Datasets:
pgs_id large_stringlengths 9 9 | ppm_id large_stringlengths 9 9 ⌀ | pss_id large_stringlengths 9 9 ⌀ | pgp_id large_stringclasses 762 values | trait_reported large_stringlengths 2 200 | covariates large_stringclasses 843 values | pmid int64 18.4M 41.4M ⌀ | doi large_stringclasses 756 values | or_estimate float64 -0.09 111 ⌀ | or_ci_lower float64 -0.17 25.3 ⌀ | or_ci_upper float64 -0.01 1.28k ⌀ | or_se float64 0.04 1.07 ⌀ | hr_estimate float64 0.11 5.35 ⌀ | hr_ci_lower float64 0 4.97 ⌀ | hr_ci_upper float64 0.16 34.4 ⌀ | hr_se float64 0.06 0.08 ⌀ | beta_estimate float64 -10 370 ⌀ | beta_ci_lower float64 -9.28 23.3 ⌀ | beta_ci_upper float64 -3.8 42.8 ⌀ | beta_se float64 0 123 ⌀ | auroc_estimate float64 0.13 84.2 ⌀ | auroc_ci_lower float64 0 0.98 ⌀ | auroc_ci_upper float64 0.22 737 ⌀ | auroc_se float64 0.01 0.06 ⌀ | cindex_estimate float64 0.53 632 ⌀ | cindex_ci_lower float64 0.48 0.89 ⌀ | cindex_ci_upper float64 0.53 0.92 ⌀ | cindex_se float64 0 0.03 ⌀ | n_individuals int64 22 5.33M ⌀ | ancestry_broad large_stringclasses 63 values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PGS004322 | PPM020429 | PSS011358 | PGP000555 | Incident ischaemic stroke | age, gender, 10-yr ASCVD Risk by PCE, genetic background, and sepsis | 36,926,049 | 10.3389/fcvm.2023.1076745 | null | null | null | null | 1.26 | 1.17 | 1.35 | null | null | null | null | null | null | null | null | null | null | null | null | null | 454,493 | European |
PGS004873 | PPM021165 | PSS011635 | PGP000618 | Incident RA | PCs 1-10 | 38,866,767 | 10.1038/s41467-024-48938-2 | null | null | null | null | 1.87 | 1.76 | 1.99 | null | null | null | null | null | null | null | null | null | null | null | null | null | 447,332 | European |
PGS002307 | PPM013044 | PSS009665 | PGP000329 | Incident gout | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI) | 35,484,537 | 10.1186/s12916-022-02341-0 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 416,481 | European |
PGS004695 | PPM020881 | PSS011440 | PGP000598 | Incident idiopathic pulmonary fibrosis | Age, sex, education level, smoking status, pack-years of smoking, BMI | 37,414,299 | 10.1016/j.chemosphere.2023.139362 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 402,042 | European |
PGS004753 | PPM020978 | PSS011490 | PGP000604 | Current smoker | age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 | 38,508,198 | 10.1016/j.xgen.2024.100523 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 9,316 | European |
PGS005132 | PPM022352 | PSS011918 | PGP000703 | Asthma | age, sex, 20 genetic principal components | 36,778,051 | 10.1016/j.xgen.2022.100212 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 8,741 | European |
PGS004930 | PPM021718 | PSS011762 | PGP000665 | Celiac disease | null | 39,218,908 | 10.1186/s40246-024-00664-y | 1.52 | 1.35 | 1.71 | null | null | null | null | null | null | null | null | null | 0.67 | null | null | null | null | null | null | null | 8,417 | European |
PGS000539 | PPM001224 | PSS000549 | PGP000118 | Breast cancer [female] | age, sex, batch PCs 1-4 | 32,991,828 | 10.1016/j.ajhg.2020.08.025 | 1.585 | 1.489 | 1.687 | null | null | null | null | null | 0.46 | null | null | 0.0319 | 0.624 | 0.607 | 0.641 | null | null | null | null | null | 7,785 | European |
PGS003195 | PPM016106 | PSS010018 | PGP000393 | Vitamin D | SEX,AGE,Batch,PC1,PC2,PC3,PC4 | 36,152,628 | 10.1016/j.ajhg.2022.09.001 | null | null | null | null | null | null | null | null | 1.49 | null | null | 0.107 | null | null | null | null | null | null | null | null | 6,926 | European |
PGS001801 | PPM009320 | PSS007722 | PGP000264 | Chronic obstructive pulmonary disease (moderate-to-severe) | Age, sex, height, smoking pack-years, PCs of genetic ancestry, study clinic, PRS_FEV1 | 32,649,918 | 10.1016/s2213-2600(20)30101-6 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 19,229 | European |
PGS000662 | PPM001365 | PSS000596 | PGP000122 | Prostate Cancer | Age, 10 PCs | 33,398,198 | 10.1038/s41588-020-00748-0 | null | null | null | null | null | null | null | null | null | null | null | null | 0.833 | null | null | null | null | null | null | null | 199,969 | European |
