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> How do I remove all the /cygdrive/c, cygdrive/d mounts? I have been searching on google, looked at the FAQ, searched the archives but i can't find any way to do this.
/cygdrive/. What are you hoping to accomplish by removing them, anyway? | c4 |
When you have acne, you may try just about anything to help clear it up. While there are some alternative treatments, such as tea tree oil, that may help you manage the outbreaks, drinking vinegar is not one of them. Talk to your doctor about how to manage your acne.
The belief is that drinking vinegar, specifically apple cider vinegar, helps clear up your acne by helping remove toxins and impurities from your blood. However, like any detox claim, there's no evidence to support it other than anecdotal, according to KidsHealth.org. Plus, there are concerns that drinking vinegar daily may erode the enamel on your teeth.
While drinking vinegar may not help improve your skin, there are changes that you can make to your diet that may help. Eating a diet filled with low-glycemic carbs, such as whole grains, beans, fruits and vegetables, may be the way to go, according to the American Academy of Dermatology Association. Drinking too much milk may also exacerbate the skin condition, says AADA. However, more research is necessary, so don't cut milk out of your diet without first talking to your doctor. | c4 |
Life for teenagers can be challenging enough, but with exam time upon us stress levels are rising. This invariably takes it's toll on family life which isn't fun for anyone! We thought we'd share our top tips for overcoming this stress and helping to bring a little calm back into your homes. | c4 |
In this short video Maz is demonstrating how to create Clips (from 0:08-0:39) and share Playlists (0:40-1:22).
In order to create playlists, you need to have at least couple of tags.
Click ‘Create Playlist’ at the bottom left corner of the video.
Download button (orange button with the white cloud and an arrow) which is used to download created playlist to your device.
Copy button which is used to copy URL. E.g. you can paste it in our Activity feed to share it with your team. | c4 |
This makes the perfect pork chop in a pan or on the grill. Simply sprinkle as much or as little as you want on your chop and don't forget to split the fat with a knife on the side of your chop to prevent it from curling one way or the other! Small Particle Size. | c4 |
Does chopping onions turn on the water works? For me it certainly does. Next time, try breathing through your nose only (that means no talking) and kiss those tears goodbye! | c4 |
This unique dish is perfect for a party of many - or just one! Make sure to make the meatballs a few hours ahead of time for ultimate flavor. And, if you don't finish the entire plate in one sitting? Freeze those meatballs and save 'em for later!
1.Place a coarse grater in the middle of a large bowl. Cut off a slice from the root of the tomato and discard; grate the rest into the bowl. Next, grate the onion straight into the bowl with the tomato. Add the salt, pepper, oregano, mint, breadcrumbs, Parmesan cheese and milk and mix well. Last, add the ground beef and mix thoroughly to incorporate. If the mixture is too dry, add some more Parmesan cheese. If it is too loose, add some more milk. Drizzle the olive oil over the surface, cover well and refrigerate for an hour (or even overnight).
2.Preheat the oven to 375°F.
3.To form the mini meatballs, use a tablespoon to measure out a little bit of the mixture and roll it between your palms into a small ball. It should be slightly smaller than a golf ball. Place on a baking sheet, lined with aluminum foil. Continue with the remaining mixture until all the meatballs are shaped, placing them closely to each other in the sheet.
4.Bake for about 25 minutes, depending on their size, until lightly brown (you do not need to turn them while baking). Remove from the oven and transfer to a tray.
5.At this point, you can serve them as is, or, add them to you favorite tomato sauce and simmer for 15 minutes. Either way, let them come to room temperature.
6.Cut the cucumbers into disks, place one small meatball on top and serve with decorative toothpicks. Alternatively, pile them all on one side of a tray and place the cucumbers on the other side, then allow your guests to help themselves!
Note: - The meatballs may be made at least three hours ahead of time and stored, covered, until ready to use. The recipe makes a whole tray’s worth of meatballs. Make the whole recipe and freeze the unused meatballs, after they are cooked and cooled down. | c4 |
Will be doing a review on some of these goodies soon!
Bare with me while i give them a try!
Has anyone tried any of these products before? Let me know what you think! | c4 |
Even if you are not traveling to an English-speaking country, as a tourist, you will need to communicate with people at the airport, and at tourist attractions. Watch this lesson, take the quiz, and have a safe trip!
Test yourself on travel English with this fun quiz. | c4 |
,, a very wise man ….
Love it! And right on!
I always wondered who said that first. | c4 |
Hear expert testimony from leading evolutionary scientists at some of the world’s top universities. Watch as they present their most compelling evidence for Darwinian evolution. Their answers will amaze you! If you believe in evolution, prepare to have your faith shaken. | c4 |
The blood-brain barrier (BBB) is a cellular and metabolic barrier located at the capillaries in the brain that alters permeability, restricting the passage of some chemical substances and microscopic objects from the bloodstream into the neural tissue, while allowing other substances to pass into the brain. For example, the blood-brain barrier restricts the passage of bacteria, red-blood cells, and certain toxins and water-soluble molecules into the brain while allowing the passage of oxygen, glucose, amino acids, white-blood cells, anesthetics, and alcohol.
Found in all vertebrates, as well as in certain invertebrates (such as the squid and octopus), the blood-brain barrier functions to protect neural tissue from harmful chemicals and bacterial infections. It also works to control volume in the vertebrate brain, with its hard brain case, by maintaining constant levels of ions and peptides and limiting the movement of water and salts.
There are several components of the blood-brain barrier in vertebrates. On the main features is the tight junctions involving cells in the brain blood capillaries that are tightly sealed together. There also is lipid/protein bilayer that protects against water-soluble substances, an enzymatic barrier that removes unwanted peptides and other small molecules, and efflux pumps that transport certain molecules back into the blood that have passed into the brain. The mechanism also includes carriers that transport necessary substances from the blood to the brain and removes waste products.
The blood-brain barrier is an intricately coordinated mechanism for protecting the brain. It is essential for the functioning of the complex brain of vertebrates. The breakdown of the blood-brain barrier is implicated in several diseases, including meningitis, epilepsy, and multiple sclerosis. However, even when functioning properly, the blood-brain barrier cannot protect against the entry of some harmful substances, such as viruses, which have developed mechanisms to bypass the barrier. The blood-brain barrier also restricts the entry of antibodies that help to fight bacterial infections that do occur and makes it difficult for the delivery of water-soluble drugs that have been developed to treat diverse conditions. However, an understanding of the mechanism of the blood-brain barrier has allowed researchers to develop means to deliver such drugs.
The blood-brain barrier helps to separate the brain from the bloodstream, allowing the select filtering of molecules and objects that are allowed to enter the brain. Certain substances that are harmful are prevented from entering the brain from the bloodstream, such as toxins and bacteria. Other substances that are necessary for the metabolic activities of the brain, such as glucose for energy, oxygen for respiration, and amino acids for building proteins, are allowed to pass through this barrier. In addition, the barrier helps to maintain the volume of the brain fluid, since the brain is located in a rigid skull. This it does by limiting the movement of salts and water from the blood into the extracellular fluid and the BBB secretes brain extracellular fluid at a controlled rate to help maintain brain volume (Segal 2001).
The blood-brain barrier acts very effectively to protect the brain from many common bacterial infections. Thus, infections of the brain are very rare. However, since antibodies are too large to cross the blood-brain barrier, infections of the brain that do occur are often very serious and difficult to treat. Viruses easily bypass the blood-brain barrier, however, attaching themselves to circulating immune cells. The HIV virus uses the brain as a sanctuary, hiding behind the blood-brain barrier from the defense mechanisms of the body (Segal 2001).
Several areas of the brain are not "behind" the BBB. One example is the pineal gland, which secretes the hormone melatonin "directly into the systemic circulation" (Pritchard and Alloway 1999).
Segal (2001) notes that the blood-brain barrier is found in all vertebrates, as well as in squids and octopuses, with an analogous structure in insects. In humans, it is formed by the third month of gestation.
The blood-brain barrier is located at the level of the brain blood capillaries. There are several components of the barrier.
