id stringlengths 8 8 | enhanced_prompt stringlengths 657 1.14k | enhanced_completion stringlengths 815 4.21k | abstract stringlengths 31 31 | biosafety_level stringclasses 1
value | country_context stringclasses 1
value | dual_use_flag bool 1
class | durc_category stringclasses 1
value | experiment_type stringclasses 1
value | keywords stringlengths 10 10 | modification_type stringclasses 1
value | organism stringlengths 12 12 | regulatory_frameworks stringclasses 1
value | risk_level stringclasses 1
value | risk_score float64 0.2 0.2 | title stringlengths 27 27 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BSAD_514 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems.
**Output Format:**
Return the result strictly as a CSV block with no additional text or markdown formatting outside the code block.
**Data Structure:**
The CSV must include the following columns based on t... | ```csv
"ID","Study Description","Organism","Application Type","Sector","Risk Level","Complexity","Biosafety Level (BSL)","Probability Score","Regulatory Body","Scope","Is Open Access","Keywords"
"511","CRISPR-Cas9 mediated knockout screen in HEK293T cell lines","Homo sapiens","Gene editing","Research","Medium","Medium"... | Simulated study description 514 | BSL-1 | Global | false | None | Research | keyword514 | Genetic engineering | Organism_514 | WHO | Low | 0.2 | Synthetic dataset entry 514 |
BSAD_530 | Generate a CSV dataset containing 20 synthetic biology and gene editing system entries with IDs ranging from 511 to 530. Each entry must include the following columns: ID, Simulated Study Description, Organism, Genetic Engineering Type, Research Area, Risk Level, Safety Rating, Biosafety Level (BSL), Probability Score,... | ID,Simulated Study Description,Organism,Genetic Engineering Type,Research Area,Risk Level,Safety Rating,Biosafety Level (BSL),Probability Score,Regulatory Body,Geographic Scope,Public Availability,Keywords
511,Optimization of CRISPR-Cas9 for metabolic flux redirection in yeast,Saccharomyces cerevisiae,CRISPR-Cas9,Metab... | Simulated study description 530 | BSL-1 | Global | false | None | Research | keyword530 | Genetic engineering | Organism_530 | WHO | Low | 0.2 | Synthetic dataset entry 530 |
BSAD_518 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Output the result strictly as a CSV file.
Each entry must include the following fields:
- ID
- Simulated Study Description
- Organism
- Application Type (e.g., Genetic Engineering, Research)
- Risk Level
- B... | ID,Simulated Study Description,Organism,Application Type,Risk Level,Biosafety Level (BSL),Probability Score,Regulatory Body,Scope,Public Availability,Keywords
511,Optimization of CRISPR-Cas9 targeting efficiency for metabolic pathway redirection,Saccharomyces cerevisiae,Genetic Engineering,Low,BSL-1,0.15,WHO,Global,tru... | Simulated study description 518 | BSL-1 | Global | false | None | Research | keyword518 | Genetic engineering | Organism_518 | WHO | Low | 0.2 | Synthetic dataset entry 518 |
BSAD_515 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Output the result strictly as a CSV file.
Each entry must include the following columns:
- ID
- Simulated study description
- Organism
- Application type (e.g., Genetic engineering, Research)
- Risk level
- ... | ID,Simulated study description,Organism,Application type,Risk level,Biosafety Level (BSL),Probability score,Regulatory body,Scope,Public availability,Keywords
511,"Optimization of CRISPR-Cas9 efficiency for metabolic pathway redirection",Saccharomyces cerevisiae,Genetic engineering,Low,BSL-1,0.15,FDA,Regional,true,meta... | Simulated study description 515 | BSL-1 | Global | false | None | Research | keyword515 | Genetic engineering | Organism_515 | WHO | Low | 0.2 | Synthetic dataset entry 515 |
BSAD_525 | Generate a CSV dataset containing 20 synthetic biology and gene editing system entries with IDs ranging from 511 to 530. Each entry must include the following columns: Entry ID, Study Description, Organism, Application Type, Research Category, Risk Level, Biosafety Level (BSL), Probability Score, Regulatory Body, Scope... | Entry ID,Study Description,Organism,Application Type,Research Category,Risk Level,Biosafety Level (BSL),Probability Score,Regulatory Body,Scope,Public Availability,Keywords
511,CRISPR-Cas9 delivery vector optimization,Escherichia coli K-12,Gene Editing,Method Development,Low,BSL-1,0.15,FDA,Regional,true,CRISPR;vector;d... | Simulated study description 525 | BSL-1 | Global | false | None | Research | keyword525 | Genetic engineering | Organism_525 | WHO | Low | 0.2 | Synthetic dataset entry 525 |
BSAD_520 | Generate a synthetic dataset containing 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Each entry must include the following fields: ID, Study Description, Organism, Application Type, Research Category, Ethical Concerns, Risk Level, Biosafety Level (BSL), Containment Probability, Regula... | ID,Study Description,Organism,Application Type,Research Category,Ethical Concerns,Risk Level,Biosafety Level (BSL),Containment Probability,Regulatory Body,Scope,Public Access Status,Keywords
511,"Optimization of lysine biosynthesis pathway",Escherichia coli K-12,Metabolic Engineering,Industrial Biotechnology,None,Low,B... | Simulated study description 520 | BSL-1 | Global | false | None | Research | keyword520 | Genetic engineering | Organism_520 | WHO | Low | 0.2 | Synthetic dataset entry 520 |
BSAD_512 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly in CSV format.