PGS002029 | PPM011106 | PSS009291 | PGP000263 | Disorders of lipoid metabolism | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 20,000 | European |
PGS002002 | PPM010891 | PSS009486 | PGP000263 | Hair colour (natural, before greying) | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 19,713 | European |
PGS001897 | PPM010059 | PSS009393 | PGP000263 | Skin colour | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 19,738 | European |
PGS002020 | PPM011034 | PSS009282 | PGP000263 | Benign neoplasm of other parts of digestive system | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 19,463 | European |
PGS001810 | PPM009382 | PSS009280 | PGP000263 | Polycythemia vera | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 19,539 | European |
PGS003555 | PPM017483 | PSS010921 | PGP000457 | Waist circumference | sex, age, deprivation index, PC1-16 | null | 10.1101/2022.09.28.509988 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 19,954 | European |
PGS000893 | PPM002623 | PSS001165 | PGP000230 | Baseline LDL cholesterol | sex, batch, age at initial assessment, PCs1-4 | 34,887,591 | https://doi.org/10.1038/s41586-021-04064-3 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 389,158 | European |
PGS004045 | PPM019686 | PSS011228 | PGP000517 | Chronic kidney disease or dialysis | 0 | 38,908,374 | 10.1016/j.ajhg.2024.06.003 | 1.199055 | 1.174642 | 1.223976 | null | null | null | null | null | 0.181534 | 0.160964 | 0.202105 | null | 0.5508 | 0.544895 | 0.556704 | null | null | null | null | null | 383,843 | European |
PGS001786 | PPM009290 | PSS007709 | PGP000262 | Appendectomy | sex,age,age2,age*sex,age^2*sex, 20PCs | 36,777,179 | 10.1016/j.xgen.2022.100241 | null | null | null | null | null | null | null | null | null | null | null | null | 0.574 | null | null | null | null | null | null | null | 357,112 | European |
PGS004908 | PPM021361 | PSS011702 | PGP000640 | Kidney cancer | Age, sex, PCs, BMI, smoking, hypertension | 38,671,320 | 10.1038/s41588-024-01725-7 | 1.5 | 1.43 | 1.58 | null | null | null | null | null | null | null | null | null | 0.74 | 0.72 | 0.75 | null | null | null | null | null | 324,805 | European |
PGS003993 | PPM019951 | PSS011235 | PGP000517 | T1D | 0 | 38,908,374 | 10.1016/j.ajhg.2024.06.003 | 2.378173 | 2.30792 | 2.450565 | null | null | null | null | null | 0.866333 | 0.836347 | 0.896318 | null | 0.733639 | 0.726144 | 0.741133 | null | null | null | null | null | 322,349 | European |
PGS005088 | PPM022168 | PSS011826 | PGP000680 | Epithelial ovarian cancer | null | 41,266,372 | 10.1038/s41525-025-00529-w | 1.45 | null | null | null | null | null | null | null | null | null | null | null | 0.604 | null | null | null | null | null | null | null | 245,377 | European |
PGS001357 | PPM021433 | PSS011747 | PGP000656 | Type 2 diabetes | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | null | 10.1101/2024.08.22.24312440 | 1.8 | 1.77 | 1.84 | null | null | null | null | null | null | null | null | null | 0.739 | 0.734 | 0.743 | null | null | null | null | null | 245,177 | European |
PGS003020 | PPM015896 | PSS010030 | PGP000393 | Hypertension | Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 | 36,152,628 | 10.1016/j.ajhg.2022.09.001 | 0.992 | 0.98 | 1.003 | null | null | null | null | null | -0.00832 | null | null | 0.00587 | 0.506 | 0.503 | 0.509 | null | null | null | null | null | 203,639 | European |
PGS003068 | PPM015989 | PSS010027 | PGP000393 | Smoking Status | Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 | 36,152,628 | 10.1016/j.ajhg.2022.09.001 | 1.643 | 1.627 | 1.659 | null | null | null | null | null | 0.497 | null | null | 0.00497 | 0.633 | 0.63 | 0.635 | null | null | null | null | null | 203,428 | European |
PGS003110 | PPM016006 | PSS010036 | PGP000393 | Type 2 Diabetes | Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 | 36,152,628 | 10.1016/j.ajhg.2022.09.001 | 1.406 | 1.378 | 1.435 | null | null | null | null | null | 0.341 | null | null | 0.0103 | 0.594 | 0.588 | 0.6 | null | null | null | null | null | 203,197 | European |