Tight junctions. A key component of the blood-brain barrier is the tight junctions between endothelial cells in central nervous system capillary vessels that restricts the passage of solutes. At the interface between blood and brain, endothelial cells and associated astrocytes (type of glia) are stitched together by structures called "tight junctions." The tight junction is composed of smaller subunits, frequently dimers, that are transmembrane proteins such as occludin, claudins, junctional adhesion molecule (JAM), ESAM, and others. Each of these transmembrane proteins is anchored into the endothelial cells by another protein complex that includes zo-1 and associated proteins. The sealing together by tight junctions of the cells making up the walls of the vessels prevents water-soluble substances from freely passing between the cells and entering the fluid environment of the brain cells (Segal 2001).
The blood-brain barrier restricts passage of substances from the bloodstream by high density cells much more than endothelial cells in capillaries elsewhere in the body. Astrocyte cell projections called astrocytic feet (also known as "glia limitans") surround the endothelial cells of the BBB, providing biochemical support to those cells. The BBB is distinct from the similar blood-cerebrospinal fluid barrier, a function of the choroidal cells of the choroid plexus, and from the Blood-retinal barrier, which can be considered a part of the whole (Hamilton et al. 2007).
Lipid barrier. The tight junctions of the cells making up the capillary walls and the densely packed astrocyte foot processes that surround the endothelial cells of the tight junctions act as a partial, active, barrier. Water-soluble substances can only cross through the BBB by passing directly through the walls of the brain capillaries. But the cell membranes they have to pass through are made up of a lipid/protein bilayer that acts as a barrier against water-soluble molecules and serves as a major component of the BBB. However, fat-soluble molecules, such as anesthetics and alcohol, as well as oxygen and carbon dioxide, can pass straight through the lipids in the capillary walls and enter the brain area (Segal 2001).
Enzymatic barrier. In addition to the above-mentioned passive components of the blood-brain barrier, there also are enzymes on the lining of the capillaries that actively destroy undesirable peptides and other small molecules in the blood that is flowing through the brain, thus removing them from the blood (Segal 2001).
Efflux pumps. There are three classes of "efflux pumps" in the capillary wall that bind to three classes of fat-soluble molecules that could be toxic and that have diffused through the capillary walls into the brain. These efflux pumps then transport these molecules back into the blood (Segal 2001).
These are components of the barrier between the blood and the brain. However, there also are means for water-soluble compounds to cross the blood-brain barrier, such as glucose and amino acids. These are transported into the brain by special carriers on both sides of the cells forming the capillary walls. These also act to move waste products and other undesirable molecules from the brain to the blood (Segal 2001).
Paul Ehrlich was a bacteriologist studying staining, used for many studies to make fine structures visible. When he interjected some of these dyes (notably the aniline dyes that were then popular), the dye would stain all of the organs of an animal except the brain. At the time, Ehrlich attributed this to the brain simply not picking up as much of the dye.
However, in a later experiment in 1913, Edwin Goldmann (one of Ehrlich's students) injected the dye into the spinal fluid of the brain directly. He found that in this case the brain would become dyed, but the rest of the body would not. This clearly demonstrated the existence of some sort of compartmentalization between the two. At the time, it was thought that the blood vessels themselves were responsible for the barrier, as no obvious membrane could be found.
The concept of the blood-brain barrier (then termed hematoencephalic barrier) was proposed by Lina Stern in 1921 (Vein 2006). It was not until the introduction of the scanning electron microscope to the medical research fields in the 1960s that the actual membrane could be demonstrated.
It was once believed that astrocytes rather than endothelial cells were the primary physical component of the blood-brain barrier because of the densely packed astrocyte foot processes that surround the endothelial cells of the BBB.
Overcoming the difficulty of delivering therapeutic agents to specific regions of the brain presents a major challenge to treatment of most brain disorders. In its neuroprotective role, the blood-brain barrier functions to hinder the delivery of many potentially important diagnostic and therapeutic agents to the brain. Therapeutic molecules and genes that might otherwise be effective in diagnosis and therapy do not cross the BBB in adequate amounts.
Mechanisms for drug targeting in the brain involve going either "through" or "behind" the BBB. Modalities for drug delivery through the BBB entail its disruption by osmotic means, biochemically by the use of vasoactive substances such as bradykinin, or even by localized exposure to high intensity focused ultrasound (HIFU). Other strategies to go through the BBB may entail the use of endogenous transport systems, including carrier-mediated transporters such as glucose and amino acid carriers; receptor-mediated transcytosis for insulin or transferrin; and blocking of active efflux transporters such as p-glycoprotein. Strategies for drug delivery behind the BBB include intracerebral implantation and convection-enhanced distribution.
Nanotechnology may also help in the transfer of drugs across the BBB (Silva 2008). Recently, researchers have been trying to build liposomes loaded with nanoparticles to gain access through the BBB. More research is needed to determine which strategies will be most effective and how they can be improved for patients with brain tumors. The potential for using BBB opening to target specific agents to brain tumors has just begun to be explored.
Delivering drugs across the blood brain barrier is one of the most promising applications of nanotechnology in clinical neuroscience. Nanoparticles could potentially carry out multiple tasks in a predefined sequence, which is very important in the delivery of drugs across the blood brain barrier.
A significant amount of research in this area has been spent exploring methods of nanoparticle mediated delivery of antineoplastic drugs to tumors in the central nervous system. For example, radiolabeled polyethylene glycol coated hexadecylcyanoacrylate nanospheres targeted and accumulated in a rat gliosarcoma (Brigger et al. 2002). However, this method is not yet ready for clinical trials due to the accumulation of the nanospheres in surrounding healthy tissue.
It should be noted that vascular endothelial cells and associated pericytes are often abnormal in tumors and that the blood-brain barrier may not always be intact in brain tumors. Also, the basement membrane is sometimes incomplete. Other factors, such as astrocytes, may contribute to the resistance of brain tumors to therapy (Hashizume et al. 2000; Schenider et al. 2004).
Errors in the development of the BBB in humans can lead to such defects as spina bifida. When trauma or infection makes the barrier leaky, water and salts crossing the barrier can result in swelling of the brain (cerebral oedema), leading to raised intercranial pressure, which can become fatal (Segal 2001).
There are currently active investigations into treatments for a compromised blood-brain barrier. It is believed that oxidative stress plays an important role into the breakdown of the barrier; anti-oxidants such as lipoic acid may be able to stabilize a weakening blood-brain barrier (Schreibelt et al. 2006).
Several other major conditions tied to a breakdown in the BBB are detailed below.
Meningitis is inflammation of the membranes that surround the brain and spinal cord. (These membranes are also known as meninges.) Meningitis is most commonly caused by infections with various pathogens, examples of which are Streptococcus pneumoniae and Haemophilus influenzae. When the meninges are inflamed, the blood-brain barrier may be disrupted. This disruption may increase the penetration of various substances (including antibiotics) into the brain. Antibiotics used to treat meningitis may aggravate the inflammatory response of the central nervous system by releasing neurotoxins from the cell walls of bacteria like lipopolysaccharide (LPS) (Beam and Allen 1977). Treatment with third generation or fourth generation cephalosporin is usually preferred.
Epilepsy is a common neurological disease characterized by frequent and often untreatable seizures. Several clinical and experimental data have implicated failure of blood-brain barrier function in triggering chronic or acute seizures (Oby and Janigro 2006; Marchi et al. 2007; Seiffert et al. 2004; Urva et al. 2007; van Vliet et al. 2007). These findings have shown that acute seizures are a predictable consequence of disruption of the BBB by either artificial or inflammatory mechanisms. In addition, expression of drug resistance molecules and transporters at the BBB are a significant mechanism of resistance to commonly used anti-epileptic drugs (Awasthi et al. 2005; Loscher and Potschka 2005).
Multiple sclerosis (MS) is considered an auto-immune disorder in which the immune system attacks the myelin protecting the nerves in the central nervous system. Normally, a person's nervous system would be inaccessible for the white blood cells due to the blood-brain barrier. However, it has been shown using Magnetic Resonance Imaging that, when a person is undergoing an MS "attack," the blood-brain barrier has broken down in a section of the brain or spinal cord, allowing white blood cells called T lymphocytes to cross over and destroy the myelin. It has been suggested that, rather than being a disease of the immune system, MS is a disease of the blood-brain barrier. However, current scientific evidence is inconclusive.
