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39,583,114
Single-cell data revealed the function of natural killer cells and macrophage cells in chemotherapy tolerance in acute myeloid leukemia.
PeerJ
PeerJ
12
null
10.7717/peerj.18521
eng
2,024
null
null
2,024
11
21
[BACKGROUND] Acute myeloid leukemia (AML) is highly prevalent and heterogeneous among adult acute leukemias. Current chemotherapeutic approaches for AML often face the challenge of drug resistance, and AML immune cells play an important role in the regulation of AML drug resistance. Thus, it is of key significance to e...
Acute myeloid leukemia; Chemotherapy resistance; Macrophage cells; Natural killer cells; Single cell RNA-seq
0.625
124
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
39,583,029
The effect of the theory of planned behavior based hand hygiene intervention program on the health outcomes and school absenteeism of the primary school students: Quasi-experimental study.
Journal of infection prevention
J Infect Prev
null
null
10.1177/17571774241300481
eng
2,024
11
22
2,024
11
22
[BACKGROUND] Acute upper respiratory tract infections are the most common infections among school children. Improving water, sanitation, and hygiene facilities in schools is an important intervention for the healthy development of children. The most important component of this intervention is hand washing, which is the...
absenteeism; hand hygiene; health education; infection prevention; school; theory of planned behavior
null
null
null
null
null
39,582,899
Clinical course for pancreatic necrosis and pancreatic pseudocysts due to severe acute or chronic pancreatitis.
Therapeutic advances in gastroenterology
Therap Adv Gastroenterol
17
null
10.1177/17562848241301945
eng
2,024
null
null
2,024
11
23
[BACKGROUND] The acute and chronic pancreatitis (CP) can lead to severe complications like walled-off necrosis, large symptomatic pseudocyst or multiorgan failure. The treatment of these complications is multivariate and can differ from conservative, symptomatic treatment or minimal-invasive, endoscopic transgastral st...
LAMS; endoscopy; necrosectomy; pancreatitis; pseudocyst; walled-off necrosis
1.37
71
Gastroenterology
Medicine
2,024
39,582,783
Influence of the Brain-Derived Neurotrophic Factor Gene Polymorphism on Weight Loss Following Intragastric Balloon Intervention: A Cross-Sectional Study.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
17
null
10.2147/DMSO.S481547
eng
2,024
null
null
2,024
11
19
[BACKGROUND AND AIM] There is noticeable heterogeneity in weight loss outcomes following intragastric balloon (IGB) treatment, with average weight loss ranging between 11% to 15% of total body weight. Genetic variations associated with obesity have been found to influence weight loss response, however such variations a...
BDNF; BMI; intragastric balloon; obesity; polymorphism; weight loss
0.827
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,582,721
Racial disparities in early postoperative proximal humerus fracture outcomes: Do minorities face longer operative times, extended hospital stays, and higher risks?
Shoulder elbow
Shoulder Elbow
null
null
10.1177/17585732241299052
eng
2,024
11
22
2,024
11
22
[BACKGROUND] Racial disparities in orthopedic surgery outcomes have been extensively documented, highlighting systemic biases in care. Proximal humerus fractures (PHFs), about 6% of all fractures, are rising, especially among the elderly. Despite the prevalence of PHFs, a research gap exists regarding racial disparitie...
Proximal humerus fractures; hospital stay; mortality; operation time; postoperative complications; racial disparities; surgical management; unplanned re-intubation
null
null
null
null
null
39,582,504
A Comparison of Different Strategies for Optimizing the Selection of Empiric Antibiotic Therapy for Pneumonia Caused by Gram-Negative Bacteria in Intensive Care Units: Unit-Specific Combination Antibiograms Versus Patient-Specific Risk Factors.
Open forum infectious diseases
Open Forum Infect Dis
11
11
10.1093/ofid/ofae643
eng
2,024
11
null
2,024
10
30
[BACKGROUND] Guidelines suggest dual antipseudomonal therapy for empiric treatment of pneumonia caused by gram-negative bacteria in intensive care unit (ICU) patients. Additionally, consideration of local susceptibility data and patient-specific risk factors for resistance is recommended for selecting optimal empiric r...
antibiogram; empiric antibiotic; intensive care unit; pneumonia; risk factor
1.441
74
Infectious Diseases; Oncology
Medicine
2,024
39,582,448
Changes in skin barrier integrity by electrical impedance spectroscopy during dupilumab treatment on a child with severe atopic dermatitis.
The Turkish journal of pediatrics
Turk J Pediatr
66
5
10.24953/turkjpediatr.2024.4902
eng
2,024
11
16
2,024
11
16
[BACKGROUND] Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal skin barrier dysfunction and altered immune response. Electrical impedance spectroscopy (EIS) has been used as a novel tool to detect skin barrier changes in AD. EIS is a non-invasive measure of the electrical impedanc...
atopic dermatitis; children; dupilumab; electric impedance spectroscopy; epithelium
0.304
41
Pediatrics, Perinatology and Child Health
Medicine
2,024
39,582,181
Galvanising social innovation in gambling harms reduction: a process evaluation of a multi-component Community of Practice.
Global health promotion
Glob Health Promot
null
null
10.1177/17579759241293453
eng
2,024
11
24
2,024
11
24
[BACKGROUND] Communities of Practice (CoPs) are increasingly used in health and non-health sectors globally. Evidence suggests that CoPs can support health promotion activities, but the research mainly encompasses formal, professional contexts: the role and contribution of CoPs in community-centred health promotion has...
VCFSE organisations; collaboration/partnerships; communities of practice; community-centred health promotion; gambling harms; lived experience
null
null
null
null
null
39,581,711
Advanced Nurse Practitioner (ANPs) experiences of the Quality and Outcomes Framework (QOF) Scheme: a UK case study.
BMJ open
BMJ Open
14
11
10.1136/bmjopen-2024-087492
eng
2,024
11
24
2,024
11
24
[OBJECTIVES] The primary focus of pay-for-performance (P4P) schemes in the UK has traditionally been related to the public health and inclusion elements related to the activities of doctors with comparatively less attention given to nursing care as a component of the scheme. However, nursing is an integral part of heal...
Education, Medical; Health Equity; Health policy; Nurses; Primary Care
1.016
176
Medicine
Medicine
2,024
39,581,638
Metabolomic signature of retinal ageing, polygenetic susceptibility, and major health outcomes.
The British journal of ophthalmology
Br J Ophthalmol
109
5
10.1136/bjo-2024-325846
eng
2,025
4
22
2,025
4
22
[BACKGROUND/AIMS] To identify the metabolic underpinnings of retinal aging and examine how it is related to mortality and morbidity of common diseases. [METHODS] The retinal age gap has been established as essential aging indicator for mortality and systemic health. We applied neural network to train the retinal age ga...
Epidemiology; Genetics; Imaging; Public health; Retina
1.806
185
Cellular and Molecular Neuroscience; Ophthalmology; Sensory Systems
Medicine; Neuroscience
2,024
39,581,593
Impact of the COVID-19 Pandemic on Changes in Tobacco Use Behavior: A Longitudinal Cohort Study in Japan.
Journal of epidemiology
J Epidemiol
35
6
10.2188/jea.JE20240180
eng
2,025
6
5
2,025
3
31
[BACKGROUND] Use of novel tobacco products, such as heated tobacco products, has recently increased as a result of being promoted less harmful alternatives to cigarettes. The impact of the coronavirus disease 2019 (COVID-19) pandemic on tobacco use may differ depending on the type of tobacco. [METHODS] We longitudinall...
COVID-19 pandemic; heated tobacco products; tobacco cessation
1.254
95
Epidemiology; Medicine
Medicine
2,024
39,580,853
PERCEPTION OF UROLOGY SPECIALTY AND FACTORS INFLUENCE ITS CONSIDERATION AS A CAREER CHOICE AMONG MEDICAL STUDENTS.
Georgian medical news
Georgian Med News
null
354
null
eng
2,024
9
null
null
null
null
[BACKGROUND] Urology is a branch of medicine that deals with different diseases of the urinary tract or the reproductive organs in both men and women. It is well known that there is an increase in the number of urological diseases that are being encountered in both primary and secondary health services. The purpose of ...
null
null
null
null
null
null
39,580,318
Does multimodal inpatient treatment help some adolescents with severe ARFID?
L'Encephale
Encephale
null
null
10.1016/j.encep.2024.10.001
eng
2,024
11
22
2,024
11
22
[INTRODUCTION] Avoidant Restrictive Food Intake Disorder (ARFID) is a recently described disorder. Data on inpatient treatment is still scarce, ARFID mainly being an outpatient condition. The purpose of this study is to describe a rare population of adolescents with severe ARFID receiving full-time multimodal inpatient...
