pmcid int32 60k 5.98M | pmid int32 11.7M 30M | text stringlengths 793 4.78k | label class label 2
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3,580,611 | 22,574,950 | BACKGROUND
Atherosclerotic intracranial arterial stenosis is an important cause of stroke that is increasingly being treated with percutaneous transluminal angioplasty and stenting (PTAS) to prevent recurrent stroke. However, PTAS has not been compared with medical management in a randomized trial.
METHODS
Objectiv... | 1significant effect |
5,101,645 | 27,847,704 | BACKGROUND
Caudal analgesia is a common method for postoperative pain management in pediatric patients. Additive agents such as opioids and α 2 agonists have been used to enhance the analgesic effects of local anesthetics for caudal block.
OBJECTIVES
The aim of this study was to compare the additive effects of dex... | 1significant effect |
4,639,339 | 26,622,078 | BACKGROUND AND OBJECTIVE
The use of sedative medications may be effective in the success and facilitation of the intussusception non-surgical treatment. Therefore, the purpose of this study was to examine the effect of midazolam on decreasing the duration of intussusception hydrostatic reduction in children.
MATERIAL... | 0no significant effect |
4,749,757 | 25,921,050 | BACKGROUND
Mobility impairment is a common disability in MS and negatively impacts patients' lives.
OBJECTIVE
Evaluate the effect of prolonged-release (PR) fampridine (extended-release dalfampridine in the United States) on self-assessed walking disability, dynamic/static balance and safety in patients with MS.
MET... | 1significant effect |
4,763,632 | 26,955,122 | BACKGROUND
Phototherapy may alter the morphologic features of melanocytic nevi. Dermoscopy is a non-invasive method for evaluation of skin lesions, specifically melanocytic nevi.
AIMS AND OBJECTIVES
This study was designed to evaluate the effects of narrowband ultraviolet B (NB-UVB) and psoralen-ultraviolet A (PUVA... | 1significant effect |
2,662,857 | 19,284,641 | BACKGROUND
Several uncontrolled studies of hyperbaric treatment in children with autism have reported clinical improvements; however, this treatment has not been evaluated to date with a controlled study. We performed a multicenter, randomized, double-blind, controlled trial to assess the efficacy of hyperbaric treat... | 1significant effect |
3,210,361 | 21,603,893 | RATIONALE
Disturbances in the subjective experience of time have been observed both in schizophrenia and following acute administration of ketamine. However, effects of ketamine on more objective timing tasks have not yet been measured in humans, nor has it been established that timing effects are not merely secondar... | 1significant effect |
2,806,387 | 20,076,777 | BACKGROUND
Nurses at The Norwegian Radium Hospital have reported that some patients notice an unpleasant smell or taste in accordance with flushing of intravenous lines with commercially available prefilled syringes. We have conducted a study in healthy volunteers to investigate the occurrence, consistency and intens... | 1significant effect |
4,574,984 | 26,378,939 | PURPOSE
This randomized controlled, clinical prospective interventional trial was aimed at exploring the effect of patient empowerment on short- and long-term outcomes after major oncologic surgery in elderly cancer patients.
METHODS
This trial was performed from February 2011 to January 2014 at two tertiary medica... | 1significant effect |
5,808,396 | 29,449,879 | BACKGROUND
Sexual violence is associated with a multitude of poor physical, emotional, and social outcomes. Despite reports of stigma by sexual violence survivors, limited evidence exists on effective strategies to reduce stigma, particularly in conflict-affected settings. We sought to assess the effect of group Cogn... | 1significant effect |
5,038,569 | 27,703,326 | AIM
To report the efficacy of intravitreal ziv-aflibercept injections in eyes with macular edema due to retinal vein occlusions (RVOs).
METHODS
Consecutive patients with persistent or recurrent macular edema (central macula thickness >250 μm) due to RVO were enrolled in this prospective study. Study eyes received i... | 1significant effect |
3,376,507 | 22,555,246 | BACKGROUND
The development and use of Web-based programs for weight loss is increasing rapidly, yet they have rarely been evaluated using randomized controlled trials (RCTs). Interestingly, most people who attempt weight loss use commercially available programs, yet it is very uncommon for commercial programs to be e... | 1significant effect |
4,714,728 | 26,811,685 | BACKGROUND
The aim of this study was to evaluate the therapeutic effect of autogenous semitendinosus graft and endobutton technique, and compare with hook plate in treatment of Rockwood type III acromioclavicular (AC) joint dislocation.
