Pubmed Text
Collection
Collection of pubmed 2024 papers. • 11 items • Updated
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24210787 | [Internet and video games among students of Reunion Island in 2010: uses, misuses, perceptions and associated factors]. | Describe the uses of Internet and video games and quantify associated problematic uses. |
24210788 | How to interpret and choose a Bayesian spatial model and a Poisson regression model in the context of describing small area cancer risks variations. | The statistical Bayesian approach is widely used in disease mapping and Poisson regression. Results differ depending on the underlying hypothesis. Our objective is to give prehensive presentation of the tools that can be used to interpret results and choose between the different hypotheses. Data from the Isere cancer r... |
24210789 | Effect of treatment of vitamin D deficiency and insufficiency during pregnancy on fetal growth indices and maternal weight gain: a randomized clinical trial. | To determine whether treatment of low serum vitamin D in pregnant women improves fetal growth indices. |
24210790 | Evaluation of serum anti-Mullerian hormone levels to assess the ovarian reserve in women with severe endometriosis. | The aim of this study was to measure anti-Mullerian hormone (AMH) serum levels in women with severe endometriosis, in order to demonstrate the effect of the disease on ovarian reserve. |
24210791 | Anterior needle-guided mesh in advanced pelvic organ prolapse: apical fixation on sacrospinous ligaments. | To evaluate whether partment mesh implants for pelvic floor reconstruction might be safely and effectively anchored to the sacro-spinous (SS) ligaments instead of the arcus tendineus fascia pelvis (ATFP). The SS ligaments as anchoring structures for centro-apical support mesh fixation are thought to be stronger than th... |
24210792 | Spatial organization of xylem cell walls by ROP GTPases and microtubule-associated proteins. | Proper patterning of cellulosic cell walls is critical for cell shaping and differentiation of plant cells. Cortical microtubule arrays regulate the deposition patterns of cellulose microfibrils by controlling the targeting and trajectory of cellulose plexes. Although some microtubule-associated proteins (MAPs) regulat... |
24210794 | Muscular responses to handle perturbation with different glove condition. | Effect of wearing gloves on timely muscle reaction to stabilize handle perturbation was investigated. Thirteen adults gripped a horizontal overhead handle to which an upward force was applied at a random time. Muscle reaction time, integrated EMGs for eight muscles, and handle displacement pared among three glove condi... |
24210795 | Loading and knee flexion after stroke: Less does not equal more. | It is believed that force feedback can modulate lower extremity extensor activity during gait. The purpose of this research was to determine the role of limb loading on knee extensor excitability during the late stance/early swing phase of gait in persons post-stroke. Ten subjects with chronic hemiparesis post-stroke p... |
24210793 | GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice. | Innate and adaptive immune responses can speed nigrostriatal neurodegeneration in Parkinson's disease (PD). We posit that GM-CSF can attenuate such responses. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxicated mice, GM-CSF given prior to MPTP protected nigral dopaminergic neurons coincident with altered... |
24210796 | Slow expiration reduces sternocleidomastoid activity and increases transversus abdominis and internal oblique muscle activity during abdominal curl-up. | The aim of this study was to investigate the effects of quiet inspiration versus slow expiration on sternocleidomastoid (SCM) and abdominal muscle activity during abdominal curl-up in healthy subjects. Twelve healthy subjects participated in this study. Surface electromyography (EMG) was used to collect activity of bil... |
24210797 | The latest evidence on target selection in deep brain stimulation for Parkinson's disease. | Deep brain stimulation (DBS) is one of the most promising neuromodulatory techniques to gain momentum over the last 20years, with significant evidence showing the benefit of DBS for Parkinson's disease (PD). However, many questions still exist pertaining to the optimal placement of stimulation contacts. This paper aims... |
24210799 | Spontaneous cervical intradural disc herniation. | Cervical intradural disc herniation (IDH) is a rare condition with very few case reports in the literature. We report a 64-year-old man who presented with sudden onset neck pain and rapidly progressing weakness in the left upper and lower limb. There was no history of trauma. MRI of the cervical spine showed a C6-C7 di... |
24210798 | Changes in serum interleukin-33 levels in patients with acute cerebral infarction. | Inflammation is widely considered to be involved in the pathogenesis of cerebral ischemic injury. The balance between inflammatory and anti-inflammatory factors significantly affects the prognosis of patients with cerebral infarction. Interleukin-33 (IL-33), a newly identified member of the interkeukin-1 superfamily, h... |