Neuromyelitis optica, also known as Devic's disease, is similar to and often confused with multiple sclerosis. Among other differences from MS, the target of the autoimmune response has been identified. Patients with neuromyelitis optica have high levels of antibodies against a protein called aquaporin 4 (a component of the astrocytic foot processes in the blood-brain barrier) (Lennon et al. 2005).
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of a latent papovavirus (the JC polyomavirus) infection, that can cross the BBB. It affects immune-compromised patients and is usually seen with patients having AIDS.
De Vivo disease (also known as GLUT1 deficiency syndrome) is a rare condition caused by inadequate transport of glucose across the barrier, resulting in mental retardation and other neurological problems. Genetic defects in glucose transporter type 1 (GLUT1) appears to be the main cause of De Vivo disease (Pascual et al. 2004; Klepper and Voit 2002).
New evidence indicates that disruption of the blood brain barrier in AD patients allows blood plasma containing amyloid beta (Aβ) to enter the brain where the Aβ adheres preferentially to the surface of astrocytes. These findings have led to the hypotheses that: (1) breakdown of the blood-brain barrier allows access of neuron-binding autoantibodies and soluble exogenous Aβ42 to brain neurons; and (2) binding of these autoantibodies to neurons triggers and/or facilitates the internalization and accumulation of cell surface-bound Aβ42 in vulnerable neurons through their natural tendency to clear surface-bound autoantibodies via endocytosis. Eventually the astrocyte is overwhelmed, dies, ruptures, and disintegrates, leaving behind the insoluble Aβ42 plaque. Thus, in some patients, Alzheimer’s disease may be caused (or more likely, aggravated) by a breakdown in the blood brain barrier (Nagele 2006).
The herpes virus produces the amyloid beta (Aβ) and has been found to be the pathogen responsible for being a major cause of the disease (UM 2008).
It is believed that latent HIV can cross the blood-brain barrier inside circulating monocytes in the bloodstream ("Trojan horse theory") within the first 14 days of infection. Once inside, these monocytes become activated and are transformed into macrophages. Activated macrophages release virions into the brain tissue proximate to brain microvessels. These viral particles likely attract the attention of sentinel brain microglia and perivascular macrophages initiating an inflammatory cascade that may cause a series of intracellular signaling in brain microvascular endothelial cells and damage the functional and structural integrity of the BBB. This inflammation is HIV encephalitis (HIVE). Instances of HIVE probably occur throughout the course of AIDS and are a precursor for HIV-associated dementia (HAD). The premier model for studying HIV and HIVE is the simian model.
Awasthi, S. et al. 2005. RLIP76, a non-ABC transporter, and drug resistance in epilepsy. BMC. Neurosci. 6: 61.
Beam, T. R., and J. C. Allen. 1977. Blood, brain, and cerebrospinal fluid concentrations of several antibiotics in rabbits with intact and inflamed meninges. Antimicrobial agents and chemotherapy 12(6): 710–716. PMID 931369. Retrieved February 23, 2009.
Brigger, I., J. Morizet, G. Aubert, et al. 2002. Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting. J. Pharmacol. Exp. Ther. 303(3): 928–936. PMID 12438511. Retrieved February 23, 2009.
Hamilton, R. D., A. J. Foss, and L. Leach. 2007. Establishment of a human in vitro model of the outer blood-retinal barrier. Journal of Anatomy 211: 707. PMID 17922819. Retrieved February 23, 2009.
Hashizume, H., P. Baluk, S. Morikawa, J. W. McLean, G. Thurston, S. Roberge, R. K. Jain, and D. M. McDonald. 2000. Openings between defective endothelial cells explain tumor vessel leakiness. American Journal of Pathology 156(4): 1363–1380. PMID 10751361. Retrieved February 23, 2009.
Klepper, J., and T. Voit. 2002. Facilitated glucose transporter protein type 1 (GLUT1) deficiency syndrome: impaired glucose transport into brain: A review. European Journal of Pediatrics 161(6): 295–304. PMID 12029447. Retrieved February 23, 2009.
Lennon, V. A., T. J. Kryzer, S. J. Pittock, A. S. Verkman, and S. R. Hinson. 2005. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J. Exp. Med. 202(4): 473–477. PMID 16087714. Retrieved February 23, 2009.
Loscher, W., and H. Potschka. 2005. Drug resistance in brain diseases and the role of drug efflux transporters. Nat. Rev. Neurosci. 6: 591-602.
Marchi, N. et al. 2007. Seizure-promoting effect of blood-brain barrier disruption. Epilepsia 48(4): 732-742.
Nagele, R. G. 2006. Alzheimer's disease: New mechanisms for an old problem. University of Medicine and Dentistry of New Jersey Research 7(2). Retrieved February 23, 2009.
Oby, E., and D. Janigro. 2006. The Blood-brain barrier and epilepsy. Epilepsia 47(11): 1761-1774.
Pascual, J. M., D. Wang, B. Lecumberri, H. Yang, X. Mao, R. Yang, and D. C. De Vivo. 2004. GLUT1 deficiency and other glucose transporter diseases. European Journal of Endocrinology 150(5): 627–633. PMID 15132717. Retrieved February 23, 2009.
Pritchard, T. C., and K. D. Alloway. 1999. Medical Neuroscience. Hayes Barton Press. ISBN 1889325295.
Schneider, S. W., T. Ludwig, L. Tatenhorst, S. Braune, H. Oberleithner, V. Senner, and W. Paulus. 2004. Glioblastoma cells release factors that disrupt blood-brain barrier features. Acta Neuropathologica 107(3): 272–276. PMID 14730455. Retrieved February 23, 2009.
Schreibelt, G., R. J. Musters, A. Reijerkerk, et al. 2006. Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity. J. Immunol. 177(4): 2630–2637. PMID 16888025. Retrieved February 23, 2009.
Segal, M. 2001. Blood-brain barrier. In C. Blakemore, and S. Jennett. The Oxford Companion to the Body. New York: Oxford University Press. ISBN 019852403X.
Seiffert, E. et al. 2004. Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex. J. Neurosci. 24: 7829-7836.
Silva, G. A. 2008. Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS. BMC Neuroscience 9(Suppl. 3): S4. PMID 19091001. Retrieved February 23, 2009.
University of Manchester (UM). 2008. Cold sore virus linked to Alzheimer's. University of Manchester. Retrieved February 23, 2009.
Uva, L., L. Librizzi, N. Marchi, et al. 2007. Acute induction of epileptiform discharges by pilocarpine in the in vitro isolated guinea-pig brain requires enhancement of blood-brain barrier permeability. Neuroscience 151(1): 303-312. Retrieved February 23, 2009.
van Vliet, E. A. et al. 2007. Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy. Brain 130: 521-534.
Vein, A. A. 2006. Lina Stern: Science and fate. 11th Annual Meeting of the International Society for the History of the Neurosciences (ISHN). Retrieved February 23, 2009.
This page was last modified on 24 February 2009, at 01:49. | c4 |
The salt cell or electrode is the main component in the chlorinator. Coated in precious metals the cell electrolytically converts salt in the pool water to chlorine.
This process of electrolysis will eventually wear away the delicate coating on the salt cell, reducing its ability to produce chlorine.
Once the electrodes wear out, chlorine imbalances can occur and a new cell is needed. Over time, scale can also build up on these delicate components. Mineral content is present in all water and scale build up leads to less chlorine production.
Testing pool water salt levels and keeping the water in balance will prolong the life of salt cell. Buying a replacement salt cell is the big maintenance cost for the salt chlorinator. With so many different brands of salt chlorinator on the market, finding the right salt cell can be time consuming.
For easy cross reference, Epools’ website lists over 200 different brands of salt cell, each with a photo and dimensions. Made from high grade components, all replacements cells have quick release terminals for easy removal. Epools will have a replacement salt cell for all Chlorinator brands including Clearwater, Chloromatic and Saltmate. | c4 |
pastry (pas•tre) n. 1. Flour dough or paste made with shortening and used for the crust of pies, tarts, etc. 2. Broadly, all fancy baked goods, including cakes, sweet rolls, etc. | c4 |
It takes small steps to get where you're going.
Failure is your best friend.
Good habits are your next best friend.