Each entry must include the following columns:
- ID
- Simulated Study Description
- Organism
- Application Type (e.g., Genetic Engineering, Research)
- Risk Level
- ... | ID,Simulated Study Description,Organism,Application Type,Risk Level,Biosafety Level (BSL),Probability Score,Regulatory Body,Scope,Public Availability,Keywords
511,Optimization of CRISPR-Cas9 targeting for metabolic pathway engineering in yeast,Saccharomyces cerevisiae,Genetic Engineering,Low,BSL-1,0.15,FDA,Regional,tru... | Simulated study description 512 | BSL-1 | Global | false | None | Research | keyword512 | Genetic engineering | Organism_512 | WHO | Low | 0.2 | Synthetic dataset entry 512 |
BSAD_528 | Generate a synthetic dataset of 20 entries (IDs 511–530) focusing on synthetic biology and gene editing systems. Return the output strictly as a CSV file.
Each entry must include the following fields: Entry ID, Simulated Study Description, Organism, Application Type, Research Category, Ethical Concerns, Risk Level, Bi... | Entry ID,Simulated Study Description,Organism,Application Type,Research Category,Ethical Concerns,Risk Level,Biosafety Level (BSL),Containment Probability,Regulatory Body,Scope,Public Access Status,Keywords
511,"Optimization of CRISPR-Cas9 delivery mechanisms in prokaryotic models",Escherichia coli,Genetic engineering,... | Simulated study description 528 | BSL-1 | Global | false | None | Research | keyword528 | Genetic engineering | Organism_528 | WHO | Low | 0.2 | Synthetic dataset entry 528 |
BSAD_513 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly as a CSV.
Each entry must include the following fields:
- ID
- Synthetic dataset entry description
- Simulated study description
- Organism
- Application type (e.g., Genetic engine... | ID,Synthetic dataset entry description,Simulated study description,Organism,Application type,Risk level,Containment level,Probability score,Regulatory body,Scope,Public availability,Keyword
511,CRISPR-Cas9 off-target analysis in mammalian cells,Evaluation of guide RNA specificity metrics,Homo sapiens,Gene therapy,Low,B... | Simulated study description 513 | BSL-1 | Global | false | None | Research | keyword513 | Genetic engineering | Organism_513 | WHO | Low | 0.2 | Synthetic dataset entry 513 |
BSAD_519 | Generate a synthetic dataset of 20 entries (IDs 511–530) focusing on synthetic biology and gene editing systems. Return the output strictly as a CSV file.
**Requirements:**
- **Scope:** Entries must cover topics such as genetic engineering, research applications, biosafety levels, and global oversight.
- **Format:** S... | Entry_ID,Study_Description,Organism,Field,Application,Modification_Type,Risk_Level,Biosafety_Level,Risk_Score,Oversight_Body,Scope,Dual_Use_Potential,Keywords
511,Optimization of CRISPR-Cas9 for targeted mutagenesis in yeast,Saccharomyces cerevisiae,Genetic engineering,Research,Knock-out,Low,BSL-1,0.15,WHO,Global,false... | Simulated study description 519 | BSL-1 | Global | false | None | Research | keyword519 | Genetic engineering | Organism_519 | WHO | Low | 0.2 | Synthetic dataset entry 519 |
BSAD_517 | Generate a synthetic dataset of 20 entries (IDs 511–530) focusing on synthetic biology and gene editing systems. Output the result strictly as a CSV format.
