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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Electron transport chain oxphos system in mitochondria 0.6136828715943649 3.1618355415622816 0.0015677807958112 0.612361732424074 0.6305789164856246 52 O75306,P14406,P05141,O43676,Q9UDW1,P21912,P03886,O75964,O14949,P56134,Q99643,O75438,P12236,O95168,P12235,P24539,P56385,Q9Y6M9,P13073,P51970,P00403,P20674 22
Nonalcoholic fatty liver disease 0.5619931134947435 2.8908846597856503 0.0038415908249016 0.9021959378161024 0.6305789164856246 55 O75306,P14406,O43676,Q9UDW1,P21912,O14949,Q99643,O75438,O96000,Q86Y39,O95168,Q9Y6M9,Q9P0J0,P13073,P42574,P51970,P00403,P54646,P20674 19
Cholesterol metabolism with bloch and kandutschrussell pathways 0.6931117783386829 2.838067035677436 0.0045387649235828 0.9359220020553932 0.6305789164856246 24 Q14739,P35610,Q14534,Q16850,Q15800,Q15392,P37268,O75845,Q9UBM7,O76062,Q15125 11
Alzheimers disease 0.5532954018451438 2.6239515950166483 0.0086916136584036 0.9948701663423026 0.6305789164856246 92 Q9BVA1,Q9NQC3,P49721,P42574,P07437,Q9BUF5,P16615,P68371,P04350,P45880,P12235,Q9Y277,Q13885,O95197,P12236,P21796 16
Sphingolipid metabolism overview 0.8998473935000096 2.5105222101675113 0.0120552738361361 0.9993415558790254 0.6305789164856246 8 O95470,Q96G23,Q06136,Q13510,Q16880,P27544 6
Sphingolipid metabolism integrated pathway 0.8998473935000096 2.5105222101675113 0.0120552738361361 0.9993415558790254 0.6305789164856246 8 O95470,Q96G23,Q06136,Q13510,Q16880,P27544 6
Sphingolipid pathway 0.8837059790609687 2.5018165395107315 0.0123557933674127 0.9994520834395938 0.6305789164856246 9 O95470,P04062,Q96G23,Q06136,Q13510,Q16880 6
Alzheimers disease and mirna effects 0.5377150614477394 2.4472006046202437 0.0143970682647893 0.9998429637408898 0.6305789164856246 94 Q9BVA1,Q9NQC3,P49721,P42574,P07437,Q9BUF5,P16615,P68371,P04350,P45880,P12235,Q9Y277,Q13885,O95197,P12236,P21796 16
Oxidation by cytochrome p450 0.9062810554393528 2.426080229613516 0.0152628957156721 0.9999076445532078 0.6305789164856246 6 Q6UW02,O43169,Q16850 3
Metapathway biotransformation phase i and ii 0.647416182399869 2.4068902160626005 0.0160890055860696 0.9999443697069932 0.6305789164856246 22 Q16850,Q06520,P21964,Q6UW02,P07099,Q99735,Q7LGA3 7
Ferroptosis 0.619692986602013 2.372797459765583 0.01765394161013 0.9999787302605158 0.6305789164856246 25 P37268,P09601,P45880,Q9NZ45,Q9Y277,Q15366 6
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.888428887221866 2.352134798463877 0.0186660091480546 0.9999885877171164 0.6305789164856246 6 P09601 1
Parkinubiquitin proteasomal system pathway 0.575144091675655 2.295081943093603 0.0217284286908245 0.9999982721836976 0.6305789164856246 38 Q9BVA1,P07437,P68371,P04350,Q13885 5
Pathogenic escherichia coli infection 0.5927199680118063 2.2126299480846243 0.0269231685700206 0.9999999306785066 0.6504637526516986 27 Q9BVA1,P07437,Q9BUF5,P68371,P04350,Q13885 6
Cholesterol biosynthesis with skeletal dysplasias 0.8377681924698086 2.188429568599206 0.028638326408191 0.9999999761162712 0.6652903519441313 7 Q14739,Q16850,Q15392,O75845,Q15125 5