PGS002792 | PPM015449 | PSS009955 | PGP000371 | Prostate cancer risk | disease diagnostic age or age at recruitment, subgroups and 10 principal components | 35,996,327 | 10.1002/pros.24431 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 3,008 | African American or Afro-Caribbean |
PGS003877 | PPM018769 | PSS011097 | PGP000501 | HDL cholesterol | age, sex, array version, and the first 10 principal components of ancestry | 37,852,978 | 10.1038/s41467-023-41985-1 | null | null | null | null | null | null | null | null | 3.67 | null | null | 0.27 | null | null | null | null | null | null | null | null | 2,669 | Greater Middle Eastern (Middle Eastern, North African or Persian) |
PGS003891 | PPM018783 | PSS011097 | PGP000501 | Height | age, sex, array version, and the first 10 principal components of ancestry | 37,852,978 | 10.1038/s41467-023-41985-1 | null | null | null | null | null | null | null | null | 0.026 | null | null | 0.0013 | null | null | null | null | null | null | null | null | 2,669 | Greater Middle Eastern (Middle Eastern, North African or Persian) |
PGS002060 | PPM011342 | PSS009323 | PGP000263 | Nasal polyps | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 19,106 | European |
PGS002182 | PPM012303 | PSS009453 | PGP000263 | Gamma glutamyltransferase | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 18,990 | European |
PGS001895 | PPM010043 | PSS009391 | PGP000263 | Cholesterol | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 19,002 | European |
PGS003272 | PPM015708 | PSS010025 | PGP000393 | Creatine | Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 | 36,152,628 | 10.1016/j.ajhg.2022.09.001 | null | null | null | null | null | null | null | null | -0.267 | null | null | 0.0343 | null | null | null | null | null | null | null | null | 195,036 | European |
PGS000330 | PPM000887 | PSS000448 | PGP000100 | Type 2 diabetes (incident and prevalent cases) | genotyping array/batch, 10 ancestry PCs, stratified by sex | 32,273,609 | 10.1038/s41591-020-0800-0 | null | null | null | null | 1.74 | 1.72 | 1.77 | null | null | null | null | null | null | null | null | null | null | null | null | null | 135,300 | European |
PGS004251 | PPM020315 | PSS011329 | PGP000542 | Prostate cancer | first 10 genetic principal components | 37,087,533 | 10.1038/s41698-023-00377-w | null | null | null | null | 1.78 | 1.72 | 1.85 | null | null | null | null | null | null | null | null | null | null | null | null | null | 115,207 | European |
PGS005260 | PPM022743 | PSS012069 | PGP000748 | thyroid carcenoma | null | null | 10.1101/2025.05.15.25327513 | 1.960191 | null | null | null | null | null | null | null | 0.673042 | null | null | null | 0.684523 | null | null | null | null | null | null | null | 94,651 | African American or Afro-Caribbean, Hispanic or Latin American, European |
PGS005274 | PPM022757 | PSS012069 | PGP000748 | thyroid carcenoma vs benign nodular goiter | null | null | 10.1101/2025.05.15.25327513 | 1.493462 | null | null | null | null | null | null | null | 0.401097 | null | null | null | 0.613489 | null | null | null | null | null | null | null | 94,651 | African American or Afro-Caribbean, Hispanic or Latin American, European |
PGS000731 | PPM001671 | PSS000873 | PGP000138 | Squamous cell carcinoma | null | 33,420,020 | 10.1038/s41467-020-20246-5 | 1.44 | 1.41 | 1.48 | null | null | null | null | null | null | null | null | null | 0.605 | null | null | null | null | null | null | null | 88,924 | European |
PGS003043 | PPM015930 | PSS010031 | PGP000393 | Polyunsatturated Fatty Acids | Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 | 36,152,628 | 10.1016/j.ajhg.2022.09.001 | null | null | null | null | null | null | null | null | -0.00329 | null | null | 0.0248 | null | null | null | null | null | null | null | null | 87,079 | European |
PGS003593 | PPM018319 | PSS010958 | PGP000464 | Right granule cell and molecular layer of the dentate gyrus head volume | sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components | 37,337,106 | 10.1038/s41588-023-01425-8 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1,999 | East Asian |
PGS003695 | PPM018339 | PSS010958 | PGP000464 | Left parasubiculum volume | sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components | 37,337,106 | 10.1038/s41588-023-01425-8 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1,999 | East Asian |
