. | The archives of bone and joint surgery | Arch Bone Jt Surg | 12 | 7 | 10.22038/ABJS.2024.74322.3441 | eng | 2,024 | null | null | null | null | null | [OBJECTIVES] Acute compartment syndrome of the thigh (CST) is an ongoing challenge for orthopaedic surgeons as the diagnosis is often difficult to establish. Currently, there is a shortage of studies investigating risk factors for the development of thigh compartment syndrome following subtrochanteric and diaphyseal fe... | Thigh compartment fasciotomy; Thigh compartment syndrome | null | null | null | null | null |
39,070,847 | Effect of continuous nursing on rehabilitation of older patients with joint replacement after discharge. | World journal of clinical cases | World J Clin Cases | 12 | 21 | 10.12998/wjcc.v12.i21.4558 | eng | 2,024 | 7 | 26 | null | null | null | [BACKGROUND] Joint replacement is a common treatment for older patients with high incidences of hip joint diseases. However, postoperative recovery is slow and complications are common, which reduces surgical effectiveness. Therefore, patients require long-term, high-quality, and effective nursing interventions to prom... | Continuous nursing; Discharge; Effect; Joint replacement; Older adults; Rehabilitation | null | 38 | Medicine | Medicine | 2,023 |
39,070,621 | Early vs. Late Anticoagulation in Acute Ischemic Stroke for Non-Atrial Fibrillation Indications. | Research square | Res Sq | null | null | 10.21203/rs.3.rs-4578966/v1 | eng | 2,024 | 7 | 18 | 2,024 | 7 | 18 | [BACKGROUND/OBJECTIVE] In persons whose sole indication for anticoagulation is atrial fibrillation (AF), early therapeutic anticoagulation after acute ischemic stroke (AIS) may decrease ischemic risk without increasing hemorrhagic risk. However, literature to guide anticoagulation timing in patients with a non-AF indic... | anticoagulation; hemorrhagic stroke; ischemic stroke | null | null | null | null | null |
39,070,601 | Comparison of two survey methods for estimating unplanned pregnancy, Bangladesh. | Bulletin of the World Health Organization | Bull World Health Organ | 102 | 8 | 10.2471/BLT.23.290262 | eng | 2,024 | 8 | 1 | 2,024 | 5 | 21 | [OBJECTIVE] To compare the prevalence of unintended pregnancy measured by the Demographic and Health Survey (DHS) and the London Measure of Unplanned Pregnancy in Bangladesh, and explore the extent of discordance between the measures and the factors associated with the discordance. [METHODS] In 2023, we conducted a cro... | null | 1.79 | 201 | Public Health, Environmental and Occupational Health | Medicine | 2,024 |
39,070,225 | A Prospective Study of the Association of IL6 with the Critical Unit and Their Effect on in-Hospital Mortality in Critically Ill Patients. | International journal of general medicine | Int J Gen Med | 17 | null | 10.2147/IJGM.S474250 | eng | 2,024 | null | null | 2,024 | 7 | 24 | [PURPOSE] We previously proposed a new concept, the "critical unit", which covers the structural integrity and function of mitochondria and endothelium. Injury of the critical unit plays a key role in the development of critical illnesses. High levels of inflammation may lead to abnormalities of the critical unit, whic... | IL6; critical unit; critically ill patients; pro-inflammatory response; prognosis | null | null | null | null | null |
39,070,137 | Concurrent Prescription Fills of Opioids and Benzodiazepines Among Postpartum Women During COVID-19. | AJPM focus | AJPM Focus | 3 | 4 | 10.1016/j.focus.2024.100251 | eng | 2,024 | 8 | null | 2,024 | 6 | 11 | [INTRODUCTION] Concurrent prescribing of opioids and benzodiazepines is associated with increased risk of emergency department visits and overdose. Postpartum women commonly receive opioids for pain after delivery and are at risk for postpartum depression/anxiety. Although prior research finds increases in opioid presc... | Benzodiazepines; COVID-19; Concurrent Prescribing; Opioids; Postpartum Women | 1.15 | 6 | Health Informatics; Public Health, Environmental and Occupational Health; Epidemiology | Medicine | 2,024 |
39,070,107 | Evaluation of Higher-Order Aberrations After the Smooth Incision Lenticular Keratomileusis (SILK[TM]) Procedure Using the ELITA[TM] Femtosecond Platform for Correction of Myopic and Astigmatic Refractive Errors. | Clinical ophthalmology (Auckland, N.Z.) | Clin Ophthalmol | 18 | null | 10.2147/OPTH.S466932 | eng | 2,024 | null | null | 2,024 | 7 | 24 | [PURPOSE] To evaluate the changes of higher-order wavefront aberrations following the Smooth Incision Lenticular Keratomileusis (SILK[TM]) procedure for correction of myopic refractive errors with and without astigmatism, using the ELITA[TM] Femtosecond Platform. [METHODS] This prospective study included 24 eyes that u... | corneal refractive surgery; laser-assisted lenticule extraction; smooth incision lenticular keratomileusis; wavefront aberrations | 0.936 | 84 | Ophthalmology | Medicine | 2,024 |
39,070,023 | Role and impact of a specialized cardiometabolic clinic in managing high-risk patients with type 2 diabetes and atherosclerotic cardiovascular disease. | American journal of preventive cardiology | Am J Prev Cardiol | 19 | null | 10.1016/j.ajpc.2024.100706 | eng | 2,024 | 9 | null | 2,024 | 7 | 1 | [BACKGROUND] Lipid-related risk and residual cardiovascular risk remain high in patients with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD). Significant treatment gaps exist in implementation of pluripotent and effective therapies that reduce these risks. [OBJECTIVE] This study evaluates the ... | Atherosclerotic cardiovascular disease; Cardiometabolic clinic; GLP-1 receptor agonist; Lipid-lowering therapy; PCSK9 inhibitor; Residual risk; SGLT2 inhibitor; Type 2 diabetes | 2.001 | 24 | Cardiology and Cardiovascular Medicine | Medicine | 2,024 |
39,069,837 | Remimazolam vs. propofol for general anaesthesia in elderly patients: a meta-analysis with trial sequential analysis. | European journal of anaesthesiology | Eur J Anaesthesiol | 41 | 10 | 10.1097/EJA.0000000000002042 | eng | 2,024 | 10 | 1 | 2,024 | 8 | 12 | [BACKGROUND] Elderly patients comprise an increasing proportion of patients undergoing surgery, and they require special attention due to age-related physiological changes. Propofol is the traditional agent for anaesthesia, and recently, remimazolam, a novel ultra-short-acting benzodiazepine, has emerged as an alternat... | null | 1.25 | 94 | Anesthesiology and Pain Medicine | Medicine | 2,024 |
39,069,670 | Management of Metastatic Spinal Disease - A Practical Approach. | Global spine journal | Global Spine J | null | null | 10.1177/21925682231173646 | eng | 2,024 | 7 | 28 | 2,024 | 7 | 28 | [STUDY DESIGN] Narrative review. [OBJECTIVE] This review presents a comprehensive approach to the management of spinal metastases. [METHODS] N/A. [RESULTS] The wide spectrum of clinical presentation in spinal metastases necessitates a personalized approach to treatment planning. This includes a comprehensive diagnostic... | SBRT; management; multidisciplinary approach; spinal metastases | 1.153 | 59 | Neurology; Orthopedics and Sports Medicine; Surgery | Medicine | 2,024 |
39,069,574 | Evaluation of multiparametric MRI differentiating pleomorphic adenoma from schwannoma in parapharyngeal space. | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery | Eur Arch Otorhinolaryngol | 281 | 11 | 10.1007/s00405-024-08841-4 | eng | 2,024 | 11 | null | 2,024 | 7 | 28 | [PURPOSE] This study aimed to investigate whether multiparametric magnetic resonance imaging (MRI) including dynamic contrast-enhanced (DCE) and diffusion weighted (DW) MRI can differentiate pleomorphic adenoma (PA) from schwannoma in the parapharyngeal space. [METHODS] Forty-six patients with pathologically proven PAs... | Diffusion-weighted MRI; Dynamic contrast-enhanced MRI; Magnetic resonance imaging; Parapharyngeal space; Pleomorphic adenoma; Schwannoma | 0.787 | 94 | Otorhinolaryngology; Medicine | Medicine | 2,024 |
39,069,163 | Kidney function assessment using cystatin C and serum creatinine in heart transplantation recipients: Implications for valganciclovir dosing. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | J Heart Lung Transplant | 43 | 12 | 10.1016/j.healun.2024.07.015 | eng | 2,024 | 12 | null | 2,024 | 7 | 26 | [BACKGROUND] Among heart transplantation (HT) recipients, the accuracy of serum creatinine (sCr)-based estimated glomerular filtration rate (eGFR) may be limited by fluctuations in muscle mass. Cystatin C (cysC) is less influenced by muscle mass, but its levels may increase with obesity and steroid use. Herein, we (1) ... | chronic kidney disease; cystatin C; heart failure; heart transplantation; kidney dysfunction | 2.359 | 162 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery; Transplantation | Medicine | 2,024 |