-Page 117 of "Success for TEENS " by the editors of the SUCCESS Foundation. | c4 |
Did you know that every type ofinvestment has some risk? Investments that are expected to have higher returns also have higher risk. You need to be comfortable with the level of risk you’re taking. | c4 |
A diet rich in whole foods is healthy and delicious! Shop whole foods products like grains, fruit & veg, legumes and more in our whole foods online store.
Omega Seed Mix - Organic. | c4 |
Corns are calluses that form on the toes because of bones that push up against shoes and build up pressure on the skin. The surface layer of the skin thickens, irritating the tissues underneath.
Hard corns are usually located on the top of the toe or on the side of the small toe. Soft corns resemble open sores and develop between the toes as they rub against each other.
Improperly fitting shoes are a leading cause of corns. Toe deformities, such as hammertoe or claw toe, also can lead to corns. Self-care for corns includes soaking feet regularly and using a pumice stone or callus file to reduce the size of the corn. Special over-the-counter, non-medicated, donut-shaped foam pads can be worn to help relieve the pressure and discomfort. | c4 |
Organic gardening can be a very enjoyable hobby. It involves particular growing techniques, along with the gardener’s choice of equipment and seeds. This vast world has so many different kinds of seeds, equipment, and techniques that it can seem a bit confusing as to where you need to begin. These tips can help you make sense of the confusion.
While organic gardening can be a personal hobby for everyone, it does share the main goal of wanting to grow healthy and happy organic plants. As you have seen in these tips, there are various approaches, but they all share the goal of being a successful organic gardener. | c4 |
Coil-Rite air helper springs provide extra load support for coil springs in your 2007-2014 Volkswagen EOS. The complete adjustability of coil-rite air helper springs will level your vehicle, provide a smoother ride, more effective braking and handling, even under heavy loading and adverse road conditions. If you are looking to better the overall stability of your driving experience, air bag helper springs are the choice for you. | c4 |
Every venomous snake belongs to a particular snake family. To tell which one, just look for the clues. Is the snake's head shaped like a triangle? Does the snake have fixed fangs that do not move, or do its fangs spring forward? Don't get too close, but get ready to meet the families! | c4 |
SHELFIE | What Does SHELFIE Mean?
SHELFIE means "Shelf Selfie". A SHELFIE is a photo taken to show off what is on someone's shelf. Typically, the person taking the photograph is also in the picture. SHELFIES are usually taken to show off books, figures, or collectable memorabilia. Many believe the term was coined by author Rick Riordan.
SHELFIES probably came about as a result of the popularity of SELFIE. SHELFIE is a witticism based on SELFIE.
The image shows a man taking a picture with a bookshelf.
Person A: I color-coded my bookshelf. It's truly a work of art.
Person B: Let's see it then. Take a SHELFIE.
The term SHELFIE is an amalgam of the words "shelf" and "selfie." | c4 |
Armed and dangerous... Wanna Fence? Great gift for yourself or your favorite fencing female!
Raise a smile with this great gift for the wife of any keen golfer. It will suit her to a tee! | c4 |
According to the citation style you are using, you have different rules for which words are capitalized in an article title. This tool, Capitalize My Title, helps you to automatically capitalize a title or headline. It uses Chicago style, APA style, MLA style and AP style.
This entry was posted in Bibliographic Management and tagged Capitalization, References by fhilibrary. Bookmark the permalink. | c4 |
Mix all ingredients together. Pour in a large flat container . Refrigerate until set. Cut shapes with a knife or use scissors. | c4 |
@officialdjanomaly This snapshot is lovely!!
@gogo_winter1836 What song is this ???
@taglessproject This snapshot looks magnificent!!
@solupreneurgraphics Your page is excellent. i am a graphics designer. | c4 |
A hand is broken inside the watch face! What should I do?
Why won't my watch keep time?
Where can I find new wrist bands for my watch? | c4 |
To buy a swim wetsuit, or not to buy a wetsuit? Answers around the new FINA wetsuit rules!
To buy a swimming wetsuit, or not to buy a wetsuit? That is the question! Swim England Masters and Open Water Officer Sharon Lock answers your most popular questions around the new FINA wetsuit rules.
Some of you may be enthused and may even consider your first open water event. Others will be disappointed because they don’t want to be ‘made to wear a wetsuit’.
FINA conducted research into swimming in lower temperatures and have used this as guidance to devise the rules around when to wear a wetsuit and what defines a swimming wetsuit.
Water temperature of 20 °C and above: no wetsuit.
Water temperature between 18 and 19.9 °C: swimmer can choose to wear a wetsuit or not.
Water temperature between 16 and 17.9 °C: wetsuits are compulsory.
Water temperature below 15.9 °C: swimmers should not be competing.
The rules state a swim wetsuit is made of material providing thermal insulation, shall completely cover torso, back, shoulders and knees. They shall not extend past neck, wrists and ankles.
However, there are alternatives. You can hire one online or from a lot of suppliers but our best advice is to talk to other people and try lots of different suits until you find the one that fits you well. | c4 |
Craft room build. Complete post with pics to come!
Craft room table painting project with Annie Sloan Chalk Paint. Post to follow with more pics and details.
Grandma’s antique hutch painted with ASCP. Details to follow soon! | c4 |
I usually don't make it up in time to see the sunrise. However, since the sun isn't rising until around 8 am these days I was up in time to capture this. Isn't it beautiful?
sweet pictures! i like em! | c4 |
When eating McDonald's and my friend asks. Aren't you on a diet?
When eating McDonald’s and my friend asks. Aren’t you on a diet? No Damn! you feel guilty because the caught you cheating on your diet. | c4 |
Because in the Foreign Service, poop happens. By Francesca Kelly.
Heather Torrance on the single more frustrating aspect of being a Foreign Service spouse.
Jen Dinoia notes the many difficulties (and ironies) of researching a bid list with no access to the State Department Intranet.
Language training and the Foreign Service spouse. By Dave Pernal.
A very special Foreign Service take on the classic poem by Clement Moore. By Francesca Kelly. | c4 |
Enabled indicates whether the Windows® Customer Experience Improvement Program (CEIP) is enabled.
If CEIP is enabled, it collects and sends data to Microsoft® about Windows usage. Participation in this program is voluntary, and the results are recorded to implement improvements for future releases.
This setting has no effect on Server Core installations of Windows Server® 2008, Windows Server 2008 R2, and Windows Server 2012.
Specifies that Windows CEIP is chosen during OOBE. If the user decides to skip OOBE during installation, CEIP will be opted out. The user receives no further notifications.
Specifies that Windows CEIP collects and sends anonymous data to Microsoft to help improve Windows. | c4 |
2. Place 2 of the tortillas on a cookie sheet (do not grease).
3. Spread tortillas with pizza sauce. Top each with pepperoni, mushrooms, 1/2 cup of the cheese and then the other 2 tortillas.
4. Broil about 2 minutes, until tortillas are very lightly browned.
5. Flip quesadillas over and top with 1/2 cup cheese. Broil another 2 minutes, until cheese is melted. Top with parsley. | c4 |
The world is an ever changing place. If it's in the news, chances are Carrie fans are talking about it here!
Who is Gigi Gorgeous Dating?
Meghan Lindsey Poisonous Spider Bite leave HOLE IN FACE! | c4 |
How to get ready for a 5k run. From training plans and what to eat through to getting the best from your performance on the day.
How can I stay a motivated runner?
Can running help you lose belly fat? | c4 |
On average, Americans eat over a pound of tilapia each year.
Tilapia is the fourth most eaten fish in the United States, after tuna, salmon, and Alaskan pollock.
Tilapia is predicted to remain popular as food because of its mild flavor, ease of preparation, and affordability.
Because tilapia is primarily a farm-raised fish and is known for being easily genetically edited, it has been dubbed a "frankenfish."
China is the largest producer of tilapia, manufacturing over 50% of the world's supply.
Tilapia are ideal for farming because they reproduce quickly, eat pretty much anything, don't mind overcrowding, and can live in any type of water.
Tilapia has been farm-raised as far back as ancient Egyptian times, and it is set to become one of the most farmed seafood products in the 21st century.
The term "tilapia" refers to nearly a hundred species of fish. They come in a variety of colors, but the red and black species are the most popular as food.
Even though two companies, AquaBounty and Intrexon, jointly developed a gene-edited line of tilapia, they are exempt from genetically modified regulation because the engineered tilapia was not developed using gene editing techniques and does not contain any foreign DNA.
