title stringlengths 7 332 | abstract stringlengths 0 6.99k | subjareas listlengths 1 6 | keywords listlengths 0 47 | asjc listlengths 1 8 | body_text listlengths 21 5.39k | author_highlights listlengths 0 21 |
|---|---|---|---|---|---|---|
Nonlinear non-collinear ultrasonic detection and characterisation of kissing bonds | The development of cost effective and reliable bonded structures ideally requires an NDT method to detect the presence of poor quality, weak bonds or kissing bonds. If these bonds are more compliant in tension than in compression stress-strain nonlinearities provide a possible route to detection with the use of nonline... | [
"ENGI",
"MATE",
"PHYS"
] | [
"CAN",
"Kissing bond",
"NDE",
"NDT",
"Non-collinear",
"Nonlinear",
"Ultrasonic"
] | [
"2210",
"2500",
"3104"
] | [
"Kissing bonds, two surfaces in intimate contact but not bonded together, can be difficult to detect with the non-destructive testing (NDT) techniques that are standard in industry today [1,2].",
"For this reason, some structures are over-engineered to allow for the safe failure of an adhesive joint; ‘chicken riv... | [] |
Ultraviolet radiation as a ballast water treatment strategy: Inactivation of phytoplankton measured with flow cytometry | This study investigates different UV doses (mJ/cm2) and the effect of dark incubation on the survival of the algae Tetraselmis suecica, to simulate ballast water treatment and subsequent transport.Samples were UV irradiated and analyzed by flow cytometry and standard culturing methods. Doses of ≥400 mJ/cm2 rendered ina... | [
"AGRI",
"EART",
"ENVI"
] | [
"Dark incubation",
"Esterase substrate",
"Flow cytometry",
"Inactivation",
"Tetraselmis suecica",
"Ultraviolet irradiation"
] | [
"1104",
"1910",
"2310"
] | [
"Ships use water as ballast to ensure stability and trim during the voyage, and ambient water is pumped into ballast tanks in the hull of the ships.",
"It is traditionally discharged without any treatment and represents a global vector for aquatic invasion.",
"A multitude of organisms like virus, bacteria, alga... | [
"Response of T. suecica to different UV doses and dark incubation was determined.",
"Flow cytometry and standard culturing methods were used to determine inactivation.",
"Inactivation increased with increasing doses and with time of dark incubation after treatment.",
"UV doses ≥ 400 mJ/cm2 permanently inactiv... |
Whole cell biosynthesis of 1-methyl-3-phenylpropylamine and 2-amino-1,3,4-butanetriol using Komagataella phaffii (Pichia pastoris) strain BG-10 engineered with a transgene encoding Chromobacterium violaceum ω-transaminase | We have engineered strain BG-10 of the methylotrophic yeast Komagataella phaffii for use as an effective whole cell biocatalyst. We introduced into the yeast a transgene encoding a Chromobacterium violaceum ω-transaminase for transcription in response to methanol induction. The strain was then assessed with respect to ... | [
"MULT"
] | [
"Bioengineering",
"Biotechnology",
"Chemical engineering",
"Komagataella phaffii",
"Pichia pastoris",
"Transaminase",
"Whole cell biocatalyst"
] | [
"1000"
] | [
"The unicellular methylotrophic yeast Komagataella phaffii (K. phaffii), formerly known as Pichia pastoris (Kurtzman, 2009), is a well-established platform for heterologous protein production (Byrne, 2015; Macauley-Patrick et al., 2005).",
"The initial genome sequence of K. phaffii (De Schutter et al., 2009; Kübe... | [] |
Cognitive and anatomical data in a healthy cohort of adults | We present data from a sample of 190 healthy adults including assessments of 4 cognitive factor scores, 12 cognitive tests, and 115 MRI-assessed neuroanatomical variables (cortical thicknesses, cortical and sub-cortical volumes, fractional anisotropy, and radial diffusivity). These data were used in estimating underlyi... | [
"MULT"
] | [
"Fluid intelligence",
"Independent component analysis",
"Individual differences",
"Neuroanatomy",
"Tractography"
] | [
"1000"
] | [
"The data (Supplementary Table 1) includes cognitive and anatomical variables collected prior to a large, multi-modal cognitive training study [25].",
"They include:",
"Demographic measures (i.e., age, sex, and education).",
"4 cognitive factors estimated via structural equation modeling [15].",
"Scores fro... | [] |
PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: Effect on cell survival and differentiation | Poly (ADP-ribose) polymerase (PARP) family members are ubiquitously expressed and play a key role in cellular processes, including DNA repair and cell death/survival balance. Accordingly, PARP inhibition is an emerging pharmacological strategy for cancer and neurodegenerative diseases. Consistent evidences support the ... | [
"BIOC"
] | [
"Neonatal hypoxic/ischemic encephalopathy",
"Oligodendrocyte precursor cells",
"PARP inhibitors",
"Remyelination"
] | [
"1307",
"1309"
] | [
"Oligodendrocytes, the cells wrapping the axons of the central nervous system (CNS) with the myelin sheath, derive from the oligodendrocyte precursor cells (OPCs) generated during development from multipotent neuroectodermal derivatives in the cortex and spinal cord (Bergles and Richardson, 2015).",
"These cells ... | [
"Oligodendrocyte precursor cell (OPC) were derived from fetal and adult neural stem cells.",
"PARP activity is much higher in fetal than adult—derived OPC.",
"PARP inhibition is toxic for fetal, but not adult OPC, also impairing OPC differentiation."
] |
Demographic hallmarks of an overbrowsed population state in American ginseng | Effects of high deer herbivory in North America on populations of favored plant browse species have been well-documented, however since less palatable plants now dominate the understory, we asked whether these species could be vulnerable as well, and if so, what symptoms might signal that this was occurring? Using Amer... | [
"AGRI",
"ENVI"
] | [
"Ginseng",
"Overbrowsing",
"Panax quinquefolius",
"Plant demography",
"Refugium"
] | [
"1105",
"2303",
"2309"
] | [
"“Since then I have lived to see state after state extirpate its wolves.",
"I have watched the face of many a newly wolfless mountain, and seen the south-facing slopes wrinkle with a maze of new deer trails.",
"I have seen every edible bush and seedling browsed, first to anemic desuetude, and then to death.”",
... | [] |
Construction of currency portfolios by means of an optimized investment strategy | This work focuses on the development of a technical breakout trading strategy based on the Donchian Channel approach, aiming to the construction of profitable portfolios. In this direction, the Modified Renko Bars (MRBs) were developed first; that proved to be a useful trading tool that responses more accurately than t... | [
"BUSI",
"DECI",
"MATH"
] | [
"Currencies",
"Investment strategy",
"Optimization algorithms",
"Profitable portfolios"
] | [
"1408",
"1803",
"2606",
"2613"
] | [
"The ultimate objective of any investor, trader or manager is to speculate, to generate profits in a consistent basis.",
"Simsek [27] assumed that any financial innovation on portfolio risks is likely to lead to speculation rather than risk sharing due to the motives of the participants in market.",
"An approac... | [
"Development of a new trading tool: the Modified Renko Bar (MRB).",
"We prove that the application of MRB in eight currency pairs increases the performance of channel breakout trading strategy by an average 30%.",
"Calibration of the parameters of the MRB channel strategy based on three optimization algorithms ... |
The future relevance of electricity balancing markets in Europe - A 2030 case study | In the context of an increasing share of variable renewable electricity in the European generation mix the question arises to what extent electricity balancing markets will gain importance in the future. On the one hand, forecast errors of variable renewable electricity drive demand for balancing. On the other hand, tr... | [
"ENER"
] | [
"Case study",
"Electricity balancing",
"Forecast error time series",
"Market analysis",
"Variable renewable electricity"
] | [
"2101"
] | [
"The increasing share of renewable electricity (RES-E) deployment required to reach the sustainability targets stated by the European Union will have increasing impacts on the functioning of electricity markets across all Member States.",
"The envisaged transformation is likely to require numerous regulatory adju... | [
"Development of amount and composition of electricity imbalances by 2030.",
"Assessment of the future relevance of electricity balancing markets in Europe.",
"Market revenues from balancing markets for different technologies."
] |
Hyperglycemia induced damage to mitochondrial respiration in renal mesangial and tubular cells: Implications for diabetic nephropathy | Damage to renal tubular and mesangial cells is central to the development of diabetic nephropathy (DN), a complication of diabetes which can lead to renal failure. Mitochondria are the site of cellular respiration and produce energy in the form of ATP via oxidative phosphorylation, and mitochondrial dysfunction has bee... | [
"BIOC",
"CHEM"
] | [
"Cellular bioenergetics",
"Diabetes",
"Mesangial cells",
"Mitochondrial dysfunction",
"Renal cells",
"Tubular cells"
] | [
"1308",
"1605"
] | [
"Diabetic nephropathy (DN) is a kidney disease which affects approximately one-third of patients with diabetes and develops over a long period of clinical silence [1].",
"Despite good metabolic control, patients with both Type 1 and Type 2 diabetes are at risk of DN [2–4].",
"With the epidemic rise in the incid... | [
"The kidney as an organ has high bioenergetic needs.",
"Cultured renal mesangial and tubular cells have different bioenergetic profiles.",
"Hyperglycemia had a toxic effect on renal cell mitochondrial metabolism.",
"Mesangial cells were more resistant to diabetes induced damage to cellular respiration than tu... |
FLBEIA: A simulation model to conduct Bio-Economic evaluation of fisheries management strategies | Fishery systems are complex systems that need to be managed in order to ensure a sustainable and efficient exploitation of marine resources. Traditionally, fisheries management has relied on biological models. However, in recent years the focus on mathematical models which incorporate economic and social aspects has in... | [
"COMP"
] | [
"Bio-economic model",
"Fisheries management",
"Fleet dynamics",
"Impact assessment",
"Management strategy evaluation"
] | [
"1706",
"1712"
] | [
"It describes fleet’s short term dynamics or tactical behaviour.",
"Each season it models how much effort is exerted and how it is distributed along metiers.6",
"In the first model, effort and its distribution along metiers are given as input data.",
"Thus the effort exerted by the fleet is independent of the... | [] |
Desmetramadol Has the Safety and Analgesic Profile of Tramadol Without Its Metabolic Liabilities: Consecutive Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Trials | Desmetramadol is an investigational analgesic consisting of (+) and (-) enantiomers of the tramadol metabolite O-desmethyltramadol (M1). Tramadol is racemic and exerts analgesia by monoaminergic effects of (-)-tramadol and (-)-M1, and by the opioid (+)-M1. Tramadol labeling indicates cytochrome P450 (CYP) isozyme 2D6 u... | [
"MEDI",
"NEUR"
] | [
"Desmetramadol",
"metabolism",
"poor metabolizer",
"tramadol",
"ultrarapid metabolizer"
] | [
"2703",
"2728",
"2808"
] | [
"The study design consisted of 2 consecutive randomized, double-blind, 3-period cross-over, placebo- and active comparator-controlled, single-center trials A and B performed between August 2014 and October 2014 and between October 2017 and December 2017 and conducted in a clinical research unit in Salt Lake City, U... | [
"Desmetramadol delivers the active metabolite of tramadol.",
"P450 enzyme inhibition made participants metabolically deficient.",
"Tramadol lost its analgesic efficacy in metabolically deficient participants.",
"Desmetramadol preserved its efficacy in metabolically deficient participants.",
"Desmetramadol a... |
Improved prediction of outcome in Parkinson's disease using radiomics analysis of longitudinal DAT SPECT images | No disease modifying therapies for Parkinson's disease (PD) have been found effective to date. To properly power clinical trials for discovery of such therapies, the ability to predict outcome in PD is critical, and there is a significant need for discovery of prognostic biomarkers of PD. Dopamine transporter (DAT) SPE... | [
"MEDI",
"NEUR"
] | [
"DAT SPECT",
"Longitudinal",
"Outcome prediction",
"Parkinson's disease",
"Radiomics",
"Textural features"
] | [
"2728",
"2741",
"2805",
"2808"
] | [
"Parkinson's disease (PD) is a progressive, degenerative movement disorder, characterized by neuronal loss in the substantia nigra with the loss of dopaminergic terminals in the basal ganglia (Brooks et al., 1990; Garnett et al., 1987; Stoessl et al., 2011).",
"Given the absence of proven disease modifying therap... | [
"Aim to enable image-assisted prediction of outcome in Parkinson's disease.",
"Radiomics analysis of clinical dopamine transporter (DAT) SPECT images (DaTscans).",
"Significant improvement in prediction of motor outcome."