PGS003629 | PPM018387 | PSS010958 | PGP000464 | Left CA3 body volume | sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components | 37,337,106 | 10.1038/s41588-023-01425-8 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1,999 | East Asian |
PGS002175 | PPM012247 | PSS009448 | PGP000263 | Speed of sound through heel | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 11,504 | European |
PGS002231 | PPM012694 | PSS009497 | PGP000263 | Qualifications (years of education) | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 16,350 | European |
PGS004925 | PPM021707 | PSS011755 | PGP000660 | Incident coronary heart disease | Sex, genotype array type, 10 PCs | 37,614,046 | 10.1111/joim.13715 | null | null | null | null | 1.63 | 1.49 | 1.78 | null | null | null | null | null | null | null | null | null | null | null | null | null | 77,500 | European |
PGS003406 | PPM017048 | PSS010105 | PGP000423 | Aneurysmal subarachnoid hemorrhage hazard | sex, systolic blood pressure, cigarette packs per day | 36,655,558 | 10.1161/strokeaha.122.040715 | null | null | null | null | 1.344 | null | null | null | null | null | null | null | null | null | null | null | 0.652 | null | null | null | 69,396 | European |
PGS000496 | PPM001181 | PSS000570 | PGP000118 | Breast cancer [female] | age, sex, batch PCs 1-4 | 32,991,828 | 10.1016/j.ajhg.2020.08.025 | 1.323 | 1.289 | 1.358 | null | null | null | null | null | 0.28 | null | null | 0.0133 | 0.576 | 0.568 | 0.583 | null | null | null | null | null | 68,531 | European |
PGS004267 | PPM020335 | PSS011346 | PGP000546 | Gout | age, sex, PC1-10 | 38,811,555 | 10.1038/s41467-024-48654-x | null | null | null | null | null | null | null | null | null | null | null | null | 0.79692 | null | null | null | null | null | null | null | 67,428 | European |
PGS001273 | PPM008867 | PSS004373 | PGP000244 | Osteoporosis | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | 0.7643 | 0.75478 | 0.77381 | null | null | null | null | null | 67,425 | European |
PGS001256 | PPM008789 | PSS004338 | PGP000244 | Gallstones | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | 0.67227 | 0.66315 | 0.68138 | null | null | null | null | null | 67,425 | European |
PGS001274 | PPM008872 | PSS004247 | PGP000244 | TTE osteoporosis without pathological fracture | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | 0.77492 | 0.76604 | 0.7838 | null | null | null | null | null | 67,425 | European |
PGS001277 | PPM008887 | PSS004348 | PGP000244 | PE +/- DVT | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | 0.64659 | 0.63085 | 0.66233 | null | null | null | null | null | 67,425 | European |
PGS001279 | PPM008897 | PSS004018 | PGP000244 | Blood clot in the lung | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | 0.62416 | 0.60164 | 0.64668 | null | null | null | null | null | 67,349 | European |
PGS000995 | PPM007742 | PSS003993 | PGP000244 | Dentures | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | 0.72652 | 0.72179 | 0.73124 | null | null | null | null | null | 67,277 | European |
PGS000947 | PPM007563 | PSS003774 | PGP000244 | Mouth ulcers | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | 0.59736 | 0.59049 | 0.60422 | null | null | null | null | null | 67,277 | European |
PGS001166 | PPM008554 | PSS005115 | PGP000244 | Leg fat-free mass (L) | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 66,253 | European |
PGS001235 | PPM008688 | PSS005140 | PGP000244 | Arm pred. mass (R) | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 66,247 | European |
PGS003944 | PPM019039 | PSS011139 | PGP000502 | Eosinophil percentage | age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) | 37,890,495 | 10.1016/j.ajhg.2023.09.013 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 65,814 | European |
PGS002145 | PPM012007 | PSS009415 | PGP000263 | Headaches for 3+ months | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 3,905 | European |
PGS001218 | PPM008628 | PSS006940 | PGP000244 | Mean corpuscular haemoglobin concentration | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 65,635 | European |
