Pubmed Text
Collection
Collection of pubmed 2024 papers. • 11 items • Updated
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20859921 | [Changes in the functional magnetic resonance imaging of the sensorimotor cortex in traumatic brain injury after intensive rehabilitation]. | To evaluate the potential reorganization of the sensorimotor cortex in a patient with traumatic brain injury after an intensive motor rehabilitation. |
20859920 | [Differential contribution of preoperatory studies to diagnosis in temporal lobe epilepsy surgery]. | It is necessary to know the degree of concordance of preoperative studies in temporal lobe epilepsy (TLE). AIM. To analyze the relative importance of different preoperative tests (vEEG, EEG, SPECT and MRI), the degree of agreement between them, and to develop a Bayesian probability model for diagnosis. |
20859922 | [Neuropsychological performance in cocaine addiction: a critical review]. | Chronic use of cocaine has been associated with a wide range of neuropsychological deficits affecting attention, memory, learning and executive functions. However, it has not been found a unique profile of impairment associated with cocaine addiction. |
20859923 | Sensorimotor integration: basic concepts, abnormalities related to movement disorders and sensorimotor training-induced cortical reorganization. | Sensorimotor integration is defined as the capability of the central nervous system to integrate different sources of stimuli, and parallelly, to transform such inputs in motor actions. |
20859924 | [Neurology in Byzantine medicine. An analysis of Alexander of Tralles' Medici libri duodecim]. | Byzantium continued Greek and Roman habit of pilation, and so, preserved medical knowledge. In addition, assimilating the influence of Monastic and Arabic medicine, Byzantine physicians transmitted original contributions including references to neurological diseases. Alexander of Tralles was one of major exponents of B... |
20859928 | Semiochemicals of the common bed bug, Cimex lectularius L. (Hemiptera: Cimicidae), and their potential for use in monitoring and control. | The recent resurgence of mon bed bug, Cimex lectularius L., has driven an increase in research into the biology and behaviour of this pest. Current control is reliant on the application of insecticides, but, owing to the development of insecticide resistance, there is a need for new tools and techniques. Semiochemicals... |
20859929 | Differential scanning calorimetry thermal properties and oxidative stability indices of microwave heated extra virgin olive oils. | The use of differential scanning calorimetry (DSC) for assessing the deterioration effect of microwave heating on vegetable oils, and on olive oils in particular, has been partially explored in literature. The aim of this work was to evaluate the potential of DSC to discriminate among microwaved extra virgin olive oils... |
20859932 | Group psychoeducation for long-term offender patients with schizophrenia: an exploratory randomised controlled trial. | Psychoeducation is monly provided in forensic settings, but its effectiveness among long-term offender patients with schizophrenia has not yet been established in randomised controlled trials (RCTs). |
20859930 | Transient expression of antibodies in suspension plant cell suspension cultures is enhanced when co-transformed with the tomato bushy stunt virus p19 viral suppressor of gene silencing. | Two distinct transient expression approaches pared with assess the impact of the viral suppressor p19 on a binant protein production performed in Nicotiana benthamiana suspension culture. A parental N. benthamiana cell line was transiently transformed with either an Agrobacterium containing a gene construct for a murin... |
20859931 | Achieving high mass-throughput of therapeutic proteins through parvovirus retentive filters. | Parvovirus retentive filters that assure removal of viruses and virus-like particles during the production of therapeutic proteins significantly contribute to total manufacturing costs. Operational approaches that can increase throughput and reduce filtration area would result in a significant cost savings. bination of... |
20859934 | Experimental measurement of the regulation of anger and aggression in women with anorexia nervosa. | Anorexia nervosa (AN) is associated with difficulties in emotion regulation and this study aimed to examine emotion regulation experimentally in this pared to healthy controls (HCs). Sixty-six women took part: 22 with AN and 44 HCs. Both pleted the Rosenzweig Picture Frustration Study in which participants' responses t... |
20859941 | Metal-assisted chemical etching of silicon: a review. | This article presents an overview of the essential aspects in the fabrication of silicon and some silicon/germanium nanostructures by metal-assisted chemical etching. First, the basic process and mechanism of metal-assisted chemical etching is introduced. Then, the various influences of the noble metal, the etchant, te... |
20859933 | Bionanoconjugate-based composites for decontamination of nerve agents. | We have developed posites that rapidly and effectively detoxify simulants of V- and G-type chemical warfare nerve agents. The approach was based on the efficient immobilization of organophosphorus hydrolase onto carbon nanotubes to form active and stable conjugates that were easily entrapped mercially available paints.... |
