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39776043 | 2025 | 2025 | The Patterns of P53, E-Cadherin, β-Catenin, CXCR4 and Podoplanin Expression in Oral Squamous Cell Carcinoma Suggests a Hybrid Invasion Model: an Immunohistochemical Study on Tissue Microarrays.
Purpose: Oral squamous cell carcinoma (OSCC) is a significant public health challenge associated with high mortality rates pri... | 510 |
39776045 | 2025 | 2025 | Investigating the Results of One Anastomosis Gastric Bypass After Primary Metabolic and Bariatric Restrictive Procedures.
Background: Previous studies showed a high conversion rate and failure of restrictive procedures, including sleeve gastrectomy (SG), adjustable gastric banding (AGB), gastric plication (GP), and ver... | 507 |
39776044 | 2025 | 2025 | Deep Learning-Enabled Automated Quality Control for Liver MR Elastography: Initial Results.
Background: Several factors can impair image quality and reliability of liver magnetic resonance elastography (MRE), such as inadequate driver positioning, insufficient wave propagation and patient-related factors.
Purpose: To r... | 578 |
39776042 | 2025 | 2025 | Functional study of three cases with novel TBX19 variants.
Purpose: Congenital isolated adrenocorticotropic hormone deficiency (CIAD) is an autosomal recessive disorder. This study identifies novel TBX19 variants for CIAD patients, explores its possible effect mechanism at the structural, functional and protein levels,... | 469 |
39776040 | 2025 | 2025 | Role of Non-coding RNAs in Rheumatoid Arthritis and Supervision Mechanism of Chinese Medicine.
The prevalence of rheumatoid arthritis (RA) has sharply increased in recent years, posing a serious threat to human health. RA is characterized as a chronic, multisystem disease with morning stiffness and symmetric small join... | 277 |
39776036 | 2025 | 2025 | Antimicrobial Peptides Against Arboviruses: Mechanisms, Challenges, and Future Directions.
This review delves into the potential of antimicrobial peptides (AMPs) as promising candidates for combating arboviruses, focusing on their mechanisms of antiviral activity, challenges, and future directions. AMPs have shown prom... | 220 |
39776041 | 2025 | 2025 | Assessment of ICG fluorescence in identification and preservation of parathyroid glands in thyroid surgeries and correlation with postoperative parathormone and serum calcium levels.
Introduction: Intraoperative parathyroid gland (PG) localization remains challenging during thyroid surgeries, contributing to postoperat... | 506 |
39776039 | 2025 | 2025 | Xuefu Zhuyu Decoction Improves Blood-Brain Barrier Integrity in Acute Traumatic Brain Injury Rats via Regulating Adenosine.
Objective: To explore the neuroprotective effects of Xuefu Zhuyu Decoction (XFZYD) based on in vivo and metabolomics experiments.
Methods: Traumatic brain injury (TBI) was induced via a controlled... | 466 |
39776038 | 2025 | 2025 | Weight loss and body composition after compounded semaglutide treatment in a real world setting.
Introduction: Clinical trials have shown efficacy of semaglutide for weight loss, but further study is needed in less controlled environments including impacts on body composition.
Materials And Methods: This retrospective ... | 439 |
39776037 | 2025 | 2025 | Ferroelectric Optical Memristors Enabled by Non-Volatile Electro-Optic Effect.
Memristors enable non-volatile memory and neuromorphic computing. Optical memristors are the fundamental element for programmable photonic integrated circuits due to their high-bandwidth computing, low crosstalk, and minimal power consumptio... | 314 |
39776035 | 2025 | 2025 | Protective Effects of Heat-Killed Lactobacilli against Plasma-Induced Neurotoxicity in Multiple Sclerosis.
Heat-killed lactobacilli seem to have protective effects against oxidative stress and neurotoxicity. This study aimed to evaluate the antioxidant properties of specific heat-killed lactobacilli extracts and determ... | 546 |
39776034 | 2025 | 2025 | Enhancing CO2 Electroreduction to Multicarbon Products by Modulating the Surface Microenvironment of Electrode with Polyethylene Glycol.
Modulating the surface microenvironment of electrodes stands as a pivotal aspect in enhancing the electrocatalytic performance for CO2 electroreduction. Herein, we propose an innovati... | 243 |
39776033 | 2025 | 2025 | Niraparib as First-Line Maintenance Therapy in Patients with Stage III Ovarian Cancer and No Visible Residual Disease: AR1ZE Real-World Study.