] |
AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies | APS1/APECED patients are defined by defects in the autoimmune regulator (AIRE) that mediates central T cell tolerance to many self-antigens. AIRE deficiency also affects B cell tolerance, but this is incompletely understood. Here we show that most APS1/APECED patients displayed B cell autoreactivity toward unique sets ... | [
"BIOC"
] | [] | [
"1300"
] | [
"T lymphocyte tolerance is essential for limiting autoimmune disease.",
"Tolerance occurs “centrally” when developing thymocytes with strongly self-reactive T cell receptors (TCRs) are deleted following engagement of self-antigen-derived peptides presented by major histocompatibility complex (MHC) antigens.",
"... | [
"Each AIRE-deficient patient has a private repertoire of autoantibody reactivities",
"Loss of B cell tolerance occurs during T cell-dependent somatic hypermutation",
"Patient autoantibodies have unprecedented affinities for conformational epitopes",
"Patient autoantibodies can display disease-ameliorating pro... |
Low-cost touchscreen driven programmable dual syringe pump for life science applications | Syringe pumps are powerful tools able to automate routine laboratory practices that otherwise consume large amounts of manual labor time. Commercially available syringe pumps are expensive, difficult to customize, and often preset for a narrow range of operations. Here, we show how to build a programmable dual syringe ... | [
"ENGI",
"PHYS"
] | [
"3D printing",
"Cell homogenizer",
"Customization",
"Dual syringe pump",
"Plasmodium falciparum cell extract"
] | [
"2204",
"2205",
"2209",
"2210",
"3105"
] | [
"Syringe pumps have a wide variety of uses across fields from engineering to biology.",
"Their primary purpose is to continuously dispense precise volumes over a set amount of time.",
"They save time by running unsupervised and provide more consistency than human hands.",
"A dual syringe pump allows for two s... | [] |
Impact on demersal fish of a large-scale and deep sand extraction site with ecosystem-based landscaped sandbars | For the seaward harbour extension of the Port of Rotterdam in the Netherlands, approximately 220 million m3 sand was extracted between 2009 and 2013. In order to decrease the surface area of direct impact, the authorities permitted deep sand extraction, down to 20m below the seabed. Biological and physical impacts of l... | [
"AGRI",
"EART"
] | [
"Epifauna",
"Ground fish",
"Infauna",
"North Sea",
"Sand mining",
"Sediment"
] | [
"1104",
"1910"
] | [
"The demand for marine sand in the Netherlands and worldwide is strongly increasing.",
"In the Netherlands, approximately 24 million m3 sand is used annually for coastal nourishments and for construction.",
"An increase of annual coastline nourishments of up to 40-85 million m3 to counteract effects of future s... | [
"Demersal fish biomass in a deep sand extraction site increased 20-fold and fish species assemblage changed significantly.",
"The most abundant fish species in the extraction site is plaice whereas dab dominated reference areas.",
"Increased demersal fish biomass is closely linked to increased white furrow shel... |
Cerium oxide nanoparticles inhibit lipopolysaccharide induced MAP kinase/NF-kB mediated severe sepsis | The life threatening disease of sepsis is associated with high mortality. Septic patient survivability with currently available treatments has failed to improve. The purpose of this study was to evaluate whether lipopolysaccharide (LPS) induced sepsis mortality and associated hepatic dysfunction can be prevented by cer... | [
"MULT"
] | [
"Cerium oxide nanoparticles",
"LPS",
"MTT",
"Raw 264.7",
"Sepsis",
"Sprague Dawley rat"
] | [
"1000"
] | [
"This data articles contains data related to the research articles entitled “Inhibition of MAP kinase/NF-kB mediated signaling and attenuation of lipopolysaccharide induced severe sepsis by cerium oxide nanoparticles” in Biomaterials [1].",
"In the present study we have confirmed how the administration of a singl... | [] |
Numerical investigation of heat transfer enhancement in plate-fin heat sinks: Effect of flow direction and fillet profile | Many researchers have studied the thermal performance of heat sinks, however to the best knowledge of the authors, the effect of flow direction (place of fan) on the thermal performance of plate-fin heat sinks with fillet profile have not yet been investigated. In this paper, the investigation develops a computational ... | [
"CENG",
"ENGI"
] | [
"Computational fluid dynamic (CFD)",
"Fin",
"Heat sink",
"Thermal performance"
] | [
"1507",
"2201"
] | [
"Power density in electronic and microelectronic equipment is significantly increasing due to recent advances in semiconductor technology.",
"Therefore, in a highly competitive electronic equipment industry, the improvement of heat transfer rate for such devices is critically essential for long-term reliable oper... | [] |
Hyaluronidase activity in the salivary glands of tabanid flies | Tabanids are haematophagous insects that act as biological and mechanical vectors of various diseases, including viruses, bacteria and parasites. The saliva of these insects contains strong anticoagulant and vasodilatory activities as well as immunoregulatory peptides. Here we demonstrate pronounced hyaluronidase (hyas... | [
"AGRI",
"BIOC"
] | [
"Bloodfeeding",
"Hyaluronidase",
"Pathogen transmission",
"Saliva",
"Tabanids"
] | [
"1109",
"1303",
"1312"
] | [
"Tabanids (Diptera: Tabanidae) are a cosmopolitan group of haematophagous insects comprising more than 4.400 species (Roskov et al., 2015).",
"These pests are considered a serious nuisance, and are characterized by their persistent biting behavior and painful bites that may induce allergic reactions in sensitive ... | [
"Pronounced hyaluronidase activity was found in saliva of ten tabanid species studied.",
"Tabanid hyaluronidases cleave chondroitin sulfate and have pH optimum at 4.0 or 5.0.",
"The enzymes are monomers with estimated molecular weight between 35 and 52 kDa.",
"The high activity may correspond to the high effi... |
Optimal equipment deployment for biomass terminal operations | This paper investigates the optimization of biomass terminal equipment deployment. A mixed integer linear programming model is developed and applied to minimize the terminal's investment and operational costs related to dedicated and partially used or shared equipment between a terminal's operational steps. The results... | [
"BUSI",
"ENGI",
"SOCI"
] | [
"Biomass equipment",
"Biomass terminals",
"Equipment selection",
"MILP",
"Terminal logistics",
"Terminal operations"
] | [
"1403",
"2205",
"3313"
] | [
"Biomass use in the European Union (EU) is expected to significantly grow in the co-firing and heating sectors by 2030 (European Biomass Association, 2016).",
"At the moment, 4% of the total biomass used for energy purposes in the EU is imported (Dafnomilis et al., 2017).",
"However by 2030, this amount (both i... | [
"Optimization of biomass port terminal equipment is presented.",
"MILP model minimizes investment and operational costs in biomass bulk terminals.",
"Real data from industry used as input.",
"Results provide optimal equipment allocation and utilization, optimal terminal size and associated logistics.",
"Ins... |
MbT-Tool: An open-access tool based on Thermodynamic Electron Equivalents Model to obtain microbial-metabolic reactions to be used in biotechnological process | Modelling cellular metabolism is a strategic factor in investigating microbial behaviour and interactions, especially for bio-technological processes. A key factor for modelling microbial activity is the calculation of nutrient amounts and products generated as a result of the microbial metabolism. Representing metabol... | [
"BIOC",
"COMP"
] | [
"Energy-transfer-efficiency",
"MbT-Tool",
"Microbial metabolic reaction",
"Microbial metabolism",
"Microbial yield prediction",
"Thermodynamics"
] | [
"1303",
"1304",
"1305",
"1311",
"1315",
"1706"
] | [
"For the construction and development of models of living organisms, it is necessary to describe their physical constants, physiological reactions, interactions and responses to the environment.",
"A robust model of any living system must include chemicals and conservation principles, and relate stoichiometric ma... | [
"Represent microbial metabolism based on thermodynamics.",
"Write microbial metabolic reactions to represent environmental processes.",
"An open-source computational tool to study microbial activity",
"The basis of metabolic behaviour-rules embedded in an individual-based model."
] |
Connectome analysis with diffusion MRI in idiopathic Parkinson's disease: Evaluation using multi-shell, multi-tissue, constrained spherical deconvolution | Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects extensive regions of the central nervous system. In this work, we evaluated the structural connectome of patients with PD, as mapped by diffusion-weighted MRI tractography and a multi-shell, multi-tissue (MSMT) constrained spherical decon... | [
"MEDI",
"NEUR"
] | [
"Connectome",
"Diffusion MRI",
"Diffusion tensor imaging",
"Lewy bodies",
"Neurodegenerative disorders",
"Support vector machine"
] | [
"2728",
"2741",
"2805",
"2808"
] | [
"Parkinson's disease (PD) is the second most common neurological disorder after Alzheimer's disease, affecting 6 million individuals worldwide (Vos et al., 2016).",
"The disease is characterized by motor symptoms (i.e., akinesia or bradykinesia, rigidity, and tremor) as well as non-motor symptoms such as cognitiv... | [
"Connectomes mapped in Parkinson's disease (PD) using multi-shell tractography.",
"Multi-shell tractography provided improved sensitivity to connectome pathology.",
"Machine learning accurately predicted PD diagnosis based on connectome.",
"Connectome pathology in PD was localized to basal ganglia-thalamocort... |
Onset of deaminase APOBEC3B induction in response to DNA double-strand breaks | Deamination of 5-methyl cytosine is a major cause of cancer-driver mutations in inflammation-associated cancers. The deaminase APOBEC3B is expressed in these cancers and causes mutations under replication stress; however, the mechanisms by which APOBEC3B mediates deamination and its association with genomic disorders a... | [
"BIOC"
] | [
"APOBEC3B",
"Ataxia-telangiectasia and Rad3-related",
"Base excision repair",
"Deaminase",
"Genomic instability",
"Uracil-DNA glycosylase"
] | [
"1303",
"1304",
"1307",
"1312"
] | [
"Cancer development is associated with mutations and genomic instability [1,2].",
"In cancers that develop under conditions of chronic inflammation, deamination-associated C>T mutations are induced massively in association with expression of deaminase APOBEC3A and B [3].",
"These C>T mutations occur widely in e... | [
"APOBEC3B is stabilized to induce deamination reaction in response to DSBs.",
"Deamination leads to formation of late-onset DSBs through UNG2-mediated BER.",
"Late-onset DSBs induced in an ATR-dependent manner are persistent."
