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Washington University's North Campus and West Campus principally house administrative functions that are not student focused. North Campus lies in St. Louis City near the Delmar Loop. The University acquired the building and adjacent property in 2004, formerly home to the Angelica Uniform Factory. Several University ad... |
The West Campus is located about one mile (1.6 km) to the west of the Danforth Campus in Clayton, Missouri, and primarily consists of a four-story former department store building housing mostly administrative space. The West Campus building was home to the Clayton branch of the Famous-Barr department store until 1990,... |
Tyson Research Center is a 2,000-acre (809 ha) field station located west of St. Louis on the Meramec River. Washington University obtained Tyson as surplus property from the federal government in 1963. It is used by the University as a biological field station and research/education center. In 2010 the Living Learning... |
Arts & Sciences at Washington University comprises three divisions: the College of Arts & Sciences, the Graduate School of Arts & Sciences, and University College in Arts & Sciences. Barbara Schaal is Dean of the Faculty of Arts & Sciences. James E. McLeod was the Vice Chancellor for Students and Dean of the College of... |
Founded as the School of Commerce and Finance in 1917, the Olin Business School was named after entrepreneur John M. Olin in 1988. The school's academic programs include BSBA, MBA, Professional MBA (PMBA), Executive MBA (EMBA), MS in Finance, MS in Supply Chain Management, MS in Customer Analytics, Master of Accounting... |
Olin has a network of more than 16,000 alumni worldwide. Over the last several years, the school’s endowment has increased to $213 million (2004) and annual gifts average $12 million per year.[citation needed] Simon Hall was opened in 1986 after a donation from John E. Simon. On May 2, 2014, the $90 million conjoined K... |
Undergraduate BSBA students take 40–60% of their courses within the business school and are able to formally declare majors in eight areas: accounting, entrepreneurship, finance, healthcare management, marketing, managerial economics and strategy, organization and human resources, international business, and operations... |
Washington University School of Law offers joint-degree programs with the Olin Business School, the Graduate School of Arts and Sciences, the School of Medicine, and the School of Social Work. It also offers an LLM in Intellectual Property and Technology Law, an LLM in Taxation, an LLM in US Law for Foreign Lawyers, a ... |
In the 2015 US News & World Report America's Best Graduate Schools, the law school is ranked 18th nationally, out of over 180 law schools. In particular, its Clinical Education Program is currently ranked 4th in the nation. This year, the median score placed the average student in the 96th percentile of test takers. Th... |
The Washington University School of Medicine, founded in 1891, is highly regarded as one of the world's leading centers for medical research and training. The School ranks first in the nation in student selectivity. Among its many recent initiatives, The Genome Center at Washington University (directed by Richard K. Wi... |
With roots dating back to 1909 in the university's School of Social Economy, the George Warren Brown School of Social Work (commonly called the Brown School or Brown) was founded in 1925. Brown's academic degree offerings include a Master of Social Work (MSW), a Master of Public Health (MPH), a PhD in Social Work, and ... |
The school has many nationally and internationally acclaimed scholars in social security, health care, health disparities, communication, social and health policy, and individual and family development. Many of the faculty have training in both social work and public health. The school's current dean is Edward F. Lawlo... |
The Mildred Lane Kemper Art Museum, established in 1881, is one of the oldest teaching museums in the country. The collection includes works from 19th, 20th, and 21st century American and European artists, including George Caleb Bingham, Thomas Cole, Pablo Picasso, Max Ernst, Alexander Calder, Jackson Pollock, Rembrand... |
Virtually all faculty members at Washington University engage in academic research,[citation needed] offering opportunities for both undergraduate and graduate students across the university's seven schools. Known for its interdisciplinarity and departmental collaboration, many of Washington University's research cente... |
During fiscal year 2007, $537.5 million was received in total research support, including $444 million in federal obligations. The University has over 150 National Institutes of Health funded inventions, with many of them licensed to private companies. Governmental agencies and non-profit foundations such as the NIH, U... |
Washington University has over 300 undergraduate student organizations on campus. Most are funded by the Washington University Student Union, which has a $2 million plus annual budget that is completely student-controlled and is one of the largest student government budgets in the country. Known as SU for short, the St... |
Washington University has a large number of student-run musical groups on campus, including 12 official a cappella groups. The Pikers, an all-male group, is the oldest such group on campus. The Greenleafs, an all-female group is the oldest (and only) female group on campus. The Mosaic Whispers, founded in 1991, is the ... |