Introduction: Niraparib was approved for first-line (1L) maintenance (1LM) treatment of patients with advanced epithelial ovarian cancer (EOC) following the PRIMA/ENGOT-OV26/GOG... | 653 |
39776031 | 2025 | 2025 | Protective Effect of Transient Receptor Potential Ankyrin 1 Inhibition on Renal Ischemia Reperfusion Injury in Rats.
The transient receptor potential ankyrin 1 (TRPA1) channels, characterized as nonselective cation channels with permeability to calcium ions (Ca2 +), are part of the extensive family of transient recepto... | 469 |
39776026 | 2025 | 2025 | Stimulation, regulation, and inflammaging interventions of natural compounds on nuclear factor kappa B (NF-kB) pathway: a comprehensive review.
Nuclear factor kappa B (NF-kB) is a kind of transcription factor which resides in cytoplasm of each cell and on activation, it translocates to the nucleus. It is activated by a... | 371 |
39776027 | 2025 | 2025 | Advancements in nose-to-brain drug targeting for Alzheimer's disease: a review of nanocarriers and clinical insights.
Alzheimer's disease (AD) is a type of neurodegenerative disease that describes cognitive decline and memory loss resulting in disability in movement, memory, speech etc. Which first affects the hippocam... | 282 |
39776028 | 2025 | 2025 | Olive oil and castor oil-based self-nanoemulsifying drug delivery system of flurbiprofen can relieve peripheral pain and inflammation through reduction of oxidative stress and inflammatory biomarkers: a comprehensive formulation and pharmacological insights.
Flurbiprofen (FBP) is poorly water-soluble BCS class II drug ... | 865 |
39776029 | 2025 | 2025 | Packing Engineering of Zirconium Metal-Organic Cages in Mixed Matrix Membranes for CO2/CH4 Separation.
Metal-organic cages (MOCs) have been considered as emerging zero-dimensional (0D) porous fillers to generate molecularly homogenous MOC-based membrane materials. However, the discontinuous pore connectivity and low fi... | 223 |
39776030 | 2025 | 2025 | Active Hydroxyl-Mediated Preferential Cleavage of Carbon-Carbon Bonds in Electrocatalytic Glycerol Oxidation.
Electrocatalytic glycerol oxidation reaction (GOR) to produce high-value formic acid (FA) is hindered by high formation potential of active species and sluggish C-C bond cleavage kinetics. Herein, Ni single-ato... | 386 |
39776022 | 2025 | 2025 | Hypertrophic cardiomyopathy: insights into pathophysiology and novel therapeutic strategies from clinical studies.
Background: Hypertrophic cardiomyopathy (HCM) is a frequently encountered cardiac condition worldwide, often inherited, and characterized by intricate phenotypic and genetic manifestations. The natural pro... | 379 |
39776024 | 2025 | 2025 | From stones to sketches: investigating tracing behaviours in Japanese macaques.
The use of complex technologies by humans (Homo sapiens) and their ancestors is a key feature of our evolution, marked by the appearance of stone tools 3.3-million years ago. These technologies reflect cognitive complexity and an advanced u... | 188 |
39776025 | 2025 | 2025 | No Vaccine, No Organ? Ethics of Vaccine Mandates for Pediatric Transplant.
Many transplant programs worldwide are likely to impose vaccine mandates for pediatric solid organ transplant candidates; some already do. Three potential benefits that advocates invoke to justify mandates are improved patient outcomes, efficien... | 232 |
39776023 | 2025 | 2025 | Using Quantitative Bias Analysis to Adjust for Misclassification of COVID-19 Outcomes: An Applied Example of Inhaled Corticosteroids and COVID-19 Outcomes.
Background: During the pandemic, there was concern that underascertainment of COVID-19 outcomes may impact treatment effect estimation in pharmacoepidemiologic stud... | 508 |
39776020 | 2025 | 2025 | Serum Levels of Heavy Metals in Patients with Prostate Cancer: A Systematic Review and Meta-analysis.
Prostate cancer (PC) is a common malignancy among men globally. Although genetic, hormonal, and environmental factors contribute to its development, the role of heavy metals remains unclear. This study evaluated serum ... | 498 |
39776019 | 2025 | 2025 | The Lady and the Plants: Two Notions of Teleology in Agnes Arber's Philosophy of Plants.