] |
Urban Big Data and the Development of City Intelligence | This study provides a definition for urban big data while exploring its features and applications of China's city intelligence. The differences between city intelligence in China and the “smart city” concept in other countries are compared to highlight and contrast the unique definition and model for China's city intel... | [
"CENG",
"COMP",
"ENER",
"ENGI",
"ENVI",
"MATE"
] | [
"City intelligence",
"Construction emphases",
"Ternary space",
"Urban big data"
] | [
"1500",
"1700",
"2102",
"2200",
"2305",
"2501"
] | [
"Amid China's rapid industrialization and urbanization, the rise in the population, manufacturing, and traffic of its cities is becoming increasingly intense and complex leading to a variety of urban diseases such as rapid population growth, traffic jams, environmental deterioration, housing shortages, employment p... | [] |
An Internet of Energy Things Based on Wireless LPWAN | Under intense environmental pressure, the global energy sector is promoting the integration of renewable energy into interconnected energy systems. The demand-side management (DSM) of energy systems has drawn considerable industrial and academic attention in attempts to form new flexibilities to respond to variations i... | [
"CENG",
"COMP",
"ENER",
"ENGI",
"ENVI",
"MATE"
] | [
"Demand-side management",
"Internet of Things",
"LoRa technology",
"Low-power wide-area network",
"Narrow-band Internet of Things"
] | [
"1500",
"1700",
"2102",
"2200",
"2305",
"2501"
] | [
"Under intense environmental pressure, the global energy sector is transitioning toward clean and sustainable development.",
"The concept of the smart grid has been widely accepted in the last decade as a means of integrating higher percentages of renewables [1,2].",
"In 2016, China’s government announced new p... | [] |
Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity | We analyzed genome-wide association studies (GWASs), including data from 71,638 individuals from four ancestries, for estimated glomerular filtration rate (eGFR), a measure of kidney function used to define chronic kidney disease (CKD). We identified 20 loci attaining genome-wide-significant evidence of association (p ... | [
"BIOC",
"MEDI"
] | [] | [
"1311",
"2716"
] | [
"Chronic kidney disease (CKD) is a major public health burden and affects nearly 10% of the global population.1",
"Reduced estimated glomerular filtration rate (eGFR), a measure of kidney function used to define CKD, is associated with premature cardiovascular disease and mortality, acute kidney injury, and progr... | [] |
Towards on-farm pig face recognition using convolutional neural networks | Identification of individual livestock such as pigs and cows has become a pressing issue in recent years as intensification practices continue to be adopted and precise objective measurements are required (e.g. weight). Current best practice involves the use of RFID tags which are time-consuming for the farmer and dist... | [
"COMP",
"ENGI"
] | [
"Biometrics",
"Convolutional neural network",
"Deep learning",
"Pig face recognition"
] | [
"1700",
"2200"
] | [
"The need for on farm identification of individual animals has become more pressing in recent years as sustainable intensification has become commonplace, and the ability to monitor inputs to, and outputs of each animal is increasingly desired.",
"The major method of livestock identification is via passive Radio ... | [
"Face recognition for humans is a well-studied and proven biometric.",
"Precision agriculture requires individual animals to be identified reliably.",
"Current methods e.g. RFID have shortcomings (range, distressing to fit).",
"We adapt approaches from human literature to on farm pig-face recognition.",
"Ac... |
Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial | Background: The achievement of glycaemic control remains challenging for patients with type 1 diabetes. We assessed the effectiveness of day-and-night hybrid closed-loop insulin delivery compared with sensor-augmented pump therapy in people with suboptimally controlled type 1 diabetes aged 6 years and older. Methods: I... | [
"MEDI"
] | [] | [
"2700"
] | [
"Type 1 diabetes represents 5–10% of cases with diabetes worldwide, and is presently incurable.1",
"Achievement of recommended glycaemic control remains challenging across all age groups,2 in part because tight glycaemic control increases the risk of hypoglycaemia.3,4",
"Over the past decade, considerable progr... | [] |
T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage | Objective: To investigate the potential of quantitative susceptibility mapping (QSM) and T2* relaxation time mapping to determine mechanical and structural properties of articular cartilage via univariate and multivariate analysis. Methods: Samples were obtained from a cartilage repair study, in which surgically induce... | [
"ENGI",
"MEDI"
] | [
"Articular cartilage",
"Post-traumatic osteoarthritis",
"Quantitative susceptibility mapping",
"T2* relaxation"
] | [
"2204",
"2732",
"2745"
] | [
"Osteoarthritis (OA) is a progressive disease that leads to restricted mobility and severe joint pain1,2.",
"The onset of OA may be due to joint trauma, such as a ligamental tear or focal cartilage loss.2",
"Magnetic resonance imaging (MRI) is among the best non-invasive tools available for diagnosis of OA.",
... | [] |
Magnetic properties of a LuVO3 single crystal studied by magnetometry, heat capacity and neutron diffraction | We have studied the magnetic properties of a LuVO3 single crystal. The compound shows an orbital ordering at TOO = 179 K followed by the antiferromagnetic spin ordering at TSO = 109 K. In the magnetically ordered regime, there appears an abrupt change at To = 82.5 K in the magnetisation, indicating a first-order transi... | [
"MATE"
] | [
"Antiferromagnets",
"Disorder materials",
"Heat capacity",
"Magnetic materials",
"Spin orbital order"
] | [
"2501",
"2502",
"2503",
"2504"
] | [
"The interplay between spin-orbital interaction and phase transitions has attracted much interest recently in strongly correlated electron systems, in particular the transition metal (TM) oxides.",
"Coupling to the lattice further enriches the interplay through lattice distortions, phonons, and cooperative effect... | [] |
Evolution and functional classification of mammalian copper amine oxidases | Mammalian copper-containing amine oxidases (CAOs), encoded by four genes (AOC1-4) and catalyzing the oxidation of primary amines to aldehydes, regulate many biological processes and are linked to various diseases including inflammatory conditions and histamine intolerance. Despite the known differences in their substra... | [
"AGRI",
"BIOC"
] | [
"Active site motif",
"Copper amine oxidase",
"Functional classification",
"Phylogenetics",
"Three-dimensional structure"
] | [
"1105",
"1311",
"1312"
] | [
"Copper-containing amine oxidases (CAOs) are a large class of enzymes that catalyze the oxidation of primary amines to the corresponding aldehyde associated with the reduction of molecular oxygen to hydrogen peroxide (Reviewed in Klema and Wilmot, 2012).",
"Because of their wide distribution in mammalian tissues,... | [
"Active site motif classifies CAOs to functional sub-families.",
"Variable residues from the active site motif contribute to substrate selectivity.",
"One sub-family specific residue seems to be important for substrate preference.",
"Expression profile of mammalian AOC1, AOC2, AOC3 and AOC4 is species-specifi... |
Data for the level of women׳s self-esteem and couples’ sexual satisfaction before and after mammoplasty | Nowadays, one of the existing problems in the societies is the increase in the rate of plastic surgeries such as mammaplasty, especially among the women in Iran. The present study was conducted on the positive and negative effects of this surgery on Iranian women׳s self-esteem and couples’ sexual satisfaction before an... | [
"MULT"
] | [
"Mammaplasty",
"Self–esteem",
"Sexual satisfaction",
"Women"
] | [
"1000"
] | [
"Out of 100 investigated couples, 3% of the women were under 20 years of age, 17% between 20–30 years, 49% between 30–40 years and 31% over age of 40.",
"About 57% of their spouses were employees and 43% were self-employed.",
"About 19% of the couples had no children, 19% had one child, 55% had two children and... | [] |
Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function | Fetal cardiomyocyte adaptation to low levels of oxygen in utero is incompletely understood, and is of interest as hypoxia tolerance is lost after birth, leading to vulnerability of adult cardiomyocytes. It is known that cardiac mitochondrial morphology, number and function change significantly following birth, although... | [
"BIOC",
"MEDI"
] | [
"Cardiac",
"Hypoxia",
"Mitochondria",
"Mitofusin",
"Neonatal"
] | [
"1312",
"2705"
] | [
"Fetal cardiomyocytes are adapted to function in low levels of oxygen in utero, whereas adult cardiomyocytes are extremely vulnerable to hypoxia, as evidenced by high rates of mortality and morbidity caused by ischemic heart disease [1].",
"Shortly after birth, cardiomyocytes lose their capability to adapt to hyp... | [
"The reduction in HIF signaling encountered by the heart following birth acts as a physiological switch.",
"Reduced postnatal cardiac HIF signaling affects mitochondrial number, structure and function.",
"Experimental study of mitochondria is prone to artifacts due to the effect of oxygen.",
"Cardiomyocytes e... |
Enhanced case management can be delivered for patients with EVD in Africa: Experience from a UK military Ebola treatment centre in Sierra Leone | Background: Limited data exist describing supportive care management, laboratory abnormalities and outcomes in patients with Ebola virus disease (EVD) in West Africa. We report data which constitute the first description of the provision of enhanced EVD case management protocols in a West African setting. Methods: Demo... | [
"MEDI"
] | [
"Critical care",
"Early warning score",
"Ebola virus disease",
"Viral haemorrhagic fever"
] | [
"2725",
"2726"
] | [
"The recent outbreak of Ebola virus disease (EVD) in West Africa was unprecedented.",
"Following the first case in Guinea in December 2013, 28 616 cases were reported in Guinea, Liberia and Sierra Leone resulting in 11 310 deaths.1,2",
"Fragile healthcare systems in the affected countries struggled to cope with... | [
"EVD is associated with life-threatening electrolyte imbalance and organ dysfunction.",
"Clinical staging/early warning scores can be useful EVD prognostic indicators.",
"Enhanced protocolized care is a blueprint for future treatment in low-resource settings."
] |
A generalised framework for saliency-based point feature detection | Here we present a novel, histogram-based salient point feature detector that may naturally be applied to both images and 3D data. Existing point feature detectors are often modality specific, with 2D and 3D feature detectors typically constructed in separate ways. As such, their applicability in a 2D-3D context is very... | [
"COMP"
] | [
"2D-3D registration",
"Feature detection",
"Feature matching",
"Point detection",
"Saliency"
] | [
"1707",
"1711",
"1712"
] | [
"Light Detection And Ranging (LiDAR) scanners have been used to obtain 3D data for decades, but it is only in recent years that they have seen more widespread applicability due to the high computational capacity required to cope with such large datasets.",
"However, the integration of LiDAR scans with data from o... | [
"A novel multi-modal histogram-based salient point detector is proposed.",
"The general formulation allows salient point detection in both images and 3D data.",
"The derivative-based approach improves upon existing intensity based 2D approaches.",
"The 3D detector naturally operates on both the geometry and t... |
Regional scale hydrologic modeling of a karst-dominant geomorphology: The case study of the Island of Crete | Crete Island (Greece) is a karst dominated region that faces limited water supply and increased seasonal demand, especially during summer for agricultural and touristic uses. In addition, due to the mountainous terrain, interbasin water transfer is very limited. The resulting water imbalance requires a correct quantifi... | [
"ENVI"
] | [
"Crete",
"Karst",
"Mediterranean",
"Multi-site calibration",
"SWAT",
"Water balance"
] | [
"2312"
] | [
"“Karst” identifies a specific geological landscape and morphology formed by the dissolving action of water on soluble carbonate rocks such as primarily limestone, but also marble, dolomite, and gypsum.",
"These rocks are mechanically strong but chemically soluble with high degree of secondary porosity.",
"As a... | [
"SWAT model was adapted and integrated with a karst-flow model (KSWAT model).",
"KSWAT has allowed calibrating 22 streamflow and 47 springs gauging stations.",
"KSWAT has captured the spatial and temporal variability of water balance.",
"The proposed methodology has allowed defining the karst recharge area of... |
Aligning carbon targets for construction with (inter)national climate change mitigation commitments | In the face of a changing climate, a growing number of construction firms are adopting carbon reduction targets on individual projects and across their portfolios. In the wake of the Paris Agreement, some firms are seeking a means of aligning their targets with sectoral, national and international mitigation commitment... | [
"ENGI"
] | [
"Buildings",
"Climate change mitigation",
"Construction",
"Embodied carbon",
"Paris Agreement",
"Science Based Targets",
"Whole life carbon"
] | [
"2205",
"2208",
"2210",
"2215"
] | [
"The dangers posed by anthropogenic carbon emissions and a changing climate are well documented [1], yet in 2016 humanity emitted a further 36 GtCO2 from fossil fuels and industrial processes [2].",
"In December 2015, 195 countries adopted the first legally binding global climate deal seeking to hold increases in... | [
"Some firms are trying to align carbon targets with (inter)national mitigation commitments.",
"Construction firms face a unique set of challenges in aligning targets.",
"There are a range of approaches, each with distinct limitations.",
"Adopting different approaches yields different targets and corresponding... |
Influence of adenovirus and MVA vaccines on the breadth and hierarchy of T cell responses | Viral-vectored vaccines are in clinical development for several infectious diseases where T-cell responses can mediate protection, and responses to sub-dominant epitopes is needed. Little is known about the influence of MVA or adenoviral vectors on the hierarchy of the dominant and sub-dominant T-cell epitopes. We inve... | [
"BIOC",
"IMMU",
"MEDI",
"VETE"
] | [
"Subdominant T-cell epitopes",
"T-cell hierarchy",
"Vaccines",
"Viral vectors"
] | [
"1313",
"2400",
"2725",
"2739",
"3400"
] | [
"Leading vaccine strategies aiming at inducing strong cellular immunity in humans use recombinant adenovirus (Ad) and Modified Vaccinia Ankara (MVA) [1,2].",
"These vectors have been assessed since the late 90s for their capacity to induce different frequency, phenotype, function and localization of T- and B-cell... | [
"Viral-vectored vaccines are expected to induce T-cell responses to sub-dominant epitopes.",
"Hierarchy of T-cell response is influenced by the timing of analysis after a single immunization.",
"Repeated homologous immunization reduces the breadth of T-cell response.",
"Heterologous prime-boost induces a mode... |
Decreased Serum Sirtuin-1 in COPD | Background The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in patients with COPD. Methods Serum SIRT1 protein of all samples was measu... | [
"MEDI"
] | [
"COPD",
"biomarker",
"emphysema",
"serum",
"sirtuin-1"
] | [
"2705",
"2706",
"2740"
] | [
"Commercially available reagents were obtained as follows: Roswell Park Memorial Institute medium (RPMI) medium 1640 (RPMI 1640) (No. 32404-014) and Dulbecco's Modified Eagle Medium (DMEM) (31053-028) were obtained from Life Technologies; fetal bovine serum (FBS), complete protease inhibitor cocktail (11836153001),... | [] |
Making progress in early breast cancer: Taking time or accepting risk? | Outcomes for patients diagnosed with early breast cancer in developed countries have improved substantially over recent decades. Adjuvant therapies have contributed to this improvement and their benefits have been confirmed in large randomised controlled trials (RCTs) and meta-analyses. Lower event rates, whilst welcom... | [
"BIOC",
"MEDI"
] | [
"Breast cancer",
"Clinical trials",
"Observational studies",
"Randomised trials",
"Surrogate markers"
] | [
"1306",
"2730"
] | [
"Frustration at the slow rate of progress in trying to develop and improve treatments for early breast cancer is commonly expressed by both patient and medical communities.",
"There is an obvious tension between the desire for improved treatments and other technologies and the need for careful evaluation.",
"Th... | [
"Surrogate markers are yet to be developed and validated in early breast cancer.",
"Reliance on observational data to evaluate treatment effects is risky.",
"Prospective randomised trials are difficult but remain vital to progress.",
"Research approval processes need simplification and streamlining."