Over 50% of undergraduate students live on campus. Most of the residence halls on campus are located on the South 40, named because of its adjacent location on the south side of the Danforth Campus and its size of 40 acres (160,000 m2). It is the location of all the freshman buildings as well as several upperclassman b... |
Another group of residences, known as the Village, is located in the northwest corner of Danforth Campus. Only open to upperclassmen and January Scholars, the North Side consists of Millbrook Apartments, The Village, Village East on-campus apartments, and all fraternity houses except the Zeta Beta Tau house, which is o... |
Washington University supports four major student-run media outlets. The university's student newspaper, Student Life, is available for students. KWUR (90.3 FM) serves as the students' official radio station; the station also attracts an audience in the immediately surrounding community due to its eclectic and free-for... |
Washington University's sports teams are called the Bears. They are members of the National Collegiate Athletic Association and participate in the University Athletic Association at the Division III level. The Bears have won 19 NCAA Division III Championships— one in women's cross country (2011), one in men's tennis (2... |
Unlike the Federal Bureau of Investigation (FBI), which is a domestic security service, CIA has no law enforcement function and is mainly focused on overseas intelligence gathering, with only limited domestic collection. Though it is not the only U.S. government agency specializing in HUMINT, CIA serves as the national... |
The Executive Office also supports the U.S. military by providing it with information it gathers, receiving information from military intelligence organizations, and cooperating on field activities. The Executive Director is in charge of the day to day operation of the CIA, and each branch of the service has its own Di... |
The Directorate of Analysis produces all-source intelligence investigation on key foreign and intercontinental issues relating to powerful and sometimes anti-government sensitive topics. It has four regional analytic groups, six groups for transnational issues, and three focus on policy, collection, and staff support. ... |
The Directorate of Operations is responsible for collecting foreign intelligence, mainly from clandestine HUMINT sources, and covert action. The name reflects its role as the coordinator of human intelligence activities among other elements of the wider U.S. intelligence community with their own HUMINT operations. This... |
The CIA established its first training facility, the Office of Training and Education, in 1950. Following the end of the Cold War, the CIA's training budget was slashed, which had a negative effect on employee retention. In response, Director of Central Intelligence George Tenet established CIA University in 2002. CIA ... |
Details of the overall United States intelligence budget are classified. Under the Central Intelligence Agency Act of 1949, the Director of Central Intelligence is the only federal government employee who can spend "un-vouchered" government money. The government has disclosed a total figure for all non-military intelli... |
There were numerous previous attempts to obtain general information about the budget. As a result, it was revealed that CIA's annual budget in Fiscal Year 1963 was US $550 million (inflation-adjusted US$ 4.3 billion in 2016), and the overall intelligence budget in FY 1997 was US $26.6 billion (inflation-adjusted US$ 39... |
The role and functions of the CIA are roughly equivalent to those of the United Kingdom's Secret Intelligence Service (the SIS or MI6), the Australian Secret Intelligence Service (ASIS), the Egyptian General Intelligence Service, the Russian Foreign Intelligence Service (Sluzhba Vneshney Razvedki) (SVR), the Indian Res... |
The closest links of the U.S. IC to other foreign intelligence agencies are to Anglophone countries: Australia, Canada, New Zealand, and the United Kingdom. There is a special communications marking that signals that intelligence-related messages can be shared with these four countries. An indication of the United Stat... |
The success of the British Commandos during World War II prompted U.S. President Franklin D. Roosevelt to authorize the creation of an intelligence service modeled after the British Secret Intelligence Service (MI6), and Special Operations Executive. This led to the creation of the Office of Strategic Services (OSS). O... |
Lawrence Houston, head counsel of the SSU, CIG, and, later CIA, was a principle draftsman of the National Security Act of 1947 which dissolved the NIA and the CIG, and established both the National Security Council and the Central Intelligence Agency. In 1949, Houston would help draft the Central Intelligence Agency Ac... |
At the outset of the Korean War the CIA still only had a few thousand employees, a thousand of whom worked in analysis. Intelligence primarily came from the Office of Reports and Estimates, which drew its reports from a daily take of State Department telegrams, military dispatches, and other public documents. The CIA s... |