24210800 | Brainstem encephalitis caused by Coxiella burnetii. | Coxiella burnetii is the causative agent of Q fever, which rarely causes neurologic symptoms. We describe a patient who presented with progressive sensory changes, dizziness, and motor weakness. The cerebrospinal fluid revealed pleocytosis, and MRI indicated the presence of a diffuse brain stem lesion. An indirect immu... |
24210801 | Panophthalmoplegia and vision loss after cosmetic nasal dorsum injection. | We report a case of unilateral blindness and panophthalmoplegia after hyaluronic acid injection into the dorsum of the nose in a healthy young woman. Microspheres of hyaluronic acid are popular fillers for facial rejuvenation. While ocular side effects from injections in the nose and face have been reported following t... |
24210802 | Deep brain stimulator-induced diaphoresis in Parkinson's disease patients. | We report an unusual finding of bilateral facial and corporeal diaphoresis and sensation of heat during deep brain stimulation in two patients. Stimulation of the hypothalamospinal tract located medial to the subthalamic nucleus is likely to be responsible for this side effect. |
24210803 | Acute inferior homonymous quandrantanopia in a 71-year-old woman. | A 71-year-old woman presented with acute inferior homonymous quadrantanopia initially mimicking acute ischemic stroke. As clinical signs and symptoms progressed to akinetic mutism with myoclonus the diagnosis of the Heidenhain variant of Creutzfeldt-Jakob disease was made. Brain MRI 4 days after symptom onset revealed ... |
24210805 | Post-surgical thoracic pseudomeningocele causing spinal cord compression. | Pseudomeningoceles are extradural cerebrospinal fluid collections categorized into three groups: traumatic, congenital, and iatrogenic. Iatrogenic pseudomeningoceles occur after durotomy, usually after cervical or lumbar spine surgery. Although many remain asymptomatic, pseudomeningoceles press or herniate the spinal c... |
24210804 | Successful resection of anterior and anterolateral lesions at the craniovertebral junction using a simple posterolateral approach. | Tumors at the craniovertebral junction (CVJ) often present a challenge due to proximity to vital neurovascular structures. In the last few decades, many authors have plex surgical approaches to access pathologies located anterior or anterolateral to the CVJ with the hopes of reducing morbidity. We propose that the simp... |
24210806 | Brain metastasis from extramammary Paget's disease of the scrotum. | We present to our knowledge the first patient with histopathologically proven brain metastasis from extramammary Paget's disease (EMPD) and discuss the effect of brain radiation therapy for this condition. A 68-year-old man presented to our hospital with headache and gait disturbance. Brain MRI showed multiple enhancin... |
24210807 | Endoscopic transnasal resection of ameloblastoma with intracranial extension. | Ameloblastoma is a rare odontogenic tumor with characteristics of epithelial tissue that produces enamel for the developing tooth. This lesion is generally considered benign, but has malignant forms that invade locally and metastasize. We present a 60-year-old man with maxillary ameloblastoma that after multiple recurr... |
24210808 | ²¹³Bi-anti-EGFR radioimmunoconjugates and X-ray irradiation trigger different cell death pathways in squamous cell carcinoma cells. | Treatment of patients with squamous cell carcinoma of head and neck is hampered by resistance of tumor cells to irradiation. Additional therapies enhancing the effect of X-ray irradiation may be beneficial. Antibodies targeting EGFR have been shown to improve the efficacy of radiation therapy. Therefore, we analyzed cy... |
24210809 | [The role of multimodality imaging in the diagnosis of constrictive pericarditis]. | Constrictive pericarditis is a rare heart disease. The diagnosis remains a challenge. In fact, this illness can mimic restrictive cardiomyopathy. Echo-Doppler evaluation helps to establish the diagnosis of constriction; however, this technique is limited in its ability to image the entire pericardium because of its lim... |
24210811 | Characterization of betaine aldehyde dehydrogenase (BetB) as an essential virulence factor of Brucella abortus. | The pathogenic mechanisms of Brucellosis used to adapt to the harsh intracellular environment of the host cell are not fully understood. The present study investigated the in vitro and in vivo characteristics of B. abortus betaine aldehyde dehydrogenase (BetB) (Gene Bank ID: 006932) using a betB deletion mutant constru... |
24210810 | Reversible overexpression of bace1-cleaved neuregulin-1 N-terminal fragment induces schizophrenia-like phenotypes in mice. | Neuregulin-1 (Nrg1) is a pleiotropic signaling molecule that regulates neural development, and mutation of Nrg1 is a risk factor for schizophrenia. Cleavage of type I β1 Nrg1 isoform by Bace1 releases a secreted N-terminal fragment (Nrg1-ntfβ), which can bind to a cognate ErbB receptor to activate the specific signalin... |
24210812 | Genotypes and antibiotic resistance of canine Campylobacter jejuni isolates. | Campylobacter jejuni is the most important cause of bacterial gastroenteritis in humans. It is mensal in many wild and domestic animals, including dogs. Whereas genotypes of human and chicken C. jejuni isolates have been described in some detail, only little information on canine C. jejuni genotypes is available. To ga... |