39,069,016 | The impact of revascularization strategy on clinical failure, hemodynamic failure, and chronic limb-threatening ischemia symptoms in the BEST-CLI Trial. | Journal of vascular surgery | J Vasc Surg | 80 | 6 | 10.1016/j.jvs.2024.07.085 | eng | 2,024 | 12 | null | 2,024 | 7 | 26 | [OBJECTIVE] Sustained clinical and hemodynamic benefit after revascularization for chronic limb-threatening ischemia (CLTI) is needed to resolve symptoms and prevent limb loss. We sought to compare rates of clinical and hemodynamic failure as well as resolution of initial and prevention of recurrent CLTI after endovasc... | Critical limb-threatening ischemia; Endovascular; Hemodynamic; Peripheral artery disease; Revascularization; Surgical bypass; WIfI; Wound healing | 2.075 | 225 | Cardiology and Cardiovascular Medicine; Surgery | Medicine | 2,024 |
39,068,872 | An agent-based method to estimate 3D cell migration trajectories from 2D measurements: Quantifying and comparing T vs CAR-T 3D cell migration. | Computer methods and programs in biomedicine | Comput Methods Programs Biomed | 255 | null | 10.1016/j.cmpb.2024.108331 | eng | 2,024 | 10 | null | 2,024 | 7 | 19 | [BACKGROUND AND OBJECTIVE] Immune cell migration is one of the key features that enable immune cells to find invading pathogens, control tissue damage, and eliminate primary developing tumors. Chimeric antigen receptor (CAR) T-cell therapy is a novel strategy in the battle against various cancers. It has been successfu... | 3D cell migration; Agent-based models; Immunotherapy; Microfluidics-based cell cultures | 1.13 | 150 | Computer Science Applications; Health Informatics; Software | Computer Science; Medicine | 2,024 |
39,068,584 | Effectiveness of Text Messaging in Encouraging Smoking Cessation among Non-Communicable Disease Patients: A Randomized Controlled Trial. | Asian Pacific journal of cancer prevention : APJCP | Asian Pac J Cancer Prev | 25 | 7 | 10.31557/APJCP.2024.25.7.2493 | eng | 2,024 | 7 | 1 | 2,024 | 7 | 1 | [OBJECTIVE] To assess the impact of a text-messaging intervention on smoking cessation among patients with non-communicable diseases. [METHODS] A total of 200 participants were randomly assigned to either a text-messaging intervention group or a control group. The 7-day point prevalence of smoking cessation and exhaled... | non-communicable diseases; smoking cessation; text messaging | 0.53 | 98 | Public Health, Environmental and Occupational Health; Epidemiology; Oncology; Cancer Research | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
39,067,745 | Evaluating complete response rates and predictors in total neoadjuvant therapy for rectal cancer. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract | J Gastrointest Surg | 28 | 10 | 10.1016/j.gassur.2024.07.015 | eng | 2,024 | 10 | null | 2,024 | 7 | 25 | [BACKGROUND] There is a paradigm shift in the management of locally advanced rectal cancer (LARC) from conventional neoadjuvant treatment to total neoadjuvant therapy (TNT). Despite its growing acceptance, there are limited studies that have examined its effects on disease presentation. In addition, it is important to ... | Clinical complete response; Mesorectal facia involvement; Pathologic complete response; Total neoadjuvant therapy; Watch and wait | 0.949 | 149 | Surgery; Gastroenterology | Medicine | 2,024 |
39,067,672 | Functional and anatomical results of subthreshold micropulse laser as rescue treatment for central serous chorioretinopathy after verteporfin shortage. | Photodiagnosis and photodynamic therapy | Photodiagnosis Photodyn Ther | 49 | null | 10.1016/j.pdpdt.2024.104295 | eng | 2,024 | 10 | null | 2,024 | 7 | 25 | [BACKGROUND] To evaluate the anatomical and functional outcomes of high-density subthreshold micropulse laser (HSML) treatment in a cohort of patients diagnosed with chronic central serous chorioretinopathy (CSCR) whose treatment with photodynamic therapy (PDT) was delayed due to the worldwide shortage of verteporfin. ... | Central serous chorioretinopathy; Photodynamic therapy; Rescue therapy; Subthreshold micropulse laser; Verteporfin | 0.724 | 73 | Biophysics; Dermatology; Oncology; Pharmacology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
39,067,319 | Movement disorder phenotype in CTNNB1-syndrome: A complex but recognizable phenomenology. | Parkinsonism related disorders | Parkinsonism Relat Disord | 126 | null | 10.1016/j.parkreldis.2024.107057 | eng | 2,024 | 9 | null | 2,024 | 7 | 9 | [INTRODUCTION] CTNNB1 gene loss-of-function variants cause Neurodevelopmental disorder with spastic diplegia and visual defects (NEDSDV, OMIM 615075). Although motor impairment represents a core feature of this condition, the motor phenotype remains poorly described. We systematically assessed a cohort of 14 patients w... | Bradykinesia; CTNNB1; Dystonia; Movement disorders; Spastic diplegia | null | null | null | null | null |
39,066,593 | The Interactive Effects of The Aerobic Exercise and Vitamin E Supplementation on Parkinson's Rat Model. | Cell journal | Cell J | 26 | 5 | 10.22074/cellj.2024.2023457.1515 | eng | 2,024 | 7 | 13 | 2,024 | 7 | 13 | [OBJECTIVE] In Parkinson's disease (PD), mitochondrial defects and oxidative stress cause an increase in free radicals and the death of dopaminergic neurons in the substantia nigra. By preventing lipid peroxidation and protecting against peroxide radicals, vitamin E is the most important antioxidant of biological membr... | Aerobic exercise; Parkinson's Disease; Stress oxidative; Vitamin E | 0.521 | 43 | Developmental Biology; Molecular Biology; Reproductive Medicine; Cell Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
39,066,545 | International standard of Traditional Chinese Medicine Techniques: Traditional Chinese Medicine guidelines for acute primary headache (2022). | Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan | J Tradit Chin Med | 44 | 4 | 10.19852/j.cnki.jtcm.2024.04.005 | eng | 2,024 | 8 | null | null | null | null | [OBJECTIVE] To summarize the evidence from Traditional Chinese Medicine (TCM) practice in the treatment of acute primary headache and provide clinical practice guidance. [METHODS] The guidelines were developed in accordance with the World Health Organization guideline development manual. After the establishment of stee... | acute primary headache; medicine, Chinese traditional; practice guideline | null | null | null | null | null |
39,066,488 | Depressive Disorder and Trimalleolar Fractures: An Analysis of Outcomes and Costs. | Foot ankle specialist | Foot Ankle Spec | null | null | 10.1177/19386400241267019 | eng | 2,024 | 7 | 26 | 2,024 | 7 | 26 | [INTRODUCTION] Studies have suggested a strong association between depression and poor outcomes following various orthopaedic surgeries. However, depression's impact on complications following open reduction/internal fixation (ORIF) of trimalleolar fractures has not been elucidated. Therefore, this study aimed to deter... | ankle injuries; hospital practice; other; surgical complications; unstable ankle | null | null | null | null | null |
39,063,944 | Novel Approaches for Early Detection of Retinal Diseases Using Artificial Intelligence. | Journal of personalized medicine | J Pers Med | 14 | 7 | 10.3390/jpm14070690 | eng | 2,024 | 6 | 26 | 2,024 | 6 | 26 | [BACKGROUND] An increasing amount of people are globally affected by retinal diseases, such as diabetes, vascular occlusions, maculopathy, alterations of systemic circulation, and metabolic syndrome. [AIM] This review will discuss novel technologies in and potential approaches to the detection and diagnosis of retinal ... | artificial intelligence; deep learning; machine learning; macular edema; maculopathy; retinal imaging; retinopathy | 0.863 | 62 | Medicine | Medicine | 2,024 |
39,063,533 | Successful Elimination of Endemic Rubella in the WHO European Region. Is It Proper to Remove the Recommendation for Preconceptional Immunization? | International journal of environmental research and public health | Int J Environ Res Public Health | 21 | 7 | 10.3390/ijerph21070957 | eng | 2,024 | 7 | 22 | 2,024 | 7 | 22 | [BACKGROUND] Rubella is a contagious viral infection that has garnered significant attention in the field of public health due to its potential consequences, especially during pregnancy. In recent decades, it has been recommended that non-immune women receive immunization during the preconceptional and/or postpartum pe... | IgG; congenital rubella syndrome; preconceptional vaccination; rubella seroprevalence | 0.919 | 229 | Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health | Environmental Science; Medicine | 2,024 |