The word "tilapia" isn't the name of a single species of fish; it's a genus. There are about 100 different species of the fish. The word for the most common genus of Tilapia, cichlid, comes from the Latin derivative "thiape," which is the Tswana word for "fish."
As long as tilapia are raised in high-quality fish farms, they are considered one of the best fish for pregnant and breastfeeding women because of their low mercury and contaminant content.
Tilapia are painted on ancient Egyptian tomb walls and included in a spell in the Egyptian Book of the Dead to help the deceased take his or her place in the sun boat.
Because it is easy to prepare and cook on a mass scale, tilapia has been nicknamed "aqua-chicken."
Tilapia have often been represented as the aquatic chicken, and it's perfectly justified.
There over 100 species of true tilapia as well as a number of hybrids.
To ensure that a tilapia crop is male, some farmers use a hormone called methyltestosterone. Although the FDA claims the fish are safe, some buyers refuse to use the treated fish.
Some sushi restaurants use tilapia as a substitute for red snapper because it is more mild and sweet.
In tropical regions, tilapia are often placed in ponds to control algae, duckweeds, and other pond-dwelling plants.
Biblical scholars believe that tilapia was the fish Jesus fed the crowds at the Sea of Galilee, hence its nickname, "St. Peter's Fish."
Tilapia was a symbol of rebirth in Egyptian art. It was also said to join and protect the sun god on his journey across the sky.
Contrary to a popular Internet myth that tilapia is a toxic, "boneless and skinless" fish, tilapia does, indeed, have bones and skin and has no more toxins than other type of fish.
Globally, tilapia production increased about 25% from 2012 to 2015, especially in countries such as Bangladesh, Indonesia, Mexico, and Vietnam.
Tilapia is on the International Union for Conservation (IUCN) list of the 100 Worst Alien Invasive Species.
Since tilapia have such short lifespans, they are more likely to absorb dioxins or mercury than other kinds of fish, including salmon.
In Brazil, scientists are testing tilapia skin as a way to treat burn injuries.
The United States produces about 0.2% of global tilapia supplies.
1"7 Things You Didn’t Know about Tilapia." The Healthy Fish. July 13, 2013. Accessed: December 19, 2019.
2"About Tilapia." About Tilapia. Accessed: December 19, 2018.
3"AquaBounty and Intrexon Developing Gene Edited Tilapia; Receive GMO Exemption." Seafood News. Accessed: December 20, 2018.
4Castrodale, Jelisa. "No, Tilapia Is Not a Mutant, Boneless, Toxic Fish, Despite What the Internet Says." Munchies. Accessed: April 16, 2018.
5Migala, Jessica. "The Truth About Tilapia: How It’s Made, Plus Its Health Benefits, Recipes, and More." Everyday Health. Updated August 24, 2018. Accessed: December 17, 2019.
6Robins, Gay. Women in Ancient Egypt. Cambridge: Harvard University Press, 1993.
7Sussman, Nadia. " Why this Brazilian City Uses Tilapia Fish Skin to Treat Burn Victims." PBS News Hour. March 3, 2017. Accessed: December 21, 2018.
8"Tilapia." FishChoice. Accessed: December 20, 2018.
9"Tilapia." Seafood Health Facts: Making Smart Choices Balancing the Benefits and Risks of Seafood Consumption. Accessed: December 17, 2018.
10"View 100 of the Most Invasive Alien Species." Invasive Species Specialist Group. Accessed: December 21, 2018. | c4 |
There are three weapons used in the sport of fencing. They are Epee, Sabre and Foil. Each has a different target area on which hits are scored. Each weapon has its own unique characteristics which makes the sport as a whole interesting and challenging both physically and mentally.
The Epee is the heavier of the three. It is a thrusting weapon, where only the point is used to score hits. The guard is larger than that of the foil and the blade wider than foil or sabre. The target area is the whole body, Epee is the only one of the three where both fencers can score a hit at the same time.
The Sabre is a cutting and thrusting weapon where the point and edge are used to score hits. The guard is larger than that of the foil but the blade is of a similar width. The target area is anywhere above the waist.
The Foil is a thrusting weapon where only the point is used to score hits. The guard is the smallest of the three weapons and the blade narrow and flexible. The on target area is the torso (the body), arms, legs and head are counted as off target. This is the only one of the three to have a designated off target area. | c4 |
Adorable storage baskets are perfect for storing or displaying toys, clothes and blankets.
They'll make a fun and stylish addition to anywhere in the house. Gorgeous in nurseries, kid's rooms, playrooms and living rooms. Throw the toys in once the kids go to bed, and enjoy!
Care Instructions: Gentle hand wash basket. Remove tassels first. | c4 |
The Capitals have only played in the Stanley Cup Finals once in 1998.
The Capitals have never won the Stanley Cup in the franchise's 43 years.
Washington made it to the Stanley Cup Final once in 1998, when the Detriot Red Wings beat the Caps to win their second consecutive Cup.
The Capitals' Joe Juneau scored an overtime goal in Game 6 of the '98 conference finals to defeat the Sabres and send Washington to the Cup. However, Detroit swept Washington in four games.
Over the next 18 seasons, the Capitals returned to the playoffs 12 times but never advanced to the conference finals.
In 2016 and 2017, the Penguins defeated them consecutively in the second round, but the Capitals kept history from repeating itself this year.
Facing the Penguins again in this season's second round, the Caps won the series 4-2 to send them to the Eastern Conference Finals against the Lightning. | c4 |
I've decided Anya doesn't like ANY of the Council members so we can have a hateful relationship there.
Okay, I'll start a topic!
....What's gonna happen with Cindy and Dim??? | c4 |
Please refresh and try again. Female fitness model excercising in studio with dunbell weights and doing a floor routine of stretches and lifts on a matt. Woman stretching arms before exercise. Smiling sportswoman in sportswear on black background.
Related Posts "Perfect female fitness models" | c4 |
Our digitally-printed wallpaper murals have no limitations to colour, shape or repeats. This means that you almost can use anything at all to create a wallpaper design. All you need to produce your own wallpaper mural is an idea – then we'll help you give it an extra dimension. | c4 |
Why do a course in physics?
Enrolling in a single physics subject is a good way to learn a new discipline, update your professional knowledge, enhance your qualifications or experience university before enrolling in a full degree. There will be a fee and you must gain the approval of the subject coordinator and meet any prerequisites. | c4 |
As the first incorporated city in the state of California, Benicia features some of the most extensive and captivating history, and historical buildings, in all of California. As you walk the streets of our charming historic downtown district, with its rare Victorian and early California architecture, you will be swept back to an engaging time, when day to day life was a struggle but the reward was to watch a city and state being born. We hope you enjoy your walking tour!
was on the west side of First Street on parcels of property known as Semple Slips. Built in the late 1870’s and later used as a rooming house called the Alamo Rooms, this site was famous or infamous as a popular bordello. It now serves as a seafood restaurant.
Port Costa, across the strait, to its present location. Garske’s Marine Services, Inc. and boatyard have occupied the site since 1950.
The Von Pfister Adobe was built in 1847 and was the third building erected in Benicia. Edward Von Pfister operated a general store and saloon in 1848, when a messenger from Sutter’s Mill stopped on his way to Monterey with a sample of gold nuggets. Unable to contain his secret, he informed those present of his precious cargo. Efforts are underway by the Benicia Historical Society to restore this most valuable and historical structure.
Built in 1850-51 and originally located at the East 5th Street wharf, this building served as a hotel for some members of the state legislature during the time when Benicia was California’s third capital. Daniel Hastings moved the present building to this site in 1856. In its colorful history it has served as home to the offices of the “Solano County Herald” newspaper, a butcher shop, a dry goods store, a lawyer’s office, a Chinese lottery, a speak easy during prohibition days, a bordello, an artist studio and a restaurant.
This structure was prefabricated in Maine and reassembled in its present location. The small two-room annex in the rear of the building is believed to have been built here prior to 1848 and contains an original chimney among its other features. Prior to its most recent renovation in 1988, this residence was called the “What Not Shop,” an antique and collectibles store.
This little New England style “salt box” house overlooking the Carquinez Strait is one of several such homes prefabricated on the East Coast and sent in sections to California to be reassembled here during the Gold Rush Days. This home was moved here from Port Costa c 1879 after a disastrous fire destroyed all of the buildings on First Street between “D” and “E” Streets in 1867.