Agnes Arber (1879-1960) was a British plant morphologist, historian of botany, and philosopher of biology. Though now largely forgotten, her work offers valuable insights into morphological as well as philosophical issues. This pap... | 293 |
39776021 | 2025 | 2025 | Biventricular dysfunction predicts mortality in ST elevation myocardial infarction patients with cardiogenic shock.
Background: The incidence of mortality in patients with cardiogenic shock due to ST elevation myocardial infarction (STEMI) remains high even with prompt reperfusion therapy. Ventricular systolic dysfunct... | 567 |
39776018 | 2025 | 2025 | HERC5/ISG15 Enhances Glioblastoma Stemness and Tumor Progression by mediating SERBP1protein stability.
Glioblastoma (GBM) is the most common malignant brain tumor, and has a low survival rate and a poor prognosis. Intensive studies of pathogenic mechanisms are essential for exploring therapeutic targets for GBM. In thi... | 475 |
39776015 | 2025 | 2025 | Increased Mineral-Associated Organic Carbon and Persistent Molecules in Allochthonous Blue Carbon Ecosystems.
Coastal wetlands contain very large carbon (C) stocks-termed as blue C-and their management has emerged as a promising nature-based solution for climate adaptation and mitigation. The interactions among sources... | 349 |
39776017 | 2025 | 2025 | Longitudinal Relations Between Emotional Abuse and Suicidal Ideation: The Mediating Role of Self-disgust Among Chinese Early Adolescents.
Previous research has consistently demonstrated that emotional abuse is a robust predictor of adolescent suicidal ideation. However, few studies have explored the bidirectional relat... | 321 |
39776016 | 2025 | 2025 | The real-world efficacy and safety of frontline therapy of obinutuzumab plus bendamustine for untreated high-tumor-burden follicular lymphoma.
Background: While R-CHOP has been one of the standard therapies for untreated high-tumor-burden (HTB) follicular lymphoma (FL) for over 2 decades, obinutuzumab plus bendamustine... | 458 |
39776011 | 2025 | 2025 | Application of genetic testing criteria for hereditary breast cancer in South Africa.
Purpose: Breast cancer (BC) is the commonest cancer in South African women. A proportion are associated with a pathogenic or likely pathogenic (P/LP) variant in a BC susceptibility gene. Clinical guidelines for genetic testing are use... | 454 |
39776014 | 2025 | 2025 | Perspectives on Clinical Pharmacist-Delivered Contingency Management to Promote Smoking Abstinence Among Individuals with HIV: A Qualitative Study.
Contingency management (CM), an evidence-based behavioral strategy that rewards positive behavior change including tobacco cessation, is rarely offered to support people wi... | 358 |
39776013 | 2025 | 2025 | Training Elite Athletes: 50 Years of Thinking About Practice and Research for Endurance Sports.
This essay summarizes and integrates my experiences and observations-starting in the middle 1970s-as an athlete, scientist interested in human performance, biomedical researcher, and "expert," who sometimes advises athletes,... | 222 |
39776012 | 2025 | 2025 | Estrogen receptor positivity in stromal cells of the tumor bed predicts the response to neoadjuvant chemotherapy for breast carcinoma.
Purpose: This study aimed to determine estrogen receptor (ER) expression in stromal cells in postchemotherapy tumor bed (PCTB) and its relationship with tumor regression and tumor chara... | 634 |
39776010 | 2025 | 2025 | circHOMER1 Alleviates Sevoflurane-Induced Hippocampal Neuronal Injury via Targeted Negative Regulation of miR-217.
Sevoflurane (Sev) is a widely applied anesthetic in clinical practice; however, it could induce neurotoxicity and lead to postoperative cognitive dysfunction (POCD). This study aimed to investigate the rol... | 398 |
39776004 | 2025 | 2025 | Environmental Dissemination of SARS-CoV-2: An Analysis Employing Crassphage and Next-Generation Sequencing Protocols.
This study aimed to investigate the dissemination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in water samples obtained during the coronavirus disease 2019 pandemic period, employing... | 422 |
39776008 | 2025 | 2025 | Clinical significance of a new early diagnostic model for bladder cancer based on genome-wide microarray profiling of serum exosomal lncRNAs.