PGS001134 | PPM008402 | PSS007270 | PGP000244 | Systolic BP (AR) | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 63,823 | European |
PGS000680 | PPM007329 | PSS007145 | PGP000244 | Cystatin C | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 64,468 | European |
PGS000672 | PPM007289 | PSS007100 | PGP000244 | Apolipoprotein B | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 64,166 | European |
PGS002105 | PPM011696 | PSS009388 | PGP000263 | Birth weight | sex, age, birth date, deprivation index, 16 PCs | 34,995,502 | 10.1016/j.ajhg.2021.11.008 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 11,255 | European |
PGS003494 | PPM017422 | PSS010903 | PGP000457 | Birth weight | sex, age, deprivation index, PC1-16 | null | 10.1101/2022.09.28.509988 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 11,297 | European |
PGS000318 | PPM000850 | PSS000409 | PGP000095 | All-cause mortality (age at death in females) | 10 genetic PCs | 32,758,451 | 10.1016/j.ajhg.2020.07.002 | null | null | null | null | 1.1 | 1.05 | 1.16 | null | null | null | null | null | null | null | null | null | null | null | null | null | 60,308 | European |
PGS000466 | PPM001151 | PSS000569 | PGP000118 | Squamous cell carcinoma | age, sex, batch PCs 1-4 | 32,991,828 | 10.1016/j.ajhg.2020.08.025 | 1.327 | 1.292 | 1.364 | null | null | null | null | null | 0.283 | null | null | 0.0138 | 0.57 | 0.562 | 0.578 | null | null | null | null | null | 60,018 | European |
PGS004336 | PPM020451 | PSS011364 | PGP000561 | Gamma glutamyltransferase (U/L) | null | 38,351,177 | 10.1038/s42003-024-05874-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 56,192 | European |
PGS004359 | PPM020474 | PSS011364 | PGP000561 | Lymphocyte percentage | null | 38,351,177 | 10.1038/s42003-024-05874-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 56,192 | European |
PGS004373 | PPM020488 | PSS011364 | PGP000561 | weight | null | 38,351,177 | 10.1038/s42003-024-05874-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 56,192 | European |
PGS004374 | PPM020489 | PSS011364 | PGP000561 | Body fat percentage | null | 38,351,177 | 10.1038/s42003-024-05874-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 56,192 | European |
PGS004405 | PPM020520 | PSS011364 | PGP000561 | Waist circumference | null | 38,351,177 | 10.1038/s42003-024-05874-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 56,192 | European |
PGS004414 | PPM020529 | PSS011364 | PGP000561 | Heel quantitative ultrasound index (QUI), direct entry | null | 38,351,177 | 10.1038/s42003-024-05874-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 56,192 | European |
PGS002623 | PPM014290 | PSS009865 | PGP000332 | Vitamin D | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 39,443 | European |
PGS002695 | PPM014656 | PSS009761 | PGP000332 | HDL Cholesterol | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 37,633 | European |
PGS000931 | PPM007486 | PSS003794 | PGP000244 | Blood clot or DVT diagnosed by doctor | age, sex, UKB array type, Genotype PCs | 35,324,888 | 10.1371/journal.pgen.1010105 | null | null | null | null | null | null | null | null | null | null | null | null | 0.62837 | 0.61546 | 0.64128 | null | null | null | null | null | 48,060 | European |
PGS004678 | PPM020863 | PSS011429 | PGP000595 | Total cholesterol | null | 38,622,117 | 10.1038/s41467-024-47357-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 5,153 | South Asian |
PGS004680 | PPM020865 | PSS011429 | PGP000595 | Total cholesterol | null | 38,622,117 | 10.1038/s41467-024-47357-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 5,153 | South Asian |
PGS004225 | PPM020215 | PSS011306 | PGP000526 | Type 2 diabetes | age, gender, SBP, DBP, FBG, TC, TG, HDLC, and diabetes family history | 37,432,247 | 10.3390/nu15092144 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 5,024 | East Asian |
PGS002561 | PPM014081 | PSS009813 | PGP000332 | Neuroticism | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 34,276 | European |
PGS002550 | PPM014070 | PSS009769 | PGP000332 | HbA1c | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 38,991 | European |