39,062,686 | Genetic Variants of the Receptor Activator Nuclear of κB Ligand Gene Increase the Risk of Rheumatoid Arthritis in a Mexican Mestizo Population: A Case-Control Study. | Genes | Genes (Basel) | 15 | 7 | 10.3390/genes15070907 | eng | 2,024 | 7 | 11 | 2,024 | 7 | 11 | [UNLABELLED] The Receptor Activator Nuclear of κB Ligand (RANKL) plays an important function in immune responses, activating osteoclast cells and unchanged bone resorption, which in turn leads to bone erosion and inflammation. Genetic variants in the promoter region of the RANKL gene could lead to a higher risk of rheu... | RANK ligand; genetic variant; rheumatoid arthritis | 0.858 | 103 | Genetics; Genetics | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
39,062,282 | Continuous Infusion of Dexmedetomidine for Maintenance of Sedation in an Aggressive Adolescent with Autism Spectrum Disorder in the Emergency Department. | Children (Basel, Switzerland) | Children (Basel) | 11 | 7 | 10.3390/children11070833 | eng | 2,024 | 7 | 9 | 2,024 | 7 | 9 | [BACKGROUND] The treatment of aggressive behavior and agitation in pediatric patients with autism spectrum disorder (ASD) in the emergency department is topical and challenging. [CASE PRESENTATION] We described an adolescent with autism spectrum disorder treated ten times in the pediatric emergency department for sever... | aggressivity; continuous sedation; dexmedetomidine; pediatric emergency department; sedation | 0.674 | 56 | Pediatrics, Perinatology and Child Health | Medicine | 2,024 |
39,062,237 | Factors Predicting In-School and Electronic Bullying among High School Students in the United States: An Analysis of the 2021 Youth Risk Behavior Surveillance System. | Children (Basel, Switzerland) | Children (Basel) | 11 | 7 | 10.3390/children11070788 | eng | 2,024 | 6 | 28 | 2,024 | 6 | 28 | [BACKGROUND] Bullying is a global public health problem with severe adverse effects on behavioral health. Understanding the predictors of victimization by bullying is essential for public policy initiatives to respond to the problem effectively. In addition to traditional in-person bullying, electronic bullying has bec... | bullying; cyberbullying; in-school bully; risk factors; youth | 0.674 | 56 | Pediatrics, Perinatology and Child Health | Medicine | 2,024 |
39,061,464 | Exploring the Acute Effects of Immersive Virtual Reality Biking on Self-Efficacy and Attention of Individuals in the Treatment of Substance Use Disorders: A Feasibility Study. | Brain sciences | Brain Sci | 14 | 7 | 10.3390/brainsci14070724 | eng | 2,024 | 7 | 18 | 2,024 | 7 | 18 | [BACKGROUND] The role of exercise programs during substance use disorder (SUD) treatment is considered particularly supportive in fostering positive psychological and behavioral changes. The treatment of SUD is a challenging and demanding process. Therefore, it is crucial to discover innovative methods to enhance and f... | attention; exercise; self-efficacy; substance use disorders; virtual reality | 0.893 | 78 | Neuroscience | Neuroscience | 2,024 |
39,060,977 | The development of a novel bidirectional fine-tuning mandibular advancement device. | BMC oral health | BMC Oral Health | 24 | 1 | 10.1186/s12903-024-04619-6 | eng | 2,024 | 7 | 26 | 2,024 | 7 | 26 | [OBJECTIVE] To develop a novel mandibular advancement device (MAD) with high comfort, good compliance, and bidirectional fine-tuning capability for patients with obstructive sleep apnea hypopnea syndrome (OSAHS), and to evaluate the therapeutic efficacy of the new MAD. [METHODS] The MAD, featuring upper and lower denta... | Mandibular advancement device; Obstructive sleep apnea hypopnea syndrome; Oral orthodontic appliance; Therapeutic outcomes | 0.843 | 80 | Dentistry | Dentistry | 2,024 |
39,060,947 | Exploring the role of salon professionals in identifying sex trafficking and violence victims in Indiana. | BMC public health | BMC Public Health | 24 | 1 | 10.1186/s12889-024-19467-w | eng | 2,024 | 7 | 26 | 2,024 | 7 | 26 | [BACKGROUND] Sex trafficking victims often have touchpoints with salons for waxing, styling, and other body modification services required by traffickers. Recently, some states have administered laws requiring salon professionals to receive intimate partner violence (IPV)-related training, with even fewer states mandat... | Community-based interventions; Domestic violence; Intimate Partner violence; Salon; Sex trafficking | 1.359 | 211 | Public Health, Environmental and Occupational Health | Medicine | 2,024 |
39,060,490 | Sigmoid volvulus-Can CT features predict outcomes and recurrence? | European radiology | Eur Radiol | 35 | 2 | 10.1007/s00330-024-10979-y | eng | 2,025 | 2 | null | 2,024 | 7 | 25 | [OBJECTIVES] Sigmoid volvulus (SV) is a common cause of bowel obstruction, especially in older patients. SV can be mesenteroaxial (M-SV) or organoaxial (O-SV). The purpose of this study was to assess if CT findings in SV are associated with clinical outcomes. including recurrence, choice of management, and mortality. [... | Colonic distension; Recurrence; Sigmoid volvulus; Volvulus | 1.535 | 182 | Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,024 |
39,060,372 | Targeting tumour surface collage with hydrogel probe: a new strategy to enhance intraoperative imaging sensitivity and stability of bladder cancer. | European journal of nuclear medicine and molecular imaging | Eur J Nucl Med Mol Imaging | 51 | 13 | 10.1007/s00259-024-06848-x | eng | 2,024 | 11 | null | 2,024 | 7 | 26 | [PURPOSE] The incomplete resection of non-muscle invasive bladder cancer (NMIBC) augments the risk of disease recurrence. Imaging-guided surgery by molecular probes represents a pivotal strategy for mitigating postoperative recurrence. Traditional optical molecular probes, primarily composed of antibodies/peptides targ... | Collagen, diagnosis; Endoscopy; Near-infrared imaging; Non-muscle invasive bladder cancer | 2.392 | 192 | Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,024 |
39,060,370 | Safety and tolerability of the protein C activator AB002 in end-stage renal disease patients on hemodialysis: a randomized phase 2 trial. | Communications medicine | Commun Med (Lond) | 4 | 1 | 10.1038/s43856-024-00575-y | eng | 2,024 | 7 | 26 | 2,024 | 7 | 26 | [BACKGROUND] The protein C system regulates blood coagulation, inflammation, and vascular integrity. AB002 is an injectable protein C activating enzyme under investigation to safely prevent and treat thrombosis. In preclinical models, AB002 is antithrombotic, cytoprotective, and anti-inflammatory. Since prophylactic us... | null | 2.098 | 28 | Assessment and Diagnosis; Epidemiology; Internal Medicine; Medicine; Public Health, Environmental and Occupational Health | Medicine; Nursing | 2,024 |
39,060,182 | Wellness in the modulator era: An observational study of the impact of CFTR modulator therapy on the well-being of people with cystic fibrosis. | Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society | J Cyst Fibros | 24 | 4 | 10.1016/j.jcf.2024.06.010 | eng | 2,025 | 7 | null | 2,024 | 7 | 26 | [BACKGROUND] People with cystic fibrosis (PwCF) have experienced substantial improvements in health following use of cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies. However, less is known about how modulator therapies impact well-being. [METHODS] We used a cross-sectional observational s... | CFTR modulator therapy; Cystic fibrosis; Quality of life; Well-being | 1.772 | 98 | Pediatrics, Perinatology and Child Health; Pulmonary and Respiratory Medicine | Medicine | 2,024 |
39,059,321 | Translation and cross-cultural adaptation of the Yale Pharyngeal Residue Severity Rating Scale into Brazilian Portuguese. | Brazilian journal of otorhinolaryngology | Braz J Otorhinolaryngol | 90 | 5 | 10.1016/j.bjorl.2024.101470 | eng | 2,024 | null | null | 2,024 | 7 | 15 | [OBJECTIVE] To report the process of translation and cross-cultural adaptation of theYale Pharyngeal Residue Severity Rating Scale into Brazilian Portuguese. [METHODS] Methodological study approved by the Ethics Committee of the Institution (nº 5.166.256). The English original scale was translated into Brazilian Portug... | Back-translation; Cross-cultural comparison; Deglutition; Endoscopy; Translation | 0.551 | 48 | Otorhinolaryngology | Medicine | 2,024 |