Purpose: The aim of our report was to recognize bladder cancer (BC)-specific serum exosome-derived long non-coding RNAs (lncRNAs) profile for early diagnosis of BC.
Methods: Pote... | 486 |
39776009 | 2025 | 2025 | The prognostic value of serum testosterone to BMI ratio in Chinese males with prostate cancer treated by androgen deprivation therapy: a single-center study.
Objective: To investigate the prognostic value of serum testosterone combining with body mass index (BMI) on the prostate cancer (PCa) after androgen deprivation ... | 561 |
39776006 | 2025 | 2025 | Psychological Distress in Patients With Asbestos-Related Diseases and Their Families: A Systematic Literature Review.
Background: Exposure to asbestos in the workplace is currently recognized as one of the leading causes of work-related deaths, with more than half of deaths attributable to cancer.
Aims: The aim of this... | 336 |
39776007 | 2025 | 2025 | The assistive role of an internal fluid circulatory device in ureteroscopic lithotripsy: a randomized, controlled and prospective study.
Purpose: To evaluate and compare the efficacy of a newly designed in-house assistive internal fluid circulatory device in ureteroscopic lithotripsy for ureteral stones.
Methods: In th... | 438 |
39776001 | 2025 | 2025 | Analysis of exportins expression unveils their prognostic significance in colon adenocarcinoma: insights from public databases.
Colon cancer remains a significant health burden globally, necessitating deeper investigation. Identification and targeting of prognostic markers can significantly improve the current therapeu... | 330 |
39776002 | 2025 | 2025 | Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long-duration space travel.
Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide ( P aC O 2 ${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$ ), owi... | 416 |
39776005 | 2025 | 2025 | Cognitive Health After Cerebellar Stroke: Potential Link Between Socio-Educational Status and Memory Outcome.
While deficits in episodic memory have been noted following cerebellar damage, there is a lack of research systematically exploring the socio-demographic and cognitive profiles of patients with such impairments... | 298 |
39776003 | 2025 | 2025 | Global, regional, and national burden of malignant neoplasm of bone and articular cartilage in adults aged 65 years and older, 1990-2021: a systematic analysis based on the global burden of disease study 2021.
Background: This study aims to delineate the global, regional, and national burden of malignant neoplasms of b... | 501 |
39776000 | 2025 | 2025 | Do P-glycoprotein-mediated drug-drug interactions at the blood-brain barrier impact morphine brain distribution?
P-glycoprotein (P-gp) is a key efflux transporter and may be involved in drug-drug interactions (DDIs) at the blood-brain barrier (BBB), which could lead to changes in central nervous system (CNS) drug expos... | 385 |
39775999 | 2025 | 2025 | Kalubustrongylus arsoensis gen. et sp. n. (Trichostrongylidae: Filarinematinae) and Other Nematodes Belonging to the Suborder Trichostrongylina Parasitic in the Common Spiny Bandicoot, Echymipera kalubu, of Papua Indonesia.
Purpose: The present paper reports the nematodes of the suborder Trichostrongylina collected fro... | 450 |
39775998 | 2025 | 2025 | Mechanical Cell Interactions on Curved Interfaces.
We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models of flat epithelia to investi... | 291 |
39775997 | 2025 | 2025 | Outcome of follow-up computed tomography of suspected occult scaphoid fracture after normal radiography.
Purpose: To evaluate the rate of missed scaphoid fractures on follow-up computed tomography (CT) for suspected occult scaphoid fracture after normal radiography with residual radial-sided wrist pain.
Methods: In a r... | 301 |
39775996 | 2025 | 2025 | Data Analysis Methods in Time-Resolved Fluorescence Spectroscopy: A Tutorial Review.
Fluorescence spectroscopy and related techniques benefit from exceptional sensitivity and have become engrained in a variety of fields from biosciences to materials sciences. Measuring time-domain fluorescence decays is nowadays a rout... | 240 |
39775993 | 2025 | 2025 | Ginkgo biloba extract mediates HT22 cell proliferation and migration after oxygen-glucose deprivation/reoxygenation via regulating RhoA-ROCK2 signalling pathway.
Vascular dementia (VD) is a neurocognitive disorder resulting from cerebral vascular disorders, leading to the demise of neurons and cognitive deficits, posin... | 374 |
39775994 | 2025 | 2025 | Success of the German Cystic Fibrosis Registry.