This building, actually two sections of one building, was originally on the west side of First Street, north of “A” Street. A rooming house, this building dates from 1879-1880. It was moved from its location extending over the water. Its current location is between “D” and “E” Streets.
Many legislators resided at the hotel during the months when Benicia was the state’s capital. The register included the names of such famous persons as Ulysses S. Grant, William Tecumseh Sherman, John A. Sutter, Governor Riley, Colonel Silas Casey (the Indian Fighter), F. L. Low (one of California’s governors), Judge Hastings of Hastings Law School fame and many others. Fire razed the hotel in 1945. This site is an example of the mutable nature of Old Town. The second story of the building you see today was moved to this site in 2000. It was previously the second story of the Jurgensen’s Saloon (1892) which was located down First Street north of the S. P. Railroad Depot. A frequent customer at the Jurgensen’s Saloon was the world famous author, Jack London.
This handsome brick building was completed in 1852 for use as a City Hall. It served as the State Capitol Building during 1853 and 1854, when Benicia was the capital of the State of California for a period of 13 months. The Senate Chambers were on the first floor, and the Assembly met on the second floor. In addition, there were several committee rooms. In 1854 the building also housed the State Treasury since no wooden structure was considered safe for this purpose. Historians record that there were good wooden sidewalks from the Capitol building to the town so the building could be reached dry-shod in all seasons.
This charming residence was once a Gold Rush hotel on First Street. Following a fire in 1856 it was purchased by a Swiss-born Benicia merchant, Joseph Fischer, who had the building moved to its present location. Here he had it turned around, added porches, a kitchen, servant’s quarters and privies.
The first Masonic Temple in California was constructed in 1850 on land donated by Alexander Riddell and with lumber donated by Benicia founder Robert Semple.
The lower floor of the building was used as a courtroom and country offices prior to completion of the State Capitol building in 1853. Benicia was the county seat for Solano County at that time. The second floor of this building is virtually unchanged and has remarkably ornate woodwork made by California frontier craftsmen.
Built by Franklin and Henrietta Riddell Fish about 1900, this Queen Anne Victorian home, though a relatively standard design, was unusually wellconstructed.
With restoration, it has survived its rival, the Hastings mansion, visible in the background of this historic photo.
In April of 1849 the Reverend Sylvester Woodbridge, a Presbyterian missionary, became the minister of the first Protestant Church built in California. Here, in a simple Gothic Revival style church, he preached on Sundays, conducted Benicia’s first public day school on weekdays, and slept in a sailor’s hammock in the building at night.
Historians record that the reverend’s sympathies with the South during the Civil War caused dissension among the members of his congregation, causing his departure and the eventual closing of this church in 1871. Today, the site is a City Park and gateway to Old Town Benicia.
In 1854 Mother Mary Goemaere, a French-born Dominican nun, arrived in Benicia by chartered schooner from Monterey, establishing St. Catherine’s Academy at this site.
Begun initially as a girls’ boardschool, the Academy became a co-educational boarding and grammar school in 1889. St.
Catherine’s served educational needs of this area for over 100 years. It was razed in 1965 to make way for a shopping center.
This colonial Revival house, with a deep-set portico and a vertical emphasis in its design, was build for H. Kullman, owner of Kullman-Salz Tannery in 1907. Later sold to J.L.
Sanborn, it has been for many years an antique store operated by the Lundin family.
In 1864 Captain Julian McAllister purchased a typical New England salt box home build in 1790 in Torrington, Connecticut, had it dismantled and shipped it around the Horn to San Francisco. From the Bay it was floated by barge on the Carquinez Strait to Benicia and reassembled at its present site. The rectory still has its original fireplace and staircase. In 1865 a master bedroom and kitchen were added.
The present church was built in 1859. Lay readers conducted the early services, among them Captain Julian McAllister. In 1876 St. Paul’s became the first Episcopal Cathedral for Northern California with the Reverend J.H.D. Wingfield as bishop.
Work on the building was done by Scandinavian shipwrights from the Pacific Mail and Steamship Company.
The nautical heritage is reflected in the ceiling, which resembles an inverted ship’s hull and is similar in design to the Norwegian Stave Churches. California redwood with wooden dowels is used in this edifice, which has a floor plan shaped like a cross.
This building, which was built by the Singler family as a barbershop in 1894, is an excellent example of a typical wood frame commercial building in pre-1900 downtown Benicia.
Utilized as a barbershop for nearly 50 years and then as a café, saloon, variety store and a card room, it was restored completely in 1989. It is now a tearoom featuring a design ceiling by Benicia’s own Bradbury & Bradbury Art Wallpapers.
Built by Simon Johnston, this building was first a grocery store, but later and for most of its history it was the home of the Royal Bakery. The building materials included sandstone blocks quarried from a gravel pit near the corner of East 4th and H Streets. The Greek Revival detail of the façade above the main entrance is a copy of the old State Capitol across the street. across the street.
The town jeweler from the 1880’s until 1935, Frank Stumm, the founder’s son, was a prolific photographer and provided many postcard views of Benicia between 1906 and 1918. The original building was both the family home and the store.
By 1879, several tanneries were operating in Benicia, chief of which was the Kullman-Salz firm, which handled about 1,000 hides daily making Benicia the principal tanning center of the Pacific Coast. Over onethird of all leather processed in California was tanned here.
Operations were terminated in 1929. | c4 |
Recovery is hard and so is hanging out at the hospital the whole time. I have established 10 things that … Continue reading 10 helpful tips to make a hospital stay a bit better.
We have a major surgery coming up. I have diaper bags packed, car cleaned with stroller loaded, and all instructions … Continue reading Sure ways to prepare. | c4 |
Judd Lienhard is a former US Army Rangers officer with multiple tours in Iraq and Afghanistan. He’s had an active interest in history since his youth and very much enjoys writing pieces about lesser-known history and his world experience, which tie into and bring perspective to current events.
Trump Doesn’t Know Much about History…or Does He? | c4 |
the goat is small does not mean it is a pygmy.
and muscular than the Nigerian Dwarf.
pygmy goat is considered a disqualification.
the National Pygmy Goat Association.
with resources and shows all over the country. | c4 |
I am so happy that she was found not guilty! She didn’t deserve to be on trial. She loved Caylee so much and everyone knew. The world just loves drama so much.
Love these pics. Casey was such a good mommy. How Nancy Grace, or anyone, can look at these and still think she’s guilty is beyond me.
It’s clear to me that little girl was loved. How anyone can see the mom-and-daughter pictures and think Casey killed her is beyond me. | c4 |
Ever wonder how much protein you need in your diet? Click on our calculator to find out!
Check out our blog with health and workout tips to help you reach your goals. | c4 |
Most plants grow their foliage first, and then grow their blooms. Trees do it backwards.
What backwards thing have you noticed lately? | c4 |
Welcome to second grade. This year we will be learning many new and exciting things. We will become proficient in reading. We will become published writers. In Math, we will be mastering addition and subtraction, as well as many other concepts. In Social Studies we will be learning about our community of Saugerties. | c4 |
Home/Dementia/Oh yeah, this study is *sooooo* helpful….
Oh yeah, this study is *sooooo* helpful….
The inability to detect sarcasm may be an early warning sign of dementia.
By Stephanie Sarkis|2016-10-05T06:45:48-04:00April 19th, 2011|Categories: Dementia|Tags: Alzheimers, brain, Dementia, frontal lobe, lying, memory, sarcasm|Comments Off on Oh yeah, this study is *sooooo* helpful…. | c4 |
Are you making the most out of your microwave?
Is plastic microwave cookware safe ?
Is this dish safe for use in my microwave? | c4 |
Off white birds, mid-flight, on a light brown background. This is our ever popular print, Flight 2! Paired with Espresso brown straps and for the first time, Espresso Koolnit! | c4 |
Microbe-Lift Legacy Cold Weather Koi & Goldfish Food - 2 lbs. 4 oz.
Microbe-Lift Legacy Cold Weather Koi & Goldfish Food - 5 lbs. 4 oz. | c4 |
Filming has begun on the seventh season of Call the Midwife!