Mitochondrial complex iv assembly 0.7669631957140505 2.158239101205795 0.0309092467838638 0.9999999941906492 0.6667566091947776 12 P14406,Q9Y2R0,P00403,P13073,Q9Y241 5
Sphingolipid metabolism in senescence 0.7713078217302316 2.1141579289529493 0.0345017808220673 0.999999999383558 0.6986510371218678 11 Q06136,P04062,Q13510,Q96G23 4
Kennedy pathway from sphingolipids 0.8166617211316088 2.048353381514531 0.0405253859228278 0.999999999985932 0.6986510371218678 6 O95470 1
Metabolism of spingolipids in er and golgi apparatus 0.9122857972698292 2.0033830015855276 0.0451361945773101 0.9999999999992332 0.6986510371218678 4 Q06136,O95470,Q16880 3
Mitochondrial complex iii assembly 0.766957267070799 1.9769044591413416 0.048052430697093 0.9999999999998792 0.6986510371218678 9 Q9UDW1 1
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6639079083015779 1.912983921334173 0.0557501108597398 0.9999999999999992 0.7405224486355723 16 P50402,P42167,O60725,O75844,P27338 5
Proteoglycan biosynthesis 0.8675573627650408 1.8245689130626548 0.068066108168683 1.0 0.7756967798846147 4 Q8TB61,Q9NX62,Q96L58 3
Glycerophospholipid biosynthetic pathway 0.7435474462988303 1.771265881084458 0.076516498316465 1.0 0.8252850889847297 7 P48651,Q9HCL2,Q86UL3,O95674 4
Glycerolipids and glycerophospholipids 0.7513090980004444 1.7628474336070223 0.0779262248333088 1.0 0.825744557882781 6 P48651,Q86UL3 2
Cholesterol biosynthesis pathway 0.6740094159942346 1.754752830207401 0.0793015951322093 1.0 0.8258304044802491 13 Q14534,Q16850,P37268,O75845,Q15800,Q9UBM7 6
Vitamin d metabolism 0.8328778503295027 1.684218028577116 0.0921395402907188 1.0 0.8398626521831698 4 P04062,P38435 2
Hostpathogen interaction of human coronaviruses apoptosis 0.7451278752318873 1.6798102444053993 0.0929942413223721 1.0 0.8398626521831698 5 P42574 1
Envelope proteins and their potential roles in edmd physiopathology 0.6030111132749016 1.6423857227243956 0.1005100918664427 1.0 0.8398626521831698 17 Q14739,P61586,P50402,P42167 4
Intracellular trafficking proteins involved in cmt neuropathy 0.7035536884665995 1.632046296106178 0.1026697337573225 1.0 0.8398626521831698 8 Q9NR77,Q15907 2
Familial partial lipodystrophy fpld 0.6920715783020681 1.578193390567966 0.1145211882021497 1.0 0.8868050983858775 8 O75844,O60725 2
Mitochondrial complex i assembly model oxphos system 0.5054389071799145 1.5689409453549652 0.1166617000046792 1.0 0.8892567871676558 25 O75306,O43676,O95168,P03886,Q96CU9,O75438,Q9Y6M9,Q9P0J0,Q9NPL8 9
Glycosylation and related congenital defects 0.6687626820495005 1.5117983128441368 0.1305851787609628 1.0 0.9389696187097808 9 Q9H3H5,O75352,Q9BT22,Q2TAA5 4
Progeriaassociated lipodystrophy 0.6510635132781465 1.471718261849349 0.1410969740624934 1.0 0.946917470374956 10 O75844,O60725 2
Influence of laminopathies on wnt signaling 0.6382712999755535 1.4565389551683243 0.1452436889755541 1.0 0.9482081167025778 11 O75844,P50402,O60725 3
Vitamin a and carotenoid metabolism 0.7757977930904045 1.4506641256757613 0.1468734095375548 1.0 0.9482081167025778 4 Q8WTV0 1