METHODS
From April 2012 to April 2013, we treated 46 patients with Rockwood typ... | 1significant effect |
5,808,689 | 29,445,266 | OBJECTIVES
Our aim was to study whether the acute care of frail elderly patients directly admitted to a comprehensive geriatric assessment (CGA) unit is superior to the care in a conventional acute medical care unit in terms of patient satisfaction.
DESIGN
TREEE (Is the TReatment of frail Elderly patients Effective... | 0no significant effect |
4,199,615 | 25,329,405 | OBJECTIVE
We examined metabolic and endocrine responses during rest and exercise in moderate hypoxia over a 7.5 h time courses during daytime.
METHODS
Eight sedentary, overweight men (28.6 ± 0.8 kg/m2) completed four experimental trials: a rest trial in normoxia (FiO2 = 20.9%, NOR-Rest), an exercise trial in normox... | 0no significant effect |
3,956,949 | 24,648,875 | PURPOSE
To compare the safety and efficacy of tamsulosin and tamsulosin with the phosphodiesterase-5 inhibitor tadalafil in combination with prednisolone as medical expulsive therapies for lower ureteric stones.
MATERIALS AND METHODS
Between July 2011 and December 2012, 62 adult patients presenting with distal uret... | 1significant effect |
4,296,406 | 25,624,646 | BACKGROUND
Stress-related mucosal disease occurs in many critically ill-patients within 24 h of admission. Proton pump inhibitor therapy has been documented to produce more potent inhibition of gastric acid secretion than histamine 2 receptor antagonists. This study aimed to compare extemporaneous preparations of ome... | 1significant effect |
4,760,038 | 26,955,308 | BACKGROUND
Ultrasound-guided paravertebral blocks during breast surgeries with in-plane needle approaches can be challenging due to difficult needle visualization. The purpose of this study was to assess the usefulness of using a needle guide while performing in-plane parasagittal approach paravertebral block for bre... | 1significant effect |
4,266,420 | 25,525,398 | PURPOSE
To investigate the potential benefit of post-race wearing of unstable shoes (Masai Barefoot Technology [MBT]) on recovery from marathon race-induced fatigue.
PATIENTS AND METHODS
Forty-five runners who participated in a full marathon race were divided into three groups: 1) MBT shoes, 2) trail running shoes,... | 1significant effect |
5,054,611 | 27,716,165 | BACKGROUND
The Laryngeal Tube Suction Disposable (LTS-D) and the Supreme Laryngeal Mask Airway (SLMA) are second generation supraglottic airway devices (SADs) with an added channel to allow gastric drainage. We studied the efficacy of these devices when using pressure controlled mechanical ventilation during general ... | 1significant effect |
3,549,413 | 22,302,614 | PURPOSE
Many postmenopausal women desire non-pharmaceutical alternatives to hormone therapy for protection against osteoporosis. Soybean isoflavones, especially genistein, are being studied for this purpose. This study examined the effects of synthetic genistein in combination with other potential bone-protective die... | 1significant effect |
4,802,087 | 25,946,929 | AIM
This study aimed to evaluate the effects of vitamin D intake on COPD exacerbation and FEV1 in the patients with severe and very severe COPD.
METHODS
This double blind placebo control randomized clinical trial study was done in the Ashayer university hospital in Khorramabad in 2012. Eighty eight patients with se... | 1significant effect |
4,341,495 | 25,763,266 | BACKGROUND
Substance abuse or drug addiction is one of the most important health issues in every society, which can lead to physical and mental problems.
OBJECTIVES
This study aimed to compare the efficacy of tramadol plus gabapentin versus methadone use in the treatment of opiate withdrawal.
PATIENTS AND METHODS
... | 0no significant effect |
4,131,263 | 25,065,692 | BACKGROUND
Meta-analyses suggest that reboxetine may be less effective than other antidepressants. Such comparisons may be biased by lower adherence to reboxetine and subsequent handling of missing outcome data. This study illustrates how to adjust for differential non-adherence and hence derive an unbiased estimate ... | 0no significant effect |
3,445,058 | 23,015,971 | BACKGROUND
Active-assistive range of motion exercises to gain shoulder elevation have been subdivided into gravity-minimized and upright-assisted exercises, yet no study has evaluated differences in muscular demands.