] |
Rapid, cost-effective and accurate quantification of Yucca schidigera Roezl. steroidal saponins using HPLC-ELSD method | Yucca GRAS-labelled saponins have been and are increasingly used in food/feed, pharmaceutical or cosmetic industries. Existing techniques presently used for Yucca steroidal saponin quantification remain either inaccurate and misleading or accurate but time consuming and cost prohibitive. The method reported here addres... | [
"AGRI",
"CHEM"
] | [
"Adulteration",
"HPLC-ELSD",
"Quantification",
"Quillaja",
"Saponin",
"Steroidal saponin",
"Yucca",
"Yucca brevifolia",
"Yucca schidigera"
] | [
"1106",
"1602"
] | [
"Well before their chemical structures were elucidated, Yucca saponins were utilised by American Indians in a series of applications, including soap.",
"Multiple uses of a range of compounds originate from different parts of 35–40 Yucca (Agavaceae) species.",
"Yucca are mainly distributed in the deserts of Cent... | [
"Yucca steroidal saponins are widely used in food/feed industries.",
"HPLC/ELSD is a new technique for measurement of Yucca steroidal saponins.",
"Contrary to classical techniques, HPLC/ELSD is rapid, accurate and reliable method.",
"HPLC/ELSD is a time- and cost-effective technique suitable for routine analy... |
Synthesis, characterization and visible light photocatalytic activity of metal based TiO2 monoliths for CO2 reduction | The use of multichannel monoliths for CO2 photoreduction applications is gaining increased attention over slurry and annular reactors due to their tunable geometry for reactor designs and exposed surface area per volume. Metal based TiO2 sol with varying concentrations of Cr, V and Co were deposited on ceramic honeycom... | [
"CENG",
"CHEM",
"ENGI",
"ENVI"
] | [
"CO2 reduction",
"Ceramic monoliths",
"Optical fibres",
"Photocatalysis",
"Titanium dioxide",
"Visible light"
] | [
"1500",
"1600",
"2209",
"2304"
] | [
"The continuous combustion of fossil fuels and depletion of existing resources are intensifying the research and development of alternative future energy options that can directly abate and process ever-increasing carbon dioxide (CO2) emissions.",
"Over the past decade, titanium dioxide (TiO2) has been considered... | [
"Coated monolithic structures were tested for visible-light-induced CO2 reduction.",
"Red shift in absorption edge was observed with increasing metal concentration.",
"Fuel production rate is enhanced upon chromium, vanadium or cobalt deposition."
] |
Dynamic patterns of overexploitation in fisheries | Understanding overfishing and regulating fishing quotas is a major global challenge for the 21st Century both in terms of providing food for humankind and to preserve the oceans’ ecosystems. However, fishing is a complex economic activity, affected not just by overfishing but also by such factors as pollution, technolo... | [
"ENVI"
] | [
"Fisheries",
"Lotka-Volterra",
"Overfishing",
"System dynamic"
] | [
"2302"
] | [
"Many of the world’s fisheries are showing a decline in the fishing yield, a phenomenon that’s clearly important for the global economy and which is often interpreted in terms of the overexploitation of the fish stock (Pauly, 2009): the fishing industry is consistently depleting the fish stock at a rate higher than... | [
"For the first time, the “predator-prey” model is used for the quantitative description of an economic predatory dynamic in real-world fisheries.",
"A simple “mind-sized” model highlights the driving forces that lead to the resources’ overexploitation and the collapse of a production system.",
"A renewable fish... |
“Nordic Cool” and writing system mimicry in global linguistic landscapes | Fuelled by political and economic trends in the 21st century, the concepts “New Nordic” and “Nordic Cool” have entered the global scene in design, cuisine, entertainment, and general lifestyle (Østergaard et al., 2014; Skou and Munch, 2016; Andersen et al., 2019). Simultaneously, due to globalisation, individuals today... | [
"ARTS",
"SOCI"
] | [
"Globalese",
"Globalisation",
"Indexicality",
"Linguistic landscape",
"Writing system mimicry"
] | [
"1203",
"3310"
] | [
"The term linguistic landscape, which refers to the visibility of languages in public spaces, was first introduced to linguistics by Landry and Bourhis in 1997.",
"In their study, the linguistic landscape of an area is defined by the languages on public road signs, advertisements, and commercial shop signs (Landr... | [
"Positive associations relating to the Nordics increase visibility of Nordic linguistic features.",
"International brands use Nordic linguistic features to evoke positive associations in consumers.",
"Nordic graphemes may be used as innovative features in globalese.",
"The graphemes 〈Ø〉 and 〈Å〉 are particular... |
Chitinozoan biozonation in the upper Katian and Hirnantian of the Welsh Basin, UK | Here we present a chitinozoan biostratigraphical framework for the South Wales upper Katian and Hirnantian (Ashgill) succession. The current study indicates that three of the six Avalonian Ashgill chitinozoan biozones are recognised in the Welsh Basin; the bergstroemi, fossensis and umbilicata biozones. The Baltoscandi... | [
"AGRI",
"EART"
] | [
"Avalonia",
"Chitinozoan",
"Hirnantian",
"Katian",
"Ordovician",
"Welsh Basin"
] | [
"1105",
"1911"
] | [
"The recent development of an integrated Upper Ordovician chitinozoan biozonation in British Avalonia (Vandenbroucke and Vanmeirhaeghe, 2007; Vandenbroucke, 2008a), based on type areas for the British chronostratigraphical scheme (Fortey et al., 1995, 2000), recognises six chitinozoan biozones with two subzones for... | [
"A new composite Katian-Hirnantian chitinozoan biozonation for the Welsh Basin, UK.",
"Three new species of chitinozoan are defined.",
"The Welsh Basin chitinozoan assemblage implies Laurentian-Avalonian faunal links.",
"Belonchitina cf. gamachiana occurs in the anceps Biozone."
] |
Association of open-angle glaucoma loci with incident glaucoma in the blue mountains eye study | Purpose To determine if open-angle glaucoma (OAG)-associated single nucleotide polymorphisms (SNPs) are associated with incident glaucoma and if such genetic information is useful in OAG risk prediction. Design Case-control from within a population-based longitudinal study. Methods study population: Individuals aged ov... | [
"MEDI"
] | [] | [
"2731"
] | [
"The Blue Mountains Eye Study was approved by the Human Research Ethics Committee of the University of Sydney for investigation of the epidemiology and genetics of ocular disease.",
"The BMES has been described previously.10",
"Briefly, the BMES is a population-based study of individuals living in the Blue Moun... | [] |
Data on endogenous chicken sperm peptides and small proteins obtained through Top-Down High Resolution Mass Spectrometry | The endogenous peptides and small proteins present in chicken sperm were identified in the context of the characterization of a fertility-diagnostic method based on the use of ICM-MS (Intact Cell Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry). The interpretation and description of these d... | [
"MULT"
] | [
"Chicken",
"Peptidome",
"Sperm",
"Top-Down HRMS"
] | [
"1000"
] | [
"This dataset consists of a compendium of peptidoforms and small proteoforms extracted from chicken ejaculated sperm, that were pre-fractionated using gel filtration or reverse phase chromatography and identified through a Top-Down mass spectrometry analysis.",
"Hence, this set includes data regarding the identit... | [] |
Cognitive impairment is independently associated with mortality, extended hospital stays and early readmission of older people with emergency hospital admissions: A retrospective cohort study | Background: Older adults admitted to hospital are often cognitively impaired. It is not clear whether the presence of cognitive impairment conveys an additional risk for poor hospital outcomes in this patient population. Objectives: To determine whether cognitive impairment in hospitalised older adults is independently... | [
"NURS"
] | [
"Cognitive impairments",
"Dementia",
"Hospitalization",
"Length of stay",
"Mortality",
"Older adults",
"Patient readmission"
] | [
"2900"
] | [
"Emergency hospital admissions of older people are increasing globally, and are likely to continue to rise given current demographic trends.",
"Older adults now comprise around two-thirds of hospital inpatients, and up to 50% of these patients have some form of cognitive impairment, including that related to deme... | [] |
Ion-irradiation-induced clustering in W-Re and W-Re-Os alloys: A comparative study using atom probe tomography and nanoindentation measurements | This study examines clustering and hardening in W-2 at.% Re and W-1 at.% Re-1 at.% Os alloys induced by 2 MeV W+ ion irradiation at 573 and 773 K. Such clusters are known precursors to the formation of embrittling precipitates, a potentially life-limiting phenomenon in the operation of fusion reactor components. Increa... | [
"MATE"
] | [
"Atom probe tomography",
"Ion irradiation",
"Nanoindentation",
"Nuclear fusion",
"Tungsten rhenium osmium alloys"
] | [
"2503",
"2504",
"2506",
"2507"
] | [
"Tungsten is the prime candidate for plasma facing applications in future nuclear fusion reactors, being one of only a handful of materials that are capable of withstanding the harsh operating conditions of up to ∼1300 K, power densities of 1–20 MW m−2 and irradiation from both 14 MeV neutrons and 2 MeV alpha parti... | [] |
Digital platforms and the changing nature of physical work: Insights from ride-hailing | The rise of digital platforms has enabled new forms of work, but the nature of these new forms, particularly the role of the digital platform in shaping work relations, is not well understood. This study explores how the presence of the digital platform manifests itself in workers’ perceptions of their work in the cont... | [
"COMP",
"SOCI"
] | [
"Digital platform",
"Digitalization",
"Gig economy",
"Lyft",
"Platform economy",
"Ride-hailing",
"Sharing economy",
"Taxi",
"Uber",
"Work"
] | [
"1705",
"1710",
"3309"
] | [
"Digital platforms such as Amazon MTurk, Uber, and AirBnB have enabled the emergence of various new forms of work (Colbert, Yee, & George, 2016; Gandini, 2019; Howcroft & Bergvall-Kåreborn, 2019; Kuhn & Maleki, 2017).",
"In the context of platform-enabled work, we define a digital platform as the digital infrastr... | [
"We identify six key mechanisms of platform-enabled work, namely self-employment, time management, income, information control, pricing, and rating.",
"From workers’ perspective, flexibility in work relationships is a key positive element of platform-enabled work.",
"The stark power disparity between workers an... |
Neurocognitive evidence for mental imagery-driven hypoalgesic and hyperalgesic pain regulation | Mental imagery has the potential to influence perception by directly altering sensory, cognitive, and affective brain activity associated with imagined content. While it is well established that mental imagery can both exacerbate and alleviate acute and chronic pain, it is currently unknown how imagery mechanisms regul... | [
"NEUR"
] | [] | [
"2805",
"2808"
] | [
"Mental imagery – the ability to generate internal representations that preserve the core features of a perceptual experience – relies on similar neural mechanisms as those of actual perception (Kosslyn et al., 2001; McNorgan, 2012).",
"This mechanism of shared representation between imagery and perception is com... | [
"Specific mental imagery contents bias pain perception towards hypoalgesic and hyperalgesic outcomes",
"Mental imagery influences pain-related perceptual decision-making in terms of stimulus discriminability and response bias",
"Pain-related N2 amplitudes are modulated by mental-imagery content",
"Cortical ac... |
The dataset of methylglyoxal activating p38 and p44/42 pathway in osteoclast | Diabetes mellitus (DM) is a kind of chronic metabolic disease that could be characterized by uncontrollable high blood glucose (hyperglycemia) over a prolonged period and diverse complications in various organs. These complications include activation of stress responses in bone such as oxidative stress and inflammation... | [
"MULT"
] | [
"Diabetes",
"Methylglyoxal",
"Osteoclast",
"Osteoporosis",
"Pathways"
] | [
"1000"
] | [
"The band densities quantification of Western Blotting was shown in the graph below.",
"In Fig. 1a, Representative blots of p-p38, p-p44/42, p44/42, and beta-actin of the cells after exposing to MG (400 μM) after the treatment time intervals between 1 h and 24 h. Phosphorylation of p38 and p44/42 were induced by ... | [] |
Economic impacts of climate change and climate change adaptation strategies in Vanuatu and Timor-Leste | The fisheries sectors in Vanuatu and Timor-Leste are important sources of food and income. Similar to other developing countries and those in the Pacific, they are vulnerable to the impacts of climate change more so because of their geographic location, socioeconomic conditions and political instability. Nonetheless, t... | [
"AGRI",
"ECON",
"ENVI",
"SOCI"
] | [
"Aquaculture",
"Economic modeling",
"Fish aggregating devices",
"Natural resource management",
"Timor-Leste",
"Vanuatu"
] | [
"1104",
"2002",
"2300",
"2308",
"3308"
] | [
"Throughout the tropical Pacific where the majority of rural people still live and depend on subsistence agriculture, the fisheries sector (including aquaculture) is vital to economic development, livelihood, and food and nutrition security.",
"Vanuatu has a long tradition tied to inshore and offshore fisheries; ... | [
"Analyzed economic impact of adaptation strategies in Vanuatu and Timor-Leste.",
"Strategies: aquaculture, natural resource management, and inshore fish aggregating devices.",
"Positive impact of strategies, but current scales of adaptation are too small.",
"Need aggressive, but judicious, increases in invest... |
Dissecting peak broadening in chromatography columns under non-binding conditions | Peak broadening in small columns is dominated by spreading in the extra column volume and not by hydrodynamic dispersion or mass transfer resistances. Computational fluid dynamics (CFD) permits to study the influence of these effects separately. Here, peak broadening of three single component solutes – silica nanoparti... | [
"BIOC",
"CHEM"
] | [
"Computational fluid dynamics",
"Extra column volume",
"Film mass transfer",
"Hydrodynamic dispersion",
"Mass transfer mechanism",
"Peak broadening effects",
"Pore diffusion",
"Scalability"
] | [
"1303",
"1602",
"1605"
] | [
"Peak broadening under non-binding conditions is caused by extra column dispersion, hydrodynamic dispersion in the column and mass transfer resistances [1].",
"The (relative) contribution of these mechanisms varies at different scales.",
"For instance, in process development, virus clearance studies and explora... | [
"Mass transfer coupled computational fluid dynamics model is used to analyze columns.",
"Peak broadening mechanisms incl. extra column effects are quantitatively assessed.",
"Band broadening under non-binding condition is accurately predicted across scales."