Mirna regulation of p53 pathway in prostate cancer 0.686345800911609 1.4177890332845098 0.1562523669107445 1.0 0.9535971241549096 5 O14681 1
Acquired partial lipodystrophy barraquersimons syndrome 0.6814845699168061 1.3959540949721077 0.1627283191652073 1.0 0.9622207505116348 5 O60725 1
Oxidative phosphorylation 0.4753083954130597 1.3914556037096115 0.1640873134150635 1.0 0.9622207505116348 31 O75306,Q86Y39,P51970,O95168,P24539,P03886,P56385,O75964,O75438,Q9Y6M9,P56134,O96000 12
Mitochondrial immune response to sarscov2 0.6392884676548188 1.3686648584889751 0.1711040598861055 1.0 0.9789783785906412 9 Q86UT6,Q99623,Q9Y6M9 3
Amyotrophic lateral sclerosis als 0.6223055827789069 1.3283500460538131 0.1840624938538515 1.0 0.9789783785906412 10 O96008,P20339,P42574,Q9BUN8 4
7oxoc and 7betahc pathways 0.6299238668117257 1.3229344715036933 0.1858571704778584 1.0 0.9789783785906412 9 O15118,Q9UBM7,Q15125 3
Nephrotic syndrome 0.5713364228463766 1.3195290278013654 0.1869923122808467 1.0 0.9789783785906412 15 O75844,Q14108 2
Neuroinflammation 0.6618631605409033 1.3076535602464692 0.1909908414623387 1.0 0.9859698140448938 5 P00403,P42345 2
Triacylglyceride synthesis 0.733892643645334 1.278043634855938 0.201234041236566 1.0 0.996273450056442 4 Q99943,Q9HCL2 2
Tryptophan metabolism 0.5625708585116769 1.2694265222237102 0.2042889817329094 1.0 1.0 15 Q15392,P27338,P51648 3
Endothelin pathways 0.6172825784756919 1.2610479916540225 0.2072915568595394 1.0 1.0 9 P16615,P00403 2
Ketogenesis and ketolysis 0.6248921328852285 1.22347338700298 0.2211509499225823 1.0 1.0 7 O43772,P35610,P53985 3
Dopamine metabolism 0.7150054258737786 1.200219446732155 0.2300541246743939 1.0 1.0 4 P21964 1
Pregnane x receptor pathway 0.6224574133488376 1.1299653391993456 0.2584908298258714 1.0 1.0 5 Q06520 1
Corticotropinreleasing hormone signaling pathway 0.4411006368418562 1.083165339884607 0.2787350410992801 1.0 1.0 23 P42892,Q06520,P42574,P61586 4
Sarscov2 and covid19 pathway 0.6852414318705706 1.0779500967700608 0.2810560269977968 1.0 1.0 4 Q8WTV0 1
Drug induction of bile acid pathway 0.9132075471698112 1.038011997127462 0.2992644697332478 1.0 1.0 2 Q06520 1
Nuclear receptors in lipid metabolism and toxicity 0.9132075471698112 1.038011997127461 0.2992644697332483 1.0 1.0 2 P28288 1
Ciliopathies 0.4463871852826027 1.0313433664101042 0.3023798286716379 1.0 1.0 22 O43924,Q15051,P57076,Q10713 4
Allograft rejection 0.5503397957341558 1.004076325824483 0.3153418255156808 1.0 1.0 11 P42574,Q9BY49,P08183,P49327,P10321 5
Oxysterols derived from cholesterol 0.5761734876702038 0.9951287465203912 0.3196736510577898 1.0 1.0 7 Q15125 1
Lung fibrosis 0.581533056721363 0.9925591653447366 0.3209248330002925 1.0 1.0 6 P09601,Q8IZ81 2
Camkk2 pathway 0.5353710622665371 0.9665615947943248 0.3337632413676799 1.0 1.0 12 P09601 1
Constitutive androstane receptor pathway 0.5752201539929462 0.9637350630412768 0.3351787705013791 1.0 1.0 6 Q06520 1
Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.6555542705750506 0.9569938142610936 0.3385703771929695 1.0 1.0 4 Q07820 1