20859948 | Ultrabright fluorescent mesoporous silica nanoparticles. | The first successful approach to synthesizing ultrabright fluorescent mesoporous silica nanoparticles is reported. Fluorescent dye is physically entrapped inside nanochannels of a silica matrix created during templated sol-gel self-assembly. The problem of dye leakage from open channels is solved by incorporation of hy... |
20859952 | Dispersive liquid-liquid microextraction combined with nonaqueous capillary electrophoresis for the determination of fluoroquinolone antibiotics in waters. | Dispersive liquid-liquid microextraction (DLLME) bined for the first time with NACE-UV for the selective determination of eight fluoroquinolone antibiotics (lomefloxacin, levofloxacin, marbofloxacin, ciprofloxacin, sarafloxacin, enrofloxacin, danofloxacin and difloxacin) in mineral and run-off waters. Field-enhanced sa... |
20859951 | Alpha-1 antitrypsin variants in plasma from HIV-infected patients revealed by proteomic and glycoproteomic analysis. | Novel tools are necessary to explore proteins related to human immunodeficiency virus (HIV) infection. In this work, proteomic and glycoproteomic technology were employed to examine plasma samples from HIV-positive patients. parative proteome analysis of normal and HIV-positive plasma samples, 19 differentially express... |
20859953 | Chromatographic determination of solubilities in superheated water. | Superheated water (SHW) is an effective solvent for the extraction of a variety of environmental pollutants, but knowledge of the solubilities in water at elevated temperatures necessary to maximise the efficiency of the process is often lacking. Ambient temperature aqueous solubilities have been measured by reverse-ph... |
20859954 | Simultaneous capillary electrophoretic analysis of inorganic anions and cations in post-blast extracts of acid-aluminum mixtures. | Bursts resulting from the chemical reaction between hydrochloric or nitric acid with aluminum foils are very mitted by the young delinquency in western countries because of its easiness of achievement. A fast, simple, selective, and cost-effective method allowing the simultaneous detection of chloride and nitrate anion... |
20859955 | A simplified method for the determination of total homocysteine in plasma by electrospray tandem mass spectrometry. | Hyperhomocysteinemia is a risk factor for different diseases. Several methods have been developed to analyze homocysteine and the immunometric ones, although expensive, they are in widespread use. A rapid LC-MS/MS method for homocysteine assay has been developed for the application of large clinical chemistry routines.... |
20859956 | Proteomic identification of microRNA-122a target proteins in hepatocellular carcinoma. | MicroRNA-122a (miR-122a) is a liver-specific miRNA that is frequently downregulated in hepatocellular carcinoma (HCC). The exact functional role of miR-122a and its target in HCC remain largely unknown. We developed a lentiviral vector for the expression of pre-miR-122a (Lenti-miR-122a). Lenti-miR-122a inhibited HCC ce... |
20859957 | Development of a new method using HILIC-tandem mass spectrometry for the characterization of O-sialoglycopeptides from proteolytically digested caseinomacropeptide. | This work addresses the optimization of HILIC (hydrophilic interaction liquid chromatography)-ESI-MS(n) conditions for prehensive characterization of O-glycopeptides from proteolytically digested caseinomacropeptide. O-Glycopeptides were satisfactorily analysed on a zwitterionic HILIC column based on their glycan struc... |
20859958 | Achievements and perspectives of top-down proteomics. | Over the last years, top-down (TD) MS has gained a remarkable space in proteomics, rapidly trespassing the limit between a promising approach and a solid, established technique. Several research groups worldwide have implemented TD analysis in their routine work on proteomics, deriving structural information on protein... |
20859959 | High-efficiency nano- and micro-HPLC--high-resolution Orbitrap-MS platform for top-down proteomics. | In terms of resolution, mass accuracy, and sensitivity, the Orbitrap represents one of the most potent mass analyzers available today. We here elucidate the potential of interfacing Orbitrap-MS to ion-pair RP HPLC for intact protein analysis. Using gradients of ACN and monolithic columns of 1.0 and 0.10 mm id, peak cap... |
20859961 | Syntheses and photophysical properties of N-pyridylimidazol-2-ylidene tetracyanoruthenates(II) and photochromic studies of their dithienylethene-containing derivatives. | A series of tetracyanoruthenate(II) with chelating pyridyl N-heterocyclic carbene ligands (NHC-py) was synthesized and characterized. Their photophysical and electrochemical properties as well as the photochromic behavior of their plexes were studied. Photocyclization was found to take place upon irradiation into the m... |
20859960 | The crystal structure of non-modified and bipyridine-modified PNA duplexes. | Peptide nucleic acid (PNA) is a synthetic analogue of DNA monly has an N-aminoethyl glycine backbone. The crystal structures of two PNA duplexes, one containing eight standard nucleobase pairs (GGCATGCC)(2), and the other containing the same nucleobase pairs and a central pair of bipyridine ligands, have been solved wi... |