The CIA had different demands placed on it by the different bodies overseeing it. Truman wanted a centralized group to organize the information that reached him, the Department of Defense wanted military intelligence and covert action, and the State Department wanted to create global political change favorable to the U... |
US army general Hoyt Vandenberg, the CIG's second director, created the Office of Special Operations (OSO), as well as the Office of Reports and Estimates (ORE). Initially the OSO was tasked with spying and subversion overseas with a budget of $15 million, the largesse of a small number of patrons in congress. Vandenbe... |
On 18 June 1948, the National Security Council issued Directive 10/2 calling for covert action against the USSR, and granting the authority to carry out covert operations against "hostile foreign states or groups" that could, if needed, be denied by the U.S. government. To this end, the Office of Policy Coordination wa... |
The early track record of the CIA was poor, with the agency unable to provide sufficient intelligence about the Soviet takeovers of Romania and Czechoslovakia, the Soviet blockade of Berlin, and the Soviet atomic bomb project. In particular, the agency failed to predict the Chinese entry into the Korean War with 300,00... |
Pain is a distressing feeling often caused by intense or damaging stimuli, such as stubbing a toe, burning a finger, putting alcohol on a cut, and bumping the "funny bone". Because it is a complex, subjective phenomenon, defining pain has been a challenge. The International Association for the Study of Pain's widely us... |
Pain is the most common reason for physician consultation in most developed countries. It is a major symptom in many medical conditions, and can interfere with a person's quality of life and general functioning. Psychological factors such as social support, hypnotic suggestion, excitement, or distraction can significan... |
In 1994, responding to the need for a more useful system for describing chronic pain, the International Association for the Study of Pain (IASP) classified pain according to specific characteristics: (1) region of the body involved (e.g. abdomen, lower limbs), (2) system whose dysfunction may be causing the pain (e.g.,... |
Pain is usually transitory, lasting only until the noxious stimulus is removed or the underlying damage or pathology has healed, but some painful conditions, such as rheumatoid arthritis, peripheral neuropathy, cancer and idiopathic pain, may persist for years. Pain that lasts a long time is called chronic or persisten... |
Nociceptive pain is caused by stimulation of peripheral nerve fibers that respond to stimuli approaching or exceeding harmful intensity (nociceptors), and may be classified according to the mode of noxious stimulation. The most common categories are "thermal" (e.g. heat or cold), "mechanical" (e.g. crushing, tearing, s... |
Nociceptive pain may also be divided into "visceral", "deep somatic" and "superficial somatic" pain. Visceral structures are highly sensitive to stretch, ischemia and inflammation, but relatively insensitive to other stimuli that normally evoke pain in other structures, such as burning and cutting. Visceral pain is dif... |
The prevalence of phantom pain in upper limb amputees is nearly 82%, and in lower limb amputees is 54%. One study found that eight days after amputation, 72 percent of patients had phantom limb pain, and six months later, 65 percent reported it. Some amputees experience continuous pain that varies in intensity or quali... |
Local anesthetic injections into the nerves or sensitive areas of the stump may relieve pain for days, weeks, or sometimes permanently, despite the drug wearing off in a matter of hours; and small injections of hypertonic saline into the soft tissue between vertebrae produces local pain that radiates into the phantom l... |
Paraplegia, the loss of sensation and voluntary motor control after serious spinal cord damage, may be accompanied by girdle pain at the level of the spinal cord damage, visceral pain evoked by a filling bladder or bowel, or, in five to ten per cent of paraplegics, phantom body pain in areas of complete sensory loss. T... |
People with long-term pain frequently display psychological disturbance, with elevated scores on the Minnesota Multiphasic Personality Inventory scales of hysteria, depression and hypochondriasis (the "neurotic triad"). Some investigators have argued that it is this neuroticism that causes acute pain to turn chronic, b... |
Breakthrough pain is transitory acute pain that comes on suddenly and is not alleviated by the patient's normal pain management. It is common in cancer patients who often have background pain that is generally well-controlled by medications, but who also sometimes experience bouts of severe pain that from time to time ... |
Although unpleasantness is an essential part of the IASP definition of pain, it is possible to induce a state described as intense pain devoid of unpleasantness in some patients, with morphine injection or psychosurgery. Such patients report that they have pain but are not bothered by it; they recognize the sensation o... |
A much smaller number of people are insensitive to pain due to an inborn abnormality of the nervous system, known as "congenital insensitivity to pain". Children with this condition incur carelessly-repeated damage to their tongues, eyes, joints, skin, and muscles. Some die before adulthood, and others have a reduced l... |