PGS003779 | PPM018586 | PSS011040 | PGP000489 | High-density lipoprotein cholesterol | null | 37,749,244 | 10.1038/s41588-023-01501-z | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 4,702 | South Asian |
PGS002716 | PPM014677 | PSS009845 | PGP000332 | Tanning | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 42,556 | European |
PGS004521 | PPM020636 | PSS011364 | PGP000561 | F41 (Other anxiety disorders) | null | 38,351,177 | 10.1038/s42003-024-05874-7 | 1.295715 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 56,192 | European |
PGS004696 | PPM020904 | PSS011448 | PGP000602 | Incident coronary heart disease | age, sex, 10 PCs | 38,380,516 | 10.1161/circgen.123.004272 | 1.65 | 1.59 | 1.71 | null | null | null | null | null | null | null | null | null | 0.774 | null | null | null | null | null | null | null | 52,702 | European |
PGS005014 | PPM022059 | PSS011824 | PGP000679 | Systolic blood pressure | score previously adjusted for age, sex, 20 PCs | 39,323,095 | 10.1016/j.xhgg.2024.100355 | null | null | null | null | null | null | null | null | 0.082 | 0.07 | 0.09 | null | null | null | null | null | null | null | null | null | 45,505 | European |
PGS005011 | PPM022148 | PSS011824 | PGP000679 | Systolic blood pressure | score previously adjusted for age, sex, 20 PCs | 39,323,095 | 10.1016/j.xhgg.2024.100355 | null | null | null | null | null | null | null | null | 0.16 | 0.15 | 0.17 | null | null | null | null | null | null | null | null | null | 45,505 | European |
PGS005006 | PPM022037 | PSS011823 | PGP000679 | Height | score previously adjusted for age, sex, 20 PCs | 39,323,095 | 10.1016/j.xhgg.2024.100355 | null | null | null | null | null | null | null | null | 0.291 | 0.28 | 0.3 | null | null | null | null | null | null | null | null | null | 45,413 | European |
PGS004175 | PPM020108 | PSS011296 | PGP000520 | Type 1 diabetes | year of birth, sex | 37,468,507 | 10.1038/s41598-023-37580-5 | null | null | null | null | null | null | null | null | null | null | null | null | 0.7 | null | null | null | null | null | null | null | 45,334 | European |
PGS004206 | PPM020139 | PSS011296 | PGP000520 | Direct bilirubin | year of birth, sex | 37,468,507 | 10.1038/s41598-023-37580-5 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 45,334 | European |
PGS002555 | PPM014075 | PSS009789 | PGP000332 | Hypothyroidism | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 43,505 | European |
PGS002592 | PPM014259 | PSS009741 | PGP000332 | Endocrine and diabetes diseases | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 43,505 | European |
PGS002591 | PPM014258 | PSS009737 | PGP000332 | Eczema | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 43,398 | European |
PGS002319 | PPM013182 | PSS009721 | PGP000332 | College education | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 42,914 | European |
PGS002711 | PPM014672 | PSS009825 | PGP000332 | Red Blood Cell Count | age, sex, age*sex, assessment center, genotyping array, 10 PCs | 35,393,596 | 10.1038/s41588-022-01036-9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 42,065 | European |
PGS004670 | PPM020855 | PSS011421 | PGP000595 | Total cholesterol | null | 38,622,117 | 10.1038/s41467-024-47357-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 4,302 | African American or Afro-Caribbean |
PGS004656 | PPM020841 | PSS011423 | PGP000595 | Log triglycerides | null | 38,622,117 | 10.1038/s41467-024-47357-7 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 4,300 | African American or Afro-Caribbean |
PGS003803 | PPM018610 | PSS011051 | PGP000489 | Log triglycerides | null | 37,749,244 | 10.1038/s41588-023-01501-z | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 4,300 | African American or Afro-Caribbean |
PGS003807 | PPM018614 | PSS011051 | PGP000489 | Log triglycerides | null | 37,749,244 | 10.1038/s41588-023-01501-z | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 4,300 | African American or Afro-Caribbean |
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PGS Catalog — Cleaned Polygenic Risk Score Metadata
Cleaned and normalized metadata from the PGS Catalog, the open database of published Polygenic Risk Scores (PRS).