Adolescent; Avoidant restrictive food intake disorder; Eating disorder; Inpatient; Multidisciplinaire; Multidisciplinary
null
null
null
null
null
39,579,609
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine
136
null
10.1016/j.phymed.2024.156241
eng
2,025
1
null
2,024
11
17
[BACKGROUND] Considering that cardiac microvascular injury may play a more critical role than cardiomyocyte injury in the pathology of early ischaemia/reperfusion (I/R) injury, therapeutic strategies targeting the microvasculature are highly desirable. Palmitic acid-9-hydroxystearic acid (9-PAHSA) is a new class of bio...
9-PAHSA; AMPK/ULK1; Autophagy; Cardiac microvascular ischaemia/reperfusion injury; Mitochondrial homeostasis; STING
1.694
150
Complementary and Alternative Medicine; Drug Discovery; Molecular Medicine; Pharmaceutical Science; Pharmacology
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,578,773
TIMP1 regulates ferroptosis in osteoblasts by inhibiting TFRC ubiquitination: an in vitro and in vivo study.
Molecular medicine (Cambridge, Mass.)
Mol Med
30
1
10.1186/s10020-024-01000-9
eng
2,024
11
23
2,024
11
23
[BACKGROUND] In clinical practice, alterations in the internal environment of type 2 diabetes can significantly affect bone quality. While the increased risk of fractures among diabetic patients is well-established, the precise mechanisms by which hyperglycemia influences bone quality remain largely unclear. [METHODS] ...
Ferroptosis; Iron metabolism; Osteoblast; TFRC; TIMP1; Ubiquitination
1.752
136
Genetics; Genetics; Molecular Biology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,578,755
A Dutch paediatric palliative care guideline: a systematic review and recommendations on advance care planning and shared decision-making.
BMC palliative care
BMC Palliat Care
23
1
10.1186/s12904-024-01568-3
eng
2,024
11
23
2,024
11
23
[BACKGROUND] In paediatric palliative care, children with life-threatening and life-limiting conditions, their families, and their health care professionals often face difficult decisions about treatment, goals of care, and delivery of care. Advance care planning and shared decision-making are strategies that can impro...
Advance care planning; Evidence-based guideline; Paediatric palliative care; Shared decision-making
1.046
62
Medicine
Medicine
2,024
39,578,739
Cerebrospinal fluid IL-6 and IL-10 as promising diagnostic and therapeutic prognostic biomarkers for secondary central nervous system lymphoma.
BMC cancer
BMC Cancer
24
1
10.1186/s12885-024-13195-5
eng
2,024
11
22
2,024
11
22
[BACKGROUND] Accurate diagnosis and therapeutic response to secondary central nervous system lymphoma (SCNSL) are challenges that need to be addressed. We assessed the value of cerebrospinal fluid (CSF) cytokine levels for diagnosis and post-therapeutic prognosis in patients with SCNSL. [METHODS] This retrospective stu...
Biomarker; Cerebrospinal fluid; IL-10; IL-6; SCNSL
1.178
171
Cancer Research; Genetics; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,578,729
Plasma pQTL and brain eQTL integration identifies PNKP as a therapeutic target and reveals mechanistic insights into migraine pathophysiology.
The journal of headache and pain
J Headache Pain
25
1
10.1186/s10194-024-01922-z
eng
2,024
11
22
2,024
11
22
[BACKGROUND] Migraine is a prevalent neurological disorder affecting 14.1% of the global population. Despite advances in genetic research, further investigation is needed to identify therapeutic targets and better understand its mechanisms. In this study, we aimed to identify drug targets and explore the relationships ...
Drug development; Gene regulation; Mendelian randomization; Metabolic pathways; Migraine; Protein expression
2.066
97
Anesthesiology and Pain Medicine; Medicine; Neurology
Medicine
2,024
39,578,620
Diagnostic Concordance Between Physiotherapist and Emergency Physicians for Patients With a Musculoskeletal Disorder in the Emergency Department.
Musculoskeletal care
Musculoskeletal Care
22
4
10.1002/msc.70014
eng
2,024
12
null
null
null
null
[BACKGROUND] Many patients present to the emergency department (ED) with a musculoskeletal disorder. In consequence, some hospitals have integrated autonomous management of musculoskeletal disorders by physiotherapists after triage. Although potential benefits were demonstrated, few studies have examined the agreement ...
diagnostic agreement; emergency department; musculoskeletal disorders; physiotherapy
0.6
38
Chiropractics; Nursing; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Rheumatology
Health Professions; Medicine; Nursing
2,024
39,578,300
Population Pharmacokinetics of Intravenous Paracetamol and Its Metabolites in Extreme Preterm Neonates in the Context of Patent Ductus Arteriosus Treatment.
Clinical pharmacokinetics
Clin Pharmacokinet
63
12
10.1007/s40262-024-01439-3
eng
2,024
12
null
2,024
11
22
[AIMS] Our aim was to describe the pharmacokinetics of paracetamol and its metabolites in extreme preterm neonates in the context of patent ductus arteriosus treatment. Factors associated with inter-individual variability and metabolic pathways were studied. The association between drug exposure and clinical outcomes w...
null
1.305
191
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,578,292
Combined open-robotic 'sandwich' repair for flank hernias: a case series of 10 patients.
Surgical endoscopy
Surg Endosc
39
2
10.1007/s00464-024-11383-9
eng
2,025
2
null
2,024
11
22
[BACKGROUND] Flank hernias represent a rare and technically challenging conundrum for abdominal wall surgeons. Various operative techniques have been attempted including open, laparoscopic, and robotic without an established gold standard. We present a novel technique utilizing a hybrid open-robotic "sandwich" techniqu...
Abdominal wall hernia; Flank hernia; Hernia; Hernia repair; Herniorrhaphy; Incisional hernia; Minimally invasive surgery; Robotic surgery; Traumatic hernia; Traumtic flank hernia
1.023
178
Surgery
Medicine
2,024
39,578,254
A prospective study to evaluate the effectiveness of preventive aspects in relation to sports related ocular injuries.
International ophthalmology
Int Ophthalmol
44
1
10.1007/s10792-024-03357-6
eng
2,024
11
22
2,024
11
22
[BACKGROUND AND OBJECTIVES] Ocular trauma, a major cause of visual morbidity and unilateral blindness globally, sees sports as a prominent contributor. This study aims to assess the effectiveness of preventive measures, combining health education and ocular protective devices, in reducing sports-induced ocular injuries...
Health education; Ocular protection; Sports-related ocular injuries; Unilateral blindness
0.642
57
Ophthalmology
Medicine
2,024
39,578,116
Self-Directed Virtual Reality-Based Training versus Traditional Physician-Led Teaching for Point-of-Care Cardiac Ultrasound: A Randomized Controlled Study.
Journal of cardiothoracic and vascular anesthesia
J Cardiothorac Vasc Anesth
39
1
10.1053/j.jvca.2024.10.037
eng
2,025
1
null
2,024
11
1
[OBJECTIVE] To assess the learning efficacy of self-directed virtual reality ultrasound simulators as an alternative to traditional physician-led teaching for cardiac point-of-care ultrasound (POCUS) training. [DESIGN] Single blinded (observer), noninferiority, parallel group, randomized controlled study. [SETTING] Ter...
cardiovascular; medical education; point-of-care ultrasound; simulation; training; ultrasonography; virtual reality
0.68
100
Anesthesiology and Pain Medicine; Cardiology and Cardiovascular Medicine
Medicine
2,024
39,578,017
Prevalence of medial tibial stress syndrome in the British Armed Forces: a population-based study.
BMJ military health
BMJ Mil Health
null
null
10.1136/military-2024-002788
eng
2,025
3
12
2,025
3
12
[INTRODUCTION] Medial tibial stress syndrome (MTSS) is common in the Armed Forces due to the physical demands placed on service personnel (SP). There are no large studies reporting the extent to which MTSS affects the Armed Forces. A retrospective cross-sectional study design was used to report the annual prevalence of...
EPIDEMIOLOGY; Musculoskeletal disorders; REHABILITATION MEDICINE
0.405
37
Medicine
Medicine
2,024
39,577,834
Infant body composition trajectories differ by in utero exposure to gestational diabetes mellitus: a prospective cohort from birth to 12 months.
The American journal of clinical nutrition
Am J Clin Nutr
121
1
10.1016/j.ajcnut.2024.10.020
eng
2,025
1
null
2,024
11
19
[BACKGROUND] Infants exposed to gestational diabetes mellitus (GDM) in utero are known to have higher fat mass (FM) and less fat-free mass (FFM) at birth, but little is known about how their adiposity changes over the first year of life. [OBJECTIVES] We identified growth and body composition patterns across the first y...
GDM exposed; body composition; catch-down growth; infant growth; infant growth epidemiology; infant growth trajectories; nutritional epidemiology; total body electrical conductivity
2.111
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
39,629,545
Mitral valve transcatheter edge-to-edge repair in the elderly-A safe and effective therapy.