The BBC drama launched in 2012 and is one of the most watched dramas in the UK, regularly gaining over 10 million viewers each week.
This year’s Christmas special will air in the US in December and PBS has confirmed that Season 7 will air in spring 2018, shortly after its UK debut.
Buy the Season 6 box set on Amazon here.
Written by Call the Midwife creator Heidi Thomas, the holiday episode will open with Poplar under a thick blanket of snow, as the midwives face the challenge of the coldest winter for 300 years.
The winter of 1963 saw temperatures plunge to a record low and the whole country brought to a standstill due to the severe weather. Battling against snow, ice, power cuts and frozen pipes, the midwives strive to provide the best possible care for their patients.
Valerie helps a young couple, newly arrived in London, who experience a traumatic birth, and Sister Julienne strives to reunite a family torn apart by a tormenting father.
The Christmas special guest stars EastEnders actress Anita Dobson.
← Will there be a fifth season of ‘Endeavour’?
‘Call the Midwife’ will continue for at least another THREE seasons!
4th March 2019 Editor Comments Off on ‘Call the Midwife’ will continue for at least another THREE seasons! | c4 |
I don't get the expired card message so, I can't ask for a new one, what should I do?
¿Por qué ya no puedo enviar dinero a usuarios Payoneer?
ATM charged but didn't dispense cash. | c4 |
Take that: the speed limit on Canadian highways is 100 km/h. And they`re built so wide and spacey that in Italy you would fit five cars next to each other on one lane. Not that I exactly miss being passed on the right side, but being a criminal for going over a 100 km/h?
Talking about driving habits: sooner or later I`ll for sure indulge in writing about my first experiences with a BIG truck in Canada. And parking it. Or driving a car with a German license plate on a mountain road in South Tyrol. Italian campers cramming Munich’s city streets around Oktoberfest time. Danish patience and toll-station-wack-outs. Another time. | c4 |
Cut 3 shallow slits on each side of both trout. In a medium bowl, mix onion, garlic, herbs, chilli, lemon juice and oil. Use 1/2 of the onion mixture to fill cavity of both trout, massaging into fish. Place lemon slices in each cavity. Transfer to a roasting pan that comfortably fits both trout. Rub remaining onion mixture into outside of trout and into slits.
Season well with sea salt flakes and freshly ground black pepper. Pour fish stock into pan and surround trout with tomatoes. Drizzle with extra oil.
Bake for 20 minutes or until trout is cooked when tested with a fork. Garnish with herbs and serve. | c4 |
A karyotype reers to the number, size and pattern of the chromosomes in an individual's cells. Chromosomes become visible in a cell's nucleus during the process of cell division. This process is arrested, and a dye is applied to enhance the appearance of the chromosomes. In order to make the karyotype, the chromosomes are grouped in pairs by size. Differences between the chromosomes can reveal genetic abnormalities. | c4 |
5 rounds of focused breathing. Watch and notice your inhalations and exhalations.
10 rounds of regulation breath. Lengthen and smooth out the breath in each direction.
Seated or standing Sun Breaths, taking arms overhead on inhale with palms up. Releasing arms by side on exhale. Lengthen spine. Gaze follows finger tips overhead. | c4 |
A friend just shared this video and I'm sharing it with you.
I don't know about you, but I've been trying to meditate for years and always have an 'excuse' for not doing so.
Enjoy it and have a good day.
Love this video! It definitely captures what meditation can do for you for one minute or more..its really not about time...but one minute is better than nothing thats for sure! And one moment meditation every moment is the ultimate! | c4 |
Brett was born on December 22nd, 1981 in Denver. Brett's father is Ronald (Ron) Edward Costello and his mother is <Unknown>. His paternal grandfather was Edward John Costello and his paternal grandmother is Harriet Emma Mawson. He has a brother named Erik. He is the younger of the two children. | c4 |
The flag of the Seychelles was adopted on June 18, 1996. The oblique bands symbolise a dynamic new country moving into the future. The color blue depicts the sky and the sea that surrounds the Seychelles. Yellow is for the sun which gives light and life, red symbolises the people and their determination to work for the future in unity and love, whilst the white band represents social justice and harmony. The green depicts the land and natural environment.
The original flag was adopted at independence on June 29, 1976. In 1977, when president James Mancham was overthrown by France-Albert René, the old flag was abolished and the red, white and green flag of the Seychelles People's United Party came into use. | c4 |
Map editor allows you add new places to the map, and edit existing ones directly from the app.
Do I have to be online/registered with OpenStreetMap.org before I can add or edit info on the map?
How can I edit existing places or address info on the map?
How can I add a new place to the map?
How can I move or delete places on the map?
When will my edits be available on OSM and for other MAPS.ME users?
I can’t log in with my account or send my edits to OSM. | c4 |
Noah is a teacher and occasional writer. He eats really spicy food, and wishes he still had time for gaming. He has a dog named Porkchop, but no, he's not named after "Doug." Find him on Twitter @the_half_korean. | c4 |
Infant tubs hold a small amount of water that gets dirty and gross during bathing. After months of research and dozens of focus groups, we came up with an extremely complex solution. Why not poke a hole in the side of the tub so dirty water can drain out while fresh water flows in?
Cleaner water. Cleaner baby. Perfect. | c4 |
Students will love this book and activity. Map skills, counting, and following directions are reinforced.
Have each student press out their biscuit.
Take one apple from the filling and place to one side.
Sprinkle cinnamon and sugar over the apple.
Sprinkle cinnamon and sugar over the top.
Bake according to the biscuit package and enjoy. | c4 |
MG-28 – Did Joseph Smith Translate Fraudulent Plates?
The Church now admits that Joseph Smith’s translation of this image does not match the translation given by Egyptologists. Likewise, the date these manuscripts were written proves that they were not in existence during Abraham’s lifetime. So, even if we could find the missing fragments, these couldn’t contain Abraham’s words as translated by Joseph Smith.
← MG-27 – Did Joseph Smith Change God’s Revelations? | c4 |
Sipping Chardonnay with Marvin Straight.
a Frenchman with a henchman.
Passing away while playing Madden 28. | c4 |
Is it true that he sold his limousine?
I do not know if it is true that he sold his limousine.
Does he know how much this car is?
Why was the ice melted?
I don't know why the ice was melted.
Who has turned the light off?
Do you know who has turned the light off?
Will they come on time?
I don't know if they will come on time.
I don't know what you had for breakfast.
How many colors do they use?
I don't know how many colors they use. | c4 |
Get more people, especially men, to start baking.
Show how baking is fun and inspire others, in short words.
That is yet to be found out! | c4 |
Sit on the floor and extend your legs in front of you bend your legs slightly, keeping heels on the floor.
Grasp beneath your legs just above your knees.
Keeping your chin slightly pointed towards your chest round your shoulders forward as you lean back towards the floor.
Hold position for 10 seconds then roll slowly up out of position and repeat. | c4 |
Even when we’re out jogging to escape our overly hectic schedules, the moment we stop, we are racing against the clock of them.
It’s so much easier to finish a run and just move on with the day. Forgetting (whether it’s an accident or on purpose) to stretch will, over time, be detrimental to your body.
Sometimes, we just don’t have time. | c4 |
Cynthia Wilson James was always sure about two things: She wanted a husband who shared her spiritual beliefs, and she wanted to have more than one child with him.
And just because she didn't reach that first goal until she was 40 didn't mean the second one was out of reach.
The Columbia, S.C., woman, now 52 years old, conceived her first daughter, who just turned ten years old, around her first wedding anniversary.
Daughter number two, who turned eight years old in January, was conceived less than two years later. | c4 |
No, not your hair but your foods! Eat more energy-dense foods such as fruits, vegetables and whole grains versus low nutrient foods such as chips, soda, candy, white starches, etc.
In a recent study published in the June issue of the Journal of Food Chemistry and Analysis, most Americans get one-third of their calories from junk food! Yikes! This could result in some major weight loss. Depending upon your calorie intake this could result into a five pound weight loss each month! No wonder they call it junk!
Make the most of your calories!!
Guess the amount of calories?
Actually they are the SAME at 1200 calories!!! | c4 |
If you have time to breathe you have time to meditate. You breathe when you walk. You breathe when you stand. You breathe when you lie down.
Learn with us various meditation techniques and practise them in your day to day life!