24210813 | Ultrasonic enhancement of battery diffusion. | It has been demonstrated that sonic energy can be harnessed to enhance convection in Galvanic cells during cyclic voltammetry; however, the practical value of this approach is limited due to the lack of open volumes for convection patterns to develop in most batteries. This study evaluates the ability of ultrasonic wav... |
24210814 | Sonication assisted assemblage of exotic polymer supported nanostructured bio-hybrid system and prospective application. | This work was focused on sonication mediated immobilization of porcine pancreatic lipase (PPL) onto poly(ethylene glycol) supported silver-iron oxide hybrid nanoparticles (PEG-Ag/IONPs). Selected process parameters of sonication were optimized using response surface methodology. Sonication assisted assemblage of spheri... |
24210815 | Local functional overconnectivity in posterior brain regions is associated with symptom severity in autism spectrum disorders. | Although growing evidence indicates atypical long-distance connectivity in autism spectrum disorder (ASD), much less is known about local connectivity, despite conjectures that local overconnectivity may be causally involved in the disorder. Using functional connectivity MRI and graph theory, we found that local functi... |
24210816 | Autoregulation of connexin43 gap junction formation by internally translated isoforms. | During each heartbeat, intercellular electrical coupling via connexin43 (Cx43) gap junctions enables synchronous cardiac contraction. In failing hearts, impaired Cx43 trafficking reduces gap junction coupling, resulting in arrhythmias. Here we report that internal translation within Cx43 (GJA1) mRNA occurs, resulting i... |
24210817 | SHARPIN regulates uropod detachment in migrating lymphocytes. | SHARPIN-deficient mice display a multiorgan chronic inflammatory phenotype suggestive of altered leukocyte migration. We therefore studied the role of SHARPIN in lymphocyte adhesion, polarization, and migration. We found that SHARPIN localizes to the trailing edges (uropods) of both mouse and human chemokine-activated ... |
24210818 | 27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth. | To date, estrogen is the only known endogenous estrogen receptor (ER) ligand that promotes ER+ breast tumor growth. We report that the cholesterol metabolite 27-hydroxycholesterol (27HC) stimulates MCF-7 cell xenograft growth in mice. More importantly, in ER+ breast cancer patients, 27HC content in normal breast tissue... |
24210819 | Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta. | Alzheimer's disease (AD) is characterized by the accumulation of amyloid beta (Aβ) that is assumed to result from impaired elimination of this neurotoxic peptide. Most patients with AD also exhibit cerebral amyloid angiopathy, which consists of Aβ deposition within the cerebral vasculature. The contribution of monocyte... |
24210820 | SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease. | Nonalcoholic fatty liver disease is the mon chronic liver disorder in developed countries. Its pathogenesis is poorly understood, and therapeutic options are limited. Here, we show that SIRT7, an NAD(+)-dependent H3K18Ac deacetylase, functions at chromatin to suppress ER stress and prevent the development of fatty live... |
24210821 | Brain hyperconnectivity in children with autism and its links to social deficits. | Autism spectrum disorder (ASD), a neurodevelopmental disorder affecting nearly 1 in 88 children, is thought to result from aberrant brain connectivity. Remarkably, there have been no systematic attempts to characterize whole-brain connectivity in children with ASD. Here, we use neuroimaging to show that there are more ... |
24210822 | Specificity of monosynaptic sensory-motor connections imposed by repellent Sema3E-PlexinD1 signaling. | In mammalian spinal cord, group Ia proprioceptive afferents form selective monosynaptic connections with a select group of motor pool targets. The extent to which sensory recognition of motor neurons contributes to the selectivity of sensory-motor connections remains unclear. We show here that proprioceptive sensory af... |
24210823 | DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells. | The ubiquitin-modification status of proteins in cells is highly dynamic and maintained by specific ligation machineries (E3 ligases) that tag proteins with ubiquitin or by deubiquitinating enzymes (DUBs) that remove the ubiquitin tag. The development of tools that offset this balance is critical in characterizing sign... |
24210824 | Changes in cellular mRNA stability, splicing, and polyadenylation through HuR protein sequestration by a cytoplasmic RNA virus. | The impact of RNA viruses on the posttranscriptional regulation of cellular gene expression is unclear. Sindbis virus causes a dramatic relocalization of the cellular HuR protein from the nucleus to the cytoplasm in infected cells. This is to the result of the expression of large amounts of viral RNAs that contain high... |