ESC heart failure
ESC Heart Fail
12
3
10.1002/ehf2.15177
eng
2,025
6
null
2,024
12
4
[AIMS] Prevalence of mitral regurgitation (MR) and comorbidity burden rise with age. Mitral valve transcatheter edge-to-edge repair (M-TEER) is increasingly performed in elderly patients, but only limited data are available for this specific subgroup. In this study, outcomes of octogenarians and nonagenarians undergoin...
age; elderly; mitral regurgitation
1.403
57
Cardiology and Cardiovascular Medicine
Medicine
2,024
39,629,396
The sensitivity and specificity of fine needle aspiration cytology in detecting thyroid malignancy according to Bethesda system at a teaching hospital in Saudi Arabia.
Journal of family medicine and primary care
J Family Med Prim Care
13
10
10.4103/jfmpc.jfmpc_432_24
eng
2,024
10
null
2,024
10
18
[BACKGROUND] The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) aims to standardize the terminology and morphologic criteria associated with thyroid fine-needle aspiration cytology (FNAC) results while also providing corresponding risk assessments for malignancy. contributing to more consistent and standa...
Bethesda system; cytology; histopathology; pathology; thyroid
null
null
null
null
null
39,629,369
Can tele-physiotherapy help in filling treatment gaps during pandemics in multiple sclerosis?
Journal of family medicine and primary care
J Family Med Prim Care
13
10
10.4103/jfmpc.jfmpc_204_24
eng
2,024
10
null
2,024
10
18
[BACKGROUND] Published data demonstrate promising results for rehabilitation in patients with multiple sclerosis (MS), including telerehabilitation technologies. Given the travel limitations during the coronavirus disease 2019 (COVID-19), telerehabilitation may provide a viable alternative to in-person physiotherapy. [...
COVID-19 pandemic; India; multiple sclerosis; telerehabilitation; virtual physiotherapy
null
null
null
null
null
39,629,360
A retrospective observational study of orbital cellulitis in children - Recent trends.
Journal of family medicine and primary care
J Family Med Prim Care
13
10
10.4103/jfmpc.jfmpc_847_24
eng
2,024
10
null
2,024
10
18
[PURPOSE] Orbital cellulitis is an acute post-septal orbital infection caused mostly by bacteria. This may result in serious complications including blindness, meningitis, cavernous sinus thrombosis, brain abscess, and even death. The delay in treatment increases morbidity and mortality. The purpose of present study wa...
Acute post-septal orbital infection; ocular problems among children; orbital cellulitis
null
null
null
null
null
39,629,086
Dose-effect relationship in external beam radiotherapy combined with brachytherapy for cervical cancer: A systematic review.
Journal of contemporary brachytherapy
J Contemp Brachytherapy
16
3
10.5114/jcb.2024.140760
eng
2,024
6
null
2,024
6
24
[PURPOSE] External beam radiotherapy with concurrent chemotherapy combined with brachytherapy has been described as the first treatment choice for locally advanced cervical cancer. This study aimed to systematically review the dose-effect relationship (DER) of target volumes and organs at risk (OARs) in external beam r...
brachytherapy; cervical cancer; dose-effect relationship; external beam radiotherapy
0.395
34
Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
39,629,047
Efficacy and safety of once-weekly insulin versus once-daily insulin in patients with type 1 and type 2 diabetes mellitus: an updated meta-analysis of randomized controlled trials.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
15
null
10.3389/fendo.2024.1459127
eng
2,024
null
null
2,024
11
19
[BACKGROUND] This meta-analysis was performed to obtain a comprehensive overview of the differences between once-weekly basal insulin (including icodec and basal insulin Fc) and once-daily basal insulin (including glargine and degludec) in patients with type 1 and type 2 diabetes mellitus. [METHODS] PubMed, EMBASE, and...
diabetes mellitus; glycosylated hemoglobin (HbA1c); hypoglycemia; once-daily insulin; once-weekly insulin
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
39,628,978
Prevalence of chronic kidney disease and associated factors among adult diabetic patients: a hospital-based cross-sectional study.
Frontiers in epidemiology
Front Epidemiol
4
null
10.3389/fepid.2024.1467911
eng
2,024
null
null
2,024
11
19
[BACKGROUND] Chronic kidney disease (CKD) has a significant impact on public health with a high morbidity and death rate. Most diabetic patients, in the course of their lives, develop diabetic kidney disease. In the least developed nations, its size is outstripping itself. This study aimed to determine the prevalence o...
Ethiopia; chronic kidney disease; diabetes mellitus; glomerular filtration rate; prevalence
0.605
8
Health; Infectious Diseases; Public Health, Environmental and Occupational Health; Epidemiology
Medicine; Social Sciences
2,024
39,628,414
Psilocybin as a Disease-Modifying Drug—A Salutogenic Approach in Psychiatry.
Deutsches Arzteblatt international
Dtsch Arztebl Int
121
26
10.3238/arztebl.m2024.0224
eng
2,024
12
27
null
null
null
[BACKGROUND] Treatment with so-called psychedelic drugs, including psilocybin, lysergic acid diethylamide (LSD), and others, is among the most promising recent developments in psychiatry. This review focuses on psilocybin, a substance found in all mushrooms of the genus Psilocybe, because the largest amount of availabl...
null
0.52
97
Medicine
Medicine
2,024
39,627,882
Dynamics of rice seed-borne bacteria from acquisition to seedling colonization.
Microbiome
Microbiome
12
1
10.1186/s40168-024-01978-8
eng
2,024
12
3
2,024
12
3
[BACKGROUND] Rice cultivation relies on planting grains harboring beneficial microbiota. However, the origination, distribution, and transmission dynamics of grain-borne bacteria remain unclear. [RESULTS] Using rice grain as a model system, this study investigates the primary sources, major niches in seeds, and the dyn...
External route; Functional adaptation; Panicle booting and flowering; Quantitative abundance; Rice grain; Seed-borne bacteria
4.117
163
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
39,627,823
Innovative behavior and structural empowerment among the Chinese clinical nurses: the mediating role of decent work perception.
BMC nursing
BMC Nurs
23
1
10.1186/s12912-024-02554-z
eng
2,024
12
3
2,024
12
3
[BACKGROUND] Clinical nurses play a vital role in healthcare. Their innovative behavior is crucial for improving patient care, advancing the profession, and ensuring the healthcare industry's continued success. Many studies have highlighted the importance of nurse innovative behavior, but the link between their innovat...
China; Clinical nurses; Decent work perception; Innovative behavior; Mediating role; Structural empowerment
1.272
62
Nursing
Nursing
2,024
39,627,698
Molecular detection of dengue virus from febrile patients in Ghana.
BMC infectious diseases
BMC Infect Dis
24
1
10.1186/s12879-024-10289-0
eng
2,024
12
3
2,024
12
3
[BACKGROUND] Viral hemorrhagic fevers (VHFs) belong to a group of viral infectious diseases that interfere with the blood's clotting mechanism. VHF has a wide host range, including bats, rodents, or arthropods such as mosquitoes and ticks. Most VHFs emerge suddenly as outbreaks, making it difficult to predict occurrenc...
Dengue fever; Dengue serotypes; Ghana; NGS; Phylogenetics; Viral hemorrhagic fever
1.035
137
Infectious Diseases
Medicine
2,024
39,627,696
Idiopathic recurrent ischemic priapism: a review of current literature and an algorithmic approach to evaluation and management.
Basic and clinical andrology
Basic Clin Androl
34
1
10.1186/s12610-024-00237-y
eng
2,024
12
4
2,024
12
4
[BACKGROUND] Stuttering priapism is characterized by recurrent, self-limited episodes of penile erection lasting from a few minutes to a maximum of three hours, often resolving spontaneously. These episodes can occur with or without sexual stimulation. If not treated promptly and effectively, stuttering priapism can se...
Idiopathic priapism; Ischemic priapism; Management Algorithm; Pathophysiology; Stuttering priapism; Therapeutic agents
null
null
null
null
null
39,627,557
Comparison of short‑ and long‑term outcomes between laparoscopic and open pancreaticoduodenectomy in overweight patients: a propensity score‑matched study.
Surgical endoscopy
Surg Endosc
39
2
10.1007/s00464-024-11418-1
eng
2,025
2
null
2,024
12
3
[BACKGROUND] Overweight is thought to affect the outcome of minimally invasive surgery. There is still a lack of controlled studies of laparoscopic pancreaticoduodenectomy (LPD) versus open pancreaticoduodenectomy (OPD) in overweight patients. This study was designed to compare short-term and long-term outcomes in over...
Laparoscopic pancreaticoduodenectomy; Open pancreaticoduodenectomy; Overweight patients; Propensity score matching
1.023
178
Surgery
Medicine
2,024
39,627,556
Transumbilical single-trocar laparoscopic-assisted cholangiography with a single intraoperative bile duct lavage procedure for inspissated bile syndrome in infants.