The German Cystic Fibrosis (CF) Registry (GCFR) is a national General Data Protection Regulation-compliant centralised database sponsored by the German Cystic Fibrosis Association (Mukoviszidose e.V.) and based on informed consent for each participating patient, ethical a... | 313 |
39775995 | 2025 | 2025 | First Step on the Way to Identify Dermatophytes Using Odour Fingerprints.
The clinical diagnosis of dermatophytosis and identification of dermatophytes face challenges due to reliance on culture-based methods. Rapid, cost-effective detection techniques for volatile organic compounds (VOCs) have been developed for other... | 320 |
39775991 | 2025 | 2025 | LncRNA-miRNA-mRNA regulatory axes as potential biomarkers in cervical cancer: a comprehensive overview.
Despite the recent advances in vaccination and treatment strategies, cervical cancer continues to claim numerous lives every year. Owing to the fact that non-coding RNAs (ncRNAs) such as long non-coding RNAs (lncRNAs... | 228 |
39775988 | 2025 | 2025 | Vitamin A and its influence on tumour extracellular matrix.
Vitamin A is a crucial nutrient renowned for its role in visual health and cellular regulation. Its derivatives influence cell differentiation, proliferation, and tissue homeostasis, making them significant in cancer research due to their effects on both norma... | 218 |
39775990 | 2025 | 2025 | Subcortical Maternal Complex in Female Infertility: A Transition from Animal Models to Human Studies.
Female infertility is a significant healthcare burden that is frequently encountered among couples globally. While environmental factors, comorbidities, and lifestyle determine reproductive health, certain genetic vari... | 316 |
39775987 | 2025 | 2025 | Aroeira (Myracrodruon urundeuva) and Malva (Herissantia crispa) have forage potential for ruminant nutrition in arid regions.
The Caatinga biome has a wide variety of plants which, despite their irregular distribution, are frequently used to feed animals. This study aimed to evaluate the gas production kinetics of Caat... | 374 |
39775989 | 2025 | 2025 | Manganese Galvanic Cells Intervene in Tumor Metabolism to Reinforce cGAS-STING Activation for Bidirectional Synergistic Hydrogen-Immunotherapy.
The cGAS-STING pathway is pivotal in initiating antitumor immunity. However, tumor metabolism, particularly glycolysis, negatively regulates the activation of the cGAS-STING pa... | 342 |
39775986 | 2025 | 2025 | Amyloidosis and Heart Transplantation in a New Era.
Background: The prognosis in patients with advanced cardiac amyloidosis (CA) remains poor.
Objectives: We sought to describe survival post heart transplantation (HT) in amyloid compared with non-amyloid recipients, highlight waitlist times within the new allocation sy... | 463 |
39775984 | 2025 | 2025 | PRMT1-mediated BRD4 arginine methylation and phosphorylation promote partial epithelial-mesenchymal transformation and renal fibrosis.
Bromodomain-containing protein 4 (BRD4) plays a vital role in fibrosis of various organs. However, the underlying mechanism of BRD4 in renal fibrosis remains unclear. To construct in vi... | 420 |
39775981 | 2025 | 2025 | Evaluating the Immunoprotective and Diagnostic Potential of Schistosoma mansoni Epitopes from Sm050890 and Sm141290 Proteins Identified Through Reverse Vaccinology.
Purpose: Schistosomiasis remains a parasitic disease affecting millions of people worldwide, requiring interventions like vaccination. In previous work, ou... | 467 |
39775982 | 2025 | 2025 | Comparative assessment of chondral defect repair using human bone marrow- and adipose tissue-derived mesenchymal stem cells, adult and foetal articular cartilage-derived chondrocytes, and chondroprogenitors: an ex-vivo model.
Purpose: Cartilage repair necessitates adjunct therapies such as cell-based approaches, which ... | 481 |
39775985 | 2025 | 2025 | Geometric Effects on C-C Coupling of Aryl-Carbenes under 2D Confinement.
It is well established that the confinement of reactants to two dimensions influences their reactivity. However, such confinement is often dominated by charge transfer effects between the reactants and the confining walls, in particular if the wal... | 273 |
39775983 | 2025 | 2025 | Piezochromic Luminescence of Pyrene Derivatives Polymorphism around Excimer Forming Processs.