Ethanol effects on histone modifications 0.5398923513012547 0.9501043223173112 0.342059247184677 1.0 1.0 11 P00374,O14929 2
Spinal cord injury 0.429584281726962 0.909305515195801 0.3631888801881473 1.0 1.0 22 P61586,Q9NQC3,P42574 3
Apoptosis modulation by hsp70 0.5532829900472461 0.8640120951413255 0.3875812462537791 1.0 1.0 6 P42574,P49327 2
Estrogen receptor pathway 0.7456810745354857 0.8129306493140774 0.4162578208299983 1.0 1.0 3 Q9HCL2 1
Aryl hydrocarbon receptor pathway wp2873 0.5496080339222615 0.8050083046414958 0.4208148875019049 1.0 1.0 5 Q15185,O00170,Q16543 3
Eicosanoid synthesis 0.7347859049954122 0.7731959199070007 0.4394064404613169 1.0 1.0 3 Q9H7Z7 1
Joubert syndrome 0.4411565404718544 0.7729761575105835 0.4395364911882278 1.0 1.0 19 O43924,P61586,P41208 3
Statin inhibition of cholesterol production 0.5213610912162117 0.7208858301977894 0.4709797616368822 1.0 1.0 6 Q8WTV0,Q14534,P37268 3
Ccl18 signaling pathway 0.4955576494235216 0.6931722137796643 0.4882014834602775 1.0 1.0 10 Q86UE4 1
Liver x receptor pathway 0.8145137880986923 0.6894686365458614 0.4905284035805368 1.0 1.0 2 P49327 1
Adipogenesis 0.4521617741674746 0.6791440516877641 0.497046592928265 1.0 1.0 16 Q9NZ45,P43490,O75844 3
Mitochondrial complex ii assembly 0.7053311050729051 0.6682780033619207 0.5039561516984539 1.0 1.0 3 P21912 1
Insulin signaling in adipocytes normal condition 0.5807546299351818 0.6622871870925812 0.5077871867798196 1.0 1.0 4 P42345,P62753 2
Insulin signaling in adipocytes diabetic condition 0.5807546299351818 0.6622871870925812 0.5077871867798196 1.0 1.0 4 P42345,P62753 2
Circadian rhythm genes 0.3625406954775185 0.6404191191723548 0.5219001562807213 1.0 1.0 45 Q03164,Q8WXF1,P11802,P43490,Q14103,Q00839,P54802,P49327,P04818,P23246,P00813,Q15233,P50416,P54646 14
Neural crest cell migration during development 0.493248846297382 0.6337558441237561 0.5262401740019618 1.0 1.0 8 P61586,O96013,P31751 3
P53 transcriptional gene network 0.4870664726900204 0.6269233137133806 0.530709504283974 1.0 1.0 9 Q9NQ88,Q709F0,Q7LG56,P49327 4
Serine metabolism 0.4909985991157217 0.6044858614703059 0.5455206663630445 1.0 1.0 7 P00374,P04818 2
Copper homeostasis 0.4912018428141619 0.5892496913769085 0.5556937875249031 1.0 1.0 6 O43819,P42574 2
Netrinunc5b signaling pathway 0.4438439798694802 0.5886794335070629 0.5560763368778909 1.0 1.0 15 P42574 1
15q112 copy number variation syndrome 0.5546992526234109 0.5654633750284918 0.5717586289229657 1.0 1.0 4 Q7L576,Q9BSJ2 2
Microglia pathogen phagocytosis pathway 0.4880883207437494 0.5442113333391706 0.5862960537574711 1.0 1.0 5 P52735,O00443,O15143,P07948 4
Mitochondrial fatty acid synthesis pathway 0.5488168497290504 0.5441969607262604 0.5863059430645956 1.0 1.0 4 Q53GQ0 1
Vitamin d receptor pathway 0.4403705086285878 0.5331446530651514 0.5939334508603429 1.0 1.0 14 Q5VV42,Q06520,P08183,Q96KA5 4
Disorders of folate metabolism and transport 0.4695318141298666 0.5265528233364938 0.5985041604527681 1.0 1.0 8 P00374 1