Surgical endoscopy
Surg Endosc
39
2
10.1007/s00464-024-11443-0
eng
2,025
2
null
2,024
12
3
[BACKGROUND] To evaluate the feasibility, safety, and efficiency of a novel technique for the diagnosis and treatment of inspissated bile syndrome (IBS) in infants: transumbilical single-trocar laparoscopic-assisted cholangiography with a single intraoperative procedure bile duct lavage (TUSLC). [METHODS] This was a pr...
Inspissated bile syndrome; Laparoscopic surgery; Single trocar
1.023
178
Surgery
Medicine
2,024
39,627,425
Suppression of immobilisation device on wrist radiography to improve fracture visualisation.
European radiology
Eur Radiol
35
6
10.1007/s00330-024-11232-2
eng
2,025
6
null
2,024
12
3
[OBJECTIVES] This study validates the use of CycleGAN-generated wrist radiographs with digitally removed splints, specifically assessing their impact on fracture visualisation. [MATERIALS AND METHODS] We retrospectively collected wrist radiographs from 1748 patients who had imaging before and after splint application a...
Deep learning; Immobilisation devices; Radiography; Splint; Wrist fractures
1.535
182
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
39,627,163
Elevated IL-10 serum levels are associated with slower serological response following syphilis treatment during pregnancy.
International journal of STD & AIDS
Int J STD AIDS
null
null
10.1177/09564624241303816
eng
2,024
12
3
2,024
12
3
[BACKGROUND] Approximately 50% of pregnant individuals treated for syphilis do not achieve a decline in non-treponemal titers by delivery. The serological response in pregnant persons is significantly slower compared to non-pregnant individuals, with unclear pathogenesis and clinical significance. This study aimed to d...
IL-10; Syphilis; immunology; pregnancy; serological response
null
null
null
null
null
39,626,916
Imipramine-mediated Suppression of EGFR Signaling Attenuates Invasive and Progressive Abilities of Hepatocellular Carcinoma Cells.
Anticancer research
Anticancer Res
44
12
10.21873/anticanres.17360
eng
2,024
12
null
null
null
null
[BACKGROUND/AIM] Hepatocellular carcinoma (HCC) is a primary liver cancer with high mortality rates worldwide, necessitating effective therapeutic strategies. Imipramine demonstrates the potential to augment standard treatments of different cancers, highlighting its therapeutic promise in oncology. This study aimed to ...
Hepatocellular carcinoma; epidermal growth factor receptor (EGFR); imipramine; metastasis
null
null
null
null
null
39,626,834
Performance of Urinary Markers in Patients With Suspicious Cystoscopy During Follow-up of Recurrent Non-muscle Invasive Bladder Cancer: BTA Stat, NMP22 BladderChek, UBC Rapid Test, CancerCheck UBC Rapid VISUAL, and Uromonitor in Comparison to Cytology.
Urology
Urology
197
null
10.1016/j.urology.2024.11.056
eng
2,025
3
null
2,024
12
1
[OBJECTIVE] To compare all available rapid tests on a large cohort of recurrent bladder cancer during follow-up in this multicentre-study is the first study. BTA stat, NMP22 BladderChek, UBC Rapid Test CancerCheck UBC rapid VISUAL, and uromonitor are urinary-based rapid tests for bladder cancer detection. [METHODS] In ...
null
0.756
197
Urology
Medicine
2,024
39,626,830
Prevalence of neurogenic stress cardiomyopathy in acute ischemic stroke and relationship with leukocytosis.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
34
1
10.1016/j.jstrokecerebrovasdis.2024.108169
eng
2,025
1
null
2,024
12
1
[OBJECTIVE] Describe the prevalence and features of neurogenic stress cardiomyopathy in acute ischemic stroke. Describe leukocytosis as an inflammatory marker in neurogenic stress cardiomyopathy. [MATERIALS/METHODS] Retrospective review of 688 adult ischemic stroke patients at a tertiary care center (1/2018 - 12/2021)....
acute ischemic stroke; high-density lipoprotein; inflammation; leukocytosis; neurogenic stress cardiomyopathy
0.688
85
Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery
Medicine
2,024
39,626,469
Serum potassium levels as an independent predictor of unplanned enteral nutrition discontinuation in older adults with gastroesophageal reflux disease.
Clinical nutrition (Edinburgh, Scotland)
Clin Nutr
44
null
10.1016/j.clnu.2024.11.029
eng
2,025
1
null
2,024
11
20
[BACKGROUND AND AIMS] Enteral nutrition in older adults is often associated with intolerance, a phenomenon not well-understood in the context of gastroesophageal reflux disease (GERD). This observational study aimed to evaluate serum potassium levels as an independent prognostic factor for unplanned enteral nutrition d...
Elderly; Enteral nutrition; Gastroesophageal reflux disease; Nutrition intolerance; Serum potassium
2.212
183
Critical Care and Intensive Care Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
39,626,379
Reliability of isokinetic dynamometer for isometric assessment of ankle plantar flexor strength.
Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
Phys Ther Sport
71
null
10.1016/j.ptsp.2024.11.001
eng
2,025
1
null
2,024
11
9
[OBJECTIVE] To evaluate isokinetic dynamometer reliability for isometric assessment of plantar flexor (PF) strength. [DESIGN] Cross-sectional. [SETTING] Testing by the same physiotherapist twice during a first session (repeatability) and once during a second session (reproducibility). [PARTICIPANTS] Twenty-two healthy ...
Biodex; Force; Peak torque; Repeatability; Reproducibility; Soleus
1.002
66
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,024
39,625,850
Association Between Quantitative Sialoscintigraphy and Antibody Profiles in Patients With Sjögren or Sicca Syndrome.
Clinical nuclear medicine
Clin Nucl Med
50
2
10.1097/RLU.0000000000005602
eng
2,025
2
1
2,024
12
3
[PURPOSE] This study analyzed the association between anti-Ro/SSA and anti-La/SSB antibody levels with quantitative and visual sialoscintigraphy patterns in patients suspected of having Sjögren or sicca syndrome. [PATIENTS AND METHODS] Medical records of patients who underwent sialoscintigraphy between April 2020 and M...
null
0.653
73
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
39,625,770
Validation of the Turkish Version of the Professional Fulfillment Index.
The western journal of emergency medicine
West J Emerg Med
25
6
10.5811/westjem.21199
eng
2,024
11
null
null
null
null
[INTRODUCTION] Clinician burnout represents a significant occupational hazard among physicians, with a notably high prevalence among emergency physicians. The Stanford Professional Fulfillment Index (PFI) was developed to comprehensively assess various aspects of doctors' work experiences, including professional fulfil...
null
0.76
59
Emergency Medicine; Medicine
Medicine
2,024
39,625,636
Assessing the influence of smoking on inflammatory markers in bacillus Calmette Guérin response among bladder cancer patients: a novel machine-learning approach.
Minerva urology and nephrology
Minerva Urol Nephrol
77
3
10.23736/S2724-6051.24.05876-2
eng
2,025
6
null
2,024
12
3
[BACKGROUND] Approximately 70% of bladder cancer is diagnosed as non-muscle invasive (NMIBC) and inflammation is known to impact the oncological outcomes. Adjuvant intravesical BCG in intermediate/high risk can lower recurrence and progression. The efficacy of intravesical BCG can be impacted by smoking effects on syst...
null
0.974
40
Nephrology; Urology
Medicine
2,024
39,625,485
Sesamol protects against LPS-induced inflammation in rat peritoneal macrophages by promoting SIRT1-induced repression of NF-κB.
Physiology international
Physiol Int
111
4
10.1556/2060.2024.00432
eng
2,025
1
30
2,024
12
3
[OBJECTIVES] Sesamol, a polyphenolic compound isolated from roasted sesame seeds exhibits significant anti-inflammatory effect, but the molecular mechanism is poorly understood. Peritoneal macrophages play a pivotal role in the control of infections and inflammatory pathologies and are also found in injured tissues alo...
EX527; IL-6; SIRT1; lipopolysaccharide; p65; peritoneal macrophages; sesamol
null
null
null
null
null
39,625,431
Allogeneic hematopoietic stem cell transplantation using reduced intensity conditioning regimen for patients with acute myeloid leukemia not in complete remission.
Cytotherapy
Cytotherapy
27
3
10.1016/j.jcyt.2024.11.012
eng
2,025
3
null
2,024
11
17
[BACKGROUND] Allogeneic hematopoietic stem cell transplantation (HSCT) is the only potentially curative treatment option for patients with refractory and relapsed acute myeloid leukemia (R/R AML) not in complete remission. Many studies investigating the prognosis of patients with R/R AML not in remission focused on pat...
acute myeloid leukemia; allogeneic hematopoietic stem cell transplantation; not in complete remission; reduced intensity conditioning regimen
1.007
109
Transplantation; Cancer Research; Cell Biology; Genetics; Immunology; Immunology and Allergy; Oncology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
39,625,225
Direct minimization of normal-tissue toxicity via an NTCP-based IMPT planning method.