20859962 | Solution structure, mechanism of replication, and optimization of an unnatural base pair. | As part of an ongoing effort to expand the genetic alphabet for in vitro and eventual in vivo applications, we have synthesized a wide variety of predominantly hydrophobic unnatural base pairs and evaluated their replication in DNA. Collectively, the results have led us to propose that these base pairs, which lack stab... |
20859963 | The total synthesis of (±)-fumimycin. | The antibiotic agent fumimycin has been synthesized for the first time. This natural product was found to inhibit the bacterial peptide deformylase and may represent a lead structure to a class of novel antibacterials. Our synthetic strategy towards fumimycin involved the following steps: Dakin oxidation of an aldehyde... |
20859964 | High-yielding synthesis of the anti-influenza neuraminidase inhibitor (-)-oseltamivir by two "one-pot" sequences. | The efficient asymmetric total synthesis of (-)-oseltamivir, an antiviral reagent, has been plished by using two "one-pot" reaction sequences, with excellent overall yield (60 %) and only one required purification by column chromatography. The first one-pot reaction sequence consists of a diphenylprolinol silyl ether m... |
20859965 | A facile route to metal nitride clusterfullerenes by using guanidinium salts: a selective organic solid as the nitrogen source. | Using guanidinium salts 1 and 2 as the new nitrogen sources, metal nitride clusterfullerenes (NCFs) based on a variety of metals (Dy, Sc, Y, Gd, Lu, and mixed metals Sc/Dy, Sc/Gd, Sc/Lu, and Lu/Ce) have been synthesized based on a new "selective organic solid" (SOS) route. The synthesis of Dy-NCFs by using Dy/1 was stu... |
20859966 | A general synthesis of alkenyl-substituted benzofurans, indoles, and isoquinolones by cascade palladium-catalyzed heterocyclization/oxidative Heck coupling. | Structurally diverse C3-alkenylbenzofurans, C3-alkenylindoles, and C4-alkenylisoquinolones are efficiently prepared by using consecutive Sonogashira and cascade Pd-catalyzed heterocyclization/oxidative Heck couplings from readily available ortho-iodosubstituted phenol, aniline, and benzamide substrates, alkynes, and fu... |
20859969 | Molecular gallium arsenide phosphide clusters prepared from AsP(3), P(4), and [{GaC(SiMe(3))(3)}(4)]. | Treatment of AsP(3) with 0.75 equivalents of [{GaC(SiMe(3))(3)}(4)] resulted in selective insertion of three equivalents of {GaC(SiMe(3))(3)} into the three As--P bonds to give [As{GaC(SiMe(3))(3)}(3)P(3)] (1-As) with an intact cyclo-P(3) ring. This pound has been characterized by NMR bustion analysis, single-crystal X... |
20859968 | Cyclization of zincated α-N-homoallylamino nitriles: a new entry to enantiopure 2,3-methanopyrrolidines. | Stereoselective cyclization of zincated α-N-homoallylamino nitriles has been developed. Following treatment with lithium diisopropylamide (LDA) and transmetalation with zinc bromide, α-N-(1-phenylethyl)-N-homoallylamino nitriles lead to 2,3-methanopyrrolidines in moderate to good yields (up to 66 %) and excellent selec... |
20859967 | Glyco-pseudopolyrotaxanes: carbohydrate wheels threaded on a polymer string and their inhibition of bacterial adhesion. | We report posed of cucurbit[6]uril-based mannose wheels (ManCB[6]) threaded on polyviologen (PV), which not only effectively induce bacterial aggregation, but also exhibit high inhibitory activity against bacterial binding to host cells. Three glyco-pseudopolyrotaxanes (1-3), which have 10, 5, and 3 ManCB[6] wheels, re... |
20859972 | A continuous flow process using a sequence of microreactors with in-line IR analysis for the preparation of N,N-diethyl-4-(3-fluorophenylpiperidin-4-ylidenemethyl)benzamide as a potent and highly selective δ-opioid receptor agonist. | This article describes the design, optimisation and development of a continuous flow synthesis of N,N-diethyl-4-(3-fluorophenylpiperidin-4-ylidenemethyl)benzamide, a potent δ-opioid receptor agonist developed by AstraZeneca. The process employs a sequence of flow-based microreactors, with integrated purification employ... |
20859975 | Factors determining the selection of organic reactions by medicinal chemists and the use of these reactions in arrays (small focused libraries). | Synthetic organic reactions are a fundamental enabler of small-molecule drug discovery, and the vast majority of medicinal chemists are initially trained--either at universities or within industry--as synthetic organic chemists. The sheer breadth of synthetic methodology available to the medicinal chemist represents an... |
20859985 | Templated chemistry for sequence-specific fluorogenic detection of duplex DNA. | We describe the development of templated fluorogenic chemistry for detection of specific sequences of duplex DNA in solution. In this approach, two modified homopyrimidine oligodeoxynucleotide probes are designed to bind by triple-helix formation at adjacent positions on a specific purine-rich target sequence of duplex... |
