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BacDive Genomes with Phenotype Annotations

This dataset bundles bacterial genomes downloaded from NCBI (linked to BacDive strain records) together with the BacDive phenotypic metadata — providing a paired genome ↔ phenotype resource for bacterial trait prediction.

Contents

File Size Description
genome_download.zip 27.3 GB (~91 GB unzipped, 21,069 files) NCBI Datasets package with 21,461 bacterial genomes in FASTA. Includes assembly_data_report.jsonl (NCBI metadata) and dataset_catalog.json
gca_list.txt 280 KB List of all 20,486 GCA accessions submitted to NCBI download
bacdive_merged.csv 9.3 MB 99,392 BacDive entries spanning 22,840 unique species with phenotypic features

Genome Assembly Statistics

Computed from assembly_data_report.jsonl (21,461 genomes):

Metric Min Median Mean Max
Total sequence length (bp) 54,895 4,142,744 4,457,843 16,040,666
Number of contigs 1 37 104 11,539
Contig N50 (bp) 567 312,410 1,275,268 16,040,666
GC content (%) 22.5 56.0 53.0 77.0

Assembly level breakdown:

Level Count %
Contig 10,377 48%
Scaffold 6,848 32%
Complete Genome 3,836 18%
Chromosome 400 2%

Phenotype Feature Coverage (bacdive_merged.csv)

Coverage = fraction of the 99,392 BacDive entries that have a non-empty value.

Feature Coverage Notes
is_type_strain_header 100.0% All entries flagged
Temperature 49.8% Growth temperature (range/single value)
Oxygen tolerance 29.1% aerobe / anaerobe / facultative / microaerophile
Gram stain 22.8% positive / negative / variable
Motility 16.8% 0/1 binary
Cell shape 15.3% rod / coccus / oval / filament / spiral
Ability of spore formation 14.6% 0/1 binary
pH 6.8% Growth pH
Cell length 6.0% μm
Cell width 5.9% μm
Pathogenicity (animal) 2.3% 0/1 binary
Pathogenicity (human) 1.6% 0/1 binary
Pathogenicity (plant) 0.4% 0/1 binary

Top categorical values

Gram stain: negative (14,236) > positive (8,360) > variable (67) Cell shape: rod-shaped (11,928) > coccus-shaped (1,845) > oval (584) > ovoid (372) > filament (104) > spiral (67) Oxygen tolerance: aerobe (10,610) > obligate aerobe (5,360) > anaerobe (5,153) > microaerophile (3,785) > facultative anaerobe (3,769) Motility (1=motile): 0 = 11,076, 1 = 5,668 Spore formation (1=can form): 0 = 11,592, 1 = 2,957

Full column list (24 cols)

Category Features
Identity ID (BacDive ID), species, designation_header, strain_number_header (DSM/ATCC/etc.), is_type_strain_header
Morphology Cell shape, Gram stain, Motility, Cell length, Cell width
Growth conditions Temperature, pH
Physiology Oxygen tolerance (obligate aerobe / anaerobe / facultative / microaerophile), Ability of spore formation
Pathogenicity Pathogenicity (human), Pathogenicity (animal), Pathogenicity (plant)

Example row

Field Value
ID 219
species Abiotrophia defectiva
strain_number_header DSM 9849, ATCC 49176, CIP 103242, SC 10, CCUG 27639
is_type_strain_header 1
Cell shape coccus-shaped
Gram stain positive
Motility 0.0
Temperature 25-41
Ability of spore formation 0.0
Oxygen tolerance anaerobe

Note: Some columns appear duplicated (Cell shape, Gram stain, Motility, Cell length, Cell width, Temperature) — this is an artifact of an upstream join. Either copy can be used.

Genome ↔ Phenotype Linkage

The CSV does not contain a direct GCA accession column. To link a genome to its BacDive entry, join via:

  • Strain designation: match strain_number_header (e.g. "DSM 9849") to the genome's strain in assembly_data_report.jsonl
  • Species name: match species to NCBI organism (less precise — same species often has many strains)
  • NCBI taxonomy ID: BacDive entries include NCBI tax id (in original BacDive JSON) → matchable against NCBI assembly metadata

Source

  • Genomes: Downloaded from NCBI Datasets API (ncbi datasets download genome accession ...) on 2025-04-11
  • Phenotype data: BacDive (https://bacdive.dsmz.de/) — Bacterial Diversity Metadatabase, operated by DSMZ
  • Genome list: Derived from BacDive strain records with available type-strain or representative NCBI assemblies

Citation

If you use this dataset, please cite BacDive:

Reimer, L.C., Sardà Carbasse, J., Koblitz, J., et al. BacDive in 2022: the bacterial diversity metadatabase in 2022. Nucleic Acids Research 50(D1): D741-D746 (2022). https://doi.org/10.1093/nar/gkab961

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