HYPOTHESIS
Compared with gravity-minimized exercises, upright-assisted exercises will generate larg... | 1significant effect |
3,878,739 | 24,330,619 | BACKGROUND
Our main objective was to evaluate the ability of cranberry phytochemicals to modify immunity, specifically γδ-T cell proliferation, after daily consumption of a cranberry beverage, and its effect on health outcomes related to cold and influenza symptoms.
METHODS
The study was a randomized, double-blind,... | 1significant effect |
4,874,073 | 27,275,048 | BACKGROUND AND AIM
Induced hypotension limits intra-operative blood loss to provide better visibility of the surgical field and diminishes the incidence of major complications during functional endoscopic sinus surgery (FESS). We aimed at comparing nitroglycerine, esmolol and dexmedetomidine for inducing controlled h... | 1significant effect |
2,801,838 | 19,672,550 | BACKGROUND
Lutein is a carotenoid that may play a role in eye health. Human milk typically contains higher concentrations of lutein than infant formula. Preliminary data suggest there are differences in serum lutein concentrations between breastfed and formula-fed infants.
AIM OF THE STUDY
To measure the serum lute... | 1significant effect |
2,806,530 | 20,020,107 | INTRODUCTION
Alcohol has renowned behavioral disinhibitory properties which are suggested to involve reductions in frontal lobe functioning as a result of diminished interhemispheric connectivity.
METHODS
To examine sex differences in frontal interhemispheric connectivity in response to alcohol, 12 female and ten m... | 1significant effect |
5,385,703 | 28,516,068 | BACKGROUND
Vitiligo, a common disorder of depigmentation, is often difficult to treat. Corticosteroids are known to be effective, but with modest results. Although simvastatin has been reported to be effective for immunorelated dermatologic disorders including vitiligo, controlled trials are lacking. This study was c... | 0no significant effect |
3,019,750 | 21,228,955 | OBJECTIVES
This in situ study evaluated the effect of saliva, associated or not with fluoride, on enamel previously submitted to prophylaxis using sodium bicarbonate.
METHODS
The study was conducted on enamel blocks submitted to in vitro prophylaxis using sodium bicarbonate. The blocks were randomly divided into 2 ... | 0no significant effect |
3,599,990 | 23,510,189 | BACKGROUND
Self-reported weight and height is frequently used to quantify overweight and obesity. It is however, associated with limitations such as bias and poor agreement, which may be a result of social desirability or difficulties with recall. Methods to reduce these biases would improve the accuracy of assessmen... | 0no significant effect |
3,604,854 | 23,543,763 | BACKGROUND
This study aimed to compare two doses of Mitomycin C in reducing haze formation after photorefractive keratectomy.
METHODS
170 eyes of 85 patients enrolled; in each patient one eye randomly assigned to be treated by low dose intraoperative MMC (LDMMC) and other eye by standard dose MMC (SDMMC). Then the ... | 0no significant effect |
4,053,826 | 24,281,275 | OBJECTIVES
Local anesthetic wound infiltration is widely used as an effective adjunct during multimodal postoperative pain management. The aim of this study was to evaluate the effectiveness of continuous wound infusion of ropivacaine in postoperative pain relief, opioid sparing, incidence of nausea and vomiting, and... | 1significant effect |
3,688,436 | 23,807,849 | INTRODUCTION
A significant number of mania patients fail to respond to current pharmacotherapy, thereby there is need for novel augmentation strategies. The results of some early studies showed the effectiveness of cholinomimetics in the treatment of mania. One open case series suggested the efficacy of donepezil in ... | 0no significant effect |
5,079,604 | 27,573,938 | OBJECTIVE
After intensive insulin treatment, many obese African American patients with new-onset diabetic ketoacidosis (DKA) and severe hyperglycemia are able to achieve near-normoglycemia remission. The optimal treatment to prevent hyperglycemic relapses after remission is not known.
RESEARCH DESIGN AND METHODS
Th... | 1significant effect |
3,329,100 | 22,529,513 | OBJECTIVE
Elevated white blood cell (WBC) count is considered to be prospectively and positively associated with cardiovascular diseases, particularly hypertension. Also, the positive role of exercise in the management of hypertension has been well and long established. However the relationship between WBC count and ... | 1significant effect |
5,870,330 | 29,599,691 | OBJECTIVES
The main goal of this study was to evaluate the fracture resistance of maxillary second premolar teeth with standard and conservative mesio-occluso-distal (MOD) cavity designs.