20859987 | Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates. | A new family of dual binding site acetylcholinesterase (AChE) inhibitors has been designed, synthesized, and tested for their ability to inhibit AChE, butyrylcholinesterase (BChE), AChE-induced and self-induced β-amyloid (Aβ) aggregation and β-secretase (BACE-1), and to cross the blood-brain barrier. The new heterodime... |
20859988 | The effect of germination on the phytase activity, phytate and total phosphorus contents of some Nigerian-grown grain legumes. | Grain legumes are under-exploited as possible sources of phytase for the poultry industry. The current study was conducted to assess the effect of germination on phytase activities, phytate and total phosphorus content in samples of Nigerian-grown grain legumes. The legumes screened were African yambean (AYB, Sphenosty... |
20859991 | Transcriptional coactivators p300 and CBP stimulate estrogen receptor-beta signaling and regulate cellular events in prostate cancer. | Steroid receptor coactivators p300 and CBP are highly expressed in advanced prostate cancer. They potentiate activation of androgen receptor by androgens and anti-androgens. In the present study, we have addressed the question whether these coactivators enhance activity of estrogen receptor-beta (ER-β), which is variab... |
20859993 | Influence of brain tumors on the MR spectra of healthy brain tissue. | The neurochemical environment of nontumorous white matter tissue was investigated in 135 single voxel spectra of "healthy" white matter regions of 43 tumor patients and 129 spectra of 52 healthy subjects. Spectra were acquired with short TE and TR values. With the data of tumor patients, it was examined whether differe... |
20859992 | Receptors for luteinizing hormone-releasing hormone (LHRH) in benign prostatic hyperplasia (BPH) as potential molecular targets for therapy with LHRH antagonist cetrorelix. | The majority of men will develop symptoms of benign prostatic hyperplasia (BPH) after 70 years of age. Various studies indicate that antagonists of LHRH, such as cetrorelix, exert direct inhibitory effects on BPH mediated by specific LHRH receptors. Our aim was to investigate the mRNA for LHRH and LHRH receptors and th... |
20859994 | Immobilized contrast-enhanced MRI: Gadolinium-based long-term MR contrast enhancement of the vein graft vessel wall. | An implantable MR contrast agent that can be covalently immobilized on tissue during surgery has been developed. The rationale is that a durable increase in tissue contrast using an implantable contrast agent can enhance postsurgical tissue differentiation using MRI. For small-vessel (e.g., vein graft) MRI, the direct ... |
20859989 | Evaluation of a guided internet self-treatment programme for bulimia nervosa in several European countries. | The purposes of this study were to evaluate the use of an online guided self-treatment programme for bulimia nervosa (BN) and to determine predictors of e. Data were collected in four European countries where the programme was simultaneously used. |
20859995 | An analytical description of balanced steady-state free precession with finite radio-frequency excitation. | Conceptually, the only flaw in the standard steady-state free precession theory is the assumption of quasi-instantaneous radio-frequency pulses, and 10-20% signal deviations from theory are observed mon balanced steady-state free precession protocols. This discrepancy in the steady-state signal can be resolved by a sim... |
20859996 | Post-processing correction of magnetization transfer effects in FENSI perfusion MRI data. | Magnetization transfer effects induced by repetitive saturation pulses employed in flow enhancement of signal intensity imaging sequences currently prevent quantitative, in vivo, cerebral perfusion studies. This study investigates the magnitude of these effects and introduces a post-processing correction protocol. The ... |
20859990 | Enhanced cognitive behavioural therapy for an adolescent with purging disorder: a case report. | To present a case report detailing the use of an enhanced form of cognitive behaviour therapy (CBT). The treatment was provided to an adolescent with an eating disorder not otherwise specified (EDNOS) diagnosis, and included a focus on the additional maintaining mechanisms of mood intolerance and interpersonal problems... |
20859997 | Longitudinal MR assessment of hypoxic ischemic injury in the immature rat brain. | Extremely preterm monly show brain injury with long-term structural and functional consequences. Three-day-old (P3) rat pups share some similarities in terms of cerebral development with the very preterm infant (born at 24-28 weeks of gestation). The aim of this study was to assess longitudinally the cerebral structura... |
20859998 | Compressed sensing for chemical shift-based water-fat separation. | Multi echo chemical shift-based water-fat separation methods allow for uniform fat suppression in the presence of main field inhomogeneities. However, these methods require additional scan time for chemical shift encoding. This work presents a method for water-fat separation from undersampled data (CS-WF), pressed sens... |
20859999 | Prognostic value of heparanase expression and cellular localization in oral cancer. | Metastases formation depends on the ability of tumor cells to invade basement membranes in a process involving enzymes capable of degrading extracellular ponents. |
