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clear ;
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clc;
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close all;
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savedir='D:\Project_EEG_CC\CC_Results_step2_AllChannels_NEW\';
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cd(savedir);
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load('D:\Project_EEG_CC\mFiles\ONOFF.mat','ONOFF')
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load('D:\Project_EEG_CC\mFiles\BV_Chanlocs_60.mat');
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PDsx=[801:811,813:829];
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CTLsx=[8010,8070,8060,890:914];
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BigN=size(ONOFF,1)./2;
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% load PD OFF and ON data
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row=1;
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for mi=1:size(ONOFF,1)
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disp([num2str(ONOFF(mi,1)),'_Session_',num2str(ONOFF(mi,2)),'_PDDys_CC_ALL_GOODS.mat']);
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if ONOFF(mi,1)==824 && ONOFF(mi,2)==2 % Bad EEG
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VECTOR=NaN; ERPs=NaN(size_erp); POWER=NaN(size_power);
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else
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load([savedir,num2str(ONOFF(mi,1)),'_Session_',num2str(ONOFF(mi,2)),'_PDDys_CC_ALL_GOODS.mat']);
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size_erp=size(ERPs); size_power=size(POWER);
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end
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if ONOFF(mi,3)==1 % ON
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ON.ID(floor(row))=ONOFF(mi,1);
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ON.Session(floor(row))=ONOFF(mi,2);
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ON.ERPs(floor(row),:,:,:,:)=ERPs;
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ON.POWER{1}(floor(row),:,:,:,:,:)=POWER;
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elseif ONOFF(mi,3)==0 % OFF
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OFF.ID(floor(row))=ONOFF(mi,1);
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OFF.Session(floor(row))=ONOFF(mi,2);
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OFF.ERPs(floor(row),:,:,:,:)=ERPs;
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OFF.POWER{1}(floor(row),:,:,:,:,:)=POWER;
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end
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row=row+.5;
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clear ERPs Model_Output POWER ITPC;
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end
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% load control data
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row=1;
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for CTLi=CTLsx;
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disp([num2str(CTLi),'_Session_1_PDDys_CC_ALL_GOODS.mat']);
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if ONOFF(mi,1)==911 && ONOFF(mi,2)==1 % Bad EEG
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VECTOR=NaN; ERPs=NaN(size_erp); POWER=NaN(size_power);
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else
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load([savedir,num2str(CTLi),'_Session_1_PDDys_CC_ALL_GOODS.mat']);
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end
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CTL.ID(floor(row))=CTLi;
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CTL.Session(floor(row))=1;
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CTL.ERPs(floor(row),:,:,:,:)=ERPs;
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CTL.POWER{1}(floor(row),:,:,:,:,:)=POWER;
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row=row+1;
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clear ERPs Model_Output POWER;
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end
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CtlN=row-1;
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%% % ######################## Response - locked ERPs #################
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tx2disp=-500:2:1000;
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CHAN=21; % Cz
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paneli = 2; % response
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%%%% for Control
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subplot(321)
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shadedErrorBar2(tx2disp,squeeze(nanmean(CTL.ERPs(:,CHAN,:,1,paneli),1)),squeeze(nanstd(CTL.ERPs(:,CHAN,:,1,paneli),1))./sqrt(28),'lineprops','b');hold on
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plot(tx2disp,squeeze(nanmean(CTL.ERPs(:,CHAN,:,1,paneli),1)),'b','linewidth',2); hold on
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shadedErrorBar2(tx2disp,squeeze(nanmean(CTL.ERPs(:,CHAN,:,2,paneli),1)),squeeze(nanstd(CTL.ERPs(:,CHAN,:,2,paneli),1))./sqrt(28),'lineprops','c');hold on
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plot(tx2disp,squeeze(nanmean(CTL.ERPs(:,CHAN,:,2,paneli),1)),'c','linewidth',2); hold on
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plot([0 0],[-5 10],'k:'); title(' Control: Cz');hold off; box off; ylim([-3 8]);
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%%%% for PD ON
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subplot(323)
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shadedErrorBar2(tx2disp,squeeze(nanmean(ON.ERPs(:,CHAN,:,1,paneli),1)),squeeze(nanstd(ON.ERPs(:,CHAN,:,1,paneli),1))./sqrt(28),'lineprops','r');hold on
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plot(tx2disp,squeeze(nanmean(ON.ERPs(:,CHAN,:,1,paneli),1)),'r','linewidth',2); hold on
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shadedErrorBar2(tx2disp,squeeze(nanmean(ON.ERPs(:,CHAN,:,2,paneli),1)),squeeze(nanstd(ON.ERPs(:,CHAN,:,2,paneli),1))./sqrt(28),'lineprops','m');hold on
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plot(tx2disp,squeeze(nanmean(ON.ERPs(:,CHAN,:,2,paneli),1)),'m','linewidth',2); hold on
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plot([0 0],[-5 10],'k:'); title('PD ON: Cz');hold off; box off; ylim([-3 8]);
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% % % ################## Time Frequency #####################
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tx2disp=-500:2:1000;
