Datasets:
Formats:
parquet
Languages:
English
Size:
10M - 100M
Tags:
biology
chemistry
drug-discovery
clinical-trials
protein-protein-interaction
gene-essentiality
License:
| #!/usr/bin/env python3 | |
| """Run LLM-as-Judge evaluation for GE-L3 reasoning predictions. | |
| Reads GE-L3 predictions, sends through judge model, computes scores. | |
| Usage: | |
| python scripts_depmap/run_ge_l3_judge.py --judge-provider gemini --judge-model gemini-2.5-flash | |
| python scripts_depmap/run_ge_l3_judge.py --run-dir results/ge_llm/ge-l3_qwen2-5-7b-instruct_3-shot_fs0 | |
| Output per run: | |
| results/ge_llm/{run}_judged/ | |
| judge_scores.jsonl, results.json, judge_meta.json | |
| """ | |
| import argparse | |
| import json | |
| import time | |
| from datetime import datetime, timezone | |
| from pathlib import Path | |
| from negbiodb.llm_client import LLMClient | |
| from negbiodb_depmap.llm_eval import GE_L3_JUDGE_PROMPT, evaluate_ge_l3, parse_ge_l3_judge_scores | |
| PROJECT_ROOT = Path(__file__).resolve().parent.parent | |
| RESULTS_DIR = PROJECT_ROOT / "results" / "ge_llm" | |
| DATA_DIR = PROJECT_ROOT / "exports" / "ge_llm" | |
| L3_DATASET_FILE = DATA_DIR / "ge_l3_dataset.jsonl" | |
| def load_gold_records() -> list[dict]: | |
| """Load GE-L3 gold records.""" | |
| records = [] | |
| with open(L3_DATASET_FILE) as f: | |
| for line in f: | |
| records.append(json.loads(line)) | |
| return records | |
| def load_predictions(pred_path: Path) -> list[dict]: | |
| """Load predictions from JSONL.""" | |
| preds = [] | |
| with open(pred_path) as f: | |
| for line in f: | |
| preds.append(json.loads(line)) | |
| return preds | |
| def find_l3_runs(results_dir: Path) -> list[Path]: | |
| """Find all GE-L3 run directories.""" | |
| runs = [] | |
| for d in sorted(results_dir.iterdir()): | |
| if d.is_dir() and d.name.startswith("ge-l3_"): | |
| pred_file = d / "predictions.jsonl" | |
| if pred_file.exists(): | |
| runs.append(d) | |
| return runs | |
| def judge_run( | |
| run_dir: Path, | |
| gold_records: list[dict], | |
| client: LLMClient, | |
| judge_model: str, | |
| ) -> dict: | |
| """Judge all predictions in a run directory.""" | |
| gold_by_id = {rec["question_id"]: rec for rec in gold_records} | |
| predictions = load_predictions(run_dir / "predictions.jsonl") | |
| judged_dir = run_dir.parent / f"{run_dir.name}_judged" | |
| judged_dir.mkdir(parents=True, exist_ok=True) | |
| # Resume support | |
| scores_path = judged_dir / "judge_scores.jsonl" | |
| completed = {} | |
| if scores_path.exists(): | |
| with open(scores_path) as f: | |
| for line in f: | |
| rec = json.loads(line) | |
| if rec.get("scores") is not None: | |
| completed[rec["question_id"]] = rec | |
| print(f" Resume: {len(completed)} already judged") | |
| remaining = [p for p in predictions if p["question_id"] not in completed] | |
| print(f" Judging {len(remaining)} remaining of {len(predictions)} total") | |
| start_time = time.time() | |
| with open(scores_path, "a") as f: | |
| for i, pred_rec in enumerate(remaining): | |
| qid = pred_rec["question_id"] | |
| gold = gold_by_id.get(qid) | |
| if gold is None: | |
| print(f" Warning: no gold record for {qid}, skipping") | |
| continue | |
| prompt = GE_L3_JUDGE_PROMPT.format( | |
| context_text=gold.get("context_text", ""), | |
| response_text=pred_rec["prediction"], | |
| ) | |
| try: | |
| judge_response = client.generate(prompt) | |
| except Exception as e: | |
| print(f" Error judging {qid}: {e}") | |
| judge_response = f"ERROR: {e}" | |