] |
Cell-cell fusion in the nervous system: Alternative mechanisms of development, injury, and repair | Over a century ago, the seminal work of Ramón y Cajal revealed that the nervous system is made of individual units, the neurons, which are related to each other by contiguity rather than continuity. This view overturned the idea that the nervous system was a reticulum of fibers, a rete diffusa nervosa, as proposed and ... | [
"BIOC"
] | [
"Axonal regeneration",
"Cell-cell fusion",
"Dendrite remodelling",
"Fusogen",
"Heterokaryon",
"Neuron theory"
] | [
"1307",
"1309"
] | [
"The neuron theory proposed by Ramón y Cajal, according to which neurons exist as individual cells, has been the foundation of modern neuroscience and has paved the way for our current understanding of how the nervous system develops and functions.",
"Neurons are highly polarized cells that extend two functionall... | [
"The neuron theory of Ramón y Cajal states that neurons are individual cells.",
"Despite the neuron theory, neurons and glia are able to fuse their plasma membranes.",
"Some neurons undergo self-fusion during development and repair.",
"Neurons and glia are able to form multinucleated cells."
] |
Differentiation of liver progenitor cell line to functional organotypic cultures in 3D nanofibrillar cellulose and hyaluronan-gelatin hydrogels | Physiologically relevant hepatic cell culture models must be based on three-dimensional (3D) culture of human cells. However, liver cells are generally cultured in two-dimensional (2D) format that deviates from the normal in vivo morphology. We generated 3D culture environment for HepaRG liver progenitor cells using wo... | [
"BIOC",
"CENG",
"ENGI",
"MATE"
] | [
"3D Cell culture",
"Cell differentiation",
"Hepatocyte",
"Multicellular spheroids",
"Nanocellulose",
"Organotypic"
] | [
"1304",
"1502",
"2211",
"2502",
"2503"
] | [
"Pharmaceutical industry, regulatory authorities, and academic investigators need liver cell cultures to predict and estimate metabolism, excretion and toxicity of drugs and other chemicals in the human liver.",
"Due to the inter-species differences animals and animal cells lead frequently to misleading, and some... | [] |
Emerging therapies for the treatment of skeletal muscle wasting in chronic obstructive pulmonary disease | Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that constitutes a major global health burden. A significant proportion of patients experience skeletal muscle wasting and loss of strength as a comorbidity of their COPD, a condition that severely impacts on their quality of life and survival. ... | [
"MEDI",
"PHAR"
] | [
"Chronic obstructive pulmonary disease (COPD)",
"Comorbidities",
"Pulmonary rehabilitation",
"Skeletal muscle",
"Therapeutic strategies",
"Wasting"
] | [
"2736",
"3004"
] | [
"Chronic obstructive pulmonary disease (COPD) is a progressive lung disease caused by excessive inflammation leading to irreversible damage to the airways and lung tissue.",
"Symptoms include cough and shortness of breath, relating to underlying small airways disease with or without chronic bronchitis, and emphys... | [] |
Stress-induced plasticity and functioning of ventral tegmental dopamine neurons | The ventral tegmental area dopamine (VTA-DA) mesolimbic circuit processes emotional, motivational, and social reward associations together with their more demanding cognitive aspects that involve the mesocortical circuitry. Coping with stress increases VTA-DA excitability, but when the stressor becomes chronic the VTA-... | [
"NEUR",
"PSYC"
] | [
"Adaptation",
"Addiction",
"BDNF",
"CRH",
"Cognition",
"Coping",
"Depression",
"Dopamine",
"Glucocorticoids",
"Habituation",
"Mesocorticolimbic system",
"Microglia",
"Neurodegeneration",
"Opioids",
"Stress",
"Ventral tegmental area"
] | [
"2802",
"2805",
"3206"
] | [
"Although the stress response is essential for adaptation and survival, the term ‘stress’ is today generally associated with a negative experience (McEwen, 2013a,b).",
"Work-related stress is common and chronic exposure to stress is linked to various neuropsychiatric disorders, such as major depressive disorder (... | [
"mPFC coordinates VTA-linked emotional-motivational valuation with stress-coping.",
"CRH reduces, while opioids and glucocorticoids increase tonic VTA excitability.",
"VTA-DA neurons degenerate during chronic stress after a transient rise in excitability.",
"VTA-DA neurons are sexual dimorphic.",
"VTA-DA dy... |
The nature and origin of Charon's smooth plains | Charon displays extensive plains that cover the equatorial area and south to the terminator on the sub-Pluto hemisphere observed by New Horizons. We hypothesize that these plains are a result of Charon's global extension and early subsurface ocean yielding a large cryoflow that completely resurfaced this area leaving t... | [
"EART",
"PHYS"
] | [
"Charon",
"Cryovolcanism",
"Geological processes",
"Image processing",
"Pluto"
] | [
"1912",
"3103"
] | [
"New Horizons has provided the first geologically useful images of Pluto's moon Charon (Stern et al., 2015), which have revealed that its geology is strikingly diverse (Moore et al., 2016).",
"The Pluto-facing hemisphere, which was seen in the most detail by New Horizons during its flyby, is divided into two prim... | [
"The extensive plains on Charon are a result of global expansion and an early subsurface ocean that flowed as a cryoflow and resurfaced a large area.",
"The cryoflow most likely was composed of ammonia-rich water ice.",
"The cryoflow was similar to Lunar maria emplacement or via a mechanism where lithospheric b... |
The role of stabilization centers in protein thermal stability | The definition of stabilization centers was introduced almost two decades ago. They are centers of noncovalent long range interaction clusters, believed to have a role in maintaining the three-dimensional structure of proteins by preventing their decay due to their cooperative long range interactions. Here, this hypoth... | [
"BIOC"
] | [
"Protein stability",
"Stability changing mutations",
"Stabilization centers",
"Thermal stability",
"Thermophiles"
] | [
"1303",
"1304",
"1307",
"1312"
] | [
"We introduced the concept of stabilization centers (SCs) to solve the problem raised by the fact that the three-dimensional structure of a protein cannot be calculated from amino acid sequence considering only local (short range) interactions [1,2].",
"The idea of stabilization centers came from the fact that th... | [
"Stabilization centers contribute to thermal stabilization of protein structures.",
"Stabilization center content correlates with melting temperature of proteins.",
"Exposed stabilization center content correlates with stability even in hyperthermophiles.",
"Stability changing mutations are frequently found a... |
The day of the week effect in the cryptocurrency market | This paper examines the day of the week effect in the cryptocurrency market using a variety of statistical techniques (average analysis, Student's t-test, ANOVA, the Kruskal–Wallis test, and regression analysis with dummy variables) as well as a trading simulation approach. Most crypto currencies (LiteCoin, Ripple, Das... | [
"ECON"
] | [
"Anomaly",
"Bitcoin",
"Cryptocurrency",
"Day of the week effect",
"Efficient Market Hypothesis",
"Trading strategy"
] | [
"2003"
] | [
"There exists a vast literature analyzing calendar anomalies (the day of the week effect, the Turn of the Month Effect, the Month of the Year Effect, the January Effect, the Holiday Effect, the Halloween Effect etc.), and whether or not these can be seen as evidence against the Efficient Market Hypothesis (EMH – se... | [
"This paper examines the day of the week effect in the cryptocurrency market.",
"It using a variety of statistical techniques – as well as a trading simulation approach.",
"Most crypto currencies (LiteCoin, Ripple, Dash) are found not to exhibit this anomaly.",
"The only exception is BitCoin, for which return... |
CO2-dependent carbon isotope fractionation in dinoflagellates relates to their inorganic carbon fluxes | Carbon isotope fractionation (εp) between the inorganic carbon source and organic matter has been proposed to be a function of pCO2. To understand the CO2-dependency of εp and species-specific differences therein, inorganic carbon fluxes in the four dinoflagellate species Alexandrium fundyense, Scrippsiella trochoidea,... | [
"AGRI"
] | [
"CCM",
"CO2 uptake",
"HCO3- uptake",
"Leakage"
] | [
"1104",
"1105"
] | [
"During photosynthetic carbon fixation, the lighter carbon isotope 12C is preferred over the heavier carbon isotope 13C, thereby causing carbon isotope fractionation (εp) between the inorganic carbon (Ci) source and the organic carbon.",
"Values for εp of marine phytoplankton have been shown to be CO2-sensitive (... | [
"To understand 13C fractionation in dinoflagellates, inorganic carbon fluxes were measured by MIMS and used for modeling.",
"Changes in cellular carbon fluxes, i.e. HCO3− contribution and CO2 leakage were CO2-dependent.",
"These CO2-dependencies could largely explain the CO2-dependent fractionation patterns obs... |
Characterization and expression patterns of mannose-binding lectin (MMBL) gene in mulberry (Morus multicaulis) and its prokaryotic expression in E. coli | Mannose-binding lectin (MBL) is an important natural immune molecule which plays a significant role in plant self-defense and shows a broad spectrum resistance on plant pathogens, viral pathogens, and fungi. In the present paper, a cDNA sequence encoding MBL, which was designated MMBL (GenBank accession NO: KY348866), ... | [
"AGRI"
] | [
"Characterization",
"Expression analysis",
"Mannose-binding lectin",
"Mulberry",
"Prokaryotic expression"
] | [
"1110"
] | [
"Lectin is a kind of proteins possessing at least one noncatalytic domain, which binds reversibly to specific mono- or oligo- saccharides (Peumans and Van Damme 1995).",
"It has the role of agglutinating cells and precipitating glycan or sugar compounds (Agard and Bertozzi 2009).",
"Mannose-binding lectin (MBL)... | [
"MMBL gene was cloned from the leaves of mulberry (Morus multicaulis) that had an ORF of 486 bp encoding a protein of 161 amino acids.",
"The estimated molecular weight and pI of the putative protein were16.97 kDa and 6.07, respectively.",
"MMBL was expressed in all the tissues tested, including leaf, bud, frui... |
Room temperature phosphorescence lifetime and spectrum tuning of substituted thianthrenes | A group of thianthrene derivatives has been studied to investigate the effect of different substituents and substitution positions on their photophysical behavior. Strong room temperature phosphorescence (RTP) and dual fluorescence-phosphorescence at room temperature (RT-DFP) have been observed. Compounds with efficien... | [
"CENG"
] | [
"Phosphorescence",
"Photophysics",
"RT-DFP",
"RTP",
"Thianthrene"
] | [
"1500",
"1508"
] | [
"Thianthrene is a heterocyclic analog of anthracene but with two sulfur atoms substituting carbon atoms at the 9,10-positions.",
"This structure leads to a bent, non-aromatic geometry of the central thianthrene ring [1–3].",
"Thianthrenes are commonly known due to their interesting electrochemical properties [3... | [
"Thianthrene-based purely organic efficient room temperature phosphors are introduced.",
"Variable phosphorescence color, phosphorescence lifetime and fluorescence to phosphorescence ratio are observed.",
"Molecules are characterized using photophysical methods to explain the diversity of properties and substit... |
Peak car and increasing rebound: A closer look at car travel trends in Great Britain | This paper uses econometric analysis of aggregate time-series data to explore how different factors have influenced the demand for car travel in Great Britain since 1970 and how the rebound effect has changed over that time. Our results suggest that changes in income, the fuel cost of driving and the level of urbanisat... | [
"ENGI",
"ENVI",
"SOCI"
] | [
"Fuel efficiency",
"Peak car",
"Rebound effect"
] | [
"2205",
"2300",
"3313"
] | [
"Per capita car travel reached a plateau or began to decline in several OECD countries after the millennium, following more than half a century of continuous growth (Schipper, 2011; Van Dender and Clever, 2013).",
"In Great Britain (GB), per capita car travel reached a peak in 2002 and fell by 9% over the subsequ... | [
"We find that income, fuel costs and urbanisation are the main drivers of car travel trends in GB.",
"Urbanisation may be a proxy for several factors contributing to changes in car use.",