20860000 | Mapping of redox status in a brain-disease mouse model by three-dimensional EPR imaging. | Electron paramagnetic resonance imaging using nitroxides is a powerful method for visualizing the redox status modulated by oxidative stress in vivo. Typically, however, data acquisition times have been too slow to obtain a sufficient number of projections for three-dimensional images, when using continuous wave-electr... |
20860003 | Highly accelerated contrast-enhanced MR angiography: improved reconstruction accuracy and reduced noise amplification with complex subtraction. | Contrast-enhanced magnetic resonance angiography is routinely performed using parallel imaging to best capture the first pass of contrast material through the target vasculature, followed by digital subtraction to suppress the appearance of unwanted signal from background tissue. Both processes, however, amplify noise ... |
20860001 | Dynamic contrast-enhanced MRI of neuroendocrine hepatic metastases: A feasibility study using a dual-input two-compartment model. | Neuroendocrine hepatic metastases exhibit various contrast uptake enhancement patterns in dynamic contrast-enhanced MRI. Using a dual-input partment distributed parameter model, we analyzed the dynamic contrast-enhanced MRI datasets of seven patient study cases with the aim to relate the tumor contrast uptake patterns ... |
20860002 | Brain MR perfusion-weighted imaging with alternate ascending/descending directional navigation. | In this study, a new arterial spin labeling technique that requires no separate spin preparation pulse was developed. Sequential two-dimensional slices were acquired in ascending and descending orders by turns using balanced steady state free precession for pair-wise subtraction. Simulation studies showed this new tech... |
20860004 | Assessment of multiexponential diffusion features as MRI cancer therapy response metrics. | The aim of this study was to empirically test the effect of chemotherapy-induced tissue changes in a glioma model as measured by several diffusion indices calculated from nonmonoexponential formalisms over a wide range of b-values. We pared these results to the conventional two-point apparent diffusion coefficient calc... |
20860006 | Dual-echo Dixon imaging with flexible choice of echo times. | In this work, a new two-point method for water-fat imaging is described and explored. It generalizes existing two-point methods by eliminating some of the restrictions that these methods impose on the choice of echo times. Thus, the new two-point method promises to provide more freedom in the selection of protocol para... |
20860008 | A new method to provide a fresh frozen prostate slice suitable for gene expression study and MR spectroscopy. | Fresh frozen tissue from radical prostatectomy specimens is highly valuable material for research on gene expression and cellular metabolites. The purpose of this study was to develop a standardized method to provide a representative high quality research sample from radical prostatectomy specimens without interfering ... |
20860007 | In vivo observation of intracellular oximetry in perfluorocarbon-labeled glioma cells and chemotherapeutic response in the CNS using fluorine-19 MRI. | Preclinical development of therapeutic agents against cancer could greatly benefit from noninvasive markers of tumor killing. Potentially, the intracellular partial pressure of oxygen (pO(2) ) can be used as an early marker of antitumor efficacy. Here, the feasibility of measuring intracellular pO(2) of central nervous... |
20860009 | Prostate cancer risk alleles significantly improve disease detection and are associated with aggressive features in patients with a "normal" prostate specific antigen and digital rectal examination. | Several reports suggest that bination of risk alleles may be associated with prostate cancer (CaP) risk and tumor features. However, their ability to detect CaP and tumor characteristics in patients with a "normal" PSA (<4 ng/ml) and non-suspicious digital rectal examination (DRE) remains to be determined. |
20860010 | Glycation sites in neoglycoglycoconjugates from the terminal monosaccharide antigen of the O-PS of Vibrio cholerae O1, serotype Ogawa, and BSA revealed by matrix-assisted laser desorption-ionization tandem mass spectrometry. | We present the MALDI-TOF/TOF-MS analyses of various hapten-bovine serum albumin (BSA) neoglycoconjugates obtained by squaric acid chemistry coupling of the spacer-equipped, terminal monosaccharide of the O-specific polysaccharide of Vibrio cholerae O1, serotype Ogawa, to BSA. These analyses allowed not only to calculat... |
20860011 | Truncated bFGF-mediated cationic liposomal paclitaxel for tumor-targeted drug delivery: improved pharmacokinetics and biodistribution in tumor-bearing mice. | Fibroblast growth factor receptors, overexpressed on the surface of a variety of tumor cells and on tumor neovasculature, are potential targets for tumor- and vascular-targeting therapy. The purpose of our present study was pare the pharmacokinetics and tissue distribution of a novel truncated basic fibroblast growth f... |