Neural crest cell migration in cancer 0.460927378968582 0.5058103558240323 0.6129897879315673 1.0 1.0 9 P61586,O96013,P31751 3
Heme biosynthesis 0.4763480700058251 0.4971269499532398 0.619099531015868 1.0 1.0 5 P22830,P36551 2
Synaptic signaling pathways associated with autism spectrum disorder 0.4319906865529512 0.3929822844274746 0.6943325659301731 1.0 1.0 10 P21359,P31751,P42345,P54646 4
Gastric cancer network 2 0.3800797513205476 0.3052415326931549 0.7601822022898912 1.0 1.0 17 Q86UE4 1
Mir517 relationship with arcn1 and usp1 0.6769230769230956 0.2951605137923668 0.767871264342304 1.0 1.0 2 P48444 1
Sting pathway in kawasakilike disease and covid19 0.4146140296321422 0.2721196844132532 0.7855299944850764 1.0 1.0 5 O00221,Q86UT6 2
Biomarkers for pyrimidine metabolism disorders 0.4057046950952704 0.2563448562162279 0.7976845637946772 1.0 1.0 7 Q7LG56,P04818,P12277 3
Hostpathogen interaction of human coronaviruses autophagy 0.4510601219866448 0.2367957130088084 0.81281527751153 1.0 1.0 4 Q99570,Q9NT62,P42345 3
Glucocorticoid receptor pathway 0.3990638927058115 0.2326469645947783 0.816035555275785 1.0 1.0 7 Q15185,P07900,P27105 3
Genes related to primary cilium development based on crispr 0.3842517008180046 0.2286919296842192 0.8191083677619004 1.0 1.0 13 A0AVF1,P63167,Q10713,Q8NCM8 4
Serotonin receptor 2 and elksrfgata4 signaling 0.5528455284552878 0.2234704486756262 0.8231693801416582 1.0 1.0 3 Q02750,P27361 2
Aryl hydrocarbon receptor pathway wp2586 0.3904469156107508 0.2175948995175615 0.8277447588729447 1.0 1.0 10 P07900,O00170,Q16543 3
Nuclear receptors metapathway 0.3078808894448857 0.2077780932194506 0.8354022383987125 1.0 1.0 49 O00767,P11802,O14880,P09601,P08183,P23786,P07900,Q16543,Q06520,P49327,Q9HCL2,Q15067,Q99735,O00170,Q15185,P50416,P27105 17
Mapk pathway in congenital thyroid cancer 0.6185776487663428 0.1807692706643225 0.856548684158676 1.0 1.0 2 P27361 1
Sterol regulatory elementbinding proteins srebp signaling 0.3192916738908961 0.1650070915964809 0.8689384002854559 1.0 1.0 34 O00767,Q15437,Q14534,Q16850,P42345,P37268,Q9NR31,P49327,Q8WTV0,Q9HCL2,P54646,P14324 12
1q211 copy number variation syndrome 0.3734217973378453 0.1529792815928156 0.8784146138555504 1.0 1.0 10 Q9NPH0 1
Mitochondrial long chain fatty acid betaoxidation 0.3603070549954836 0.138225257077769 0.8900623944302111 1.0 1.0 14 O43772,P50416,Q9BY49 3
Arrhythmogenic right ventricular cardiomyopathy 0.3626050592847841 0.1352573780920839 0.8924083826872509 1.0 1.0 13 P16615 1
Methionine de novo and salvage pathway 0.3689608323899409 0.1337766442570695 0.8935791963482576 1.0 1.0 9 Q13126,P19623,Q9BV57 3
Regulation of apoptosis by parathyroid hormonerelated protein 0.4023965774022808 0.1273524290086302 0.8986614657321663 1.0 1.0 4 Q07820 1
Mirna biogenesis 0.4994192799070884 0.1252769374996719 0.9003043095387517 1.0 1.0 3 Q9UPY3,P62826 2
Omega9 fatty acid synthesis 0.3626758535591571 0.123368111509748 0.9018156074733412 1.0 1.0 5 O00767,P49327 2
Hepatitis b infection 0.3125777086670612 0.1185157849728691 0.9056589886406456 1.0 1.0 28 Q15904,Q9Y277,P42574,P49327 4