Medical physics
Med Phys
52
3
10.1002/mp.17559
eng
2,025
3
null
2,024
12
3
[BACKGROUND] Intensity-modulated proton therapy (IMPT) planning often relies on physical dose constraints to balance tumor control and sparing of organs at risk (OARs). However, focusing solely on these dose objectives does not always minimize the normal-tissue toxicity, which is quantified as normal tissue complicatio...
IMPT planning; NTCP reduction; biological optimization; proton therapy
0.986
218
Biophysics; Medicine; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,625,096
Exploring pre-requisites for clinical learning indicators: A scoping review.
Curationis
Curationis
47
1
10.4102/curationis.v47i1.2540
eng
2,024
11
29
2,024
11
29
[BACKGROUND] Understanding how clinical learning takes place and what could stand as an indicator of clinical learning is crucial. There are existing challenges in the clinical learning environment that require clinical indicators. These serve as accountability standards in settings that have challenges of human resour...
clinical learning; clinical learning indicators; competency-based education; self-directed learning; self-regulation
0.673
30
Advanced and Specialized Nursing; Fundamentals and Skills; Nurse Assisting; Assessment and Diagnosis; Immunology
Immunology and Microbiology; Nursing
2,024
39,624,771
Effect of Low-Dose Esketamine on Postoperative Delirium in Elderly Patients Undergoing Total Hip or Knee Arthroplasty: A Randomized Controlled Trial.
Drug design, development and therapy
Drug Des Devel Ther
18
null
10.2147/DDDT.S477342
eng
2,024
null
null
2,024
11
26
[PURPOSE] Postoperative delirium (POD) is a prevalent and severe complication in elderly patients undergoing major surgery, associated with increased morbidity and mortality. This randomized controlled trial aimed to investigate the effects of low-dose esketamine on the incidence of POD in elderly patients underwent to...
aged; arthroplasty; delirium; esketamine
1.19
108
Drug Discovery; Pharmaceutical Science; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
39,624,682
Impact of physical activity on quality of life in patients with epilepsy in a developing country: A cross-sectional, survey-based study.
eNeurologicalSci
eNeurologicalSci
37
null
10.1016/j.ensci.2024.100533
eng
2,024
12
null
2,024
11
10
[RATIONALE] Patients with epilepsy face different barriers based on ignorance and fear of themselves and others while exercising, this situation complicates attempts at exercise and promotes discrimination against patients. Physical activity has been associated with favorable results in the health of this population an...
Developing country; Epilepsy; Physical activity; Quality of life
0.424
25
Neurology
Neuroscience
2,024
39,624,680
Low Life Essential 8 Score as a Risk Factor for Long-Term Mortality in Chronic Obstructive Pulmonary Disease: A Study Based on the Analysis of NHANES Data from 2007 to 2012.
International journal of chronic obstructive pulmonary disease
Int J Chron Obstruct Pulmon Dis
19
null
10.2147/COPD.S469584
eng
2,024
null
null
2,024
11
27
[AIMS] The purpose of this prospective cohort study was to examine the association of Life Essential 8 (LE8), the recently updated algorithm for quantifying cardiovascular health (CVH) by the American Heart Association (AHA), with the risk of mortality in Chronic Obstructive Pulmonary Disease (COPD) patients. [METHODS]...
cardiovascular disease; chronic obstructive pulmonary disease; life essential 8; mortality
null
null
null
null
null
39,624,677
A multicenter, single-group, open feasibility study of a new individual cognitive behavioral therapy program for adult Japanese patients with attention-deficit/hyperactivity disorder: Study protocol.
PCN reports : psychiatry and clinical neurosciences
PCN Rep
3
4
10.1002/pcn5.70036
eng
2,024
12
null
2,024
12
2
[BACKGROUND] Attention-deficit/hyperactivity disorder (ADHD) symptoms, including executive function, emotional regulation, and motivation, can persist into adulthood and are often associated with mental illnesses. Cognitive behavioral therapy (CBT) may help ADHD adults in Japan, but the lack of studies and the variabil...
ADHD in adulthood; cognitive behavioral therapy; feasibility study; individual CBT
null
null
null
null
null
39,624,613
A Machine-Learning Model Based on Clinical Features for the Prediction of Severe Dysphagia After Ischemic Stroke.
International journal of general medicine
Int J Gen Med
17
null
10.2147/IJGM.S484237
eng
2,024
null
null
2,024
11
28
[BACKGROUND] This study aimed to construct machine-learning models for prediction of severe dysphagia after ischemic stroke based on clinical features and identify significant clinical predictors. [METHODS] Patients hospitalized with dysphagia after ischemic stroke in Affiliated Hospital of Jiangnan University were ret...
dysphagia; ischemic stroke; machine learning; predictive model
null
null
null
null
null
39,624,611
The Usefulness of New Body Indices in Determining the Risk of Cardiovascular Disease in Cases with Obstructive Sleep Apnea Syndrome.
International journal of general medicine
Int J Gen Med
17
null
10.2147/IJGM.S489904
eng
2,024
null
null
2,024
11
26
[PURPOSE] Obstructive Sleep Apnea Syndrome (OSAS) is considered a notable independent risk factor for cardiometabolic disorders. The current study aimed to investigate the efficacy of new anthropometric indices, A Body Shape Index (ABSI) and the Body Roundness Index (BRI), in assessing cardiovascular risk (CVR) and car...
abdominal obesity; anthropometric indices; body roundness index; cardiovascular disease; cardiovascular risk; obstructive sleep apnea syndrome
null
null
null
null
null
39,624,065
Dermatologists' Perceptions and Factors Influencing the Selection of Topical Anti-Inflammatory Agents for Atopic Dermatitis in China: A Cross-Sectional Survey Study.
Clinical, cosmetic and investigational dermatology
Clin Cosmet Investig Dermatol
17
null
10.2147/CCID.S487996
eng
2,024
null
null
2,024
11
28
[OBJECTIVE] Topical corticosteroids (TCS), topical calcineurin inhibitors (TCI), and phosphodiesterase 4 (PDE-4) inhibitors are three common topical anti-inflammatory agents for treating atopic dermatitis (AD). The purpose of our study was to understand Chinese dermatologists' perceptions and the factors influencing th...
atopic dermatitis; dermatologists; influencing factors; perceptions; topical anti-inflammatory agents
0.737
59
Dermatology
Medicine
2,024
39,623,976
Fathers' Experience of Their Child's Paediatric Brain Tumour.
Cancer reports (Hoboken, N.J.)
Cancer Rep (Hoboken)
7
12
10.1002/cnr2.70061
eng
2,024
12
null
null
null
null
[BACKGROUND] This exploratory study explores the impact of paediatric brain cancer on the experiences of the fathers from the time of diagnosis, while most studies have focused on the mothers. [METHODS] The content of interviews conducted with six fathers of children who had brain tumours at the age of approximately 10...
paediatric brain tumours; paternal experiences; qualitative analysis; representations of the child
0.729
24
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,623,939
Implementing Screening and Treatment Pathways for Teens Who Vape in a Community-Based Pediatrics Clinic in Northern California.
The Permanente journal
Perm J
29
1
10.7812/TPP/24.087
eng
2,025
3
14
2,024
12
3
[OBJECTIVES] The purpose of this report was to summarize implementation of universal screening and treatment pathways for youth vaping in a large, community-based health care system in the United States. [METHODS] Data were obtained as a part of routine clinical care and were extracted from medical records weekly for 4...
Teen vaping; addiction medicine; universal screening
0.763
50
Health Policy; Health; Medicine; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
39,623,819
ASSOCIATION OF CONSANGUINITY WITH RECURRENT FOETAL LOSS.
Journal of Ayub Medical College, Abbottabad : JAMC
J Ayub Med Coll Abbottabad
36
3
10.55519/JAMC-03-13860
eng
2,024
null
null
null
null
null
[BACKGROUND] Approximately 25% of all recognized pregnancies result in foetal loss. Women who will experience two consecutive foetal loss is less than 5%, while loss of three or more consecutive pregnancies in the first trimester, termed as Recurrent foetal loss (RFL), occurs in 1% of all pregnancies. RFL is often asso...
null
null
null
null
null
null
39,623,509
A qualitative study of perceptions of the care pathway for familial hypercholesterolemia: screening, diagnosis, treatment, and family cascade screening.
Implementation science communications
Implement Sci Commun
5
1
10.1186/s43058-024-00670-0
eng
2,024
12
2
2,024
12
2
[BACKGROUND] Familial hypercholesterolemia (FH) is an autosomal dominant genetic condition that carries increased risk for premature atherosclerotic cardiovascular disease, cardiovascular events, and death. Due to low uptake of evidence-based practices, up to 80% of FH patients remain undiagnosed and most are undertrea...