METHODS
Sixty maxillary second premolars were randomly divided into 6 Groups of 10 teeth. G1 consisted of intact teeth. G2 was p... | 1significant effect |
4,112,748 | 25,092,964 | BACKGROUND
Migraine is a painful neurological disorder that affects over 10% of the general population. Frovatriptan and rizatriptan are antimigraine agents belonging to the triptan class. Although previous studies have independently compared the efficacy of these agents, contemporaneous data examining both pharmacok... | 0no significant effect |
5,106,877 | 28,042,548 | BACKGROUND
Vitamin D (Vit D) deficiency is a common disorder in diabetic patients and may be a risk factor for ischemic heart disease and exacerbation of diabetic nephropathy(DN).
OBJECTIVES
The aim of this study was to evaluate the effect of Vit D3 therapy on protein uriain type 2 diabetic patients with deficient ... | 1significant effect |
5,129,820 | 27,824,811 | BACKGROUND
Maintenance monotherapy with the poly(ADP-ribose) polymerase inhibitor olaparib significantly prolongs progression-free survival over placebo in patients with platinum-sensitive relapsed serous ovarian cancer, with greatest benefit seen in patients with a BRCA1/2 mutation (BRCAm). Preservation of health-re... | 0no significant effect |
3,267,052 | 22,093,005 | AIM
A double-blind randomized controlled trial to determine whether dietary supplementation with fruit/vegetable/berry juice powder concentrates, simultaneously with non-surgical periodontal therapy, improved 2-month treatment outcomes.
METHODS
Volunteers with chronic periodontitis were randomly assigned to one of ... | 1significant effect |
4,884,260 | 27,275,337 | AIM
The aim of this study is to evaluate anesthesia and recovery profile in pediatric patients after inguinal hernia repair with caudal block or local wound infiltration.
MATERIAL AND METHODS
In this prospective interventional clinical study, the anesthesia and recovery profile was assessed in sixty pediatric patie... | 0no significant effect |
3,893,543 | 24,410,973 | BACKGROUND
Increasing numbers of reports show the beneficial effects of listening to Mozart music in decreasing epileptiform discharges as well as seizure frequency in epileptic children. There has been no effective method to reduce seizure recurrence after the first unprovoked seizure until now. In this study, we in... | 1significant effect |
4,776,564 | 26,985,226 | BACKGROUND
Heart failure is one of the most important and prevalent diseases that may have negative effects on the quality of life (QOL). Today, the promotion of QOL in patients with heart failure is important in nursing care programs. This research aimed to determine the efficacy of hope-promoting interventions base... | 1significant effect |
4,972,969 | 27,488,692 | BACKGROUND
Integrated Infectious Diseases Capacity Building Evaluation (IDCAP) teams designed and implemented two health worker in-service training approaches: 1) an off-site classroom-based integrated management of infectious diseases (IMID) course with distance learning aspects, and 2) on-site support (OSS), an edu... | 1significant effect |
2,430,617 | 18,596,958 | BACKGROUND
The safety of the immune complexes composed of yeast-derived hepatitis B surface antigen (HBsAg) and antibodies (abbreviated as YIC) among healthy adults and chronic hepatitis B patients has been proved in phase I and phase IIa trial. A larger number of patients for study of dosage and efficacy are therefo... | 1significant effect |
5,781,260 | 29,410,606 | BACKGROUND
Exhaustive exercise causes muscle damage accompanied by oxidative stress and inflammation leading to muscle fatigue and muscle soreness. Lemon verbena leaves, commonly used as tea and refreshing beverage, demonstrated antioxidant and anti-inflammatory properties. The aim of this study was to investigate th... | 0no significant effect |
5,126,155 | 27,823,996 | BACKGROUND
High cost of imported pacemakers is a main obstacle for Chinese patients suffering from bradyarrhythmia, and a domestically developed pacemaker will help lower the burden. This study aimed to evaluate the safety and efficacy of Qinming8631 DR (Qinming Medical, Baoji, China), the first domestically develope... | 0no significant effect |
4,069,273 | 24,934,646 | BACKGROUND
Currently, there is an increased prevalence of diabetes mellitus among the elderly. To minimize adverse effects on glycemic control, prevention and management of general and oral complications in diabetic patients is essential. The purpose of the present study is to assess the effectiveness of a Lifestyle ... | 1significant effect |
4,021,263 | 24,851,129 | BACKGROUND
Mycobacterial identification in active pulmonary tuberculosis (APTB) is confirmative, even though successful rates using self-expectorated sputum are limited. Sputum specimens collected by hypertonic saline nebulization showed higher bacteriologic diagnostic sensitivities over those of self-expectoration, ... | 1significant effect |
4,387,644 | 25,878,697 | BACKGROUND
Hypertension in pregnancy is one of the prevalent disorder resulting in maternal death. The aim of this study was to investigate the effect of stretching exercise and walking on changes of blood pressure in nulliparous women during pregnancy.