39,058,933 | Picturing Better Materials: Normative Data on a Novel Illustration Set for Scientific and Clinical Use. | American journal of speech-language pathology | Am J Speech Lang Pathol | 33 | 5 | 10.1044/2024_AJSLP-23-00401 | eng | 2,024 | 9 | 18 | 2,024 | 7 | 26 | [PURPOSE] Picture stimuli are essential materials for language research and clinical practice. Here, we generated a modern, full-color set of 310 illustrations representing a carefully designed, culturally sensitive list of imageable nouns. We normed the images in a diverse sample of healthy adults, so the images can b... | null | 0.877 | 93 | Linguistics and Language; Otorhinolaryngology; Speech and Hearing; Developmental and Educational Psychology; Medicine | Health Professions; Medicine; Psychology; Social Sciences | 2,024 |
39,058,803 | Chronic recurrent multifocal osteomyelitis: Case report and review of the literature. | Medicine | Medicine (Baltimore) | 103 | 30 | 10.1097/MD.0000000000038850 | eng | 2,024 | 7 | 26 | null | null | null | [BACKGROUNDS] Chronic recurrent multifocal osteomyelitis (CRMO) is a rare inflammatory disease. [OBJECTIVE] This report aims to analyze the clinical characteristics of CRMO and enhance clinicians' comprehension. We present 3 atypical cases, highlighting their unique clinical features, diagnostic challenges, and effecti... | null | null | null | null | null | null |
39,057,568 | Safety and Preliminary Efficacy of Cervical Paraspinal Interfascial Plane Block for Postoperative Pain after Pediatric Chiari Decompression. | Healthcare (Basel, Switzerland) | Healthcare (Basel) | 12 | 14 | 10.3390/healthcare12141426 | eng | 2,024 | 7 | 17 | 2,024 | 7 | 17 | [BACKGROUND] Surgery for lesions of the posterior fossa is associated with significant postoperative pain in pediatric patients related to extensive manipulation of the suboccipital musculature and bone. In this study, we assess the preliminary safety, effect on neuromonitoring, and analgesic efficacy of applying a cer... | Chiari type I malformation; cervical cervicis plane (CCeP) block; intraoperative neuromonitoring; pediatric regional anesthesia; suboccipital decompression | 0.83 | 33 | Health Policy | Medicine | 2,024 |
39,057,554 | Effectiveness of Harm Reduction Interventions in Chemsex: A Systematic Review. | Healthcare (Basel, Switzerland) | Healthcare (Basel) | 12 | 14 | 10.3390/healthcare12141411 | eng | 2,024 | 7 | 15 | 2,024 | 7 | 15 | [UNLABELLED] The phenomenon of chemsex has emerged as an essential public health issue in recent years. This systematic review aimed to investigate currently available harm reduction strategies and to evaluate the efficacy of the corresponding interventions. [METHODS] A systematic review of the scientific literature re... | chemsex; harm reduction; health promotion; risk behavior; systematic review | 0.83 | 33 | Health Policy | Medicine | 2,024 |
39,056,763 | Upregulation of Transferrin Receptor 1 (TfR1) but Not Glucose Transporter 1 (GLUT1) or CD98hc at the Blood-Brain Barrier in Response to Valproic Acid. | Cells | Cells | 13 | 14 | 10.3390/cells13141181 | eng | 2,024 | 7 | 11 | 2,024 | 7 | 11 | [BACKGROUND] Transferrin receptor 1 (TfR1), glucose transporter 1 (GLUT1), and CD98hc are candidates for targeted therapy at the blood-brain barrier (BBB). Our objective was to challenge the expression of TfR1, GLUT1, and CD98hc in brain capillaries using the histone deacetylase inhibitor (HDACi) valproic acid (VPA). [... | CD98hc; ICP-MS; capillary depletion; cell culture; glucose transporter 1; nanoparticle; transferrin receptor; valproic acid | 1.67 | 158 | Biochemistry, Genetics and Molecular Biology | Biochemistry, Genetics and Molecular Biology | 2,024 |
39,056,248 | Line-field confocal optical coherence tomography for the differential diagnosis of porokeratosis from clinical mimickers: a preliminary study. | Clinical and experimental dermatology | Clin Exp Dermatol | 49 | 12 | 10.1093/ced/llae285 | eng | 2,024 | 11 | 22 | null | null | null | [BACKGROUND] Porokeratosis variants are relatively rare and can be clinically misdiagnosed with several common papulokeratotic mimickers. Line-field confocal optical coherence tomography (LC-OCT) is a new technology able to explore the skin in vivo up to a depth of 500 µm. [OBJECTIVES] To investigate the role of LC-OCT... | null | 0.692 | 92 | Dermatology | Medicine | 2,024 |
39,056,135 | Objective assessment of tear film in blepharospasm, facial hemispam and aberrant regeneration with periocular botulinum toxin-A. | European journal of ophthalmology | Eur J Ophthalmol | 35 | 2 | 10.1177/11206721241266008 | eng | 2,025 | 3 | null | 2,024 | 7 | 26 | [PURPOSE] Study the effect on the tear film in blepharospasm (BEB), facial hemispasm (FH), or aberrant regeneration (AR) treated with Botulinum Toxin (BTX-A). [METHODS] A prospective study was used to evaluate the tear film in patients with BEB, FH, or AR treated with BTX-A. Schirmer tests, break-up time (BUT), optical... | OCT; blepharospasm; facial hemispasm; or aberrant regeneration; periocular botulinum toxin; tear meniscus | 0.647 | 69 | Medicine; Ophthalmology | Medicine | 2,024 |
39,055,736 | Serological responses and clinical outcomes following a three-dose primary COVID-19 vaccine schedule in kidney transplant recipients and people on dialysis. | Clinical translational immunology | Clin Transl Immunology | 13 | 7 | 10.1002/cti2.1523 | eng | 2,024 | null | null | 2,024 | 7 | 25 | [OBJECTIVES] Despite vaccination strategies, people with chronic kidney disease, particularly kidney transplant recipients (KTRs), remained at high risk of poor COVID-19 outcomes. We assessed serological responses to the three-dose COVID-19 vaccine schedule in KTRs and people on dialysis, as well as seroresponse predic... | antibody response; dialysis; immune response; kidney transplant | null | null | null | null | null |
39,054,979 | Homicidal or suicidal death? Evidence-based approach to assessing cause of death in a peculiar forensic case. | La Clinica terapeutica | Clin Ter | 175 | Suppl 1(4) | 10.7417/CT.2024.5082 | eng | 2,024 | null | null | null | null | null | [BACKGROUND] In recent years, the improvement of common standards of forensic practice has received attention to promote an unambiguous and better-quality forensic investigation method. Although most hanging deaths are attributed to suicides, cases occasionally occur due to accidents or homicides. From an investigative... | BPA; Complex suicides; Forensic Pathology; Hanging; Multidisciplinary approach; Stab wounds | null | null | null | null | null |
39,054,682 | Visual-Motor Integration (VMI) Is Also Relevant for Computer, Smartphone, and Tablet Use by Adults: Introducing the Brief Box Clicking Test. | The American journal of occupational therapy : official publication of the American Occupational Therapy Association | Am J Occup Ther | 78 | 5 | 10.5014/ajot.2024.050680 | eng | 2,024 | 9 | 1 | null | null | null | [IMPORTANCE] Visual-motor integration (VMI) is typically examined in children to promote handwriting, but it may also be relevant for adults' capacity for technology use. [OBJECTIVE] To examine the reliability and validity of speed of completion of the box clicking test, a web-based test of VMI. [DESIGN] Participants i... | null | null | null | null | null | null |
39,054,677 | Splenic complications in pediatric sickle cell disease: A retrospective cohort review. | Pediatric blood cancer | Pediatr Blood Cancer | 71 | 10 | 10.1002/pbc.31219 | eng | 2,024 | 10 | null | 2,024 | 7 | 25 | [OBJECTIVE] To delineate the natural history of splenic complications other than loss of splenic function in children with sickle cell disease (SCD), we performed a retrospective chart review of patients with SCD treated at the Texas Children's Hospital. [METHODS] We determined the dates of diagnoses of splenic complic... | acute splenic sequestration crises; hydroxyurea; hypersplenism; sickle cell disease; splenectomy; splenomegaly | null | null | null | null | null |
39,054,558 | Elevated neutrophil extracellular traps in systemic sclerosis-associated vasculopathy and suppression by a synthetic prostacyclin analog. | Arthritis research therapy | Arthritis Res Ther | 26 | 1 | 10.1186/s13075-024-03379-6 | eng | 2,024 | 7 | 25 | 2,024 | 7 | 25 | [OBJECTIVES] Neutrophils and neutrophil extracellular traps (NETs) contribute to the vascular complications of multiple diseases, but their role in systemic sclerosis (SSc) is understudied. We sought to test the hypothesis that NETs are implicated in SSc vasculopathy and that treatment with prostacyclin analogs may ame... | Neutrophil extracellular traps (NETs); Prostacyclin; Systemic sclerosis; Vascular complications | null | null | null | null | null |