20860013 | Compositional studies of human RPE lipofuscin. | Age-related macular degeneration (AMD) is an ocular disease that causes visual loss and legal blindness in the elderly population. The etiology of AMD plex and may include genetic predispositions, accumulation of lipofuscin and drusen, local inflammation and neovascularization. The accumulation of lipofuscin has been s... |
20860012 | On variability in test results of current in vitro dissolution tests. | An analysis of theoretical cumulative mass dissolved-time profile curves represented by Weibull distributions serves to illustrate a dependency of variability in test results of current in vitro dissolution tests, on slope of a profile curve and amount of a cumulative time-shift, at any given point of a dissolution pro... |
20860014 | Exploring the mechanisms of intravesical electrical stimulation in the in vitro rat whole bladder after treatment with atropine, α,β-methylATP and tetrodotoxin. | In a previous study, we showed that the working mechanism of intravesical electrical stimulation (IVES) is probably mainly nerve mediated. But even after bladder decentralization, IVES can induce detrusor contraction. This study explores the effect of IVES in decentralized bladders and the importance of receptors in th... |
20860015 | Clinical relevance of urethral stents (Urospiral 2™) placement in patients with prostatic obstacle and concomitant high-risk surgical status or neurological diseases: a feasibility and safety study. | To review the indications and to assess the functional es after placement of a new temporary urethral stent (TUS) in men with lower urinary tract dysfunction. |
20860017 | Exercise improves bladder function in diabetic mice. | We determined the effect of exercise on bladder dysfunction and voiding frequency in db/db mice. |
20860016 | Intravesical immune suppression by liposomal tacrolimus in cyclophosphamide-induced inflammatory cystitis. | Potent immunosuppressive effect of tacrolimus has encouraged its topical application for achieving local anti-inflammatory effect. However, its poor aqueous solubility presents challenges in formulating patible instillations to justify the investigation of liposomes as vehicle for tacrolimus. |
20860018 | Type and severity of new-onset urinary incontinence in middle-aged women: the Hordaland Women's Cohort. | To determine the natural history of new-onset urinary incontinence by type and severity in middle-aged women. |
20860019 | Body mass index and blood pressure changes over the course of treatment of pediatric acute lymphoblastic leukemia. | Obesity and hypertension are reported among survivors of pediatric acute lymphoblastic leukemia (ALL). However, little is known about the trajectory of body mass index (BMI) and blood pressure over the course of ALL therapy. |
20860020 | Patient satisfaction with the benefits of overactive bladder treatment: exploration of influencing factors and development of a satisfaction assessment instrument. | Patient-reported e (PRO) instruments are useful for assessing treatment success in patients with overactive bladder (OAB). PROs such as the OAB Questionnaire (OAB-q) and Patient Perception of Bladder Condition (PPBC) focus more on OAB symptoms than satisfaction. We describe the development of the Patient Satisfaction w... |
20860022 | The biosynthesis of branched dialkylpyrazines in myxobacteria. | The biosynthesis of the volatiles 2,5- and 2,6-diisopropylpyrazine (2 and 3, resp.) released by the myxobacteria Nannocystis exedens subsp. cinnabarina (Na c29) and Chondromyces crocatus (strains Cm c2 and Cm c5) was studied. Isotopically labeled precursors and proposed pathway intermediates were fed to agar plate cult... |
20860023 | 2-azapurine nucleosides: synthesis, properties, and base pairing of oligonucleotides. | This review deals with 2-azapurine (imidazo[4,5-d] [1,2,3]triazine) nucleosides and closely related analogs. Different routes are described to yield the desired pounds, including a sequence of ring-opening and ring-closure reactions performed on purine nucleosides or direct glycosylation of a 2-azapurine nucleobase wit... |
20860024 | An alternative standard for Trolox-equivalent antioxidant-capacity estimation based on thiol antioxidants. Comparative 2,2'-azinobis[3-ethylbenzothiazoline-6-sulfonic acid] decolorization and rotational viscometry study regarding hyaluronan degradation. | Comparison of the effectiveness of antioxidant activity of three pounds, D-penicillamine, reduced L-glutathione, and 1,4-dithioerythritol, expressed as a radical-scavenging capacity based on the two independent methods, namely a decolorization 2,2'-azinobis[3-ethylbenzothiazoline-6-sulfonic acid] assay and a rotational... |
20860026 | Volatile methyl esters of medium chain length from the bacterium Chitinophaga Fx7914. | The analysis of the volatiles released by the novel bacterial isolate Chitinophaga Fx7914 revealed the presence of ca. pounds including different methyl esters. These prise monomethyl- and dimethyl-branched, saturated, and unsaturated fatty acid methyl esters that have not been described as bacterial volatiles before. ... |
20860027 | Early-season headspace volatiles from apple and their effect on the apple blossom weevil Anthonomus pomorum. | Apple volatiles emitted at early phenological stages are little investigated, although they may influence behavior of early-season pests. The apple blossom weevil Anthonomus pomorum is a herbivore pest of orchards in Europe. It colonizes apple trees in early season and oviposits into developing flower buds, often leadi... |