MATERIALS AND METHODS
This was a quasi-experimental trial that... | 0no significant effect |
4,155,124 | 25,128,296 | BACKGROUND
Increased circulating cathepsin S levels have been linked to increased risk of cardiometabolic diseases and cancer. However, whether cathepsin S is a modifiable risk factor is unclear. We aimed to investigate the effects of a prudent diet on plasma cathepsin S levels in healthy individuals.
FINDINGS
Expl... | 1significant effect |
5,148,913 | 27,938,358 | BACKGROUND
A high strength of beclomethasone/formoterol fumarate (BDP/FF) in a pressurised metered dose inhaler (pMDI), which contains extrafine BDP (200 μg/actuation) and FF (6 μg/actuation) has been developed to treat those asthmatics who are not adequately controlled on previous treatments.
METHODS
A 12-week, ra... | 1significant effect |
4,152,682 | 25,190,950 | BACKGROUND AND AIMS
Transversus abdominis plane (TAP) block has been shown to provide postoperative pain relief following various abdominal and inguinal surgeries, but few studies have evaluated its analgesic efficacy for intraoperative analgesia. We evaluated the efficacy of TAP block in providing effective perioper... | 1significant effect |
5,452,353 | 28,572,749 | BACKGROUND
Recent research has indicated that pomegranate extract (POMx) may improve performance during aerobic exercise by enhancing the matching of vascular oxygen (O 2 ) provision to muscular requirements. POMx is rich in ellagitannin polyphenols and nitrates (NO 3 - ), which are both associated with improvements ... | 1significant effect |
4,323,894 | 25,685,201 | BACKGROUND
Induced hypothermia for treatment of traumatic brain injury is controversial. Since many pathways involved in the pathophysiology of secondary brain injury are temperature dependent, regional brain hypothermia is thought capable to mitigate those processes. The objectives of this study are to assess the th... | 0no significant effect |
4,630,743 | 26,604,599 | BACKGROUND
Misoprostol is very effective in cervical ripening and is used for termination of pregnancy. A similar effect on the nonpregnant uterus will facilitate gynecological operations, and hence we assessed the effect of misoprostol on the nonpregnant uterus of premenopausal women.
MATERIALS AND METHODS
In a pr... | 1significant effect |
5,864,139 | 27,630,212 | OBJECTIVE
We evaluated the incidence of acute pancreatitis and pancreatic cancer in patients with type 2 diabetes and cardiovascular disease who were treated with sitagliptin, a dipeptidyl peptidase-4 inhibitor (DPP-4i).
RESEARCH DESIGN AND METHODS
In the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (T... | 0no significant effect |
5,735,476 | 29,284,837 | INTRODUCTION
Spinal anesthesia is preferred technique of choice in infraumbalical surgeries. Limitation of this technique is shorter duration of analgesia, so various adjuvants have been used with intrathecal bupivacaine such as fentanyl, clonidine, and dexmedetomidine. Dexmedetomidine is a highly selective alpha 2 a... | 1significant effect |
5,601,935 | 29,177,245 | BACKGROUND
Different combination of gonadotropin preparation has been introduced with no definite superiority of one over others in in vitro fertilization (IVF), but individualized regimens for each patient are needed.
OBJECTIVE
The aim of the present study was to investigate the effect of controlled ovarian stimul... | 0no significant effect |
2,762,969 | 19,811,624 | BACKGROUND
Type 2 diabetes mellitus is a complex, progressive disease which requires a variety of quality improvement strategies. Limited information is available on the feasibility and effectiveness of interdisciplinary diabetes care teams (IDCT) operating on the interface between primary and specialty care. A first... | 1significant effect |
2,928,344 | 20,805,274 | OBJECTIVE
We investigated whether supplementation of the active form of vitamin D (calcitriol) in recent-onset type 1 diabetes can protect beta-cell function evaluated by C-peptide and improve glycemic control assessed by A1C and insulin requirement.