In 1644, René Descartes theorized that pain was a disturbance that passed down along nerve fibers until the disturbance reached the brain, a development that transformed the perception of pain from a spiritual, mystical experience to a physical, mechanical sensation[citation needed]. Descartes's work, along with Avicen... |
In 1955, DC Sinclair and G Weddell developed peripheral pattern theory, based on a 1934 suggestion by John Paul Nafe. They proposed that all skin fiber endings (with the exception of those innervating hair cells) are identical, and that pain is produced by intense stimulation of these fibers. Another 20th-century theor... |
In 1968 Ronald Melzack and Kenneth Casey described pain in terms of its three dimensions: "sensory-discriminative" (sense of the intensity, location, quality and duration of the pain), "affective-motivational" (unpleasantness and urge to escape the unpleasantness), and "cognitive-evaluative" (cognitions such as apprais... |
Wilhelm Erb's (1874) "intensive" theory, that a pain signal can be generated by intense enough stimulation of any sensory receptor, has been soundly disproved. Some sensory fibers do not differentiate between noxious and non-noxious stimuli, while others, nociceptors, respond only to noxious, high intensity stimuli. At... |
The pain signal travels from the periphery to the spinal cord along an A-delta or C fiber. Because the A-delta fiber is thicker than the C fiber, and is thinly sheathed in an electrically insulating material (myelin), it carries its signal faster (5–30 m/s) than the unmyelinated C fiber (0.5–2 m/s). Pain evoked by the ... |
Spinal cord fibers dedicated to carrying A-delta fiber pain signals, and others that carry both A-delta and C fiber pain signals up the spinal cord to the thalamus in the brain have been identified. Other spinal cord fibers, known as wide dynamic range neurons, respond to A-delta and C fibers, but also to the large A-b... |
In his book, The Greatest Show on Earth: The Evidence for Evolution, biologist Richard Dawkins grapples with the question of why pain has to be so very painful. He describes the alternative as a simple, mental raising of a "red flag". To argue why that red flag might be insufficient, Dawkins explains that drives must c... |
Differences in pain perception and tolerance thresholds are associated with, among other factors, ethnicity, genetics, and sex. People of Mediterranean origin report as painful some radiant heat intensities that northern Europeans describe as nonpainful. And Italian women tolerate less intense electric shock than Jewis... |
A person's self-report is the most reliable measure of pain, with health care professionals tending to underestimate severity. A definition of pain widely employed in nursing, emphasizing its subjective nature and the importance of believing patient reports, was introduced by Margo McCaffery in 1968: "Pain is whatever ... |
The Multidimensional Pain Inventory (MPI) is a questionnaire designed to assess the psychosocial state of a person with chronic pain. Analysis of MPI results by Turk and Rudy (1988) found three classes of chronic pain patient: "(a) dysfunctional, people who perceived the severity of their pain to be high, reported that... |
When a person is non-verbal and cannot self-report pain, observation becomes critical, and specific behaviors can be monitored as pain indicators. Behaviors such as facial grimacing and guarding indicate pain, as well as an increase or decrease in vocalizations, changes in routine behavior patterns and mental status ch... |
The experience of pain has many cultural dimensions. For instance, the way in which one experiences and responds to pain is related to sociocultural characteristics, such as gender, ethnicity, and age. An aging adult may not respond to pain in the way that a younger person would. Their ability to recognize pain may be ... |
Cultural barriers can also keep a person from telling someone they are in pain. Religious beliefs may prevent the individual from seeking help. They may feel certain pain treatment is against their religion. They may not report pain because they feel it is a sign that death is near. Many people fear the stigma of addic... |
The International Association for the Study of Pain advocates that the relief of pain should be recognized as a human right, that chronic pain should be considered a disease in its own right, and that pain medicine should have the full status of a specialty. It is a specialty only in China and Australia at this time. E... |
Sugar taken orally reduces the total crying time but not the duration of the first cry in newborns undergoing a painful procedure (a single lancing of the heel). It does not moderate the effect of pain on heart rate and a recent single study found that sugar did not significantly affect pain-related electrical activity... |
A number of meta-analyses have found clinical hypnosis to be effective in controlling pain associated with diagnostic and surgical procedures in both adults and children, as well as pain associated with cancer and childbirth. A 2007 review of 13 studies found evidence for the efficacy of hypnosis in the reduction of ch... |
Pain is the most common reason for people to use complementary and alternative medicine. An analysis of the 13 highest quality studies of pain treatment with acupuncture, published in January 2009, concluded there is little difference in the effect of real, sham and no acupuncture. However other reviews have found bene... |