Pyrene aggregates, as classic luminescent materials, are of great interest from a scientific viewpoint owing to the development of optoelectronic materials. In this study, we designed a compound 1,4,5-triphenyl-2-(pyren-1-yl)-... | 287 |
39775979 | 2025 | 2025 | Identification of the novel BRCA1 c.2463_2464delTA mutation in two high grade serous ovarian cancer sisters and potential dosage effects implications: a case report.
Background: Ovarian Cancer is one of the leading causes of cancer death among women worldwide and the therapeutic landscape to treat it is constantly evol... | 250 |
39775977 | 2025 | 2025 | Evolutionary Analysis of Hypoderma Pantholopsum in Tibetan Antelopes on the Qinghai-Tibetan Plateau.
Purpose: Hypoderma pantholopsum is a parasite that parasitizes Tibetan antelopes (Pantholops hodgsonii). This study aims was to reveal the genetic diversity within H. pantholopsum and contribute to the protection of Tib... | 373 |
39775978 | 2025 | 2025 | Metabolic syndrome is associated with breast cancer mortality: A systematic review and meta-analysis.
Background: This systematic review and meta-analysis assesses the association between metabolic syndrome and breast cancer (BC) outcomes in BC survivors.
Methods: Systematic searches were carried out in PubMed and Emba... | 396 |
39775980 | 2025 | 2025 | One Step Synthesis of 4,6,8-Trimethoxyazulenes - a General Building Block for 2-Functionalized Azulenes.
Here we present a simple gold-catalyzed one-pot reaction of easily available diarylbutadiynes, with trimethoxybenzene as solvent and reactant to synthesize 4,6,8-trimethoxyazulenes. The methoxy substituents, which r... | 185 |
39775975 | 2025 | 2025 | Synthesis and characterisation of DOTA-kisspeptin-10 as a potential gallium-68/lutetium-177 pan-tumour radiopharmaceutical.
Kisspeptin (KISS1) and its cognate receptor (KISS1R) are implicated in the progression of various cancers. A gallium-68 labelled kisspeptin-10 (KP10), the minimal biologically active structure, ha... | 412 |
39775973 | 2025 | 2025 | Congenital goiter in an alpaca (Vicugna pacos) fetus concomitant with brain pathology in the dam: composing the puzzle.
This study describes the congenital goiter in an alpaca (Vicugna pacos) fetus aborted in November 2021 with the clinical and pathological findings in the dam that was found dead on the farm three week... | 398 |
39775974 | 2025 | 2025 | Effect of education program regarding pathological jaundice on nurses' performance and neonates' bilirubin-induced neurological dysfunction.
Both term and preterm infants are susceptible to pathological jaundice, a frequent condition that can cause long-lasting neurological damage. A novel treatment for indirect pathol... | 482 |
39775969 | 2025 | 2025 | Mutant Calreticulin in MPN: Mechanistic Insights and Therapeutic Implications.
Purpose Of Review: More than a decade following the discovery of Calreticulin (CALR) mutations as drivers of myeloproliferative neoplasms (MPN), advances in the understanding of CALR-mutant MPN continue to emerge. Here, we summarize recent a... | 274 |
39775970 | 2025 | 2025 | Value driven outcome (VDO) assessment for the treatment of olecranon fractures.
Purpose: Controversy remains about the ideal construct for certain olecranon fractures. The purpose of this study was to compare cost-effectiveness with the value driven outcomes tool between fixation strategies of olecranon fractures.
Meth... | 415 |
39775972 | 2025 | 2025 | A Novel Isotropic Optical Fiber: Antimicrobial Effect of Blue Light on Drug Resistant Organisms.
Drug-resistant organisms (DROs) necessitate the development of new therapies. Antimicrobial blue light (ABL) is a promising option, utilizing photoexcitation of endogenous bacterial components to generate reactive oxygen sp... | 555 |
39775971 | 2025 | 2025 | Molecular detection of the zoonotic trematode Centrocestus formosanus (Nishigori, 1924) (Opisthorchiida, Heterophyidae) in Central Europe.
In our study, fancy southern platyfish Xiphophorus maculatus (Cyprinodontiformes, Poeciliidae) were examined due to breathing disorders and mortality. Fish came from Vietnam farm an... | 256 |
39775967 | 2025 | 2025 | Luminescent Cu nanoclusters-encapsulated ZIF-8 as on-off-on fluorescent probe for efficient and selective quantification of E. coli.