39,054,491 | Pembrolizumab plus either epacadostat or placebo for cisplatin-ineligible urothelial carcinoma: results from the ECHO-307/KEYNOTE-672 study. | BMC cancer | BMC Cancer | 23 | Suppl 1 | 10.1186/s12885-023-10727-3 | eng | 2,024 | 7 | 25 | 2,024 | 7 | 25 | [BACKGROUND] Indoleamine 2,3- dioxygenase 1 (IDO1) is an immunosuppressive enzyme that has been correlated with shorter disease-specific survival in patients with urothelial carcinoma (UC). IDO1 may counteract the antitumor effects of immune checkpoint inhibitors. Epacadostat is a potent and highly selective inhibitor ... | Epacadostat; IDO1; Immune checkpoint inhibition; Immunotherapy; PD-L1; PD1; Pembrolizumab; Randomized controlled study; Urinary tract neoplasms; Urothelial carcinoma | 1.178 | 171 | Cancer Research; Genetics; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
39,054,237 | Racial, Ethnic, and Age-Related Disparities in Sedation and Restraint Use for Older Adults in the Emergency Department. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | Am J Geriatr Psychiatry | 33 | 1 | 10.1016/j.jagp.2024.07.004 | eng | 2,025 | 1 | null | 2,024 | 7 | 8 | [OBJECTIVES] Older adults may present to the emergency department (ED) with agitation, a symptom often resulting in chemical sedation and physical restraint use which carry significant risks and side effects for the geriatric population. To date, limited literature describes the patterns of differential restraint use i... | agitation; chemical sedation; emergency department; geriatric psychiatry; health disparities; physical restraint | 1.378 | 150 | Geriatrics and Gerontology; Psychiatry and Mental Health | Medicine | 2,024 |
39,054,231 | Reducing candidaemia risk in urology patients: Revised algorithm Pharmacist-Led Implementation. | Infection, disease health | Infect Dis Health | 29 | 4 | 10.1016/j.idh.2024.06.001 | eng | 2,024 | 11 | null | 2,024 | 7 | 25 | [BACKGROUND] Candidaemia is an invasive infection with high morbidity and mortality. All urology procedures carry risk of post-operative infection. Risk mitigation strategies include preoperative urine culture and treatment of cultured organism(s) regardless of symptoms. After zero cases of candidaemia for two years, t... | Antimicrobial stewardship; Indwelling catheter; Pharmacist; Pre-operative; Ureteric stent; Urology | null | null | null | null | null |
39,054,206 | The relationship between Foot Posture Index and plantar pressure in a community-dwelling adult population with Type 2 diabetes. | Journal of tissue viability | J Tissue Viability | 33 | 4 | 10.1016/j.jtv.2024.07.013 | eng | 2,024 | 11 | null | 2,024 | 7 | 22 | [AIMS] To investigate the contribution of foot type to plantar pressures in a community-dwelling adult population with type 2 diabetes. [METHODS] Foot Posture Index-6 (FPI-6) as a measure of foot type, barefoot plantar pressure (peak pressures and pressure-time integrals), presence of forefoot deformities, peripheral n... | Diabetes; Foot posture index; Plantar pressure; Pressure-time integral | 0.655 | 45 | Dermatology; Pathology and Forensic Medicine | Medicine | 2,024 |
39,053,650 | Long-term outcomes of EUS-guided balloon-occluded gastrojejunostomy bypass for malignant gastric outlet obstruction (with video). | Gastrointestinal endoscopy | Gastrointest Endosc | 101 | 1 | 10.1016/j.gie.2024.07.006 | eng | 2,025 | 1 | null | 2,024 | 7 | 23 | [BACKGROUND AND AIMS] EUS-guided gastroenterostomy (EUS-GE) is a minimally invasive technique for gastric outlet obstruction (GOO). EUS-guided balloon-occluded gastrojejunostomy bypass (EPASS) aims to improve stent deployment and minimize migration in EUS-GE. In this study, we evaluated the long-term outcomes of EPASS.... | null | 2.018 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,024 |
39,053,608 | Socioeconomic Inequalities in Intakes of Ultraprocessed and Minimally Processed Foods in Nationally Representative Samples of Adults in Canada: An Analysis of Trends between 2004 and 2015. | The Journal of nutrition | J Nutr | 154 | 10 | 10.1016/j.tjnut.2024.07.029 | eng | 2,024 | 10 | null | 2,024 | 7 | 23 | [BACKGROUND] Individuals with a lower socioeconomic position (SEP) often have higher intakes of ultraprocessed food (UPF) and lower intakes of minimally processed food (MPF); however, studies have not examined trends in absolute and relative gaps and gradients in UPF and MPF intake using multiple indicators of SEP. [OB... | adults; dietary inequalities; socioeconomic position; ultraprocessed foods; unprocessed or minimally processed foods | 1.152 | 306 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,024 |
39,053,589 | Efficacy of Thyroid Hormone Replacement Therapy in Nasopharyngeal Carcinoma Patients with Radiation-Induced Subclinical Hypothyroidism. | Experimental and clinical endocrinology diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association | Exp Clin Endocrinol Diabetes | 132 | 11 | 10.1055/a-2373-0030 | eng | 2,024 | 11 | null | 2,024 | 7 | 25 | [AIMS] Hypothyroidism is a common side effect of radiotherapy for nasopharyngeal carcinoma. However, the impact of thyroid hormone replacement therapy on patients with radiation-induced subclinical hypothyroidism has not been extensively explored. This study aimed to analyze the efficacy of thyroid hormone replacement ... | null | null | null | null | null | null |
39,053,520 | Evaluating the impact of short-term nitrate-rich dietary supplementation on endothelial function in COPD: A randomized crossover study. | Respiratory medicine | Respir Med | 232 | null | 10.1016/j.rmed.2024.107745 | eng | 2,024 | 10 | null | 2,024 | 7 | 24 | [AIM] This study aimed to investigate the acute effects of dietary nitrate ingestion through l-arginine supplementation or dehydrated beet consumption on endothelial function in chronic obstructive pulmonary disease (COPD) patients. The secondary outcome was to analyze arterial stiffness, plasma nitrate, and nitrate/pr... | COPD; Dietary nitrates; Endothelium; Endothelium dysfunction; Flow-mediated dilation | 1.063 | 145 | Pulmonary and Respiratory Medicine | Medicine | 2,024 |
39,053,250 | 3,4,5-tri-O-caffeoylquinic acid attenuates influenza A virus induced inflammation through Toll-like receptor 3/7 activated signaling pathway. | Phytomedicine : international journal of phytotherapy and phytopharmacology | Phytomedicine | 132 | null | 10.1016/j.phymed.2024.155896 | eng | 2,024 | 9 | null | 2,024 | 7 | 20 | [BACKGROUND] 3,4,5-tri-O-caffeoylquinic acid (3,4,5-TCQA), a natural polyphenolic acid, has been shown to be effective against influenza A virus (IAV) infection. Although it was found to inhibit the neuraminidase of IAV, it may also perturb other cellular functions, as polyphenolic acids have shown antioxidant, anti-in... | 3,4,5-TCQA; Anti-inflammation; Anti-influenza; TLR3/7 | 1.694 | 150 | Complementary and Alternative Medicine; Drug Discovery; Molecular Medicine; Pharmaceutical Science; Pharmacology | Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,024 |
39,053,020 | Predicting cachexia in hepatocellular carcinoma patients: a nomogram based on MRI features and body composition. | Acta radiologica (Stockholm, Sweden : 1987) | Acta Radiol | 65 | 8 | 10.1177/02841851241261703 | eng | 2,024 | 8 | null | 2,024 | 7 | 25 | [BACKGROUND] Approximately half of all patients with hepatocellular carcinoma (HCC) develop cachexia during the course of the disease. It is important to be able to predict which patients will develop cachexia at an early stage. [PURPOSE] To develop and validate a nomogram based on the magnetic resonance imaging (MRI) ... | Cachexia; body composition; hepatocellular carcinoma; imaging feature; magnetic resonance imaging | 0.412 | 82 | Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,024 |
39,052,759 | Accuracy of 4 Different Methods for Estimation of Remaining Growth and Timing of Epiphysiodesis. | The Journal of bone and joint surgery. American volume | J Bone Joint Surg Am | 106 | 20 | 10.2106/JBJS.23.01483 | eng | 2,024 | 10 | 16 | 2,024 | 7 | 25 | [BACKGROUND] The calculation of remaining growth in children and the timing of epiphysiodesis in those with leg-length discrepancy (LLD) is most often done with 4 methods: the Green-Anderson, White-Menelaus, Moseley straight-line graph, and multiplier methods. The aims of this study were to identify the most accurate m... | null | null | null | null | null | null |
39,051,761 | High-resolution melting analysis to authenticate deer-derived materials in processed products in China using a cytochrome oxidase I mini-barcode. | Journal of the science of food and agriculture | J Sci Food Agric | 104 | 15 | 10.1002/jsfa.13761 | eng | 2,024 | 12 | null | 2,024 | 7 | 25 | [BACKGROUND] Deer-derived materials (antler, venison, fetus, penis, bone, tail, and others) are some of the most valuable traditional animal-based medicinal and food materials in China. In production, processing, and trade, the quality of deer products varies. The market is confusing, and counterfeit and shoddy product... | cytochrome oxidase I; high resolution melting; sequencing | null | null | null | null | null |