RESEARCH DESIGN AND METHODS
Thirty-four subjects (aged 11-35 year... | 0no significant effect |
3,214,395 | 22,091,306 | BACKGROUND
Induction of anesthesia is the most crucial period of general anesthesia. Inhalational induction is the most commonly used technique in pediatric anesthesia. Tracheal intubation can be done after reaching the deep levels of anesthesia. The depth of anesthesia is often difficult to be judged. Bispectral ind... | 0no significant effect |
4,726,501 | 26,808,136 | BACKGROUND
Low-dose aspirin is widely recommended for patients at high risk for cardiovascular disease (CVD); however, it remains uncertain whether long-term treatment adversely affects renal function in patients with diabetes. We investigated whether long-term low-dose aspirin affects renal dysfunction in patients w... | 0no significant effect |
4,787,139 | 27,013,746 | BACKGROUND AND AIMS
Midazolam-fentanyl (MDZ:FEN) combination has been routinely used for intravenous sedation in ophthalmic surgeries. Dexmedetomidine (DEX), a recent α2 adrenoreceptor agonist indicated for sedation for ophthalmic use at a loading dose of 0.5 μg/kg over 10 min, can cause deeper plane of sedation and ... | 1significant effect |
3,994,428 | 24,650,002 | BACKGROUND
Intracranial-pressure (ICP) monitoring is considered standard care for severe traumatic brain injury and is used frequently, but the efficacy of treatment based on monitoring in patients with hemorrhagic stroke has not been rigorously assessed. In this study, we investigated the clinical value of ICP monit... | 1significant effect |
4,188,585 | 25,290,151 | BACKGROUND
Persistent pain after inguinal herniorrhaphy is a disabling condition with a lack of evidence-based pharmacological treatment options. This randomized placebo-controlled trial investigated the efficacy of a capsaicin 8% cutaneous patch in the treatment of severe persistent inguinal postherniorrhaphy pain.
... | 0no significant effect |
5,156,970 | 28,028,528 | BACKGROUND
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder. Recent studies suggest the importance of gut flora in the pathophysiology of it. Therefore, antibiotics have demonstrated a substantial benefit to reduce gut flora. Having few side effects, and applying one-dose per day, we studied the e... | 1significant effect |
4,083,640 | 24,831,401 | OBJECTIVE
To evaluate whether the acute pain experienced during in-hospital recovery from thoracotomy can be effectively reduced by the use of intraoperative measures (dissection of the neurovascular bundle prior to the positioning of the Finochietto retractor and preservation of the intercostal nerve during closure)... | 1significant effect |
5,094,682 | 27,812,149 | OBJECTIVE
To assess the effect of pioglitazone on renal outcome, including urinary albumin excretion and estimated glomerular filtration rate (eGFR), in diabetic patients.
DESIGN
A prospective, randomized, open-labeled, controlled study.
SETTING
Taipei Veterans General Hospital.
PATIENTS
Sixty type 2 diabetic p... | 0no significant effect |
5,842,771 | 29,551,889 | BACKGROUND
Alzheimer's disease (AD) is a slowly progressive neurodegenerative disease which cannot be cured at present. The aim of this study was to assess whether the combined application of β-asarone and tenuigenin could improve the efficacy of memantine in treating moderate-to-severe AD.
PATIENTS AND METHODS
One... | 1significant effect |
3,503,942 | 23,185,731 | OBJECTIVE
To investigate the effect of extracorporeal shock wave therapy (ESWT) on myofascial pain syndrome (MPS).
METHOD
Thirty patients with MPS in trapezius muscle were randomly divided into two groups, ESWT group (n=15), and trigger point injections (TPI)+transcutaneous electrical nerve stimulation (TENS) group... | 1significant effect |
3,652,505 | 23,682,330 | BACKGROUND
Considerable reports concerned the framing effect in medical situations. But quite few of them noticed to explore the differences among the various kinds of framing effects.
OBJECTIVES
In the present study, five different types of framing effects were examined and the effect sizes of them were compared.