Rapid and accurate detection of Escherichia coli (E. coli) is critical for maintaining water quality, and protecting aquatic ecosystems and public health. This research focuses on the dev... | 433 |
39775965 | 2025 | 2025 | Is surgical treatment better than non-surgical treatment for proximal humeral fracture in elderly people? A meta-analysis and meta-regression.
Purpose: This systematic review, meta-analysis, and meta-regression aims to determine whether surgical treatment for proximal humeral fractures is superior to non-surgical treat... | 715 |
39775966 | 2025 | 2025 | AIE-active Circularly Polarized Thermally Activated Delayed Fluorescence Emitters for Stable Solution-Processed Circularly Polarized Electroluminescence.
Circularly polarized organic light-emitting diodes (CP-OLEDs) have significant promise for naked-eye 3D displays. However, most devices are fabricated using vacuum de... | 326 |
39775962 | 2025 | 2025 | The efficacy of lavender oil on fatigue and sleep quality in patients with hematological malignancy receiving chemotherapy: a single-blind randomized controlled trial.
Purpose: The aim of this study is to evaluate how aromatherapy with the inhalation of lavender oil affects fatigue and sleep quality in patients with he... | 438 |
39775964 | 2025 | 2025 | Relating Photoperiod and Outdoor Temperature With Sleep Architecture in Patients With Neuropsychiatric Sleep Disorders.
While artificial light in urban environments was previously thought to override seasonality in humans, recent studies have challenged this assumption. We aimed to explore the relationship between seas... | 676 |
39775963 | 2025 | 2025 | Relationship between periodontitis and systemic diseases: A bibliometric and visual study.
To provide a comprehensive and updated mapping of observational studies assessing the relationship between periodontitis and systemic diseases through a bibliometric and visual analysis. A search was conducted using the Web of Sc... | 510 |
39775959 | 2025 | 2025 | Exploring novel inhibitors for Babesia bigemina lactate dehydrogenase: a computational structural biology perspective.
Babesia bigemina is an apicomplexan parasite responsible for causing "Texas fever" in bovines. Current treatments for bovine babesiosis are hindered by several limitations, including toxicity, insuffic... | 414 |
39775958 | 2025 | 2025 | Free Functional Muscle Transfer in Brachial Plexus Injury Patients With Subclavian Artery Injury Using Arteriovenous Loop Grafts.
Background: Free functional muscle transfer (FFMT) for brachial plexus injury (BPI) requires adequate donor arterial flow for successful anastomosis. However, concomitant BPI and subclavian ... | 429 |
39775956 | 2025 | 2025 | Impact of biologics on stoma creation and reversal in Crohn's disease: a retrospective analysis from 2007 to 2021.
Background: Trends of stoma creation at index surgery for Crohn's disease (CD) in the biologics era has not been thoroughly investigated. This study aimed to assess the impact of increasing biologics use o... | 482 |
39775955 | 2025 | 2025 | Alternative Formulations of Job Strain and Sleep Disturbances: A Longitudinal Study in the United States.
Background: Sleep disturbances are a major public health concern in the United States, leading to adverse health outcomes. In the working population, job strain has been identified as an important risk factor for s... | 371 |
39775954 | 2025 | 2025 | Derivation of Economic Values for Breeding Objective Traits of Chinese Holstein Dairy Cows Using a Bio-Economic Model.
Holstein cattle account for the largest proportion of dairy cattle in China. The current China Performance Index (CPI) consists mainly of production traits. To derive economic values (EV) of additional... | 508 |
39775953 | 2025 | 2025 | Low readmission rates during neonatal homecare: Gestational age and bronchopulmonary dysplasia as key predictors.
Aim: Homecare for neonates has advanced, but combative analysis of contact methods remains unexplored. The aim was to identify predictors of readmission during homecare and to compare home visit, telemedici... | 364 |
39775952 | 2025 | 2025 | Local flap guidance for scalp reconstruction following Mohs micrographic surgery.
Keratinocyte carcinomas (KCs) are commonly located on the scalp and often treated with excision with peripheral and deep en face margin assessment (PDEMA), with Mohs micrographic surgery (MMS) being the most frequently used method. Resect... | 352 |
39775946 | 2025 | 2025 | Factors associated with therapeutic response to adalimumab in hidradenitis suppurativa: evidence from the Belgian patients of the European Registry for Hidradenitis Suppurativa (ERHS-Be).
