Datasets:
Scent of Health (S-O-H) Dataset
Overview
The Scent of Health (S-O-H) dataset is the largest public clinical electronic nose (eNose) collection for non-invasive disease screening via exhaled breath analysis. It comprises 1,234 patients across eight diagnostic groups (healthy controls and seven diseases), each providing a 17-channel multivariate time series of breath measurements.
| Property | Value |
|---|---|
| Patients | 1,234 |
| Diagnostic groups | 9 (healthy + 8 diseases) |
| Time series channels | 17 (eNose sensors) + auxiliary sensors |
| Sampling rate | 0.4 Hz |
| Duration per sample | 895 seconds (~15 minutes) |
| Collection period | 13 consecutive weeks |
| Clinical sites | 2 |
Repository Structure
S-OH/
├── README.md # This file
├── LICENSE.txt # MIT License
├── metadata.csv # Patient metadata (demographics, diagnosis, site, week)
├── data/
│ ├── manifest.json # Index of all patient files
│ ├── Z00/ # Healthy controls
│ │ ├── patient_1.json
│ │ ├── patient_2.json
│ │ └── ...
│ ├── B18/ # Hepatitis B/C
│ │ ├── patient_10.json
│ │ └── ...
│ ├── K29/ # Gastritis and duodenitis
│ ├── K76/ # Non-alcoholic fatty liver disease
│ ├── E11/ # Diabetes mellitus type II
│ ├── N18/ # Chronic renal failure
│ ├── J44/ # COPD
│ ├── C34/ # Lung cancer
│ └── A15/ # Respiratory tuberculosis
└── scripts/
├── quick_start.py # Load metadata and patient JSONs
├── validate_metadata.py # Metadata check
├── validate_temporal_splits.py # Temporal splits check
├── baseline_lstm_lung_cancer.py # Example: ML/AI Use Case (LSTM baseline for C34)
├── baseline_cnn_z00.py # Temporal splits check
└── baseline_resnet18_z00.py # Example: ML/AI Use Case (LSTM baseline for C34)
Dataset Structure
metadata.csv
CSV file containing patient metadata with the following columns:
| Column | Description |
|---|---|
Patient_id |
Unique patient identifier |
Patient_age |
Age in years |
Patient_gender |
Gender (0 = female, 1 = male) |
Diagnosis |
ICD-10 diagnosis code |
D_class |
Disease class (0–7) |
D_bin_class |
Binary class for one-vs-rest classification |
Datetime |
Collection timestamp |
Week |
Collection week (1–13) |
Site |
Clinical site (SiteA or CiteB) |
data/ - Per-Patient JSON Files
Each patient is stored as a separate JSON file in a subdirectory named after their ICD-10 diagnosis code. The file name format is patient_{Patient_id}.json. Example path: data/Z00/patient_1.json.
Each patient JSON file has the following structure:
{
"patient_id": 1,
"patient_diag_class": 0,
"startDateTime": "2025-09-01T08:05:47.676148Z",
"startTimeGases": 20,
"endTimeGases": 450,
"durationSec": 895,
"sensors": [
{
"id": "enose",
"sampleRate": 0.4,
"channels": [
{"id": "R1", "samples": [float, ...]},
{"id": "R2", "samples": [float, ...]},
...
{"id": "R17", "samples": [float, ...]},
{"id": "humidity", "samples": [float, ...]},
{"id": "temperature", "samples": [float, ...]}
]
},
{
"id": "ze03",
"sampleRate": 0.4,
"channels": [{"id": "0", "samples": [float, ...]}]
},
{
"id": "mhz14",
"sampleRate": 0.4,
"channels": [{"id": "0", "samples": [float, ...]}]
},
{
"id": "ze08",
"sampleRate": 0.4,
"channels": [{"id": "0", "samples": [float, ...]}]
},
{
"id": "bme280",
"sampleRate": 0.4,
"channels": [
{"id": "pressure", "samples": [float, ...]},
{"id": "temperature", "samples": [float, ...]},
{"id": "humidity", "samples": [float, ...]}
]
}
]
}
data/manifest.json
Index file mapping patient IDs to their JSON file paths:
{
"total_patients": 1234,
"files": [
{"patient_id": 1, "diagnosis": "Z00", "file": "Z00/patient_1.json"},
{"patient_id": 2, "diagnosis": "Z00", "file": "Z00/patient_2.json"},
...
]
}
scripts/
Utility scripts for loading and processing the dataset.
eNose Channels (17 channels)
The eNose sensor array consists of 17 channels printed on a single chip:
| Channel ID | Material |
|---|---|
| R1–R17 | ZnO and metal-doped ZnO (In-ZnO, Ag-ZnO, Ce-ZnO, Ni-ZnO) |
Auxiliary Sensors
| Sensor ID | Measurements |
|---|---|
| ze03 | Ozone (O₃) |
| mhz14 | Carbon dioxide (CO₂) |
| ze08 | Carbon monoxide (CO) |
| bme280 | Pressure, temperature, humidity |
Quick Start
import json
import pandas as pd
# 1. Load metadata
metadata = pd.read_csv('../metadata.csv')
# 2. Load patient data via manifest
with open('../data/manifest.json', 'r') as f:
manifest = json.load(f)
# 3. Load a specific patient
patient_id, icd = '1', 'Z00'
entry = next(e for e in manifest['files'] if e['patient_id'] == patient_id)
with open(f"../data/{icd}/{entry['file']}", 'r') as f:
patient_data = json.load(f)
# 4. Extract eNose signals
for sensor in patient_data['sensors']:
if sensor['id'] == 'enose':
for channel in sensor['channels']:
print(f"{channel['id']}: {len(channel['samples'])} samples")
Temporal Train/Test Splits
The dataset includes explicit temporal splits to enable drift-aware evaluation. For each disease, test weeks were selected to be temporally separated from training weeks, simulating real-world deployment conditions.
Ethics
The study protocol was approved by the Local Ethics Committee at Anonymized Clinical Institute (SiteA) and Anonymized Research Institute (SiteB).
All participants provided written informed consent.
Citation
If you use this dataset in your research, please cite:
@article{soh2026,
title = {Scent of Health (S-OH): Olfactory Multivariate Time Series Dataset for Non-Invasive Disease Screening},
author = {Anonymized and ...},
journal = {MICCAI Open Data},
year = {2026}
}
License
This dataset is released under the MIT License. See LICENSE.txt for full terms. You are free to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the dataset, subject to the condition that the copyright notice and permission notice are included in all copies or substantial portions.
Contact
For questions or issues, please open an issue on this repository or contact the corresponding author (see paper for details).