39,051,759 | Safety and feasibility of transcranial direct current stimulation in end-stage renal disease patients undergoing hemodialysis: an exploratory study. | Jornal brasileiro de nefrologia | J Bras Nefrol | 46 | 4 | 10.1590/2175-8239-JBN-2024-0010en | eng | 2,024 | null | null | 2,024 | 7 | 19 | [INTRODUCTION] Patients with end-stage renal disease often face a challenging routine of hemodialysis, dietary restrictions, and multiple medications, which can affect their hemodynamic function. Home-based, safe, and nonpharmacological approaches such as transcranial direct current stimulation (tDCS) should be combine... | null | null | null | null | null | null |
39,051,612 | Lower urinary tract symptoms in elderly men: Considerations for prostate cancer testing. | The Prostate | Prostate | 84 | 14 | 10.1002/pros.24772 | eng | 2,024 | 10 | null | 2,024 | 7 | 25 | [PURPOSE] Both lower urinary tract symptoms (LUTS) and prostate cancer (PCa) are common in elderly men. While LUTS are generally due to a benign etiology, they may provoke an evaluation with prostate-specific antigen (PSA), which can lead to a cascade of further testing and possible overdiagnosis in patients with compe... | lower urinary tract symptoms; prostate cancer; prostatic neoplasms | 1.071 | 138 | Urology; Oncology | Medicine | 2,024 |
39,051,252 | Can We Steer Nursing Home Residents Away from Loneliness? A Qualitative Study of Cycling without Age. | Geriatrics (Basel, Switzerland) | Geriatrics (Basel) | 9 | 4 | 10.3390/geriatrics9040088 | eng | 2,024 | 6 | 25 | 2,024 | 6 | 25 | [BACKGROUND] Loneliness among nursing home residents is an increasing public health issue and consists of a combination of social, emotional, and existential loneliness. Cycling Without Age (CWA) involves taking nursing home residents on trishaw rides pedaled by trained volunteer 'pilots'. This study aims to explore nu... | Cycling Without Age; bicycling; loneliness; mental health; nursing home; qualitative methods | 0.233 | 43 | Geriatrics and Gerontology | Medicine | 2,012 |
39,051,189 | Physically Active Lifestyle Attenuates Impairments on Lung Function and Mechanics in Hypertensive Older Adults. | Advances in respiratory medicine | Adv Respir Med | 92 | 4 | 10.3390/arm92040027 | eng | 2,024 | 7 | 22 | 2,024 | 7 | 22 | [AIM] Physical activity attenuates hypertension in older adults, but its impact on pulmonary function and mechanics in hypertensive older adults is unknown. The study seeks to understand whether a physically active lifestyle can improve respiratory capacity, the mechanical efficiency of the lungs, and, consequently, th... | healthy lungs; hypertension; physical exercise; respiratory system | null | null | null | null | null |
39,051,154 | Telehealth Uptake Among Hispanic People During COVID-19: Retrospective Observational Study. | JMIR medical informatics | JMIR Med Inform | 12 | null | 10.2196/57717 | eng | 2,024 | 7 | 24 | 2,024 | 7 | 24 | [BACKGROUND] The Hispanic community represents a sizeable community that experiences inequities in the US health care system. As the system has moved toward digital health platforms, evaluating the potential impact on Hispanic communities is critical. [OBJECTIVE] The study aimed to investigate demographic, socioeconomi... | Hispanic; Hispanics; ICT; Spanish; access; accessibility; demographic; demographics; digital divide; e-health; eHealth; equity; health access; health equity; inequities; inequity; information and communication technology; observational; socioeconomic; socioeconomics; telehealth; telemedicine; usage; utilization | 1.007 | 55 | Health Information Management; Health Informatics | Health Professions; Medicine | 2,024 |
39,050,876 | Fe3O4 Nanoparticles That Modulate the Polarisation of Tumor-Associated Macrophages Synergize with Photothermal Therapy and Immunotherapy (PD-1/PD-L1 Inhibitors) to Enhance Anti-Tumor Therapy. | International journal of nanomedicine | Int J Nanomedicine | 19 | null | 10.2147/IJN.S459400 | eng | 2,024 | null | null | 2,024 | 7 | 17 | [INTRODUCTION] Traditional surgical resection, radiotherapy, and chemotherapy have been the treatment options for patients with head and neck squamous cell carcinoma (HNSCC) over the past few decades. Nevertheless, the five-year survival rate for patients has remained essentially unchanged, and research into treatments... | head and neck squamous cell carcinoma; immunotherapy; photothermal therapy; tumor-associated macrophages | 1.306 | 193 | Bioengineering; Biomaterials; Biophysics; Drug Discovery; Medicine; Nanoscience and Nanotechnology; Organic Chemistry; Pharmaceutical Science | Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,024 |
39,050,865 | Risk factors of peritoneal dialysis-related peritonitis in the Japan Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS). | Clinical kidney journal | Clin Kidney J | 17 | 7 | 10.1093/ckj/sfae202 | eng | 2,024 | 7 | null | 2,024 | 7 | 1 | [BACKGROUND] Peritoneal dialysis (PD)-related peritonitis is a major complication of PD. Wide variations in peritonitis prevention, treatment strategies and consequences are seen between countries. These between-country differences may result from modifiable risk factors and clinical practices. [METHODS] A total of 122... | PDOPPS; antibiotic prophylaxis; peritoneal dialysis; peritonitis; risk factor | 1.393 | 69 | Nephrology; Transplantation | Medicine | 2,024 |
39,050,614 | Physical activity and recreational screen time among Chinese children and adolescents: a national cross-sectional study. | Frontiers in public health | Front Public Health | 12 | null | 10.3389/fpubh.2024.1376330 | eng | 2,024 | null | null | 2,024 | 7 | 10 | [BACKGROUND] The increasing prevalence of physical inactivity and prolonged Recreational Screen Time (RST) among children and adolescents is emerging as a significant public health concern. This study investigates the current status of Physical Activity (PA) and RST among Chinese children and adolescents from 2017 to 2... | Chinese; children and adolescents; cross-sectional study; physical activity; recreational screen time | 1.027 | 119 | Public Health, Environmental and Occupational Health | Medicine | 2,024 |
39,050,517 | A Systematic Review of the Effect of Physical Rehabilitation on Balance in People with Diabetic Peripheral Neuropathy Who are at Risk of Falling. | Clinical interventions in aging | Clin Interv Aging | 19 | null | 10.2147/CIA.S459492 | eng | 2,024 | null | null | 2,024 | 7 | 19 | [BACKGROUND] Falls are a significant issue in people with diabetic peripheral neuropathy. Balance interventions have been broadly administered in individuals with diabetic peripheral neuropathy, but the effects on static and dynamic balance in those who are at risk of falling have not yet been comprehensively reviewed.... | balance; diabetic peripheral neuropathy; fall risk; physical rehabilitation exercise interventions; rehabilitation | 1.117 | 114 | Medicine; Geriatrics and Gerontology | Medicine | 2,024 |
39,050,291 | A Process Evaluation of a Mobile App for Medical Students Aimed at Increasing Resilience and Decreasing Stigma in Mental Health. | Cureus | Cureus | 16 | 6 | 10.7759/cureus.63054 | eng | 2,024 | 6 | null | 2,024 | 6 | 24 | [OBJECTIVE] The purpose of this pilot study was to conduct a process evaluation of a mental health and wellness mobile health (mHealth) application for medical students designed to increase resilience and decrease mental health stigma. [METHODS] The customized application, MindfulMEDS, was developed with peer-focused i... | behavioral health; medical students; mental health; mental health apps; mobile health; psychiatry and mental health; suicide prevention | null | null | null | null | null |
39,050,003 | Is gut microbiota of patients with ALS different from that of healthy individuals? | Turkish journal of medical sciences | Turk J Med Sci | 54 | 3 | 10.55730/1300-0144.5825 | eng | 2,024 | null | null | 2,024 | 5 | 7 | [BACKGROUND/AIM] Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Several studies have shown that alterations of microbiota increase the risk of neurodegenerative disorders. We aimed to reveal whether there is a difference in the gut microbiota of patients with ALS. [MATERIALS AND METHODS] The ... | ALS; Amyotrophic lateral sclerosis; gut microbiota; neurodegenerative diseases; pathogenesis of ALS | 0.386 | 44 | Medicine | Medicine | 2,024 |