Barriers to care; Care pathway; Cascade screening; FIND FH; Familial hypercholesterolemia; Implementation science; Machine learning; Underdiagnosis
1.245
26
Health Informatics; Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
39,623,312
Expression quantitative trait loci influence DNA damage-induced apoptosis in cancer.
BMC genomics
BMC Genomics
25
1
10.1186/s12864-024-11068-6
eng
2,024
12
2
2,024
12
2
[BACKGROUND] Genomic instability and evading apoptosis are two fundamental hallmarks of cancer and closely linked to DNA damage response (DDR). By analyzing expression quantitative trait loci (eQTL) upon cell stimulation (called exposure eQTL (e[2]QTL)) it is possible to identify context specific gene regulatory varian...
Apoptosis; Cancer; DNA damage; GWAS; eQTL
1.003
208
Biotechnology; Genetics
Biochemistry, Genetics and Molecular Biology
2,024
39,623,055
Salvage irreversible electroporation for locally recurrent prostate cancer after definitive radiotherapy: a systematic review.
Prostate cancer and prostatic diseases
Prostate Cancer Prostatic Dis
null
null
10.1038/s41391-024-00926-9
eng
2,024
12
2
2,024
12
2
[BACKGROUND] To systematically evaluate the available evidence regarding the effect of salvage irreversible electroporation (IRE) in patients with local recurrent prostate cancer (PCa) after definitive radiotherapy (RT). [METHODS] A systematic search was conducted in the electronic databases PubMed-MEDLINE and the Web ...
null
1.962
81
Cancer Research; Oncology; Urology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,622,767
Clinical, Immunologic, and Genetic Characteristics in Patients With Syndrome of Undifferentiated Recurrent Fevers.
Arthritis rheumatology (Hoboken, N.J.)
Arthritis Rheumatol
77
5
10.1002/art.43065
eng
2,025
5
null
2,024
12
29
[OBJECTIVE] Syndrome of undifferentiated recurrent fevers (SURF) is characterized by recurrent fevers and autoinflammation without a confirmed molecular diagnosis of a hereditary recurrent fever syndrome, and not fulfilling criteria for periodic fever, adenitis, pharyngitis, aphthous stomatitis syndrome (PFAPA). The go...
null
null
null
null
null
null
39,622,572
SPOON: an observational, cross-sectional study of perceptions and expectations of adults with generalised myasthenia gravis in France.
BMJ open
BMJ Open
14
12
10.1136/bmjopen-2024-088813
eng
2,024
12
2
2,024
12
2
[OBJECTIVES] To capture patient perceptions about living with myasthenia gravis (MG) with respect to aspirations and ways to improve treatment. [DESIGN] Online patient survey. [SETTING] Patients recruited by MG patient associations or at MG reference treatment centres. [PARTICIPANTS] Adults with physician-diagnosed gen...
Neuromuscular disease; Patient Reported Outcome Measures; Patient Satisfaction; Quality of Life
1.016
176
Medicine
Medicine
2,024
39,622,357
Randomized clinical trial comparing mixed liposomal bupivacaine vs. continuous catheter for interscalene block during shoulder arthroplasty: a comparison of analgesia, patient experience, and cost.
Journal of shoulder and elbow surgery
J Shoulder Elbow Surg
null
null
10.1016/j.jse.2024.09.051
eng
2,024
11
30
2,024
11
30
[BACKGROUND] Continuous interscalene catheters extend analgesia beyond 24 hours but are resource-intensive, while the efficacy of liposomal bupivacaine for single-injection interscalene blocks (ISBs) remains uncertain. The purpose of this investigation was to examine the analgesic efficacy, quality of recovery, and tre...
Interscalene nerve block; liposomal bupivacaine; pain management; shoulder arthroplasty; time-drive activity-based cost; value-based health care
1.741
178
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,024
39,622,350
Allergy and autoinflammation drive persistent systemic inflammatory response in Meniere Disease: A longitudinal study.
Clinical immunology (Orlando, Fla.)
Clin Immunol
271
null
10.1016/j.clim.2024.110413
eng
2,025
2
null
2,024
11
30
[BACKGROUND] Meniere disease (MD), an inner ear disorder influenced by genetic and environmental factors, potentially leads to chronic inflammation. This study evaluates whether inflammation in MD patients is driven by allergy or autoinflammation. [METHODS] 2-year longitudinal study. Cytokine and chemokine levels were ...
Cytokines; IgE; Inflammation; Meniere Disease
1.279
145
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
39,621,985
Predicting Responses to Interventional Pain Management Techniques for Chronic Low Back Pain: A Single-Center Observational Study (PReTi-Back Study).
Pain physician
Pain Physician
27
8
null
eng
2,024
11
null
null
null
null
[BACKGROUND] Exploring factors linked to the outcomes of certain interventional pain management techniques may optimize the selection of candidates for those procedures. Our hypothesis is that factors that influence responses to interventional therapies for chronic low back pain (CLBP) can be identified by analyzing a ...
epidural injections; interventional pain management; logistic regression; medial branch therapies; outcome assessment; predictive factors; predictive model; tailored medicine; treatment response; Chronic low back pain
null
null
null
null
null
39,621,862
Semiology Extraction and Machine Learning-Based Classification of Electronic Health Records for Patients With Epilepsy: Retrospective Analysis.
JMIR medical informatics
JMIR Med Inform
12
null
10.2196/57727
eng
2,024
10
17
2,024
10
17
[BACKGROUND] Obtaining and describing semiology efficiently and classifying seizure types correctly are crucial for the diagnosis and treatment of epilepsy. Nevertheless, there exists an inadequacy in related informatics resources and decision support tools. [OBJECTIVE] We developed a symptom entity extraction tool and...
China; Chinese; decision support tools; diagnosis; electronic health record; epilepsy; health records; machine learning; natural language processing; ontology; retrospective analysis; seizure; semiology; symptom; treatment; unstructured text
1.007
55
Health Information Management; Health Informatics
Health Professions; Medicine
2,024
39,620,570
Comparison of Analgesic Efficacy between Ultrasound-guided Supra-inguinal Fascia Iliaca Block and Pericapsular Nerve Group Block following Total Hip Arthroplasty: A Randomized Controlled Trial.
Hip pelvis
Hip Pelvis
36
4
10.5371/hp.2024.36.4.290
eng
2,024
12
1
null
null
null
[PURPOSE] The effectiveness of pericapsular nerve group (PENG) block versus suprainguinal fascia iliaca block (SFIB) for pain relief after hip arthroplasty is a topic of ongoing debate. This study aimed to examine the association of PENG block with lower consumption of opioids during the first 24 hours following surger...
Nerve blockades; Peripheral nerves; Postoperative pain; Total hip arthroplasty; Ultrasound
null
null
null
null
null
39,620,298
Clinical Significance of Coronary Artery Tortuosity in Chronic Coronary Syndrome and Stable Angina: Insights from Gensini Scores.
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
Turk Kardiyol Dern Ars
52
8
10.5543/tkda.2024.87425
eng
2,024
12
null
null
null
null
[OBJECTIVE] This study investigated the clinical significance of coronary artery tortuosity (CAT) in chronic coronary syndrome (CCS) using Gensini scores. [METHOD] This retrospective single-center study involved 388 patients undergoing coronary angiography for chest pain, excluding those with acute coronary syndromes o...
null
null
null
null
null
null
39,620,183
Clinical Profile of Non-thyroidal Cancer Patients with Tyrosine Kinase Inhibitor-induced Thyroid Dysfunction in the University of Santo Tomas Hospital, Philippines: A 5-Year Single-center Retrospective Study.
Journal of the ASEAN Federation of Endocrine Societies
J ASEAN Fed Endocr Soc
39
2
10.15605/jafes.039.02.14
eng
2,024
null
null
2,024
9
5
[OBJECTIVES] This study aimed to determine the clinical profile of non-thyroidal cancer patients with thyroid dysfunction associated with tyrosine kinase inhibitor (TKI) therapy at the University of Santo Tomas Hospital (USTH), Philippines. [METHODOLOGY] This is a retrospective observational study of TKI-initiated adul...
hyperthyroidism; hypothyroidism; tyrosine kinase inhibitors
0.329
10
Endocrinology, Diabetes and Metabolism; Endocrinology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,619,922
Testosterone hormone levels and breast muscle performance of Pelung chickens after zinc sulfate and synthetic testosterone supplementation.
Veterinary world
Vet World
17
10
10.14202/vetworld.2024.2365-2369
eng
2,024
10
null
2,024
10
27
[BACKGROUND AND AIM] Pelung chicken Gallus gallus gallus (Linnaeus, 1758) is a chicken endemic to Cianjur, West Java, Indonesia. This study aimed to determine the effects of zinc sulfate (ZnSO4) and synthetic testosterone supplementations for 56 days on testosterone hormone levels and breast muscle performance in Pelun...