"We estimate the direct rebound effect for car travel in Great Britain to be around 26%",
"We estimate that the direct reb... |
Future land cover change scenarios in South African grasslands – implications of altered biophysical drivers on land management | Future land cover changes may result in adjustments to biophysical drivers impacting on net ecosystem carbon exchange (NEE), catchment water use through evapotranspiration (ET), and the surface energy balance through a change in albedo. The Land Change Modeller (Idrisi Terrset 18.08) and land cover for 2000 and 2014 ar... | [
"MULT"
] | [
"Environmental science",
"Geography"
] | [
"1000"
] | [
"Land use and land cover change (LULCC) has been suggested to be the most important anthropogenic disturbance to the environment at a local level, causing various microclimatic changes (Mishra and Rai, 2016).",
"Anthropogenic influences on the landscape such as alteration in land use through agriculture, forestry... | [] |
Nanoscale infrared identification and mapping of chemical functional groups on graphene | Chemical functionalisation of graphene and other 2-dimensional materials is a key step in realizing their full potential in various applications. There is a need for non-destructive and unambiguous identification of chemical groups and mapping of their distribution on such materials with nanoscale spatial resolution an... | [
"CHEM",
"MATE"
] | [] | [
"1600",
"2500"
] | [
"Graphene, and other 2-dimensional (2-d) materials, have shown tremendous potential for applications in the fields of sensors, printed electronics, composites and medicine to name but a few [1].",
"Most often, selective chemical functionalization of a 2-d material is necessary to increase compatibility or tailor ... | [] |
Quantifying the performance of MEG source reconstruction using resting state data | In magnetoencephalography (MEG) research there are a variety of inversion methods to transform sensor data into estimates of brain activity. Each new inversion scheme is generally justified against a specific simulated or task scenario. The choice of this scenario will however have a large impact on how well the scheme... | [
"NEUR"
] | [
"Empirical Bayesian beamformer",
"Forward model",
"Head-cast",
"Hidden Markov model",
"Inversion",
"LORETA",
"Magnetoencephalography",
"Minimum norm",
"Multiple sparse priors",
"Resolution",
"Resting state"
] | [
"2805",
"2808"
] | [
"Magnetoencephalography (MEG) detects electromagnetic fields at sensors outside the head.",
"The challenge for the researcher is to infer the neuronal current distribution responsible for the observed data, despite a much higher number of possible sources than sensors.",
"The general approach is to restrict the... | [
"Resting state data provides an unbiased dataset for comparing MEG source estimates.",
"We use a hidden Markov model to break the data into stationary segments.",
"We reconstruct these data onto a range of distorted cortical surfaces.",
"The sensitivity of any algorithm to spatial distortion is quantified in ... |
Real estate market and building energy performance: Data for a mass appraisal approach | Mass appraisal is widely considered an advanced frontier in the real estate valuation field. Performing mass appraisal entails the need to get access to base information conveyed by a large amount of transactions, such as prices and property features. Due to the lack of transparency of many Italian real estate market s... | [
"MULT"
] | [
"Building energy performance",
"Energy efficiency",
"Hedonic price",
"Mass appraisal",
"Real estate market"
] | [
"1000"
] | [
"The dataset features are as follows: 1,042 records, namely single unique properties, and 16 fields, namely property characteristics or other variables.",
"Table 1 provides an insight on the measurement scales of the variables, as well as their coding system.",
"The measurement scales have been defined accordin... | [] |
The dual function of social gaze | Ears cannot speak, lips cannot hear, but eyes can both signal and perceive. For human beings, this dual function makes the eyes a remarkable tool for social interaction. For psychologists trying to understand eye movements, however, their dual function causes a fundamental ambiguity. In order to contrast signaling and ... | [
"ARTS",
"NEUR",
"PSYC",
"SOCI"
] | [
"Eye movements",
"Eye tracking",
"Face perception",
"Social interaction",
"Social status"
] | [
"1203",
"2805",
"3204",
"3205",
"3310"
] | [
"You look across the card table, into the eyes of your opponent.",
"Are you searching their eyes for flickers of information, deciding whether to call their bluff?",
"Or by returning their stare are you letting them know that you have nothing to fear?",
"In social interactions, people use their eyes to percei... | [
"We manipulated beliefs about the social context of the viewing situation.",
"Change in beliefs alone produced different looking patterns to target faces.",
"We were able to dissociate signaling and perceiving functions of social gaze.",
"Face perception needs to address the dual function of social gaze."
] |
Regional free cash flow dataset: An approach to regional performance evaluation | This data article provides estimates on the Russian regions' aggregate free cash flow, which is not covered by national statistics of major countries. A proper microeconomic model was adapted to regional level data to derive a synthetic indicator of a regional economy's performance. The data contributes to the set of r... | [
"MULT"
] | [
"Economic development",
"Economic value",
"Free cash flow",
"Regional economy",
"Regional performance"
] | [
"1000"
] | [
"This article is associated to a Microsoft Excel Worksheet as a supplementary material.",
"The data contain time series of free cash flow values on the 85 Russian regions covering the period of 2006–2016.",
"No transformation was applied, except for scaling (all in thousands of Russian rubles).",
"Missing val... | [] |
Individual islet respirometry reveals functional diversity within the islet population of mice and human donors | Objective: Islets from the same pancreas show remarkable variability in glucose sensitivity. While mitochondrial respiration is essential for glucose-stimulated insulin secretion, little is known regarding heterogeneity in mitochondrial function at the individual islet level. This is due in part to a lack of high-throu... | [
"BIOC"
] | [
"Glucose",
"Islets",
"Mitochondria",
"Respirometry"
] | [
"1307",
"1312"
] | [
"Pancreatic islets rely on mitochondrial respiration to secrete insulin [1], a critical function for maintaining metabolic homeostasis.",
"A rise in extracellular glucose levels increases TCA cycle flux, mitochondrial respiration, and ATP synthesis in islet β-cells, which generates molecular signals stimulating a... | [
"Islets from the same pancreas show remarkable variability in glucose sensitivity.",
"Little is known about heterogeneity in mitochondrial respiration in individual islets.",
"We developed a novel high-throughput method to measure individual islet function.",
"Individual islets within a population show hetero... |
Intervening to change behaviour and save energy in the workplace: A systematic review of available evidence | Workplaces worldwide are a major source of carbon emissions and changing energy use behaviour in these environments has the capacity for large carbon savings. This paper reviews and synthesises empirical evidence to identify what types of behaviour change intervention are most successful at saving energy in an office-t... | [
"ENER",
"SOCI"
] | [
"Behaviour change",
"Behaviour change wheel",
"Energy use",
"Intervention",
"Review",
"Workplace"
] | [
"2102",
"2103",
"2104",
"2105",
"3301"
] | [
"Non-domestic buildings currently account for around 18% of UK carbon emissions [1] and 20% globally [2]; figures which are set to increase in the future, making workplaces an important focus for energy efficiency and energy saving initiatives around the world.",
"Various mechanisms exist to promote energy reduct... | [
"Studies of international workplace energy saving interventions are reviewed.",
"Enablement, Environmental Restructuring and Modelling most promising interventions.",
"Coercion, Restriction, and Training intervention types have been little researched.",
"Successful interventions create social and physical opp... |
Precise dating of the Middle-to-Upper Paleolithic transition in Murcia (Spain) supports late Neandertal persistence in Iberia | The late persistence in Southern Iberia of a Neandertal-associated Middle Paleolithic is supported by the archeological stratigraphy and the radiocarbon and luminescence dating of three newly excavated localities in the Mula basin of Murcia (Spain). At Cueva Antón, Mousterian layer I-k can be no more than 37,100 years-... | [
"MULT"
] | [
"Archaeology"
] | [
"1000"
] | [
"In the Aquitaine basin and the Pyrenees, the Middle Paleolithic (MP) Mousterian culture is followed, in succession, by the Châtelperronian, the Protoaurignacian and the Aurignacian I (a.k.a. Early Aurignacian).",
"In Iberia, these initial phases of the Upper Paleolithic (UP) are represented in the Cantabrian str... | [] |
Socio-cultural values as a dimension of fisheries governance: The cases of Baltic salmon and herring | The socio-cultural values associated with fish and fisheries affect the utilization and management of fish resources. However, these values often remain implicit in fisheries governance. This paper suggests addressing values explicitly to enhance the legitimacy of governance. We analyzed the values related to Baltic sa... | [
"ENVI",
"SOCI"
] | [
"Baltic herring",
"Baltic salmon",
"Fisheries governance",
"Socio-cultural values",
"Stakeholder involvement"
] | [
"2308",
"3305"
] | [
"The way in which fish resources are utilized and managed reflects the socio-cultural values associated with fish and fisheries.",
"Different species have different meanings in different contexts and groups (Lam, 2015; Levin et al., 2016).",
"Values also affect management decisions, either implicitly or explici... | [
"The multivalued nature of fish resources is demonstrated.",
"Values related to Baltic salmon and Baltic herring in two countries are compared.",
"Emphasis of values represented in fisheries governance depends on context.",
"Systematic inclusion of values in governance could enhance the legitimacy of decision... |
Effect of stirring rate on the morphology of FDU-12 mesoporous silica particles | Ordered mesoporous FDU-12 silica particles with different morphologies were synthesized by varying the stirring rate. The mesoporous structure and textural properties of the FDU-12 samples were characterized by N2 adsorption and desorption, scanning electron microscopy, transmission electron microscopy and small angle ... | [
"CHEM",
"ENGI",
"MATE",
"PHYS"
] | [
"FDU-12",
"Morphology",
"Ordered mesoporous silica",
"Stirring"
] | [
"1600",
"2211",
"2500",
"3104"
] | [
"Ordered mesoporous silica materials are applied in catalysis [1,2], molecular adsorption [3,4] and separation [5].",
"In addition to their internal textural properties (ordered and adjustable pore size, large surface area and pore volume), the external morphology of these materials also affects their applicabili... | [
"Morphology of FDU-12 mesoporous silica particles is controlled by changing the stirring rate during synthesis.",
"When increasing stirring rate, FDU-12 particle morphology changes from well-defined to poorly defined.",
"Internal pore structure and three-dimensional pore network topology are unchanged by stirri... |
Sleep homeostasis, habits and habituation | The importance of sleep for behavioural performance during waking is long-established, but the underlying reasons and mechanisms remain elusive. Waking and sleep are associated with changes in the levels of GluA1 AMPAR subunit in synaptic membranes, while studies using genetically-modified mice have identified an impor... | [
"NEUR"
] | [] | [
"2800"
] | [
"Over one hundred years of research has suggested that sleep and circadian rhythms play an important role in learning and memory.",
"Several hypotheses have been put forward to explain how sleep benefits learning, and why disrupted or mistimed sleep and sleep deprivation might affect cognitive function [1,2].",
... | [
"Synaptic GluA1 subunit levels increase during waking and decrease during sleep.",
"GluA1-dependent plasticity is implicated in short-term habituation.",
"Sleep may play a role in dishabituation, which restores attentional capacity.",
"Sleep disruption favours model-free/habit-based forms of behaviour."