39,049,842 | Validation of the Chinese version of the adverse life experiences scale. | Frontiers in pediatrics | Front Pediatr | 12 | null | 10.3389/fped.2024.1403183 | eng | 2,024 | null | null | 2,024 | 7 | 10 | [BACKGROUND] Adverse childhood experiences (ACEs) are strongly linked to many mental health problems, and play important role in the intergenerational transmission of psychopathology. Additionally, the developmental timing may also be critical in ACEs' impact on these problems. The Adverse Life Experiences Scale (ALES)... | adverse childhood experiences; assessment; developmental timing; intergenerational transmission; mental health problem | 0.738 | 83 | Pediatrics, Perinatology and Child Health | Medicine | 2,024 |
39,049,702 | Association of body mass index with muscle strength and cardiorespiratory fitness: A cross-sectional study based on Chinese adolescents. | American journal of human biology : the official journal of the Human Biology Council | Am J Hum Biol | 36 | 10 | 10.1002/ajhb.24118 | eng | 2,024 | 10 | null | 2,024 | 7 | 25 | [BACKGROUND] Muscle strength and cardiorespiratory fitness are important components of physical fitness and are important for the physical and mental health development of university students. However, obesity is also an important factor affecting physical fitness, and there are few studies on how body mass index (BMI)... | null | 0.676 | 97 | Anatomy; Anthropology; Ecology, Evolution, Behavior and Systematics; Genetics | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Social Sciences | 2,024 |
39,049,630 | Heterogeneity of Wnt1-Cre-marked and Pax2-Cre-marked first branchial arch cranial neural crest cells in mice. | Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology | Hua Xi Kou Qiang Yi Xue Za Zhi | 42 | 4 | 10.7518/hxkq.2024.2023374 | eng | 2,024 | 8 | 1 | null | null | null | [OBJECTIVES] This study aimed to explore the heterogeneity and gene ontology of Wnt1-Cre-marked and Pax2-Cre-marked first branchial arch cranial neural crest cells (CNCs) in mice. [METHODS] The embryos of Wnt1-Cre;R26R[mTmG] and Pax2-Cre;R26R[mTmG] at embryonic day (E)8.0-E9.25 were collected for histological observati... | Pax2-Cre; Wnt1-Cre; cranial neural crest cells; first branchial arch; single-cell RNA sequencing | null | null | null | null | null |
39,049,558 | Modeling impact of inflation reduction act price negotiations on new drug pipeline considering differential contributions of large and small biopharmaceutical companies. | Clinical trials (London, England) | Clin Trials | 22 | 1 | 10.1177/17407745241259112 | eng | 2,025 | 2 | null | 2,024 | 7 | 24 | [BACKGROUND/AIMS] Provisions of the Inflation Reduction Act mandating drug price negotiation by the Centers for Medicare Medicaid Services have been criticized as a threat to pharmaceutical innovation. This study models potential impacts of the Inflation Reduction Act on drug approvals based on the differential contri... | Inflation Reduction Act; biopharmaceutical; clinical trials; drug approvals; drug prices; finance; pharmaceutical innovation; public policy; research and development; revenue | 1.189 | 79 | Medicine; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,024 |
39,049,489 | Retrograde coronary venous ethanol ablation for ventricular tachycardia in a patient with inaccessible substrate due to previous surgery. | Journal of cardiovascular electrophysiology | J Cardiovasc Electrophysiol | 35 | 9 | 10.1111/jce.16380 | eng | 2,024 | 9 | null | 2,024 | 7 | 24 | [INTRODUCTION] Catheter-based radiofrequency (RF) ablation is generally regarded as the standard approach for patients with ventricular tachycardia (VT) refractory to antiarrhythmic drug therapy and may be considered as a first-line approach when there is a preference to avoid these agents. Patients with a history of c... | cardiac surgery; ethanol ablation; ventricular tachycardia | 1.187 | 154 | Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,024 |
39,049,467 | Tricortical versus bicortical anchorage in a double-screw tandem skeletal expander and a single-screw maxillary anchorage rapid palatal expander: A finite element analysis. | Korean journal of orthodontics | Korean J Orthod | null | null | 10.4041/kjod23.270 | eng | 2,024 | 7 | 25 | 2,024 | 7 | 25 | [OBJECTIVE] This study aims to employ finite element method (FEM) analysis to compare the differences between bicortical and tricortical anchorage of the posterior miniscrews in a single-screw miniscrew-assisted rapid palatal expansion (MARPE) and a double-screw tandem skeletal expander (TSE) under open and closed sutu... | Bicortical anchorage; Miniscrew anchorage; Tandem skeletal expander; Tricortical anchorage | 0.809 | 37 | Orthodontics | Dentistry | 2,024 |
39,049,282 | Graph Theory to Map Nursing Knowledge of Diagnosis and Interventions in Women's Health. | Studies in health technology and informatics | Stud Health Technol Inform | 315 | null | 10.3233/SHTI240168 | eng | 2,024 | 7 | 24 | null | null | null | [OBJECTIVE] Apply Graph Theory to analyze and map knowledge about nursing diagnoses and interventions, based on records of consultations carried out by nurses, in women's health, in primary health care. [METHODS] Secondary data from a cross-sectional study were used. Records of nursing consultations carried out during ... | Graph Theory; Nursing Process; Primary Health Care; Standardized Nursing Terminology | null | null | null | null | null |
39,049,078 | What works in implementing shared medical appointments for patients with diabetes in primary care to enhance reach: a qualitative comparative analysis from the Invested in Diabetes study. | Implementation science communications | Implement Sci Commun | 5 | 1 | 10.1186/s43058-024-00608-6 | eng | 2,024 | 7 | 24 | 2,024 | 7 | 24 | [BACKGROUND] Diabetes is a serious public health problem affecting 37.3 million Americans. Diabetes shared medical appointments (SMAs) are an effective strategy for providing diabetes self-management support and education in primary care. However, practices delivering SMAs experience implementation challenges. This ana... | Diabetes; Health care delivery; Implementation champions; PRISM; Primary care; Qualitative comparative analysis | 1.245 | 26 | Health Informatics; Health Policy; Public Health, Environmental and Occupational Health | Medicine | 2,024 |
39,049,022 | Comparative transcriptomics identifies genes underlying growth performance of the Pacific black-lipped pearl oyster Pinctada margaritifera. | BMC genomics | BMC Genomics | 25 | 1 | 10.1186/s12864-024-10636-0 | eng | 2,024 | 7 | 24 | 2,024 | 7 | 24 | [BACKGROUND] In bivalves, the rate at which organisms grow is a major functional trait underlying many aspects of their commercial production. Growth is a highly polygenic trait, which is typically regulated by many genes with small to moderate effects. Due to its complexity, growth variability in such shellfish remain... | Pinctada margaritifera; Bivalves; Growth; Oysters; RNA-seq | 1.003 | 208 | Biotechnology; Genetics | Biochemistry, Genetics and Molecular Biology | 2,024 |
39,049,010 | Using natural language processing to facilitate the harmonisation of mental health questionnaires: a validation study using real-world data. | BMC psychiatry | BMC Psychiatry | 24 | 1 | 10.1186/s12888-024-05954-2 | eng | 2,024 | 7 | 24 | 2,024 | 7 | 24 | [BACKGROUND] Pooling data from different sources will advance mental health research by providing larger sample sizes and allowing cross-study comparisons; however, the heterogeneity in how variables are measured across studies poses a challenge to this process. [METHODS] This study explored the potential of using natu... | Data pooling; Harmonisation; Meta-analysis; Retrospective data harmonisation | 1.375 | 151 | Psychiatry and Mental Health | Medicine | 2,024 |
39,048,980 | Protective effects of the R-(+)-thioctic acid treatment: possible anti-inflammatory activity on heart of hypertensive rats. | BMC complementary medicine and therapies | BMC Complement Med Ther | 24 | 1 | 10.1186/s12906-024-04547-6 | eng | 2,024 | 7 | 24 | 2,024 | 7 | 24 | [BACKGROUND] In cardiovascular disease, high blood pressure is associated with oxidative stress, promoting endothelial dysfunction, vascular remodeling, and inflammation. Clinical trials are discordant that the most effective treatment in the management of hypertension seems to be the administration of anti-hypertensiv... | Heart; Hypertension; Inflammation; Oxidative stress; Thioctic acid | 0.741 | 123 | Complementary and Alternative Medicine | Medicine | 2,024 |
39,048,932 | Implementation of a fluid balance control strategy in critically ill patients: POINCARE-2 trial process evaluation. | BMC medical research methodology | BMC Med Res Methodol | 24 | 1 | 10.1186/s12874-024-02288-1 | eng | 2,024 | 7 | 24 | 2,024 | 7 | 24 | [BACKGROUND] POINCARE-2 trial aimed to assess the effectiveness of a strategy designed to tackle fluid overload through daily weighing and subsequent administration of treatments in critically ill patients. Even in highly standardized care settings, such as intensive care units, effectiveness of such a complex interven... | Complex intervention; Critical care; Intensive care unit; Process evaluation; Randomized controlled trial | 1.669 | 176 | Epidemiology; Health Informatics | Medicine | 2,024 |