20860028 | A survey of phytotoxic microbial and plant metabolites as potential natural products for pest management. | Phytotoxic microbial metabolites produced by certain phytopathogenic fungi and bacteria, and a group of phytotoxic plant metabolites including Amaryllidacea alkaloids and some derivatives of pounds were evaluated for algicide, bactericide, insecticide, fungicide, and herbicide activities in order to discover pounds for... |
20860030 | Bioactive triterpenoids from Kadsura heteroclita. | A phytochemical study of Kadsura heteroclita led to the isolation of eight triterpenoids, including two pounds, named kadheterilactone A (1) and kadheterilactone B (2), as well as six pounds, longipedlactone H (3), longipedlactone A (4), longipedlactone F (5), kadsuranic acid A (6), nigranoic acid (7), and schisandroni... |
20860029 | Phytochemical analysis and in vitro free-radical-scavenging activities of the essential oils from leaf and fruit of Melaleuca leucadendra L. | The phytochemical profile of Melaleuca leucadendra L. leaf and fruit oils from Cuba was investigated by GC and GC/MS. Forty-one and sixty-four pounds were identified and quantified, accounting for 99.2 and 99.5% of the leaf-oil and fruit-oil position, respectively. The ponents were 1,8-cineol (43.0%), viridiflorol (24.... |
20860032 | Anti-tumor-initiating effects of spiro-biflavonoids from Abies sachalinensis. | Cancer chemoprevention, the prevention of cancer by ingestion of chemical agents that reduce the risk of carcinogenesis, is one of the potent ways to reduce morbidity and mortality. We have been searching for cancer chemopreventive agents from the leaves and barks of coniferous trees that have been treated as waste in ... |
20860031 | Regulation of the 5-HT3A receptor-mediated current by alkyl 4-hydroxybenzoates isolated from the seeds of Nelumbo nucifera. | Four known alkyl 4-hydroxybenzoates, i.e., methyl 4-hydroxybenzoate (1), ethyl 4-hydroxybenzoate (2), propyl 4-hydroxybenzoate (3), and butyl 4-hydroxybenzoate (4), were isolated from the seeds of Nelumbo nucifera Gaertner (Nymphaeaceae) for the first time. The structures of the isolates were identified by 1D- and 2D-N... |
20860033 | Volatile composition screening of Salix spp. nectar honey: benzenecarboxylic acids, norisoprenoids, terpenes, and others. | Salix spp. nectar honey volatiles of Croatian origin were analyzed by headspace solid-phase microextraction (HS-SPME) and ultrasonic solvent extraction (USE), followed by gas chromatography and mass spectrometry (GC, GC/MS). Isolated volatiles were found in the honey headspace and extracts with almost exclusive distrib... |
20860036 | Protracted postpartum urinary retention: the importance of early diagnosis and timely intervention. | To evaluate the prevalence and obstetric risk factors of protracted postpartum urinary retention, beyond the third postpartum day. |
20860038 | Phase 1 trial and pharmacokinetic study of the farnesyl transferase inhibitor tipifarnib in children and adolescents with refractory leukemias: a report from the Children's Oncology Group. | The objectives of this trial were to define the toxicity profile, dose, pharmacokinetics, and pharmacodynamics of the farnesyl transferase (FTase) inhibitor, tipifarnib, in children and adolescents with hematological malignancies. |
20860039 | The quinoxaline anti-tumor agent (R+)XK469 inhibits neuroblastoma tumor growth. | The quinoxaline anti-tumor agent (R+)XK469 mediates its effects by topoisomerase IIB inhibition. This report describes a 14-year old with relapsed neuroblastoma who experienced disease stabilization for 14 months while receiving (R+)XK469 monotherapy. Due to this favorable response, laboratory studies were undertaken t... |
20860040 | Minor anomalies in children with hematological malignancies. | Despite the presence of reports on correlation between major congenital defects and cancer, very few studies have investigated the frequency of minor anomalies in childhood malignancy. The aim of this study was to determine the prevalence of minor anomalies in children with hematological malignancy. |
20860041 | Role of neoadjuvant chemotherapy in congenital intracranial haemangiopericytoma. | Infantile haemangiopericytoma of the CNS is a rare entity. We report the first case of a congenital haemangiopericytoma successfully treated by preoperative chemotherapy. The patient presented shortly after birth with the diagnosis of a haemangiopericytoma. As neurosurgery was too risky due to size, location and age of... |
20860042 | Sequential acquisition of IgH and TCR rearrangements during the preleukemic phase of acute lymphoblastic leukemia in an adolescent patient. | Acute lymphoblastic leukemia (ALL) can be preceded by a prodromal phase of bone marrow failure. In serial trephine biopsies in a girl with acquired bone marrow hypoplasia, we have identified a monoclonal B-cell precursor population characterized by a clone-specific IgH-FR3 gene rearrangement. Progression to ALL more th... |
20860043 | Malignant insulinoma in a child. | Insulinomas are rare tumors with an estimated incidence of one per 250,000 person-years. Most insulinomas are benign with less than 10% demonstrating malignant behavior, the vast majority of which occur in adults. A systemic review of the literature revealed only nine cases of malignant insulinomas occurring in childre... |