This dataset is automatically built from the bulk FTP downloads provided by PGS Catalog
and processed through the just-prs cleanup pipeline.
Last updated: 2026-02-19
Files
All files are in the data/ directory in Apache Parquet format.
| File | Rows | Columns | Key columns |
|---|---|---|---|
scores.parquet |
5,251 | 12 | pgs_id, name, trait_reported, trait_efo, trait_efo_id, genome_build, n_variants, weight_type, ... (12 total) |
performance.parquet |
20,788 | 30 | ppm_id, pgs_id, pss_id, pgp_id, trait_reported, covariates, pmid, doi, ... (30 total) |
best_performance.parquet |
5,233 | 30 | pgs_id, ppm_id, pss_id, pgp_id, trait_reported, covariates, pmid, doi, ... (30 total) |
Cleanup Pipeline
The raw PGS Catalog CSVs undergo several transformations:
- Column renaming — verbose PGS column names (e.g.
Polygenic Score (PGS) ID) are mapped to shortsnake_caseequivalents (pgs_id). - Genome build normalization — 9 raw build variants (
hg19,hg37,hg38,NCBI36,hg18,NCBI35,GRCh37,GRCh38,NR) are mapped to canonical values:GRCh37,GRCh38,GRCh36, orNR. - Metric string parsing — performance metrics stored as strings like
"1.55 [1.52,1.58]"or"-0.7 (0.15)"are parsed into structured numeric columns (*_estimate,*_ci_lower,*_ci_upper,*_se) for OR, HR, Beta, AUROC, and C-index. - Performance flattening — performance metrics are joined with evaluation sample sets to include
sample size (
n_individuals) and ancestry (ancestry_broad). - Best performance selection —
best_performance.parquetcontains one row per PGS ID, selecting the evaluation with the largest sample size (with a preference for European-ancestry cohorts).
Table Descriptions
scores.parquet
One row per polygenic score in PGS Catalog. Key columns:
pgs_id— PGS Catalog identifier (e.g. PGS000001)name— score nametrait_reported/trait_efo— reported and mapped trait labelsgenome_build— normalized genome build (GRCh37, GRCh38, GRCh36, or NR)n_variants— number of variants in the scoring fileweight_type— type of variant weights (e.g. beta, OR, log(OR))ftp_link— direct FTP link to the scoring file
performance.parquet
One row per performance evaluation, with parsed numeric metrics:
ppm_id— performance metric identifierpgs_id— evaluated scoreor_estimate,hr_estimate,beta_estimate,auroc_estimate,cindex_estimate— parsed point estimates*_ci_lower,*_ci_upper,*_se— confidence intervals and standard errorsn_individuals,ancestry_broad— evaluation sample characteristics
best_performance.parquet
One row per PGS ID with the single best performance evaluation (largest sample, European-preferred).
Same columns as performance.parquet.
Source & License
- Source: PGS Catalog (EBI / NHGRI)
- License: CC BY 4.0
- Citation: Lambert, S.A. et al. The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation. Nature Genetics 53, 420–425 (2021). doi:10.1038/s41588-021-00783-5
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