24210826 | High-frequency promoter firing links THO complex function to heavy chromatin formation. | The plex is involved in transcription, genome stability, and messenger ribonucleoprotein (mRNP) formation, but its precise molecular function remains enigmatic. Under heat shock conditions, THO mutants accumulate large plexes that alter the chromatin density of target genes (heavy chromatin), defining a specific bioche... |
24210825 | High-resolution replication profiles define the stochastic nature of genome replication initiation and termination. | Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution Saccharomyces cerevisiae genome replication data with a mathematical model allows quantification of the stochastic nature of genome replication, including the effic... |
24210828 | The effects of long-term therapy with proton pump inhibitors on meal stimulated gastrin. | Dyspepsia develops in healthy volunteers after withdrawal of proton-pump inhibitors. This phenomenon, attributed to rebound acid hypersecretion, is thought to be mediated by reflex hypergastrinemia. |
24210827 | Roles of exonucleases and translesion synthesis DNA polymerases during mitotic gap repair in yeast. | Transformation-based gap-repair assays have long been used to model the repair of mitotic double-strand breaks (DSBs) by homologous bination in yeast. In the current study, we examine genetic requirements of two key processes involved in DSB repair: (1) the processive 5'-end resection that is required to efficiently en... |
24210829 | Clinicopathologic characteristics and outcomes of penile cancer treated at tertiary care centers in the Western United States. | This article reports on the experience with penile squamous cell carcinoma (PSCC) in a unique multiethnic patient population from Los Angeles, California, with regard to treatments rendered and clinical es. |
24210830 | Repair of posterior mitral valve prolapse with a novel leaflet plication clip in an animal model. | Recently, there has been increased interest in minimally invasive mitral valve prolapse repair techniques; however, these techniques have limitations. A new technique was developed for treating mitral valve prolapse that uses a novel leaflet plication clip to selectively plicate the prolapsed leaflet segment. The clip'... |
24210831 | Dexamethasone levels predict cortisol response after infant cardiopulmonary bypass. | We sought to evaluate whether there is variability in blood dexamethasone levels after a standard 1 mg/kg dose of dexamethasone administered before infant cardiopulmonary bypass. We hypothesized that postoperative dexamethasone drug levels are highly variable, and that the infant stress response is related inversely to... |
24210834 | Comparing robot-assisted thoracic surgical lobectomy with conventional video-assisted thoracic surgical lobectomy and wedge resection: results from a multihospital database (Premier). | Video-assisted thoracic surgical (VATS) lobectomies and wedge resections result in less morbidity and shorter length of stay than resections via thoracotomy. The impact of robot-assisted thoracic surgical (RATS) lobectomy on clinical and economic es has not been examined. This pared hospital costs and clinical es for V... |
24210835 | Genotype-oropharyngeal phenotype correlation in Mexican patients with dystrophic epidermolysis bullosa. | Previous investigations have attempted to correlate the genotype with the cutaneous phenotype in patients with epidermolysis bullosa (EB), but never with the oropharyngeal phenotype. Seventeen dystrophic EB (DEB) patients were genotyped for COL7A1 gene mutations and divided into five distinct groups. Oropharyngeal dise... |
24210838 | What is the value of historical fidelity in restoration? | The following considers the role of historical fidelity in habitat reconstruction efforts. To what extent should habitat reconstruction be guided by the goal of recreating some past state of a damaged ecosystem? I consider Sarkar's "replacement argument," which holds that, in most habitat reconstruction efforts, there ... |
24210839 | Effects of albumin and synthetic polypeptide-coated oxygenators on IL-1, IL-2, IL-6, and IL-10 in open heart surgery. | In this study, we have tried to demonstrate the effects of coating style used in oxygenators on various hematologic and clinical parameters. |
24210836 | Does acute passive stretching increase muscle length in children with cerebral palsy? | Children with spastic cerebral palsy experience increased muscle stiffness and reduced muscle length, which may prevent elongation of the muscle during stretch. Stretching performed either by the clinician, or children themselves is used as a treatment modality to increase/maintain joint range of motion. It is not clea... |
24210837 | Relationship of plasma cytokines and clinical biomarkers to memory performance in HIV. | Chronic systemic immune activation and inflammatory processes have been linked to brain dysfunction in medically stable HIV-infected people. We investigated the association between verbal memory performance and plasma concentrations of 13 cytokines measured using multiplexed bead array immunoassay in 74 HIV-seropositiv... |