... | 1significant effect |
3,994,324 | 24,655,814 | BACKGROUND
Improving adherence to ocular hypertension (OH)/glaucoma therapy is highly likely to prevent or reduce progression of optic nerve damage. The present study used a behaviour change counselling intervention to determine whether education and support was beneficial and cost-effective in improving adherence wi... | 0no significant effect |
3,958,613 | 24,653,737 | BACKGROUND AND OBJECTIVES
Increased bleeding rates with standard dose prasugrel have led to increased questions about the effectiveness and safety of the lower maintenance dose. We compared platelet inhibitory efficacy between low dose prasugrel and standard dose clopidogrel in patients on maintenance dose dual antip... | 1significant effect |
4,464,926 | 25,662,551 | BACKGROUND
To evaluate the intensity of pain, swelling and trismus after the removal of impacted lower third molars comparing two different suture techniques of the triangular flap: the complete suture of the distal incision and relieving incision and the partial suture with only one suture knot for closure of the co... | 0no significant effect |
3,712,888 | 23,864,922 | BACKGROUND
The aetiology of bacterial vaginosis (BV) is still unclear but it is currently considered to be a synergistic polymicrobial syndrome. BV can often arise as a chronic or recurrent disease. The reason for such recurrences is not well elucidated. Previous studies have suggested that vaginal vitamin C may be a... | 1significant effect |
5,682,159 | 29,184,723 | BACKGROUND
Patient-reported outcomes are important measures when assessing the efficacy of aesthetic procedures.
OBJECTIVE
To compare outcomes between 2 volumizing hyaluronic acid fillers.
MATERIALS AND METHODS
Subjects with moderate-to-severe volume loss in the cheeks were randomized in a split-face design to ma... | 0no significant effect |
4,610,927 | 26,495,058 | BACKGROUND
Opioid induced hyperalgesia (OIH) is related with high opioid dosage, a long duration of opioid administration, and abrupt discontinuation of infused opioids in anesthetic settings. Ketamine is known to attenuate OIH efficiently, but methods of administration and methods to quantify and assess a decrease i... | 0no significant effect |
3,662,597 | 23,680,036 | BACKGROUND
The cardiovascular (CV) and metabolic health benefits or risks associated with consumption of multi-ingredient performance supplements (MIPS) in conjunction with periodized resistance training (RT) in resistance-trained men are unknown. This population is a major target audience for performance supplements... | 0no significant effect |
5,219,826 | 27,161,603 | PURPOSE
To compare the visual performance of prototype contact lenses which extend depth-of-focus (EDOF) by deliberate manipulation of multiple higher-order spherical aberration terms and a commercially-available center-near lens (AIR OPTIX Aqua Multifocal, AOMF).
METHODS
This was a prospective, cross-over, randomi... | 1significant effect |
5,633,216 | 29,038,700 | BACKGROUND
Chlorhexidine (CHX) is the most effective antiseptic mouthwash to date. Essential oil such as thymol, have inhibitory and biocidal effects a range of bacteria.
OBJECTIVE
To determine the effect of mouthwash containing CHX and thymol on plaque induced gingivitis.
METHODS
This double-blind randomized cli... | 1significant effect |
4,568,196 | 26,405,440 | BACKGROUND
The effect of legume-based hypocaloric diet on cardiovascular disease (CVD) risk factors in women is unclear. This study provides an opportunity to find effects of high-legume diet on CVD risk factors in women who consumed high legumes at baseline.
METHODS
This randomized controlled trial was undertaken ... | 1significant effect |
3,475,525 | 22,995,103 | INTRODUCTION
Governments throughout the world are using or considering various front-of-package (FOP) food labeling systems to provide nutrition information to consumers. Our web-based study tested consumer understanding of different FOP labeling systems.
METHODS
Adult participants (N = 480) were randomized to 1 of... | 1significant effect |
4,594,140 | 26,448,852 | BACKGROUND
It has been reported that high intensity long term training in elite athletes may increase risk of immune function.
OBJECTIVES
This study is to examine training effects on immunoglobulin and changes of physiological stress and physical fitness level induced by increased cold stress during 12-week winter ... | 1significant effect |
3,321,403 | 22,500,253 | PURPOSE
Painful bladder syndrome/interstitial cystitis (PBS/IC) is a disabling disease of the urinary bladder, and its etiology and treatment are not yet established. Current medications used in the treatment of PBS/IC have shown limited efficacy. This prospective study investigated the efficacy of intravesical resin... | 0no significant effect |
4,297,469 | 25,179,766 | AIM
Remote follow-up (FU) of implantable cardiac defibrillators (ICDs) allows for fewer in-office visits in combination with earlier detection of relevant findings. Its implementation requires investment and reorganization of care. Providers (physicians or hospitals) are unsure about the financial impact. The primary... | 1significant effect |
2,788,265 | 19,904,268 | BACKGROUND
No standard treatment for locally advanced pancreatic cancer (LAPC) is defined.