Pelung chicken; muscle; performance; testosterone; texture
0.541
56
Veterinary
Veterinary
2,024
39,619,794
Deep learning based on multiparametric MRI predicts early recurrence in hepatocellular carcinoma patients with solitary tumors ≤5 cm.
European journal of radiology open
Eur J Radiol Open
13
null
10.1016/j.ejro.2024.100610
eng
2,024
12
null
2,024
11
15
[PURPOSE] To evaluate the effectiveness of a constructed deep learning model in predicting early recurrence after surgery in hepatocellular carcinoma (HCC) patients with solitary tumors ≤5 cm. [MATERIALS AND METHODS] Our study included a total of 331 HCC patients who underwent curative resection, with all patients havi...
Deep learning; Early, recurrence; Hepatocellular carcinoma; Magnetic resonance imaging
0.706
29
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
39,619,673
Subtyping colorectal cancer based on septic shock-associated genes: prognosis and immune characteristics.
Frontiers in genetics
Front Genet
15
null
10.3389/fgene.2024.1468424
eng
2,024
null
null
2,024
11
15
[BACKGROUND] Sepsis and colorectal cancer (CRC) are leading causes of death. Given their mutual dependence for susceptibility, we used bioinformatics to explore potential connections between septic shock (SS) and CRC. [METHODS] We identified 452 co-expressed genes between SS-related differential expression genes (SS-DE...
clustering; colorectal cancer; immune; sepsis; septic shock
0.863
135
Genetics; Genetics; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,619,223
Clinical Characteristics, Risk Factors, and Predictors of Nonobese Fatty Liver Disease: A Cross-Sectional Study.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
17
null
10.2147/DMSO.S482638
eng
2,024
null
null
2,024
11
25
[PURPOSE] This study aimed to investigate the risk factors and predictors of non-obese fatty liver disease in the Chinese population. [PATIENTS AND METHODS] A total of 6,014 adults who underwent physical examinations at Union Hospital of Huazhong University of Science and Technology from March 2019 to March 2023 were i...
Clinical Features; Fatty liver; Forecasting; Non-obese type; Risk Factors
0.827
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,619,196
The applications of anterior segment optical coherence tomography in glaucoma: a 20-year bibliometric analysis.
PeerJ
PeerJ
12
null
10.7717/peerj.18611
eng
2,024
null
null
2,024
11
28
[OBJECTIVE] In the past 20 years, the research application of anterior segment optical coherence tomography (AS-OCT) in the field of glaucoma has become a hot topic, but there is still a lack of bibliometric reports on this scientific field. The aim of this study is to explore the research hotspots and trends in the fi...
Bibliometric analysis; Data visualization; Deep learning; Glaucoma; Research hotspots trends
0.625
124
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
39,619,067
Urothelial genotoxicity of environmental chemicals detected in the urine of healthy dogs and their owners.
Journal of clinical and translational science
J Clin Transl Sci
8
1
10.1017/cts.2024.546
eng
2,024
null
null
2,024
10
24
[INTRODUCTION] Major risk factors for urothelial cell carcinoma (UCC) in people are smoking and occupational exposures. However, up to 30% of human UCC risk is still unexplained. Pet dogs develop UCC that models the clinical behavior of muscle-invasive human UCC. Dogs may therefore provide a useful model for non-tobacc...
Bladder cancer; acrolein; arsenic; environmental chemicals; urothelial carcinoma risk
0.857
19
Medicine
Medicine
2,024
39,618,714
Effect of dietary approaches to stop hypertension and curcumin co-administration on glycemic parameters in polycystic ovary syndrome: An RCT.
International journal of reproductive biomedicine
Int J Reprod Biomed
22
9
10.18502/ijrm.v22i9.17473
eng
2,024
9
null
2,024
11
14
[BACKGROUND] olycystic ovary syndrome (PCOS) is an endocrine disorder that can lead to major reproductive and metabolic complications. Management of glycemic parameters is an important step to improve the symptoms of PCOS. [OBJECTIVE] This study aims to evaluate the effects of the dietary approaches to stop hypertensio...
Curcumin; Dietary approaches to stop hypertension; Glycemic control.; Insulin resistance; Polycystic ovary syndrome
0.519
48
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,024
39,618,428
A Comparative Study of Esketamine-Propofol and Sufentanil-Propofol for Analgesia and Sedation During Breast Minimally Invasive Rotary Resection with Local Anesthesia: A Randomized Double-Blind Clinical Trial.
Drug design, development and therapy
Drug Des Devel Ther
18
null
10.2147/DDDT.S487872
eng
2,024
null
null
2,024
11
25
[PURPOSE] Minimally invasive rotary resection (MIRR) is crucial for diagnosing and treating breast tumors, but the optimal intravenous anesthesia regimen is unclear. Esketamine, an NMDA receptor antagonist with anesthetic, analgesic, and sympathomimetic properties, may provide an ideal adjunct to propofol sedation. Thi...
breast tumor; esketamine; hypoxia; minimally invasive rotary resection; respiratory depression
1.19
108
Drug Discovery; Pharmaceutical Science; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
39,618,155
Perioperative Antidepressant Use is Associated With Symptomatic Pseudarthrosis After Lumbar Fusion.
Spine
Spine (Phila Pa 1976)
50
16
10.1097/BRS.0000000000005235
eng
2,025
8
15
2,024
12
2
[STUDY DESIGN] Retrospective cohort. [OBJECTIVE] To explore the relationship between symptomatic pseudoarthrosis requiring revision after lumbar fusion and antidepressant use. [SUMMARY OF BACKGROUND DATA] Approximately 25% of patients undergoing spine surgery are taking antidepressants. Pseudoarthrosis is a significant...
antidepressants; lumbar fusion; outcome; pseudarthrosis; revision; spine; surgery
1.216
300
Neurology; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,024
39,618,097
Effects of probiotic supplementation with high-intensity interval training on cardiorespiratory endurance and metabolism in Middle-Aged Obese Women.
Journal of the International Society of Sports Nutrition
J Int Soc Sports Nutr
21
1
10.1080/15502783.2024.2425609
eng
2,024
12
null
2,024
12
1
[INTRODUCTION] High-intensity interval training (HIIT) has been shown to improve chronic diseases. Probiotics have been found to have similar effects. However, the additive effects of HIIT in combination with probiotics supplementation are unclear. The aim of current study was to investigate whether there were additive...
Lactiplantibacillus plantarum TWK10; gut microbiota; maximal oxygen uptake; obese women; running economy; time to exhaustion
1.316
74
Food Science; Nutrition and Dietetics; Sports Science
Agricultural and Biological Sciences; Health Professions; Nursing
2,024
39,617,180
Oral care pathways after oral mucosal graft harvesting: a systematic review.
Actas urologicas espanolas
Actas Urol Esp (Engl Ed)
49
1
10.1016/j.acuroe.2024.11.002
eng
2,025
null
null
2,024
11
29
[INTRODUCTION] Oral mucosal grafts are essential in reconstructive urology, particularly for urethral and genital defects. Advances in harvesting and implantation techniques have been made, yet perioperative care remains crucial for optimal outcomes. This systematic review explores postoperative care pathways following...
BMG; Cuidados postoperatorios tras IMO; IMB; IML; Injerto de mucosa oral; LMG; OMG graft harvesting; OMG post-operative care; Oral care pathways; Oral mucosal graft
0.44
30
Urology
Medicine
2,024
39,617,032
Dorsal cortex line is more reliable than transepicondylar axis for rotation in revision total knee arthroplasty with severe bone loss.
Bone joint open
Bone Jt Open
5
12
10.1302/2633-1462.512.BJO-2024-0140.R1
eng
2,024
12
2
2,024
12
2
[AIMS] The transepicondylar axis is a well-established reference for the determination of femoral component rotation in total knee arthroplasty (TKA). However, when severe bone loss is present in the femoral condyles, rotational alignment can be more complicated. There is a lack of validated landmarks in the supracondy...
null
null
null
null
null
null
39,616,982
Unlocking insights: Using machine learning to identify wasting and risk factors in Egyptian children under 5.
Nutrition (Burbank, Los Angeles County, Calif.)
Nutrition
131
null
10.1016/j.nut.2024.112631
eng
2,025
3
null
2,024
11
12
[INTRODUCTION] Malnutrition, particularly wasting, continues to be a significant public health issue among children under five years in Egypt. Despite global advancements in child health, the prevalence of wasting remains a critical concern. This study employs machine learning techniques to identify and analyze the det...
Child nutrition; Egypt; Machine learning; Public health; Wasting; Weight-for-height Z-scores
0.961
168
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Medicine; Nursing
2,024
39,616,851
Exploring molecular mechanism of Panlongqi Tablet (PLQT) against RA: Integrated network pharmacology, molecular docking and experiment validation.