] |
Influence of speech-language therapy on P300 outcome in patients with language disorders: a meta-analysis | Introduction: The patient's evolution in the audiology and speech-language clinic acts as a motivator of the therapeutic process, contributing to patient adherence to the treatment and allowing the therapist to review and/or maintain their clinical therapeutic conducts. Electrophysiological measures, such as the P300 e... | [
"MEDI"
] | [
"P300 evoked potential",
"Rehabilitation of speech and language disorders",
"Speech-Language therapy"
] | [
"2733"
] | [
"Patient evolution at the audiology and speech-language clinic acts as a motivator of the therapeutic process, contributing to patient adherence to treatment and allowing the therapists to review and/or maintain their clinical therapeutic conducts.1",
"Electrophysiological measures, in turn, help in the evaluatio... | [] |
Buyer and seller data from pay what you want and name your own price laboratory markets | Pay What You Want (PWYW) and Name Your Own Price (NYOP) are customer-driven pricing mechanisms that give customers (some) pricing power and that have been used in service industries with high fixed costs to price discriminate without setting a reference price. This paper describes buyer and seller data in a series of i... | [
"MULT"
] | [] | [
"1000"
] | [
"The data comprise buyer and seller behavior of a total of 384+144 subjects who participated in 8 different treatments of an experiment reported in Krämer et al., 2017: 6 treatments with exogenous benefits (NYOP monopoly, NYOP competition with fixed roles, NYOP competition with a flexible seller; PWYW monopoly, PWY... | [] |
Antioxidant properties and potential mechanisms of hydrolyzed proteins and peptides from cereals | Cereals like wheat, rice, corn, barley, rye, oat, and millet are staple foods in many regions around the world and contribute to more than half of human energy requirements. Scientific publications contain evidence showing that apart from energy, the regular consumption of whole grains is useful for the prevention of m... | [
"MULT"
] | [
"Food science",
"Nutrition"
] | [
"1000"
] | [
"Cereals are major sources of energy for populations around the world.",
"Taxonomic classification places them in the Gramineae or Poaceae family which is divided into seven major subfamilies of grasses, Bambusoideae, Oryzoideae, Pooideae, Panicoideae, Arundinoideae, Chloridoideae, and Centothecoideae, 40 tribes ... | [] |
Introducing MOZLEAP: An integrated long-run scenario model of the emerging energy sector of Mozambique | Since recently Mozambique is actively developing its large reserves of coal, natural gas and hydropower. Against this background, we present the first integrated long-run scenario model of the Mozambican energy sector. Our model, which we name MOZLEAP, is calibrated on the basis of recently developed local energy stati... | [
"ECON",
"ENER"
] | [
"Energy Modeling",
"Energy Sector",
"LEAP",
"Mozambique",
"Scenarios"
] | [
"2002",
"2100"
] | [
"Since recently Mozambique is actively developing its large reserves of coal, natural gas and hydropower.",
"Once developed, this could make Mozambique an important player in regional and global energy markets.",
"The recent IEA Africa Energy Outlook refers to Mozambique as an emerging large energy producer (to... | [
"Mozambique is now developing its large reserves of coal, natural gas and hydropower",
"We introduce the first comprehensive scenario model of its emerging energy sector",
"Until 2030, energy production increases at least six-fold, probably much more",
"Mozambique may well become a leading global producer of ... |
Mechanical allodynia induced by optogenetic sensory nerve excitation activates dopamine signaling and metabolism in medial nucleus accumbens | The mesolimbic dopaminergic signaling, such as that originating from the ventral tegmental area (VTA) neurons in the medial part of the nucleus accumbens (mNAc), plays a role in complex sensory and affective components of pain. To date, we have demonstrated that optogenetic sensory nerve stimulation rapidly alters the ... | [
"BIOC",
"NEUR"
] | [
"Dopamine",
"Imaging mass spectrometry",
"Mechanical allodynia",
"Nucleus accumbens",
"Optogenetics",
"Ventral tegmental area"
] | [
"1307",
"2804"
] | [
"The dopaminergic pathway, present from the ventral tegmental area (VTA) to the nucleus accumbens (NAc), is important for mediating acute and chronic pain sensations (Ikemoto, 2007; Taylor et al., 2016) and pain-avoidance behavior (Danjo et al., 2014).",
"The medial part of the NAc (mNAc) integrates signals from ... | [
"Regional DA metabolism in an optogenetic mouse model of mechanical allodynia was examined.",
"De novo synthesized DA occupied >10% of total DA pool in the striatum within 1.5 h.",
"Pain induced by tactile and optogenetic stimulation increased DA content in the mNAc.",
"Optogenetic stimulation without pain re... |
Hydrological variability affects particulate nitrogen and phosphorus in streams of the Northern Great Plains | Study region: The study area is located in southern Manitoba, in the prairie region of Canada Study focus: This study examined the impact of hydrological variability on the timing and magnitude of nutrient export from seven agriculturally-dominated watersheds in the Red River Valley, Manitoba, Canada. New hydrological ... | [
"EART",
"ENVI"
] | [
"Canadian prairies",
"Eutrophication",
"Hydroclimatology",
"Lake Winnipeg",
"Nutrients"
] | [
"1901",
"2312"
] | [
"Watersheds in the central Canadian prairies exhibit classic cold regions hydroclimatology, with long (4–5 month) cold winters followed by a short (2–5 week) spring characterized by warming temperatures, high surface runoff due to snowmelt over frozen soils, and peak discharge (Glozier et al., 2006; Fang et al., 20... | [
"Hydroclimatologic changes affected P and N concentrations and fractions.",
"Greater fractions of particulate P and N were observed during snowmelt in 2013.",
"Greater proportions of dissolved P were observed during snowmelt + rainfall in 2014.",
"Effective actions are needed to reduce dissolved P and N expor... |
Investigation into the applicability of Bond Work Index (BWI) and Hardgrove Grindability Index (HGI) tests for several biomasses compared to Colombian la Loma coal | With increasing quantities of biomass being combusted in coal fired power stations, there is an urgent need to be able to predict the grindability of biomass in existing coal mills, but currently no standard biomass grindability test exists. In this study, the applicability of the Hardgrove Grindability Index (HGI) and... | [
"CENG",
"CHEM",
"ENER"
] | [
"Biomass",
"Bond Work Index (BWI)",
"Coal",
"Energy consumption",
"Hardgrove Grindability Index (HGI)",
"Thermogravimetric analysis"
] | [
"1500",
"1605",
"2102",
"2103"
] | [
"Global coal consumption by power generators is growing annually [1].",
"With increasing legislation to reduce emissions from coal fired power stations in Europe [2,3], biomass combustion is playing an increasing role in the UK, Europe and beyond [4].",
"In order to minimise costs, biomass is often ground in ex... | [
"Bond Work Index (BWI) & Hardgrove Grindability Index (HGI) tests for biomass & coal.",
"BWI can predict the potential for mill choking of biomass in a tube and ball mill.",
"HGI is a poor method of predicting grindability of biomass in vertical spindle mills.",
"Pellets should be composed of pre-densified pa... |
Time-resolved biophysical approaches to nucleocytoplasmic transport | Molecules are continuously shuttling across the nuclear envelope barrier that separates the nucleus from the cytoplasm. Instead of being just a barrier to diffusion, the nuclear envelope is rather a complex filter that provides eukaryotes with an elaborate spatiotemporal regulation of fundamental molecular processes, s... | [
"BIOC",
"COMP"
] | [
"Confocal microscopy",
"Diffusion",
"Fluorescence correlation spectroscopy",
"Fluorescence recovery after photobleaching",
"GFP",
"Live cell",
"Nuclear pore complex",
"Single particle tracking",
"Transport"
] | [
"1303",
"1304",
"1305",
"1311",
"1315",
"1706"
] | [
"In eukaryotic cells, the cytoplasm and the nucleus are spatially separated by a double membrane, the nuclear envelope (NE).",
"Embedded in the NE are the nuclear pore complexes (NPCs), which allow the passage of ions and molecules across the NE and, at the same time, regulate the exchange of larger molecules, su... | [] |
Novel approaches in cancer management with circulating tumor cell clusters | Tumor metastasis is responsible for the vast majority of cancer-associated morbidities and mortalities. Recent studies have disclosed the higher metastatic potential of circulating tumor cell (CTC) clusters than single CTCs. Despite long-term study on metastasis, the characterizations of its most potent cellular driver... | [
"MATE"
] | [
"Cancer management",
"Circulating tumor cell cluster",
"Metastasis",
"Microfluidic CTC cluster",
"Passive detection techniques",
"Separation CTC cluster"
] | [
"2501",
"2502",
"2503",
"2504"
] | [
"Metastasis is a complicated, multistep process where cancer cells detach from the primary tumor, migrate to adjacent tissues, invade and travel through the bloodstream or the lymphatic system, survive, proliferate, colonize in distant organs and finally establish a new tumor (Fig. 1a) [1–12].",
"These tumor cell... | [] |
Primary and booster vaccination with an inactivated poliovirus vaccine (IPV) is immunogenic and well-tolerated in infants and toddlers in China | Introduction: Replacing live-attenuated oral poliovirus vaccines (OPV) with inactivated poliovirus vaccines (IPV) is part of the global strategy to eradicate poliomyelitis. China was declared polio-free in 2000 but continues to record cases of vaccine-associated-poliomyelitis and vaccine-derived-poliovirus outbreaks. T... | [
"BIOC",
"IMMU",
"MEDI",
"VETE"
] | [
"Booster",
"China",
"Eradication",
"Inactivated poliovirus vaccine",
"Oral poliovirus vaccine",
"Poliomyelitis",
"Poliovirus",
"Vaccine"
] | [
"1313",
"2400",
"2725",
"2739",
"3400"
] | [
"Oral poliovirus vaccine (OPV) has been the mainstay of poliomyelitis control in many countries since the 1950s.",
"Nonetheless, there are several disadvantages in continuing vaccination with OPV in countries where wild-type poliovirus has been eradicated.",
"Despite its otherwise remarkable safety profile, OPV... | [
"IPV safety and immunogenicity were assessed in the Chinese vaccination schedule.",
"IPV was non-inferior to Chinese OPV in terms of seroprotection rates.",
"IPV had a clinically acceptable safety profile in four studies.",
"IPV could feasibly be incorporated into Chinese vaccination schedule."