24210840 | Behavioral compliance for dynamic versus static signs in an immersive virtual environment. | This study used an immersive virtual environment (IVE) to examine how dynamic features in signage affect pliance during a work-related task and an emergency egress. Ninety participants performed a work-related task followed by an emergency egress. Compliance with uncued and cued safety signs was assessed prior to an ex... |
24210842 | A study to promote breast feeding in the Helsinki Metropolitan area in Finland. | the aim of this study was to assess the impact of providing intensified support for breast feeding during the perinatal period. |
24210843 | Computer-assisted training of phoneme-grapheme correspondence for children who are deaf and hard of hearing: effects on phonological processing skills. | Examine deaf and hard of hearing (DHH) children's phonological processing skills in relation to a reference group of children with normal hearing (NH) at two baselines pre intervention. Study the effects puter-assisted phoneme-grapheme correspondence training in the children. Specifically analyze possible effects on DH... |
24210844 | A new device for treatment of persistent otitis media with effusion. | Most children suffer from otitis media with effusion (OME) before starting school. Insertion of grommets into the eardrum for treatment of OME is one of the mon operations performed in childhood. The efficiency pliance of treatment with a new non-invasive device was evaluated in children with bilateral OME with disease... |
24210845 | Streptococcal superantigens: categorization and clinical associations. | Superantigens are key virulence factors in the immunopathogenesis of invasive disease caused by group A streptococcus. These protein exotoxins have also been associated with severe group C and group G streptococcal infections. A number of novel streptococcal superantigens have recently been described with some resultin... |
24210847 | Stump infections after major lower-limb amputation: a 10-year retrospective study. | There is little published data on the diagnostic and therapeutic management of lower-limb stump infections (excluding toe and forefoot amputations). |
24210848 | Evaluation of a subject-specific finite-element model of the equine metacarpophalangeal joint under physiological load. | The equine metacarpophalangeal (MCP) joint is frequently injured, especially by racehorses in training. Most injuries result from repetitive loading of the subchondral bone and articular cartilage rather than from acute events. The likelihood of injury is multi-factorial but the magnitude of mechanical loading and the ... |
24210849 | Murine patellar tendon biomechanical properties and regional strain patterns during natural tendon-to-bone healing after acute injury. | Tendon-to-bone healing following acute injury is generally poor and often fails to restore normal tendon biomechanical properties. In recent years, the murine patellar tendon (PT) has e an important model system for studying tendon healing and repair due to its genetic tractability and accessible location within the kn... |
24210850 | Walking at the preferred stride frequency maximizes local dynamic stability of knee motion. | Healthy humans display a preference for walking at a stride frequency dependent on the inertial properties of their legs. Walking at preferred stride frequency (PSF) is predicted to maximize local dynamic stability, whereby sensitivity to intrinsic perturbations arising from natural variability inherent in biological m... |
24210851 | Pediatric bed fall computer simulation model: parametric sensitivity analysis. | Falls from beds and other household furniture mon scenarios that may result in injury and may also be stated to conceal child abuse. Knowledge of the biomechanics associated with short-distance falls may aid clinicians in distinguishing between abusive and accidental injuries. In this study, a validated bed puter simul... |
24210852 | Quantification of finger joint loadings using musculoskeletal modelling clarifies mechanical risk factors of hand osteoarthritis. | Owing to limited quantitative data related to the loadings (forces and pressures) acting upon finger joints, several clinical observations regarding mechanical risk factors of hand osteoarthritis remain misunderstood. To improve the knowledge of this pathology, the present study used musculoskeletal modelling to quanti... |
24210854 | Effect of swirling inlet condition on the flow field in a stenosed arterial vessel model. | Blood flow in an artery is closely related to atherosclerosis progression. Hemodynamic environments influence platelet activation, aggregation, and rupture of atherosclerotic plaque. The existence of swirling ponents in an artery is frequently observed under in vivo conditions. However, the fluid-dynamic roles of spira... |
24210853 | Molecular markers of programmed cell death in donor hearts before transplantation. | In this study we investigate whether pro-apoptotic, pro-inflammatory and other early signaling markers indicative of increased propensity for cell death processes were evident in human donor heart allografts immediately before transplantation, and whether there is an association with primary graft failure. |