20860044 | Effect of cup inclination angle during microseparation and rim loading on the wear of BIOLOX® delta ceramic-on-ceramic total hip replacement. | Ceramic-on-ceramic (CoC) bearings in total hip replacements (THRs) have shown low wear volumes under standard gait in hip simulator studies. However, clinical reports have indicated variations in wear rates and formation of stripe-like wear area on the ceramic femoral heads. The aim of this study was to investigate the... |
20860047 | Bioactive bone cement with a low content of titania particles without postsilanization: effect of filler content on osteoconductivity, mechanical properties, and handling characteristics. | In this study, we developed three types of polymethylmethacrylate posite cement with low contents of nonsilanized titania particles (5, 10, and 20 wt % TiO(2), respectively: designated T5, T10, and T20). The osteoconductivity, mechanical properties, and handling characteristics of these cements pared with those mercial... |
20860046 | Effects of immersion time and frequency of water exchange on durability of etch-and-rinse adhesive. | This study evaluated the immediate and long-term bond strength to dentin (microtensile bond strength, μTBS) and silver nitrate uptake (SNU) of a three- and two-step etch-and-rinse adhesive under different water immersion times and frequency of water exchange. The adhesives posite resin were applied according to the man... |
20860045 | Characterization of hydroxyapatite-perovskite (CaTiO3) composites: phase evaluation and cellular response. | In this study, an attempt was made to develop an understanding of the densification behavior, phase stability, and patibility property of HA-CaTiO(3) posite. posites with varying CaTiO(3) (40-80 wt %) content were sintered at temperatures ranging from 1200°C to 1500°C for 3-5 hr to establish optimum processing paramete... |
20860048 | Endoscopic monitoring of infliximab therapy in Crohn's disease. | So far, infliximab (IFX) therapy for the treatment of Crohn's disease (CD) has generally been guided by clinical symptoms. Data on treatment response as ascertained by endoscopy in IFX therapy are scarce. The aims of this study were to measure the endoscopic response rate during IFX induction and maintenance therapy in... |
20860052 | Racial and ethnic disparities in work-related injuries and socio-economic resources among nursing assistants employed in US nursing homes. | We aimed to estimate the proportion of nursing assistants (NAs) in the US with work-related injuries and insufficient socio-economic resources by race/ethnicity. |
20860053 | Improving the quality of industry and occupation data at a central cancer registry. | Central cancer registries are required to collect industry and occupation (I/O) information when available, but the data reported are often plete. |
20860054 | Confounders and confusion: Dealing with cancer cases of occupational origin. | The recognition of occupational cancers is often hampered by confusion between the individual determinants of the disease and effects at the group level. |
20860055 | Case-control study of male germ cell tumors nested in a cohort of car-manufacturing workers: Findings from the occupational history. | To examine whether the previously observed excess risk of male germ cell cancer in a cohort of car-manufacturing workers can be attributed to occupational activities inside and/or outside the car industry. |
20860057 | Imaging modalities to assess structural birth defects in mutant mouse models. | Assessment of structural birth defects (SBDs) in animal models usually entails conducting detailed necropsy for anatomical defects followed by histological analysis for tissue defects. Recent advances in new imaging technologies have provided the means for rapid phenotyping of SBDs, such as using ultra-high frequency u... |
20860056 | Cryopreservation of mammalian embryos: Advancement of putting life on hold. | Rodent transgenesis and human-assisted reproductive programs involve multistep handling of preimplantation embryos. The efficacy of production and quality of results from conventionally scheduled programs are limited by temporal constraints other than the quality and quantities of embryos per se. The emergence of vitri... |
20860050 | Nanotechnology and HIV: potential applications for treatment and prevention. | HIV/AIDS is a global pandemic and is the leading infectious cause of death among adults. Although antiretroviral (ARV) therapy has dramatically improved the quality of life and increased the life expectancy of those infected with HIV, life-long suppressive treatment is required and a cure for HIV infection remains elus... |
20860051 | Revisiting an old friend: manganese-based MRI contrast agents. | Non-invasive cellular and molecular imaging techniques are emerging as a multidisciplinary field that offers promise in understanding ponents, processes, dynamics and therapies of disease at a molecular level. Magnetic resonance imaging (MRI) is an attractive technique due to the absence of radiation and high spatial r... |
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