] |
Effect of copolymer composition on particle morphology and release behavior in vitro using progesterone | This study was aimed at improving dissolution rate and sustained release of progesterone by varying copolymer composition and polymer: drug ratio of PLGA. Drug-loaded particles were prepared using electrohydrodynamic atomization. The effects of polymer: drug ratio and copolymer composition on particle properties and in... | [
"ENGI",
"MATE"
] | [
"Drug delivery system",
"Electrohydrodynamic",
"Mathematical modelling",
"Progesterone"
] | [
"2210",
"2211",
"2500"
] | [
"In the development of oral formulations, the aqueous solubility of the drug plays a key role in the extent of drug absorption [1].",
"For any therapeutics to be successfully absorbed in the body, it needs to be present in the form of an aqueous solution at the desired site of action [1,2].",
"The solubility is... | [
"Single step electrospraying was applied with high processing yield to prepare drug delivery systems.",
"Solutions of PLGA with different monomer and drug ratios were used for producing progesterone-loaded microparticles.",
"Encapsulation efficiency of 80–90% was achieved in selected formulations.",
"The rele... |
Source apportionment of particle number size distribution in urban background and traffic stations in four European cities | Ultrafine particles (UFP) are suspected of having significant impacts on health. However, there have only been a limited number of studies on sources of UFP compared to larger particles. In this work, we identified and quantified the sources and processes contributing to particle number size distributions (PNSD) using ... | [
"ENVI"
] | [
"Airport emissions",
"Particle number size distributions",
"Photonucleation",
"Positive Matrix Factorization",
"Traffic emissions",
"Ultrafine particles"
] | [
"2300"
] | [
"It has been widely reported that atmospheric particulate matter (PM) has a negative impact upon human health, with 7 million deaths per year attributed to the exposure to air pollution (WHO, 2018).",
"Disentangling the impact on public health of the different sources contributing to PM would allow targeted polic... | [
"Ultrafine particle sources were identified and quantified in four European cities.",
"Common sources were Photonucleation, different Traffic sources, and Secondary.",
"Maximum contribution of traffic sources ranged 71–94% of total particle number.",
"Airport emissions contributed to nucleation particles in u... |
Intensification of convective heat transfer and heat exchanger performance by the combined influence of a twisted tube and twisted tape | Twisted tubes and twisted tapes are swirl flow generators utilized for increasing thermal performance. The combined effects of twisted tubes and twisted tapes on heat transfer, pressure drop and thermal performance were experimentally investigated. Experiments were performed using a trapezoidal shaped twisted tube and ... | [
"CENG",
"ENGI"
] | [
"Enhanced heat transfer",
"Heat exchanger tube",
"Swirl",
"Twisted tape",
"Twisted tube"
] | [
"1507",
"2201"
] | [
"Applying twisted tubes and twisted tapes has long been a method enhancing passive heat transfer in shell and tube heat exchangers.",
"Numerous applications are found in chemical processing plants, power plants and solar air/water heaters, and air conditioning equipment, among many others.",
"Twisted-tubes are ... | [] |
A physiological signature of sound meaning in dementia | The meaning of sensory objects is often behaviourally and biologically salient and decoding of semantic salience is potentially vulnerable in dementia. However, it remains unclear how sensory semantic processing is linked to physiological mechanisms for coding object salience and how that linkage is affected by neurode... | [
"NEUR",
"PSYC"
] | [
"Alzheimer's disease",
"Dementia",
"Frontotemporal",
"Nonverbal sound",
"Physiology",
"Progressive aphasia",
"Pupillometry",
"Semantic"
] | [
"2805",
"3205",
"3206"
] | [
"Disambiguation of potentially relevant, ‘salient’ stimuli from the busy multisensory background is accomplished efficiently and largely automatically by the healthy brain.",
"However, successful processing of sensory salience depends on a number of subprocesses: these include accurate parsing of the sensory envi... | [] |
Substrate recognition of holocytochrome c synthase: N-terminal region and CXXCH motif of mitochondrial cytochrome c | Holocytochrome c synthase (HCCS) attaches heme covalently to mitochondrial respiratory cytochromes c. Little is known about the reaction of heme attachment to apocytochromes c by HCCS, although recently it has been established that the CXXCH motif and the N-terminus of the apocytochrome polypeptide are important protei... | [
"BIOC"
] | [] | [
"1303",
"1304",
"1307",
"1311",
"1312",
"1315"
] | [
"The biosynthesis of cytochrome c is achieved by different systems in different organisms [1].",
"The heme group is covalently attached to apocytochrome in a critical and poorly understood step in this post-translational modification process.",
"A characteristic and highly conserved CXXCH motif occurs in the cy... | [
"Holocytochrome c synthase (HCCS) does not attach heme to cytochromes lacking the histidine in the CXXCH motif.",
"HCCS can recognise C-terminally truncated cytochromes c.",
"The aromatic nature of, or possibly shape complementarity to, F15 in cytochrome c is important for recognition by HCCS.",
"The spacing ... |
A robust and versatile mass spectrometry platform for comprehensive assessment of the thiol redox metabolome | Several diseases are associated with perturbations in redox signaling and aberrant hydrogen sulfide metabolism, and numerous analytical methods exist for the measurement of the sulfur-containing species affected. However, uncertainty remains about their concentrations and speciation in cells/biofluids, perhaps in part ... | [
"BIOC",
"CHEM"
] | [
"Glutathione",
"Hydrogen sulfide",
"Oxidative stress",
"Persulfides",
"Reactive species interactome",
"Redox status",
"Thiol-maleimide michael addition"
] | [
"1308",
"1605"
] | [
"Many biological processes that have previously been associated with an overproduction of reactive oxygen species (ROS) and/or an impaired antioxidant and free radical scavenging capacity were thought to culminate in ‘oxidative stress’, cell death and tissue damage.",
"More recently, such conditions are interpret... | [
"The thiol redox metabolome comprises free and bound thiols, disulfides, and sulfide.",
"We developed a LC-MS/MS platform for detection of the thiol redox metabolome in biological samples.",
"Thiols in blood, urine and saliva are stabilized by derivatization with N-ethylmaleimide, also preventing oxidation.",
... |
Effect of particle size on syngas production using sawdust of Cameroonian Triplochiton scleroxylon | Improving living comfort is inevitably accompanied by a significant increase in energy requirements. These constant rises in energy demand, coupled with environmental issues of fossil energies, have led researches toward renewable energies. Biomass is then one of the renewable sources of energy which must be valorized ... | [
"MULT"
] | [
"Gasification kinetic",
"Particle size",
"Pyrolysis",
"Syngas",
"Triplochiton scleroxylon"
] | [
"1000"
] | [
"Constant increase of population leads to a move up in energy requirements.",
"Because of the anxiety to global climate change, environmental pollution and limited resources of fossil energies, governments are constrained to migrate progressively from fossil energies to clean energies.",
"That explains why valo... | [] |
Using community-based system dynamics modeling to understand the complex systems that influence health in cities: The SALURBAL study | We discuss the design, implementation, and results of a collaborative process designed to elucidate the complex systems that drive food behaviors, transport, and health in Latin American cities and to build capacity for systems thinking and community-based system dynamics (CBSD) methods among diverse research team memb... | [
"SOCI"
] | [
"Community-based system dynamics",
"Diet",
"Group model building",
"Latin America",
"Transport"
] | [
"3306",
"3312",
"3319"
] | [
"Over half of the world's population, more than 4.1 billion people, lives in cities (World Bank, 2015).",
"In general, many health outcomes are better among urban populations than rural populations (Bai et al., 2012), although much heterogeneity exists both between and within cities.",
"Many factors associated ... | [
"CBSD methods can promote systems thinking and help identify policy approaches.",
"Stakeholders identified 98 variables driving food behaviors and transport in cities.",
"Balancing and reinforcing feedbacks drive change in food behavior and transport.",
"Feedback loops can also explain policy responses and la... |
Stress analysis of double-lap bi-material joints bonded with thick adhesive | Mechanics of double-lap Steel-to-CFRP adhesively-bonded joints loaded in tension are investigated experimentally using Digital Image Correlation (DIC) and Acoustic Emission (AE), analytically using a one-dimensional closed-form solution and numerically with Finite Element analysis. The double-lap bi-material joints are... | [
"CENG",
"MATE"
] | [
"AE",
"Acoustic emission",
"Composites",
"Mechanical properties of adhesives",
"Metals",
"Shear-lag model",
"Stress analysis"
] | [
"1500",
"2502",
"2507"
] | [
"The use of adhesively-bonded double-lap joints (DLJs) is preferred over conventional joining techniques such as bolting, riveting and welding.",
"They offer many advantages including, for instance, the ability to join dissimilar materials such as steel and fiber reinforced composites, weight savings, improved st... | [] |
Vegetation of Eurasia from the last glacial maximum to present: Key biogeographic patterns | Continental-scale estimates of vegetation cover, including land-surface properties and biogeographic trends, reflect the response of plant species to climate change over the past millennia. These estimates can help assess the effectiveness of simulations of climate change using forward and inverse modelling approaches.... | [
"AGRI",
"ARTS",
"EART",
"ENVI",
"SOCI"
] | [
"Biomes",
"Eurasia",
"Late Quaternary",
"Pollen",
"Vegetation"
] | [
"1105",
"1204",
"1907",
"2306",
"3302"
] | [
"Northern Eurasia (north of ca. 40°N and from 10°W to 180°E) is a large landmass with distinct gradients in climate.",
"The last deglaciation led to dramatic changes to the Earth system, and in the North polar amplification likely enhanced regional responses to climate forcing (Serreze and Barry, 2011).",
"The ... | [
"Pollen biomes for 1000-yr time slices from 21 to 0 ka BP are mapped for Eurasia.",
"Tundra and steppe biomes dominated 21–14 ka BP, but forest biomes were also present.",
"From 14 ka BP woody biomes expanded and wetland indicators became more prominent.",
"Extensive taxon list underlines importance of forbs ... |
Enhanced chondrogenesis from human embryonic stem cells | Human embryonic stem cells (hESCs) have great potential for the repair of damaged articular cartilage. We developed a serum-free 14-day protocol for hESC differentiation into chondrocyte progenitors, which surprisingly lacked strong cartilage matrix production in in vitro tests. In order to direct these progenitors to ... | [
"BIOC"
] | [] | [
"1307",
"1309"
] | [
"Hyaline cartilage forms the load-bearing surface of articular joints and is required for friction-free movement.",
"The tissue is avascular and aneural and is composed primarily of an extracellular matrix rich in type II collagen and proteoglycans.",
"It is maintained by a single cell type-the chondrocyte, whi... | [
"BMP2 stimulates increased chondrogenic gene expression from hESC chondroprogenitors compared to BMP4.",
"Other TGFΒ members were not effective.",
"BMP2 promoted COL2a1 positive aggregate formation.",
"with no effect on culture expansion or apoptosis."
] |
Cognitive and neural correlates of the 5-repeat allele of the dopamine D4 receptor gene in a population lacking the 7-repeat allele | The 5-repeat allele of a common length polymorphism in the gene that encodes the dopamine D4 receptor (. DRD4) is robustly associated with the risk of attention deficit hyperactivity disorder (ADHD) and substantially exists in Asian populations, which have a lower ADHD prevalence. In this study, we investigated the eff... | [
"NEUR"
] | [] | [
"2805",
"2808"
] | [
"The dopamine receptor D4 (DRD4) gene locates on chromosome 11p15.5.",
"As summarized previously (Swanson et al., 2000), this gene has a polymorphism in a coding region—a variable number of tandem repeats (VNTR) of a 48-base pair sequence in exon 3 (Lichter et al., 1993) that codes for a variation in the third in... | [
"Effects of 5-repeat (5R) allele of dopamine D4 receptor (DRD4) gene were examined.",
"5R carrier was associated with higher originality in the creativity task.",
"5R carrier was associated with lower mean diffusivity in the wide-spread areas.",
"5R carrier was associated with lower task-induced deactivation ... |
In vitro plant regeneration, phenolic compound production and pharmacological activities of Coleonema pulchellum | Effects of plant growth regulators (PGRs) and organic elicitors (OEs) on Coleonema pulchellum in vitro micropropagation, secondary product production and pharmacological activities were evaluated. In vitro, ex vitro and parental plants of C. pulchellum were investigated for their potential to produce phenolic and pharm... | [
"AGRI"
] | [
"Antibacterial activity",
"Antioxidants",
"In vitro regeneration",
"Organic elicitors",
"Phenolic compounds"
] | [
"1110"
] | [
"Coleonema pulchellum Williams (Rutaceae) is an evergreen, erect and dense shrub, which occurs from the western to the eastern Cape in South Africa.",
"It is an ideal aromatic garden plant which remains beautiful with pink flowers throughout the year.",
"The plant contains phenylpropenes, phenylpropanoids and t... | [
"In vitro propagation for Coleonema pulchellum is reported for the first time.",
"More normal and healthy shoots were obtained with 4.5 μM TDZ.",
"In vitro and ex vitro-grown C. pulchellum exhibited high bioactivities.",
"The protocol can be applied for mass propagation and plant transformation studies."
] |
Latitudinal gradient of spruce forest understory and tundra phenology in Alaska as observed from satellite and ground-based data | The latitudinal gradient of the start of the growing season (SOS) and the end of the growing season (EOS) were quantified in Alaska (61°N to 71°N) using satellite-based and ground-based datasets. The Alaskan evergreen needleleaf forests are sparse and the understory vegetation has a substantial impact on the satellite ... | [
"AGRI",
"EART"
] | [
"Alaska",
"Autumn phenology",
"Boreal forest",
"Radiative transfer analysis",
"Satellite SOS and EOS",
"Time-lapse camera",
"Tundra",
"Understory vegetation"
] | [
"1111",
"1903",
"1907"
] | [
"In the Arctic and sub-Arctic regions, including Alaska, warming trends have been accelerating and the increased trend in surface temperature in the region over the past decade is twofold higher than that in the whole northern hemisphere (Bekryaev, Polyakov, & Alexeev, 2010; Hinzman et al., 2013; IPCC, 2013).",
"... | [
"Forest understory and tundra phenology is estimated across Alaska from 61°N to 71°N.",
"Satellite estimates of spring onset were consistent with ground-based data.",
"From 84 to 86% of the NDVI seasonal amplitude can be used as a threshold for EOS.",
"The latitudinal gradients of SOS and EOS were 3.5 to 5.7 ... |
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