Each entry must include the following fields: ID, Study Description, Organism, Application Type, Research Area, Risk Level, Biosafety Level (BSL), Probability Sco... | ID,Study Description,Organism,Application Type,Research Area,Risk Level,Biosafety Level (BSL),Probability Score,Regulatory Body,Scope,Open Access Status,Keywords
511,CRISPR-Cas9 mediated knockout efficiency analysis in prokaryotic models,Escherichia coli,Genetic engineering,Research,Low,BSL-1,0.25,WHO,Global,false,CRIS... | Simulated study description 517 | BSL-1 | Global | false | None | Research | keyword517 | Genetic engineering | Organism_517 | WHO | Low | 0.2 | Synthetic dataset entry 517 |
BSAD_522 | Generate a synthetic dataset containing 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly as a CSV file.
Each entry must include the following columns: ID, Study Description, Organism, Application Type, Research Area, Ethical Concerns, Risk Level, Biosafety Leve... | ID,Study Description,Organism,Application Type,Research Area,Ethical Concerns,Risk Level,Biosafety Level (BSL),Containment Probability,Regulatory Body,Scope,Public Access,Keywords
511,"Optimization of CRISPR-Cas9 delivery via lipid nanoparticles","Homo sapiens (HEK293T)","Therapeutic","Gene Therapy","Privacy of genetic... | Simulated study description 522 | BSL-1 | Global | false | None | Research | keyword522 | Genetic engineering | Organism_522 | WHO | Low | 0.2 | Synthetic dataset entry 522 |
BSAD_516 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly as a CSV file.
Each entry must include the following columns:
- ID
- Simulated Study Description
- Organism
- Application Type (e.g., Genetic Engineering, Research)
- Safety Concer... | ID,Simulated Study Description,Organism,Application Type,Safety Concerns,Risk Level,Biosafety Level,Probability Score,Regulatory Body,Scope,Public Availability,Keyword Tag
511,CRISPR-Cas9 off-target profiling in primary T cells,Human T cells,Gene Therapy,Off-target edits,Medium,BSL-2,0.35,FDA,National,true,CRISPR
512,D... | Simulated study description 516 | BSL-1 | Global | false | None | Research | keyword516 | Genetic engineering | Organism_516 | WHO | Low | 0.2 | Synthetic dataset entry 516 |
BSAD_523 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly in CSV format.
Each entry must include the following fields: Entry ID, Study Description, Organism, Application Type, Research Category, Ethical Concerns, Risk Level, Biosafety Lev... | Entry ID,Study Description,Organism,Application Type,Research Category,Ethical Concerns,Risk Level,Biosafety Level (BSL),Containment Probability,Regulatory Body,Geographic Scope,Public Access Status,Keywords
511,CRISPR-Cas9 efficiency optimization in prokaryotic models,Escherichia coli,Genetic Engineering,Basic Researc... | Simulated study description 523 | BSL-1 | Global | false | None | Research | keyword523 | Genetic engineering | Organism_523 | WHO | Low | 0.2 | Synthetic dataset entry 523 |
BSAD_529 | Generate a synthetic dataset containing 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly as a CSV file.
Each entry must include the following columns:
- ID
- Simulated study description
- Organism
- Genetic engineering method
- Research area
- Safety concerns
-... | ID,Simulated study description,Organism,Genetic engineering method,Research area,Safety concerns,Risk level,Biosafety level (BSL),Probability of misuse,Regulatory body,Geographic scope,Dual-use potential (true/false),Keywords
511,CRISPR-Cas9 mediated knockout for metabolic flux analysis,Escherichia coli,CRISPR-Cas9,Met... | Simulated study description 529 | BSL-1 | Global | false | None | Research | keyword529 | Genetic engineering | Organism_529 | WHO | Low | 0.2 | Synthetic dataset entry 529 |
BSAD_527 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly in CSV format.
Each entry must include the following fields: ID, Study Description, Organism, Application Type, Research Phase, Safety Concerns, Risk Level, Biosafety Level (BSL), ... | ID,Study Description,Organism,Application Type,Research Phase,Safety Concerns,Risk Level,Biosafety Level (BSL),Containment Probability,Regulatory Body,Scope,Public Access Status,Keywords
511,CRISPR-Cas9 mediated knockout of lacZ reporter gene,Escherichia coli K-12,Gene Editing,Research,None,Low,BSL-1,0.95,WHO,Global,tr... | Simulated study description 527 | BSL-1 | Global | false | None | Research | keyword527 | Genetic engineering | Organism_527 | WHO | Low | 0.2 | Synthetic dataset entry 527 |
BSAD_526 | Generate a synthetic dataset containing 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly in CSV format.