Mevalonate arm of cholesterol biosynthesis pathway 0.3633295730561545 0.1170843567198358 0.906793205996751 1.0 1.0 10 P35610,P37268 2
Il18 signaling pathway 0.2831409445477901 0.1139466801703457 0.909280061093248 1.0 1.0 66 Q969N2,Q9NQX7,Q9UMR5,P42574,Q9Y6M7,O00221,P35613,P09601,P49327,Q86UL3,Q15031,O96008,Q9NZJ7,P50416 14
Vitamin b12 disorders 0.4857723577235812 0.1058090437451496 0.9157338612027216 1.0 1.0 3 Q99707,P22033 2
Autophagy 0.359976615401601 0.1055846732504723 0.9159118857437868 1.0 1.0 10 Q7Z3C6 1
Fatty acid betaoxidation 0.3173078009224083 0.0859826331363654 0.9314802228423018 1.0 1.0 21 O43772,P35610,P50416 3
Leptininsulin signaling overlap 0.5378809869375902 0.0829501558674505 0.9338911728092932 1.0 1.0 2 O14654 1
Pdgf pathway 0.3346543147120336 0.0719401451569941 0.9426495415839558 1.0 1.0 17 P61586 1
Ncrnas involved in stat3 signaling in hepatocellular carcinoma 0.4523809523809565 0.0673980521947104 0.9462648197883764 1.0 1.0 3 P23458,P40763 2
Neovascularisation processes 0.4523809523809564 0.0673980521947101 0.9462648197883764 1.0 1.0 3 P28482,P27361 2
Pi3kaktmtor vitd3 signaling 0.3337383669926478 0.0607084843782258 0.9515913745897304 1.0 1.0 5 P54646 1
Mrna protein and metabolite inducation pathway by cyclosporin a 0.4367015098722454 0.053572316596228 0.9572759129840884 1.0 1.0 3 Q15758,Q14145 2
Heart development 0.4335075493612123 0.0510598167099967 0.959277855821486 1.0 1.0 3 P35222,P28482 2
Cancer immunotherapy by pd1 blockade 0.4335075493612118 0.0510598167099964 0.9592778558214864 1.0 1.0 3 P40763,P04439 2
16p112 distal deletion syndrome 0.3403155723545938 0.0449900401404688 0.964115247733567 1.0 1.0 9 P52735,P20339,Q9H2V7 3
Pi3kaktmtor signaling pathway and therapeutic opportunities 0.4380261248185707 0.0376073106352783 0.9700007790028582 1.0 1.0 2 P42345 1
Aspirin and mirnas 0.4380261248185707 0.0376073106352783 0.9700007790028582 1.0 1.0 2 P53602 1
Wnt signaling 0.3350630692294623 0.0356873174382987 0.9715316833294744 1.0 1.0 14 P61586 1
Mfap5mediated ovarian cancer cell motility and invasiveness 0.3902439024390277 0.0258691190277303 0.9793617312457156 1.0 1.0 3 P28482,P27361 2
T cell receptor and costimulatory signaling 0.3091226031377057 0.0194380596865621 0.9844916488980956 1.0 1.0 5 Q15118,P48729,Q08209,P19174 4
Reninangiotensinaldosterone system raas 0.3702090592334531 0.0188326486846179 0.9849746085533349 1.0 1.0 3 P0DP25,Q13555 2
Oxidative damage response 0.327245829596078 0.0161479234365242 0.9871163811156702 1.0 1.0 8 P42574 1
15q133 copy number variation syndrome 0.3411730545876927 0.0123396236664591 0.9901546546434536 1.0 1.0 3 Q9BXW9,Q16658 2
Wnt signaling pathway 0.3303612441589806 0.0114773490266261 0.9908426014631344 1.0 1.0 12 P61586,Q9BTU6,P42345,P48729 4
Acetylcholine synthesis 0.3179442508710848 0.0093946953919952 0.9925042278566284 1.0 1.0 3 P49585,P35790 2
Pilocytic astrocytoma 0.2531939605110387 0.0065594616897131 0.9947663443216408 1.0 1.0 3 P21359,Q06124 2
Ovarian infertility 0.2985960752480167 0.0061437509763342 0.9950980267886336 1.0 1.0 4 P11802 1