| scores = parse_ge_l3_judge_scores(judge_response) | |
| score_rec = { | |
| "question_id": qid, | |
| "judge_response": judge_response, | |
| "scores": scores, | |
| } | |
| f.write(json.dumps(score_rec, ensure_ascii=False) + "\n") | |
| f.flush() | |
| completed[qid] = score_rec | |
| if (i + 1) % 10 == 0: | |
| elapsed = time.time() - start_time | |
| rate = (i + 1) / elapsed * 60 | |
| print(f" Progress: {i + 1}/{len(remaining)} ({rate:.1f}/min)") | |
| elapsed = time.time() - start_time | |
| print(f" Judging complete: {elapsed:.0f}s") | |
| # Aggregate — evaluate_ge_l3 expects raw judge response strings | |
| all_outputs = [] | |
| for pred_rec in predictions: | |
| qid = pred_rec["question_id"] | |
| if qid in completed and completed[qid].get("judge_response"): | |
| all_outputs.append(completed[qid]["judge_response"]) | |
| else: | |
| all_outputs.append("") | |
| metrics = evaluate_ge_l3(all_outputs) | |
| with open(judged_dir / "results.json", "w") as f: | |
| json.dump(metrics, f, indent=2) | |
| meta = { | |
| "judge_model": judge_model, | |
| "source_run": run_dir.name, | |
| "n_predictions": len(predictions), | |
| "n_judged": sum(1 for o in all_outputs if o), | |
| "elapsed_seconds": elapsed, | |
| "timestamp": datetime.now(timezone.utc).isoformat(), | |
| } | |
| with open(judged_dir / "judge_meta.json", "w") as f: | |
| json.dump(meta, f, indent=2) | |
| return metrics | |
| def main(): | |
| parser = argparse.ArgumentParser(description="Run GE-L3 LLM-as-Judge evaluation") | |
| parser.add_argument("--run-dir", type=Path, default=None) | |
| parser.add_argument("--results-dir", type=Path, default=RESULTS_DIR) | |
| parser.add_argument("--judge-provider", default="gemini", choices=["gemini", "openai", "vllm"]) | |
| parser.add_argument("--judge-model", default="gemini-2.5-flash") | |
| parser.add_argument("--api-base", default=None) | |
| parser.add_argument("--api-key", default=None) | |
| parser.add_argument("--temperature", type=float, default=0.0) | |
| parser.add_argument("--max-tokens", type=int, default=512) | |
| args = parser.parse_args() | |
| print("Loading GE-L3 gold records...") | |
| gold_records = load_gold_records() | |
| test_records = [r for r in gold_records if r.get("split") == "test"] | |
| print(f" Total: {len(gold_records)}, Test: {len(test_records)}") | |
| print(f"\nInitializing judge: {args.judge_model} ({args.judge_provider})") | |
| client = LLMClient( | |
| provider=args.judge_provider, | |
| model=args.judge_model, | |
| api_base=args.api_base, | |
| api_key=args.api_key, | |
| temperature=args.temperature, | |
| max_tokens=args.max_tokens, | |
| ) | |
| if args.run_dir: | |
| runs = [args.run_dir] | |
| else: | |
| runs = find_l3_runs(args.results_dir) | |
| print(f" Found {len(runs)} GE-L3 runs to judge") | |
| for run_dir in runs: | |
| print(f"\n=== Judging: {run_dir.name} ===") | |
| metrics = judge_run(run_dir, gold_records, client, args.judge_model) | |
| for dim in ["biological_plausibility", "pathway_reasoning", | |
| "context_specificity", "mechanistic_depth"]: | |
| key_mean = f"{dim}_mean" | |
| key_std = f"{dim}_std" | |
| if key_mean in metrics: | |
| print(f" {dim}: {metrics[key_mean]:.2f} +/- {metrics[key_std]:.2f}") | |
| print(f" Overall: {metrics.get('overall_mean', 0):.2f} +/- {metrics.get('overall_std', 0):.2f}") | |
| print(f" Parsed: {metrics.get('n_parsed', 0)}/{metrics.get('n_total', 0)}") | |
| print(f"\n=== All {len(runs)} runs judged ===") | |
| if __name__ == "__main__": | |
| main() | |