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frex=logspace(.01,1.7,50);
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Bidx=1; % 1 is pre-cue baseline
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CHANI=21; % Cz
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EVENT=2; % RESP
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%%%%%%%%%%%%%%%%%%%%%%%%% %%% figure for PD OFF/ON - Control
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CTL_Conf2 = CTL.POWER{Bidx}(:,CHANI,:,:,2,EVENT); CTL_Conf1 = CTL.POWER{Bidx}(:,CHANI,:,:,1,EVENT);
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ON_Conf2 = ON.POWER{Bidx}(:,CHANI,:,:,2,EVENT); ON_Conf1 = ON.POWER{Bidx}(:,CHANI,:,:,1,EVENT);
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CTL_Conf12 = (squeeze( nanmean(CTL_Conf2,1)) + squeeze( nanmean(CTL_Conf1,1)))/2;
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PD_ON_Conf12 = (squeeze( nanmean(ON_Conf2,1)) + squeeze( nanmean(ON_Conf1,1)))/2;
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CTL_Conf21 = squeeze( nanmean(CTL_Conf2,1)) - squeeze( nanmean(CTL_Conf1,1));
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PD_ON_Conf21 = squeeze( nanmean(ON_Conf2,1)) - squeeze( nanmean(ON_Conf1,1));
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% %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% CONTOL and PD ON %%%%%%%%%%%%%%%%%%%%
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%%% CTL-PD ON
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subplot(322);
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imagesc( tx2disp,[], (CTL_Conf12) - (PD_ON_Conf12) ); axis xy; hold on; colormap jet
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[Corrected_P] = Run_Thresh_2D( (squeeze(ON_Conf1)+squeeze(ON_Conf2))/2, (squeeze(CTL_Conf1)+ squeeze(CTL_Conf2))/2, 'between') ;
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contour(tx2disp,1:50,Corrected_P,'k','linewidth',2); clear Corrected_P;
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plot([0 0],[1 50],'k:')
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set(gca,'clim',[-2 2],'xlim',[-500,1000],'ylim',[1 50],'YTick',1:4:length(frex),'YTickLabel',round(frex(1:4:end)));title('CTL-ON (Avg of Correct and Error)');hold off; %colorbar;
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subplot(324);
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imagesc(tx2disp,[], CTL_Conf21 - PD_ON_Conf21); axis xy; hold on; colormap jet
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[Corrected_P] = Run_Thresh_2D( squeeze(ON_Conf2)-squeeze(ON_Conf1), squeeze(CTL_Conf2)- squeeze(CTL_Conf1), 'between') ;
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contour(tx2disp,1:50,Corrected_P,'k','linewidth',2); clear Corrected_P;
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rectangle('Position',[-200 18 250 9],'EdgeColor','b','LineWidth', 3);
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plot([0 0],[1 50],'k:')
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set(gca,'clim',[-2 2],'xlim',[-500,1000],'ylim',[1 50],'YTick',1:4:length(frex),'YTickLabel',round(frex(1:4:end)));hold off; title('CTL-ON (Error-Correct)');
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% % % ####################### TOPO ######################################
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tx1 = find (tx2disp==-200); tx2 = find (tx2disp==50);
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% fq1 = min(find(frex>3)); fq2 = min(find(frex>5));
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fq1 = min(find(frex>3.8)); fq2 = min(find(frex>7.8));
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for n = 1:28
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for Chanl = 1:60
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CTL_PowCg = CTL.POWER{1}(n,Chanl,(fq1:fq2),(tx1:tx2),1,paneli); ON_PowCg = ON.POWER{1} (n,Chanl,(fq1:fq2),(tx1:tx2),1,paneli);
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CTL_PowIncg = CTL.POWER{1}(n,Chanl,(fq1:fq2),(tx1:tx2),2,paneli); ON_PowIncg = ON.POWER{1} (n,Chanl,(fq1:fq2),(tx1:tx2),2,paneli);
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%%%% Incong and Cong ....
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IngPow_CTL = squeeze(nanmean(CTL_PowIncg)); CogPow_CTL = squeeze(nanmean(CTL_PowCg));
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IngPow_ON = squeeze(nanmean(ON_PowIncg)); CogPow_ON = squeeze(nanmean(ON_PowCg));
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IncongCTL(n).chans{Chanl,1} = nanmean(IngPow_CTL); CongCTL(n).chans{Chanl,1} = nanmean(CogPow_CTL);
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IncongON(n).chans{Chanl,1} = nanmean(IngPow_ON); CongON(n).chans{Chanl,1} = nanmean(CogPow_ON);
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end
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end
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IncongruentCTL = cell(28,60);CongruentCTL = cell(28,60);
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IncongruentON = cell(28,60);CongruentON = cell(28,60);
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for n = 1:28
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IncongruentCTL(n,:) = IncongCTL(n).chans ;
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CongruentCTL(n,:) = CongCTL(n).chans ;
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IncongruentON(n,:) = IncongON(n).chans ;
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CongruentON(n,:) = CongON(n).chans ;
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end
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IncongruentCTL = cell2mat(IncongruentCTL); CongruentCTL = cell2mat(CongruentCTL);
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IncongruentON = cell2mat(IncongruentON); CongruentON = cell2mat(CongruentON);
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chanlocs = BV_Chanlocs_60;
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CTL_IncongCong = (IncongruentCTL - CongruentCTL);
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ON_IncongCong = (IncongruentON - CongruentON);
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% figure
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[~,P3,~,~]=ttest2(CTL_IncongCong,ON_IncongCong); P3(P3>=.05)=NaN; P3(P3<.05)=1; P3(isnan(P3))=0;
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subplot(326); topoplot(nanmean(CTL_IncongCong-ON_IncongCong),chanlocs,'maplimits',[-0.5 0.5],'emarker2', {find(P3),'d','k',5,1}); title ('Control-PD');colormap jet; clear P3
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suptitle ('Response-locked ERPs-TF-TOPO: Conf2 and Conf1')
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