PATIENTS AND METHODS
Within a multi-centre, randomised phase II trial, 95 patients with LAPC were assigned to three different chemoradiotherapy (CRT) regimens: patients received conventionally fractionated radiotherapy of 50 ... | 0no significant effect |
4,768,887 | 26,955,283 | BACKGROUND
Fluorodeoxyglucose-positron emission tomography (PET)/computed tomography (CT) is reported to have a significant advantage over CT for staging esophageal cancer (EC). However, whether PET/CT may play a useful role in guiding surgical approach remains undetermined.
METHODS
Patients with potentially resect... | 0no significant effect |
4,320,136 | 25,660,254 | BACKGROUND
Banana is a staple food in many regions with high iron deficiency and may be a potential vehicle for iron fortification. However, iron absorption from bananas is not known.
OBJECTIVE
The objective of this study was to evaluate total iron absorption from raw and cooked bananas.
DESIGN
Thirty women (34.9... | 1significant effect |
4,544,133 | 26,311,995 | OBJECTIVES
To compare anti-inflammatory effect of atorvastatin and rosuvastatin in patients of acute coronary syndrome.
MATERIALS AND METHODS
The study was a prospective, open-labeled, randomized and single-center study conducted on 100 patients of acute coronary syndrome. Patients were assigned to atorvastatin 40 ... | 1significant effect |
4,685,630 | 26,691,535 | BACKGROUND
Autism is associated with impairments that have life-time consequences for diagnosed individuals and a substantial impact on families. There is growing interest in early interventions for children with autism, yet despite the substantial economic burden, there is little evidence of the cost-effectiveness o... | 1significant effect |
4,234,827 | 25,358,451 | INTRODUCTION
We investigated the potential benefits of early tracheotomy performed before day eight of mechanical ventilation (MV) compared with late tracheotomy (from day 14 if it still indicated) in reducing mortality, days of MV, days of sedation and ICU length of stay (LOS).
METHODS
Randomized controlled trial ... | 1significant effect |
3,704,267 | 23,802,809 | BACKGROUND
Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). But a fewer smoking cessation measures were conducted in communities for smokers with COPD in China. The aim of our study was to assess the preventive effects of behavioral interventions for smoking cessation and p... | 1significant effect |
5,149,084 | 27,957,263 | BACKGROUND
The underlying etiology of recurrent aphthous stomatitis (RAS) is unclear and treatment aims to provide symptomatic and faster relief. This study compared the efficacy of diode laser, a herbal combination of Acacia nilotica and Licorice (A and L) and Amlexanox in the management of RAS.
MATERIAL AND METHODS... | 1significant effect |
4,832,354 | 26,195,199 | BACKGROUND
Patient decision aids (P-DAs) inform medical decision making, but longer term effects are unknown. This article describes extended follow-up from a thyroid cancer treatment P-DA trial.
METHODS
In this single-center, parallel-design randomized controlled trial conducted at a Canadian tertiary/quaternary c... | 1significant effect |
3,877,023 | 24,391,767 | BACKGROUND
The purpose of the present study was to compare the image quality of spinal magnetic resonance (MR) imaging performed on a high-field horizontal open versus a short-bore MR scanner in a randomized controlled study setup.
METHODS
Altogether, 93 (80% women, mean age 53) consecutive patients underwent spine... | 1significant effect |
5,768,344 | 29,371,927 | INTRODUCTION
Although pharmacogenomics has evolved substantially, a predictive test for chemotherapy toxicity is still lacking. We compared the toxicity of adjuvant dose-dense doxorubicin-cyclophosphamide (ddAC) and docetaxel-doxorubicin-cyclophosphamide (TAC) in a randomized multicenter phase III trial and replicate... | 1significant effect |
5,158,040 | 27,977,774 | INTRODUCTION
Diastolic dysfunction is an important predictor of poor outcome after myocardial infarction. Metformin treatment improved diastolic function in animal models and patients with diabetes. Whether metformin improves diastolic function in patients presenting with ST-segment elevation myocardial infarction (S... | 0no significant effect |
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