Hidradenitis suppurativa is an inflammatory skin disease for which adalimumab is an effective treatment in just over half of cases. ... | 325 |
39775951 | 2025 | 2025 | Minimally invasive measurement of carotid artery and brain temperature in the mouse.
Purpose: Brain temperature is tightly regulated and reflects a balance between cerebral metabolic heat production and heat transfer between the brain, blood, and external environment. Blood temperature and flow are critical to the regu... | 380 |
39775948 | 2025 | 2025 | Trend analysis and cross nations inequality analysis of infectious skin diseases from 1990 to 2021.
The skin serves as a crucial barrier against microbial invasion, but breaches in this barrier can lead to infectious skin diseases (ISD). ISD, including bacterial (BSD), fungal (FSD) and viral Skin Disease (VSD), pose si... | 649 |
39775949 | 2025 | 2025 | Evaluating the readability of FDA-approved JAK inhibitor medication guides in dermatology.
Prior studies have highlighted significant challenges in the readability of patient educational materials in dermatology, which may represent a barrier to optimal treatment outcomes. As newer Janus kinase inhibitors (JAKi) gain F... | 166 |
39775947 | 2025 | 2025 | Evolution of rod bipolar cells and rod vision.
Bipolar cells are vertebrate retinal interneurons conveying signals from rod and cone photoreceptors to amacrine and ganglion cells. Bipolar cells are found in all vertebrates and have many structural and molecular affinities with photoreceptors; they probably appeared ver... | 547 |
39775945 | 2025 | 2025 | Transgenerational Reproductive and Developmental Toxicity Induced by N-Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster.
N-Nitrosodimethylamine (NDMA) is a known water disinfection byproduct (DBP) characterized as a potent hepatotoxin, promutagen, and probable human carcinogen; this is be... | 405 |
39775944 | 2025 | 2025 | Open-label evaluation of oral trehalose in patients with neuronal ceroid lipofuscinoses.
The neuronal ceroid lipofuscinoses (NCLs) are incurable pediatric neurodegenerative diseases characterized by accumulation of lysosomal material and dysregulation of autophagy. Given the promising results of treatment with trehalos... | 372 |
39775942 | 2025 | 2025 | Effect of Brochure and Audio Recordings of Testicular Cancer Stories on Testicular Self-Examination: Randomized Controlled Study.
Objectives: The aim of this study was to determine the effects of a training program based on educational brochures and audio recordings of testicular cancer (TC) stories on testicular self-... | 302 |
39775940 | 2025 | 2025 | Identification and monitoring of cell heterogeneity from plasmid recombination during limonene production.
Detecting alterations in plasmid structures is often performed using conventional molecular biology. However, these methods are laborious and time-consuming for studying the conditions inducing these mutations, wh... | 420 |
39775939 | 2025 | 2025 | Optimisation of the patient having oncological surgical through prehabilitation: a narrative review.
Introduction: Prehabilitation aims to improve physiological reserve and psychological resilience, enabling patients to better tolerate the physiological stress of major surgery, thereby reducing the risk of complication... | 341 |
39775938 | 2025 | 2025 | Assessment of respiratory function in children after kidney transplantation.
Background: Severe respiratory complications following kidney transplantation have been reported, yet remain poorly understood in the pediatric population. This study aimed to document respiratory disease in this population.
Methods: At annual... | 519 |
39775937 | 2025 | 2025 | Progression of serum creatinine and glomerular filtration rate in neonatal critical care patients during the first seven days of life.
Background: Serum creatinine and estimated glomerular filtration rate (GFR) are key indicators of kidney function.
Methods: This descriptive, retrospective study included neonatal patie... | 515 |
39775933 | 2025 | 2025 | The evaluation of the serum levels of vitamin D and interleukin-33 in children with atopic dermatitis and its association with diseases severity.
Introduction: Atopic dermatitis (AD) is a chronic inflammatory disease characterized by increased skin sensitivity to environmental elements, mediated by CD4+ T helper cells ... | 476 |
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PubMed25: A preprocessed version of the PubMed 2025 Baseline, as released by the U.S. National Library of Medicine (NLM).
The dataset consists of 27M abstracts, reconstructed from their XML records, with the title of the corresponding article prepended.
The four dataset fields are:
- id: the PubMed identifier (PMID)
- yr1: the Entrez publication year
- yr2: the PubMed publication year
- content: the reconstructed abstract
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