Physical pain is an important political topic in relation to various issues, including pain management policy, drug control, animal rights or animal welfare, torture, and pain compliance. In various contexts, the deliberate infliction of pain in the form of corporal punishment is used as retribution for an offence, or ... |
The most reliable method for assessing pain in most humans is by asking a question: a person may report pain that cannot be detected by any known physiological measure. However, like infants (Latin infans meaning "unable to speak"), animals cannot answer questions about whether they feel pain; thus the defining criteri... |
The presence of pain in an animal cannot be known for certain, but it can be inferred through physical and behavioral reactions. Specialists currently believe that all vertebrates can feel pain, and that certain invertebrates, like the octopus, might too. As for other animals, plants, or other entities, their ability t... |
A database management system (DBMS) is a computer software application that interacts with the user, other applications, and the database itself to capture and analyze data. A general-purpose DBMS is designed to allow the definition, creation, querying, update, and administration of databases. Well-known DBMSs include ... |
Formally, a "database" refers to a set of related data and the way it is organized. Access to these data is usually provided by a "database management system" (DBMS) consisting of an integrated set of computer software that allows users to interact with one or more databases and provides access to all of the data conta... |
Physically, database servers are dedicated computers that hold the actual databases and run only the DBMS and related software. Database servers are usually multiprocessor computers, with generous memory and RAID disk arrays used for stable storage. RAID is used for recovery of data if any of the disks fail. Hardware d... |
A DBMS has evolved into a complex software system and its development typically requires thousands of human years of development effort.[a] Some general-purpose DBMSs such as Adabas, Oracle and DB2 have been undergoing upgrades since the 1970s. General-purpose DBMSs aim to meet the needs of as many applications as poss... |
Many other databases have application software that accesses the database on behalf of end-users, without exposing the DBMS interface directly. Application programmers may use a wire protocol directly, or more likely through an application programming interface. Database designers and database administrators interact w... |
The relational model, first proposed in 1970 by Edgar F. Codd, departed from this tradition by insisting that applications should search for data by content, rather than by following links. The relational model employs sets of ledger-style tables, each used for a different type of entity. Only in the mid-1980s did comp... |
As computers grew in speed and capability, a number of general-purpose database systems emerged; by the mid-1960s a number of such systems had come into commercial use. Interest in a standard began to grow, and Charles Bachman, author of one such product, the Integrated Data Store (IDS), founded the "Database Task Grou... |
IBM also had their own DBMS in 1966, known as Information Management System (IMS). IMS was a development of software written for the Apollo program on the System/360. IMS was generally similar in concept to CODASYL, but used a strict hierarchy for its model of data navigation instead of CODASYL's network model. Both co... |
In this paper, he described a new system for storing and working with large databases. Instead of records being stored in some sort of linked list of free-form records as in CODASYL, Codd's idea was to use a "table" of fixed-length records, with each table used for a different type of entity. A linked-list system would... |
The relational model also allowed the content of the database to evolve without constant rewriting of links and pointers. The relational part comes from entities referencing other entities in what is known as one-to-many relationship, like a traditional hierarchical model, and many-to-many relationship, like a navigati... |
For instance, a common use of a database system is to track information about users, their name, login information, various addresses and phone numbers. In the navigational approach all of this data would be placed in a single record, and unused items would simply not be placed in the database. In the relational approa... |
Linking the information back together is the key to this system. In the relational model, some bit of information was used as a "key", uniquely defining a particular record. When information was being collected about a user, information stored in the optional tables would be found by searching for this key. For instanc... |
Just as the navigational approach would require programs to loop in order to collect records, the relational approach would require loops to collect information about any one record. Codd's solution to the necessary looping was a set-oriented language, a suggestion that would later spawn the ubiquitous SQL. Using a bra... |