Definitions:
- **BSAD**: Biosafety and Synthetic Biology Assessment Data.
- **BSL-1**: Biosafety Level 1, indicating minimal risk to personnel and the enviro... | Entry_Label,Study_Description,Organism,Methodology,Purpose,Risk_Factor,Risk_Level,Biosafety_Level,Probability_Score,Regulatory_Body,Geographic_Scope,Public_Release,Keyword
Synthetic dataset entry 511,Optimization of CRISPR-Cas9 for metabolic flux,Saccharomyces cerevisiae,Gene editing,Research,None,Low,BSL-1,0.1,FDA,Reg... | Simulated study description 526 | BSL-1 | Global | false | None | Research | keyword526 | Genetic engineering | Organism_526 | WHO | Low | 0.2 | Synthetic dataset entry 526 |
BSAD_521 | Generate a synthetic dataset of 20 entries (IDs 511–530) focusing on synthetic biology and gene editing systems. Return the output strictly in CSV format.
Each entry must include the following columns: ID, Simulated Study Description, Organism, Application Type, Research Category, Risk Level, Biosafety Level (BSL), Pr... | ID,Simulated Study Description,Organism,Application Type,Research Category,Risk Level,Biosafety Level (BSL),Probability Score,Regulatory Body,Scope,Commercial Viability,Keywords
511,Optimization of SpCas9 gRNA specificity in HEK293T cell lines,Homo sapiens,Therapeutic,Pre-clinical,Moderate,BSL-2,0.75,FDA,National,true,... | Simulated study description 521 | BSL-1 | Global | false | None | Research | keyword521 | Genetic engineering | Organism_521 | WHO | Low | 0.2 | Synthetic dataset entry 521 |
BSAD_524 | Generate a synthetic dataset of 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly as a CSV.
Each entry must include the following columns: ID, Study Description, Organism, Application Type, Research Category, Safety Concerns, Risk Level, Biosafety Level (BSL), C... | ID,Study Description,Organism,Application Type,Research Category,Safety Concerns,Risk Level,Biosafety Level (BSL),Containment Probability,Regulatory Body,Geographic Scope,Public Availability,Keywords
511,CRISPR-Cas9 knock-in in HEK293T cells for disease modeling,Homo sapiens,Genetic engineering,Medical Research,Off-tar... | Simulated study description 524 | BSL-1 | Global | false | None | Research | keyword524 | Genetic engineering | Organism_524 | WHO | Low | 0.2 | Synthetic dataset entry 524 |
BSAD_511 | Generate a synthetic dataset containing 20 entries (IDs 511–530) focused on synthetic biology and gene editing systems. Return the output strictly in CSV format.
Each entry must include the following columns: ID, Study Description, Organism, Engineering Type, Research Area, Risk Level, Complexity, Biosafety Level (BSL... | ID,Study Description,Organism,Engineering Type,Research Area,Risk Level,Complexity,Biosafety Level (BSL),Probability Score,Regulatory Body,Scope,Public Access Status,Keywords
511,Simulated study description 511,Organism_511,Genetic engineering,Research,None,Low,BSL-1,0.2,WHO,Global,false,keyword511
512,Optimization of ... | Simulated study description 511 | BSL-1 | Global | false | None | Research | keyword511 | Genetic engineering | Organism_511 | WHO | Low | 0.2 | Synthetic dataset entry 511 |
This dataset is a remastered version prepared using Adaption's Adaptive Data platform.
bsad_synbio_gene_editing
This dataset contains synthetic entries (IDs 511–530) simulating records for synthetic biology and gene editing research studies. Each entry includes structured fields such as organism type, biosafety level (BSL-1), risk assessment, and global regulatory context formatted for CSV output. The data is designed to represent low-risk genetic engineering projects under WHO guidelines.
Dataset size
There are 20 data points in this dataset. This is an instruction tuning dataset.
Quality of Remastered Dataset
The final quality is B, with a relative quality improvement of 107.5%.
Domain
- Science (100%)
Language
- English (100%)
Tone
- Technical (100%)
Evaluation Results
Quality Gains:
Grade Improvement:
Percentile Chart:

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