39,048,891 | Knowledge mapping of exosomes in prostate cancer from 2003 to 2022: a bibliometric analysis. | Discover oncology | Discov Oncol | 15 | 1 | 10.1007/s12672-024-01183-x | eng | 2,024 | 7 | 24 | 2,024 | 7 | 24 | [BACKGROUND] Prostate cancer (PCa) is highly prevalent among males worldwide. The investigation of exosomes in PCa has emerged as a dynamic and important research area. To visually depict the prominent research areas and evolutionary patterns of exosomes in PCa, we performed a comprehensive analysis via bibliometric me... | Bibliometrics; CiteSpace; Exosomes; Prostate cancer; VOSviewer | 0.88 | 47 | Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research | Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | 2,024 |
39,048,532 | Glucagon-like peptide agonists for weight management in antipsychotic-induced weight gain: A systematic review and meta-analysis. | Acta psychiatrica Scandinavica | Acta Psychiatr Scand | 150 | 6 | 10.1111/acps.13734 | eng | 2,024 | 12 | null | 2,024 | 7 | 24 | [INTRODUCTION] Managing body weight in patients with antipsychotic-induced weight gain (AIWG) is challenging. Besides lifestyle interventions, pharmacological interventions may contribute to weight loss. This systematic review and meta-analysis evaluated the effect on weight loss and adverse effects of glucagon-like pe... | antipsychotics; obesity | 2.506 | 174 | Psychiatry and Mental Health | Medicine | 2,024 |
39,048,457 | Archetype analysis of the spine-hip relationship identifies distinct spinopelvic profiles. | Orthopaedics traumatology, surgery research : OTSR | Orthop Traumatol Surg Res | 110 | 6 | 10.1016/j.otsr.2024.103944 | eng | 2,024 | 10 | null | 2,024 | 7 | 23 | [INTRODUCTION] The position of the pelvis in the sagittal plane can vary considerably between different functional positions. Adapting the position of the acetabular cup in relation to the alignment between the spine and the hip of each individual, prior to prosthesis placement, can prevent the risk of prosthetic impin... | Archetypes; Artificial intelligence; Impingement; Machine learning; Spine-hip relationship; Spinopelvic mobility; Total hip arthroplasty | null | null | null | null | null |
39,048,398 | Optimizing patient selection for ECMO after pediatric hypothermic cardiac arrest. | Injury | Injury | 56 | 1 | 10.1016/j.injury.2024.111731 | eng | 2,025 | 1 | null | 2,024 | 7 | 20 | [BACKGROUND] In 2004, our level 1 regional pediatric trauma center created a protocol to activate ECMO for children with suspected hypothermic cardiac arrest based on inclusion criteria: serum potassium ≤9, submersion 90 min, and core body temperature 30 °C. In 2017, Pasquier et al. developed a model to help predict th... | Cardiac surgical procedures; Extracorporeal membrane oxygenation; Survival rate; Treatment outcomes | 0.762 | 151 | Emergency Medicine; Surgery; Orthopedics and Sports Medicine | Medicine | 2,024 |
39,048,164 | TCGA Database-Based Screening of Tumor Microenvironment Immunomodulators Related to Bladder Cancer Prognosis. | Annals of clinical and laboratory science | Ann Clin Lab Sci | 54 | 3 | null | eng | 2,024 | 5 | null | null | null | null | [OBJECTIVE] Bladder cancer (BC), as the most common malignant tumor of the urinary tract, has a complex biological behavior. Currently, there are still some limitations in the diagnosis and treatment of BC. Despite the great progress made in immunotherapy, there is still a lack of key genes for the diagnosis of BC. The... | bladder cancer; cancer genome atlas database; immune; prognostic biomarkers; tumor microenvironment | null | null | null | null | null |
39,048,076 | Silymarin suppresses proliferation and PD-L1 expression in colorectal cancer cells and increases inflammatory CD8+ cells in tumor-bearing mice. | Clinics and research in hepatology and gastroenterology | Clin Res Hepatol Gastroenterol | 48 | 8 | 10.1016/j.clinre.2024.102425 | eng | 2,024 | 10 | null | 2,024 | 7 | 22 | [INTRODUCTION] Silymarin as an herbal medicine has shown anticancer effects on tumor cells, while having low toxicity in normal cells. In this study, the effects of Silymarin on proliferation and apoptosis of colorectal cancer cells and its impact on immune response against cancer cells were evaluated in vitro and in v... | CD8+ T cells; Colorectal cancer; PD-L1; Silymarin | 0.752 | 70 | Gastroenterology; Hepatology | Medicine | 2,024 |
39,048,074 | CRISPR/Cas9-mediated neuronal deletion of 5-lipoxygenase alleviates deficits in mouse models of epilepsy. | Journal of advanced research | J Adv Res | 63 | null | 10.1016/j.jare.2024.07.018 | eng | 2,024 | 9 | null | 2,024 | 7 | 22 | [INTRODUCTION] Our previous work reveals a critical role of activation of neuronal Alox5 in exacerbating brain injury post seizures. However, whether neuronal Alox5 impacts the pathological process of epilepsy remains unknown. [OBJECTIVES] To prove the feasibility of neuron-specific deletion of Alox5 via CRISPR-Cas9 in... | Alox5; CRISPR; Cas9; Epilepsy; Gene therapy | 2.576 | 108 | Multidisciplinary | Multidisciplinary | 2,024 |
39,048,021 | Association between positive serology for COVID-19 and chagas cardiomyopathy progression: The SaMi-Trop project. | Travel medicine and infectious disease | Travel Med Infect Dis | 61 | null | 10.1016/j.tmaid.2024.102745 | eng | 2,024 | null | null | 2,024 | 7 | 22 | [BACKGROUND] Chagas Disease (CD) can cause Chagas cardiomyopathy. The new coronavirus disease (COVID-19) also affects the cardiovascular system and may worsen Chagas cardiomyopathy. However, the cardiac evolution of patients with CD infected by COVID-19 is not known. Thus, the objective of this study is to assess, with... | COVID-19; Chagas disease; Disease progression | 0.955 | 77 | Public Health, Environmental and Occupational Health; Infectious Diseases | Medicine | 2,024 |
39,047,950 | Identifying pathways from childhood adversity to suicidal thoughts and behaviors among sexual minority adults: An exploratory mediation analysis. | Journal of affective disorders | J Affect Disord | 363 | null | 10.1016/j.jad.2024.07.082 | eng | 2,024 | 10 | 15 | 2,024 | 7 | 22 | [BACKGROUND] The current study uses a nationally representative longitudinal dataset of sexual minority adults in the US to investigate the pathways from adverse childhood experiences (ACEs) to adulthood suicidal thoughts and behaviors. [METHODS] ACEs were measured at year one, potential mediators at year two, and suic... | Adverse childhood experiences; Exploratory mediation analysis; Sexual minorities; Suicide | 2.121 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,024 |
39,102,175 | A Comparative Analysis of Healthcare Quality Perception Among Different Vulnerable Populations with and without Telehealth Utilization: A Cross-Sectional Study from the Health Information National Trends Survey. | Journal of racial and ethnic health disparities | J Racial Ethn Health Disparities | null | null | 10.1007/s40615-024-02116-8 | eng | 2,024 | 8 | 5 | 2,024 | 8 | 5 | [OBJECTIVE] The COVID-19 pandemic led to a rapid expansion of telehealth utilization in medicine. However, the quality measures associated with telehealth use remain unclear, particularly among vulnerable populations. This study aims to investigate the impact of telehealth on individuals' perception of overall quality ... | null | 1.46 | 56 | Anthropology; Health Policy; Health; Public Health, Environmental and Occupational Health; Sociology and Political Science | Medicine; Social Sciences | 2,024 |
39,102,000 | Cardiovascular magnetic resonance reveals myocardial involvement in patients with active stage of inflammatory bowel disease. | Clinical research in cardiology : official journal of the German Cardiac Society | Clin Res Cardiol | null | null | 10.1007/s00392-024-02503-5 | eng | 2,024 | 8 | 5 | 2,024 | 8 | 5 | [BACKGROUND] Active inflammatory bowel disease (A-IBD) but not remission (R-IBD) has been associated with an increased risk of cardiovascular death and hospitalization for heart failure. [OBJECTIVES] Using cardiovascular magnetic resonance (CMR), this study aims to assess adverse myocardial remodeling in patients with ... | Cardiac remodeling; Extraintestinal manifestation; Inflammation; Ulcerative colitis | 1.514 | 87 | Cardiology and Cardiovascular Medicine; Medicine | Medicine | 2,024 |
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