Codd's paper was picked up by two people at Berkeley, Eugene Wong and Michael Stonebraker. They started a project known as INGRES using funding that had already been allocated for a geographical database project and student programmers to produce code. Beginning in 1973, INGRES delivered its first test products which w... |
Another approach to hardware support for database management was ICL's CAFS accelerator, a hardware disk controller with programmable search capabilities. In the long term, these efforts were generally unsuccessful because specialized database machines could not keep pace with the rapid development and progress of gene... |
IBM started working on a prototype system loosely based on Codd's concepts as System R in the early 1970s. The first version was ready in 1974/5, and work then started on multi-table systems in which the data could be split so that all of the data for a record (some of which is optional) did not have to be stored in a ... |
The 1980s ushered in the age of desktop computing. The new computers empowered their users with spreadsheets like Lotus 1-2-3 and database software like dBASE. The dBASE product was lightweight and easy for any computer user to understand out of the box. C. Wayne Ratliff the creator of dBASE stated: "dBASE was differen... |
The 1990s, along with a rise in object-oriented programming, saw a growth in how data in various databases were handled. Programmers and designers began to treat the data in their databases as objects. That is to say that if a person's data were in a database, that person's attributes, such as their address, phone numb... |
XML databases are a type of structured document-oriented database that allows querying based on XML document attributes. XML databases are mostly used in enterprise database management, where XML is being used as the machine-to-machine data interoperability standard. XML database management systems include commercial s... |
In recent years there was a high demand for massively distributed databases with high partition tolerance but according to the CAP theorem it is impossible for a distributed system to simultaneously provide consistency, availability and partition tolerance guarantees. A distributed system can satisfy any two of these g... |
The first task of a database designer is to produce a conceptual data model that reflects the structure of the information to be held in the database. A common approach to this is to develop an entity-relationship model, often with the aid of drawing tools. Another popular approach is the Unified Modeling Language. A s... |
Having produced a conceptual data model that users are happy with, the next stage is to translate this into a schema that implements the relevant data structures within the database. This process is often called logical database design, and the output is a logical data model expressed in the form of a schema. Whereas t... |
The final stage of database design is to make the decisions that affect performance, scalability, recovery, security, and the like. This is often called physical database design. A key goal during this stage is data independence, meaning that the decisions made for performance optimization purposes should be invisible ... |
While there is typically only one conceptual (or logical) and physical (or internal) view of the data, there can be any number of different external views. This allows users to see database information in a more business-related way rather than from a technical, processing viewpoint. For example, a financial department... |
The conceptual view provides a level of indirection between internal and external. On one hand it provides a common view of the database, independent of different external view structures, and on the other hand it abstracts away details of how the data are stored or managed (internal level). In principle every level, a... |
Database storage is the container of the physical materialization of a database. It comprises the internal (physical) level in the database architecture. It also contains all the information needed (e.g., metadata, "data about the data", and internal data structures) to reconstruct the conceptual level and external lev... |
Database access control deals with controlling who (a person or a certain computer program) is allowed to access what information in the database. The information may comprise specific database objects (e.g., record types, specific records, data structures), certain computations over certain objects (e.g., query types,... |
This may be managed directly on an individual basis, or by the assignment of individuals and privileges to groups, or (in the most elaborate models) through the assignment of individuals and groups to roles which are then granted entitlements. Data security prevents unauthorized users from viewing or updating the datab... |
Database transactions can be used to introduce some level of fault tolerance and data integrity after recovery from a crash. A database transaction is a unit of work, typically encapsulating a number of operations over a database (e.g., reading a database object, writing, acquiring lock, etc.), an abstraction supported... |
A database built with one DBMS is not portable to another DBMS (i.e., the other DBMS cannot run it). However, in some situations it is desirable to move, migrate a database from one DBMS to another. The reasons are primarily economical (different DBMSs may have different total costs of ownership or TCOs), functional, a... |
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