24210855 | Bile and liver metallothionein behavior in copper-exposed fish. | The present study analyzed metallothionein (MT) excretion from liver to bile in Nile Tilapia (Oreochromis niloticus) exposed to sub-lethal copper concentrations (2mgL(-1)) in a laboratory setting. MTs in liver and bile were quantified by spectrophotometry after thermal incubation and MT metal-binding profiles were char... |
24210856 | Ultrasound thermal mapping based on a hybrid method combining physical and statistical models. | Non-invasive temperature measurement of tissues deep inside the body has great potential for clinical applications, such as temperature monitoring during thermal therapy and early diagnosis of diseases. We developed a novel method for both temperature estimation and thermal mapping that uses ultrasound B-mode radiofreq... |
24210857 | 3-D high-frequency ultrasound backscatter analysis of human articular cartilage. | High-frequency ultrasound is a promising method for non-invasive characterization of cartilage degeneration. Surface reflection and integrated spectral parameters are often used. In the work described here, human cartilage samples with varying degrees of degeneration were measured using a 40-MHz transducer. Backscatter... |
24210858 | Muscle ultrasound quantifies segmental neuromuscular outcome in pediatric myelomeningocele. | In pediatric spina bifida aperta (SBA), non-invasive assessment of neuromuscular integrity by muscle ultrasound density (MUD) could provide important information about the clinical condition. We therefore aimed to determine the association between pediatric SBA MUD and segmental neurologic function. We included 23 chil... |
24210859 | Ultra-high frame rate tissue Doppler imaging. | We describe a new tissue Doppler imaging (TDI) method, ultra-high frame rate tissue Doppler imaging (UFR-TDI). With two broad transmit beams covering only the ventricular walls, we achieve 1200 frames/s in a four-chamber apical view. We examined 10 healthy volunteers to study the feasibility of this method. Ultra-high-... |
24210860 | Comparison of diffuse optical tomography, ultrasound elastography and mammography in the diagnosis of breast tumors. | Previous studies have reported the usefulness of diffuse optical tomography (DOT), ultrasound elastography (UE) and mammography in differentiating breast tumors. This study was aimed at evaluating paring DOT, UE and mammography with respect to their diagnostic performance in differentiating benign and malignant breast ... |
24210861 | Shear wave elastography assessment of carotid plaque stiffness: in vitro reproducibility study. | This study assessed inter- and intra-observer reproducibility of shear wave elastography (SWE) measurements in vessel phantoms simulating soft and hard carotid plaque under steady and pulsatile flow conditions. Supersonic SWE was used to acquire cine-loop data and quantify Young's modulus in cryogel vessel phantoms. Da... |
24210862 | Transverse ultrasound assessment of median nerve deformation and displacement in the human carpal tunnel during wrist movements. | The symptoms of carpal tunnel syndrome, pression neuropathy of the median nerve at the wrist, are aggravated by wrist motion, but the effect of these motions on median nerve motion are unknown. To better understand the biomechanics of the abnormal nerve, it is first necessary to understand normal nerve movement. The pu... |
24210863 | Visualizing tendon elasticity in an ex vivo partial tear model. | Supersonic shear imaging (SSI) is evaluated as a means of visualizing changes in regional tendon elasticity caused by partial tears in a porcine model. Thirty digital flexor tendons were cut to 25% (n = 10), 50% (n = 10) and 75% (n = 10) of the tendon thickness along the deep surface. Tendon elasticity was mapped left ... |
24210864 | A novel microfluidic chip for assessing dynamic adhesion behavior of cell-targeting microbubbles. | The primary aim of this study was to develop a microfluidic chip to study the dynamic adhesion behavior of cell-targeted microbubbles. The microfluidic device posed of polydimethylsiloxane and is fabricated using the soft lithography technique. Each chamber of the microfluidic prises eight U-shaped microsieves, by whic... |
24210865 | Doppler vortography: a color Doppler approach to quantification of intraventricular blood flow vortices. | We propose a new approach to quantification of intracardiac vorticity based on conventional color Doppler images -Doppler vortography. Doppler vortography relies on the centrosymmetric properties of the vortices. Such properties induce particular symmetries in the Doppler flow data that can be exploited to describe the... |
24210866 | Correlation of virulence genes to clinical manifestations and outcome in patients with Streptococcus dysgalactiae subspecies equisimilis bacteremia. | Streptococcus dysgalactiae subsp. equisimilis (SDSE) is increasingly recognized as a human pathogen responsible for invasive infection and streptococcal toxic shock syndrome (STSS). The pathogen possesses virulence genes that resemble those found in Streptococcus pyogenes (GAS). We analyzed the association between thes... |