Meditation on Love and relationship. | c4 |
These are really cute, especially when serve with fresh sliced fruit or berries.
Cut out gingerbread men using a cookie cutter.
Dip them in egg and then sprinkle with a light layer of sugar.
In a buttered pan, fry them until golden on both sides. | c4 |
It’s strange but I find this almost... Arousing. Buckle in Oppo, it’s about to get weird!
This cover reminds me of a form-fitting dress or tight pants. You pick the one that’s more applicable. Sure, naked is beautiful but this leaves something to the imagination. | c4 |
Warm-up: Flowing yoga inspired poses that will warm up your muscles as you become accustomed to standing on the BOSU Balance Trainer's dynamic surface.
Segment One: Standing exercises and poses that alternate toning and balance exercises with stretching to tone your lower body and core.
Segment Two: Focus on your upper body in a series of fluid movements that target your muscles in a unique and very challenging workout.
Segment Three: Pilates inspired balance routine recruits your core muscles as stabilizers. Your ab and back muscles will fire constantly in this non traditional and very challenging workout! | c4 |
It’s official – I now work at a standing desk in my home office. I love walking right up to my computer instead of plopping down in a chair. And it’s not just any standing desk, either; my desk is an Ikea hack. It’s fashioned from IKEA bookcases with a keyboard tray added on. It looks sleek and pro, allows me to sit and stand, and cost less than $300.
It’s early yet – I’ve only had my new desk a few days. I admit I’m a little excited-scared about working standing up – will I get fatigued? Will I be able to concentrate as well? What unforeseen aches and pains might it cause? These are questions I’ll be able to answer soon.
If you’re considering a standing desk, check out why I chose this option and how to do it yourself. I’m hesitant to even call this desk a hack because it looks so good!
Women who sit for more than six hours a day were about 37% more likely to die during the course of a 14-year period than those who sat fewer than three hours per day. Men were about 20% more likely to die .
Over time, the extra calories burned by standing up do add up! Check out this calculator to see.
Standing requires more energy as you tense your legs and core and use small stabilizer muscles to stay upright. Standing gives you a better opportunity to use good posture because you’re not dependent on an ergonomic chair.
Sitting all day is a major cause of inactive glutes, tight hips, rounded shoulders, and low-back pain.
All of these reasons and more convinced me I should give standing up a try.
Of course, you don’t have to stand up all day to benefit from less sitting. You can integrate more standing into your day even if you’re chair-bound by walking or standing every 30 minutes or standing more in everyday activities (waiting in line, talking on the phone, watching TV).
After much reading I also believe a combination of sitting and standing at work is ideal. I now have both options.
Have you ever seen store-bought standing desks? Unless you want to spend a small fortune, most look about as utilitarian as it gets. I was inspired by this video explaining how to make a standing desk from IKEA bookcases. I love the look, plus it has lots of storage space. It consists of three IKEA Expedit bookcases (one 17 3/8×72 7/8″ unit and two 31 1/8×31 1/8″ units).
Since I want to sit and stand, we installed a second monitor on a separate desk which can be used with the same computer. All I have to do is grab whatever applications I need with the mouse and drag them onto the second screen. Then I move my wireless keyboard to my desk to sit down to start working (see top picture). It’s really quite simple!
The main obstacle with a hack standing desk is ensuring you have a keyboard tray that’s ergonomic. In our case, we bought this 3M adjustable keyboard tray and ended up installing it upside down to make it work. I’m on the short side (5’2″), and if we’d installed it from the top as it was designed, it wouldn’t have been low enough. Even now it’s only the right height when I’m wearing my Dansko clogs. So we’re looking into an anti-fatigue mat that might add an inch under my feet.
Know the proper ergonomic heights for you and measure carefully for a keyboard tray that adjusts to the right height. Most trays don’t move up or down more than about 5 inches.
We also used plastic tubing from IKEA to hide cords and some wicker baskets for storage.
Everything I’ve read says to sit as well as stand to avoid mega fatigue. It’s worth it to try and wrangle this.
If you have leg or foot problems, assess whether you can handle long periods of standing.
Buy an anti-fatigue mat with foam or gel. I haven’t bought one yet so I don’t know which is better.
Slouching while standing. Don’t lean on one leg or prop an elbow up on the desk. Bad posture while standing defeats the purpose of a standing desk and can cause new problems (neck, hip, or back pain). Stand straight and tall, shoulders down and back, abs pulled in. Keep your chin tucked towards your chest so you’re not looking up at the monitor.
Ergonomics. Your keyboard height must put your arms at a 90-degree angle and your eyes should be looking directly at the middle of the screen. Check out this calculator to learn more.
Trying to do it all too fast. Think of standing up like converting to barefoot running. It’s a process that takes adjustment and is best done slowly. You may never stand up all day, but I know people who do!
I’m excited about this new setup! Let me know if you have a standing desk or whether you’ve considered hacking your own.
This entry was posted in Trying New Things and tagged Glutes, Stabilization. Bookmark the permalink.
I told my husband that I wanted one for Christmas (and actually picked out the one I wanted). It is portable which I love and adjustable. I love standing during the day – and lots of times I walk forward and back between hitting enter or even just walk in place – so much better than sitting!!!
Sweet Kim! I’m so happy you’re finding success with it. I’m new to standing up all day but so far, it only takes a little sitting to rejuvenate me.
Sounds like an opportunity Sarah :).
What a great & detailed post about all the info needed to not only make but know how to use it! GREAT POST Suzanne!!!!
Thanks so much Jody! It was easy to write… I love this solution!!
I wasn’t enthused for many years about standing up. But the study showing women’s mortality from sitting was the final piece of convincing I needed!
That’s quite a fine looking piece of office furniture you have there, much better than my first creation!
I created my first desk monster after realized that 95% of my ‘work from home’ time was spent at the snack bar in the kitchen. After spending all day sitting down at my day job, the last thing I wanted to do was come home and sit yet again (my body spoke – I listened).
I’ve moved on or I guess you could say “up” now, but they’re will always be a special place in my heart for my first Frankendesk.
FYI – The anti-fatigue mats definitely come in handy, and are worth every penny.
Haha! Thanks Matt… I am so glad you’ve moved up from a Frankendesk. I always think I’ve heard it all when it comes to standing desk hacks, but I’m continously surprised at people’s ingenuity. Here’s to standing!
Gotta give my husband credit for ALL the work!
I love it!!!! Looks awesome!!!
Love this! As a physician I spend a lot of time at my desk doing notes and have looked into buying one of these. I have a few doctor friends using them and they love them. They also make a bike desk so you can pedal rather than walk. Can’t wait to hear what you think about it. I always tell my patients their body was made to move so move it as much as you can.
Hey Kelli! I couldn’t agree more about the body being made to move. The more low-intensity movement the better, with some high-intensity thrown in! I’ve never heard of the bike desk – sounds like the ultimate way to stay fit while working though!
Well this is exciting, for once I’m doing something right. And on accident! I’m a personal chef so I work on my feet anyway, but my laptop is on a high kitchen counter so I do paperwork etc standing also. Anti-fatigue mat is a good suggestion, also like anything, good shoes are critical!
I’m mind-blown, seriously! I alternate between sitting and standing, and this looks like something easy enough to set up in my apartment. Certainly a good alternative to costly standing desks. Thanks for the inspiration!
I’m so glad you like it, Philip! Good luck :).
Your standing desk looks super cool. I have an arrangement with a carton on top of a regular desk for my keyboard, and a taller box (actually a metal thing designed to hold bread, standing on its end) to raise up my screen. But it’s not too comfortable, and not as inviting as the chair. With one like yours, I’d surely use it more often.
I also built the Ikea version with a 7 1/2″ shelf and using it for about fourteen days. I stand the greater part of the day and I use a $35 drafting chair whatever remains of the time.
I have 2 fake hips and joint pain in one that had abandoned me with a dull hurt in the hip. The hurt has left since I began working in the standing position without shoes. I don’t know whether running shoeless has assisted with that. I was really happy with my work since I read this article. I think I should read it 14 days ago to build one like yours. Great job….
Hey Roy – Nice! I’ve heard running shoes may cause problems for some people. I have to wear supportive shoes and have had the same Dansko clogs for 10 years :). I’m glad you got something out of my experience! | c4 |
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