International immunopharmacology
Int Immunopharmacol
144
null
10.1016/j.intimp.2024.113639
eng
2,025
1
10
2,024
11
30
[BACKGROUND AND PURPOSE] Panlongqi Tablet (PLQT), a proprietary Chinese medicine composed of 29 herbs, has been included in the Chinese Medical Insurance List and has shown promising therapeutic effects on patients with rheumatoid arthritis (RA) in clinical practice. However, the molecular mechanisms of PLQT against RA...
Network pharmacology; Panlongqi tablet; RAW264.7 macrophages; Rheumatoid arthritis; Synovial angiogenesis; T lymphocytes
1.239
155
Pharmacology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,616,826
Maturational delay in the brainstem auditory pathway of very preterm babies with apnoea.
Early human development
Early Hum Dev
200
null
10.1016/j.earlhumdev.2024.106164
eng
2,025
1
null
2,024
11
28
[AIMS] To assess the maturational status of the brainstem auditory pathway in babies with apnoea of prematurity (AOP) at 33-34 weeks of postmenstrual age (PMA), an important time landmark at which AOP is resolved in most cases. [STUDY DESIGN] Compare brainstem auditory maturation between very preterm babies with AOP an...
Apnoea; Auditory evoked potentials; Brainstem auditory maturation; Neonatal hypoxia; Perinatal brain damage
0.815
115
Pediatrics, Perinatology and Child Health; Obstetrics and Gynecology
Medicine
2,024
39,616,473
The impact of HIV antiretroviral therapy on gut microbiota: the need for well-designed longitudinal studies.
Journal of infection in developing countries
J Infect Dev Ctries
18
10
10.3855/jidc.18878
eng
2,024
10
31
2,024
10
31
[INTRODUCTION] Human immunodeficiency virus (HIV) infection remains a major public health concern despite a significant decline in HIV-related mortality and morbidity. These significant advances are linked mostly to effective antiretroviral therapy (ART). However, these treatments are not without consequences on other ...
HIV antiretroviral-therapy; longitudinal studies; microbiota dysbiosis
0.389
64
Infectious Diseases; Medicine; Microbiology; Parasitology; Virology
Immunology and Microbiology; Medicine
2,024
39,616,409
Klotho protein: a new insight into the pathogenesis of essential hypertension.
Clinical hypertension
Clin Hypertens
30
1
10.1186/s40885-024-00294-5
eng
2,024
12
1
2,024
12
1
[BACKGROUND] Essential hypertension is a most prevalent global health concern. Despite extensive research, the exact mechanisms contributing to essential hypertension remain unclear. Several factors contribute to the pathogenesis of essential hypertension. Klotho, a membrane-bound and soluble protein, has been found to...
Essential hypertension; Fibroblast growth factor-23; Klotho protein; Wingless-related integration site pathway
1.06
25
Cardiology and Cardiovascular Medicine; Internal Medicine
Medicine
2,024
39,616,310
Management of large or giant Extracranial carotid artery aneurysms: a single-center experience.
BMC neurology
BMC Neurol
24
1
10.1186/s12883-024-03970-z
eng
2,024
11
30
2,024
11
30
[BACKGROUND] Extracranial carotid artery aneurysm (ECCA) is an infrequent disease with an incidence of less than 1%. However, our understanding is still incomplete, and the preferred method to treat ECAA remains unknown. [METHODS] To share our initial experience with treatment options for large ECCAs. We have retrospec...
Aneurysm; Carotid artery disease; Endovascular treatment; Surgical treatment
0.774
100
Medicine; Neurology
Medicine
2,024
39,616,011
Adverse events of mepolizumab in the treatment of nasal polyps: A FDA database evaluation.
American journal of otolaryngology
Am J Otolaryngol
46
1
10.1016/j.amjoto.2024.104517
eng
2,025
null
null
2,024
11
26
[BACKGROUND] Mepolizumab has shown significant efficacy in managing eosinophil-associated disorders such as eosinophilic asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). Despite the advancements in treatment options for CRSwNP, traditional therapies often fail to prevent polyp recurrence and come with subs...
Adverse outcomes; Adverse reactions; Asthma; Chronic rhinosinusitis with nasal polyps; Mepolizumab; Serious outcomes; Serious reactions
null
null
null
null
null
39,615,873
Prevalence and risk factors for bacteremia in community-acquired pneumonia: A systematic review and meta-analysis.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Int J Infect Dis
151
null
10.1016/j.ijid.2024.107312
eng
2,025
2
null
2,024
11
29
[BACKGROUND] Bacteremia represents a significant complication in patients with community-acquired pneumonia (CAP). Nonetheless, there is currently a dearth of systematic research that determines the precise prevalence and risk factors of bacteremia in CAP patients. [METHODS] PubMed, Cochrane Library, Embase, and Web of...
Bacteremia; Community-acquired pneumonia; Meta-analysis; Prevalence; Risk factors
1.323
140
Infectious Diseases; Medicine; Microbiology
Medicine
2,024
39,615,634
Effectiveness of acupuncture on glycolipid metabolism in patients with coronary heart disease: A systematic review and meta-analysis.
Complementary therapies in medicine
Complement Ther Med
88
null
10.1016/j.ctim.2024.103115
eng
2,025
3
null
2,024
11
29
[OBJECTIVE] Disorders of glycolipid metabolism are important pathogenic factors leading to coronary artery disease, and there is no safe and effective comprehensive treatment, while acupuncture has a certain efficacy in heart disease and disorders of glycolipid metabolism. To assess the effects of acupuncture on glycol...
Acupuncture; Coronary heart disease; Glycolipid metabolism; Meta-analysis
1.018
86
Advanced and Specialized Nursing; Complementary and Alternative Medicine; Complementary and Manual Therapy
Health Professions; Medicine; Nursing
2,024
39,615,587
Matrix glycosaminoglycans and proteoglycans in human cornea organoids and similarities with fetal corneal stages.
The ocular surface
Ocul Surf
35
null
10.1016/j.jtos.2024.11.007
eng
2,025
1
null
2,024
11
28
[PURPOSE] We developed human cornea organoids (HCOs) from induced pluripotent stem cells (iPSCs) where single-cell RNA-sequence (scRNA-seq) analysis suggested similarity with developing rather than mature human corneas. We performed immunohistology to determine the presence of corneal glycosaminoglycans as an assessmen...
Cornea; Extracellular matrix; Fetal eye; Glycosaminoglycans; Organoids; Proteoglycans; Single-cell RNA sequencing
1.82
93
Ophthalmology
Medicine
2,024
39,615,212
CIP2A inhibitors TD52 and Ethoxysanguinarine promote macrophage autophagy and alleviates acute pancreatitis by modulating the AKT-mTOR pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine
136
null
10.1016/j.phymed.2024.156263
eng
2,025
1
null
2,024
11
19
[BACKGROUND] Acute pancreatitis (AP) is a prevalent and serious condition within the digestive system, with approximately 20 % to 30 % of cases advancing to severe acute pancreatitis (SAP). During the initial phases of SAP, macrophages are activated in response to the substantial amounts of acinar cell contents and dam...
AKT/mTOR pathway; Acute pancreatitis; Autophagy; CIP2A; Macrophages
1.694
150
Complementary and Alternative Medicine; Drug Discovery; Molecular Medicine; Pharmaceutical Science; Pharmacology
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,615,204
Intrauterine adhesions assessment by photoacoustic imaging versus high frequency ultrasound imaging in rats.
Biochemical and biophysical research communications
Biochem Biophys Res Commun
741
null
10.1016/j.bbrc.2024.151037
eng
2,024
12
31
2,024
11
20
[OBJECTIVE] To compare the sensitivity of photoacoustic imaging (PAI) in the detection of Intrauterine adhesions (IUA) at different grades with that of high frequency ultrasound (US), and to investigate whether PAI can evaluate IUA noninvasively and quantitatively by monitoring endometrial oxygenation. [MATERIALS AND M...
Fibrosis; Intrauterine adhesions; Oxygenation; Photoacoustic imaging; Ultrasonic imaging
0.748
298
Biochemistry; Biophysics; Cell Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,024
39,614,994
Nationwide trends in sadness, suicidal ideation, and suicide attempts among multicultural and monocultural adolescents in South Korea during the COVID-19 pandemic, 2011-2022.
World journal of pediatrics : WJP
World J Pediatr
20
12
10.1007/s12519-024-00858-3
eng
2,024
12
null
2,024
11
30
[BACKGROUND] Researches on the mental health of Korean adolescents during COVID-19 have largely focused on those from monocultural families, but there is limited data on sadness, suicidal ideation, and suicide attempts in multicultural adolescents. [METHODS] This nationwide serial cross-sectional study included 688,708...
COVID-19; Multicultural adolescents; Sadness; South Korea; Suicidal ideation; Suicide attempts
1.05
51
Pediatrics, Perinatology and Child Health
Medicine
2,024