24210867 | Effectiveness of montelukast in pediatric patients with allergic rhinitis. | Allergic rhinitis (AR) is one of the mon chronic diseases of childhood and carries significant morbidity as well as physical and psychosocial consequences. Therapy aims to alleviate clinical symptoms, plications and improve psychosocial consequences. Leukotrienes which are amongst the main mediators in pathogenesis of ... |
24210868 | A usability evaluation of medical software at an expert conference setting. | A usability test was employed to evaluate two medical software applications at an expert conference setting. One software application is a medical diagnostic tool (electrocardiogram [ECG] viewer) and the other is a medical research tool (electrode misplacement simulator [EMS]). These novel applications have yet to be a... |
24210869 | A haptic pedal for surgery assistance. | The research and development of mechatronic aids for surgery is a persistent challenge in the field of robotic surgery. This paper presents a new haptic pedal conceived to assist surgeons in the operating room by transmitting real-time surgical information through the foot. An effective human-robot interaction system f... |
24210870 | Differential correlations between inflammatory cytokines and psychopathology in veterans with schizophrenia: potential role for IL-17 pathway. | Pro-inflammatory cytokines have been consistently reported to be elevated in schizophrenia patients. However, it is not known whether cytokines influence the presentation of psychotic symptoms. To address this issue, we evaluated the relationship between levels of inflammatory molecules and psychopathological parameter... |
24210871 | Can P300 distinguish among schizophrenia, schizoaffective and bipolar I disorders? An ERP study of response inhibition. | Research utilizing visual event-related brain potentials (ERPs) has demonstrated that reduced P300 amplitude and prolonged latency may qualify as a biological marker (biomarker) for schizophrenia (SZ). We examined P300 characteristics in response inhibition among three putatively distinct psychopathology groups includi... |
24210872 | A review of ligand tethered surface engineered carbon nanotubes. | Carbon nanotubes (CNTs) have emerged as fascinating materials, exhibiting promising potential in receptor based targeting owing to their unique physicochemical properties (cell membrane penetration, high surface area and drug payload, patibility, easy surface modification, photoluminescence property, and non-immunogeni... |
24210874 | Control of angiogenesis by VEGF and endostatin-encapsulated protein microcrystals and inhibition of tumor angiogenesis. | Encapsulation of cytokines within protein microcrystals (polyhedra) is a promising approach for the stabilization and delivery of therapeutic proteins. Here, we investigate the influence of vascular endothelial growth factor (VEGF) microcrystals and endostatin microcrystals on angiogenesis. VEGF was successfully encaps... |
24210873 | Mechanoregulation of valvular interstitial cell phenotype in the third dimension. | A quantitative understanding of plex interactions between cells, soluble factors, and the biological and mechanical properties of biomaterials is required to guide cell remodeling toward regeneration of healthy tissue rather than fibrocontractive tissue. In the present study, we characterized bined effects of boundary ... |
24210875 | Nanoparticle-directed sub-cellular localization of doxorubicin and the sensitization breast cancer cells by circumventing GST-mediated drug resistance. | Resistance to single or multiple chemotherapeutic drugs is a plication in clinical oncology and is one of the mon treatment limitations in patients with reoccurring cancers. Nanoparticle (NP)-based drug delivery systems (DDS's) have been shown to e drug resistance in cancer cells mainly by avoiding the activation of ef... |
24210876 | Relationship between conventional semen characteristics, sperm motility patterns and fertility of Andalusian donkeys (Equus asinus). | Sperm quality has an important role in determining fertility. The aims of this study were pare the conventional sperm parameters, plus the characteristics of the motility patterns of the different sperm subpopulations, of donkey donors with different fertility level, and to determine their relationships to fertility. T... |
24210877 | The research of nanoparticles as gene vector for tumor gene therapy. | With the development of molecular biology, the application of the gene therapy es a tendency in the development of oncotherapy. The gene therapy has been acknowledged as the major progress of modern medicine, also a focus in the oncotherapy research. Commonly vectors of the gene therapy mainly include two categories, n... |
24210878 | The positive effects of the revised milk and cheese allowances in the special supplemental nutrition program for women, infants, and children. | In 2009, the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) implemented revisions to the WIC food packages. Milk and cheese allowances were reduced, and whole milk was disallowed for participants older than 23 months. Using a pre-post research design and scanner data from a New England su... |
24210879 | 320-Row wide volume CT significantly reduces density heterogeneity observed in the descending aorta: comparisons with 64-row helical CT. | The aim of this study was pare density heterogeneity on wide volume (WV) scans with that on helical CT scans. 22 subjects underwent chest CT using 320-WV and 64-helical modes. Density heterogeneity of the descending aorta was evaluated quantitatively and qualitatively. At qualitative assessment, the heterogeneity was j... |
24210880 | Physical fitness in pre-registration nursing students. | Nurses are ideally placed to deliver health promotion interventions, including physical fitness, however evidence suggests that nurses themselves are failing to engage in healthy lifestyles; this in turn making them less likely to promote health. It would appear that some nurses are allowing their own values, beliefs a... |
24210881 | Experiencing everyday ethics in context: frontline data collectors perspectives and practices of bioethics. | Data collectors play a vital role in producing scientific knowledge. They are also an ponent in understanding the practice of bioethics. Yet, very little attention has been given to their everyday experiences or the context in which they are expected to undertake these tasks. This paper argues that while there has been... |
24210882 | Challenging resistance mechanisms to therapies for metastatic melanoma. | Melanoma is the most aggressive form of skin cancer and, if spread outside the epidermis, has a dismal prognosis. Before the approval of the anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) monoclonal antibody ipilimumab and the BRAF inhibitors vemurafenib and dabrafenib, no other agents had demonstrated bette... |
24210883 | Dendritic cell immunoreceptor: a novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells. | Intravenous immunoglobulin (IVIg) is a polyclonal IgG preparation with potent immunomodulating properties. Our laboratory demonstrated that IVIg significantly increases numbers of forkhead box protein 3-positive regulatory T (Treg) cells through generation of tolerogenic dendritic cells (DCs) in an allergic airways dis... |
24210884 | Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma. | The airway epithelium is exposed to a range of physical and chemical irritants in the environment that are known to trigger asthma. Transient receptor potential (TRP) cation channels play a central role in sensory responses to noxious physical and chemical stimuli. Recent genetic evidence suggests an involvement of tra... |
24210886 | Brain natriuretic peptide at discharge as a predictor of 6-month mortality in acute decompensated heart failure. | Brain natriuretic peptide (BNP) is well established in detecting acute pensation of heart failure (ADHF). The role of BNP at discharge in predicting mortality is less established. Accumulating evidence suggests that inflammatory cytokines play an important role in the development of heart failure. We aimed to examine t... |
24210887 | Association between mean arterial blood gas tension and outcome in cardiac arrest patients treated with therapeutic hypothermia. | Studies investigating the relationship between blood gas tension and e in cardiac arrest survivors have reported conflicting results. This might have resulted from the use of a blood gas value at a single time point and the difference in the proportion of patients treated with therapeutic hypothermia (TH). We investiga... |
24210888 | Stress-related cardiomyopathy, ventricular dysfunction, artery thrombosis: a hidden pheochromocytoma. | Clinical presentation of pheochromocytoma can vary, and it can sometimes mimic other diseases. Some patients with pheochromocytoma may have atypical presentations, such as clinical features consistent with an acute coronary syndrome, that only later suggest a classical picture of stress-related cardiomyopathy. To our b... |
24210889 | Quality of chest compressions during compression-only CPR: a comparative analysis following the 2005 and 2010 American Heart Association guidelines. | The latest guidelines both increased the requirements of pression rate and depth during cardiopulmonary resuscitation (CPR), which may make it more difficult for the rescuer to provide high-quality pression. In this study, we investigated the quality of pressions pression-only CPR under the latest 2010 American Heart A... |
24210890 | Halogenated phenolic compound determination in plasma and serum by solid phase extraction, dansylation derivatization and liquid chromatography-positive electrospray ionization-tandem quadrupole mass spectrometry. | A robust, sensitive and accurate method was developed for the simultaneous determination in plasma and serum of suite a halogenated pounds (HPCs) for which several are known to persist in the environment and analytically pure standards are available. Namely, 14 congeners of hydroxylated polybrominated diphenyl ethers (... |
24210891 | High performance liquid chromatography with evaporative light scattering detection for the characterisation of a vesicular delivery system during stability studies. | A normal phase high performance liquid chromatography method with evaporative light scattering detection was developed for the simultaneous quantification of the lipid constituents of a non-ionic surfactant vesicle (NIV) delivery system consisting of tetra-ethylene glycol mono n-hexadecyl ether, cholesterol and dicetyl... |
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